Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone binding	BPTF BRD2 IPO7 TSPYL2 BAZ1B MLLT3	5.03e-05	265	50	6	GO:0042393
GeneOntologyMolecularFunction	chromatin binding	URI1 BRD2 UBTF TSPYL2 ANKRD17 MLLT3 APP PAF1 HP1BP3	7.96e-05	739	50	9	GO:0003682
GeneOntologyBiologicalProcess	protein-DNA complex organization	BPTF SETD1B BRD2 BAZ2B UBTF TAF7L TSPYL2 BAZ1B MLLT3 APP TRIP12 HP1BP3	3.44e-06	999	50	12	GO:0071824
GeneOntologyBiologicalProcess	regulation of cell cycle	RAD51AP1 WAPL PTPRC IPO7 TSPYL2 PLCB1 BAZ1B ANKRD17 FGFR1 APP PAF1 TFDP2	3.45e-05	1256	50	12	GO:0051726
GeneOntologyBiologicalProcess	chromatin organization	BPTF SETD1B BRD2 BAZ2B TSPYL2 BAZ1B MLLT3 APP TRIP12 HP1BP3	4.81e-05	896	50	10	GO:0006325
GeneOntologyBiologicalProcess	chromatin remodeling	BPTF SETD1B BRD2 BAZ2B TSPYL2 BAZ1B APP TRIP12 HP1BP3	6.35e-05	741	50	9	GO:0006338
GeneOntologyBiologicalProcess	positive regulation of cell cycle process	RAD51AP1 PLCB1 ANKRD17 FGFR1 APP PAF1	9.49e-05	307	50	6	GO:0090068
GeneOntologyCellularComponent	nuclear speck	WBP11 SETD1B BRD2 PLCB1 RNF34 TRIP12 HP1BP3	6.14e-05	431	49	7	GO:0016607
GeneOntologyCellularComponent	eukaryotic translation initiation factor 3 complex, eIF3m	EIF3C EIF3CL	1.92e-04	9	49	2	GO:0071541
GeneOntologyCellularComponent	nuclear protein-containing complex	BPTF ZC3H11A SETD1B IPO7 TAF7L BAZ1B FIP1L1 MLLT3 PAF1 THOC5 TFDP2	2.77e-04	1377	49	11	GO:0140513
GeneOntologyCellularComponent	transcription export complex	ZC3H11A THOC5	3.50e-04	12	49	2	GO:0000346
GeneOntologyCellularComponent	chromosomal region	RAD51AP1 WAPL PPP1R12A BAZ1B THOC5 NGDN	4.33e-04	421	49	6	GO:0098687
GeneOntologyCellularComponent	ISWI-type complex	BPTF BAZ1B	4.81e-04	14	49	2	GO:0031010
GeneOntologyCellularComponent	chromatin	BPTF RAD51AP1 WAPL BRD2 BAZ2B TSPYL2 PLCB1 BAZ1B ANKRD17 TFDP2 HP1BP3	5.14e-04	1480	49	11	GO:0000785
GeneOntologyCellularComponent	eukaryotic translation initiation factor 3 complex	EIF3C EIF3CL	6.33e-04	16	49	2	GO:0005852
GeneOntologyCellularComponent	eukaryotic 48S preinitiation complex	EIF3C EIF3CL	8.04e-04	18	49	2	GO:0033290
GeneOntologyCellularComponent	eukaryotic 43S preinitiation complex	EIF3C EIF3CL	8.97e-04	19	49	2	GO:0016282
GeneOntologyCellularComponent	translation preinitiation complex	EIF3C EIF3CL	9.95e-04	20	49	2	GO:0070993
GeneOntologyCellularComponent	nuclear body	WBP11 UBE2O SETD1B BRD2 PLCB1 RNF34 TRIP12 HP1BP3	1.10e-03	903	49	8	GO:0016604
HumanPheno	Disinhibition	BPTF WBP11 UBTF PPP1R12A BAZ1B ANKRD17 FGFR1 HERC2 APP TRIP12	6.32e-05	807	17	10	HP:0000734
HumanPheno	Inappropriate behavior	BPTF WBP11 UBTF PPP1R12A BAZ1B ANKRD17 FGFR1 HERC2 APP TRIP12	6.32e-05	807	17	10	HP:0000719
HumanPheno	Abnormal response to social norms	BPTF WBP11 UBTF PPP1R12A BAZ1B ANKRD17 FGFR1 HERC2 APP TRIP12	6.32e-05	807	17	10	HP:5200123
HumanPheno	Social disinhibition	BPTF WBP11 UBTF PPP1R12A BAZ1B ANKRD17 FGFR1 HERC2 APP TRIP12	6.32e-05	807	17	10	HP:5200029
HumanPheno	Reduced impulse control	BPTF WBP11 UBTF PPP1R12A BAZ1B FIP1L1 ANKRD17 FGFR1 HERC2 APP TRIP12	8.29e-05	1032	17	11	HP:5200045
HumanPheno	Recurrent maladaptive behavior	BPTF WBP11 SETD1B UBTF PPP1R12A BAZ1B FIP1L1 ANKRD17 FGFR1 HERC2 APP TRIP12	1.14e-04	1293	17	12	HP:5200241
HumanPheno	Abnormally increased volition	BPTF WBP11 UBTF PPP1R12A BAZ1B ANKRD17 FGFR1 HERC2 APP TRIP12	1.22e-04	869	17	10	HP:5200263
HumanPheno	Abnormal social development	BPTF WBP11 UBTF PPP1R12A BAZ1B ANKRD17 FGFR1 HERC2 APP TRIP12	1.79e-04	908	17	10	HP:0025732
HumanPheno	Hyperactivity	WBP11 UBTF PPP1R12A BAZ1B ANKRD17 FGFR1 HERC2 TRIP12	1.95e-04	558	17	8	HP:0000752
HumanPheno	Impairment in personality functioning	BPTF WBP11 SETD1B UBTF PPP1R12A BAZ1B ANKRD17 FGFR1 HERC2 APP TRIP12	2.18e-04	1141	17	11	HP:0031466
Domain	DDT	BPTF BAZ2B BAZ1B	1.59e-07	5	48	3	SM00571
Domain	DDT_dom	BPTF BAZ2B BAZ1B	1.59e-07	5	48	3	IPR018501
Domain	WSD	BPTF BAZ2B BAZ1B	1.59e-07	5	48	3	PF15613
Domain	WHIM2_dom	BPTF BAZ2B BAZ1B	1.59e-07	5	48	3	IPR028941
Domain	DDT	BPTF BAZ2B BAZ1B	3.17e-07	6	48	3	PS50827
Domain	Bromodomain_CS	BPTF BRD2 BAZ2B BAZ1B	5.51e-07	26	48	4	IPR018359
Domain	BROMODOMAIN_1	BPTF BRD2 BAZ2B BAZ1B	2.38e-06	37	48	4	PS00633
Domain	Bromodomain	BPTF BRD2 BAZ2B BAZ1B	2.66e-06	38	48	4	PF00439
Domain	BROMODOMAIN_2	BPTF BRD2 BAZ2B BAZ1B	3.63e-06	41	48	4	PS50014
Domain	BROMO	BPTF BRD2 BAZ2B BAZ1B	4.00e-06	42	48	4	SM00297
Domain	Bromodomain	BPTF BRD2 BAZ2B BAZ1B	4.00e-06	42	48	4	IPR001487
Domain	-	BPTF BRD2 BAZ2B BAZ1B	4.00e-06	42	48	4	1.20.920.10
Domain	EIF3C_N_dom	EIF3C EIF3CL	6.47e-06	2	48	2	IPR008905
Domain	eIF-3c_N	EIF3C EIF3CL	6.47e-06	2	48	2	PF05470
Domain	EIF3C	EIF3C EIF3CL	6.47e-06	2	48	2	IPR027516
Domain	DDT	BPTF BAZ2B	3.87e-05	4	48	2	PF02791
Domain	WHIM1	BPTF BAZ1B	6.44e-05	5	48	2	PF15612
Domain	WHIM1_dom	BPTF BAZ1B	6.44e-05	5	48	2	IPR028942
Domain	Znf_FYVE_PHD	BPTF BAZ2B RNF34 BAZ1B	5.48e-04	147	48	4	IPR011011
Domain	PINT	EIF3C EIF3CL	7.58e-04	16	48	2	SM00088
Domain	PCI	EIF3C EIF3CL	8.58e-04	17	48	2	PF01399
Domain	PCI_dom	EIF3C EIF3CL	8.58e-04	17	48	2	IPR000717
Domain	PHD	BPTF BAZ2B BAZ1B	9.45e-04	75	48	3	PF00628
Domain	Znf_PHD-finger	BPTF BAZ2B BAZ1B	1.10e-03	79	48	3	IPR019787
Domain	PHD	BPTF BAZ2B BAZ1B	1.55e-03	89	48	3	SM00249
Domain	Znf_PHD	BPTF BAZ2B BAZ1B	1.65e-03	91	48	3	IPR001965
Domain	ZF_PHD_2	BPTF BAZ2B BAZ1B	1.87e-03	95	48	3	PS50016
Domain	ZF_PHD_1	BPTF BAZ2B BAZ1B	1.92e-03	96	48	3	PS01359
Domain	HECT	HERC2 TRIP12	2.18e-03	27	48	2	PF00632
Domain	HECTc	HERC2 TRIP12	2.18e-03	27	48	2	SM00119
Domain	HECT_dom	HERC2 TRIP12	2.18e-03	27	48	2	IPR000569
