Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	taste bud development	NTF4 BDNF	1.49e-05	2	80	2	GO:0061193
GeneOntologyCellularComponent	synaptic vesicle	SLC17A5 ATR NTF4 CLN3 DYSF BDNF STX6	1.77e-04	300	82	7	GO:0008021
GeneOntologyCellularComponent	exocytic vesicle	SLC17A5 ATR NTF4 CLN3 DYSF BDNF STX6	2.63e-04	320	82	7	GO:0070382
Domain	DUF3402	STRIP2 STRIP1	1.90e-05	2	82	2	PF11882
Domain	CCDC74_C	CCDC74B CCDC74A	1.90e-05	2	82	2	PF14917
Domain	CCDC74	CCDC74B CCDC74A	1.90e-05	2	82	2	IPR033226
Domain	N1221	STRIP2 STRIP1	1.90e-05	2	82	2	PF07923
Domain	CCDC74_C	CCDC74B CCDC74A	1.90e-05	2	82	2	IPR029422
Domain	DUF3402	STRIP2 STRIP1	1.90e-05	2	82	2	IPR021819
Domain	DUF3402	STRIP2 STRIP1	1.90e-05	2	82	2	SM01293
Domain	N1221	STRIP2 STRIP1	1.90e-05	2	82	2	SM01292
Domain	N1221	STRIP2 STRIP1	1.90e-05	2	82	2	IPR012486
Domain	ATPase_dyneun-rel_AAA	MDN1 DYNC2H1 DNAH11	2.87e-05	14	82	3	IPR011704
Domain	AAA_5	MDN1 DYNC2H1 DNAH11	2.87e-05	14	82	3	PF07728
Domain	WD40_repeat_dom	CFAP251 WDR97 FBXW4 BOP1 THOC3 ARHGEF17 BRWD3 BRWD1	4.78e-05	297	82	8	IPR017986
Domain	-	CFAP251 WDR97 FBXW4 BOP1 THOC3 ARHGEF17 BRWD3 BRWD1	1.06e-04	333	82	8	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	CFAP251 WDR97 FBXW4 BOP1 THOC3 ARHGEF17 BRWD3 BRWD1	1.11e-04	335	82	8	IPR015943
Domain	NGF	NTF4 BDNF	1.14e-04	4	82	2	PF00243
Domain	Nerve_growth_factor-like	NTF4 BDNF	1.14e-04	4	82	2	IPR020408
Domain	NGF_2	NTF4 BDNF	1.14e-04	4	82	2	PS50270
Domain	Nerve_growth_factor-rel	NTF4 BDNF	1.14e-04	4	82	2	IPR002072
Domain	Nerve_growth_factor_CS	NTF4 BDNF	1.14e-04	4	82	2	IPR019846
Domain	NGF_1	NTF4 BDNF	1.14e-04	4	82	2	PS00248
Domain	NGF	NTF4 BDNF	1.14e-04	4	82	2	SM00140
Domain	Nerve_growth_factor-rel	NTF4 BDNF	1.14e-04	4	82	2	PD002052
Domain	WD40	CFAP251 WDR97 FBXW4 BOP1 THOC3 BRWD3 BRWD1	1.43e-04	259	82	7	PF00400
Domain	WD40	CFAP251 WDR97 FBXW4 BOP1 THOC3 BRWD3 BRWD1	1.76e-04	268	82	7	SM00320
Domain	WD40_repeat	CFAP251 WDR97 FBXW4 BOP1 THOC3 BRWD3 BRWD1	1.93e-04	272	82	7	IPR001680
Domain	WD_REPEATS_1	CFAP251 WDR97 FBXW4 BOP1 THOC3 BRWD3 BRWD1	2.20e-04	278	82	7	PS00678
Domain	WD_REPEATS_2	CFAP251 WDR97 FBXW4 BOP1 THOC3 BRWD3 BRWD1	2.25e-04	279	82	7	PS50082
Domain	WD_REPEATS_REGION	CFAP251 WDR97 FBXW4 BOP1 THOC3 BRWD3 BRWD1	2.25e-04	279	82	7	PS50294
Domain	AAA+_ATPase	MDN1 DYNC2H1 ABCC5 RNF213 DNAH11	4.30e-04	144	82	5	IPR003593
Domain	AAA	MDN1 DYNC2H1 ABCC5 RNF213 DNAH11	4.30e-04	144	82	5	SM00382
Domain	DHC_N1	DYNC2H1 DNAH11	5.24e-04	8	82	2	PF08385
Domain	Dynein_heavy_dom-1	DYNC2H1 DNAH11	5.24e-04	8	82	2	IPR013594
Domain	F-box-like	FBXO10 FBXO44 FBXW4	9.49e-04	44	82	3	PF12937
Domain	FBOX	FBXO10 FBXO44 FBXW4	1.54e-03	52	82	3	SM00256
Domain	Dynein_heavy_chain_D4_dom	DYNC2H1 DNAH11	1.67e-03	14	82	2	IPR024317
Domain	Dynein_HC_stalk	DYNC2H1 DNAH11	1.67e-03	14	82	2	IPR024743
Domain	Myotubularin-like_Pase_dom	MTMR12 MTMR9	1.67e-03	14	82	2	IPR010569
Domain	Dynein_heavy_dom-2	DYNC2H1 DNAH11	1.67e-03	14	82	2	IPR013602
Domain	DHC_N2	DYNC2H1 DNAH11	1.67e-03	14	82	2	PF08393
Domain	MT	DYNC2H1 DNAH11	1.67e-03	14	82	2	PF12777
Domain	AAA_8	DYNC2H1 DNAH11	1.67e-03	14	82	2	PF12780
Domain	PPASE_MYOTUBULARIN	MTMR12 MTMR9	1.67e-03	14	82	2	PS51339
Domain	Myotubularin_fam	MTMR12 MTMR9	1.67e-03	14	82	2	IPR030564
Domain	Myotub-related	MTMR12 MTMR9	1.67e-03	14	82	2	PF06602
Domain	DHC_fam	DYNC2H1 DNAH11	1.93e-03	15	82	2	IPR026983
Domain	Dynein_heavy_dom	DYNC2H1 DNAH11	1.93e-03	15	82	2	IPR004273
Domain	Dynein_heavy	DYNC2H1 DNAH11	1.93e-03	15	82	2	PF03028
Domain	PI3/4_kinase_CS	ATR PIK3C2A	1.93e-03	15	82	2	IPR018936
Domain	-	ATR PIK3C2A	2.20e-03	16	82	2	1.10.1070.11
Domain	PI3Kc	ATR PIK3C2A	2.20e-03	16	82	2	SM00146
Domain	HEAT_type_2	ATR PPP4R4	2.48e-03	17	82	2	IPR021133
Domain	PI3/4_kinase_cat_dom	ATR PIK3C2A	2.78e-03	18	82	2	IPR000403
Domain	PI3_PI4_kinase	ATR PIK3C2A	2.78e-03	18	82	2	PF00454
Domain	PI3_4_KINASE_3	ATR PIK3C2A	2.78e-03	18	82	2	PS50290
Domain	PI3_4_KINASE_1	ATR PIK3C2A	2.78e-03	18	82	2	PS00915
Domain	PI3_4_KINASE_2	ATR PIK3C2A	2.78e-03	18	82	2	PS00916
Domain	F-box	FBXO10 FBXO44 FBXW4	3.19e-03	67	82	3	PF00646
Domain	HEAT_REPEAT	ATR ECPAS PPP4R4	3.61e-03	70	82	3	PS50077
Domain	ARM-type_fold	USP34 ATR PIK3C2A TTC12 ECPAS PPP4R4	3.77e-03	339	82	6	IPR016024
Domain	FBOX	FBXO10 FBXO44 FBXW4	3.91e-03	72	82	3	PS50181
Domain	F-box_dom	FBXO10 FBXO44 FBXW4	4.39e-03	75	82	3	IPR001810
Pubmed	Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.	BRWD3 STRIP2 STRIP1 BRWD1	7.89e-07	29	86	4	21834987
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MDN1 PNPLA6 ATR CLN3 TRAPPC10 ZNF579 RREB1 ECPAS COIL INTS3 STRIP1	3.32e-06	774	86	11	15302935
Pubmed	Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients.	ECPAS BRWD3 BRWD1	5.21e-06	14	86	3	28878358
