Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainUSP_CS

USP7 USP1

4.70e-0366292IPR018200
DomainUSP_1

USP7 USP1

5.27e-0370292PS00972
DomainIQ

IQGAP3 MYO1F

5.41e-0371292PF00612
DomainUCH

USP7 USP1

5.41e-0371292PF00443
DomainUSP_2

USP7 USP1

5.41e-0371292PS00973
DomainUSP_3

USP7 USP1

5.56e-0372292PS50235
DomainUSP_dom

USP7 USP1

5.56e-0372292IPR028889
DomainPeptidase_C19_UCH

USP7 USP1

5.56e-0372292IPR001394
DomainIQ

IQGAP3 MYO1F

6.99e-0381292SM00015
DomainTRYPSIN_SER

TPSAB1 TPSB2

8.57e-0390292IPR033116
DomainIQ_motif_EF-hand-BS

IQGAP3 MYO1F

8.57e-0390292IPR000048
DomainIQ

IQGAP3 MYO1F

9.13e-0393292PS50096
DomainTRYPSIN_HIS

TPSAB1 TPSB2

1.11e-02103292IPR018114
DomainTRYPSIN_SER

TPSAB1 TPSB2

1.17e-02106292PS00135
DomainTRYPSIN_HIS

TPSAB1 TPSB2

1.19e-02107292PS00134
DomainPeptidase_S1A

TPSAB1 TPSB2

1.32e-02113292IPR001314
DomainTRYPSIN_DOM

TPSAB1 TPSB2

1.37e-02115292PS50240
DomainTryp_SPc

TPSAB1 TPSB2

1.41e-02117292SM00020
DomainTrypsin

TPSAB1 TPSB2

1.51e-02121292PF00089
DomainTrypsin_dom

TPSAB1 TPSB2

1.51e-02121292IPR001254
Pubmed

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.

TPSAB1 TPSB2

6.71e-0722929521329
Pubmed

The structure of the human betaII-tryptase tetramer: fo(u)r better or worse.

TPSAB1 TPSB2

6.71e-07229210500112
Pubmed

Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family.

TPSAB1 TPSB2

6.71e-0722922187193
Pubmed

Characterization of a tryptase mRNA expressed in the human basophil cell line KU812.

TPSAB1 TPSB2

6.71e-0722928434231
Pubmed

Structural requirements and mechanism for heparin-dependent activation and tetramerization of human betaI- and betaII-tryptase.

TPSAB1 TPSB2

6.71e-07229215567416
Pubmed

Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft.

TPSAB1 TPSB2

6.71e-07229210391906
Pubmed

The human mast cell tryptase tetramer: a fascinating riddle solved by structure.

TPSAB1 TPSB2

6.71e-07229210708850
Pubmed

Cloning and characterization of a second complementary DNA for human tryptase.

TPSAB1 TPSB2

6.71e-0722922203827
Pubmed

Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels.

TPSAB1 TPSB2

6.71e-07229217449330
Pubmed

Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia.

TPSAB1 TPSB2

6.71e-07229231337736
Pubmed

Characterization of two highly polymorphic human tryptase loci and comparison with a newly discovered monkey tryptase ortholog.

TPSAB1 TPSB2

6.71e-07229210898108
Pubmed

Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3.

TPSAB1 TPSB2

2.01e-0632929920877
Pubmed

Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations.

TPSAB1 TPSB2

2.01e-06329219748655
Pubmed

Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia.

USP7 RNF6

4.02e-06429235926709
Pubmed

Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families.

TPSAB1 TPSB2

6.70e-06529210843716
Pubmed

New developments in the genetics and activation of mast cell proteases.

TPSAB1 TPSB2

1.00e-05629212217407
Pubmed

Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA.

USP7 USP1

1.00e-05629232510829
Pubmed

The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.

USP7 USP1

2.41e-05929222195557
Pubmed

Deubiquitinating enzymes: a new class of biological regulators.