Domain	HECT	HERC2 TRIP12	2.18e-03	27	48	2	PS50237
Domain	-	EIF3C TFDP2 HP1BP3 EIF3CL	2.35e-03	218	48	4	1.10.10.10
Domain	WHTH_DNA-bd_dom	EIF3C TFDP2 HP1BP3 EIF3CL	3.42e-03	242	48	4	IPR011991
Pathway	BIOCARTA_TUBBY_PATHWAY	PLCB1 TUB	5.96e-05	5	35	2	MM1585
Pathway	BIOCARTA_TUBBY_PATHWAY	PLCB1 TUB	5.96e-05	5	35	2	M22076
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	ZC3H11A WAPL UBTF NOM1 PPP1R12A TSPYL2 BAZ1B FIP1L1 ANKRD17 EIF3C TRIP12 DNTTIP2 HP1BP3 NOL8 NGDN	5.67e-13	847	50	15	35850772
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	BPTF RAD51AP1 UBE2O WAPL BRD2 IPO7 BAZ2B UBTF BAZ1B HERC2 TRIP12 DNTTIP2 HP1BP3	2.46e-12	608	50	13	36089195
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	BPTF RAD51AP1 WBP11 ZC3H11A WAPL BRD2 BAZ2B UBTF BAZ1B FIP1L1 PAF1 TRIP12 DNTTIP2 HP1BP3 NOL8	3.09e-12	954	50	15	36373674
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ZSCAN29 BPTF ZC3H11A BRD2 BAZ2B UBTF NOM1 BAZ1B FIP1L1 PAF1 TRIP12 THOC5 DNTTIP2 HP1BP3 NOL8 NGDN	1.84e-11	1294	50	16	30804502
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	BPTF WBP11 ZC3H11A WAPL BRD2 UBTF BAZ1B FIP1L1 EIF3C PAF1 TRIP12 DNTTIP2 NOL8 NGDN	7.47e-11	989	50	14	36424410
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	BPTF WBP11 ZC3H11A BRD2 IPO7 UBTF BAZ1B FIP1L1 EIF3C HERC2 APP TRIP12 DNTTIP2 HP1BP3	1.18e-10	1024	50	14	24711643
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	BPTF URI1 BRD2 UBTF NOM1 BAZ1B HERC2 TRIP12 DNTTIP2 HP1BP3 EIF3CL	2.15e-10	533	50	11	30554943
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	BPTF ZC3H11A WAPL PTPRC BRD2 BAZ1B FIP1L1 ANKRD17 EIF3C TRIP12 STRIP1 EIF3CL	7.59e-10	774	50	12	15302935
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	ZC3H11A IPO7 UBTF NOM1 PPP1R12A BAZ1B ANKRD17 TRIP12 THOC5 DNTTIP2 HP1BP3 EIF3CL NOL8 NGDN	1.68e-09	1257	50	14	36526897
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	BPTF ZC3H11A UBE2O IPO7 UBTF BAZ1B ANKRD17 HERC2 TRIP12 DNTTIP2 HP1BP3	1.81e-09	653	50	11	22586326
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	WBP11 BRD2 UBTF PPP1R12A BAZ1B EIF3C PAF1 TRIP12 THOC5 DNTTIP2 HP1BP3	2.02e-09	660	50	11	32780723
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	BPTF RAD51AP1 WAPL BRD2 PPP1R12A TAF7L TSPYL2 BAZ1B FIP1L1 ANKRD17 APP DNTTIP2 TFDP2	4.20e-09	1116	50	13	31753913
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ZC3H11A UBE2O WAPL UBTF PPP1R12A BAZ1B ANKRD17 EIF3C PAF1 DNTTIP2 HP1BP3 NOL8	6.23e-09	934	50	12	33916271
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	BPTF ZC3H11A UBTF NOM1 BAZ1B HERC2 TRIP12 DNTTIP2 HP1BP3 NOL8 NGDN	8.57e-09	759	50	11	35915203
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	WAPL SETD1B UBTF TSPYL2 FIP1L1 ANKRD17 HERC2 TRIP12 DNTTIP2	1.21e-08	440	50	9	34244565
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	WBP11 BRD2 UBTF NOM1 BAZ1B FIP1L1 EIF3C PAF1 HP1BP3 NGDN	1.30e-08	605	50	10	28977666
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	WBP11 UBE2O BRD2 IPO7 UBTF BAZ1B HERC2 APP PAF1 THOC5 DNTTIP2 DMXL1 HP1BP3 NOL8	1.42e-08	1487	50	14	33957083
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	BPTF WBP11 ZC3H11A WAPL BRD2 IPO7 UBTF BAZ1B FIP1L1 PAF1 THOC5 HP1BP3	1.55e-08	1014	50	12	32416067
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	BPTF WBP11 ZC3H11A BRD2 IPO7 UBTF NOM1 TSPYL2 TRIP12	2.10e-08	469	50	9	27634302
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	IPO7 UBTF BAZ1B PAF1 TRIP12 DNTTIP2 HP1BP3 NGDN	2.40e-08	332	50	8	25693804
Pubmed	Tagging genes with cassette-exchange sites.	BPTF RAD51AP1 TMED8 BAZ1B EIF3C TRIP12 DMXL1 EIF3CL	2.57e-08	335	50	8	15741177
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	IPO7 BAZ2B UBTF BAZ1B TRIP12 DNTTIP2 HP1BP3 NGDN	2.89e-08	340	50	8	29478914
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	WBP11 ZC3H11A BAZ1B FIP1L1 DNTTIP2 NOL8	7.30e-08	148	50	6	32538781
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	IPO7 PPP1R12A ANKRD17 EIF3C TRIP12 EIF3CL	8.90e-08	153	50	6	26365490
Pubmed	BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.	URI1 SETD1B IFT46 APP PAF1 DNTTIP2 EIF3CL NOL8	1.43e-07	419	50	8	33001583
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	BPTF ZC3H11A WAPL BAZ1B TRIP12 DNTTIP2 NOL8	1.62e-07	283	50	7	30585729
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	WBP11 ZC3H11A UBE2O UBTF NOM1 FIP1L1 EIF3C DNTTIP2 NOL8 NGDN	1.90e-07	807	50	10	22681889
Pubmed	USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.	BAZ1B ANKRD17 TRIP12 DNTTIP2 HP1BP3	2.00e-07	90	50	5	35654790
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ZC3H11A WAPL PTPRC TTLL3 UBTF PPP1R12A BAZ1B ANKRD17 TRIP12 TUB DNTTIP2	3.14e-07	1084	50	11	11544199
Pubmed	A comprehensive resource of interacting protein regions for refining human transcription factor networks.	URI1 UBTF NOM1 PPP1R12A BAZ1B APP	3.30e-07	191	50	6	20195357
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ZC3H11A WAPL SETD1B IPO7 UBTF BAZ1B FIP1L1 ANKRD17 HERC2 TRIP12 DNTTIP2 NGDN	3.53e-07	1353	50	12	29467282
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	BRD2 UBTF BAZ1B PAF1 DNTTIP2 HP1BP3	3.72e-07	195	50	6	19454010
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	BPTF WAPL BAZ1B FIP1L1 EIF3C PAF1 HP1BP3	5.70e-07	341	50	7	32971831
Pubmed	Human transcription factor protein interaction networks.	BPTF WBP11 UBE2O BRD2 UBTF BAZ1B FIP1L1 ANKRD17 EIF3C HERC2 TFDP2 HP1BP3	6.30e-07	1429	50	12	35140242
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	BAZ1B EIF3C TRIP12 DNTTIP2 HP1BP3 NOL8 NGDN	6.65e-07	349	50	7	25665578
