Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin binding	EPS8 DST NEBL AFDN DMD NEB ADD1 ADD2	8.86e-05	479	60	8	GO:0003779
GeneOntologyMolecularFunction	structural constituent of muscle	NEBL DMD NEB	2.92e-04	43	60	3	GO:0008307
GeneOntologyMolecularFunction	actin filament binding	NEBL AFDN NEB ADD1 ADD2	5.97e-04	227	60	5	GO:0051015
GeneOntologyMolecularFunction	G protein activity	RAP2A RAP2B RAP2C	7.44e-04	59	60	3	GO:0003925
GeneOntologyBiologicalProcess	positive regulation of protein autophosphorylation	RAP2A RAP2B NBN RAP2C	1.45e-06	29	60	4	GO:0031954
GeneOntologyBiologicalProcess	endothelial cell development	RAP2B AFDN DMD RAP2C ADD1	3.57e-06	80	60	5	GO:0001885
GeneOntologyBiologicalProcess	Rap protein signal transduction	RAP2A RAP2B RAP2C	8.33e-06	14	60	3	GO:0032486
GeneOntologyBiologicalProcess	regulation of protein autophosphorylation	RAP2A RAP2B NBN RAP2C	9.63e-06	46	60	4	GO:0031952
GeneOntologyBiologicalProcess	establishment of endothelial intestinal barrier	RAP2B AFDN RAP2C	1.55e-05	17	60	3	GO:0090557
GeneOntologyBiologicalProcess	establishment of endothelial barrier	RAP2B AFDN RAP2C ADD1	2.44e-05	58	60	4	GO:0061028
GeneOntologyBiologicalProcess	cardiac muscle thin filament assembly	NEBL NEB	2.49e-05	3	60	2	GO:0071691
GeneOntologyBiologicalProcess	microvillus assembly	RAP2A RAP2B RAP2C	7.28e-05	28	60	3	GO:0030033
GeneOntologyBiologicalProcess	barbed-end actin filament capping	EPS8 ADD1 ADD2	8.10e-05	29	60	3	GO:0051016
GeneOntologyBiologicalProcess	endothelial cell differentiation	RAP2B AFDN DMD RAP2C ADD1	9.62e-05	158	60	5	GO:0045446
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection assembly	VANGL2 EPS8 EXOC5 RAP2A RAP2B TTC21B CFAP57 RAP2C DNMBP	1.28e-04	670	60	9	GO:0120031
GeneOntologyBiologicalProcess	microvillus organization	RAP2A RAP2B RAP2C	1.31e-04	34	60	3	GO:0032528
GeneOntologyBiologicalProcess	cell projection assembly	VANGL2 EPS8 EXOC5 RAP2A RAP2B TTC21B CFAP57 RAP2C DNMBP	1.52e-04	685	60	9	GO:0030031
GeneOntologyBiologicalProcess	endothelium development	RAP2B AFDN DMD RAP2C ADD1	1.87e-04	182	60	5	GO:0003158
GeneOntologyBiologicalProcess	actin filament-based process	VANGL2 CDC42BPG EPS8 RAP2A NEBL SCN4A RACGAP1 NEB ADD1 ADD2	2.75e-04	912	60	10	GO:0030029
GeneOntologyBiologicalProcess	adherens junction maintenance	AFDN PLEKHA7	2.96e-04	9	60	2	GO:0034334
GeneOntologyBiologicalProcess	actin filament capping	EPS8 ADD1 ADD2	3.25e-04	46	60	3	GO:0051693
GeneOntologyBiologicalProcess	choline transport	SLC22A2 SCN4A	3.69e-04	10	60	2	GO:0015871
GeneOntologyBiologicalProcess	negative regulation of actin filament depolymerization	EPS8 ADD1 ADD2	4.67e-04	52	60	3	GO:0030835
GeneOntologyBiologicalProcess	actin cytoskeleton organization	VANGL2 CDC42BPG EPS8 RAP2A NEBL RACGAP1 NEB ADD1 ADD2	4.89e-04	803	60	9	GO:0030036
GeneOntologyBiologicalProcess	protein autophosphorylation	STK10 RAP2A RAP2B NBN RAP2C	5.26e-04	228	60	5	GO:0046777
GeneOntologyCellularComponent	postsynaptic density	VANGL2 EPS8 DST AFDN DMD ADD1 ADD2 ITPR1	2.89e-05	451	57	8	GO:0014069
GeneOntologyCellularComponent	asymmetric synapse	VANGL2 EPS8 DST AFDN DMD ADD1 ADD2 ITPR1	4.29e-05	477	57	8	GO:0032279
GeneOntologyCellularComponent	postsynaptic specialization	VANGL2 EPS8 DST AFDN DMD ADD1 ADD2 ITPR1	6.24e-05	503	57	8	GO:0099572
GeneOntologyCellularComponent	neuron to neuron synapse	VANGL2 EPS8 DST AFDN DMD ADD1 ADD2 ITPR1	8.19e-05	523	57	8	GO:0098984
GeneOntologyCellularComponent	cell-cell contact zone	RAP2B DST AFDN RAP2C	1.26e-04	94	57	4	GO:0044291
GeneOntologyCellularComponent	synaptic membrane	VANGL2 RAP2A SLC22A2 AFDN DMD CNR1 GPR179 ITPR1	1.73e-04	583	57	8	GO:0097060
GeneOntologyCellularComponent	cell-cell junction	VANGL2 RAP2B DST AFDN RAP2C DNMBP PLEKHA7 ADD1	1.90e-04	591	57	8	GO:0005911
GeneOntologyCellularComponent	F-actin capping protein complex	ADD1 ADD2	2.60e-04	9	57	2	GO:0008290
GeneOntologyCellularComponent	secretory granule	PCSK2 STK10 RAP2B SCG2 UBR4 APAF1 RACGAP1 DMD RAP2C ITPR1	3.73e-04	1014	57	10	GO:0030141
GeneOntologyCellularComponent	postsynapse	VANGL2 RPL24 EPS8 DST AFDN DMD GPR179 ADD1 ADD2 ITPR1	3.85e-04	1018	57	10	GO:0098794
GeneOntologyCellularComponent	secretory vesicle	PCSK2 STK10 RAP2B SCG2 SLC22A2 UBR4 APAF1 RACGAP1 DMD RAP2C ITPR1	4.72e-04	1246	57	11	GO:0099503
GeneOntologyCellularComponent	Z disc	DST NEBL DMD NEB	7.68e-04	151	57	4	GO:0030018
GeneOntologyCellularComponent	apical junction complex	RAP2B AFDN RAP2C PLEKHA7	9.09e-04	158	57	4	GO:0043296
GeneOntologyCellularComponent	actin cytoskeleton	VANGL2 DST NEBL NEB CNR1 ADD1 ADD2	9.32e-04	576	57	7	GO:0015629
GeneOntologyCellularComponent	tertiary granule membrane	RAP2B UBR4 RAP2C	1.04e-03	73	57	3	GO:0070821
GeneOntologyCellularComponent	I band	DST NEBL DMD NEB	1.09e-03	166	57	4	GO:0031674
GeneOntologyCellularComponent	anchoring junction	VANGL2 RAP2B DST AFDN DMD RAP2C DNMBP PLEKHA7 ADD1	1.21e-03	976	57	9	GO:0070161
GeneOntologyCellularComponent	cell pole	VANGL2 GPR179	1.34e-03	20	57	2	GO:0060187