USP7 USP1

7.00e-05152929827704
Pubmed

A genome wide association study identifies common variants associated with lipid levels in the Chinese population.

USP1 RYR2

9.06e-051729224386095
Pubmed

P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma.

USP7 NAT10

1.99e-042529236708875
Pubmed

Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.

WASHC5 RASSF2

5.39e-04412928724849
Cytoband16p13.3

USP7 TPSAB1 TPSB2

4.89e-0424429316p13.3
CytobandEnsembl 112 genes in cytogenetic band chr16p13

USP7 TPSAB1 TPSB2

2.42e-03426293chr16p13
GeneFamilyUbiquitin specific peptidases

USP7 USP1

1.24e-0356172366
CoexpressionAtlasgallbladder

B3GALT2 TPSAB1 TCN1 TPSB2

4.70e-05148294gallbladder
CoexpressionAtlasgeo_heart_top-relative-expression-ranked_500_k-means-cluster#5

TPSAB1 TPSB2

5.02e-058292geo_heart_500_K5
ToppCellTracheal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 RASSF2 PTGS1 TPSB2 MYO1F

1.80e-07200295ad7ae5106141669b353800fece833b3cd5bdccee
ToppCellFetal_29-31_weeks-Immune-mast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TPSAB1 TCN1 PTGS1 TPSB2

1.69e-061342941d6e74612fd91a2ef9d14bf77262b2d08e1052ca
ToppCellAdult-Immune-mast_cell-D231|Adult / Lineage, Cell type, age group and donor

TPSAB1 PTGS1 IQGAP3 TPSB2

3.17e-061572944c63bb91f8708644e6ce2500072a4eeb8e1079dd
ToppCellAdult-Immune-mast_cell|Adult / Lineage, Cell type, age group and donor

TPSAB1 PTGS1 IQGAP3 TPSB2

3.50e-0616129444f5c0256b3ce264a6c7b62740f32dcd45ee052d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mast-Mast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TPSAB1 TCN1 PTGS1 TPSB2

3.59e-0616229430508c4007faa38b76246e3c6d7b3fde4492cc85
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TPSAB1 TCN1 PTGS1 TPSB2

3.59e-0616229433b73c6727b5c5ada2dddf304f56d84397725ca8
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mast-Mast-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TPSAB1 TCN1 PTGS1 TPSB2

3.59e-0616229444ef0932ee38964ff11edc2aa14698d9db3b2b6b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 RASSF2 TPSB2 MYO1F

3.76e-061642942c929996a19bbe29949010928001c277b5494a42
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 RASSF2 TPSB2 MYO1F

4.24e-061692942e15a9317da4017757d184f7cc91bd66b072ac51
ToppCellBronchial_Biopsy-Immune-Mast_cells|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

TPSAB1 RASSF2 PTGS1 TPSB2

4.55e-06172294c477008444d2d71071177807870d7455e90c2fad
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 PTGS1 TPSB2 MYO1F

4.55e-061722943a37569a5902f3c65ff8d3912421309a8c82ee9b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 PTGS1 TPSB2 MYO1F

4.55e-06172294cc9d9dae290f11f8c348c78228af4e49469dc93b
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPSAB1 TCN1 PTGS1 TPSB2

4.55e-061722942ab720a4c96073339a1f8b95ec7699682df98acf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 RASSF2 TPSB2 MYO1F

4.65e-061732949eaec30f9a3655b53ece1b66848201a7f85bbdf5
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPSAB1 TCN1 PTGS1 TPSB2

4.76e-0617429436080fa12497faa752ff07ae52cd3864053eafef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 RASSF2 PTGS1 TPSB2

5.09e-0617729486c41d262142eeaa95ea7fa6668169eb1bb2953f
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 RASSF2 PTGS1 TPSB2

5.81e-061832948b7f9e55c21c99395c71c5ac4f5db0f6c5733ef9
ToppCell3'_v3-lymph-node_spleen-Mast|lymph-node_spleen / Manually curated celltypes from each tissue

