Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	HCN2 SCN1A SCN2A SCN8A HCN4	5.58e-06	26	202	5	GO:0005248
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3C RIMBP3 RIMBP3B	1.00e-05	5	202	3	GO:0030156
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	TET2 CYP1B1 CYP2D7 CYP11A1 AKR1C4 TBXAS1 CYP27C1 RSBN1 MICAL2 TET1	2.94e-05	194	202	10	GO:0016705
GeneOntologyMolecularFunction	iron ion binding	TET2 CYP1B1 CYP2D7 CYP11A1 ALOX15 TBXAS1 FA2H CYP27C1 TET1	5.00e-05	166	202	9	GO:0005506
GeneOntologyMolecularFunction	L-alanine:2-oxoglutarate aminotransferase activity	GPT2 GPT	1.02e-04	2	202	2	GO:0004021
GeneOntologyMolecularFunction	alanine-oxo-acid transaminase activity	GPT2 GPT	1.02e-04	2	202	2	GO:0047635
GeneOntologyMolecularFunction	monooxygenase activity	CYP1B1 CYP2D7 CYP11A1 AKR1C4 TBXAS1 CYP27C1 MICAL2	1.70e-04	115	202	7	GO:0004497
GeneOntologyMolecularFunction	sodium channel activity	HCN2 SCN1A SCN2A SCN8A HCN4	1.78e-04	52	202	5	GO:0005272
GeneOntologyMolecularFunction	5-methylcytosine dioxygenase activity	TET2 TET1	3.03e-04	3	202	2	GO:0070579
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN2A SCN8A	3.42e-04	14	202	3	GO:0031402
GeneOntologyMolecularFunction	phosphatidylinositol-3,4-bisphosphate phosphatase activity	INPP4A PTEN	6.03e-04	4	202	2	GO:0106017
GeneOntologyBiologicalProcess	supramolecular fiber organization	CYP1B1 EPPK1 SPAST MYO7B SPTA1 SYNPO2L MAP3K1 PGM5 SPTBN5 NF1 KRT20 HOOK2 DYNC1H1 ALOX15 FLNC KRT14 COMP KRT17 ADAMTS2 KRT28 ARHGEF5 DVL1 ASAP3 TRIM54 SPTBN4 USP8 MICAL2 PRKCE AKAP13	4.53e-08	957	199	29	GO:0097435
GeneOntologyBiologicalProcess	actin filament-based process	MYO7B CYTH2 SPTA1 SYNPO2L MAP3K1 PGM5 SPTBN5 NF1 SCN1A SCN2A AMOTL1 SCN8A ALOX15 AKAP6 FLNC CACNB2 HCN4 ARHGEF5 DVL2 ASAP3 DVL3 SPTBN4 MICAL2 TLN1 PRKCE AKAP13 IKBKB	2.21e-07	912	199	27	GO:0030029
GeneOntologyBiologicalProcess	positive regulation of neuron projection arborization	DVL1 DVL2 DVL3 GRIP1	5.71e-07	8	199	4	GO:0150012
GeneOntologyBiologicalProcess	membrane depolarization during action potential	HCN2 SCN1A SCN2A SCN8A CACNB2 HCN4	1.14e-06	36	199	6	GO:0086010
GeneOntologyBiologicalProcess	regulation of neuron projection arborization	DVL1 DVL2 DVL3 GRIP1	1.06e-05	15	199	4	GO:0150011
GeneOntologyBiologicalProcess	actin cytoskeleton organization	MYO7B CYTH2 SPTA1 SYNPO2L MAP3K1 PGM5 SPTBN5 NF1 AMOTL1 ALOX15 FLNC ARHGEF5 DVL2 ASAP3 DVL3 SPTBN4 MICAL2 TLN1 PRKCE AKAP13 IKBKB	3.46e-05	803	199	21	GO:0030036