GeneOntologyCellularComponent	specific granule membrane	STK10 RAP2B UBR4	1.97e-03	91	57	3	GO:0035579
GeneOntologyCellularComponent	secretory granule membrane	STK10 RAP2B UBR4 RAP2C ITPR1	2.01e-03	329	57	5	GO:0030667
GeneOntologyCellularComponent	pore complex	AFDN PLEKHA7	2.28e-03	26	57	2	GO:0046930
GeneOntologyCellularComponent	contractile actin filament bundle	VANGL2 DST NEBL	3.12e-03	107	57	3	GO:0097517
GeneOntologyCellularComponent	stress fiber	VANGL2 DST NEBL	3.12e-03	107	57	3	GO:0001725
GeneOntologyCellularComponent	recycling endosome membrane	RAP2A RAP2B RAP2C	3.55e-03	112	57	3	GO:0055038
GeneOntologyCellularComponent	actomyosin	VANGL2 DST NEBL	4.01e-03	117	57	3	GO:0042641
GeneOntologyCellularComponent	actin filament bundle	VANGL2 DST NEBL	4.11e-03	118	57	3	GO:0032432
GeneOntologyCellularComponent	sarcomere	DST NEBL DMD NEB	4.73e-03	249	57	4	GO:0030017
MousePheno	abnormal muscle electrophysiology	DST SCN4A DMD NEB	4.84e-06	32	50	4	MP:0004145
MousePheno	impaired skeletal muscle contractility	DST SCN4A DMD NEB	1.77e-05	44	50	4	MP:0002841
MousePheno	kinked tail	VANGL2 RPL24 DST KIAA1217 APAF1	5.22e-05	114	50	5	MP:0000585
MousePheno	impaired muscle relaxation	NEBL SCN4A DMD	1.32e-04	28	50	3	MP:0003157
MousePheno	persistence of hyaloid vascular system	VANGL2 RPL24 NCOR2 DST APAF1 PTPN18	1.36e-04	223	50	6	MP:0001289
Domain	NEBU	NEBL NEB	5.66e-05	4	58	2	SM00227
Domain	Nebulin	NEBL NEB	5.66e-05	4	58	2	PF00880
Domain	Nebulin	NEBL NEB	5.66e-05	4	58	2	IPR013998
Domain	Aldolase_II/adducin_N	ADD1 ADD2	5.66e-05	4	58	2	IPR001303
Domain	Aldolase_II	ADD1 ADD2	5.66e-05	4	58	2	PF00596
Domain	NEBULIN	NEBL NEB	5.66e-05	4	58	2	PS51216
Domain	Nebulin_repeat	NEBL NEB	5.66e-05	4	58	2	IPR000900
Domain	-	ADD1 ADD2	5.66e-05	4	58	2	3.40.225.10
Domain	Aldolase_II	ADD1 ADD2	5.66e-05	4	58	2	SM01007
Domain	FHA	CHFR NBN AFDN	8.81e-05	28	58	3	SM00240
Domain	FHA_DOMAIN	CHFR NBN AFDN	1.20e-04	31	58	3	PS50006
Domain	FHA	CHFR NBN AFDN	1.20e-04	31	58	3	PF00498
Domain	SH3_1	EPS8 DST NEBL NEB DNMBP	1.55e-04	164	58	5	PF00018
Domain	RAS	RAP2A RAP2B RAP2C	1.73e-04	35	58	3	PS51421
Domain	FHA_dom	CHFR NBN AFDN	1.89e-04	36	58	3	IPR000253
Domain	-	CHFR NBN AFDN	1.89e-04	36	58	3	2.60.200.20
Domain	Small_GTPase_Ras	RAP2A RAP2B RAP2C	2.05e-04	37	58	3	IPR020849
Domain	SH3	EPS8 DST NEBL NEB DNMBP	5.50e-04	216	58	5	PS50002
Domain	SMAD_FHA_domain	CHFR NBN AFDN	5.64e-04	52	58	3	IPR008984
Domain	SH3_domain	EPS8 DST NEBL NEB DNMBP	5.98e-04	220	58	5	IPR001452
Domain	CNH	CDC42BPG NRK	8.42e-04	14	58	2	SM00036
Domain	CNH	CDC42BPG NRK	9.70e-04	15	58	2	PF00780
Domain	CNH	CDC42BPG NRK	9.70e-04	15	58	2	PS50219
Domain	CNH_dom	CDC42BPG NRK	9.70e-04	15	58	2	IPR001180
Domain	CH	EHBP1 DST DMD	1.08e-03	65	58	3	SM00033
Domain	CH	EHBP1 DST DMD	1.34e-03	70	58	3	PF00307
Domain	-	EHBP1 DST DMD	1.40e-03	71	58	3	1.10.418.10
Domain	HATPase_c	PMS1 MORC4	1.40e-03	18	58	2	SM00387
Domain	Prefoldin	RACGAP1 CFAP57 MORC4	1.46e-03	72	58	3	IPR009053
Domain	CH	EHBP1 DST DMD	1.52e-03	73	58	3	PS50021
Domain	HATPase_c	PMS1 MORC4	1.57e-03	19	58	2	PF02518
Domain	CH-domain	EHBP1 DST DMD	1.64e-03	75	58	3	IPR001715
Domain	-	PMS1 MORC4	1.74e-03	20	58	2	3.30.565.10
Domain	SH3_9	NEBL NEB DNMBP	1.83e-03	78	58	3	PF14604
Domain	HATPase_C	PMS1 MORC4	1.92e-03	21	58	2	IPR003594
Domain	Actinin_actin-bd_CS	DST DMD	2.30e-03	23	58	2	IPR001589
Domain	Spectrin	DST DMD	2.30e-03	23	58	2	PF00435
Domain	ACTININ_2	DST DMD	2.30e-03	23	58	2	PS00020
Domain	ACTININ_1	DST DMD	2.30e-03	23	58	2	PS00019
Domain	Spectrin_repeat	DST DMD	3.65e-03	29	58	2	IPR002017
Domain	Spectrin/alpha-actinin	DST DMD	4.43e-03	32	58	2	IPR018159
Domain	SPEC	DST DMD	4.43e-03	32	58	2	SM00150
Domain	SH3	EPS8 NEBL NEB DNMBP	4.53e-03	216	58	4	SM00326
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	VANGL2 PMS1 EXOC5 TMEM186 RPAP3 CCDC47 ZC3H13 UBR4 APAF1 GATB NBN DDX24 SNRNP200 AQR ADD1 ADD2 ITPR1	4.38e-10	1487	61	17	33957083
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	VANGL2 EHBP1 STK10 EPS8 DST KIAA1217 DMD PLEKHA7 ADD1 ADD2	3.16e-09	421	61	10	36976175
Pubmed	Rap2, but not Rap1 GTPase is expressed in human red blood cells and is involved in vesiculation.	RAP2A RAP2B RAP2C	2.05e-08	4	61	3	16540189
Pubmed	Ubiquitylation by Rab40b/Cul5 regulates Rap2 localization and activity during cell migration.	RAP2A RAP2B RAP2C	5.12e-08	5	61	3	35293963
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	VANGL2 EHBP1 RPL24 DST RPAP3 CCDC47 AFDN SNRNP200 ADD1 ADD2	4.06e-07	708	61	10	39231216
Pubmed	JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function.	RAP2B AFDN RAP2C	6.11e-07	10	61	3	23885123
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PMS1 CDC42BPG DST RNF31 RPAP3 RACGAP1 AFDN AQR ITPR1	1.92e-06	650	61	9	38777146
Pubmed	Rap2A links intestinal cell polarity to brush border formation.	RAP2A RAP2B RAP2C	2.30e-06	15	61	3	22797597
Pubmed	Association between hypertension and variation in the alpha- and beta-adducin genes in a white population.	ADD1 ADD2	3.03e-06	2	61	2	12427140