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	NOM1 PPP1R12A FIP1L1 ANKRD17 PAF1 TRIP12 THOC5 NOL8 NGDN	8.17e-07	724	50	9	36232890
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	IPO7 UBTF NOM1 PPP1R12A FIP1L1 EIF3C DNTTIP2 HP1BP3 EIF3CL NGDN	8.33e-07	949	50	10	36574265
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ZC3H11A BRD2 NOM1 PPP1R12A BAZ1B ANKRD17 EIF3C HERC2 APP STRIP1 NOL8 NGDN	1.03e-06	1497	50	12	31527615
Pubmed	The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.	URI1 UBTF ANKRD17 FGFR1 EIF3C EIF3CL	1.41e-06	245	50	6	19521500
Pubmed	The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.	BRD2 UBTF BAZ1B MLLT3	1.41e-06	57	50	4	21555454
Pubmed	FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3.	UBTF NOM1 FIP1L1 DNTTIP2 NOL8 NGDN	1.51e-06	248	50	6	27926873
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	BPTF SETD1B BRD2 BAZ1B FIP1L1 HP1BP3	1.62e-06	251	50	6	31076518
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	WBP11 UBTF BAZ1B ANKRD17 PAF1 HP1BP3	1.62e-06	251	50	6	28077445
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	WBP11 UBE2O WAPL BRD2 TSPYL2 FIP1L1 MLLT3 EIF3C HERC2 APP TRIP12	1.67e-06	1285	50	11	35914814
Pubmed	EIF3C Promotes Lung Cancer Tumorigenesis by Regulating the APP/HSPA1A/LMNB1 Axis.	EIF3C EIF3CL	2.03e-06	2	50	2	36157221
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	WBP11 URI1 PTPRC BRD2 IPO7 UBTF EIF3C HERC2 APP PAF1	2.05e-06	1049	50	10	27880917
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	BRD2 IPO7 UBTF NOM1 BAZ1B PAF1 TRIP12 HP1BP3	2.15e-06	601	50	8	33658012
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	BPTF SETD1B BAZ2B BAZ1B MLLT3	3.16e-06	157	50	5	30186101
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	BPTF BRD2 BAZ2B BAZ1B	4.26e-06	75	50	4	25593309
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	ZC3H11A PTPRC UBTF PPP1R12A FIP1L1 EIF3C TRIP12 EIF3CL	6.66e-06	701	50	8	30196744
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	BPTF ZC3H11A BAZ1B FGFR1	7.36e-06	86	50	4	37253089
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	ZC3H11A BRD2 UBTF FIP1L1 PAF1 DNTTIP2	9.08e-06	339	50	6	30415952
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	URI1 UBE2O BRD2 FIP1L1 MLLT3 HERC2 APP	1.08e-05	533	50	7	25544563
Pubmed	Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies.	EIF3C EIF3CL	1.21e-05	4	50	2	10504338
Pubmed	Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.	WAPL EIF3CL	1.21e-05	4	50	2	18187866
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	WBP11 URI1 PPP1R12A FIP1L1 PAF1 HP1BP3	1.30e-05	361	50	6	30344098
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	BPTF ZC3H11A UBE2O WAPL PPP1R12A BAZ1B PAF1	1.30e-05	549	50	7	38280479
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	WAPL ANKRD17 HERC2 TRIP12 STRIP1	1.36e-05	212	50	5	33853758
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ZC3H11A NOM1 FIP1L1 TRIP12 STRIP1 DMXL1 HP1BP3 NOL8	1.40e-05	777	50	8	35844135
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	BRD2 UBTF BAZ1B TRIP12	1.50e-05	103	50	4	32744500
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	BRD2 BAZ2B UBTF PAF1 NOL8	1.70e-05	222	50	5	37071664
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	URI1 UBE2O IPO7 NOM1 PPP1R12A FIP1L1 IFT46 EIF3C PAF1 HP1BP3	1.70e-05	1335	50	10	29229926
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	HIVEP3 BPTF URI1 BRD2 UBTF BAZ1B PAF1 TFDP2	1.86e-05	808	50	8	20412781
Pubmed	Frameshift mutations of ubiquitination-related genes HERC2, HERC3, TRIP12, UBE2Q1 and UBE4B in gastric and colorectal carcinomas with microsatellite instability.	HERC2 TRIP12	2.02e-05	5	50	2	22124266
Pubmed	A novel family of bromodomain genes.	BAZ2B BAZ1B	2.02e-05	5	50	2	10662543
Pubmed	TdIF2 is a nucleolar protein that promotes rRNA gene promoter activity.	UBTF DNTTIP2	2.02e-05	5	50	2	21668587
Pubmed	METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.	BRD2 IPO7 UBTF EIF3C EIF3CL	2.06e-05	231	50	5	36597993
Pubmed	Nuclear High Mobility Group A2 (HMGA2) Interactome Revealed by Biotin Proximity Labeling.	BRD2 TRIP12 DNTTIP2	2.10e-05	37	50	3	36835656
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	ZSCAN29 BPTF WBP11 BRD2 FIP1L1 EIF3C TRIP12 THOC5 HP1BP3	2.10e-05	1082	50	9	38697112
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	WBP11 IPO7 NOM1 FIP1L1 ANKRD17 HERC2 TRIP12 THOC5 HP1BP3 NGDN	2.14e-05	1371	50	10	36244648
Pubmed	Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study.	BAZ2B BAZ1B	3.03e-05	6	50	2	20802025
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	BPTF RAD51AP1 WBP11 BRD2 PPP1R12A FGFR1 TRIP12 DNTTIP2 HP1BP3 NGDN	3.28e-05	1442	50	10	35575683
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	ZC3H11A BRD2 UBTF FIP1L1 EIF3C HP1BP3	3.98e-05	441	50	6	31239290
Pubmed	Capturing novel mouse genes encoding chromosomal and other nuclear proteins.	PPP1R12A TRIP12	4.23e-05	7	50	2	9701556
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	HIVEP3 BPTF URI1 ZC3H11A TTLL3 PPP1R12A TSPYL2 ANKRD17 APP HP1BP3	4.31e-05	1489	50	10	28611215
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	BRD2 PPP1R12A NRK FGFR1 EIF3C DNTTIP2 TFDP2 EIF3CL	4.32e-05	910	50	8	36736316
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	BPTF WAPL EIF3C EIF3CL NOL8	4.40e-05	271	50	5	32433965
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	UBE2O NOM1 PPP1R12A FIP1L1 PAF1 THOC5 HP1BP3	4.64e-05	670	50	7	22990118
Pubmed	Global landscape of HIV-human protein complexes.	UBE2O PPP1R12A ANKRD17 EIF3C HERC2 APP	4.85e-05	457	50	6	22190034