Pubmed	Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae.	STRIP2 STRIP1	6.04e-06	2	86	2	12588993
Pubmed	Neurotrophin-4/5 is required for the early growth of regenerating axons in peripheral nerves.	NTF4 BDNF	6.04e-06	2	86	2	15926911
Pubmed	NT-4/5 antagonizes the BDNF modulation of corticostriatal transmission: Role of the TrkB.T1 receptor.	NTF4 BDNF	6.04e-06	2	86	2	30666798
Pubmed	The Impact of Physical Exercise on the Circulating Levels of BDNF and NT 4/5: A Review.	NTF4 BDNF	6.04e-06	2	86	2	34445512
Pubmed	Brain-derived neurotrophic factor and neurotrophin-4/5 are expressed in breast cancer and can be targeted to inhibit tumor cell survival.	NTF4 BDNF	6.04e-06	2	86	2	21350004
Pubmed	Ischemic brain damage in mice after selectively modifying BDNF or NT4 gene expression.	NTF4 BDNF	6.04e-06	2	86	2	10616802
Pubmed	Chromosomal mapping of two members of the human dynein gene family to chromosome regions 7p15 and 11q13 near the deafness loci DFNA 5 and DFNA 11.	DYNC2H1 DNAH11	6.04e-06	2	86	2	9325061
Pubmed	Sensory but not motor neuron deficits in mice lacking NT4 and BDNF.	NTF4 BDNF	6.04e-06	2	86	2	7746325
Pubmed	Neurotrophin 4 is required for the survival of a subclass of hair follicle receptors.	NTF4 BDNF	6.04e-06	2	86	2	9712673
Pubmed	Epithelial overexpression of BDNF or NT4 disrupts targeting of taste neurons that innervate the anterior tongue.	NTF4 BDNF	6.04e-06	2	86	2	11401409
Pubmed	BDNF but not NT-4 is required for normal flexion reflex plasticity and function.	NTF4 BDNF	6.04e-06	2	86	2	11438749
Pubmed	Differential expression and regulation by activin of the neurotrophins BDNF and NT4 during human and mouse ovarian development.	NTF4 BDNF	6.04e-06	2	86	2	20175187
Pubmed	Gustatory papillae and taste bud development and maintenance in the absence of TrkB ligands BDNF and NT-4.	NTF4 BDNF	6.04e-06	2	86	2	19629530
Pubmed	Brain-derived neurotrophic factor is required for normal development of the central respiratory rhythm in mice.	NTF4 BDNF	6.04e-06	2	86	2	9706001
Pubmed	Brain-derived neurotrophic factor (BDNF) is required for the enhancement of hippocampal neurogenesis following environmental enrichment.	NTF4 BDNF	6.04e-06	2	86	2	17040481
Pubmed	Lingual and palatal gustatory afferents each depend on both BDNF and NT-4, but the dependence is greater for lingual than palatal afferents.	NTF4 BDNF	6.04e-06	2	86	2	20575060
Pubmed	BDNF, but not NT-4, is necessary for normal development of Meissner corpuscles.	NTF4 BDNF	6.04e-06	2	86	2	15722178
Pubmed	TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae.	STRIP2 STRIP1	6.04e-06	2	86	2	22298706
Pubmed	Epithelial overexpression of BDNF and NT4 produces distinct gustatory axon morphologies that disrupt initial targeting.	NTF4 BDNF	6.04e-06	2	86	2	16500639
Pubmed	Early life stress combined with serotonin 3A receptor and brain-derived neurotrophic factor valine 66 to methionine genotypes impacts emotional brain and arousal correlates of risk for depression.	HTR3A BDNF	6.04e-06	2	86	2	20728877
Pubmed	Do BDNF and NT-4/5 exert synergistic or occlusive effects on corticostriatal transmission in a male mouse model of Huntington's disease?	NTF4 BDNF	6.04e-06	2	86	2	31392756
Pubmed	Hippocampal deletion of BDNF gene attenuates gamma oscillations in area CA1 by up-regulating 5-HT3 receptor.	HTR3A BDNF	6.04e-06	2	86	2	21298058
Pubmed	Role of neurotrophin-4/5 in neural cell death during retinal development and ischemic retinal injury in vivo.	NTF4 BDNF	6.04e-06	2	86	2	15671298
Pubmed	Neurotrophin-4, alone or heterodimerized with brain-derived neurotrophic factor, is sorted to the constitutive secretory pathway.	NTF4 BDNF	6.04e-06	2	86	2	12970359
Pubmed	CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment.	CCDC74B CCDC74A	6.04e-06	2	86	2	31521166
Pubmed	Mice lacking brain-derived neurotrophic factor exhibit visceral sensory neuron losses distinct from mice lacking NT4 and display a severe developmental deficit in control of breathing.	NTF4 BDNF	6.04e-06	2	86	2	8757249
Pubmed	Effect of neurotrophin-4/5 on bone/cementum-related protein expressions and DNA synthesis in cultures of human periodontal ligament cells.	NTF4 BDNF	6.04e-06	2	86	2	18980528
Pubmed	Degeneration of vestibular neurons in late embryogenesis of both heterozygous and homozygous BDNF null mutant mice.	NTF4 BDNF	6.04e-06	2	86	2	8674435
Pubmed	Composition and Regulation of the Cellular Repertoire of SCF Ubiquitin Ligases.	AKT3 FBXO10 FBXO44 FBXW4	1.74e-05	62	86	4	29103612
Pubmed	Neurotrophin effects on intracellular Ca2+ and force in airway smooth muscle.	NTF4 BDNF	1.81e-05	3	86	2	16648236
Pubmed	Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway.	NTF4 BDNF	1.81e-05	3	86	2	15987945