Pubmed	Prenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylated.	RAP2A RAP2B	3.03e-06	2	61	2	8424780
Pubmed	Primary structure and domain organization of human alpha and beta adducin.	ADD1 ADD2	3.03e-06	2	61	2	1840603
Pubmed	Mild spherocytic hereditary elliptocytosis and altered levels of alpha- and gamma-adducins in beta-adducin-deficient mice.	ADD1 ADD2	3.03e-06	2	61	2	10845937
Pubmed	Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-β signalling.	MAS1 DMD	3.03e-06	2	61	2	24163134
Pubmed	Voltage-gated sodium channel (SkM1) content in dystrophin-deficient muscle.	SCN4A DMD	3.03e-06	2	61	2	11316257
Pubmed	Age-dependent changes in diastolic Ca(2+) and Na(+) concentrations in dystrophic cardiomyopathy: Role of Ca(2+) entry and IP3.	DMD ITPR1	3.03e-06	2	61	2	25242522
Pubmed	Cannabinoid and planar cell polarity signaling converges to direct placentation.	VANGL2 CNR1	3.03e-06	2	61	2	34521753
Pubmed	Identification and biochemical characterization of Rap2C, a new member of the Rap family of small GTP-binding proteins.	RAP2B RAP2C	3.03e-06	2	61	2	16213650
Pubmed	Intra-erythrocyte cation concentrations in relation to the C1797T beta-adducin polymorphism in a general population.	ADD1 ADD2	3.03e-06	2	61	2	17301826
Pubmed	alpha- and beta-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy.	ADD1 ADD2	3.03e-06	2	61	2	19838659
Pubmed	Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions.	NEBL NEB	3.03e-06	2	61	2	19851499
Pubmed	Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy.	DMD CNR1	3.03e-06	2	61	2	30262909
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RPL24 NCOR2 DST RNF31 RPAP3 CCDC47 UBR4 RACGAP1 AFDN DDX24 SNRNP200 AQR	3.41e-06	1353	61	12	29467282
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	PMS1 EHBP1 RPL24 DST NEBL RPAP3 KIAA1217 NBN SNRNP200 ADD1	4.85e-06	934	61	10	33916271
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	EXOC5 RACGAP1 NBN AFDN DDX24 SNRNP200 AQR ADD1	5.98e-06	560	61	8	35241646
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	EHBP1 RPL24 DST NEBL KIAA1217 AFDN PLEKHA7 ADD1	6.38e-06	565	61	8	25468996
Pubmed	Rap2 function requires palmitoylation and recycling endosome localization.	RAP2A RAP2B RAP2C	6.68e-06	21	61	3	19061864
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	STK10 NCOR2 ZC3H13 NBN AFDN DNMBP DDX24 SNRNP200 ADD1	7.88e-06	774	61	9	15302935
Pubmed	Epistatic interaction between alpha- and gamma-adducin influences peripheral and central pulse pressures in white Europeans.	ADD1 ADD2	9.07e-06	3	61	2	15834281
Pubmed	Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice.	ADD1 ADD2	9.07e-06	3	61	2	10485892
Pubmed	Assignment of the human beta-adducin gene (ADD2) to 2p13-p14 by in situ hybridization.	ADD1 ADD2	9.07e-06	3	61	2	7490111
Pubmed	Role of the adducin family genes in human essential hypertension.	ADD1 ADD2	9.07e-06	3	61	2	15716695
Pubmed	Chloride channelopathy in myotonic dystrophy resulting from loss of posttranscriptional regulation for CLCN1.	SCN4A DMD	9.07e-06	3	61	2	17135300
Pubmed	Gly460Trp alpha-adducin mutation as a possible mechanism leading to endolymphatic hydrops in Ménière's syndrome.	ADD1 ADD2	9.07e-06	3	61	2	18667944
Pubmed	Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region.	RAP2A RAP2B	9.07e-06	3	61	2	3045729
Pubmed	Immunofluorescence localization of an adducin-like protein in the chromosomes of mouse oocytes.	ADD1 ADD2	9.07e-06	3	61	2	1864459
Pubmed	Arterial properties in relation to genetic variations in the adducin subunits in a white population.	ADD1 ADD2	9.07e-06	3	61	2	18787518
Pubmed	Erythrocyte adducin: a calmodulin-regulated actin-bundling protein that stimulates spectrin-actin binding.	ADD1 ADD2	9.07e-06	3	61	2	3693401
Pubmed	Sez6l2 regulates phosphorylation of ADD and neuritogenesis.	ADD1 ADD2	9.07e-06	3	61	2	29032200
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PMS1 NCOR2 RPAP3 CCDC47 NBN DMD PTPN18 PLEKHA7 ADD2 ITPR1	1.33e-05	1049	61	10	27880917
Pubmed	Identification and characterization of potential effector molecules of the Ras-related GTPase Rap2.	RAP2A RAP2B	1.81e-05	4	61	2	10085114
Pubmed	A new function for adducin. Calcium/calmodulin-regulated capping of the barbed ends of actin filaments.	ADD1 ADD2	1.81e-05	4	61	2	8626479
Pubmed	Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling.	NEBL NEB	1.81e-05	4	61	2	23985323
Pubmed	Differential roles of Ras and Rap1 in growth factor-dependent activation of phospholipase C epsilon.	RAP2A RAP2B	1.81e-05	4	61	2	12444546
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST DMD	1.81e-05	4	61	2	8954775
Pubmed	beta-adducin (Add2) KO mice show synaptic plasticity, motor coordination and behavioral deficits accompanied by changes in the expression and phosphorylation levels of the alpha- and gamma-adducin subunits.	ADD1 ADD2	1.81e-05	4	61	2	19900187
Pubmed	Adducin: a physical model with implications for function in assembly of spectrin-actin complexes.	ADD1 ADD2	1.81e-05	4	61	2	7642559