TPSAB1 TCN1 PTGS1 TPSB2

5.94e-0618429483675c7a083c52fb74dc8b9d35df0ef69715f707
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 RASSF2 TPSB2 MYO1F

6.60e-061892947ccea2df93bb4b37417bbc8f6c85a61ece95211a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 RASSF2 TPSB2 MYO1F

6.88e-06191294468b5149d1533f03521844d3cce8633d44eb6ed4
ToppCellproximal-3-Hematologic-Basophil/Mast_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TPSAB1 RASSF2 PTGS1 TPSB2

7.32e-06194294e4160e79dea68ac8183b67e840b7b6d08e03d156
ToppCellproximal-Hematologic-Basophil/Mast_2-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TPSAB1 RASSF2 PTGS1 TPSB2

7.32e-0619429435667c3a077f505abd14eb7e9c75c4a12dc30ca0
ToppCellproximal-Hematologic-Basophil/Mast_2|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TPSAB1 RASSF2 PTGS1 TPSB2

7.32e-06194294b017dbb9b18d617a6da4994b05436d193dc2aef5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 RASSF2 TPSB2 MYO1F

7.47e-06195294391d8e00dd5f988baa6dbda8414d3c020679ea2f
ToppCellTracheal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 RASSF2 PTGS1 TPSB2

7.93e-06198294cc5ca64749e2f4f1d373d9472824df85741702b7
ToppCellTracheal-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 RASSF2 PTGS1 TPSB2

7.93e-06198294d4d66f19df078bfc3a83d4664aaf9c7789bde1a5
ToppCellParenchymal-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 RASSF2 PTGS1 TPSB2

8.25e-062002949156f8fd61a833891d2f7b7fadd693b81b1e2d5a
ToppCellCaecum|World / Region, Cell class and subclass

B3GALT2 TPSAB1 MSC TPSB2

8.25e-06200294f8e3285f5ea7fef1b7b7089bd8b0f1ddb0625dfb
ToppCellParenchymal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 RASSF2 PTGS1 TPSB2

8.25e-06200294566fe2e78e6f35399ec6aad5964f6d4d8ade82c6
ToppCellCaecum|World / shred on region, Cell_type, and subtype

B3GALT2 TPSAB1 MSC TPSB2

8.25e-06200294b46601ca1e949c825309484308c8f53e484b65cd
ToppCelllymphoid-T_cell-pro-T_cell|lymphoid / Lineage, cell class and subclass

TPSAB1 TCN1 IQGAP3

3.51e-05982934da11182885d5f2673e85bd9c5717939b0268427
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-basophil|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPSAB1 TPSB2 EPB42

7.26e-05125293dec39707624529689f68dd46f910a71db5e91ab2
ToppCellSevere-Myeloid-Mast-|Severe / Condition, Lineage, Cell class and cell subclass

TPSAB1 PTGS1 TPSB2

1.13e-04145293ce307d45425a5191882078f049f85477eec40b69
ToppCellSevere-Myeloid-Mast|Severe / Condition, Lineage, Cell class and cell subclass

TPSAB1 PTGS1 TPSB2

1.13e-04145293e0bfd2ffdbd6c197ef0a04e983396ebd87ef7127
ToppCellChildren_(3_yrs)-Immune-mast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPSAB1 PTGS1 TPSB2

1.15e-04146293f7349d63bb47f1f22ced8ff514edc1c11bc782e7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 RASSF2 TPSB2

1.27e-04151293f5ae450e3daa10540ca8437d05efe2d86ac70960
ToppCell368C-Myeloid-Mast_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 PTGS1 TPSB2

1.30e-04152293faf30245a1690aaa27c7be0832797c340e4af4d7
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Mast_cell-Mast_cell|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 PTGS1 TPSB2