Pubmed	Tyrosine kinase B receptor and its activated neurotrophins in ovaries from human fetuses and adults.	NTF4 BDNF	1.81e-05	3	86	2	16648150
Pubmed	Brain-derived neurotrophic factor requirement for activity-dependent maturation of glutamatergic synapse in developing mouse somatosensory cortex.	NTF4 BDNF	1.81e-05	3	86	2	10700561
Pubmed	The protein factor-arrest 11 (Far11) is essential for the toxicity of human caspase-10 in yeast and participates in the regulation of autophagy and the DNA damage signaling.	STRIP2 STRIP1	1.81e-05	3	86	2	22782902
Pubmed	Regulation of preimplantation embryo development by brain-derived neurotrophic factor.	NTF4 BDNF	1.81e-05	3	86	2	17880937
Pubmed	Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities.	NTF4 BDNF	1.81e-05	3	86	2	10725924
Pubmed	Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4.	NTF4 BDNF	1.81e-05	3	86	2	7746324
Pubmed	Attenuation of a caspase-3 dependent cell death in NT4- and p75-deficient embryonic sensory neurons.	NTF4 BDNF	1.81e-05	3	86	2	10995552
Pubmed	Differential regulation of the nerve growth factor and brain-derived neurotrophic factor genes in L929 mouse fibroblasts.	NTF4 BDNF	1.81e-05	3	86	2	1336558
Pubmed	Neurotrophin 3, not brain-derived neurotrophic factor or neurotrophin 4, knockout mice have delay in vestibular compensation after unilateral labyrinthectomy.	NTF4 BDNF	1.81e-05	3	86	2	9591544
Pubmed	A discrete domain of the human TrkB receptor defines the binding sites for BDNF and NT-4.	NTF4 BDNF	1.81e-05	3	86	2	11855816
Pubmed	Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 complement and cooperate with each other sequentially during visceral neuron development.	NTF4 BDNF	1.81e-05	3	86	2	9348335
Pubmed	Differential expression of neurotrophins in postnatal C57BL/6 mice striatum.	NTF4 BDNF	1.81e-05	3	86	2	19173033
Pubmed	TrkB receptor signaling regulates developmental death dynamics, but not final number, of retinal ganglion cells.	NTF4 BDNF	1.81e-05	3	86	2	14602830
Pubmed	The STRIPAK complex components FAM40A and FAM40B regulate endothelial cell contractility via ROCKs.	STRIP2 STRIP1	1.81e-05	3	86	2	30509168
Pubmed	TrkB signaling regulates the developmental maturation of the somatosensory cortex.	NTF4 BDNF	1.81e-05	3	86	2	16009525
Pubmed	Severe peripheral sensory neuron loss and modest motor neuron reduction in mice with combined deficiency of brain-derived neurotrophic factor, neurotrophin 3 and neurotrophin 4/5.	NTF4 BDNF	1.81e-05	3	86	2	10822262
Pubmed	A new role for neurotrophins: involvement of brain-derived neurotrophic factor and neurotrophin-4 in hair cycle control.	NTF4 BDNF	1.81e-05	3	86	2	9973328
Pubmed	Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 act as "epitheliotrophins" in murine skin.	NTF4 BDNF	1.81e-05	3	86	2	10334567
Pubmed	Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain.	NTF4 BDNF	1.81e-05	3	86	2	2369898
Pubmed	The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site.	NTF4 BDNF	1.81e-05	3	86	2	10631974
Pubmed	The 3-D structure of a folate-dependent dehydrogenase/cyclohydrolase bifunctional enzyme at 1.5 A resolution.	NTF4 BDNF	1.81e-05	3	86	2	9519408
Pubmed	Developmental expression of Bdnf, Ntf4/5, and TrkB in the mouse peripheral taste system.	NTF4 BDNF	1.81e-05	3	86	2	21038447
Pubmed	Neurotrophin-4/5 (NT-4/5) and brain-derived neurotrophic factor (BDNF) act at later stages of cerebellar granule cell differentiation.	NTF4 BDNF	1.81e-05	3	86	2	7722620
Pubmed	The inorganic perspectives of neurotrophins and Alzheimer's disease.	NTF4 BDNF	3.61e-05	4	86	2	22192858
Pubmed	Structure of the brain-derived neurotrophic factor/neurotrophin 3 heterodimer.	NTF4 BDNF	3.61e-05	4	86	2	7703225
Pubmed	The sensory mechanotransduction ion channel ASIC2 (acid sensitive ion channel 2) is regulated by neurotrophin availability.	NTF4 BDNF	3.61e-05	4	86	2	15708491
Pubmed	Loss of brain-derived neurotrophic factor-dependent neural crest-derived sensory neurons in neurotrophin-4 mutant mice.	NTF4 BDNF	3.61e-05	4	86	2	10681461
Pubmed	BDNF is required for the normal development of taste neurons in vivo.	NTF4 BDNF	3.61e-05	4	86	2	9141083
Pubmed	The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 are survival and activation factors for eosinophils in patients with allergic bronchial asthma.	NTF4 BDNF	3.61e-05	4	86	2	12900521
Pubmed	Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.	DYNC2H1 RNF213	3.61e-05	4	86	2	26147384
Pubmed	Expression of nerve growth factor family neurotrophins in a mouse osteoblastic cell line.	NTF4 BDNF	3.61e-05	4	86	2	8117293
Pubmed	Dissociation equilibrium constant of beta nerve growth factor.	NTF4 BDNF	3.61e-05	4	86	2	925010