Pubmed	Polymorphisms in four candidate genes in young patients with essential hypertension.	ADD1 ADD2	1.81e-05	4	61	2	16497648
Pubmed	Adducin regulation. Definition of the calmodulin-binding domain and sites of phosphorylation by protein kinases A and C.	ADD1 ADD2	1.81e-05	4	61	2	8810272
Pubmed	The WD repeat: a common architecture for diverse functions.	APAF1 CFAP57	1.81e-05	4	61	2	10322433
Pubmed	Analysis of the mobilities of band 3 populations associated with ankyrin protein and junctional complexes in intact murine erythrocytes.	ADD1 ADD2	1.81e-05	4	61	2	22147703
Pubmed	Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.	VANGL2 EHBP1 RPL24 DST CCDC47	2.20e-05	191	61	5	31177093
Pubmed	Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily.	RAP2A AFDN	3.02e-05	5	61	2	10224125
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RPL24 EPS8 RAP2B DST KIAA1217 AFDN DMD PLEKHA7 SNRNP200 ADD1 ADD2	3.47e-05	1431	61	11	37142655
Pubmed	Binding between the junctional proteins afadin and PLEKHA7 and implication in the formation of adherens junction in epithelial cells.	AFDN PLEKHA7	4.52e-05	6	61	2	23990464
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EPS8 RAP2B DST NEBL CCDC47 NBN AFDN RAP2C DNMBP PLEKHA7 AQR	5.21e-05	1497	61	11	31527615
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	VANGL2 EHBP1 STK10 DST DMD ADD1	5.24e-05	377	61	6	38117590
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DST DMD NEB DDX24 SNRNP200	5.78e-05	234	61	5	36243803
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	VANGL2 EHBP1 STK10 EPS8 NRK PLEKHA7 ADD2	6.14e-05	569	61	7	30639242
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	RPL24 DST RPAP3 ZC3H13 KIAA1217 RACGAP1 DDX24 SNRNP200 AQR ADD1	6.18e-05	1257	61	10	36526897
Pubmed	Adducin is an in vivo substrate for protein kinase C: phosphorylation in the MARCKS-related domain inhibits activity in promoting spectrin-actin complexes and occurs in many cells, including dendritic spines of neurons.	ADD1 ADD2	6.32e-05	7	61	2	9679146
Pubmed	Global/temporal gene expression in diaphragm and hindlimb muscles of dystrophin-deficient (mdx) mice.	DMD NEB	6.32e-05	7	61	2	12176734
Pubmed	A Dock-and-Lock Mechanism Clusters ADAM10 at Cell-Cell Junctions to Promote α-Toxin Cytotoxicity.	AFDN PLEKHA7	6.32e-05	7	61	2	30463011
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	EPS8 RAP2B NEBL SLC22A2 APAF1 NEB PKD1L3 RAP2C PLEKHA7	6.64e-05	1016	61	9	19056867
Pubmed	Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies.	NEBL NEB	8.42e-05	8	61	2	11309420
Pubmed	Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes.	MAS1 SLC22A2	8.42e-05	8	61	2	11562346
Pubmed	Long-range DNase I hypersensitivity mapping reveals the imprinted Igf2r and Air promoters share cis-regulatory elements.	MAS1 SLC22A2	8.42e-05	8	61	2	16204191
Pubmed	Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins.	SCN4A DMD	8.42e-05	8	61	2	9412493
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	EHBP1 NCOR2 DST RPAP3 UBR4 MORC4	9.24e-05	418	61	6	34709266
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	VANGL2 EHBP1 KIAA1217 DNMBP PLEKHA7	1.00e-04	263	61	5	34702444
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	RPL24 CDC42BPG RNF31 KIAA1217 SNRNP200	1.02e-04	264	61	5	32814769
Pubmed	The Src homology and collagen A (ShcA) adaptor protein is required for the spatial organization of the costamere/Z-disk network during heart development.	NEBL DMD	1.08e-04	9	61	2	25488665
Pubmed	Tissue-specific regulation of Igf2r/Airn imprinting during gastrulation.	MAS1 SLC22A2	1.08e-04	9	61	2	25918552
Pubmed	Prostaglandin E2 reduces the release and infectivity of new cell-free virions and cell-to-cell HIV-1 transfer.	RAP2A RAP2B	1.08e-04	9	61	2	24586238
Pubmed	Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors.	DMD GPR179	1.08e-04	9	61	2	30282023
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	EHBP1 DST KIAA1217 RACGAP1 AFDN DNMBP PLEKHA7 AQR	1.26e-04	861	61	8	36931259
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DST ZC3H13 UBR4 AFDN DDX24 SNRNP200 AQR	1.44e-04	653	61	7	22586326
Pubmed	The mouse adducin gene family: alternative splicing and chromosomal localization.	ADD1 ADD2	1.65e-04	11	61	2	10602987
Pubmed	The delta subunit of retinal rod cGMP phosphodiesterase regulates the membrane association of Ras and Rap GTPases.	RAP2A RAP2B	1.65e-04	11	61	2	11786539
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	RPL24 RPAP3 UBR4 SNRNP200 AQR	1.85e-04	300	61	5	28561026
Pubmed	Genome-wide CRISPR-cas9 knockout screening identifies GRB7 as a driver for MEK inhibitor resistance in KRAS mutant colon cancer.	RACGAP1 DDX24 SNRNP200	1.89e-04	63	61	3	34718347
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	UBR4 AFDN DMD SNRNP200 ADD1	1.97e-04	304	61	5	32235678
Pubmed	Recapitulation of two genomewide association studies on blood pressure and essential hypertension in the Korean population.	PMS1 PLEKHA7	1.97e-04	12	61	2	20414254
Pubmed	The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.	RPL24 ZC3H13 SNRNP200 AQR	2.26e-04	169	61	4	23084401
