Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	EGF_3	SSPOP LDLR FBN1 TENM1 LRP6 ASTN2 FBN3 NOTCH2 OTOG	7.94e-05	235	142	9	PS50026
Domain	C8	SSPOP MUC5AC OTOG	9.00e-05	12	142	3	PF08742
Domain	TIL	SSPOP MUC5AC OTOG	9.00e-05	12	142	3	PF01826
Domain	Unchr_dom_Cys-rich	SSPOP MUC5AC OTOG	1.16e-04	13	142	3	IPR014853
Domain	C8	SSPOP MUC5AC OTOG	1.16e-04	13	142	3	SM00832
Domain	TSP_1	ADAMTS3 ADGRB2 ADAMTSL3 SSPOP ADAMTS18	1.17e-04	63	142	5	PF00090
Domain	TSP1	ADAMTS3 ADGRB2 ADAMTSL3 SSPOP ADAMTS18	1.36e-04	65	142	5	SM00209
Domain	TSP1_rpt	ADAMTS3 ADGRB2 ADAMTSL3 SSPOP ADAMTS18	1.36e-04	65	142	5	IPR000884
Domain	TSP1	ADAMTS3 ADGRB2 ADAMTSL3 SSPOP ADAMTS18	1.36e-04	65	142	5	PS50092
Domain	TIL_dom	SSPOP MUC5AC OTOG	1.47e-04	14	142	3	IPR002919
Domain	EGF_1	LAMA1 SSPOP LDLR FBN1 TENM1 LRP6 ASTN2 FBN3 NOTCH2	1.48e-04	255	142	9	PS00022
Domain	FBN	FBN1 FBN3	1.71e-04	3	142	2	IPR011398
Domain	EGF_2	LAMA1 SSPOP LDLR FBN1 TENM1 LRP6 ASTN2 FBN3 NOTCH2	1.97e-04	265	142	9	PS01186
Domain	Post-SET_dom	NSD1 NSD3 KMT2D	2.24e-04	16	142	3	IPR003616
Domain	PostSET	NSD1 NSD3 KMT2D	2.24e-04	16	142	3	SM00508
Domain	VWF_type-D	SSPOP MUC5AC OTOG	2.24e-04	16	142	3	IPR001846
Domain	VWFD	SSPOP MUC5AC OTOG	2.24e-04	16	142	3	PS51233
Domain	VWD	SSPOP MUC5AC OTOG	2.24e-04	16	142	3	SM00216
Domain	POST_SET	NSD1 NSD3 KMT2D	2.24e-04	16	142	3	PS50868
Domain	VWD	SSPOP MUC5AC OTOG	2.24e-04	16	142	3	PF00094
Domain	LDLR_class-A_CS	DGCR2 SSPOP LDLR LRP6	2.37e-04	40	142	4	IPR023415
Domain	VWF_dom	DGCR2 SSPOP MUC5AC OTOG	2.86e-04	42	142	4	IPR001007
Domain	Ldl_recept_a	DGCR2 SSPOP LDLR LRP6	3.75e-04	45	142	4	PF00057
Domain	VWC_out	SSPOP MUC5AC OTOG	3.81e-04	19	142	3	SM00215
Domain	PLAC	ADAMTS3 ADAMTSL3 ADAMTS18	3.81e-04	19	142	3	PS50900
Domain	PLAC	ADAMTS3 ADAMTSL3 ADAMTS18	3.81e-04	19	142	3	IPR010909
Domain	SET	NSD1 NSD3 KMT2D PRDM15	4.08e-04	46	142	4	SM00317
Domain	-	DGCR2 SSPOP LDLR LRP6	4.08e-04	46	142	4	4.10.400.10
Domain	LDLRA_1	DGCR2 SSPOP LDLR LRP6	4.81e-04	48	142	4	PS01209
Domain	LDrepeatLR_classA_rpt	DGCR2 SSPOP LDLR LRP6	5.20e-04	49	142	4	IPR002172
Domain	LDLa	DGCR2 SSPOP LDLR LRP6	5.20e-04	49	142	4	SM00192
Domain	LDLRA_2	DGCR2 SSPOP LDLR LRP6	5.20e-04	49	142	4	PS50068
Domain	SET_dom	NSD1 NSD3 KMT2D PRDM15	5.62e-04	50	142	4	IPR001214
Domain	SET	NSD1 NSD3 KMT2D PRDM15	5.62e-04	50	142	4	PS50280
Domain	NUT	NUTM2A NUTM2B	5.65e-04	5	142	2	IPR024310
Domain	AWS	NSD1 NSD3	5.65e-04	5	142	2	SM00570
Domain	NUT_N	NUTM2A NUTM2B	5.65e-04	5	142	2	IPR024309
Domain	NUT	NUTM2A NUTM2B	5.65e-04	5	142	2	PF12881
Domain	AWS	NSD1 NSD3	5.65e-04	5	142	2	PS51215
Domain	AWS_dom	NSD1 NSD3	5.65e-04	5	142	2	IPR006560
Domain	EGF-like_dom	LAMA1 LDLR FBN1 TENM1 LRP6 FBN3 NOTCH2 OTOG	6.45e-04	249	142	8	IPR000742
Domain	Peptidase_M12B_ADAM-TS	ADAMTS3 ADAMTSL3 ADAMTS18	7.75e-04	24	142	3	IPR013273
Domain	GDNF	GAS1 GFRA3	8.44e-04	6	142	2	PF02351
Domain	GDNF	GAS1 GFRA3	8.44e-04	6	142	2	SM00907
Domain	GDNF/GAS1	GAS1 GFRA3	8.44e-04	6	142	2	IPR016017
Domain	Cys_knot_C	SSPOP MUC5AC OTOG	8.75e-04	25	142	3	IPR006207
Domain	CTCK_2	SSPOP MUC5AC OTOG	8.75e-04	25	142	3	PS01225
Domain	TB	FBN1 FBN3	1.18e-03	7	142	2	PF00683
Domain	IPK	ITPKA ITPKB	1.18e-03	7	142	2	PF03770
Domain	IPK	ITPKA ITPKB	1.18e-03	7	142	2	IPR005522
Domain	Growth_fac_rcpt_	LAMA1 LDLR FBN1 ELAPOR1 FBN3 NOTCH2	1.24e-03	156	142	6	IPR009030
Domain	-	FBN1 FBN3	1.56e-03	8	142	2	3.90.290.10
Domain	-	ZNF185 LMO3 LMO1 LMX1B	1.99e-03	70	142	4	2.10.110.10
Domain	TB_dom	FBN1 FBN3	2.00e-03	9	142	2	IPR017878
Domain	TB	FBN1 FBN3	2.00e-03	9	142	2	PS51364
Domain	LIM	ZNF185 LMO3 LMO1 LMX1B	2.10e-03	71	142	4	SM00132
Domain	Znf_LIM	ZNF185 LMO3 LMO1 LMX1B	2.10e-03	71	142	4	IPR001781
Domain	LIM_DOMAIN_1	ZNF185 LMO3 LMO1 LMX1B	2.10e-03	71	142	4	PS00478
Domain	LIM_DOMAIN_2	ZNF185 LMO3 LMO1 LMX1B	2.10e-03	71	142	4	PS50023
Domain	EGF	LAMA1 LDLR FBN1 TENM1 LRP6 FBN3 NOTCH2	2.16e-03	235	142	7	SM00181
Domain	RING	TRAF2 NSD1 NSD3 KMT2D LTN1 MIB1 NFX1 RNF138	2.34e-03	305	142	8	SM00184
Domain	VWFC_1	DGCR2 SSPOP MUC5AC	2.56e-03	36	142	3	PS01208
Domain	VWFC_2	DGCR2 SSPOP MUC5AC	2.99e-03	38	142	3	PS50184
Domain	VWC	DGCR2 SSPOP MUC5AC	2.99e-03	38	142	3	SM00214
Domain	Znf_PHD-finger	NSD1 NSD3 KMT2D NFX1	3.10e-03	79	142	4	IPR019787
Domain	Pep_M12B_propep	ADAMTS3 ADAM7 ADAMTS18	3.22e-03	39	142	3	PF01562
Domain	Peptidase_M12B_N	ADAMTS3 ADAM7 ADAMTS18	3.22e-03	39	142	3	IPR002870
Domain	-	LDLR TENM1 LRP6	3.22e-03	39	142	3	2.120.10.30