Pubmed	Stem cells from wildtype and Friedreich's ataxia mice present similar neuroprotective properties in dorsal root ganglia cells.	NTF4 BDNF	3.61e-05	4	86	2	23671637
Pubmed	The Crystal Structure of the Ubiquitin-like Domain of Ribosome Assembly Factor Ytm1 and Characterization of Its Interaction with the AAA-ATPase Midasin.	MDN1 BOP1	6.01e-05	5	86	2	26601951
Pubmed	Circulating levels of neurotrophic factors in autism spectrum disorders.	NTF4 BDNF	6.01e-05	5	86	2	25275256
Pubmed	PI3K-Akt signaling pathway upregulates hepatitis C virus RNA translation through the activation of SREBPs.	AKT3 SREBF1	6.01e-05	5	86	2	26855332
Pubmed	Formation of a full complement of cranial proprioceptors requires multiple neurotrophins.	NTF4 BDNF	6.01e-05	5	86	2	10842362
Pubmed	The role of neurotrophin receptors in female germ-cell survival in mouse and human.	NTF4 BDNF	6.01e-05	5	86	2	14507777
Pubmed	Neurotrophin binding to human alpha 2-macroglobulin under apparent equilibrium conditions.	NTF4 BDNF	6.01e-05	5	86	2	7537086
Pubmed	Association study of 10 genes encoding neurotrophic factors and their receptors in adult and child attention-deficit/hyperactivity disorder.	NTF4 BDNF	6.01e-05	5	86	2	18179783
Pubmed	Identification of maxillary factor, a maxillary process-derived chemoattractant for developing trigeminal sensory axons.	NTF4 BDNF	6.01e-05	5	86	2	10677035
Pubmed	Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.	FBXO10 FBXO44 FBXW4 RNF213	6.06e-05	85	86	4	19028597
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MDN1 FBXO10 DQX1 EXOC3L4 RNF213 ECPAS ARHGEF17 MTPAP MTMR9	8.73e-05	736	86	9	29676528
Pubmed	Expression of neurotrophins and their receptors in peripheral lung cells of mice.	NTF4 BDNF	9.01e-05	6	86	2	12122447
Pubmed	Differential induction of Pax genes by NGF and BDNF in cerebellar primary cultures.	NTF4 BDNF	9.01e-05	6	86	2	8163557
Pubmed	Downregulation of neurotrophic factors in the brain of a mouse model of Gaucher disease; implications for neuronal loss in Gaucher disease.	NTF4 BDNF	9.01e-05	6	86	2	16953113
Pubmed	STRIPAK components determine mode of cancer cell migration and metastasis.	STRIP2 STRIP1	9.01e-05	6	86	2	25531779
Pubmed	Taste neurons consist of both a large TrkB-receptor-dependent and a small TrkB-receptor-independent subpopulation.	NTF4 BDNF	9.01e-05	6	86	2	24386206
Pubmed	Expression patterns of neurotrophic factor mRNAs in developing human teeth.	NTF4 BDNF	9.01e-05	6	86	2	12397373
Pubmed	NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis.	NTF4 BDNF	9.01e-05	6	86	2	10985348
Pubmed	NRAGE associates with the anti-apoptotic factor Che-1 and regulates its degradation to induce cell death.	NTF4 BDNF	9.01e-05	6	86	2	17488777
Pubmed	Samp1 is functionally associated with the LINC complex and A-type lamina networks.	TMEM201 SUN1	9.01e-05	6	86	2	21610090
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	AMN DYNC2H1 TRAPPC10 DNAH11	1.14e-04	100	86	4	25807483
Pubmed	Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder.	HTR3A BDNF	1.26e-04	7	86	2	18982004
Pubmed	RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling.	ATR INTS3	1.26e-04	7	86	2	25916848
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	PDXDC1 USP34 STIM2 ABCC5 RNF213 UBAC2 COIL STRIP1 XPR1	1.31e-04	777	86	9	35844135
Pubmed	A family of mammalian F-box proteins.	FBXO10 FBXO44 FBXW4	1.56e-04	42	86	3	10531037
Pubmed	Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR.	NTF4 BDNF	1.68e-04	8	86	2	9640332
Pubmed	Differential dependency of cutaneous mechanoreceptors on neurotrophins, trk receptors, and P75 LNGFR.	NTF4 BDNF	1.68e-04	8	86	2	9331334
Pubmed	Role of neurotrophins in mouse neuronal development.	NTF4 BDNF	1.68e-04	8	86	2	8050673
Pubmed	The cellular and molecular basis of direction selectivity of Aδ-LTMRs.	NTF4 BDNF	1.68e-04	8	86	2	25525881
Pubmed	Novel metabolic role for BDNF in pancreatic β-cell insulin secretion.	NTF4 BDNF	1.68e-04	8	86	2	32327658
Pubmed	Pacinian corpuscle development involves multiple Trk signaling pathways.	NTF4 BDNF	1.68e-04	8	86	2	15376326
Pubmed	Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.	PNPLA6 UBAC2 ATP4A BRWD3 BRWD1	1.75e-04	209	86	5	26389662
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	USP34 TMEM201 STIM2 ERP44 ATR ACKR3 SUN1 SREBF1 RNF213 UBAC2 BDNF	1.82e-04	1201	86	11	35696571
Pubmed	EARP is a multisubunit tethering complex involved in endocytic recycling.	VPS50 STX6	2.15e-04	9	86	2	25799061
Interaction	GPR182 interactions	PDXDC1 TMEM201 MDN1 ATR PIK3C2A SUN1 VPS50 RNF213 UBAC2 ECPAS MTPAP XPR1	3.45e-07	455	83	12	int:GPR182
Interaction	CMKLR1 interactions	PDXDC1 VPS50 UBAC2 ECPAS GPRC5B XPR1	3.77e-06	101	83	6	int:CMKLR1
Interaction	RHOF interactions	PDXDC1 TMEM201 STIM2 MDN1 ATR PIK3C2A SUN1 ABCC5 ECPAS MTPAP STX6 XPR1	1.93e-05	673	83	12	int:RHOF