Pubmed	Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin.	MLLT3 PAF1	5.64e-05	8	50	2	21873227
Pubmed	Mechanism of client selection by the protein quality-control factor UBE2O.	UBE2O IPO7	5.64e-05	8	50	2	35915257
Pubmed	RAD21 cooperates with pluripotency transcription factors in the maintenance of embryonic stem cell identity.	WAPL TRIP12 THOC5 DNTTIP2	5.91e-05	146	50	4	21589869
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	WBP11 UBE2O PPP1R12A PLCB1 ANKRD17 HERC2 PAF1 STRIP1	6.43e-05	963	50	8	28671696
Pubmed	Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1.	RNF34 CCDC136	7.25e-05	9	50	2	35170427
Pubmed	The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling.	EIF3C EIF3CL	7.25e-05	9	50	2	21292980
Pubmed	The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control.	EIF3C EIF3CL	7.25e-05	9	50	2	24003236
Pubmed	Transcriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cure.	MLLT3 PAF1	7.25e-05	9	50	2	24565118
Pubmed	The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase II.	URI1 PAF1	7.25e-05	9	50	2	15923622
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	WBP11 ZC3H11A FIP1L1 EIF3C DNTTIP2 EIF3CL NOL8	7.49e-05	723	50	7	34133714
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	BPTF UBE2O SETD1B BRD2 TRIP12 TFDP2	7.54e-05	495	50	6	27705803
Pubmed	Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.	ZC3H11A WAPL BAZ1B TRIP12	7.64e-05	156	50	4	37108203
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	WBP11 ZC3H11A FIP1L1 EIF3C THOC5 HP1BP3 NGDN	8.02e-05	731	50	7	29298432
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	ZC3H11A FIP1L1 EIF3C TRIP12 STRIP1 EIF3CL	8.23e-05	503	50	6	16964243
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	RAD51AP1 UBE2O IPO7 ANKRD17 EIF3C HERC2 TRIP12 STRIP1	8.65e-05	1005	50	8	19615732
Pubmed	mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events.	EIF3C EIF3CL	9.05e-05	10	50	2	16286006
Pubmed	Conservation and diversity of eukaryotic translation initiation factor eIF3.	EIF3C EIF3CL	9.05e-05	10	50	2	8995409
Pubmed	Comparative architectural aspects of regions of conserved synteny on human chromosome 11p15.3 and mouse chromosome 7 (including genes WEE1 and LMO1).	IPO7 TUB	9.05e-05	10	50	2	11528126
Pubmed	Developmental dynamics of two bipotent thymic epithelial progenitor types.	PTPRC FGFR1	9.05e-05	10	50	2	35614226
Pubmed	Human ALKBH4 interacts with proteins associated with transcription.	MLLT3 EIF3C	9.05e-05	10	50	2	23145062
Pubmed	A neurogenomics approach to gene expression analysis in the developing brain.	BAZ1B EIF3C TRIP12 EIF3CL	1.06e-04	170	50	4	15582152
Interaction	DOT1L interactions	ZC3H11A WAPL UBTF NOM1 PPP1R12A TSPYL2 BAZ1B FIP1L1 MLLT3 EIF3C TRIP12 DNTTIP2 HP1BP3 NOL8 NGDN	5.83e-10	807	50	15	int:DOT1L
Interaction	ZNF330 interactions	RAD51AP1 WBP11 UBE2O BRD2 IPO7 UBTF BAZ1B PAF1 TRIP12 DNTTIP2 HP1BP3 NOL8	6.76e-10	446	50	12	int:ZNF330
Interaction	H1-2 interactions	ZC3H11A UBE2O SETD1B BRD2 IPO7 BAZ1B FIP1L1 CASQ2 APP PAF1 THOC5 DNTTIP2 HP1BP3	5.74e-09	666	50	13	int:H1-2
Interaction	SMC5 interactions	BPTF RAD51AP1 WBP11 ZC3H11A WAPL BRD2 BAZ2B UBTF BAZ1B FIP1L1 PAF1 TRIP12 DNTTIP2 HP1BP3 NOL8	1.08e-08	1000	50	15	int:SMC5
Interaction	MEN1 interactions	BPTF ZC3H11A WAPL SETD1B UBTF NOM1 BAZ1B FIP1L1 ANKRD17 EIF3C PAF1 TRIP12 DNTTIP2 HP1BP3 NOL8	1.58e-08	1029	50	15	int:MEN1
Interaction	H3-3A interactions	BPTF RAD51AP1 WAPL SETD1B BRD2 UBTF BAZ1B MLLT3 FGFR1 HERC2 TRIP12 DNTTIP2 HP1BP3	2.32e-08	749	50	13	int:H3-3A
Interaction	H3C1 interactions	BPTF WBP11 WAPL SETD1B BRD2 UBTF TSPYL2 BAZ1B MLLT3 EIF3C PAF1 TRIP12 DNTTIP2 HP1BP3	2.40e-08	901	50	14	int:H3C1
Interaction	BRD3 interactions	BPTF BRD2 UBTF TSPYL2 BAZ1B FIP1L1 APP TRIP12 DNTTIP2 HP1BP3 EIF3CL	2.71e-08	494	50	11	int:BRD3
Interaction	H3C3 interactions	BPTF UBE2O WAPL BRD2 IPO7 BAZ2B UBTF BAZ1B TRIP12 DNTTIP2 HP1BP3	2.76e-08	495	50	11	int:H3C3
Interaction	CHD4 interactions	BPTF WBP11 UBE2O BRD2 UBTF NOM1 PPP1R12A BAZ1B FIP1L1 MLLT3 EIF3C PAF1 TRIP12 HP1BP3	3.98e-08	938	50	14	int:CHD4
Interaction	CBX3 interactions	RAD51AP1 UBE2O WAPL BRD2 UBTF PPP1R12A BAZ1B TRIP12 DNTTIP2 TFDP2 HP1BP3 NOL8	4.23e-08	646	50	12	int:CBX3
Interaction	SYT2 interactions	UBE2O ANKRD17 MLLT3 IFT46 FGFR1 APP PAF1	8.40e-08	150	50	7	int:SYT2
Interaction	SIRT7 interactions	BPTF ZC3H11A UBE2O IPO7 UBTF BAZ1B ANKRD17 HERC2 APP TRIP12 DNTTIP2 HP1BP3	1.96e-07	744	50	12	int:SIRT7
Interaction	APEX1 interactions	BPTF WAPL BRD2 UBTF PPP1R12A PLCB1 BAZ1B FGFR1 APP PAF1 TRIP12 DNTTIP2 TFDP2 HP1BP3 NOL8	2.53e-07	1271	50	15	int:APEX1
Interaction	POLR1G interactions	BPTF WBP11 URI1 BRD2 BAZ2B UBTF PAF1 TRIP12 DNTTIP2 NOL8	2.78e-07	489	50	10	int:POLR1G
Interaction	CENPA interactions	BPTF BRD2 IPO7 UBTF BAZ1B TRIP12 DNTTIP2 HP1BP3 NOL8	3.25e-07	377	50	9	int:CENPA
Interaction	CSNK2A1 interactions	UBE2O PTPRC BRD2 UBTF TSPYL2 FIP1L1 CASQ2 EIF3C APP PAF1 THOC5 HP1BP3 EIF3CL	3.93e-07	956	50	13	int:CSNK2A1
Interaction	SULF2 interactions	UBE2O BRD2 UBTF MLLT3 CASQ2 APP	4.80e-07	119	50	6	int:SULF2
Interaction	PLCD3 interactions	UBE2O BRD2 UBTF PPP1R12A MLLT3 CASQ2	5.30e-07	121	50	6	int:PLCD3
Interaction	RPS24 interactions	UBE2O UBTF NOM1 EIF3C HERC2 DNTTIP2 HP1BP3 EIF3CL NOL8 NGDN	5.70e-07	529	50	10	int:RPS24
Interaction	FGF3 interactions	TSPYL2 ANKRD17 FGFR1 DNTTIP2 NOL8	6.10e-07	66	50	5	int:FGF3
Interaction	RPL31 interactions	WBP11 UBE2O BRD2 IPO7 UBTF NOM1 APP PAF1 DNTTIP2 NOL8 NGDN	6.70e-07	680	50	11	int:RPL31
