Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	postsynapse organization	MAGI2 ABL2 PTPRD PRICKLE1 ABI2 PTPRS ROR2 CAPRIN2 GDNF	4.22e-06	313	82	9	GO:0099173
GeneOntologyBiologicalProcess	cell junction organization	CACNA1A MAGI2 ABL2 PTPRD PRICKLE1 ABI2 PTPRS ROR2 CGN CAPRIN2 TJP2 FLCN TNS1 GDNF	2.74e-05	974	82	14	GO:0034330
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	CACNA1A NTN4 ABL2 PTPRD PRICKLE1 ABI2 PTPRS CAPRIN2 PCDHAC2 RET GDNF WDR47	3.82e-05	748	82	12	GO:0048667
GeneOntologyBiologicalProcess	neuron projection development	CACNA1A MAGI2 NTN4 ARID1B ABL2 PTPRD PRICKLE1 ABI2 PTPRS ROR2 CAPRIN2 HLA-E PCDHAC2 RET GDNF WDR47	3.93e-05	1285	82	16	GO:0031175
GeneOntologyBiologicalProcess	embryonic epithelial tube formation	STK3 ABL2 PRICKLE1 RET STIL GDNF	4.12e-05	159	82	6	GO:0001838
GeneOntologyBiologicalProcess	dendrite development	CACNA1A ARID1B ABL2 PTPRD PRICKLE1 ABI2 PTPRS CAPRIN2	5.59e-05	335	82	8	GO:0016358
GeneOntologyBiologicalProcess	epithelial tube formation	STK3 ABL2 PRICKLE1 RET STIL GDNF	6.60e-05	173	82	6	GO:0072175
GeneOntologyBiologicalProcess	Wnt signaling pathway, planar cell polarity pathway	MAGI2 ABL2 PRICKLE1 ROR2	6.78e-05	55	82	4	GO:0060071
GeneOntologyBiologicalProcess	neuron projection morphogenesis	CACNA1A NTN4 ABL2 PTPRD PRICKLE1 ABI2 PTPRS CAPRIN2 PCDHAC2 RET GDNF WDR47	7.48e-05	802	82	12	GO:0048812
GeneOntologyBiologicalProcess	regulation of postsynaptic density assembly	PTPRD PRICKLE1 PTPRS	7.65e-05	21	82	3	GO:0099151
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	CACNA1A NTN4 ABL2 PTPRD PRICKLE1 ABI2 PTPRS CAPRIN2 PCDHAC2 RET GDNF WDR47	9.12e-05	819	82	12	GO:0120039
GeneOntologyBiologicalProcess	regulation of postsynapse organization	PTPRD PRICKLE1 ABI2 PTPRS ROR2 CAPRIN2	9.55e-05	185	82	6	GO:0099175
GeneOntologyBiologicalProcess	cell projection morphogenesis	CACNA1A NTN4 ABL2 PTPRD PRICKLE1 ABI2 PTPRS CAPRIN2 PCDHAC2 RET GDNF WDR47	9.89e-05	826	82	12	GO:0048858
GeneOntologyBiologicalProcess	tube formation	STK3 ABL2 PRICKLE1 RET STIL GDNF	1.01e-04	187	82	6	GO:0035148
GeneOntologyBiologicalProcess	morphogenesis of embryonic epithelium	STK3 ABL2 PRICKLE1 RET STIL GDNF	1.11e-04	190	82	6	GO:0016331
GeneOntologyBiologicalProcess	regulation of postsynaptic specialization assembly	PTPRD PRICKLE1 PTPRS	1.47e-04	26	82	3	GO:0099150
GeneOntologyBiologicalProcess	regulation of excitatory synapse assembly	PTPRD PRICKLE1 PTPRS	1.47e-04	26	82	3	GO:1904889
GeneOntologyBiologicalProcess	regulation of neuron projection development	CACNA1A MAGI2 ABL2 PTPRD ABI2 PTPRS ROR2 CAPRIN2 HLA-E RET	1.54e-04	612	82	10	GO:0010975
GeneOntologyBiologicalProcess	regulation of postsynaptic density organization	PTPRD PRICKLE1 PTPRS	1.65e-04	27	82	3	GO:1905874
GeneOntologyBiologicalProcess	neuron development	CACNA1A MAGI2 NTN4 ARID1B ABL2 PTPRD PRICKLE1 ABI2 PTPRS ROR2 CAPRIN2 HLA-E PCDHAC2 RET GDNF WDR47	1.81e-04	1463	82	16	GO:0048666
GeneOntologyBiologicalProcess	epithelium development	STK3 ENAM MAGI2 NTN4 ABL2 PRICKLE1 ABI2 PTPRS ROR2 CGN TJP2 RET STIL GDNF AXIN2 CEP63	1.89e-04	1469	82	16	GO:0060429
GeneOntologyBiologicalProcess	cell morphogenesis	ENAM CACNA1A NTN4 ABL2 PTPRD PRICKLE1 ABI2 PTPRS CGN CAPRIN2 PCDHAC2 RET GDNF WDR47	2.39e-04	1194	82	14	GO:0000902
GeneOntologyBiologicalProcess	dendritic spine development	ARID1B PTPRD ABI2 PTPRS CAPRIN2	2.49e-04	141	82	5	GO:0060996
GeneOntologyBiologicalProcess	non-canonical Wnt signaling pathway	MAGI2 ABL2 PRICKLE1 ROR2	2.52e-04	77	82	4	GO:0035567
GeneOntologyBiologicalProcess	postsynaptic density assembly	PTPRD PRICKLE1 PTPRS	3.32e-04	34	82	3	GO:0097107
GeneOntologyBiologicalProcess	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	DET1 PRICKLE1 RNF180 AXIN2	3.68e-04	85	82	4	GO:0032436
GeneOntologyBiologicalProcess	synapse organization	CACNA1A MAGI2 ABL2 PTPRD PRICKLE1 ABI2 PTPRS ROR2 CAPRIN2 GDNF	3.79e-04	685	82	10	GO:0050808
GeneOntologyBiologicalProcess	cell junction assembly	CACNA1A MAGI2 PTPRD PRICKLE1 ABI2 PTPRS CGN FLCN TNS1	4.25e-04	569	82	9	GO:0034329
GeneOntologyBiologicalProcess	protein localization to centrosome	STK3 STIL CEP63	4.62e-04	38	82	3	GO:0071539
GeneOntologyBiologicalProcess	multicellular organism growth	KMT2C ABL2 PRICKLE1 HLA-E COX10 STIL	4.74e-04	249	82	6	GO:0035264
GeneOntologyBiologicalProcess	positive regulation of neuron projection development	MAGI2 ABL2 PTPRD ROR2 CAPRIN2 RET	4.74e-04	249	82	6	GO:0010976
GeneOntologyBiologicalProcess	protein localization to microtubule organizing center	STK3 STIL CEP63	4.99e-04	39	82	3	GO:1905508
GeneOntologyBiologicalProcess	postsynapse assembly	MAGI2 PTPRD PRICKLE1 PTPRS	5.18e-04	93	82	4	GO:0099068
GeneOntologyBiologicalProcess	synaptic membrane adhesion	MAGI2 PTPRD PTPRS	6.22e-04	42	82	3	GO:0099560
GeneOntologyBiologicalProcess	postsynaptic specialization assembly	PTPRD PRICKLE1 PTPRS	7.13e-04	44	82	3	GO:0098698
GeneOntologyCellularComponent	bicellular tight junction	MAGI1 MAGI2 CGN TJP2 NHS	1.57e-04	131	81	5	GO:0005923
GeneOntologyCellularComponent	centrosome	STK3 MAGI2 CAPRIN2 MAMLD1 FLCN STIL FIGN CDC25B CEP57 AXIN2 CEP63	1.82e-04	770	81	11	GO:0005813
GeneOntologyCellularComponent	tight junction	MAGI1 MAGI2 CGN TJP2 NHS	2.07e-04	139	81	5	GO:0070160
GeneOntologyCellularComponent	apical junction complex	MAGI1 MAGI2 CGN TJP2 NHS	3.73e-04	158	81	5	GO:0043296