Interaction	GPR17 interactions	PDXDC1 MDN1 ATR SACS VPS50 RNF213 ECPAS INTS3	2.17e-05	283	83	8	int:GPR17
Interaction	APLNR interactions	PDXDC1 TMEM201 MDN1 VPS50 UBAC2 ECPAS XPR1	2.64e-05	211	83	7	int:APLNR
Interaction	ZKSCAN5 interactions	ZSCAN21 THOC3 ZKSCAN5	3.63e-05	16	83	3	int:ZKSCAN5
Interaction	C3orf52 interactions	SLC12A6 TMEM201 PNPLA6 SUN1 SREBF1 ABCC5 UBAC2 XPR1	3.70e-05	305	83	8	int:C3orf52
Interaction	TMEM9 interactions	PDXDC1 SLC12A6 MDN1 ATR VPS50 STX6 XPR1	4.10e-05	226	83	7	int:TMEM9
Interaction	PIGH interactions	SLC12A6 TMEM201 STIM2 SUN1 SREBF1 UBAC2	5.38e-05	161	83	6	int:PIGH
Interaction	STX6 interactions	PDXDC1 SLC12A6 STIM2 PIK3C2A VPS50 TRAPPC10 STX6 GPRC5B XPR1	9.38e-05	448	83	9	int:STX6
Interaction	C3orf18 interactions	MDN1 ATR SACS DYNC2H1 ECPAS	1.13e-04	115	83	5	int:C3orf18
GeneFamily	WD repeat domain containing	CFAP251 WDR97 FBXW4 BOP1 THOC3 BRWD3 BRWD1	2.77e-05	262	61	7	362
GeneFamily	Myotubularins\|Phosphoinositide phosphatases	MTMR12 MTMR9	1.14e-03	15	61	2	903
GeneFamily	Protein phosphatase catalytic subunits\|STRIPAK complex	STRIP2 STRIP1	2.05e-03	20	61	2	1371
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC74B TMEM201 CFAP251 WDR97 DQX1 CLN3	1.12e-06	174	86	6	e2243f1e48e3275753a2b3a69d06eefce69a8ded
ToppCell	IIH-CD8-CD4_Treg\|IIH / Condition, Cell_class and T cell subcluster	TMEM201 FBXW4 C20orf204 ECPAS MTPAP	2.60e-05	180	86	5	d1a8b25115c80e5a5bd0b8244167a98250ab9778
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	2.96e-05	185	86	5	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	Ciliated_cells-B-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	3.12e-05	187	86	5	2b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	3.20e-05	188	86	5	5ba5cbb403518026e9040379fb5d99339ea977d8
ToppCell	21-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	3.20e-05	188	86	5	803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)\|343B / Donor, Lineage, Cell class and subclass (all cells)	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	3.36e-05	190	86	5	169e600e95878000acf5d11f813f9028c7249646
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	3.36e-05	190	86	5	0cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCell	15-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	3.62e-05	193	86	5	aa3acc7571405169efb656d214f3a8cbf988362e
ToppCell	cellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	3.81e-05	195	86	5	d8bf15aa7cdbc5f29b58e1e6cff76c257f0ea12e
ToppCell	cellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	3.81e-05	195	86	5	e7f069f557a59ee7b502ff82ad4c9f47fa619ba8
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	3.90e-05	196	86	5	a37ba02446eef5d1fab703204583f6550a8ec3e1
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	3.90e-05	196	86	5	89ea4d2086e1c769c5a87f1471a6cd4acabcfe33
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	3.90e-05	196	86	5	a156840330630e518bc85633dded6f2c3ead3b30
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	3.90e-05	196	86	5	009e83c7251cf300be78b263634d233a8d972a68
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	4.00e-05	197	86	5	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	4.19e-05	199	86	5	92fdf6e2f0786ab2ab78126e9131a93794168139
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	4.29e-05	200	86	5	cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	4.29e-05	200	86	5	79e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	4.29e-05	200	86	5	873def69bf55ccbfc944bc10c5afc06be019c312
ToppCell	Biopsy_IPF-Epithelial-Differentiating_Ciliated\|Biopsy_IPF / Sample group, Lineage and Cell type	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	4.29e-05	200	86	5	8dfce65e417d6dcacb871d93d1539cdf807002fe
ToppCell	Biopsy_IPF-Epithelial-Ciliated\|Biopsy_IPF / Sample group, Lineage and Cell type	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	4.29e-05	200	86	5	bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	4.29e-05	200	86	5	7cb3e3bd9e851ccb096e0a3471819471d85ebace
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CCDC74B CFAP251 DYNC2H1 CCDC74A DNAH11	4.29e-05	200	86	5	8441e289377215a6877640946fe3f6de1f456502
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated\|Lung / Manually curated celltypes from each tissue	C2CD3 C20orf204 THOC3 INTS3	2.09e-04	151	86	4	9bfb807e1180b31fa9a2c500ce993de9707c070f
ToppCell	10x5'-Liver-Myeloid_Mac-Intestinal_macrophages\|Liver / Manually curated celltypes from each tissue	PIEZO2 EXOC3L4 ABCC5 TDRD10	2.37e-04	156	86	4	9a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SPACA7 HTR3A OTOP2	2.58e-04	64	86	3	0f13fbeda23ab9df3488cfae98cb6cd7a3c1b332