Interaction	NUPR1 interactions	WBP11 BRD2 UBTF PPP1R12A BAZ1B EIF3C PAF1 TRIP12 THOC5 DNTTIP2 HP1BP3	7.00e-07	683	50	11	int:NUPR1
Interaction	BRD2 interactions	BPTF UBE2O BRD2 UBTF TAF7L TSPYL2 BAZ1B DNTTIP2 HP1BP3	9.55e-07	429	50	9	int:BRD2
Interaction	CHAF1A interactions	BPTF BRD2 IPO7 PPP1R12A ANKRD17 EIF3C PAF1 TRIP12	1.17e-06	322	50	8	int:CHAF1A
Interaction	H2BC8 interactions	BPTF RAD51AP1 UBE2O WAPL BRD2 UBTF BAZ1B TRIP12 DNTTIP2 HP1BP3	1.23e-06	576	50	10	int:H2BC8
Interaction	OBSL1 interactions	WBP11 ZC3H11A BRD2 UBTF BAZ1B FIP1L1 CASQ2 HERC2 APP TRIP12 DNTTIP2 HP1BP3	1.51e-06	902	50	12	int:OBSL1
Interaction	MCRS1 interactions	WBP11 SETD1B BRD2 UBTF TSPYL2 TRIM44 CCDC136	1.75e-06	235	50	7	int:MCRS1
Interaction	DAXX interactions	UBE2O SETD1B BRD2 UBTF BAZ1B MLLT3 CASQ2 HP1BP3	2.31e-06	353	50	8	int:DAXX
Interaction	NUP43 interactions	BPTF SETD1B BAZ2B UBTF PPP1R12A TSPYL2 PAF1 TRIP12 DNTTIP2 HP1BP3	2.57e-06	625	50	10	int:NUP43
Interaction	ADARB1 interactions	BPTF WAPL EIF3C APP DNTTIP2 HP1BP3 EIF3CL NOL8 NGDN	2.80e-06	489	50	9	int:ADARB1
Interaction	MDK interactions	UBE2O BRD2 UBTF TMED8 MLLT3	3.03e-06	91	50	5	int:MDK
Interaction	RPS19 interactions	BPTF UBE2O NOM1 PPP1R12A BAZ1B FIP1L1 HERC2 APP HP1BP3 NGDN	3.13e-06	639	50	10	int:RPS19
Interaction	FGFBP1 interactions	UBTF NOM1 ANKRD17 TRIP12 HP1BP3 NOL8 NGDN	3.16e-06	257	50	7	int:FGFBP1
Interaction	ODAD3 interactions	IFT46 HERC2 TRIM44 CCDC136	3.50e-06	42	50	4	int:ODAD3
Interaction	NAA40 interactions	ZC3H11A UBE2O WAPL UBTF PPP1R12A BAZ1B ANKRD17 EIF3C PAF1 DNTTIP2 HP1BP3 NOL8	3.50e-06	978	50	12	int:NAA40
Interaction	HECTD1 interactions	BPTF ZC3H11A IPO7 UBTF NOM1 BAZ1B HERC2 TRIP12 DNTTIP2 HP1BP3 NOL8 NGDN	3.73e-06	984	50	12	int:HECTD1
Interaction	H1-1 interactions	SETD1B NOM1 PLCB1 CASQ2 APP PAF1 TRIP12 HP1BP3 NGDN	3.76e-06	507	50	9	int:H1-1
Interaction	AKAP17A interactions	ZC3H11A UBE2O BRD2 ANKRD17 HERC2	4.59e-06	99	50	5	int:AKAP17A
Interaction	DCPS interactions	IPO7 BAZ2B UBTF BAZ1B TRIP12 DNTTIP2 HP1BP3 NGDN	5.21e-06	394	50	8	int:DCPS
Interaction	C3orf49 interactions	BPTF UBTF TSPYL2	6.40e-06	15	50	3	int:C3orf49
Interaction	TOP1 interactions	ZC3H11A UBE2O BRD2 BAZ1B FIP1L1 HERC2 APP PAF1 THOC5 HP1BP3	6.66e-06	696	50	10	int:TOP1
Interaction	RNF2 interactions	IPO7 UBTF NOM1 BAZ1B FIP1L1 MLLT3 APP THOC5 TFDP2 HP1BP3 NGDN	6.95e-06	866	50	11	int:RNF2
Interaction	CEBPB interactions	BPTF WBP11 ZC3H11A BRD2 UBTF BAZ1B FIP1L1 MLLT3 EIF3C PAF1 THOC5 DNTTIP2 HP1BP3 NGDN	7.08e-06	1443	50	14	int:CEBPB
Interaction	UTP23 interactions	BRD2 UBTF BAZ1B ANKRD17 APP HP1BP3	7.53e-06	191	50	6	int:UTP23
Interaction	BCAR1 interactions	URI1 SETD1B IFT46 FGFR1 APP PAF1 DNTTIP2 EIF3CL NOL8	7.93e-06	556	50	9	int:BCAR1
Interaction	IFI16 interactions	IPO7 UBTF BAZ1B EIF3C APP PAF1 TRIP12 DNTTIP2 HP1BP3 NGDN	8.33e-06	714	50	10	int:IFI16
Interaction	SRPK2 interactions	WBP11 UBTF NOM1 TAF7L FIP1L1 APP TRIP12 HP1BP3 NOL8 NGDN	8.64e-06	717	50	10	int:SRPK2
Interaction	CSNK2A2 interactions	UBE2O PTPRC BRD2 TSPYL2 FIP1L1 CASQ2 EIF3C PAF1 STRIP1 EIF3CL	8.75e-06	718	50	10	int:CSNK2A2
Interaction	ABT1 interactions	UBE2O TSPYL2 APP TRIP12 CCDC136 DNTTIP2 NOL8 NGDN	8.75e-06	423	50	8	int:ABT1
Interaction	TSPYL1 interactions	BRD2 TSPYL2 APP TRIM44 CCDC136	9.98e-06	116	50	5	int:TSPYL1
Interaction	DUSP5 interactions	UBE2O AATK IPO7 ANKRD17	1.04e-05	55	50	4	int:DUSP5
Interaction	JPH3 interactions	BRD2 UBTF PPP1R12A TRIP12	1.04e-05	55	50	4	int:JPH3
Interaction	PNMA8A interactions	UBTF NOM1 ANKRD17 APP HP1BP3	1.28e-05	122	50	5	int:PNMA8A
Interaction	PARP1 interactions	BPTF RAD51AP1 UBE2O BRD2 UBTF BAZ1B FIP1L1 EIF3C PAF1 TRIP12 DNTTIP2 HP1BP3 NOL8	1.35e-05	1316	50	13	int:PARP1
Interaction	SPZ1 interactions	UBE2O HERC2 APP	1.85e-05	21	50	3	int:SPZ1
Interaction	SIRT6 interactions	WAPL SETD1B UBTF TSPYL2 FIP1L1 ANKRD17 HERC2 TRIP12 DNTTIP2	2.09e-05	628	50	9	int:SIRT6
Interaction	DNAJC8 interactions	WBP11 UBE2O BRD2 UBTF APP NOL8	2.16e-05	230	50	6	int:DNAJC8
Interaction	DDX23 interactions	WBP11 BRD2 UBTF FIP1L1 PAF1 THOC5 DNTTIP2 NOL8	2.18e-05	480	50	8	int:DDX23
Interaction	TULP3 interactions	WAPL PPP1R12A MLLT3 PAF1 TUB DNTTIP2 STRIP1	2.19e-05	346	50	7	int:TULP3
Interaction	USP53 interactions	BAZ1B ANKRD17 TRIP12 DNTTIP2 HP1BP3	2.32e-05	138	50	5	int:USP53
Interaction	ZFP91 interactions	UBE2O BRD2 NOM1 TSPYL2 CASQ2	2.32e-05	138	50	5	int:ZFP91
Interaction	POLR1E interactions	URI1 BRD2 BAZ2B UBTF NOM1 PAF1 NOL8	2.36e-05	350	50	7	int:POLR1E
Interaction	SUZ12 interactions	BPTF UBE2O BRD2 UBTF NOM1 FIP1L1 TRIP12 HP1BP3 NGDN	2.55e-05	644	50	9	int:SUZ12
Interaction	KANSL2 interactions	UBE2O SETD1B APP TRIM44	2.72e-05	70	50	4	int:KANSL2
Interaction	SRSF6 interactions	BPTF ZC3H11A UBE2O NOM1 APP HP1BP3 NOL8 NGDN	3.04e-05	503	50	8	int:SRSF6
Interaction	DHX40 interactions	UBE2O BRD2 UBTF NOM1 FIP1L1 NOL8	3.38e-05	249	50	6	int:DHX40
Interaction	RTF1 interactions	SETD1B BRD2 UBTF APP PAF1	3.46e-05	150	50	5	int:RTF1
Interaction	CIT interactions	ZSCAN29 BPTF IPO7 UBTF PPP1R12A BAZ1B FIP1L1 PAF1 TRIP12 THOC5 DNTTIP2 HP1BP3 EIF3CL	3.76e-05	1450	50	13	int:CIT
Interaction	PES1 interactions	UBE2O BRD2 UBTF MLLT3 CASQ2 APP	4.12e-05	258	50	6	int:PES1
Interaction	CT45A5 interactions	UBE2O BRD2 ANKRD17 MLLT3	4.18e-05	78	50	4	int:CT45A5
Interaction	TAF7L interactions	BRD2 TAF7L APP	4.51e-05	28	50	3	int:TAF7L
Interaction	H2BC21 interactions	ZSCAN29 BPTF BRD2 BAZ1B CASQ2 PAF1 TRIP12 DNTTIP2 HP1BP3	4.67e-05	696	50	9	int:H2BC21
Interaction	RPS6 interactions	UBE2O IPO7 UBTF NOM1 PAF1 DNTTIP2 HP1BP3 EIF3CL NOL8 NGDN	4.74e-05	874	50	10	int:RPS6