GeneOntologyCellularComponent	microtubule organizing center	STK3 MAGI2 CAPRIN2 MAMLD1 FLCN STIL FIGN CDC25B CEP57 AXIN2 CEP63	8.11e-04	919	81	11	GO:0005815
HumanPheno	Intestinal polyposis	FLCN RET CEP57 GDNF AXIN2	3.02e-05	62	31	5	HP:0200008
HumanPheno	Intestinal polyp	FLCN RET CEP57 GDNF AXIN2	4.41e-05	67	31	5	HP:0005266
Domain	GUANYLATE_KINASE_2	MAGI1 MAGI2 TJP2	1.31e-04	23	81	3	PS50052
Domain	GUANYLATE_KINASE_1	MAGI1 MAGI2 TJP2	1.31e-04	23	81	3	PS00856
Domain	Guanylate_kin	MAGI1 MAGI2 TJP2	1.90e-04	26	81	3	PF00625
Domain	GK/Ca_channel_bsu	MAGI1 MAGI2 TJP2	1.90e-04	26	81	3	IPR008145
Domain	Guanylate_kin-like_dom	MAGI1 MAGI2 TJP2	1.90e-04	26	81	3	IPR008144
Domain	GuKc	MAGI1 MAGI2 TJP2	1.90e-04	26	81	3	SM00072
Domain	SH3	DOCK4 ABL2 EFS ABI2 TJP2 NCF4	3.52e-04	216	81	6	SM00326
Domain	SH3	DOCK4 ABL2 EFS ABI2 TJP2 NCF4	3.52e-04	216	81	6	PS50002
Domain	SH3_domain	DOCK4 ABL2 EFS ABI2 TJP2 NCF4	3.88e-04	220	81	6	IPR001452
Domain	Guanylate_kinase_CS	MAGI1 MAGI2	2.14e-03	16	81	2	IPR020590
Domain	PTPc_motif	PTPRD PTPRS TNS1	2.14e-03	59	81	3	SM00404
Domain	Tyr_Pase_cat	PTPRD PTPRS TNS1	2.14e-03	59	81	3	IPR003595
Domain	PDZ	MAGI1 MAGI2 TJP2 APBA3	3.30e-03	141	81	4	PF00595
Domain	P-loop_NTPase	MAGI1 MAGI2 DDX46 SAMD9 TJP2 PFKFB2 CDC6 FIGN RAB5B MYO5C	3.58e-03	848	81	10	IPR027417
Domain	PDZ	MAGI1 MAGI2 TJP2 APBA3	3.93e-03	148	81	4	SM00228
Domain	-	MAGI1 MAGI2 TJP2 APBA3	4.12e-03	150	81	4	2.30.42.10
Domain	PDZ	MAGI1 MAGI2 TJP2 APBA3	4.22e-03	151	81	4	PS50106
Domain	PDZ	MAGI1 MAGI2 TJP2 APBA3	4.32e-03	152	81	4	IPR001478
Domain	SH3_1	ABL2 EFS ABI2 NCF4	5.64e-03	164	81	4	PF00018
Domain	TyrKc	ABL2 ROR2 RET	6.62e-03	88	81	3	SM00219
Domain	Tyr_kinase_cat_dom	ABL2 ROR2 RET	6.62e-03	88	81	3	IPR020635
Domain	EGF_LAM_2	NTN4 ATRNL1	7.47e-03	30	81	2	PS50027
Domain	EGF_LAM_1	NTN4 ATRNL1	7.47e-03	30	81	2	PS01248
Domain	-	PTPRD PTPRS TNS1	7.48e-03	92	81	3	3.90.190.10
Domain	PROTEIN_KINASE_TYR	ABL2 ROR2 RET	8.65e-03	97	81	3	PS00109
Domain	Tyr_kinase_AS	ABL2 ROR2 RET	8.65e-03	97	81	3	IPR008266
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	STK3 DOCK4 MAGI1 ABL2 FAM171A2 SYNJ1 ELMO2 ROR2 CGN TJP2 NHS PFKFB2 STIL CDC25B RNF180 TAB3	1.58e-10	861	82	16	36931259
Pubmed	Specification of neural circuit architecture shaped by context-dependent patterned LAR-RPTP microexons.	PTPRD PTPRS SST	2.51e-07	6	82	3	38388459
Pubmed	Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases.	PTPRD PTPRS RET	2.51e-07	6	82	3	19273906
Pubmed	Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.	STK3 MAGI1 ELMO2 FLCN CDC25B AXIN2	6.15e-07	128	82	6	25332235
Pubmed	Lgr4-deficient mice showed premature differentiation of ureteric bud with reduced expression of Wnt effector Lef1 and Gata3.	RET GDNF AXIN2	1.05e-06	9	82	3	21523854
Pubmed	Non-canonical Wnt5a/Ror2 signaling regulates kidney morphogenesis by controlling intermediate mesoderm extension.	ROR2 RET GDNF	1.50e-06	10	82	3	25082826
Pubmed	Lrp4 regulates initiation of ureteric budding and is crucial for kidney formation--a mouse model for Cenani-Lenz syndrome.	RET GDNF AXIN2	2.06e-06	11	82	3	20454682
Pubmed	Role of Wnt5a-Ror2 signaling in morphogenesis of the metanephric mesenchyme during ureteric budding.	ROR2 RET GDNF	2.74e-06	12	82	3	24891614
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DOCK4 ABL2 SYNJ1 ABI2 ELMO2 CGN ZNF507 TJP2 PATL1 STIL TAB3	5.20e-06	853	82	11	28718761
Pubmed	Functional RET G691S polymorphism in cutaneous malignant melanoma.	RET GDNF	5.49e-06	2	82	2	19561646
Pubmed	RET and GDNF mutations are rare in fetuses with renal agenesis or other severe kidney development defects.	RET GDNF	5.49e-06	2	82	2	21490379
Pubmed	Expression Analysis of GDNF/RET Signaling Pathway in Human AD-MSCs Grown in HEK 293 Conditioned Medium (HEK293-CM).	RET GDNF	5.49e-06	2	82	2	32803668
Pubmed	GDNF-independent ureteric budding: role of PI3K-independent activation of AKT and FOSB/JUN/AP-1 signaling.	RET GDNF	5.49e-06	2	82	2	24143282
Pubmed	Acute stress disrupts intestinal homeostasis via GDNF-RET.	RET GDNF	5.49e-06	2	82	2	32808420
Pubmed	Vitamin D regulation of GDNF/Ret signaling in dopaminergic neurons.	RET GDNF	5.49e-06	2	82	2	29018141
Pubmed	Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse model.	RET GDNF	5.49e-06	2	82	2	27607574
Pubmed	The in vivo response of stem and other undifferentiated spermatogonia to the reversible inhibition of glial cell line-derived neurotrophic factor signaling in the adult.	RET GDNF	5.49e-06	2	82	2	22232066
Pubmed	c-RET molecule in malignant melanoma from oncogenic RET-carrying transgenic mice and human cell lines.	RET GDNF	5.49e-06	2	82	2	20422010
Pubmed	The relationship between overexpression of glial cell-derived neurotrophic factor and its RET receptor with progression and prognosis of human pancreatic cancer.	RET GDNF	5.49e-06	2	82	2	18652760
Pubmed	Co-expression of activin receptor-interacting protein 1 and 2 in mouse nerve cells.	MAGI1 MAGI2	5.49e-06	2	82	2	23523645
Pubmed	Protein kinase A regulates GDNF/RET-dependent but not GDNF/Ret-independent ureteric bud outgrowth from the Wolffian duct.	RET GDNF	5.49e-06	2	82	2	20816800
Pubmed	High expression of the RET receptor tyrosine kinase and its ligand GDNF identifies a high-risk subset of estrogen receptor positive breast cancer.	RET GDNF	5.49e-06	2	82	2	37061618
Pubmed	RET recognition of GDNF-GFRα1 ligand by a composite binding site promotes membrane-proximal self-association.	RET GDNF	5.49e-06	2	82	2	25242331