1.30e-04152293321d322d58c12fd752de4e8ea873f3f367302813
ToppCell368C-Myeloid-Mast_cell-|368C / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 PTGS1 TPSB2

1.30e-04152293519c9ed05fdaf420e42147ffae1dc05a7f86fdd4
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Mast_cell|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 PTGS1 TPSB2

1.30e-04152293a4d50e9af02231c5573aee905cf0905391e6da34
ToppCellAdult-Immune-mast_cell-D122|Adult / Lineage, Cell type, age group and donor

TPSAB1 PTGS1 TPSB2

1.37e-041552937c9de0591d1bf756b8e268b278bbe10bd5415dcd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 PTGS1 TPSB2

1.37e-04155293231fbbbd6e6f9c86be7a15a9ec0804e6b9ab3b5f
ToppCellCOVID-19-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

TPSAB1 PTGS1 TPSB2

1.40e-04156293159504d43421ee83b9ab484816333ae549c9c2fd
ToppCellCOVID-19-Mast_cells-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

TPSAB1 PTGS1 TPSB2

1.40e-04156293bc10b94673184ef384c6665b16a1209a8975a4f1
ToppCellChildren_(3_yrs)-Immune-mast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPSAB1 PTGS1 TPSB2

1.42e-04157293ec185dbeabb67fd9ca85f71cab88463b60f9b1c1
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic-mast_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPSAB1 PTGS1 TPSB2

1.48e-04159293ecd1daa33549541aee3bf4e139ab6732efc8e74c
ToppCell10x5'-bone_marrow-Mast|bone_marrow / Manually curated celltypes from each tissue

TPSAB1 TCN1 TPSB2

1.48e-04159293c3d3570e83c5d25cc92fa3a7a8f0dc2f89a72913
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPSAB1 PTGS1 TPSB2

1.48e-041592937b6370c9567da7d40541c6e243efa704ed7e90ae
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

TPSAB1 PTPRG RYR2

1.48e-041592933f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

WASHC5 IQGAP3 AMOTL1

1.48e-04159293a710551512aa0b7a281a81bea651a43c9f3b3539
ToppCell343B-Myeloid-Mast_cell-|343B / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 PTGS1 TPSB2

1.51e-04160293a2f09b5955602819c8978f4372130c8ef915cd07
ToppCelldroplet-Fat-SCAT-30m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GALT2 TPSAB1 TPSB2

1.51e-0416029367ee7a314d7d4d3ea206e0158083f36f6dd7e80b
ToppCelldroplet-Fat-SCAT-30m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GALT2 TPSAB1 TPSB2

1.51e-04160293fc76337ad766c859db390ef8b6fb9caeaace3a56
ToppCell343B-Myeloid-Mast_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 PTGS1 TPSB2

1.51e-04160293133ecae0a894d9a0d49d58859623359096b6f030
ToppCelldroplet-Fat-SCAT-30m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GALT2 TPSAB1 TPSB2

1.51e-04160293759749f708c3a2b36692d42499f19aff937e592f
ToppCell10x5'-bone_marrow-Mast-Mast_cells|bone_marrow / Manually curated celltypes from each tissue

TPSAB1 TCN1 TPSB2

1.53e-0416129315ba7e69699558353cfeecdcf1dbc2e147379ed6
ToppCellBL-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TPSAB1 TCN1 PTGS1

1.56e-0416229325ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCellFetal_29-31_weeks-Immune-mast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TPSAB1 PTGS1 TPSB2

1.59e-0416329303b2ec226adffba3ce893f3d12e549c841e662fd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 PTGS1 TPSB2

1.62e-041642932c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCN1 PTGS1 IQGAP3

1.62e-041642932a230ea066decb798a0e6f2b96c7608c8e608031
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCN1 PTGS1 IQGAP3

1.62e-04164293d02d39edd0bfef5a53b814ec6d5f026d41253218
ToppCellMild-Myeloid-Mast-|Mild / Condition, Lineage, Cell class and cell subclass