Interaction	ARL16 interactions	ZC3H11A NOM1 FIP1L1 TRIP12	5.33e-05	83	50	4	int:ARL16
Interaction	PHF7 interactions	PPP1R12A RNF34 APP	5.57e-05	30	50	3	int:PHF7
Interaction	COIL interactions	BRD2 BAZ2B UBTF TSPYL2 MLLT3 APP PAF1 CCDC136	5.87e-05	552	50	8	int:COIL
Interaction	TERF2IP interactions	BPTF WBP11 ZC3H11A WAPL UBTF PAF1 TRIP12 HP1BP3	5.87e-05	552	50	8	int:TERF2IP
Interaction	EIF3K interactions	UBE2O BRD2 EIF3C HERC2 EIF3CL	6.45e-05	171	50	5	int:EIF3K
Interaction	PPP1CC interactions	WBP11 URI1 UBE2O AATK PPP1R12A FIP1L1 APP PAF1 HP1BP3	7.35e-05	738	50	9	int:PPP1CC
Interaction	KCNE3 interactions	BRD2 PLCB1 RNF34 MLLT3 FGFR1 TRIP12	8.81e-05	296	50	6	int:KCNE3
Interaction	DNAJC9 interactions	UBE2O BRD2 UBTF BAZ1B DNTTIP2 HP1BP3	8.81e-05	296	50	6	int:DNAJC9
Interaction	TMA16 interactions	UBE2O TSPYL2 HERC2 APP	9.04e-05	95	50	4	int:TMA16
Interaction	EPB41L5 interactions	UBE2O BRD2 ANKRD17 MLLT3 CASQ2 APP	9.14e-05	298	50	6	int:EPB41L5
Interaction	EPB41L2 interactions	BPTF UBE2O PPP1R12A MLLT3 APP TRIP12	9.31e-05	299	50	6	int:EPB41L2
Interaction	NUSAP1 interactions	IPO7 PPP1R12A APP HP1BP3	1.19e-04	102	50	4	int:NUSAP1
Interaction	KIF21A interactions	BPTF FIP1L1 HP1BP3 NOL8	1.33e-04	105	50	4	int:KIF21A
Interaction	MYBBP1A interactions	UBE2O UBTF NOM1 BAZ1B APP TRIM44 HP1BP3	1.37e-04	463	50	7	int:MYBBP1A
Interaction	ABR interactions	FGFR1 HERC2 APP	1.43e-04	41	50	3	int:ABR
Interaction	ANKRD50 interactions	WBP11 PPP1R12A BAZ1B APP	1.49e-04	108	50	4	int:ANKRD50
Interaction	TAF1C interactions	UBE2O BRD2 UBTF TRIM44	1.49e-04	108	50	4	int:TAF1C
Interaction	TNIP1 interactions	AATK IPO7 UBTF NOM1 PPP1R12A FIP1L1 EIF3C DNTTIP2 HP1BP3 EIF3CL NGDN	1.57e-04	1217	50	11	int:TNIP1
Interaction	KLF8 interactions	BPTF BRD2 UBTF BAZ1B EIF3C APP	1.57e-04	329	50	6	int:KLF8
Interaction	FBL interactions	UBE2O IPO7 UBTF NOM1 BAZ1B ANKRD17 DNTTIP2 NOL8	1.62e-04	639	50	8	int:FBL
Interaction	EIF1 interactions	UBE2O EIF3C APP	1.65e-04	43	50	3	int:EIF1
Interaction	EED interactions	BPTF WBP11 ZC3H11A IPO7 BAZ2B NOM1 NRK BAZ1B HERC2 TRIP12 DMXL1 HP1BP3	1.66e-04	1445	50	12	int:EED
Interaction	PHYHD1 interactions	IPO7 APP	1.67e-04	8	50	2	int:PHYHD1
Interaction	CHTOP interactions	ZC3H11A UBE2O BRD2 APP THOC5	1.77e-04	212	50	5	int:CHTOP
Interaction	H3-5 interactions	UBE2O BAZ1B HERC2 HP1BP3	1.83e-04	114	50	4	int:H3-5
Interaction	RPL11 interactions	UBE2O WAPL NOM1 ANKRD17 APP TRIP12 HP1BP3 NGDN	1.86e-04	652	50	8	int:RPL11
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	WBP11 URI1 AATK NOM1 PPP1R12A	2.09e-05	181	34	5	694
GeneFamily	PHD finger proteins	BPTF BAZ2B BAZ1B	6.38e-04	90	34	3	88
GeneFamily	Zinc fingers CCCH-type	ZC3H11A ZC3H11B	1.96e-03	35	34	2	73
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	AATK FGFR1	2.56e-03	40	34	2	321
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	BPTF URI1 WAPL IPO7 BAZ2B PPP1R12A BAZ1B ANKRD17 APP TRIP12 TRIM44	4.93e-07	856	50	11	M4500
Coexpression	APRELIKOVA_BRCA1_TARGETS	FGFR1 EIF3C APP EIF3CL	2.33e-06	49	50	4	MM1178
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	RAD51AP1 WBP11 URI1 WAPL IPO7 UBTF PPP1R12A ANKRD17 DNTTIP2 DMXL1 NOL8	1.43e-05	1215	50	11	M41122
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	HIVEP3 BPTF URI1 ZC3H11A WAPL PTPRC UBTF PPP1R12A TSPYL2 BAZ1B TRIP12 DNTTIP2	1.78e-05	1492	50	12	M40023
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	BPTF WAPL IPO7 BAZ2B PPP1R12A ANKRD17 TRIP12	2.77e-05	466	50	7	M13522
Coexpression	GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_MAC_DN	SETD1B TTLL3 ANKRD17 TRIM44 TFDP2	3.85e-05	199	50	5	M5251
Coexpression	GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_DN	HIVEP3 ZC3H11A PTPRC TRIM44 STRIP1	3.94e-05	200	50	5	M7992
Coexpression	GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP	HIVEP3 URI1 PTPRC BRD2 NOL8	3.94e-05	200	50	5	M6539
Coexpression	GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP	SETD1B PTPRC TTLL3 BAZ2B TRIP12	3.94e-05	200	50	5	M9889
Coexpression	MARZEC_IL2_SIGNALING_DN	PTPRC PLCB1 TFDP2	4.46e-05	36	50	3	M13276
Coexpression	DIAZ_CHRONIC_MYELOGENOUS_LEUKEMIA_UP	WBP11 URI1 PTPRC IPO7 UBTF PPP1R12A MLLT3 EIF3C TRIP12 TFDP2 HP1BP3	5.24e-05	1399	50	11	M535
Coexpression	APRELIKOVA_BRCA1_TARGETS	FGFR1 EIF3C APP	1.06e-04	48	50	3	M1568
Coexpression	BASAKI_YBX1_TARGETS_DN	BPTF ZC3H11A TTLL3 BAZ2B TFDP2 DMXL1	1.07e-04	398	50	6	M14877
Coexpression	ONKEN_UVEAL_MELANOMA_UP	ZC3H11A PTPRC BAZ2B PPP1R12A BAZ1B HERC2 APP DMXL1	1.15e-04	790	50	8	M12490
Coexpression	GSE14415_INDUCED_VS_NATURAL_TREG_UP	BAZ2B PPP1R12A DNTTIP2 NOL8	1.88e-04	149	50	4	M2968
Coexpression	TABULA_MURIS_SENIS_LIVER_NK_CELL_AGEING	PTPRC BRD2 EIF3C HP1BP3 EIF3CL	2.19e-04	288	50	5	MM3751
Coexpression	GSE7596_AKT_TRANSD_VS_CTRL_CD4_TCONV_WITH_TGFB_UP	NOM1 BAZ1B TRIP12 NOL8	2.47e-04	160	50	4	M339
Coexpression	GERHOLD_ADIPOGENESIS_DN	UBTF EIF3C EIF3CL	2.51e-04	64	50	3	MM671
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	BPTF WAPL BAZ2B PPP1R12A BAZ1B	2.64e-04	300	50	5	M8702
Coexpression	GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_UP	BAZ2B EIF3C THOC5 NOL8	2.98e-04	168	50	4	M6874
Coexpression	GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_UP	URI1 UBTF HERC2 DMXL1	3.40e-04	174	50	4	M6296
Coexpression	LOPEZ_MBD_TARGETS	AATK IPO7 BAZ2B FIP1L1 MLLT3 FGFR1 APP EIF3CL	4.10e-04	953	50	8	M4120
Coexpression	PRC2_EZH2_UP.V1_UP	UBE2O AATK PLCB1 TUB	4.94e-04	192	50	4	M2739
Coexpression	GSE21927_UNTREATED_VS_GMCSF_IL6_TREATED_BONE_MARROW_UP	RAD51AP1 PPP1R12A TFDP2 HP1BP3	5.13e-04	194	50	4	M7554