Pubmed	Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development.	VANGL2 APAF1	2.33e-04	13	61	2	27789626
Pubmed	Genetic predisposition to tinnitus in the UK Biobank population.	EHBP1 APAF1	2.33e-04	13	61	2	34518561
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	STK10 ZC3H13 RACGAP1 NBN AFDN DDX24	2.52e-04	503	61	6	16964243
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	PMS1 NCOR2 ZC3H13 RACGAP1 NBN AFDN DDX24 SNRNP200	2.53e-04	954	61	8	36373674
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	VANGL2 EHBP1 DST RPAP3 CCDC47 KIAA1217 UBR4 GATB DDX24 ITPR1	2.56e-04	1496	61	10	32877691
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NCOR2 RAP2B DST KIAA1217 UBR4 RACGAP1 AFDN ADD1	2.70e-04	963	61	8	28671696
Pubmed	Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling.	RNF31 ZC3H11B	2.72e-04	14	61	2	32123171
Pubmed	Genetic analysis of the organic cation transporter genes Orct2/Slc22a2 and Orct3/Slc22a3 reduces the critical region for the t haplotype mutant t(w73) to 200 kb.	MAS1 SLC22A2	2.72e-04	14	61	2	11641723
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	RPL24 DST KIAA1217 TTC21B NEB SNRNP200	2.80e-04	513	61	6	25798074
Pubmed	Tagging genes with cassette-exchange sites.	CDC42BPG NCOR2 UBR4 AFDN AQR	3.08e-04	335	61	5	15741177
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	RPL24 CDC42BPG NCOR2 NEBL WDR87 RACGAP1 DDX24 AQR ADD1	3.08e-04	1247	61	9	27684187
Pubmed	RGS12 polarizes the GPSM2-GNAI complex to organize and elongate stereocilia in sensory hair cells.	EPS8 AFDN	3.13e-04	15	61	2	36260679
Pubmed	Quantitative trait loci analysis reveals candidate genes implicated in regulating functional deficit and CNS vascular permeability in CD8 T cell-initiated blood-brain barrier disruption.	MAS1 AFDN	3.13e-04	15	61	2	24090483
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	PMS1 NCOR2 RAP2A DMD DDX24 SNRNP200 ITPR1	3.46e-04	754	61	7	35906200
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	EHBP1 EPS8 NCOR2 CCDC47 KIAA1217 ITPR1	3.53e-04	536	61	6	15840001
Pubmed	Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers.	NEBL NEB	3.57e-04	16	61	2	25987543
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	EHBP1 EPS8 NCOR2 CCDC47 KIAA1217 ITPR1	3.60e-04	538	61	6	10512203
Interaction	EPHA2 interactions	VANGL2 EHBP1 STK10 EPS8 DST MAS1 KIAA1217 AFDN DMD PLEKHA7 ADD1 ADD2	1.13e-06	719	60	12	int:EPHA2
Interaction	LYN interactions	VANGL2 EHBP1 STK10 DST KIAA1217 RACGAP1 AFDN DMD PLEKHA7 ADD1 ADD2 ITPR1	1.14e-06	720	60	12	int:LYN
Interaction	RAC3 interactions	VANGL2 EHBP1 EPS8 CCDC47 KIAA1217 RACGAP1 RAP2C DNMBP ADD1 ADD2 ITPR1	1.83e-06	619	60	11	int:RAC3
Interaction	RAB40B interactions	RAP2A RAP2B DST RAP2C	2.72e-06	33	60	4	int:RAB40B
Interaction	ARF6 interactions	VANGL2 STK10 EXOC5 CCDC47 RACGAP1 AFDN DMD DDX24 PLEKHA7 ADD1	7.91e-06	584	60	10	int:ARF6
Interaction	CXADR interactions	VANGL2 EHBP1 DST NEBL CCDC47 AFDN ADD1 ADD2	1.31e-05	369	60	8	int:CXADR
Interaction	XIRP1 interactions	NEBL SCN4A NEB	1.98e-05	18	60	3	int:XIRP1
Interaction	C11orf52 interactions	VANGL2 EHBP1 EPS8 DST PLEKHA7 ADD1 ADD2	3.73e-05	311	60	7	int:C11orf52
Interaction	ZFPL1 interactions	VANGL2 EHBP1 DST CCDC47 MAS1 PLEKHA7 ADD1 ADD2	5.21e-05	448	60	8	int:ZFPL1
Interaction	AFDN interactions	VANGL2 RAP2A DST KIAA1217 AFDN DNMBP PLEKHA7	5.75e-05	333	60	7	int:AFDN
Interaction	RAC1 interactions	VANGL2 EHBP1 STK10 CDC42BPG EPS8 DST CCDC47 RACGAP1 RAP2C DNMBP ADD1 ADD2	5.82e-05	1063	60	12	int:RAC1
Interaction	RHBDF2 interactions	VANGL2 EHBP1 RPL24 DST CCDC47	1.43e-04	168	60	5	int:RHBDF2
Interaction	ILDR2 interactions	C21orf140 AFDN DDX24	1.53e-04	35	60	3	int:ILDR2
Interaction	RAP2A interactions	RAP2A RAP2B AFDN RAP2C	1.56e-04	91	60	4	int:RAP2A
Interaction	HNRNPCL2 interactions	PMS1 RNF31 APAF1 RACGAP1 DDX24 AQR	1.62e-04	274	60	6	int:HNRNPCL2
Interaction	RALGDS interactions	RAP2A RAP2B AFDN	1.67e-04	36	60	3	int:RALGDS
Interaction	CHN2 interactions	EPS8 RACGAP1 DMD DNMBP	2.00e-04	97	60	4	int:CHN2
Cytoband	10q24.2	CPN1 DNMBP	3.94e-04	22	61	2	10q24.2
Cytoband	17q23.3	CCDC47 SCN4A	7.38e-04	30	61	2	17q23.3
Cytoband	Xq22.3	NRK MORC4	8.93e-04	33	61	2	Xq22.3
Cytoband	12q24.33	CHFR ZNF891	1.88e-03	48	61	2	12q24.33
GeneFamily	RAS type GTPase family	RAP2A RAP2B RAP2C	5.76e-05	31	44	3	389
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	PMS1 EHBP1 STK10 EPS8 NCOR2 DST NBN DMD DNMBP AQR ITPR1	3.36e-06	856	60	11	M4500
Coexpression	HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN	EPS8 RAP2A DST RACGAP1 DMD	3.73e-06	102	60	5	M2124
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	PCSK2 EPS8 NEBL TMC5 PLEKHA7	5.35e-06	184	61	5	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8 SCG2 TMC5 PLEKHA7 CNR1	5.50e-06	185	61	5	4c42bd3cd72f91f4d4ebb849069a03761a2cd662
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK2 DST SCG2 CPN1 ITPR1	5.94e-06	188	61	5	e99e3765b48392c987cf0c5ccbded0655637d7b7