Pubmed	Modulation of the tyrosine kinase receptor Ret/glial cell-derived neurotrophic factor (GDNF) signaling: a new player in reproduction induced anterior pituitary plasticity?	RET GDNF	5.49e-06	2	82	2	21239429
Pubmed	The adhesion GPCR GPR116/ADGRF5 has a dual function in pancreatic islets regulating somatostatin release and islet development.	ADGRF5 SST	5.49e-06	2	82	2	38228886
Pubmed	Bimodal regulation of axonal transport by the GDNF-RET signalling axis in healthy and diseased motor neurons.	RET GDNF	5.49e-06	2	82	2	35798698
Pubmed	GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors.	RET GDNF	5.49e-06	2	82	2	23650283
Pubmed	MAGI1 copy number variation in bipolar affective disorder and schizophrenia.	MAGI1 MAGI2	5.49e-06	2	82	2	22381734
Pubmed	High glucose promotes cell proliferation and enhances GDNF and RET expression in pancreatic cancer cells.	RET GDNF	5.49e-06	2	82	2	20960036
Pubmed	Gdnf haploinsufficiency causes Hirschsprung-like intestinal obstruction and early-onset lethality in mice.	RET GDNF	5.49e-06	2	82	2	11774071
Pubmed	The second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigma.	PTPRD PTPRS	5.49e-06	2	82	2	9566880
Pubmed	RET-mediated glial cell line-derived neurotrophic factor signaling inhibits mouse prostate development.	RET GDNF	5.49e-06	2	82	2	28506996
Pubmed	Responses to glial cell line-derived neurotrophic factor change in mice as spermatogonial stem cells form progenitor spermatogonia which replicate and give rise to more differentiated progeny.	RET GDNF	5.49e-06	2	82	2	25165119
Pubmed	GDNF restores human blood-nerve barrier function via RET tyrosine kinase-mediated cytoskeletal reorganization.	RET GDNF	5.49e-06	2	82	2	22326552
Pubmed	Mutations of the RET-GDNF signaling pathway in Ondine's curse.	RET GDNF	5.49e-06	2	82	2	9497256
Pubmed	Hirschsprung associated GDNF mutations do not prevent RET activation.	RET GDNF	5.49e-06	2	82	2	11973622
Pubmed	Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state.	RET GDNF AXIN2	6.92e-06	16	82	3	18177851
Pubmed	Constitutive metanephric mesenchyme-specific expression of interferon-gamma causes renal dysplasia by regulating Sall1 expression.	RET GDNF AXIN2	8.39e-06	17	82	3	29771971
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	KMT2C NOL4L ARID1B SYNJ1 PPRC1 ATRNL1 ZNF507 TJP2 SERINC3 PATL1 TNS1 CEP63	8.80e-06	1084	82	12	11544199
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1A MAGI1 MAGI2 PTPRD FAM171A2 SYNJ1 ABI2 PTPRS DDN TNS1 WDR47	1.62e-05	963	82	11	28671696
Pubmed	Achalasia: will genetic studies provide insights?	RET GDNF	1.64e-05	3	82	2	20700745
Pubmed	Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system progenitor cells during mammalian embryogenesis.	RET GDNF	1.64e-05	3	82	2	12399307
Pubmed	Endoneurial macrophages induce perineural invasion of pancreatic cancer cells by secretion of GDNF and activation of RET tyrosine kinase receptor.	RET GDNF	1.64e-05	3	82	2	22971345
Pubmed	GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF.	RET GDNF	1.64e-05	3	82	2	8674117
Pubmed	Glial-derived neurotropic factor and RET gene expression in normal human anterior pituitary cell types and in pituitary tumors.	RET GDNF	1.64e-05	3	82	2	11932334
Pubmed	LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.	PTPRD PTPRS	1.64e-05	3	82	2	31985401
Pubmed	Expression patterns of the glial cell line-derived neurotrophic factor, neurturin, their cognate receptors GFRalpha-1, GFRalpha-2, and a common signal transduction element c-Ret in the human skin hair follicles.	RET GDNF	1.64e-05	3	82	2	18222320
Pubmed	CaV 2.1 ablation in cortical interneurons selectively impairs fast-spiking basket cells and causes generalized seizures.	CACNA1A SST	1.64e-05	3	82	2	23595603
Pubmed	Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.	PTPRD PTPRS	1.64e-05	3	82	2	20139422
Pubmed	Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.	PTPRD PTPRS	1.64e-05	3	82	2	9784606
Pubmed	Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.	PTPRD PTPRS	1.64e-05	3	82	2	33656439
Pubmed	Interaction of SH2-Bbeta with RET is involved in signaling of GDNF-induced neurite outgrowth.	RET GDNF	1.64e-05	3	82	2	16569669
Pubmed	Striatal GDNF Neurons Chemoattract RET-Positive Dopamine Axons at Seven Times Farther Distance Than Medium Spiny Neurons.	RET GDNF	1.64e-05	3	82	2	38920687
Pubmed	GDNF-RET signaling and EGR1 form a positive feedback loop that promotes tamoxifen resistance via cyclin D1.	RET GDNF	1.64e-05	3	82	2	36765275
Pubmed	GFRα1 released by nerves enhances cancer cell perineural invasion through GDNF-RET signaling.	RET GDNF	1.64e-05	3	82	2	24778213
Pubmed	Glial cell-line derived neurotrophic factor-mediated RET signaling regulates spermatogonial stem cell fate.	RET GDNF	1.64e-05	3	82	2	16237148
Pubmed	Selective chemical crosslinking reveals a Cep57-Cep63-Cep152 centrosomal complex.	CEP57 CEP63	1.64e-05	3	82	2	23333316
Pubmed	Functional interaction between the c-Abl and Arg protein-tyrosine kinases in the oxidative stress response.	ABL2 ABI2	1.64e-05	3	82	2	12569093
Pubmed	Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.	PTPRD PTPRS	1.64e-05	3	82	2	25394468
Pubmed	The structure of the glial cell line-derived neurotrophic factor-coreceptor complex: insights into RET signaling and heparin binding.	RET GDNF	1.64e-05	3	82	2	18845535