Domain	Znf_C2H2	SORBS2 RREB1 ZXDA ZNF786 ZBTB14 ZNF440 ZNF23 GZF1 ZNF608 EEA1 PRDM15 RNF138 ZNF345 ZNF124	3.33e-03	805	142	14	IPR007087
Domain	DISINTEGRIN_1	ADAMTS3 ADAM7 ADAMTS18	3.46e-03	40	142	3	PS00427
Domain	Reprolysin	ADAMTS3 ADAM7 ADAMTS18	3.46e-03	40	142	3	PF01421
Domain	ADAM_MEPRO	ADAMTS3 ADAM7 ADAMTS18	3.46e-03	40	142	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS3 ADAM7 ADAMTS18	3.46e-03	40	142	3	PS50214
Domain	Peptidase_M12B	ADAMTS3 ADAM7 ADAMTS18	3.46e-03	40	142	3	IPR001590
Domain	Znf_RING	TRAF2 NSD1 NSD3 KMT2D LTN1 MIB1 NFX1 RNF138	3.52e-03	326	142	8	IPR001841
Domain	SET	NSD1 NSD3 KMT2D	3.71e-03	41	142	3	PF00856
Domain	Disintegrin_dom	ADAMTS3 ADAM7 ADAMTS18	3.71e-03	41	142	3	IPR001762
Domain	EGF-like_CS	LAMA1 LDLR FBN1 TENM1 LRP6 FBN3 NOTCH2	3.86e-03	261	142	7	IPR013032
Domain	EGF_CA	LDLR FBN1 FBN3 NOTCH2	4.20e-03	86	142	4	PF07645
Domain	Rho_GTPase_activation_prot	ARHGAP26 OCRL ARHGAP35 PLXNA4	4.56e-03	88	142	4	IPR008936
Domain	PLAC	ADAMTSL3 ADAMTS18	4.92e-03	14	142	2	PF08686
Domain	Ldl_recept_b	LDLR LRP6	4.92e-03	14	142	2	PF00058
Domain	LDLRB	LDLR LRP6	4.92e-03	14	142	2	PS51120
Domain	6-blade_b-propeller_TolB-like	LDLR TENM1 LRP6	5.14e-03	46	142	3	IPR011042
Domain	LY	LDLR LRP6	5.65e-03	15	142	2	SM00135
Domain	LDLR_classB_rpt	LDLR LRP6	5.65e-03	15	142	2	IPR000033
Domain	EGF_Ca-bd_CS	LDLR FBN1 FBN3 NOTCH2	6.43e-03	97	142	4	IPR018097
Domain	EGF_CA	LDLR FBN1 FBN3 NOTCH2	6.90e-03	99	142	4	PS01187
Domain	ASX_HYDROXYL	LDLR FBN1 FBN3 NOTCH2	7.15e-03	100	142	4	PS00010
Domain	-	TRAF2 USP45 NSD1 NSD3 KMT2D LTN1 MIB1 EEA1 RNF138	7.44e-03	449	142	9	3.30.40.10
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS3 ADAMTSL3 SSPOP ADAMTS18 MUC5AC NOTCH2	9.97e-06	68	103	6	M27303
Pathway	REACTOME_DISEASES_OF_METABOLISM	ABCA3 ADAMTS3 ADAMTSL3 SSPOP GCLM ADAMTS18 KHK MUC5AC NOTCH2	8.84e-05	250	103	9	M27554
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS3 ADAMTSL3 SSPOP ADAMTS18	1.82e-04	39	103	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS3 ADAMTSL3 SSPOP ADAMTS18	1.82e-04	39	103	4	MM15165
Pathway	REACTOME_RHOJ_GTPASE_CYCLE	ARHGAP26 OCRL ARHGAP35	1.98e-04	16	103	3	MM15605
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DGCR2 SZT2 ARHGAP26 WDR70 ADGRB2 NSD1 TSC2 RHOT2 ARHGAP35 DYSF ZZEF1 PRAG1 LDLR NSD3 KMT2D ZBED4 LMX1B NFX1 FLCN TIMM22 NOTCH2	1.05e-08	1105	148	21	35748872
Pubmed	MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.	NANOG LDLR LRP6 EEA1	1.78e-06	21	148	4	21337463
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	VRK3 NCKIPSD PEPD SEC31A ARHGAP35 LDLR NSD3 FABP5 SHCBP1 MIB1 SSH2 PRDM15 OTOG	8.55e-06	689	148	13	36543142
Pubmed	Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass.	NANOG KIF4A KIF4B	8.87e-06	10	148	3	29101321
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS3 ADGRB2 ADAMTSL3 SSPOP ADAMTS18	1.77e-05	75	148	5	20637190
Pubmed	KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.	KIF4A KIF4B	1.80e-05	2	148	2	36482480
Pubmed	The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential.	KIF4A KIF4B	1.80e-05	2	148	2	30081192
Pubmed	Localization of the genes for human inositol 1,4,5-trisphosphate 3-kinase A (ITPKA) and B (ITPKB) to chromosome regions 15q14-q21 and 1q41-q43, respectively, by in situ hybridization.	ITPKA ITPKB	1.80e-05	2	148	2	1330886
Pubmed	Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.	KIF4A KIF4B	1.80e-05	2	148	2	31067151
Pubmed	Cellular motor protein KIF-4 associates with retroviral Gag.	KIF4A KIF4B	1.80e-05	2	148	2	10559369
Pubmed	KIF4 regulates midzone length during cytokinesis.	KIF4A KIF4B	1.80e-05	2	148	2	21565503
Pubmed	A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.	KIF4A KIF4B	1.80e-05	2	148	2	7929562
Pubmed	Molecular cloning and expression of a new putative inositol 1,4,5-trisphosphate 3-kinase isoenzyme.	ITPKA ITPKB	1.80e-05	2	148	2	1654894
Pubmed	The combined hyperlipidemia caused by impaired Wnt-LRP6 signaling is reversed by Wnt3a rescue.	LDLR LRP6	1.80e-05	2	148	2	24506864
Pubmed	Microarray analysis indicates an important role for FABP5 and putative novel FABPs on a Western-type diet.	LDLR FABP5	1.80e-05	2	148	2	16885566
Pubmed	Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells.	KIF4A KIF4B	1.80e-05	2	148	2	31486502
Pubmed	Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization.	KIF4A KIF4B	1.80e-05	2	148	2	10773663