GeneOntologyBiologicalProcess	negative regulation of keratinocyte migration	EPPK1 PTEN	9.26e-05	2	199	2	GO:0051548
GeneOntologyBiologicalProcess	regulation of actin filament-based process	SPTA1 SYNPO2L MAP3K1 SPTBN5 ALOX15 AKAP6 HCN4 ARHGEF5 DVL2 ASAP3 DVL3 SPTBN4 PRKCE AKAP13	9.56e-05	438	199	14	GO:0032970
GeneOntologyBiologicalProcess	regulation of membrane potential	PTEN HCN2 SLC39A8 SCN1A SCN2A SCN8A SLC17A7 AKAP6 CACNB2 CUX2 HCN4 NTRK3 ARL6IP5 DVL1 PRKCE NNT	1.11e-04	559	199	16	GO:0042391
GeneOntologyCellularComponent	supramolecular fiber	EPPK1 SPAST DCDC1 SYNPO2L MAP3K1 PGM5 SCN1A SCN8A KRT20 HOOK2 DNM1 DYNC1H1 FLNC KRT14 KRT17 KRT28 DVL1 DNAH2 TRIM54 INO80 TEK GRIP1 SPTBN4 MICAL2 AKAP13 TUBE1 MX1	2.11e-05	1179	199	27	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	EPPK1 SPAST DCDC1 SYNPO2L MAP3K1 PGM5 SCN1A SCN8A KRT20 HOOK2 DNM1 DYNC1H1 FLNC KRT14 KRT17 KRT28 DVL1 DNAH2 TRIM54 INO80 TEK GRIP1 SPTBN4 MICAL2 AKAP13 TUBE1 MX1	2.37e-05	1187	199	27	GO:0099081
GeneOntologyCellularComponent	node of Ranvier	SCN1A SCN2A SCN8A SPTBN4	3.43e-05	20	199	4	GO:0033268
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	EPPK1 SPAST DCDC1 MAP3K1 KRT20 HOOK2 DNM1 DYNC1H1 KRT14 KRT17 KRT28 DVL1 DNAH2 TRIM54 INO80 TEK GRIP1 SPTBN4 MICAL2 AKAP13 TUBE1 MX1	4.94e-05	899	199	22	GO:0099513
GeneOntologyCellularComponent	spectrin	SPTA1 SPTBN5 SPTBN4	6.84e-05	9	199	3	GO:0008091
GeneOntologyCellularComponent	manchette	RIMBP3C DYNC1H1 RIMBP3 RIMBP3B	1.36e-04	28	199	4	GO:0002177
GeneOntologyCellularComponent	axon initial segment	SCN1A SCN2A SCN8A SPTBN4	1.57e-04	29	199	4	GO:0043194
GeneOntologyCellularComponent	cell-cell contact zone	PGM5 SCN1A SCN2A NECTIN2 AKAP6 SPTBN4	2.80e-04	94	199	6	GO:0044291
GeneOntologyCellularComponent	axon	SPAST CYTH2 SPTA1 HCN2 NF1 SCN1A SCN2A SCN8A SLC17A7 SYT1 DNM1 DYNC1H1 CNTN1 HCN4 NTRK3 CANX DVL1 GRIP1 SPTBN4 CPLX3	3.44e-04	891	199	20	GO:0030424
GeneOntologyCellularComponent	intercalated disc	PGM5 SCN1A SCN2A AKAP6 SPTBN4	4.77e-04	68	199	5	GO:0014704
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN1A SCN2A SCN8A	5.24e-04	17	199	3	GO:0001518
GeneOntologyCellularComponent	HCN channel complex	HCN2 HCN4	5.34e-04	4	199	2	GO:0098855
GeneOntologyCellularComponent	cell-cell junction	EPPK1 CYTH3 CYTH2 PGM5 UBA1 SCN1A SCN2A AMOTL1 NECTIN2 C1QTNF5 AKAP6 TEK SPTBN4 STXBP6 TLN1	5.61e-04	591	199	15	GO:0005911