Pubmed	Biallelic variants in genes previously associated with dominant inheritance: CACNA1A, RET and SLC20A2.	CACNA1A RET	1.64e-05	3	82	2	34267336
Pubmed	Requirement of the Cep57-Cep63 Interaction for Proper Cep152 Recruitment and Centriole Duplication.	CEP57 CEP63	1.64e-05	3	82	2	32152252
Pubmed	Hirschsprung disease and congenital anomalies of the kidney and urinary tract (CAKUT): a novel syndromic association.	RET GDNF	1.64e-05	3	82	2	19282698
Pubmed	Glia cell line-derived neurotrophic factor regulates the distribution of acetylcholine receptors in mouse primary skeletal muscle cells.	RET GDNF	1.64e-05	3	82	2	15381279
Pubmed	Disturbances of colonic motility in mouse models of Hirschsprung's disease.	RET GDNF	1.64e-05	3	82	2	18276829
Pubmed	Sorting protein-related receptor SorLA controls regulated secretion of glial cell line-derived neurotrophic factor.	RET GDNF	1.64e-05	3	82	2	21994944
Pubmed	Evidence for a functional interaction between cingulin and ZO-1 in cultured cells.	CGN TJP2	1.64e-05	3	82	2	12023291
Pubmed	Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration.	RET GDNF	1.64e-05	3	82	2	25822020
Pubmed	Postsynaptic recruitment of Dendrin depends on both dendritic mRNA transport and synaptic anchoring.	MAGI1 DDN	1.64e-05	3	82	2	16464232
Pubmed	Prokineticin-1 (Prok-1) works coordinately with glial cell line-derived neurotrophic factor (GDNF) to mediate proliferation and differentiation of enteric neural crest cells.	RET GDNF	1.64e-05	3	82	2	18006159
Pubmed	The RET proto-oncogene induces apoptosis: a novel mechanism for Hirschsprung disease.	RET GDNF	1.64e-05	3	82	2	10921886
Pubmed	Arid1b haploinsufficiency in parvalbumin- or somatostatin-expressing interneurons leads to distinct ASD-like and ID-like behavior.	ARID1B SST	1.64e-05	3	82	2	32398858
Pubmed	Human and Xenopus cingulin share a modular organization of the coiled-coil rod domain: predictions for intra- and intermolecular assembly.	CGN TJP2	1.64e-05	3	82	2	11042084
Pubmed	Sympathoadrenal hyperplasia causes renal malformations in Ret(MEN2B)-transgenic mice.	RET GDNF	1.64e-05	3	82	2	10595945
Pubmed	Protein-tyrosine phosphatase SHP2 contributes to GDNF neurotrophic activity through direct binding to phospho-Tyr687 in the RET receptor tyrosine kinase.	RET GDNF	1.64e-05	3	82	2	20682772
Pubmed	Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis.	PRICKLE1 RET GDNF	1.88e-05	22	82	3	27582005
Pubmed	Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2.	MAGI1 MAGI2 ABL2	2.80e-05	25	82	3	23873930
Pubmed	Neural cells in the esophagus respond to glial cell line-derived neurotrophic factor and neurturin, and are RET-dependent.	RET GDNF	3.28e-05	4	82	2	15242795
Pubmed	Ret Signaling Is Required for Tooth Pulp Innervation during Organogenesis.	RET GDNF	3.28e-05	4	82	2	30958726
Pubmed	Upregulation of RET induces perineurial invasion of pancreatic adenocarcinoma.	RET GDNF	3.28e-05	4	82	2	28092668
Pubmed	A subpopulation of itch-sensing neurons marked by Ret and somatostatin expression.	RET SST	3.28e-05	4	82	2	26929027
Pubmed	Brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor are required simultaneously for survival of dopaminergic primary sensory neurons in vivo.	RET GDNF	3.28e-05	4	82	2	11160437
Pubmed	Crosstalk between VEGF-A/VEGFR2 and GDNF/RET signaling pathways.	RET GDNF	3.28e-05	4	82	2	17490619
Pubmed	Dominant effects of RET receptor misexpression and ligand-independent RET signaling on ureteric bud development.	RET GDNF	3.28e-05	4	82	2	10068631
Pubmed	Wnt5a-Ror2 signaling in mesenchymal stem cells promotes proliferation of gastric cancer cells by activating CXCL16-CXCR6 axis.	ROR2 CXCL16	3.28e-05	4	82	2	26708384
Pubmed	Regionalized loss of parvalbumin interneurons in the cerebral cortex of mice with deficits in GFRalpha1 signaling.	RET GDNF	3.28e-05	4	82	2	19710321
Pubmed	Localization and phosphorylation of Abl-interactor proteins, Abi-1 and Abi-2, in the developing nervous system.	ABL2 ABI2	3.28e-05	4	82	2	10995551
Pubmed	Implication of Wt1 in the pathogenesis of nephrogenic failure in a mouse model of retinoic acid-induced caudal regression syndrome.	RET GDNF	3.28e-05	4	82	2	15855632
Pubmed	Mutations in Hirschsprung disease: when does a mutation contribute to the phenotype.	RET GDNF	3.28e-05	4	82	2	9359036
Pubmed	SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.	RET GDNF	3.28e-05	4	82	2	23333276
Pubmed	Expression of GDNF and its receptors in developing tooth is developmentally regulated and suggests multiple roles in innervation and organogenesis.	RET GDNF	3.28e-05	4	82	2	9415430
Pubmed	Possible involvement of glial cell line-derived neurotrophic factor and its receptor, GFRalpha1, in survival and maturation of thymocytes.	RET GDNF	3.28e-05	4	82	2	12884298
Pubmed	The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.	PTPRD PTPRS	3.28e-05	4	82	2	8524829
Pubmed	Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development.	ROR2 AXIN2	3.28e-05	4	82	2	22771246
Pubmed	Trans-mesenteric neural crest cells are the principal source of the colonic enteric nervous system.	RET GDNF	3.28e-05	4	82	2	22902718
Pubmed	Cingulin contains globular and coiled-coil domains and interacts with ZO-1, ZO-2, ZO-3, and myosin.	CGN TJP2	3.28e-05	4	82	2	10613913