Pubmed	LRP6 protein regulates low density lipoprotein (LDL) receptor-mediated LDL uptake.	LDLR LRP6	1.80e-05	2	148	2	22128165
Pubmed	Missense Pathogenic variants in KIF4A Affect Dental Morphogenesis Resulting in X-linked Taurodontism, Microdontia and Dens-Invaginatus.	KIF4A KIF4B	1.80e-05	2	148	2	31616463
Pubmed	Kif4 regulates the expression of VEGFR1 through the PI3K/Akt signaling pathway in RAW264.7 monocytes/macrophages.	KIF4A KIF4B	1.80e-05	2	148	2	28350061
Pubmed	Cloning and expression in Escherichia coli of a rat brain cDNA encoding a Ca2+/calmodulin-sensitive inositol 1,4,5-trisphosphate 3-kinase.	ITPKA ITPKB	1.80e-05	2	148	2	2176078
Pubmed	Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients.	FBN1 FBN3	1.80e-05	2	148	2	15221638
Pubmed	Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts.	KIF4A KIF4B	1.80e-05	2	148	2	24658398
Pubmed	Regulation of MEF2 transcriptional activity by calcineurin/mAKAP complexes.	AKAP6 PPP3CA	1.80e-05	2	148	2	23261540
Pubmed	Structural basis for the ATP-induced isomerization of kinesin.	KIF4A KIF4B	1.80e-05	2	148	2	23500491
Pubmed	Impaired LRP6-TCF7L2 Activity Enhances Smooth Muscle Cell Plasticity and Causes Coronary Artery Disease.	LDLR LRP6	1.80e-05	2	148	2	26489464
Pubmed	Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein.	KIF4A KIF4B	1.80e-05	2	148	2	9658142
Pubmed	Knockdown of Slingshot 2 (SSH2) serine phosphatase induces Caspase3 activation in human carcinoma cell lines with the loss of the Birt-Hogg-Dubé tumour suppressor gene (FLCN).	FLCN SSH2	1.80e-05	2	148	2	23416984
Pubmed	ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.	ADAMTS3 LAMA1 ADAMTS18	4.06e-05	16	148	3	30579834
Pubmed	Retina-driven dephosphorylation of the NR2A subunit correlates with faster NMDA receptor kinetics at developing retinocollicular synapses.	GRIN2A PPP3CA	5.38e-05	3	148	2	15590926
Pubmed	The NSD family of protein methyltransferases in human cancer.	NSD1 NSD3	5.38e-05	3	148	2	25942451
Pubmed	Vascular smooth muscle LRP6 limits arteriosclerotic calcification in diabetic LDLR-/- mice by restraining noncanonical Wnt signals.	LDLR LRP6	5.38e-05	3	148	2	26034040
Pubmed	Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas.	KMT2D NOTCH2	5.38e-05	3	148	2	27566587
Pubmed	Tumor formation via loss of a molecular motor protein.	KIF4A KIF4B	5.38e-05	3	148	2	16890532
Pubmed	KIF4 mediates anterograde translocation and positioning of ribosomal constituents to axons.	KIF4A KIF4B	5.38e-05	3	148	2	19158085
Pubmed	Identification of the human homologue of mouse KIF4, a kinesin superfamily motor protein.	KIF4A KIF4B	5.38e-05	3	148	2	10978527
Pubmed	Null mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in mice.	LMO3 LMO1	5.38e-05	3	148	2	14966285
Pubmed	The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.	NUTM2E NUTM2B	5.38e-05	3	148	2	26542179
Pubmed	The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.	NUTM2A NUTM2B	5.38e-05	3	148	2	22456610
Pubmed	Macrophage Mal1 deficiency suppresses atherosclerosis in low-density lipoprotein receptor-null mice by activating peroxisome proliferator-activated receptor-γ-regulated genes.	LDLR FABP5	5.38e-05	3	148	2	21474828
Pubmed	Expression of LIM protein genes Lmo1, Lmo2, and Lmo3 in adult mouse hippocampus and other forebrain regions: differential regulation by seizure activity.	LMO3 LMO1	5.38e-05	3	148	2	9204936
Pubmed	Critical role of cytosolic phospholipase A2{alpha} in bronchial mucus hypersecretion in CFTR-deficient mice.	PLA2G4A MUC5AC	5.38e-05	3	148	2	20413542
Pubmed	The role of NSD1, NSD2, and NSD3 histone methyltransferases in solid tumors.	NSD1 NSD3	5.38e-05	3	148	2	35532818
Pubmed	KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity.	KIF4A KIF4B	5.38e-05	3	148	2	16630823
Pubmed	The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells.	ITPKA ITPKB	5.38e-05	3	148	2	12747803
Pubmed	CircKIF4A enhances osteosarcoma proliferation and metastasis by sponging MiR-515-5p and upregulating SLC7A11.	KIF4A KIF4B	5.38e-05	3	148	2	35579738
Pubmed	Identification of phosphorylation sites of human 85-kDa cytosolic phospholipase A2 expressed in insect cells and present in human monocytes.	MKNK1 PLA2G4A	5.38e-05	3	148	2	8636128
Pubmed	ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.	LAMA1 FBN1 ADAMTS18	5.88e-05	18	148	3	39040056
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	SORBS2 GGA2 PINLYP DBNDD2 FAAP20 NSD1 PRR22 CHRNB4 FABP5 ZNF608 GCLM SHCBP1 LTN1 TENM1 PRDM15 FBN3	6.47e-05	1215	148	16	15146197