TPSAB1 PTGS1 TPSB2

1.65e-0416529393d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCellnucseq-Immune-Hematopoietic-Granulocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TPSAB1 PTGS1 TPSB2

1.65e-0416529337615622c736e43260c38016e7c9e565ac97a3e8
ToppCellMild-Myeloid-Mast|Mild / Condition, Lineage, Cell class and cell subclass

TPSAB1 PTGS1 TPSB2

1.65e-041652935fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCellnucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TPSAB1 PTGS1 TPSB2

1.65e-04165293640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCellnucseq-Immune-Hematopoietic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TPSAB1 PTGS1 TPSB2

1.65e-04165293f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCell10x3'2.3-week_14-16-Hematopoietic-erythroid-late_erythroid|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TPSAB1 TCN1 EPB42

1.68e-04166293b4e5466a33578103d197cf67f37e7ec88e09281f
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 PTGS1 TPSB2

1.68e-04166293a42268a02a89fc97272e45c4cbe21acf04b7428c
ToppCellwk_20-22-Hematologic-Myeloid-Mast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TPSAB1 PTGS1 TPSB2

1.68e-04166293004ab6a1425d812c7ce572205875fd702d4a9659
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 PTGS1 TPSB2

1.71e-04167293a813b95c2fafb638b249bc4fa4f708c6f39ad444
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 PTGS1 TPSB2

1.71e-041672930aa1973141a2437df24c9857cd50ff3dfc7673c0
ToppCell10x5'-lymph-node_spleen-Mast-Mast_cells|lymph-node_spleen / Manually curated celltypes from each tissue

TPSAB1 PTGS1 TPSB2

1.74e-04168293650ad3ea52577887885d82457dbc04202ce3eb34
ToppCell3'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 PTGS1 TPSB2

1.74e-0416829355f328353119cbdc521c782ebb8d163876f4186d
ToppCell10x5'-lymph-node_spleen-Mast|lymph-node_spleen / Manually curated celltypes from each tissue

TPSAB1 PTGS1 TPSB2

1.74e-04168293e58ffbb57c81967766755c3f6f347b158a39cb0d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RASSF2 PTGS1 MYO1F

1.77e-04169293b2fdf9f842dc7c181bc951a8a6932c916ed835ef
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RASSF2 PTGS1 MYO1F

1.77e-041692932322f03a115c662f808ebfc892192b7d38d48181
ToppCellControl-Mast_cells|Control / group, cell type (main and fine annotations)

TPSAB1 PTGS1 TPSB2

1.77e-04169293fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCellCOVID-19-lung-MAST|lung / Disease (COVID-19 only), tissue and cell type

TPSAB1 PTGS1 TPSB2

1.80e-04170293e90f18e5462381b38e918442b38b1c8105291908
ToppCellControl-Myeloid-Mast|Control / Disease state, Lineage and Cell class

TPSAB1 PTGS1 TPSB2

1.80e-041702939a14deb7f7cd4a49c217eba4023f7bf1dec6c902
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPSAB1 TPSB2 MYO1F

1.80e-04170293c4f00c1acde1d3b521101e469101d10fd257653e
ToppCellControl-Mast_cells-Mast_cells|Control / group, cell type (main and fine annotations)

TPSAB1 PTGS1 TPSB2

1.80e-04170293c80f6d29096c372da95a8407f402349ff1bb7018
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPSAB1 TPSB2 MYO1F

1.80e-04170293d3c1edaf0190d8927578043c372dba7477e75e14
ToppCellwk_20-22-Hematologic-Myeloid-Eosinophil|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TPSAB1 PTGS1 TPSB2

1.83e-04171293fa6e856e62b82ec4972e0098e73f237cc611891f
ToppCellcontrol-Myeloid-Eosinophils|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TPSAB1 TCN1 TPSB2