Coexpression	GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_VA24NEG_NKTCELL_DN	SETD1B CASQ2 FGFR1 TFDP2	5.44e-04	197	50	4	M8303
Coexpression	GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN	PTPRC BAZ2B PPP1R12A TRIP12	5.44e-04	197	50	4	M4421
Coexpression	GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_UP	URI1 WAPL PTPRC MLLT3	5.44e-04	197	50	4	M6902
Coexpression	GSE15659_CD45RA_NEG_CD4_TCELL_VS_RESTING_TREG_DN	ZSCAN29 WAPL SETD1B TFDP2	5.54e-04	198	50	4	M3552
Coexpression	GSE360_DC_VS_MAC_DN	AATK TTLL3 TRIM44 NGDN	5.54e-04	198	50	4	M5173
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_DN	PTPRC BAZ2B RNF34 TRIP12	5.54e-04	198	50	4	M4424
Coexpression	GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_DN	URI1 WAPL BAZ1B HERC2	5.65e-04	199	50	4	M3204
Coexpression	GSE27786_CD8_TCELL_VS_NEUTROPHIL_UP	IFT46 TRIM44 NOL8 NGDN	5.65e-04	199	50	4	M4846
Coexpression	GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN	URI1 SETD1B TTLL3 CASQ2	5.65e-04	199	50	4	M7965
Coexpression	GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_DN	BRD2 BAZ2B TSPYL2 DMXL1	5.65e-04	199	50	4	M5214
Coexpression	GSE7548_NAIVE_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_UP	BPTF PLCB1 ANKRD17 PAF1	5.65e-04	199	50	4	M6839
Coexpression	GSE17721_LPS_VS_POLYIC_1H_BMDC_DN	URI1 UBTF RNF34 HP1BP3	5.65e-04	199	50	4	M3800
Coexpression	GSE21927_GMCSF_IL6_VS_GMCSF_GCSF_TREATED_BONE_MARROW_DN	IFT46 THOC5 DNTTIP2 NGDN	5.76e-04	200	50	4	M7609
Coexpression	HALLMARK_P53_PATHWAY	TSPYL2 APP DNTTIP2 NOL8	5.76e-04	200	50	4	M5939
Coexpression	GSE24814_STAT5_KO_VS_WT_PRE_BCELL_DN	BPTF PPP1R12A APP PAF1	5.76e-04	200	50	4	M8427
Coexpression	GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN	PPP1R12A MLLT3 CCDC136 TFDP2	5.76e-04	200	50	4	M7495
Coexpression	GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_6H_UP	ZC3H11A TTLL3 BAZ2B NGDN	5.76e-04	200	50	4	M6096
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_top-relative-expression-ranked_1000	WBP11 BRD2 BAZ2B UBTF NRK TAF7L CASQ2 FGFR1 EIF3C TRIP12 DNTTIP2 TFDP2 DMXL1	3.76e-08	822	50	13	gudmap_developingGonad_e14.5_ testes_1000
CoexpressionAtlas	DevelopingGonad_e16.5_testes_emap-8444_top-relative-expression-ranked_1000	BRD2 BAZ2B UBTF NRK TAF7L CASQ2 FGFR1 EIF3C TRIP12 TFDP2 DMXL1	2.48e-06	819	50	11	gudmap_developingGonad_e16.5_testes_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	RAD51AP1 WAPL IPO7 BAZ1B EIF3C DNTTIP2 DMXL1 NOL8	1.27e-05	469	50	8	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	RAD51AP1 WBP11 WAPL IPO7 MLLT3 EIF3C DNTTIP2 NOL8	3.13e-05	532	50	8	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	DevelopingGonad_e18.5_testes_emap-11164_top-relative-expression-ranked_1000	BRD2 BAZ2B UBTF NRK TAF7L CASQ2 FGFR1 EIF3C TRIP12	1.04e-04	814	50	9	gudmap_developingGonad_e18.5_testes_1000
CoexpressionAtlas	DevelopingGonad_P2_testes_emap-30171_top-relative-expression-ranked_1000	BRD2 BAZ2B UBTF NRK TAF7L CASQ2 FGFR1 EIF3C TFDP2	1.09e-04	819	50	9	gudmap_developingGonad_P2_testes_1000
ToppCell	Mild/Remission-B_naive-1\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ZC3H11A WAPL FGFR1 EIF3C EIF3CL	5.71e-07	143	50	5	bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAPL BAZ2B UBTF EIF3C HP1BP3	2.37e-06	191	50	5	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAPL BAZ2B UBTF EIF3C HP1BP3	2.37e-06	191	50	5	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAPL BAZ2B UBTF EIF3C HP1BP3	2.37e-06	191	50	5	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	Mild/Remission-B_naive-8\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	HIVEP3 BPTF PTPRC BAZ2B TFDP2	2.63e-06	195	50	5	0a3221e4d1fa31a35868bdda0f0cc873c233b407
ToppCell	PBMC-Control-cDC_3\|Control / Compartment, Disease Groups and Clusters	ZC3H11A PTPRC BRD2 ANKRD17 EIF3C	2.69e-06	196	50	5	09d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	BPTF ZC3H11A ANKRD17 TRIP12	1.75e-05	138	50	4	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	Mild-Lymphoid-NK-innate_T\|Mild / Condition, Lineage, Cell class and cell subclass	TSPYL2 PLCB1 ZC3H11B MLLT3	3.28e-05	162	50	4	bd218e41b2eadc3bba4c7ac3e34a014f6ad8b1bf
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_1\|COVID-19_Mild / Disease condition and Cell class	ZC3H11A WAPL EIF3C EIF3CL	3.52e-05	165	50	4	ef709c5d3231c65d351316e1e31b9c9eba721628
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_1\|Classical_Monocyte / Disease condition and Cell class	ZC3H11A WAPL EIF3C EIF3CL	3.78e-05	168	50	4	d50078614f7af74dc2aa4081c1708a5156ac51cf
ToppCell	COVID-19_Mild-CD4+_T_activated\|COVID-19_Mild / Disease condition and Cell class	ZC3H11A WAPL EIF3C EIF3CL	5.16e-05	182	50	4	877b6e611626628e709568747512f2827ebb2795
ToppCell	COVID-19_Mild-NK_activated\|COVID-19_Mild / Disease condition and Cell class	ZC3H11A WAPL EIF3C EIF3CL	5.27e-05	183	50	4	22bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 NRK PLCB1 APP	6.10e-05	190	50	4	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 NRK PLCB1 APP	6.10e-05	190	50	4	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	BPTF NOM1 BAZ1B HP1BP3	6.35e-05	192	50	4	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZC3H11A IPO7 FGFR1 APP	6.88e-05	196	50	4	151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	BPTF ZC3H11A BAZ2B TRIP12	7.29e-05	199	50	4	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	ZC3H11A PTPRC EIF3C EIF3CL	7.44e-05	200	50	4	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BPTF PTPRC TRIP12 TRIM44	7.44e-05	200	50	4	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	BAZ2B PLCB1 MLLT3 APP	7.44e-05	200	50	4	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	VE\|World / Condition, Cell_class and T cell subcluster	BPTF URI1 PTPRC HP1BP3	7.44e-05	200	50	4	8ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCell	PBMC-Severe-cDC_1\|Severe / Compartment, Disease Groups and Clusters	ZC3H11A FGFR1 EIF3C	1.04e-04	81	50	3	6d1e524f000b71c935359afc801a1d31f218fec8