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	RCE1 OR5B2 NEXMIF LAMA1 TSC2 ZZEF1 SSPOP CHRNB4 ZBED4 PLXNA4 CHD6 FBN3	7.84e-05	736	148	12	29676528
Pubmed	A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.	AKAP6 PEPD RREB1 LMO1	9.07e-05	55	148	4	22581228
Pubmed	Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.	FBN1 FBN3	1.07e-04	4	148	2	25034023
Pubmed	Pathogenicity of lupus anti-ribosomal P antibodies: role of cross-reacting neuronal surface P antigen in glutamatergic transmission and plasticity in a mouse model.	GRIN2A ZZEF1	1.07e-04	4	148	2	25709106
Pubmed	Tight junction-based epithelial microenvironment and cell proliferation.	CLDN22 CLDN24	1.07e-04	4	148	2	19029935
Pubmed	Kinesin KIF4 regulates intracellular trafficking and stability of the human immunodeficiency virus type 1 Gag polyprotein.	KIF4A KIF4B	1.07e-04	4	148	2	18684836
Pubmed	Kif4 Is Essential for Mouse Oocyte Meiosis.	KIF4A KIF4B	1.07e-04	4	148	2	28125646
Pubmed	LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export.	LDLR PLA2G4A	1.07e-04	4	148	2	19718435
Pubmed	Histone and DNA binding ability studies of the NSD subfamily of PWWP domains.	NSD1 NSD3	1.07e-04	4	148	2	34271259
Pubmed	A GTPase-activating protein-binding protein (G3BP1)/antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells.	LDLR LRP6	1.07e-04	4	148	2	29626090
Pubmed	LIM-domain-only proteins: multifunctional nuclear transcription coregulators that interacts with diverse proteins.	LMO3 LMO1	1.07e-04	4	148	2	24379077
Pubmed	TCF7L2 (Transcription Factor 7-Like 2) Regulation of GATA6 (GATA-Binding Protein 6)-Dependent and -Independent Vascular Smooth Muscle Cell Plasticity and Intimal Hyperplasia.	LDLR LRP6	1.07e-04	4	148	2	30567484
Pubmed	The absence of expression of the three isoenzymes of the inositol 1,4,5-trisphosphate 3-kinase does not prevent the formation of inositol pentakisphosphate and hexakisphosphate in mouse embryonic fibroblasts.	ITPKA ITPKB	1.07e-04	4	148	2	17355905
Pubmed	Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.	LAMA1 GRIN2A TENM1	1.10e-04	22	148	3	35245678
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	TRAF2 SORBS2 NCKIPSD ADGRB2 TSC2 GRIN2A SEC31A FBN1 CEP89 NOTCH2	1.52e-04	560	148	10	21653829
Pubmed	In vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1 and NSD3/WHSC1L.	NSD1 NSD3	1.78e-04	5	148	2	25494638
Pubmed	Genetic interaction between Wnt7a and Lrp6 during patterning of dorsal and posterior structures of the mouse limb.	LMX1B LRP6	1.78e-04	5	148	2	15880584
Pubmed	Serine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinases.	MKNK1 PLA2G4A	1.78e-04	5	148	2	10978317
Pubmed	Systematic perturbations of SETD2, NSD1, NSD2, NSD3, and ASH1L reveal their distinct contributions to H3K36 methylation.	NSD1 NSD3	1.78e-04	5	148	2	39390582
Pubmed	Expression, purification, and regulation of two isoforms of the inositol 1,4,5-trisphosphate 3-kinase.	ITPKA ITPKB	1.78e-04	5	148	2	9374536
Pubmed	Identification of the phosphorylation sites of cytosolic phospholipase A2 in agonist-stimulated human platelets and HeLa cells.	MKNK1 PLA2G4A	1.78e-04	5	148	2	9468497
Pubmed	Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG.	GRIN2A ZZEF1	1.78e-04	5	148	2	33158444
Pubmed	Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia.	LDLR EEA1	1.78e-04	5	148	2	12746448
Pubmed	Adamts18 modulates the development of the aortic arch and common carotid artery.	LAMA1 FBN1 ADAMTS18	1.83e-04	26	148	3	34189436
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	RCE1 DGCR2 GAS1 LAMA1 KIF4A TSC2 ZZEF1 LDLR TMX1 FBN1 GLG1 LTN1 FLCN LRP6 NOTCH2	1.97e-04	1201	148	15	35696571
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	WDR70 PEPD WDR27 ANKMY1 ARHGAP35 SSPOP BRWD3 ZNF440 ITPKB MALT1 PPP3CA ZNF608 ASTN2 CHD6 H1-10-AS1 PRDM15 NOTCH2	2.11e-04	1489	148	17	28611215
Pubmed	The inhibitor of apoptosis protein fusion c-IAP2.MALT1 stimulates NF-kappaB activation independently of TRAF1 AND TRAF2.	TRAF2 MALT1	2.67e-04	6	148	2	16891304
Pubmed	The mouse kinome: discovery and comparative genomics of all mouse protein kinases.	PRAG1 PXK	2.67e-04	6	148	2	15289607
Pubmed	TRAF2-binding BIR1 domain of c-IAP2/MALT1 fusion protein is essential for activation of NF-kappaB.	TRAF2 MALT1	2.67e-04	6	148	2	19234489