1.83e-0417129382f736c33ed96c0865618e8f8eb82a5487126bdc
ToppCellControl-Myeloid-Mast|World / Disease state, Lineage and Cell class

TPSAB1 PTGS1 TPSB2

1.83e-04171293ed8e61d524f4cddc6084b261175df54d2a64a60f
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 PTGS1 TPSB2

1.83e-041712935885e69e997cc2f6a27afebfe57001ca0ac062a6
ToppCell3'_v3-GI_small-bowel-Mast-Mast_cell_granulo-myelo|GI_small-bowel / Manually curated celltypes from each tissue

TPSAB1 PTGS1 TPSB2

1.86e-041722933df11aefc09762fd1f94441324551178e030b249
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 PTGS1 TPSB2

1.86e-0417229313d7117f92a92d77d6b4335ed800c585dc8b4511
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 PTGS1 TPSB2

1.86e-041722933d83b2f03ad3af4dae3fe6cc0a0ef356872ca94f
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 PTGS1 TPSB2

1.86e-04172293a3d431aed12c1192e8dca1dc85b8340fb7354f8d
ToppCellImmune-mast_cell|World / Lineage, Cell type, age group and donor

TPSAB1 PTGS1 TPSB2

1.86e-041722936e8e0aac5a20dbc789bf8c6916833bb8709a411a
ToppCellwk_15-18-Hematologic-Myeloid-Mast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TPSAB1 PTGS1 TPSB2

1.86e-04172293a7146c255031207e64682ef767884b11c96e0d59
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 PTGS1 TPSB2

1.86e-04172293028a5441242b2cc760cafc1822120180619c63ae
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 PTGS1 TPSB2

1.86e-041722939fc70b1a143a8ec910336c23b761d908bb6aecb2
ToppCell10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TPSAB1 PTGS1 TPSB2

1.90e-041732931e4afa020fae682521335b440ccd33c16f37156f
ToppCell368C-Myeloid-Mast_cell|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 PTGS1 TPSB2

1.90e-041732938cffb4a37d30b6626188309b868ac4a62e91262f
ToppCellLV-17._Lymphocyte|World / Chamber and Cluster_Paper

TPSAB1 TPSB2 MYO1F

1.90e-04173293212f013ff761cbab24a537071739867c08c402a4
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPSAB1 PTGS1 TPSB2

1.90e-04173293a7dee23b1d43d3070d502487af319ff81a9a747b
ToppCell368C-Myeloid-Mast_cell-|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 PTGS1 TPSB2

1.90e-04173293fb87ea74bf70aa83b458edf728c81857c8b8eb96
ToppCell10x5'-GI_small-bowel-Mast|GI_small-bowel / Manually curated celltypes from each tissue

TPSAB1 PTGS1 TPSB2

1.93e-04174293e94c980b25edfd0e8598c416828801fcc00e8ead
Drugthymidine glycol monophosphate