Computational	Neighborhood of RBBP6	BPTF WAPL FIP1L1 NOL8	1.03e-04	70	38	4	GNF2_RBBP6
Drug	Pindolol [13523-86-9]; Down 200; 16.2uM; HL60; HG-U133A	HIVEP3 SETD1B UBTF PPP1R12A BAZ1B FGFR1	3.99e-06	197	49	6	1392_DN
Drug	Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; HL60; HG-U133A	HIVEP3 RAD51AP1 PPP1R12A ANKRD17 TFDP2 HP1BP3	4.23e-06	199	49	6	1994_UP
Drug	0179445-0000 [211246-22-9]; Down 200; 10uM; MCF7; HT_HG-U133A	BPTF WAPL SETD1B BAZ2B MLLT3	4.43e-05	182	49	5	3630_DN
Drug	colchicine; Up 200; 1uM; SKMEL5; HG-U133A	BPTF AATK SETD1B PPP1R12A FGFR1	5.44e-05	190	49	5	630_UP
Drug	Dantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A	BAZ2B PLCB1 FGFR1 APP HP1BP3	6.00e-05	194	49	5	3867_DN
Drug	Naloxone hydrochloride [357-08-4]; Down 200; 11uM; PC3; HG-U133A	RAD51AP1 BAZ2B PPP1R12A FGFR1 APP	6.00e-05	194	49	5	1924_DN
Drug	Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A	HIVEP3 PLCB1 BAZ1B APP TFDP2	6.15e-05	195	49	5	4368_DN
Drug	Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; HL60; HT_HG-U133A	HIVEP3 UBE2O TSPYL2 FIP1L1 PAF1	6.45e-05	197	49	5	1333_DN
Drug	Cinnarizine [298-57-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A	TSPYL2 FGFR1 THOC5 HP1BP3 NGDN	6.45e-05	197	49	5	7174_UP
Drug	Arcaine sulfate [14923-17-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A	HIVEP3 FGFR1 APP HP1BP3 NGDN	6.45e-05	197	49	5	4974_DN
Drug	Tolnaftate [2398-96-1]; Down 200; 13uM; MCF7; HT_HG-U133A	HIVEP3 UBE2O UBTF BAZ1B FGFR1	6.61e-05	198	49	5	4805_DN
Drug	DL-PPMP; Up 200; 2uM; MCF7; HT_HG-U133A_EA	BAZ2B FIP1L1 APP TRIM44 DNTTIP2	6.61e-05	198	49	5	1121_UP
Drug	Azathioprine [446-86-6]; Down 200; 14.4uM; HL60; HG-U133A	BPTF RAD51AP1 WAPL PPP1R12A APP	6.77e-05	199	49	5	2028_DN
Drug	beta-PCH	APP TRIM44	6.77e-05	6	49	2	CID000000728
Disease	Alzheimer's disease (implicated_via_orthology)	HIVEP3 PLCB1 APP	1.04e-04	57	47	3	DOID:10652 (implicated_via_orthology)
Disease	carnitine measurement	NRK PLCB1 STRIP1	2.45e-04	76	47	3	EFO_0010469
Disease	Infiltrating duct carcinoma of female breast	NRK FGFR1	5.12e-04	21	47	2	C3165106
Disease	Alzheimer's disease (is_marker_for)	BPTF PLCB1 FGFR1 APP	7.47e-04	257	47	4	DOID:10652 (is_marker_for)
Disease	body fat percentage	HIVEP3 BPTF UBTF ZC3H11B TRIP12	1.05e-03	488	47	5	EFO_0007800
Disease	triacylglycerol 52:5 measurement	PLCB1 MLLT3	1.43e-03	35	47	2	EFO_0010417
Disease	Neoplasm of uncertain or unknown behavior of breast	FGFR1 HERC2	1.96e-03	41	47	2	C0496956
Disease	Breast adenocarcinoma	FGFR1 HERC2	1.96e-03	41	47	2	C0858252
Disease	left ventricular systolic function measurement	TUB CCDC136	2.25e-03	44	47	2	EFO_0008206
Disease	Endogenous depression	FGFR1 APP	2.46e-03	46	47	2	C0011573
Disease	major depressive episode	SETD1B BAZ2B	2.56e-03	47	47	2	EFO_0007634
Disease	congenital left-sided heart lesions	HIVEP3 TFDP2	2.67e-03	48	47	2	EFO_0005938
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	HIVEP3 BPTF UBTF TRIP12	2.67e-03	364	47	4	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	total cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement	SETD1B ZC3H11B	2.78e-03	49	47	2	EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612

Protein segments in the cluster

Peptide	Gene	Start	Entry
EESDNVDSADAEEDD	APP	191	P05067
SEDSEDDESDEEEEE	BAZ1B	1251	Q9UIG0
EDDEDDESDDSQSES	BAZ2B	621	Q9UIF8
SEEEDDDDKDQDESD	BAZ2B	646	Q9UIF8
DSDYDDDDDDDSDDQ	BAZ2B	1296	Q9UIF8
HSDDNEEESDEVEDN	MLLT3	411	P42568
TSSNNSEEEEDDDDE	ANKRD17	111	O75179
DAEETQDSEDDEEDE	BPTF	151	Q12830
DSEESLGSDDDDNDD	DMXL1	2451	Q9Y485
SRDEDEDEDESSEED	HP1BP3	431	Q5SSJ5
EDEDESSEEDSEDEE	HP1BP3	436	Q5SSJ5
SEDDSDFCESEDNDE	RAD51AP1	206	Q96B01
AADDSSDDSDNEDVD	HERC2	4806	O95714
EHENDSDDDDEAEDD	IPO7	881	O95373
TEDDSDSDSDDDEDD	FIP1L1	81	Q6UN15
DSSDDDESDSEDDSN	NOL8	836	Q76FK4
SDADSEDDADSDDED	PAF1	456	Q8N7H5
DDEDEDSEDSEDDED	EIF3C	216	Q99613
DDEDEDSEDSEDDED	EIF3CL	216	B5ME19
ENEDDDDDDDDSSET	IFT46	31	Q9NQC8
DDDDDDSSETDSDSD	IFT46	36	Q9NQC8
DSSETDSDSDDDDEE	IFT46	41	Q9NQC8
EDDDDDDDSSSEEKE	FGFR1	126	P11362
NTEDDDEDDDDDDNS	CASQ2	371	O14958
DEDDDDDDNSDEEDN	CASQ2	376	O14958
DDDNSDEEDNDDSDD	CASQ2	381	O14958
DGDDDDESNDTFEDT	NRK	931	Q7Z2Y5
SDSRSNNDDDEDEDD	TAF7L	326	Q5H9L4
ESEDESDEESEEDSE	TRIM44	116	Q96DX7
YHSDDDDDDDDDDDD	URI1	296	O94763
EEEDSEDSDESDEEL	AATK	1161	Q6ZMQ8
DDSREEEEENDDDNS	STRIP1	376	Q5VSL9
DDDDDSDDRDESEND	SETD1B	1106	Q9UPS6
AEAQSEDDDEDTEEE	NOM1	276	Q5C9Z4
NDEDEEDDEEDSSSP	TFDP2	431	Q14188
DEEEEESESSDSEEE	BRD2	501	P25440
EEDSEEEEDDADSSL	CCDC136	1091	Q96JN2
DSSDHDENEDEFSDE	DNTTIP2	531	Q5QJE6
SDNEADEASDDEDND	TSPYL2	561	Q9H2G4
LSSEDEEEDEAEDDQ	NGDN	141	Q8NEJ9
ITSANTEDDDDDDDE	RNF34	216	Q969K3
DDDEDDDDQFSEEGD	ZC3H11A	161	O75152
AEQDADDEAADDTDD	UBE2O	476	Q9C0C9
EDSDSDSDLDEDEDE	HIVEP3	1851	Q5T1R4
DDLSESEDDEDDDCQ	WAPL	456	Q7Z5K2
DSDTTEDEDEDEDEE	TTLL3	66	Q9Y4R7
EADTESDDDDDDDDC	PLCB1	506	Q9NQ66
DDDEDDDDQFSEEGD	ZC3H11B	161	A0A1B0GTU1
EFSEDDDEDDSDDSE	WBP11	351	Q9Y2W2
EATEEDSDDDEEDTE	ZSCAN29	531	Q8IWY8
DSQDDESDSDAEEEQ	THOC5	306	Q13769
DEEEEDDENGDSSED	UBTF	691	P17480
DDDEDEDNESEGSSS	UBTF	736	P17480
REDDEDSDDDGSDEE	TRIP12	1311	Q14669
ESEHDSDESSDDDSD	PTPRC	996	P08575
FDEDEEDEEENSSSS	TUB	196	P50607
SDSSDDEDEEEEEEE	TMED8	236	Q6PL24
SSEEDEEDDSESEAE	PPP1R12A	356	O14974