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	VRK3 WDR70 NSD1 KIF4A RREB1 NSD3 FSIP2 CHD6 NOP2 PRDM15	2.92e-04	608	148	10	36089195
Pubmed	TBX1 is required for normal stria vascularis and semicircular canal development.	FBN1 RNF138 OTOG	3.11e-04	31	148	3	31550482
Pubmed	LncRNA PVT-1 promotes osteosarcoma cancer stem-like properties through direct interaction with TRIM28 and TSC2 ubiquitination.	TSC2 NOP2	3.72e-04	7	148	2	36348010
Pubmed	Genetic mapping in the mouse of Kif4, a gene encoding a kinesin-like motor protein.	KIF4A KIF4B	3.72e-04	7	148	2	9196009
Pubmed	Unusual chromatin status and organization of the inactive X chromosome in murine trophoblast giant cells.	KIF4A KIF4B	3.72e-04	7	148	2	23362347
Pubmed	Kinesin family in murine central nervous system.	KIF4A KIF4B	3.72e-04	7	148	2	1447303
Pubmed	Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition.	APAF1 GSDME	3.72e-04	7	148	2	33308446
Pubmed	Characterization of PXK as a protein involved in epidermal growth factor receptor trafficking.	PXK EEA1	3.72e-04	7	148	2	20086096
Pubmed	Parent stem cells can serve as niches for their daughter cells.	MIB1 NOTCH2	3.72e-04	7	148	2	26147083
Pubmed	The E3 ubiquitin ligase mind bomb-2 (MIB2) protein controls B-cell CLL/lymphoma 10 (BCL10)-dependent NF-κB activation.	MALT1 MIB1	3.72e-04	7	148	2	21896478
Pubmed	The DNA sequence of the human X chromosome.	NEXMIF KIF4A OCRL MORC4 ZXDA BRWD3 ASMT TENM1	3.72e-04	407	148	8	15772651
Pubmed	Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans.	SEC31A EEA1	4.95e-04	8	148	2	24239381
Pubmed	Identification of potential regulatory motifs in odorant receptor genes by analysis of promoter sequences.	OR9G4 OR1P1	4.95e-04	8	148	2	16902085
Pubmed	Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR-/- embryos at 12.5 to 14.5 days of gestation.	LDLR LRP6	4.95e-04	8	148	2	15265030
Pubmed	Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases.	OCRL EEA1	4.95e-04	8	148	2	16902405
Pubmed	Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.	LAMA1 FBN1 ADAMTS18	5.28e-04	37	148	3	34323105
Pubmed	The genetic architecture of economic and political preferences.	AKAP6 PLXNA4 ASTN2	5.28e-04	37	148	3	22566634
Pubmed	Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3.	NANOG FLCN	6.35e-04	9	148	2	23582324
Pubmed	Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation.	TRAF2 MALT1	6.35e-04	9	148	2	17462996
Pubmed	Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.	LAMA1 FBN1	7.91e-04	10	148	2	9415455
Pubmed	Syntaxin 3 and Munc-18-2 in epithelial cells during kidney development.	LAMA1 STXBP2	7.91e-04	10	148	2	10469351
Pubmed	Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal.	NANOG LAMA1	7.91e-04	10	148	2	20123909
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	NSD1 NSD3 KMT2D	7.94e-04	34	97	3	487
GeneFamily	PHD finger proteins	NSD1 NSD3 KMT2D NFX1	1.40e-03	90	97	4	88
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	RREB1 ZXDA ZNF786 ZBTB14 ZNF440 ZNF23 GZF1 ZNF608 PRDM15 ZNF345 ZNF124	1.60e-03	718	97	11	28
GeneFamily	Low density lipoprotein receptors	LDLR LRP6	2.14e-03	13	97	2	634
GeneFamily	WD repeat domain containing	WDR70 APAF1 WDR27 SEC31A BRWD3 DCAF8L1	2.88e-03	262	97	6	362
GeneFamily	X-linked mental retardation\|Angiotensin receptors	NEXMIF KIF4A BRWD3	2.89e-03	53	97	3	103
GeneFamily	LIM domain containing	ZNF185 LMO3 LMO1	3.92e-03	59	97	3	1218
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	ZZEF1 MIB1	4.12e-03	18	97	2	91
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS3 ADAMTS18	4.59e-03	19	97	2	50
ToppCell	Bronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TCEA3 ABCA3 OCRL PLXNA4 FLCN ASTN2 CAPN15	1.25e-07	116	148	7	b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A33 OCRL TMX1 PTCHD1 ZNF608 SV2B ELAPOR1 ANO7	1.79e-07	182	148	8	eb4be1c02b8b033d025e57b8b4cdbfaec4698054
ToppCell	facs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3AP1 GGA2 ARHGAP26 PXK ZNF608 CD38 HPX NOTCH2	2.20e-07	187	148	8	b51af2824e65734f333b1325117f4a2e88b17c23
ToppCell	facs-Spleen-nan-3m-Lymphocytic-B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3AP1 GGA2 ARHGAP26 PXK ZNF608 CD38 HPX NOTCH2	2.20e-07	187	148	8	3ca3954f45f167e98a230f2847f0582d74fcd32e
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SORBS2 NLRP7 ZNF23 ASMT SHCBP1 CD38 ASB2	2.17e-06	177	148	7	d2c1f46913ac00bbc0bb9320d5652edc01b34179