TPSAB1 TPSB2

4.70e-063292CID000165415
DrugBrunfelsamidine

TPSAB1 TPSB2

9.38e-064292CID005281683
DrugCI-U

TPSAB1 PTGS1 TPSB2

1.18e-0535293CID000004357
DrugS)-bromoenol lactone

GPLD1 TPSAB1 PTGS1 TPSB2

1.52e-05119294CID000002445
Drugisocoumarin

TPSAB1 PTGS1 TPSB2

1.65e-0539293CID000068108
DrugAttpsa

TPSAB1 TPSB2

2.34e-056292CID005487511
Drugioxaglate

TPSAB1 TPSB2

3.28e-057292CID000003742
DrugTelebrix

TPSAB1 TPSB2

3.28e-057292CID000034536
Drugdaphnodorin C

TPSAB1 TPSB2

5.61e-059292CID000072428
Drug1c5s

TPSAB1 TPSB2

7.00e-0510292CID000444753
DrugAC1NUP69

TPSAB1 TPSB2

7.00e-0510292CID005487154
Drugsuccinylcholine

TPSAB1 TPSB2 RYR2

7.35e-0564293CID000005314
Drugphytosphingosine

GPLD1 TPSAB1 TPSB2

8.05e-0566293CID000122121
DrugZ-ala-ala-lys-mna

TPSAB1 TPSB2

8.55e-0511292CID005486901
Drugpimaradiene

TPSAB1 TPSB2

8.55e-0511292CID000440909
Drugdaphnodorin A

TPSAB1 TPSB2

8.55e-0511292CID000072426
DrugAC1NSU64

TPSAB1 TPSB2

8.55e-0511292CID005316303
Drugmethylhistamine

TPSAB1 TPSB2

8.55e-0511292CID000000912
DrugCefalonium [5575-21-3]; Down 200; 8.8uM; PC3; HT_HG-U133A

USP7 RNF6 RYR2 MYO1F

1.01e-041932944245_DN
Drugbis(5-amidino-2-benzimidazolyl)methane

TPSAB1 TPSB2

1.03e-0412292CID000002386
DrugNSC-648146

TPSAB1 TPSB2

1.03e-0412292CID000372649
Drug4-amidinophenylpyruvic acid

TPSAB1 TPSB2

1.03e-0412292CID000151496
DrugElocom

TPSAB1 TPSB2

1.03e-0412292CID000123620
DrugTetrahydroxy-1,4-quinone monohydrate [319-89-1]; Down 200; 21uM; MCF7; HT_HG-U133A

PLEKHB2 GPLD1 TCN1 PTGS1

1.03e-041942944159_DN
DrugProtriptyline hydrochloride [1225-55-4]; Down 200; 13.4uM; PC3; HT_HG-U133A