ToppCell	3'_v3-Lung-Lymphocytic_B-ABC_aged-B_memory\|Lung / Manually curated celltypes from each tissue	FBXO10 HTR3A FBXO44 CCDC74A	2.86e-04	164	86	4	7766900740f67dbbe3c4d90fbfdcc1665cee6515
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	PIM3 AKT3 C2CD3 DYNC2H1	3.21e-04	169	86	4	625788d86f0ceebcf2653a251db1f1a9f9746d29
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Microglia/Mac\|Myeloid_cells / Location, Cell class and cell subclass	TMEM201 CFAP251 ABCC5 ZKSCAN5	3.21e-04	169	86	4	dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCell	356C-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PIEZO2 EXOC3L4 HCAR1 DNAH11	3.21e-04	169	86	4	44d201361eb497222a4972a0e10bac1e05dcfd0a
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKT3 PIEZO2 SACS HCAR1	3.43e-04	172	86	4	073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STIM2 ACKR3 NDST2 BRWD1	3.43e-04	172	86	4	8a6a2b4c6654bc976e60a02d0e7303a9071ed55f
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	STIM2 CFAP251 HTR3A SUN1	3.58e-04	174	86	4	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 HCAR1 PHTF2 ARHGEF17	3.66e-04	175	86	4	1b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIEZO2 DYNC2H1 ARHGEF17 BDNF	3.99e-04	179	86	4	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	RSV-Healthy-0\|RSV / Virus stimulation, Condition and Cluster	PDXDC1 USP34 FBXO10 TRAPPC10	4.07e-04	180	86	4	974044056e2f7e909cb11c6f6ca89e58bf95f7e5
ToppCell	RSV-Healthy-0\|Healthy / Virus stimulation, Condition and Cluster	PDXDC1 USP34 FBXO10 TRAPPC10	4.07e-04	180	86	4	703a1d0f9536af94d56757eb01221878d7b7fe61
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP251 DYNC2H1 CCDC74A DNAH11	4.07e-04	180	86	4	1f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	USP34 AKT3 RNF213 THOC3	4.16e-04	181	86	4	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIEZO2 ACKR3 DYSF GPRC5B	4.25e-04	182	86	4	fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIEZO2 ACKR3 DYSF GPRC5B	4.43e-04	184	86	4	453295362888c9a59d0e73c7a5b15914c50ff591
ToppCell	Ciliated_cells-A-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CCDC74B CFAP251 CCDC74A DNAH11	4.43e-04	184	86	4	07c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCell	10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Mega-Mast\|bone_marrow / Manually curated celltypes from each tissue	EXOC3L4 ARHGEF17 BDNF STRIP2	4.52e-04	185	86	4	a62ebaff92f2ed27b27b32c27c89cfbe2cb35116
ToppCell	Ciliated_cells-B-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	CCDC74B CFAP251 CCDC74A DNAH11	4.61e-04	186	86	4	f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP251 DYNC2H1 CCDC74A DNAH11	4.61e-04	186	86	4	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	390C-Epithelial_cells-Epithelial-F_(Ciliated)\|390C / Donor, Lineage, Cell class and subclass (all cells)	CCDC74B CFAP251 CCDC74A DNAH11	4.61e-04	186	86	4	708c5edefe36c91df27cf53c1b5101fb2030cc5a
ToppCell	18-Distal-Epithelial-Multiciliated_precursor\|Distal / Age, Tissue, Lineage and Cell class	CCDC74B CFAP251 CCDC74A PPP4R4	4.61e-04	186	86	4	58ab1360a1730655a5939295ba05997ac4a2d14e
ToppCell	390C-Epithelial_cells-Epithelial-F_(Ciliated)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	CCDC74B CFAP251 CCDC74A DNAH11	4.61e-04	186	86	4	029390c4aaf64e6bcd86124cd4a6dd2e6f3a374b
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 HCAR1 PHTF2 ARHGEF17	4.70e-04	187	86	4	ac8e092b37e042975e2ee057d3f7c6821e58e8b5
ToppCell	normal_Lung-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	HTR3A TRAPPC10 BRWD3 GPRC5B	4.70e-04	187	86	4	a3592f056e1c2f82ba325fea2ecc4dd6c6347c81
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 HCAR1 PHTF2 ARHGEF17	4.70e-04	187	86	4	d591a3c216997663ab77710fed0d230ffc37e41a
ToppCell	390C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCDC74B CFAP251 CCDC74A DNAH11	4.70e-04	187	86	4	88f785932e67c613db0dda84496de351359ed962
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCDC74A PORCN ARHGEF17 DNAH11	4.70e-04	187	86	4	150023e6a50c9da461f2321074d2d5e96caafb06
ToppCell	390C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCDC74B CFAP251 CCDC74A DNAH11	4.70e-04	187	86	4	8896a00b30d11b90ca42726d4e122174a30b161b
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 HCAR1 PHTF2 ARHGEF17	4.70e-04	187	86	4	d1dc8c9a2c2cd10c640257161a75e7730ec5bb41
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCDC74B DYNC2H1 CCDC74A DNAH11	4.80e-04	188	86	4	da59b5c0a4b11690a39a964c1a0a83e66aa0972b
ToppCell	multiciliated\|World / shred by cell class for bronchial biopsy	CCDC74B DYNC2H1 CCDC74A DNAH11	4.80e-04	188	86	4	6833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCell	Ciliated_cells-B-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	CCDC74B CFAP251 CCDC74A DNAH11	4.80e-04	188	86	4	606907c865bd2f11bb6474932716550f7723d858