Pubmed	Analysis of RET, ZEB2, EDN3 and GDNF genomic rearrangements in 80 patients with Hirschsprung disease (using multiplex ligation-dependent probe amplification).	RET GDNF	3.28e-05	4	82	2	19183406
Pubmed	Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche.	RET GDNF	3.28e-05	4	82	2	20855470
Pubmed	Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene.	RET GDNF	3.28e-05	4	82	2	11731455
Pubmed	Glial cell line-derived neurotrophic factor induces cell proliferation in the mouse urogenital sinus.	RET GDNF	3.28e-05	4	82	2	25549043
Interaction	YWHAH interactions	STK3 DOCK4 MAGI1 ABL2 FAM171A2 SYNJ1 ABI2 ROR2 CGN TJP2 FLCN NHS PFKFB2 STIL CDC25B TAB3	5.64e-06	1102	80	16	int:YWHAH
Interaction	MAGI1 interactions	MAGI1 ATF6 CGN DDN TJP2 CDC25B	2.62e-05	147	80	6	int:MAGI1
Interaction	CGN interactions	MAGI1 CGN TJP2 STIL CDC25B MYO5C	3.16e-05	152	80	6	int:CGN
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	MAGI1 MAGI2 TJP2	5.25e-05	26	51	3	904
GeneFamily	PDZ domain containing	MAGI1 MAGI2 TJP2 APBA3	8.83e-04	152	51	4	1220
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	PTPRD PTPRS ROR2 ADGRF5	1.09e-03	161	51	4	593
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRD PTPRS	1.58e-03	21	51	2	813
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#1_top-relative-expression-ranked_500	ABI2 ROR2 CDC6 FIGN GDNF	2.30e-05	89	81	5	gudmap_developingKidney_e15.5_Peripheral blastema_500_k1
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	STK3 MAGI1 MAGI2 ARID1B PTPRD GLIS3 NHS	6.70e-08	192	82	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	STK3 DOCK4 MAGI1 MAGI2 ARID1B PTPRD GLIS3	8.27e-08	198	82	7	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	MAGI1 NTN4 PTPRD GLIS3 ADGRF5 MYO5C	1.20e-06	185	82	6	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ATRNL1 ROR2 MAMLD1 GLIS3 NHS TNS1	1.28e-06	187	82	6	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NTN4 PTPRD PRICKLE1 GLIS3 NHS FIGN	1.41e-06	190	82	6	989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NTN4 PTPRD PRICKLE1 GLIS3 NHS FIGN	1.45e-06	191	82	6	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	MAGI1 NTN4 ADGRF5 PFKFB2 MUCL3 MYO5C	1.49e-06	192	82	6	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK4 MAGI2 PTPRS ROR2 MAMLD1 TNS1	1.59e-06	194	82	6	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAGI2 PTPRD PTPRS ROR2 GLIS3 NHS	1.59e-06	194	82	6	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ATRNL1 ROR2 MAMLD1 GLIS3 NHS FIGN	1.63e-06	195	82	6	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	STK3 DOCK4 MAGI1 MAGI2 ARID1B PTPRD	1.68e-06	196	82	6	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	MAGI2 PTPRD PRICKLE1 ROR2 GLIS3 NHS	1.73e-06	197	82	6	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	BAL-Control-cDC_12\|Control / Compartment, Disease Groups and Clusters	CACNA1A FAM171A2 STIL CDC6 CDC7	9.71e-06	154	82	5	0121d08cc527aed9b3e11ff62bb9012916f5c56b
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	DOCK4 PTPRD PTPRS MARCHF3 TNS1	1.32e-05	164	82	5	519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell	Control\|World / group, cell type (main and fine annotations)	MAGI1 NTN4 CGN ADGRF5 MYO5C	1.48e-05	168	82	5	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	STK3 ATF6 PTPRD PTPRS TNS1	1.48e-05	168	82	5	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	DOCK4 MAGI1 ADGRF5 TNS1 MYO5C	1.57e-05	170	82	5	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	DOCK4 MAGI1 CGN TNS1 MYO5C	1.75e-05	174	82	5	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MAGI2 ATRNL1 GLIS3 NHS SST	1.95e-05	178	82	5	544379f5a6145429762258d426b876bb36c112f5
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	SYNJ1 EFS PCDHAC2 RET SST	2.01e-05	179	82	5	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 MAGI2 PTPRD GLIS3 NHS	2.06e-05	180	82	5	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	NTN4 ADGRF5 PFKFB2 MUCL3 MYO5C	2.29e-05	184	82	5	0ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	NTN4 ADGRF5 PFKFB2 MUCL3 MYO5C	2.29e-05	184	82	5	2a8338e94937686a148b5433515700ca0f674058
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	MAGI2 PTPRS MARCHF3 ROR2 GLIS3	2.35e-05	185	82	5	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CGN PFKFB2 RET GDNF MYO5C	2.54e-05	188	82	5	b1049003ca79c340bb8c78da66bdc0956e1aebc2
ToppCell	facs-Lung-EPCAM-3m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CGN PFKFB2 RET GDNF MYO5C	2.54e-05	188	82	5	3dd571bd8e7358b4346dea71f6bf9602dabf583c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRD PRICKLE1 NHS FIGN TNS1	2.60e-05	189	82	5	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRD PTPRS ROR2 GLIS3 NHS	2.60e-05	189	82	5	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MARCHF3 ROR2 GLIS3 NHS CDC7	2.67e-05	190	82	5	0fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MARCHF3 ROR2 MAMLD1 GLIS3 NHS	2.74e-05	191	82	5	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 NTN4 PTPRD ADGRF5 MYO5C	2.74e-05	191	82	5	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	facs-Lung-EPCAM-3m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CGN PFKFB2 RET GDNF MYO5C	2.74e-05	191	82	5	629007189034ee8451411428f1c6cc57daee2d91