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SORBS2 NLRP7 ZNF23 ASMT SHCBP1 CD38 ASB2	2.17e-06	177	148	7	65e090aad0ffb737ce034e25bd5b12a0b1dd9684
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCEA3 LMO3 LDLR FABP5 BMP3 PTCHD1 ELAPOR1	3.98e-06	194	148	7	db06ae2dba45640da329a4d0d94973ac9dda7729
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCEA3 LMO3 LDLR FABP5 BMP3 PTCHD1 ELAPOR1	3.98e-06	194	148	7	d3f5cd6c40354bfe86348bb0e82697a939759625
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCEA3 LMO3 LDLR FABP5 BMP3 PTCHD1 ELAPOR1	3.98e-06	194	148	7	d4f4036b650a27312283fa8851f3975595cc2d3f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-epithelial_cell_of_lung\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCEA3 LMO3 LDLR FABP5 BMP3 PTCHD1 ELAPOR1	3.98e-06	194	148	7	4974c208e6ee37a51cd95a61d48b26c5de416992
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Smooth_Muscle-like_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	AKAP6 SLC25A33 ADAM7 GAS1 PTCHD1 ASB2	7.47e-06	140	148	6	5623a0a68403fc00166b7d13d13e184a718d9bdd
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor\|bone_marrow / Manually curated celltypes from each tissue	ST20 KIF4A OCRL FBN1 NT5DC2 SHCBP1	9.50e-06	146	148	6	035393166f3ad5ab95602a8ae11b7d0ee4b1d691
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ST20 OR8H1 PXK KMT2D LINC00471 H1-10-AS1	1.20e-05	152	148	6	0652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRIN2A ADAMTSL3 PXK PPP3CA ADAMTS18 FBN3	1.90e-05	165	148	6	dc570154baed59ed109e5369589448e075ba66a9
ToppCell	356C-Myeloid-Dendritic-cDC1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	TCEA3 DYSF CD38 LRP6 C10orf105 ASB2	1.97e-05	166	148	6	971ee6602a1e751f453f9d823295e63dadce62bf
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCEA3 CLDN22 NT5DC2 ELAPOR1 ASB2 MUC5AC	2.18e-05	169	148	6	db73dae011ff3749b3706e50ab46d03b775dd6bb
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCEA3 CLDN22 NT5DC2 ELAPOR1 ASB2 MUC5AC	2.18e-05	169	148	6	97b7047b87ce0052d8580565c9b44fd2aa6f0d5c
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCEA3 CLDN22 NT5DC2 ELAPOR1 ASB2 MUC5AC	2.18e-05	169	148	6	1a684471dbda42e1470e5a889648666e14f25982
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	TCEA3 LMO3 PTCHD1 ZNF608 ELAPOR1 C10orf105	2.25e-05	170	148	6	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 ADAMTS3 LMO3 PRAG1 ITPKA SV2B	2.74e-05	176	148	6	07abf29d681abdd6c7cc87f9eaf9377e92ce212c
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 ADAMTS3 LMO3 PRAG1 ITPKA SV2B	2.74e-05	176	148	6	c7be4eaa5eb76ad9389fb9d15ad0934e88d267d1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GRIN2A ADAMTSL3 PXK PPP3CA ADAMTS18 FBN3	2.74e-05	176	148	6	6c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 ADAMTS3 LMO3 PRAG1 ITPKA SV2B	2.83e-05	177	148	6	8b003ed7887479c3a010ef37dd981b748256bda7
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OCRL GFRA3 PTCHD1 SV2B ELAPOR1 ADAMTS18	2.83e-05	177	148	6	1dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CLDN22 FBN1 LMX1B ELAPOR1 ASB2 MUC5AC	2.83e-05	177	148	6	709235694cc711b9b79690e23c94577b2ae06811
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OCRL GFRA3 PTCHD1 SV2B ELAPOR1 ADAMTS18	2.83e-05	177	148	6	426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CLDN22 FBN1 LMX1B ELAPOR1 ASB2 MUC5AC	2.83e-05	177	148	6	7f9c2a45a994b32f15e5693f7cb873716a4eb568
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRIN2A ADAMTSL3 PXK PPP3CA ADAMTS18 FBN3	2.92e-05	178	148	6	51d2188406f04329311b2efd1108fc36617a860e
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 ADAMTS3 LMO3 PRAG1 ITPKA SV2B	2.92e-05	178	148	6	5d6297f34e104bacefb25c4e2338b50fe13dd19a
ToppCell	control-Lymphoid-NKT-proliferating\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KIF4A FABP5 FBN1 SHCBP1 ANO7 KHK	3.11e-05	180	148	6	535535a67b3f3320bad2f98b1bc98a7b0ee77840
ToppCell	Control-Myeloid-DC1\|Control / Condition, Lineage and Cell class	PRR22 FSIP2 ZNF608 CD38 C10orf105 ASB2	3.20e-05	181	148	6	5a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS3 LMO3 ADAMTSL3 ZNF608 SHCBP1 SSH2	3.62e-05	185	148	6	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCEA3 CLDN22 LMX1B NT5DC2 ELAPOR1 MUC5AC	3.62e-05	185	148	6	5dee5645240637e135677732a35fd416b37367d4