GeneOntologyCellularComponent	photoreceptor ribbon synapse	DNM1 CACNB2 CPLX3	6.24e-04	18	199	3	GO:0098684
GeneOntologyCellularComponent	R2TP complex	RUVBL2 PIH1D1	8.85e-04	5	199	2	GO:0097255
GeneOntologyCellularComponent	T-tubule	SCN1A SCN2A AKAP6 CACNB2 PRKCE	9.47e-04	79	199	5	GO:0030315
GeneOntologyCellularComponent	Weibel-Palade body	VWF ECE1	1.32e-03	6	199	2	GO:0033093
GeneOntologyCellularComponent	presynaptic membrane	SCN1A SCN2A SCN8A SYT1 DNM1 CNTN1 CANX GRIP1 CPLX3	1.39e-03	277	199	9	GO:0042734
GeneOntologyCellularComponent	main axon	SCN1A SCN2A SCN8A DNM1 SPTBN4	1.62e-03	89	199	5	GO:0044304
GeneOntologyCellularComponent	nuclear membrane	SPAST INPP4A QRICH2 AKAP6 CANX CREB3L4 SEPHS1 UTP18 SYNE3 MX1	1.96e-03	349	199	10	GO:0031965
GeneOntologyCellularComponent	clathrin-coated vesicle	SLC17A7 SYT1 DNM1 VWF DVL1 DVL2 APOB ECE1	2.01e-03	237	199	8	GO:0030136
GeneOntologyCellularComponent	glutamatergic synapse	INPP4A CYTH2 NF1 SCN2A SCN8A SYT1 DNM1 CNTN1 PSD2 NTRK3 CANX DVL1 DVL3 DGKE GRIP1 USP8 PRKCE	2.16e-03	817	199	17	GO:0098978
GeneOntologyCellularComponent	sarcolemma	PGM5 SCN1A SCN2A AKAP6 FLNC CACNB2 PRKCE	2.34e-03	190	199	7	GO:0042383
GeneOntologyCellularComponent	anchoring junction	EPPK1 CYTH3 CYTH2 PGM5 UBA1 SCN1A SCN2A AMOTL1 NECTIN2 C1QTNF5 AKAP6 FLNC ARHGEF5 ASAP3 TEK SPTBN4 STXBP6 SH3PXD2A TLN1	2.54e-03	976	199	19	GO:0070161
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN2A SCN8A	2.59e-03	29	199	3	GO:0034706
GeneOntologyCellularComponent	90S preribosome	NOL6 HEATR1 UTP18	2.59e-03	29	199	3	GO:0030686
GeneOntologyCellularComponent	nuclear envelope	SPAST INPP4A QRICH2 DYNC1H1 NPC1 AKAP6 CANX CREB3L4 SEPHS1 UTP18 SYNE3 NUP188 MX1	2.84e-03	560	199	13	GO:0005635
GeneOntologyCellularComponent	clathrin-sculpted glutamate transport vesicle membrane	SLC17A7 SYT1	3.11e-03	9	199	2	GO:0060203
GeneOntologyCellularComponent	clathrin-sculpted glutamate transport vesicle	SLC17A7 SYT1	3.11e-03	9	199	2	GO:0060199
GeneOntologyCellularComponent	Z disc	SYNPO2L PGM5 SCN1A SCN8A FLNC TRIM54	3.28e-03	151	199	6	GO:0030018
HumanPheno	Malformed lacrimal duct	FREM2 FRAS1 GRIP1	2.94e-06	3	74	3	HP:0007993
HumanPheno	Midline nasal groove	FREM2 FRAS1 GRIP1	1.17e-05	4	74	3	HP:0004112
HumanPheno	Bifid tongue	FREM2 FRAS1 DVL1 DVL3 GRIP1	2.39e-05	25	74	5	HP:0010297