ToppCell	Control-Epithelial-Club\|Control / Disease state, Lineage and Cell class	MAGI1 NTN4 GLIS3 NHS ADGRF5	2.81e-05	192	82	5	d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NTN4 ADGRF5 PFKFB2 MUCL3 MYO5C	2.81e-05	192	82	5	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAGI2 PTPRD ROR2 GLIS3 NHS	2.81e-05	192	82	5	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK4 MAGI2 PTPRS ROR2 MAMLD1	2.88e-05	193	82	5	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAGI2 PTPRD ROR2 GLIS3 NHS	2.88e-05	193	82	5	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI2 PTPRS ROR2 MAMLD1 FIGN	2.88e-05	193	82	5	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 NTN4 CGN ADGRF5 MYO5C	2.88e-05	193	82	5	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK4 MARCHF3 HLA-E ADGRF5 TNS1	2.88e-05	193	82	5	479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRS ATRNL1 ROR2 MAMLD1 FIGN	2.95e-05	194	82	5	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	cellseq2-Epithelial-Epithelial_Alveolar-AT2-AT2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	STK3 NTN4 ADGRF5 CDC6 TNS1	2.95e-05	194	82	5	df835578d86a49ae5af5632152fbab9548c0a448
ToppCell	PND01-03-samps-Mesenchymal\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	DOCK4 PTPRD PTPRS TNS1 AXIN2	2.95e-05	194	82	5	4f9bd0ded0dde1df885850714f29e73e992539a5
ToppCell	cellseq2-Epithelial-Epithelial_Alveolar\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	STK3 NTN4 ADGRF5 CDC6 TNS1	2.95e-05	194	82	5	0715f2d55f4a6d2edda1b3dc52f12d25ce59eb10
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAGI2 PTPRD PTPRS ROR2 GLIS3	2.95e-05	194	82	5	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAGI2 PTPRD ROR2 GLIS3 NHS	2.95e-05	194	82	5	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	cellseq2-Epithelial-Epithelial_Alveolar-AT2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	STK3 NTN4 ADGRF5 CDC6 TNS1	2.95e-05	194	82	5	a4f7cd507eba40985d82635bbae28c7f5703f883
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRS ATRNL1 ROR2 MAMLD1 FIGN	2.95e-05	194	82	5	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A KMT2C SYNJ1 PFKFB2 RET	3.02e-05	195	82	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KMT2C ABL2 MAMLD1 NCF4 TNS1	3.33e-05	199	82	5	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-CHRNA4-L1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	MAGI2 NTN4 MARCHF3 HLA-E SST	3.41e-05	200	82	5	e2ced6eb1de9a526c34c7558b9c637854916e624
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-CHRNA4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	MAGI2 NTN4 MARCHF3 HLA-E SST	3.41e-05	200	82	5	9bc924755e5a4c464408e6103b86bf1b4e8c58b5
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ABL2 MARCHF3 CXCL16 GDNF	4.58e-05	107	82	4	13af691c8533418d2800a8eca61155896b559948
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ABL2 MARCHF3 CXCL16 GDNF	4.58e-05	107	82	4	a5a34bb9706527799ddb494d4f1bfc634c29e8a9
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Interneuron\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	STIL SST FIGN SLC25A45	7.40e-05	121	82	4	b2d571f571133c281d72584fe925cebbd2317829
ToppCell	COVID-19_Severe-Classical_Monocyte-\|COVID-19_Severe / Disease condition and Cell class	PRICKLE1 LMNTD2 ADGRF5 CDC7	1.30e-04	140	82	4	cade44740dd3acca7789591aa5a7935d48d5cbee
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATRNL1 MAMLD1 RET GDNF	1.49e-04	145	82	4	051d964ff6bdc12ba3f0459d3e6ab16fa9507b0b
ToppCell	facs-Lung-18m-Hematologic-myeloid-leukocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CGN STIL TAB3 SLC25A45	1.83e-04	153	82	4	8cc2667213bfac37545bb63181e88ef1f1834413
ToppCell	facs-Lung-18m-Hematologic-myeloid-leukocyte-proliferating_myeloid_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CGN STIL TAB3 SLC25A45	1.83e-04	153	82	4	596bb7cfd1c713708ce73df30d890a0233eae7f7
ToppCell	PND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CORO2A CDC6 SOAT2 SLC25A45	1.92e-04	155	82	4	4ae91bc7dbb9f713a1f110c17834b1d89f1b28db
ToppCell	PND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CORO2A CDC6 SOAT2 SLC25A45	1.92e-04	155	82	4	fdcc8a475156329b3594d5ed22ba03538305327c
ToppCell	PND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CORO2A CDC6 SOAT2 SLC25A45	1.92e-04	155	82	4	1fb49b48e34e740118908951e079ea2a9994ae4f
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAM111A NCF4 CDC6 CDC7	1.97e-04	156	82	4	6f8622716bad4e505f241a2a4ef953bf3fc6dbfa
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-AT1_Progenitor\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTN4 NCF4 PFKFB2 SOAT2	2.02e-04	157	82	4	a93866f051472506f1468f379c0d5313e02c9731
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-CD45____NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CORO2A STIL SOAT2 WDR47	2.33e-04	163	82	4	a763c1632d6465a1e753bdc8eadaf819d2b09e5e
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CORO2A STIL SOAT2 WDR47	2.33e-04	163	82	4	eaed783eecd07aafa5af844b63c9d816b4da99e4
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-GABAergic_neurons\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	NTN4 ATRNL1 PCDHAC2 SST	2.39e-04	164	82	4	4d7b2d0980fb4f47721fa2891151e2bd892ccb91
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A GLIS3 STIL MYO5C	2.39e-04	164	82	4	d6f71d804bb65301c02ea4e6673e20688b5fcd5b
ToppCell	control-Epithelial-Ionocyte\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DOCK4 ENAM ADGRF5 RET	2.44e-04	165	82	4	5cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNS1 SOAT2 AXIN2 WDR47	2.50e-04	166	82	4	aa2df07eff323ded751ced8938af08223d7f2029