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABCA3 SORBS2 LMO3 LDLR ZNF608 LRP6	4.32e-05	191	148	6	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	Control-Control-Myeloid-Neutrophil\|Control / Disease, condition lineage and cell class	ST20 ARHGAP26 NUTM2A NCOA4 DYSF ELAPOR1	5.58e-05	200	148	6	95c41f147a1594d49e73cb56d86d301c3115ce20
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-7\|TCGA-Stomach / Sample_Type by Project: Shred V9	AKAP6 SORBS2 NEXMIF PTCHD1 PLXNA4	6.63e-05	127	148	5	5e4d110cc6e68cd8fc7a4771a65e6f8cd83e7721
Disease	Sotos syndrome 1 (implicated_via_orthology)	NSD1 NSD3	6.97e-05	3	143	2	DOID:0112103 (implicated_via_orthology)
Disease	connective tissue disease (implicated_via_orthology)	FBN1 FBN3	6.97e-05	3	143	2	DOID:65 (implicated_via_orthology)
Disease	Diffuse Large B-Cell Lymphoma	SEC31A MALT1 KMT2D NOTCH2	1.49e-04	55	143	4	C0079744
Disease	Endometrial Stromal Sarcoma	NUTM2A NUTM2B	2.31e-04	5	143	2	C0206630
Disease	3-methyl-2-oxovalerate measurement	SORBS2 ASTN2	2.31e-04	5	143	2	EFO_0021021
Disease	Autistic Disorder	NSD1 TSC2 GRIN2A PTCHD1 ASMT PLA2G4A ASTN2	2.94e-04	261	143	7	C0004352
Disease	smoking behavior, BMI-adjusted waist circumference	ADAMTS3 PEPD NSD1 ADAMTSL3 NT5DC2	3.28e-04	122	143	5	EFO_0004318, EFO_0007789
Disease	vital capacity	ADAMTS3 ARHGAP26 WDR70 WDR27 GRIN2A ODAD2 RREB1 ADAMTSL3 ZZEF1 LMX1B ADAMTS18 LRP6 ASTN2 H1-10-AS1 FBN3 OTOG	3.38e-04	1236	143	16	EFO_0004312
Disease	Clear cell sarcoma of kidney	NUTM2E NUTM2B	3.45e-04	6	143	2	C0334488
Disease	renal cell carcinoma (implicated_via_orthology)	TSC2 FLCN	3.45e-04	6	143	2	DOID:4450 (implicated_via_orthology)
Disease	sudden cardiac arrest	LAMA1 GRIN2A CHRNB4 UPP2	7.22e-04	83	143	4	EFO_0004278
Disease	Cataract microcornea syndrome	ABCA3 CRYAA	8.21e-04	9	143	2	C1861829
Disease	autism spectrum disorder (implicated_via_orthology)	ABCA3 VRK3 NEXMIF TSC2 CHD6	8.91e-04	152	143	5	DOID:0060041 (implicated_via_orthology)
Disease	sexual dimorphism measurement	ADAMTS3 ARHGAP26 WDR70 NSD1 TSC2 RHOT2 GRIN2A DYSF ADAMTSL3 ZZEF1 LDLR FBN1 ZNF608 LINC00471	9.96e-04	1106	143	14	EFO_0021796
Disease	age-related hearing impairment	ZNF185 ADGRB2 NSD1 ADAMTSL3 SV2B PLXNA4 C10orf105	1.06e-03	324	143	7	EFO_0005782
Disease	cortical thickness	AKAP6 ADAMTS3 LAMA1 ARHGAP35 RREB1 DYSF ADAMTSL3 PXK FBN1 NT5DC2 CBY2 ADAMTS18 ASTN2 SSH2	1.06e-03	1113	143	14	EFO_0004840
Disease	body surface area	ADAMTS3 ARHGAP26 NSD1 RREB1 ADAMTSL3 GFRA3 FBN1 ZNF608 LMO1 ASTN2	1.20e-03	643	143	10	EFO_0022196
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	ADAMTS3 LDLR	2.04e-03	14	143	2	EFO_0004611, EFO_0008589
Disease	DiGeorge Syndrome	DGCR2 RREB1	2.68e-03	16	143	2	C0012236
Disease	CONOTRUNCAL ANOMALY FACE SYNDROME	DGCR2 RREB1	2.68e-03	16	143	2	C0795907
Disease	migraine without aura, susceptibility to, 4	STXBP2 ASTN2	2.68e-03	16	143	2	MONDO_0011847
Disease	Shprintzen syndrome	DGCR2 RREB1	2.68e-03	16	143	2	C0220704
Disease	Lipidemias	LDLR LMX1B	3.02e-03	17	143	2	C1706412
Disease	Hyperlipidemia	LDLR LMX1B	3.02e-03	17	143	2	C0020473
Disease	BMI-adjusted waist circumference, physical activity measurement	ADAMTS3 PEPD NSD1 ADAMTSL3	3.07e-03	123	143	4	EFO_0007789, EFO_0008002
Disease	syndrome (implicated_via_orthology)	NSD1 NSD3	3.39e-03	18	143	2	DOID:225 (implicated_via_orthology)
Disease	level of Sphingomyelin (d34:1) in blood serum	ADAMTS3 LDLR	3.39e-03	18	143	2	OBA_2045175
Disease	Osteoarthritis of hip	LMX1B ASTN2	4.18e-03	20	143	2	C0029410
Disease	cortisol measurement	LDLR MKNK1	4.18e-03	20	143	2	EFO_0005843
Disease	anorexia nervosa	AKAP6 NCKIPSD PPP3CA	4.81e-03	70	143	3	MONDO_0005351

Protein segments in the cluster

Peptide	Gene	Start	Entry
LPSDCGEKMTLCISV	CHRNB4	256	P30926
CEGPELQTKLCSMAA	ADGRB2	401	O60241
TDLCFSPDGKMLISA	APAF1	1181	O14727
MDCSCVSDLLFAPPA	ERFL	1	A0A1W2PQ73
CCVPEKMSSLSILFF	BMP3	436	P12645
GMQCKDFDSFLALPA	CLDN24	61	A6NM45
MGKCPTREDQCSELF	ADAM7	501	Q9H2U9
LLKFLMDLGCDGEPC	ASB2	491	Q96Q27
PCTKCTRDMATFLAE	APOBEC3G	96	Q9HC16
MPDSAAALLGTCCKL	GSDME	396	O60443
TGERPFMCETCGKSF	GZF1	486	Q9H116
ASCCVMPPDLTAFAK	GCLM	191	P48507
MAKGELQCCGSSLFL	ABCA3	736	Q99758
CCLKLAFLDPISGKM	BRWD3	1001	Q6RI45
ECMSLYPGCKITVFD	ASMT	196	P46597
SFRCECPEGLMLDAS	FBN3	891	Q75N90
STDLLMKCSLNPGCD	PIK3AP1	426	Q6ZUJ8
DKESFCRGFPMSGCE	LINC00471	76	Q8N535
DGKSCLMLSDVCEGP	ASTN2	746	O75129
MECALLLACAFPAAG	ADAMTS18	1	Q8TE60
MANCEFSPVSGDKPC	CD38	1	P28907
ICGKEAASFCEMCPS	NSD1	2166	Q96L73
EACMAGCDKAFTPFS	PEPD	476	P12955
FSSAKGCLLMPSSED	LTN1	831	O94822
GNCAACSKLIPAFEM	LMO1	86	P25800