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCDC74B DYNC2H1 CCDC74A DNAH11	4.80e-04	188	86	4	82c006f43c93f4a867953a446864f02b44536a23
ToppCell	(7)_Epithelial-F_(Ciliated)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CCDC74B CFAP251 CCDC74A DNAH11	4.80e-04	188	86	4	9a8b9f745eed9f129b6c582f48fbbaaacbebb4b3
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCDC74B CFAP251 DYNC2H1 CCDC74A	4.90e-04	189	86	4	57ab947b81dbd9d3e896be89e28c4a62cf720837
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCDC74B CFAP251 DYNC2H1 CCDC74A	4.90e-04	189	86	4	ebc16b8eab84167d74446783d7e802acedc6b9c6
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CCDC74B CFAP251 CCDC74A DNAH11	4.90e-04	189	86	4	dc440015949a768188c67661b6be63b1ead1a0f0
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CCDC74B CFAP251 CCDC74A DNAH11	4.90e-04	189	86	4	a3cd4c2da4feb9bdcd8957f3e344d095da1367b8
ToppCell	Multiciliated\|World / shred by cell class for nasal brushing	CCDC74B CFAP251 CCDC74A DNAH11	4.90e-04	189	86	4	34b110aef839376228c5a403a6b5047a945f472b
ToppCell	Ciliated\|World / shred by cell class for parenchyma	CCDC74B CFAP251 CCDC74A DNAH11	4.90e-04	189	86	4	711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma\|TCGA-Lung / Sample_Type by Project: Shred V9	DQX1 ACKR3 ABCC5 THOC3	4.90e-04	189	86	4	aa4f7d7a5196e5ae481ebc2549de8e3f0ef6e6be
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CCDC74B CFAP251 CCDC74A DNAH11	4.90e-04	189	86	4	93b1026bb1ba759e5704561c9a5de14a30c08894
ToppCell	Ciliated_cells-A\|World / lung cells shred on cell class, cell subclass, sample id	CCDC74B CFAP251 CCDC74A DNAH11	4.99e-04	190	86	4	cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCell	Epithelial_cells-Ciliated_cells-B\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	CCDC74B CFAP251 CCDC74A DNAH11	4.99e-04	190	86	4	426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCell	Transplant_Alveoli_and_parenchyma-Endothelial-Lymphatic\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	PIEZO2 ACKR3 DYSF GPRC5B	4.99e-04	190	86	4	8d6ec2fc0af19a5cb16fff34f8b131b71b33d45f
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP251 DYNC2H1 CCDC74A DNAH11	4.99e-04	190	86	4	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	Epithelial_cells-Ciliated_cells-A\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	CCDC74B CFAP251 CCDC74A DNAH11	4.99e-04	190	86	4	549d813a8f23b175875e53347928941f143e236c
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP251 DYNC2H1 CCDC74A DNAH11	4.99e-04	190	86	4	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	Ciliated_cells-B\|World / lung cells shred on cell class, cell subclass, sample id	CCDC74B CFAP251 CCDC74A DNAH11	4.99e-04	190	86	4	7031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	CCDC74B CFAP251 CCDC74A DNAH11	4.99e-04	190	86	4	a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCell	BAL-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	7b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)\|356C / Donor, Lineage, Cell class and subclass (all cells)	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	e314dd8f1a841cab847ae3703bedfe1bc623ac61
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	8a5a2188b13ef4bbfd626a42565566708a751c1b
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	9f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	dad675251e129254955eac179c84a641a4864586
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCell	Control-Epithelial\|Control / Disease group,lineage and cell class （2021.01.30）	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	b78547dae8328244a47c83346447bdd787efbcae
ToppCell	Control-Epithelial-Ciliated_cells\|Control / Condition, Lineage and Cell class	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	6d2cf41ee946137c039ddcc13593fc3f670afbba
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	b4e335e798c9617356b8e24412f9270c42dce656
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	c4b223b33c020a064f576711a3d700eb60a2d737
ToppCell	BAL-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	5129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCell	Control-Epithelial-Ciliated\|Control / Disease group,lineage and cell class （2021.01.30）	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCell	Control-Epithelial\|Control / Condition, Lineage and Cell class	CCDC74B CFAP251 CCDC74A DNAH11	5.09e-04	191	86	4	6228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCell	normal_Lung-Epithelial_cells-Ciliated\|normal_Lung / Location, Cell class and cell subclass	CCDC74B CFAP251 CCDC74A DNAH11	5.19e-04	192	86	4	097a13121820ab4e5cd2365600efccf5ea4ce8c3