ToppCell	facs-Pancreas-Endocrine-3m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK2 DST SCG2 CPN1 ITPR1	6.42e-06	191	61	5	b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK2 DST SCG2 CPN1 ITPR1	6.42e-06	191	61	5	657297cd19d05a7e7bb74fc3a086fbd95f47aae4
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK2 DST SCG2 UBR4 NEB	6.75e-06	193	61	5	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK2 DST SCG2 UBR4 NEB	6.75e-06	193	61	5	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK2 DST SCG2 UBR4 NEB	6.92e-06	194	61	5	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK2 DST SCG2 UBR4 NEB	6.92e-06	194	61	5	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EPS8 NEBL KIAA1217 TMC5 PLEKHA7	7.83e-06	199	61	5	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	EPS8 RAP2B DST ZC3H13 PTPN18	7.83e-06	199	61	5	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-TSPAN12-L1-2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EPS8 SCG2 TMC5 PLEKHA7 CNR1	8.02e-06	200	61	5	523d799eb315b33b77e02d5b7db63dad8450c4e1
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-TSPAN12\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EPS8 SCG2 TMC5 PLEKHA7 CNR1	8.02e-06	200	61	5	e5cef95e563a6e793ade190ce88c999bfa0af460
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE-P1\|Thalamus / BrainAtlas - Mouse McCarroll V32	RPL24 RAP2A ZNF488 ADD1	4.94e-05	147	61	4	a21b63d0d3aec9ffadf3fac833a0a24da58a95bf
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VANGL2 CDC42BPG WDR87 KIAA1217	6.38e-05	157	61	4	6ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTC21B GATB DMD ITPR1	6.38e-05	157	61	4	f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EHBP1 PCSK2 DST KIAA1217	8.29e-05	168	61	4	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	droplet-Fat-Scat-21m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VANGL2 NEBL AFDN NEB	9.29e-05	173	61	4	f13124b4cf2ac1dc2895f90f5487d6ac681b0ba4
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	STK10 DST SNRNP200 ZNF891	9.50e-05	174	61	4	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPS8 KIAA1217 TMC5 GPR179	9.92e-05	176	61	4	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PMS1 OAF NRK RACGAP1	1.01e-04	177	61	4	3e149bff1f1b393a7abe98984e37981c8296f95d
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK2 SCG2 ZNF488 DMD	1.01e-04	177	61	4	d1dd778d1a52305b1ea3954f81fd5364b3d57bbe
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PMS1 PCSK2 SCG2 CNR1	1.08e-04	180	61	4	f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8 SCG2 PLEKHA7 CNR1	1.11e-04	181	61	4	2f3d04d22d4ac016e61709ea5af3d48885c946c4
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8 SCG2 PLEKHA7 CNR1	1.15e-04	183	61	4	5e361be3ae3fe05098968e58427630127bd12675
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRK ZNF488 DMD NEB	1.18e-04	184	61	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK2 SCG2 DMD CNR1	1.18e-04	184	61	4	ca35a3d2b536c8b2bf5c4d635605e5a3ae94a428
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRK ZNF488 DMD NEB	1.18e-04	184	61	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRK ZNF488 DMD NEB	1.18e-04	184	61	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	DST NEBL AFDN DMD	1.18e-04	184	61	4	561592edc3083fad41b91811151b442207c65dd9
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK2 EPS8 SCG2 CNR1	1.20e-04	185	61	4	16e9ccea0e3b95d90dc48ef74206c805681dac0b
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DST NEBL AFDN TMC5	1.20e-04	185	61	4	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	DST NEBL DMD TMC5	1.20e-04	185	61	4	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	EPS8 KIAA1217 TMC5 PLEKHA7	1.20e-04	185	61	4	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPS8 KIAA1217 DMD TMC5	1.23e-04	186	61	4	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_EGR3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK2 SCG2 DMD CNR1	1.23e-04	186	61	4	77b09af860183606a1775eba921e2071e4a7dd4e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PMS1 PCSK2 SCG2 CNR1	1.25e-04	187	61	4	7b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8 SCG2 PLEKHA7 CNR1	1.25e-04	187	61	4	02105c82a9ba79d2f19e002188377fc3440770c2
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	NEBL KIAA1217 TMC5 PLEKHA7	1.28e-04	188	61	4	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	EPS8 NEBL TMC5 PLEKHA7	1.28e-04	188	61	4	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PCSK2 KIAA1217 TMC5 ITPR1	1.28e-04	188	61	4	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	EPS8 KIAA1217 TMC5 PLEKHA7	1.31e-04	189	61	4	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D231\|Adult / Lineage, Cell type, age group and donor	DST NEBL AFDN TMC5	1.31e-04	189	61	4	5a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell	critical-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DST SCG2 RACGAP1 ZNF488	1.33e-04	190	61	4	05a2c3549b68f49081723bf35db14974274419d5