MLPCDEAGCLLFSQA	CAPN15	601	O75808
TQELCGSKDSFEMCP	ANO7	381	Q6IWH7
GSKDSFEMCPLCLDC	ANO7	386	Q6IWH7
RVASFSCMCPEGKAG	NOTCH2	356	Q04721
LCLPGFTGDKCQTDM	NOTCH2	936	Q04721
PKKSDMCEGCRSLAA	FLCN	76	Q8NFG4
AAALRSCPMCQKEFA	FAAP20	141	Q6NZ36
LPESMCLKFDCGVQI	MALT1	586	Q9UDY8
KDCDLPAADSCAIME	ELAPOR1	951	Q6UXG2
DCLMKTTCGTPEYIA	PSKH1	251	P11801
CGVDMDTSFASCGLK	FSIP2	1496	Q5CZC0
MDCPCDLADGLKVVL	RCE1	136	Q9Y256
AMRESCGLCLKADPD	PLXNA4	806	Q9HCM2
DLCLSCVTVPKMLGD	OR4Q3	71	Q8NH05
FCDVPAVMALSCSDK	OR5B2	176	Q96R09
LPCFEASDCKESSPM	NANOG	11	Q9H9S0
ENGLMCPACTASFRD	PINLYP	121	A6NC86
GCATESMCFTKPGAE	PINLYP	171	A6NC86
PCTSLKSEDATFMCD	NFX1	671	Q12986
NCAACSKLIPAFEMV	LMO3	76	Q8TAP4
RCACPIGFELISDMK	LRP6	611	O75581
SSDCCMALLQDIFGP	GBP2	401	P32456
AGCMKTCPLIDLEVD	GGA2	341	Q9UJY4
LAMPKAALLNDCVCD	GAS1	211	P54826
DSLVSMKCSLFRFCP	LRGUK	736	Q96M69
KACPPLSCSLDEARM	MUC5AC	5496	P98088
GAMAKPDCIITCDGK	FABP5	36	Q01469
KKLMPCASCTAAEPD	H1-10-AS1	46	Q4G0G2
LLDGFDGPCVLDCKM	ITPKA	251	P23677
VCSDMKRDTLFGPCG	MIB1	821	Q86YT6
HFFCDAPPLVKMSCT	OR9G4	191	Q8NGQ1
GLPAVCDLFACMQLK	NCOA4	586	Q13772
MSPLECSECFGDQLL	CBY2	1	Q8NA61
GMQCKDFDSFLALPA	CLDN22	61	Q8N7P3
SSSEGFICPQCMKSL	EEA1	36	Q15075
FICPQCMKSLGSADE	EEA1	41	Q15075
FCPEADSKTMLQCLK	GLG1	891	Q92896
NDEPCLGDKSIFCQM	ADAMTS3	1016	O15072
PTCEVKSCDDFMGQL	CR1	351	P17927
PTCEVKSCDDFMGQL	CR1	801	P17927
KPDSDLCLKFAMLCT	GFRA3	156	O60609
LMSISKEGELCCSEA	CHD6	1781	Q8TD26
SCTCFAPLPAGADMD	DBNDD2	86	Q9BQY9
GSFKCQCPSGMTLDA	FBN1	931	P35555
CDMGFVPSADGKACE	FBN1	1431	P35555
SLMCLAKCLESEKDG	CEP89	621	Q96ST8
KCSDEGLTALSMCFL	ANKMY1	321	Q9P2S6
ECCKFMCLDPDGNSL	DGCR2	326	P98153
PKEISEGCQMCLSFV	KIF4A	21	O95239
PKEISEGCQMCLSFV	KIF4B	21	Q2VIQ3
SCTVLSLLGAPCAFM	KHK	46	P50053
KFFPNCGDSTLAMCG	DCAF8L1	246	A6NGE4
CSLSADGMLTFCGPK	CRYAA	131	P02489
CTLEPVFGKMFELTC	DYSF	1621	O75923
DACMDAFDCLPLAAL	PPP3CA	176	Q08209
EAKCACTDSMGVPRA	OTOG	2431	Q6ZRI0
FFCDTSPILALSCMD	OR8H1	176	Q8NGG4
CPDLRFSMALCDQEK	PLA2G4A	141	P47712
ALADGLCSMKLSPPC	MKNK1	426	Q9BUB5
FCDLGPLMKVSCSDA	OR1P1	191	Q8NH06
MEVKGPSGRSFCCES	NUTM2A	1	Q8IVF1
MEVKGPSGRSFCCES	NUTM2B	1	A6NNL0
MEVKGPSGRSFCCES	NUTM2E	1	B1AL46
ALCMEKSLGPNSCSA	HPX	406	P02790
FAEGSCPANDMVLCL	SZT2	1021	Q5T011
ESTVFAAMCGLCGLK	UPP2	256	O95045
SRSGSCPCLMAKADP	SSPOP	4331	A2VEC9
FALPSAEKDMCLSSS	SV2B	131	Q7L1I2
CDVACLMFDGSDPKS	RHOT2	486	Q8IXI1
DNCAPMLSTFVLGKD	PTCHD1	766	Q96NR3
DLLADFDSPCVMDCK	ITPKB	731	P27987
CLGCFMESKDAVDPE	NEXMIF	146	Q5QGS0
EFCTVCFSPFKLLGM	PRDM15	246	P57071
ALCPCIKNAKDAGEM	ODAD2	861	Q5T2S8
STNATCGEKGPEMFC	LAMA1	36	P25391
KSCLTFTDDGCGMTP	MORC4	81	Q8TE76
MGLPALEFSDCCLDS	ARHGAP26	1	Q9UNA1
KCFLTAMRESGAHCP	RNF138	41	Q8WVD3
DGENGFKFSPVCCDM	TENM1	156	Q9UKZ4
FKFSPVCCDMEAQAG	TENM1	161	Q9UKZ4
SCKELSRMGPCSFAE	NLRP7	211	Q8WX94
MCICADFEKVFSIGP	DARS1	256	P14868
CATGKMELCARTDPS	SHCBP1	591	Q8NEM2
ERILDMCCAPGGKTS	NOP2	386	P46087
MCLMCGDPFSADDIL	ARHGAP35	786	Q9NRY4
LPSCFGTSLEALCRM	OCRL	676	Q01968
GSLLCEEDSKESCPM	SORBS2	406	O94875
LKCFGAMCSLDAAII	NCKIPSD	461	Q9NZQ3
LMAAAALSKGCASCI	SLC25A33	236	Q9BSK2
DDAPSMAGKSAGCCL	AKAP6	2006	Q13023
AAARCFLMACEKPGK	COA7	91	Q96BR5
TCLLFMTLCKPAALD	C10orf105	51	Q8TEF2
ASGCPLFCPVSKMEA	TRAF2	466	Q12933
LEDAMKLFDCLPGAS	PRR22	286	Q8IZ63
ADRPFVCEMCTKGFT	ZBTB14	301	O43829
GKPSELCQSFECMVG	ZNF440	521	Q8IYI8
PLMLDLAPFCSATCK	USP45	706	Q70EL2
LAKDSGMCNPEGCLT	SSH2	816	Q76I76
FVCDTCDKAFPMLCS	RREB1	316	Q92766
TGKICEMLFCPEAIL	ST20	36	Q9HBF5
DLKDPCKLDMNFGSC	SPINT4	36	Q6UDR6
MTDCCFSPDDKLIVT	WDR70	426	Q9NW82
SPLFGLDCEMCLTSK	REXO5	226	Q96IC2
VASMKAVPAASCLGD	STYXL2	751	Q5VZP5
LSSCCKMSDILAEGI	STXBP2	41	Q15833
LESTLSCEACKNGMP	PXK	371	Q7Z7A4
ASSMCLLAPCYLTGD	TCEA3	171	O75764
MISFCPDCGKSIQAA	VRK3	1	Q8IV63
DQLCTGCMKTPFLGD	NT5DC2	501	Q9H857
CLNPESLKMSACSDF	PRAG1	6	Q86YV5
GLASLPDSKFICMEC	NSD3	731	Q9BZ95
ECMECGKALGFSRSL	ZNF124	151	Q15973
ADSETDAIICPMCKA	nan	101	Q8NA96
LLHSGEMPFSCECGK	ZNF786	641	Q8N393
MCPVEGCGKSFTRAE	ZXDA	481	P98168
MESCAFKAALACVGG	TIMM22	66	Q9Y584
CSAADGSLAAEMPKL	ZNF608	686	Q9ULD9
SDMDLCKTCFLGGVK	ZZEF1	1801	O43149
CCRLVEMDSKSGPGL	TTC37	261	Q6PGP7
PFKCMECEKAFSCSS	ZNF23	531	P17027
ECKACGMAFSSGSAL	ZNF345	231	Q14585
LACSMQDCAFPLDGT	WDR27	36	A2RRH5
FELDLSDPSLDMKSC	SEC31A	46	O94979
GLCMIFVADCLCPSK	TMX1	196	Q9H3N1
FKCGICSKPMGDLLD	ZNF185	656	O15231
DQLCSALCSMLSGPK	TSC2	731	P49815
SLAPMDSLKAECRYC	ZBED4	466	O75132
CSMDPCPSSDGFKEI	ADAMTSL3	396	P82987
KPGNDSKMLVCETCD	KMT2D	281	O14686
SPKFTCACPDGMLLA	LDLR	691	P01130
FAAKCSGCMEKIAPT	LMX1B	111	O60663
GHFTMRSPFKCDACL	GRIN2A	1226	Q12879