ToppCell	LAM-Epithelial-AirwayEpi\|LAM / Condition, Lineage and Cell class	CCDC74B CFAP251 CCDC74A DNAH11	5.19e-04	192	86	4	7404fc65be3b7bd09447725b43fa31819004dfee
ToppCell	multiciliated\|World / shred by cell class for turbinate	CFAP251 DYNC2H1 CCDC74A DNAH11	5.19e-04	192	86	4	0f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	USP34 ATR PIK3C2A TRAPPC10	5.30e-04	193	86	4	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIM3 GIMAP2 C20orf204 DYSF	5.30e-04	193	86	4	0f2967afbbf4e538b63f985c0acc2e5d9aab7589
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	CFAP251 DYNC2H1 CCDC74A DNAH11	5.40e-04	194	86	4	958e648138676d46698090b4046cb484083ae449
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	CFAP251 DYNC2H1 CCDC74A DNAH11	5.40e-04	194	86	4	7a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
Disease	Polydactyly	AKT3 C2CD3 PNPLA6 DYNC2H1 PORCN	1.92e-05	117	82	5	C0152427
Disease	indoleacetate measurement	AKT3 ACKR3	3.38e-04	10	82	2	EFO_0021015
Disease	puberty onset measurement	KCNA7 ECPAS BDNF BRWD1	4.16e-04	125	82	4	EFO_0005677
Disease	Saldino-Noonan Syndrome	C2CD3 DYNC2H1	6.79e-04	14	82	2	C0036069
Disease	coffee consumption, cups of coffee per day measurement	CYP1A1 BDNF	8.93e-04	16	82	2	EFO_0004330, EFO_0006782
Disease	neuroimaging measurement, brain volume measurement	PDXDC1 USP34 AKT3 ATR STX6	1.23e-03	286	82	5	EFO_0004346, EFO_0006930
Disease	age at menarche	USP34 AKT3 PDXDC2P ECPAS BDNF GPRC5B BRWD1	1.34e-03	594	82	7	EFO_0004703
Disease	insomnia measurement	PDXDC1 PIK3C2A C20orf204 RREB1 GPRC5B DNAH11	1.48e-03	443	82	6	EFO_0007876

Protein segments in the cluster

Peptide	Gene	Start	Entry
SLRLWEVATARCVRT	BOP1	436	Q14137
LQPLFRVVCTRDWLT	EXOC3L4	526	Q17RC7
IGWRFIRIDTSCVCT	BDNF	226	P23560
RQLLLRALDAVATCW	C20orf204	161	A0A1B0GTL2
LILSLDSTRWRQLCL	FBXO10	36	Q9UK96
IAWLLCLREQSTSQR	HTR3A	351	P46098
REVTLLERWIQDLCT	GUSBP11	106	Q6P575
LERWIQDLCTRVVLR	GUSBP11	111	Q6P575
ILASLRAFQSCWVLR	ACTL9	386	Q8TC94
FNDLLLRCRELDTWT	DNAH11	4351	Q96DT5
LRCRELDTWTQDLTL	DNAH11	4356	Q96DT5
VRVWCLRTCAPVAVL	BRWD3	246	Q6RI45
RVLLWLQLCALTQAV	AMN	6	Q9BXJ7
TLRQCEVLIRELWNT	CCDC74A	271	Q96AQ1
TLRQCEVLIRELWNT	CCDC74B	271	Q96LY2
TFIIRCLQWTTVIER	AKT3	71	Q9Y243
IISCLCVSEDRRWIA	CFAP251	301	Q8TBY9
RWIRIDTACVCTLLS	NTF4	191	P34130
RRVCTLLVFTSWLVS	OR6C1	136	Q96RD1
SVIFCLVFWVIRASR	CYP1A1	16	P04798
CRTQLVWLVRELVKS	INTS3	141	Q68E01
CLRITALLVCEELLW	ARHGEF17	1921	Q96PE2
RLTCSDTRFKQLWIL	OR8U8	186	P0C7N1
TPWTVRCLRQADCIL	PNPLA6	861	Q8IY17
LSEQWIILRNLLSCV	MDN1	4246	Q9NU22
VFLLFLDCVWQILRQ	MTMR9	396	Q96QG7
LLESSSWLDIIRRCL	MTMR12	356	Q9C0I1
WRVRESSCLALNDLL	ECPAS	1176	Q5VYK3
CRKWDTEIRLQLLTF	PIK3C2A	496	O00443
RILSDTTLWLCRIFR	PDXDC1	116	Q6P996
RILSDTTLWLCRIFR	PDXDC2P	116	Q6P474
ILQCWSDVRFERFLL	KIR3DL3	141	Q8N743
RLVCSLWRDLIDLVT	FBXO44	31	Q9H4M3
FWLLVDLNRCRVVTD	COIL	26	P38432
ITNRWDLRVALFLTC	OR5C1	21	Q8NGR4
LDSRVRALVFSVRCW	MTPAP	346	Q9NVV4
ARQDIRSVWRAILSC	HECTD4	3421	Q9Y4D8
TLLRFCWDRLLLQEV	DQX1	141	Q8TE96
SQWRRQCLKDISLFL	OTOP2	486	Q7RTS6
CFSCLLSQAWRVRRL	GPRC5B	136	Q9NZH0
LDQIWLLLAICLACR	PORCN	26	Q9H237
VWIFCRTRLILSIVC	ABCC5	171	O15440
RRFLCTESEQLIWKS	DYNC2H1	3241	Q8NCM8
CIEFSNWIITRLLRI	ATR	96	Q13535
CICWFSFELLVRLLV	KCNA7	216	Q96RP8
QLRCFLKLTVNRVIW	C2CD3	36	Q4AC94
CIQLFLRLIILWLCI	GIMAP2	276	Q9UG22
LAFWRLICDTFRKIV	CACNA1G	726	O43497
RRVVCILVWLLAFCV	ACKR3	161	P25106
IIRVWCLRTCAPVAV	BRWD1	251	Q9NSI6
DLRCSLLLLVTWVFT	ERP44	11	Q9BS26
LAQVCRWLRRFTSCD	FBXW4	51	P57775
IILFCSFKIVWSLRR	HCAR1	191	Q9BXC0
WRKCSIRIFTVAQLE	SLC12A6	936	Q9UHW9
WNFSTLCVRRIFSLI	SLC17A5	356	Q9NRA2
FQLCRRIISEGIWSL	SACS	2421	Q9NZJ4
FFLRCIIWNTRDVIL	DYSF	1811	O75923
SETWRALCRVLTLCN	ATP4A	426	P20648
ITCIFLIISLWRHNR	TAS2R10	191	Q9NYW0
VIWCISLTLFLLRFV	PHTF2	671	Q8N3S3
LCCWQETELRPRTVI	SPACA7	16	Q96KW9
WNRLRFLDTCEFIIE	PPP4R4	581	Q6NUP7
FCWRNLFSCINLLRL	STRIP2	656	Q9ULQ0
FLVLLLRECFRDLSW	TDRD10	171	Q5VZ19
CWRNLFSCINLLRIL	STRIP1	661	Q5VSL9
DRRQWCAIAILFAVL	STX6	231	O43752
CRILETDLLSAIQFW	TBATA	236	Q96M53
LFLCDLLLVVRTSLW	SREBF1	971	P36956
SLRCCRIRFTWALAL	CLN3	336	Q13286
VQCIPAWLRFIQCLR	XPR1	451	Q9UBH6
LSLRKEFICWVREAL	RNF213	1421	Q63HN8
ILWEHCIRLANRTIV	VPS50	846	Q96JG6
EALSQLRVLCCEWLR	ZSCAN21	61	Q9Y5A6
RISQAWCETNLRRCI	RREB1	296	Q92766
SELTTCLRERLFRWQ	STIM2	421	Q9P246
CTVRIWTAENRLLRL	WDR97	711	A6NE52
LVCVRCFSRLDWPVR	THOC3	256	Q96J01
IASLTIWLLCRNIVQ	PIEZO2	131	Q9H5I5
TFESLVRFLQCWTRL	NDST2	541	P52849
RRIDAFCTCLWALLL	TMEM201	321	Q5SNT2
RVSPECQQLIRWCLS	PIM3	261	Q86V86
VWAVEVSRRCLSLLN	TTC12	516	Q9H892
VTLISWLNVFLLTRC	SUN1	271	O94901
WLNVFLLTRCLRNIC	SUN1	276	O94901
DFQIWRLICGRIICL	UBAC2	51	Q8NBM4
LLCSLVCWFTDRQIR	USP34	886	Q70CQ2
CWVFLSCLEVLQRIE	TRAPPC10	356	P48553
LCITIWRTLEITSRL	XKRX	241	Q6PP77
QVLLQADWTLLCLRC	ZNF579	221	Q8NAF0
EALSQLRVLCCEWLR	ZKSCAN5	66	Q9Y2L8