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	PCSK2 EPS8 TMC5 PLEKHA7	1.36e-04	191	61	4	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	NEBL KIAA1217 AFDN TMC5	1.36e-04	191	61	4	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	droplet-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK2 DST SCG2 UBR4	1.39e-04	192	61	4	0dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	NEBL KIAA1217 TMC5 PLEKHA7	1.39e-04	192	61	4	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NEBL NRK SLC22A2 NEB	1.39e-04	192	61	4	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPL24 EPS8 OAF NRK	1.41e-04	193	61	4	68089ba4123e2f9bea9aae0023a844b5a57bfc0e
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEBL GPR179 ADD2 ITPR1	1.41e-04	193	61	4	7fcfb0f76789fa8d8caa18304cb43c8fd899a81b
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DST SCG2 DMD CNR1	1.44e-04	194	61	4	08fad7591c20568de797cf8e206de2d0b1d78aab
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EPS8 NEBL AFDN TMC5	1.47e-04	195	61	4	9406866f99555198a9be311fbd65751b70f35446
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8 DST AFDN DMD	1.50e-04	196	61	4	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NCOR2 DST SCG2 CNR1	1.50e-04	196	61	4	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	AT2_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	PCSK2 EPS8 NRK TMC5	1.53e-04	197	61	4	5e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NRK SLC22A2 NEB RAP2C	1.53e-04	197	61	4	4ea3f57cd88b8a6bb7cb4b9e3545c0fa8f331886
ToppCell	facs-Lung-EPCAM-24m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK2 C12orf71 SCG2	1.55e-04	76	61	3	98271aadf026a01bf933f8279d11a0413e47d549
ToppCell	proximal-Epithelial-Neuroendocrine\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PCSK2 SCG2 CPN1 NEB	1.56e-04	198	61	4	5dea6078488d584513c0bdbf5bba54877310b54a
ToppCell	proximal-Epithelial-Neuroendocrine-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PCSK2 SCG2 CPN1 NEB	1.56e-04	198	61	4	00ccf3020667cf2130bc354b441b65c0b1b0e862
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PCSK2 EPS8 NEBL TMC5	1.56e-04	198	61	4	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	proximal-3-Epithelial-Neuroendocrine\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PCSK2 SCG2 CPN1 NEB	1.56e-04	198	61	4	a6bc043faf68468d46bac441cf7447c236c7bae4
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	EPS8 CCDC47 ZC3H13 PTPN18	1.56e-04	198	61	4	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NEBL KIAA1217 TMC5 PLEKHA7	1.59e-04	199	61	4	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EPS8 NEBL TMC5 PLEKHA7	1.59e-04	199	61	4	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	Biopsy_Other_PF-Epithelial-AT2\|Biopsy_Other_PF / Sample group, Lineage and Cell type	PCSK2 EPS8 TMC5 CNR1	1.59e-04	199	61	4	9a65acfe9bf500db72142469cf17bf0973540001
ToppCell	critical-Epithelial\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	EPS8 NEBL AFDN TMC5	1.59e-04	199	61	4	bbb44e2a52f102a6d891ead6c06d6c07221abd33
ToppCell	(04)_Interm._basal>secr.-(2)_GFP_FOXI1\|(04)_Interm._basal>secr. / shred by cell type by condition	EPS8 RAP2B ZC3H13 PTPN18	1.59e-04	199	61	4	53ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell	NS-critical-LOC-Epithelial\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EPS8 NEBL KIAA1217 TMC5	1.59e-04	199	61	4	d64adb68502be596ce55fb2cb63fe1cfa2c5f8ba
ToppCell	PSB-critical-LOC-Epithelial\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EPS8 NEBL AFDN TMC5	1.59e-04	199	61	4	58dcb0eedafa8629585dc99e53147e2287f49689
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK2 DST SCG2 ADD2	1.59e-04	199	61	4	47466253069d4b1b8f13ce3210f434e60753b38a
ToppCell	NS-critical-d_07-13-Epithelial\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EPS8 NEBL AFDN TMC5	1.59e-04	199	61	4	b88a81cd2a89f4d27100c96ae4324dcee68daf83
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PCSK2 NEBL TMC5 CNR1	1.59e-04	199	61	4	a38a981cffa61c8444a980916de7414e689a1b63
ToppCell	NS-critical-d_16-33-Epithelial\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EPS8 NEBL AFDN TMC5	1.59e-04	199	61	4	3b68197ec01c5f2b315d9e9b6eb02d5f6b5b77a3
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	STK10 UBR4 SCN4A DNMBP	1.59e-04	199	61	4	667b8b47a5b388506e3177b46747267fad8024f6
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	EPS8 RAP2B ZC3H13 PTPN18	1.59e-04	199	61	4	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	facs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK2 C12orf71 SCG2	1.61e-04	77	61	3	557f7518e9a89d99f3f2474720deb9cde10e1054
ToppCell	control-Epithelial\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NEBL KIAA1217 AFDN TMC5	1.62e-04	200	61	4	f95bbb94e51ac28b1995026c599ec3a34e012916
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DST NEBL KIAA1217 AFDN	1.62e-04	200	61	4	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NEBL KIAA1217 AFDN TMC5	1.62e-04	200	61	4	64462a18afca3c1a8548a857924b8166058bf958
ToppCell	NS-control-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NEBL KIAA1217 AFDN TMC5	1.62e-04	200	61	4	d014959891893b6d3854a471fba1dc50c6625a0a