EVC TCN1 ARMH3 NAT10

1.05e-041952946338_DN
Drughomoserine

TPSAB1 MSC TPSB2

1.09e-0473293CID000000779
Drugazelastine

TPSAB1 PTGS1 TPSB2

1.13e-0474293CID000002267
DrugZ-ARR-AFC

TPSAB1 TPSB2

1.21e-0413292CID000125067
DrugNk3201

TPSAB1 TPSB2

1.21e-0413292CID000213050
Drugnafamostat mesilate

TPSAB1 PTGS1 TPSB2

1.28e-0477293CID000004413
DrugABPH

TPSAB1 TPSB2

1.41e-0414292CID000092377
Drug11-trans-leukotriene E4

TPSAB1 PTGS1 TPSB2

1.43e-0480293CID000003909
Drugmethacholine

TPSAB1 TCN1 PTGS1 TPSB2

1.58e-04217294CID000001993
DrugDB07356

TPSAB1 PTGS1 TPSB2

1.59e-0483293CID011840917
DrugAC1L9K4M

TPSAB1 TPSB2

1.63e-0415292CID000446820
DrugFdTTP

TPSAB1 TPSB2

1.63e-0415292CID000162005
Drug5 alpha-androstan-3-one

TPSAB1 TPSB2

1.86e-0416292CID000102028
Drugthymidine glycol

TPSAB1 TPSB2

1.86e-0416292CID003035041
Drug(E)-4-aminohex-4-enoic acid

TPSAB1 TPSB2

1.86e-0416292CID005288385
Drugkazinol B

PTGS1 RYR2

2.11e-0417292CID000480869
Drugmethylimidazoleacetic acid

TPSAB1 TPSB2

2.11e-0417292CID000075810
DrugH 17

TPSAB1 TPSB2

2.11e-0417292CID000476867
DrugProstaglandin D2-d4

GPLD1 TPSAB1 PTGS1 TPSB2

2.32e-04240294CID000004956
Drug2-azetidinone

TPSAB1 TPSB2

2.37e-0418292CID000136721
Drug6-trans-leukotriene B4

GPLD1 TPSAB1 PTGS1 TPSB2

2.59e-04247294CID000000169
DrugNSC49103

TPSAB1 TPSB2

2.93e-0420292CID000005251
DrugA80a

TPSAB1 TPSB2

2.93e-0420292CID005487000
Drugatracurium besylate

TPSAB1 TPSB2

3.56e-0422292CID000047320
Drugthiopental

TPSAB1 TPSB2 RYR2

3.86e-04112293CID003000715
Drugtryptophanyl-5'AMP

TPSAB1 TPSB2

3.90e-0423292CID000446202
DrugKinetensin

TPSAB1 TPSB2

3.90e-0423292CID000147043
DrugPL 0

TPSAB1 TPSB2

4.25e-0424292CID000016157
DrugAC1L8VEV

TPSAB1 TPSB2

4.25e-0424292CID000433433
DiseaseFlushing

TPSAB1 PTGS1

1.30e-056282C0016382
Diseasetryptase beta-2 measurement

TPSAB1 TPSB2

3.11e-059282EFO_0008306
Diseaseurticaria

TPSAB1 TPSB2

1.63e-0420282EFO_0005531
Diseasegeneralised epilepsy

ARMH3 RYR2

1.12e-0352282EFO_0005917
Diseasebasophil measurement

TPSAB1 TPSB2

1.49e-0360282EFO_0803539
DiseaseEsophageal Neoplasms

RNF6 PTGS1

2.49e-0378282C0014859
DiseaseMalignant neoplasm of esophagus

RNF6 PTGS1

2.49e-0378282C0546837
DiseaseAutism Spectrum Disorders

IQGAP3 RYR2

2.95e-0385282C1510586

Protein segments in the cluster

PeptideGeneStartEntry
QYARVGEEYQELQLD

PTPRG

91

P23470
RLLIDEYYNEEGLQN

EPB42

301

P16452
ENRVLHQELQGYYDN

AMOTL1

451

Q8IY63
LQDGLDQYERYSEQH

ARMH3

636

Q5T2E6
NLYYEGQNLQLRHRE

RASSF2

31

P50749
HIYGDNLERQYQLRL

PTGS1

231

P23219
ENLYHNILNIYENIL

MROH9

96

Q5TGP6
VQIGLEDYINDRQYD

HNF4G

266

Q14541
LHYQDLLQLQYEGVA

IQGAP3

1591

Q86VI3
DALQYQEHLDYEIIQ

NAT10

331

Q9H0A0
LEESRQYHDIIQQEY

B3GALT2

206

O43825
LAYEELLQRHQGQYQ

ITIH6

146

Q6UXX5
QAYYQQIGRIMEDHE

EVC

791

P57679
LQQLIRYVDEAHQYI

RYR2

2926

Q92736
LRVQLREQHLYYQDQ

TPSAB1

86

Q15661
LRVQLREQHLYYQDQ

TPSB2

86

P20231
HLIYYDDQTRQNIED

PLEKHB2

31

Q96CS7
QERLHREEAYYQFIN

RNF6

31

Q9Y252
RYLDDLNEGVYIQQT

WASHC5

111

Q12768
RNAEENLIYDYHLID

TCN1

106

P20061
RVNYRELLLEHQDAY

GPLD1

46

P80108
LQDYDQARHYLLAAV

TTC9C

121

Q8N5M4
VERRFGQIHEYYLEQ

TSPYL6

226

Q8N831
GQIHEYYLEQRNDII

TSPYL6

231

Q8N831
QIYEYVEILGEQRHL

SF3A3

326

Q12874
DLGINYYRQAQHLAE

TTC37

781

Q6PGP7
AQNEEILYVLRHYIQ

UGGT2

206

Q9NYU1
GRHQYINEDEYEVNL

USP7

1046

Q93009
MYEGYLQHDAQEVLQ

USP1

191

O94782
NENERNFHIYYQLLE

MYO1F

201

O00160
QLLQEDRYENGYVHP

MSC

161

O60682