ToppCell	NS-control-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DOCK4 ENAM ADGRF5 RET	2.50e-04	166	82	4	6d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNS1 SOAT2 AXIN2 WDR47	2.50e-04	166	82	4	695298a94d62b8adab083900003ec636fbaae5d9
ToppCell	facs-Aorta-Heart-24m-Myeloid-leukocyte\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CORO2A CDC6 SOAT2 TAB3	2.56e-04	167	82	4	b85fd7ab21c80470bca804c788ce49a2bce763f8
ToppCell	Control-Myeloid-MoAM1,_IL1R2\|Control / Condition, Lineage and Cell class	DOCK4 MAGI2 SAMD9 PRICKLE1	2.56e-04	167	82	4	ab6029ba037b6a499da8758864c44e174cde5587
ToppCell	Control-Myeloid-MoAM1,_IL1R2\|Myeloid / Condition, Lineage and Cell class	DOCK4 MAGI2 SAMD9 PRICKLE1	2.56e-04	167	82	4	6e5140527437193f441ca96893b9a00d346614f3
ToppCell	control-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DOCK4 ENAM ADGRF5 RET	2.61e-04	168	82	4	327b02f19f4a8607c033203824fdc60a1254331f
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MAGI2 ATRNL1 GLIS3 NHS	2.61e-04	168	82	4	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAM171A2 PRICKLE1 SERINC3 ADGRF5	2.67e-04	169	82	4	41ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCell	343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	FAM171A2 ATRNL1 STIL CDC6	2.67e-04	169	82	4	a949f547b53126a208819bade74a1ac9b2a36ea7
ToppCell	343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	FAM171A2 ATRNL1 STIL CDC6	2.67e-04	169	82	4	195d5cd60d646ac6d40a3321b2f739917e7aef14
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAM171A2 PRICKLE1 SERINC3 ADGRF5	2.67e-04	169	82	4	42782c61592742190ab0cba8a94f8bdf9c278f90
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	PRICKLE1 ATRNL1 FIGN TNS1	2.86e-04	172	82	4	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 NTN4 HLA-E ADGRF5	2.92e-04	173	82	4	f193c63cc536d891c9d23043765e320252bb6e65
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM111A SERINC3 SST SOAT2	2.92e-04	173	82	4	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 HLA-E ADGRF5 NDUFB8	2.92e-04	173	82	4	afa6bb19df52541d8d17cbfac9cbdd18a5f3632d
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM111A SERINC3 SST SOAT2	2.92e-04	173	82	4	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM111A SERINC3 SST SOAT2	2.92e-04	173	82	4	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAM111A ADGRF5 CDC6 CDC7	2.99e-04	174	82	4	c988471207ba06195bc3e41056435e8c31c20bbe
ToppCell	Bronchial_Biopsy-Epithelial-Ionocytes\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	ENAM ADGRF5 RET SST	2.99e-04	174	82	4	7e7b13de916cd4fa0fa6fb06e6b4942877afa9fb
ToppCell	COPD-Myeloid-pDC\|World / Disease state, Lineage and Cell class	ENAM PTPRS PFKFB2 RET	2.99e-04	174	82	4	be8227398300711ccda5ecc41ad34064bb246b19
ToppCell	COVID-19-kidney-REN+Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1A NHS RET FIGN	2.99e-04	174	82	4	8393f0b43c767839c1630bcb952d62b42efc788d
ToppCell	mild_COVID-19-pDC\|mild_COVID-19 / disease group, cell group and cell class (v2)	PTPRS CGN PFKFB2 RET	3.05e-04	175	82	4	b87f279a7519710146c49d6acccb0adedc195965
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ATRNL1 GLIS3 SST CDC6	3.05e-04	175	82	4	910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCell	Bronchial_Biopsy-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ENAM ADGRF5 RET SST	3.05e-04	175	82	4	13b8f7dc38c90b74d4a20a84a8705d8e2ec244f6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ATRNL1 GLIS3 SST CDC6	3.05e-04	175	82	4	f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCell	NS-moderate-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ENAM ELMO2 ADGRF5 RET	3.05e-04	175	82	4	a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCell	IPF-Myeloid-pDC\|World / Disease state, Lineage and Cell class	ENAM PTPRS PFKFB2 RET	3.05e-04	175	82	4	a06785a4ded01adfd29ca4c20f7759eccbe274cb
ToppCell	P03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MAGI1 CGN CXCL16 TNS1	3.12e-04	176	82	4	f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCell	severe-Myeloid-Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	DOCK4 HLA-E NHS CXCL16	3.19e-04	177	82	4	d1ad35ee3d2a84b1d01126d0a38464ab858c00d0
ToppCell	Control-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	ENAM PTPRS PFKFB2 RET	3.19e-04	177	82	4	e82115bfc32c7b689460fbc5caeb983c1aabe30f
Drug	Diethylcarbamazine citrate [1642-54-2]; Down 200; 10.2uM; HL60; HT_HG-U133A	FBXL18 ABI2 OGFR DDN FLCN RET RAB5B	7.41e-06	198	82	7	2394_DN
Drug	Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; PC3; HT_HG-U133A	CACNA1A FBXL18 PPRC1 ELMO2 OGFR PFKFB2 TNS1	7.66e-06	199	82	7	4294_DN
Disease	autosomal recessive Robinow syndrome (implicated_via_orthology)	PRICKLE1 ROR2	7.44e-06	2	81	2	DOID:0060764 (implicated_via_orthology)
Disease	cholesteryl ester 17:0 measurement	MAGI1 SOAT2	2.23e-05	3	81	2	EFO_0021436
Disease	CCHS WITH HIRSCHSPRUNG DISEASE	RET GDNF	7.40e-05	5	81	2	C1859049
Disease	Hirschsprung Disease	ARID1B RET GDNF	8.47e-05	31	81	3	C0019569
Disease	Aganglionic megacolon	RET GDNF	1.11e-04	6	81	2	cv:C0019569
Disease	Adenocarcinoma of large intestine	ROR2 FLCN RET AXIN2	1.44e-04	96	81	4	C1319315
Disease	Congenital central hypoventilation	RET GDNF	1.55e-04	7	81	2	C1275808
Disease	N6,N6-dimethyllysine measurement	PPRC1 SLC25A45	2.65e-04	9	81	2	EFO_0800100