ToppCell	Bronchus_Control_(B.)-Epithelial-TX\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	EPS8 NEBL KIAA1217 TMC5	1.62e-04	200	61	4	f5bc7d30aa03dd0f95eb64255bd1a2543be8d327
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DST NEBL KIAA1217 AFDN	1.62e-04	200	61	4	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK2 DST SCG2 ADD2	1.62e-04	200	61	4	553e9612874480f4d2a45671462e266cd0a09321
ToppCell	facs-Lung-EPCAM-24m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK2 C12orf71 SCG2	1.81e-04	80	61	3	6720438bf51831e98402a700dfc25bd57e0c6798
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE-P1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	RAP2A ZNF488 ADD1	3.29e-04	98	61	3	fca0baf13520c53edb6da2fe3eb152fbd44df5ed
Drug	GTP[S]	STK10 CDC42BPG RAP2A SCG2 NRK SCN4A AFDN PKD1L3 CNR1 ITPR1	2.19e-06	591	58	10	CID000001764
Drug	Tridihexethyl chloride; Up 200; 11.4uM; PC3; HT_HG-U133A	RAP2B NEBL SCN4A APAF1 AFDN SNRNP200	1.11e-05	198	58	6	5067_UP
Drug	Naltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; MCF7; HT_HG-U133A	EXOC5 NEBL GATB MORC4 NEB DNMBP	1.11e-05	198	58	6	6241_DN
Drug	THC-DMH	DST CNR1	1.91e-05	3	58	2	CID003032800
Disease	hypertension (implicated_via_orthology)	MAS1 PLEKHA7 CNR1 ADD1 ADD2	6.41e-06	128	60	5	DOID:10763 (implicated_via_orthology)
Disease	spastic quadriplegic cerebral palsy 3 (implicated_via_orthology)	ADD1 ADD2	1.22e-05	3	60	2	DOID:0081361 (implicated_via_orthology)
Disease	calpastatin measurement	CPN1 DNMBP	1.13e-04	8	60	2	EFO_0008065
Disease	cerebral palsy (implicated_via_orthology)	ADD1 ADD2	1.81e-04	10	60	2	DOID:1969 (implicated_via_orthology)
Disease	adseverin measurement	CPN1 DNMBP	1.81e-04	10	60	2	EFO_0801358
Disease	3-hydroxyanthranilate 3,4-dioxygenase measurement	CPN1 DNMBP	2.21e-04	11	60	2	EFO_0021862
Disease	Congenital myopathy (disorder)	SCN4A NEB	2.65e-04	12	60	2	C0270960
Disease	Rhabdomyosarcoma	NBN CNR1	4.20e-04	15	60	2	C0035412
Disease	neutrophil collagenase measurement	CPN1 DNMBP	4.79e-04	16	60	2	EFO_0008248
Disease	sphingosine 1-phosphate measurement	DMD ITPR1	6.09e-04	18	60	2	EFO_0800185
Disease	response to heparin, antibody measurement	VANGL2 RPAP3	7.55e-04	20	60	2	EFO_0004556, EFO_0006816
Disease	osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty	NCOR2 ZC3H11B	8.33e-04	21	60	2	EFO_0004616, EFO_0010726, EFO_1000786
Disease	apolipoprotein L1 measurement	CPN1 PKD1L3	1.18e-03	25	60	2	EFO_0021854
Disease	fibrinogen measurement	PCSK2 PKD1L3 ITPR1	1.44e-03	109	60	3	EFO_0004623
Disease	muscular atrophy (biomarker_via_orthology)	APAF1 DMD	1.59e-03	29	60	2	DOID:767 (biomarker_via_orthology)
Disease	IgA glomerulonephritis (is_implicated_in)	ADD1 ADD2	1.71e-03	30	60	2	DOID:2986 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
KMRKQRPAAVQTEEQ	PTPN18	266	Q99952
KRLQEEEQKNPREVM	VANGL2	371	Q9ULK5
QARVLKRVQMEQPDA	TTC21B	861	Q7Z4L5
SNPEVVMKRRRQQKL	AFDN	216	P55196
EKVRNEPTQQQRAAM	APAF1	41	O14727
IVVKERRQQEEQRPK	C21orf140	121	B9A014
NPEQRMLEKRAKVIE	DNMBP	776	Q6XZF7
VMDVKNRNPRAINKL	GATB	516	O75879
ETFNIIMRRKPKENN	AQR	651	O60306
IKQKATMQDLEQRRP	DMD	2511	P11532
QDIKPMRDQIIRVKR	RAP2A	91	P10114
QDIKPMRDQIIRVKR	RAP2B	91	P61225
QDIKPMRDQIVRVKR	RAP2C	91	Q9Y3L5
EEQQKQQRREMLKDP	CDC42BPG	1416	Q6DT37
QFPEIRKQRELQERM	NCOR2	336	Q9Y618
RAFKDEMQPRRQKDN	MAS1	301	P04201
MRKKPERLVREQEAV	GPR179	1306	Q6PRD1
KPNRERQKLMREQNI	ITPR1	501	Q14643
VDSQQKSPVKRRRMQ	DST	1376	Q03001
QIEPRENEIRVMKEQ	CFAP57	986	Q96MR6
KERIMNEEDPEKQRR	CCDC47	441	Q96A33
NTPRQRAVEAQKLMK	EXOC5	121	O00471
ARNKITQDMLQPKVR	CHFR	381	Q96EP1
PQARKKEMEMRQLQR	CPN1	441	P15169
QVPKEKVERNRTAMD	GSTT2	126	P0CG29
KVQVTRPDQARMDIR	CNR1	326	P21554
NRPEMKRQRSIQEDT	EHBP1	1026	Q8NDI1
GKADQQEERRRQKQM	DDX24	771	Q9GZR7
KQLPVDRRKSQMEEV	EPS8	676	Q12929
IEEAENMQRPRKNKE	SLC22A2	526	O15244
IEKRRSQNIKMVQIP	PMS1	686	P54277
NNDPESKRRQEEMLK	NRK	1286	Q7Z2Y5
EARLQRNKQMEIEEP	SCN4A	36	P35499
RNKQMEIEEPERKPR	SCN4A	41	P35499
QKQEEDVNVRKRPRM	NBN	581	O60934
DVNVRKRPRMDIETN	NBN	586	O60934
EPVEKRRRLQNEMTT	MORC4	571	Q8TE76
MPRLNKENEQQTKRI	PKD1L3	1221	Q7Z443
RDMEKVERQAVPQAN	PLEKHA7	291	Q6IQ23
PNNQKRERMDEEQKL	SCG2	211	P13521
ETMKRLEDPVQRQRV	KIAA1217	691	Q5T5P2
TMLQDIKRQPKVVER	RACGAP1	516	Q9H0H5
AMAKLRQKNPRAVRQ	OAF	116	Q86UD1
DPQEVLEMRNKIREQ	ADD2	491	P35612
PKEVQEMRNKIREQN	ADD1	496	P35611
IGRRMKRQDQIQDEP	C12orf71	66	A8MTZ7
MVQERKNEKPVRIFN	C10orf120	21	Q5SQS8
PEKQRQDKMREEGLQ	RNF31	476	Q96EP0
PRMKDRQVDAQAQER	ZNF488	106	Q96MN9
MAKRNQKPEVRKAQR	RPL24	91	P83731
QKPEVRKAQREQAIR	RPL24	96	P83731
KQKDMELRRQNGVPE	RPAP3	36	Q9H6T3
NEVEKLPRQQRKESM	STK10	666	O94804
ETKDRPQEMFVRIQR	TMEM186	166	Q96B77
RMQKQQEREKSVLTP	ZC3H11B	566	A0A1B0GTU1
AQRTKPQMQEERRAK	SNRNP200	56	O75643
IKAIRNQPRTMEEKR	TMC5	366	Q6UXY8
NQPRTMEEKRNLRKI	TMC5	371	Q6UXY8
RVALEEMENKPRKQQ	UBR4	4861	Q5T4S7
EVMPREEEQAQKKAR	WDR87	1341	Q6ZQQ6
DQEEIRNMKKRIPQA	ZNF891	96	A8MT65
RERMKNKRQDVDTEP	ZC3H13	86	Q5T200
VTPEMERVKKNQENI	NEBL	731	O76041
VTPEMQRVKRNQENI	NEB	6321	P20929
KQQLERDPRVKMALQ	PCSK2	86	P16519