Disease	pursuit maintenance gain measurement	MAGI2 PTPRD SPATA31C2 SST	3.73e-04	123	81	4	EFO_0008433
Disease	Hirschsprung's disease (is_implicated_in)	RET GDNF	4.03e-04	11	81	2	DOID:10487 (is_implicated_in)
Disease	endometrial carcinoma, endometriosis	PTPRD AXIN2	4.03e-04	11	81	2	EFO_0001065, EFO_1001512
Disease	Hirschsprung's disease (implicated_via_orthology)	RET GDNF	4.83e-04	12	81	2	DOID:10487 (implicated_via_orthology)
Disease	cannabis dependence	CACNA1A MAGI2 NOL4L PTPRD	5.31e-04	135	81	4	EFO_0007191
Disease	Aganglionosis, Rectosigmoid Colon	RET GDNF	7.64e-04	15	81	2	C1257840
Disease	Aganglionosis, Colonic	RET GDNF	7.64e-04	15	81	2	C0085758
Disease	cancer (implicated_via_orthology)	STK3 ARID1B RET RAB5B AXIN2	8.69e-04	268	81	5	DOID:162 (implicated_via_orthology)
Disease	Pheochromocytoma, Extra-Adrenal	RET GDNF	8.71e-04	16	81	2	C1257877
Disease	congenital heart disease (implicated_via_orthology)	KMT2C SAP130 AXIN2	9.16e-04	69	81	3	DOID:1682 (implicated_via_orthology)
Disease	Parkinson's disease (implicated_via_orthology)	SYNJ1 PPRC1 COX10 AXIN2	9.34e-04	157	81	4	DOID:14330 (implicated_via_orthology)
Disease	MAJOR AFFECTIVE DISORDER 2	MAGI1 MAGI2	9.85e-04	17	81	2	C1839839
Disease	Congenital Intestinal Aganglionosis	RET GDNF	9.85e-04	17	81	2	C3661523
Disease	Pheochromocytoma	RET GDNF	1.23e-03	19	81	2	C0031511
Disease	Lung diseases	FLCN RET GDNF	1.31e-03	78	81	3	C0024115
Disease	severe acute respiratory syndrome, COVID-19	MAGI1 MAGI2 NTN4 PTPRD MAMLD1 CEP57	1.46e-03	447	81	6	EFO_0000694, MONDO_0100096
Disease	Primary microcephaly	STIL CEP63	1.66e-03	22	81	2	C0431350
Disease	Autosomal Recessive Primary Microcephaly	STIL CEP63	1.66e-03	22	81	2	C3711387
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	RET GDNF	1.81e-03	23	81	2	C1708353
Disease	Bipolar Disorder	CACNA1A MAGI1 MAGI2 HLA-E SST GDNF	2.02e-03	477	81	6	C0005586
Disease	response to peginterferon alfa-2a	CORO2A GLIS3	2.14e-03	25	81	2	EFO_0010103
Disease	Colorectal cancer	FLCN AXIN2	2.50e-03	27	81	2	cv:C0346629
Disease	COLORECTAL CANCER	FLCN AXIN2	2.50e-03	27	81	2	114500
Disease	Neoplasm of the large intestine	FLCN AXIN2	2.50e-03	27	81	2	cv:C0009404
Disease	azoospermia (implicated_via_orthology)	PTPRD PTPRS	2.50e-03	27	81	2	DOID:14227 (implicated_via_orthology)
Disease	neuroimaging measurement	MAGI1 SAMD9 SYNJ1 EFS ROR2 GLIS3 PFKFB2 CEP57 TNS1	2.62e-03	1069	81	9	EFO_0004346
Disease	Adenoid Cystic Carcinoma	MAGI1 MAGI2 KMT2C	2.66e-03	100	81	3	C0010606

Protein segments in the cluster

Peptide	Gene	Start	Entry
RRQSQMDAASTRAPP	nan	6	A8MWP4
AMATNPQNAASRRTP	CACNA1A	1111	O00555
NQTPVRMRRNSFTPL	PFKFB2	456	O60825
PKRSSSFREMENQPH	ABL2	666	P42684
LVSERNPPTSTRMAQ	APBA3	231	O96018
NSFAEPSRSNGSMVR	CEP57	16	Q86XR8
EVPFDSNMNRTKNRP	COX10	211	Q12887
TKPMPVSSNTRRNED	AXIN2	46	Q9Y2T1
SDSPPSVQFMNRLRK	CXCL16	46	Q9H2A7
PASFQRSLENRMSPS	ARID1B	1626	Q8NFD5
DSRRMNPSVSPANQR	ATF6	401	P18850
QRDSQTGMANPFRDP	DET1	276	Q7L5Y6
PRSAQQPVLFSLMNS	C5orf52	61	A6NGY3
SRRAPSRQPMDFQAS	DDN	46	O94850
MAPSQQSPVRTASVN	ABI2	221	Q9NYB9
MTSRSTARPNGQPQA	RAB5B	1	P61020
QNLRSQAPMFRPDTT	PATL1	341	Q86TB9
QRSTQSPMYRMPDNS	FIGN	341	Q5HY92
RFDNDAASPRMVPRA	HLA-E	56	P13747
RSVSVDMPRPLNNSQ	KMT2C	2516	Q8NEZ4
AQSRSMYENRPMSPS	MAGI1	796	Q96QZ7
RQQVPPRTSFRMDSS	MAGI2	756	Q86UL8
PQRAQRMNTAFTPFL	FLCN	216	Q8NFG4
DNIQTAFNTRMPPRS	INTS1	251	Q8N201
SPQGNSVDRMAAPRA	NCF4	161	Q15080
REAFAQRPSSAPDLM	CDC25B	221	P30305
RRAPFALSSDSNMPE	GDNF	41	P39905
ARRYPNLFTNMEPSS	LMNTD2	221	Q8IXW0
MYNRNRVDTSPTPVS	NDUFB8	111	O95169
SLSPSQDERMRSPQN	NOL4L	16	Q96MY1
PASAPRNVQARMLSA	PTPRS	426	Q13332
LTPASTQQEMRAFPA	FAM171A2	176	A8MVW0
NSSAAFEMVPRTAPA	PCDHAC2	586	Q9Y5I4
SLFQPQPNEMDIRAS	PRICKLE1	426	Q96MT3
NPNDPRARMDSESLF	GMPPA	361	Q96IJ6
RPQPSSSAMRFQFQD	DOCK4	896	Q8N1I0
RQSERMSQDDFQSPP	ELMO2	511	Q96JJ3
EPMAFSPQRDRFQAE	CDC7	11	O00311
PRGQASDSINPMSRV	CEP63	581	Q96MT8
RMVPSAAASQNPESE	FAM111A	271	Q96PZ2
MNAANLNIPPSDTRS	GLIS3	31	Q8NEA6
FNSMAPASPRLLNQT	CORO2A	416	Q92828
RQQMASRPFASVDVA	ATRNL1	1271	Q5VV63
MPQTRSQAQATISFP	CDC6	1	Q99741
ALMSSTQANQPPRLF	EFS	456	O43281
PLPQQMRVAFSAART	CAPRIN2	991	Q6IMN6
PQRFQRSVASDSMPA	MAMLD1	621	Q13495
VRTLATQSPFNDRPM	MARCHF3	56	Q86UD3
TRMNSPEREHSSFPN	ENAM	836	Q9NRM1
RPDRQTVMFSATFPR	DDX46	551	Q7L014
LSPEASPCRNDMNTR	PPRC1	1376	Q5VV67
DPMIRNQRSVDPADS	MUCL3	131	Q3MIW9
APSSAPRDVQARMLS	PTPRD	416	P23468
QNPSSFDPSMLLQRF	RNF180	281	Q86T96
EEPRAARPSSFQSRM	OGFR	46	Q9NZT2
QRDTTMSPLLFQAQP	SPATA31C2	311	B4DYI2
FMNEQNRSAATPPSQ	TAB3	141	Q8N5C8
ARSQSQENMRSSPNP	SYNJ1	1381	O43426
PLDFANTPSRMENAN	NHS	891	Q6T4R5
SPRPAAMVLDRSQDF	NTN4	136	Q9HB63
MRSQNPEKSARIPDS	SAMD9	836	Q5K651
SSAMPRNEPAIRNSL	FBXL18	496	Q96ME1
ASTPQRRQLMASPSQ	ROR2	436	Q01974
MNNQARTPAPSSART	SELENOV	1	P59797
PVFANMSREPFSTRA	SOAT2	321	O75908
PVFSMSSPISRRFNN	ADGRF5	1301	Q8IZF2
SFEEPRRSAQDPTML	CGN	276	Q9P2M7
RPQSADAYMTRSLNP	WDR47	301	O94967
PFARPQMNTRFPSSR	STIL	6	Q15468
RNATSPQVQRPSFMD	STK3	381	Q13188
SPEPRAQMRRAASSD	TJP2	966	Q9UDY2
AIAPFRSSRVPNDDM	nan	126	Q6ZSR9
ATSHQERRAQPPSYM	SLC25A45	86	Q8N413
EQPTMCTSLRAPARN	SMRP1	231	Q8NCR6
METRSDNRPSVPVQF	SAP130	471	Q9H0E3
MFRSQSFSEAEPQLP	TNS1	616	Q9HBL0
PDRSCNPNLMSFITR	SERINC3	291	Q13530
SAEMTFRRPAQAFPV	RET	671	P07949
PAADTRRAEMSQTNF	ZNF507	96	Q8TCN5
ADRSPSLSVAPQDRM	TASOR2	216	Q5VWN6
FNRSPLTMDQIRPNT	UBE4A	1031	Q14139
RSNSPFPSRVFMDSN	TCTN3	141	Q6NUS6
LQRSANSNPAMAPRE	SST	86	P61278
VARAQPQTMFPSASE	PP6455	31	Q8WZ26
MAAARPEAQSRSSPT	ZNF784	1	Q8NCA9
NRNPLFEKPRMSNTS	MYO5C	531	Q9NQX4