HumanPheno	Generalized tonic seizure	HCN2 SCN1A SCN2A SCN8A DNM1 DMXL2 CUX2	3.28e-05	64	74	7	HP:0010818
HumanPheno	Cryptophthalmos	FREM2 FRAS1 GRIP1	5.71e-05	6	74	3	HP:0001126
HumanPheno	Cleft ala nasi	FREM2 FRAS1 GRIP1	5.71e-05	6	74	3	HP:0003191
HumanPheno	Laryngeal stenosis	FREM2 FRAS1 LAMC2 GRIP1	6.55e-05	16	74	4	HP:0001602
HumanPheno	Wide pubic symphysis	FREM2 FRAS1 GRIP1	9.88e-05	7	74	3	HP:0003183
HumanPheno	Female pseudohermaphroditism	FREM2 FRAS1 GRIP1	9.88e-05	7	74	3	HP:0010458
MousePheno	postnatal lethality, complete penetrance	INPP4A SPEG SPTA1 ADK NF1 SCN1A SCN2A AFG3L2 SCN8A SYT1 DNM1 CNTN1 FRAS1 KRT14 NTRK3 DVL3 LAMC2	1.16e-05	445	158	17	MP:0011085
MousePheno	abnormal truncus arteriosus septation	NF1 CPLANE1 NTRK3 DVL2 DVL3 ECE1 SH3PXD2A	4.51e-05	84	158	7	MP:0010454
MousePheno	abnormal ductus venosus morphology	TULP4 SYT1 DMXL2 TRIM45 ARNT SH3PXD2A	4.72e-05	58	158	6	MP:0013873
MousePheno	impaired limb coordination	SCN8A DNM1 DYNC1H1 CNTN1 NTRK3 RORB	5.21e-05	59	158	6	MP:0001524
MousePheno	ectopic manchette	SPAST RIMBP3C RIMBP3 RIMBP3B	5.33e-05	19	158	4	MP:0009377
MousePheno	persistent truncus arteriosus	NF1 CPLANE1 DVL2 DVL3 ECE1 SH3PXD2A	1.07e-04	67	158	6	MP:0002633
MousePheno	abnormal aorticopulmonary septum morphology	NF1 CPLANE1 DVL2 DVL3 ECE1 SH3PXD2A	1.16e-04	68	158	6	MP:0010650
MousePheno	aorticopulmonary septal defect	NF1 CPLANE1 DVL2 DVL3 ECE1 SH3PXD2A	1.16e-04	68	158	6	MP:0010651
MousePheno	abnormal heart septum morphology	SLC39A8 FREM2 NF1 TULP4 SCN8A SYT1 CPLANE1 FRAS1 NTRK3 DVL2 DVL3 ECE1 TRIM45 SH3PXD2A	1.30e-04	388	158	14	MP:0006113
MousePheno	blistering	FRAS1 KRT14 LAMC2 GRIP1	1.40e-04	24	158	4	MP:0001208
MousePheno	clubfoot	FREM2 FRAS1 GRIP1	1.60e-04	10	158	3	MP:0000576
Domain	Dishevelled	DVL1P1 DVL1 DVL2 DVL3	1.20e-08	4	197	4	PF02377
Domain	Dishevelled_fam	DVL1P1 DVL1 DVL2 DVL3	1.20e-08	4	197	4	IPR008339
Domain	Dishevelled_protein_dom	DVL1P1 DVL1 DVL2 DVL3	1.20e-08	4	197	4	IPR003351
Domain	DIX	DVL1P1 DVL1 DVL2 DVL3	4.10e-07	7	197	4	PF00778
Domain	DIX	DVL1P1 DVL1 DVL2 DVL3	4.10e-07	7	197	4	IPR001158
Domain	DIX	DVL1P1 DVL1 DVL2 DVL3	4.10e-07	7	197	4	PS50841
Domain	DAX	DVL1P1 DVL1 DVL2 DVL3	4.10e-07	7	197	4	SM00021
Domain	Dishevelled_C-dom	DVL1 DVL2 DVL3	1.16e-06	3	197	3	IPR024580
Domain	Dsh_C	DVL1 DVL2 DVL3	1.16e-06	3	197	3	PF12316
Domain	Dsh/Dvl-rel	DVL1 DVL2 DVL3	4.59e-06	4	197	3	IPR015506
Domain	SPEC	SPTA1 SPTBN5 AKAP6 SPTBN4 SYNE3	1.98e-05	32	197	5	SM00150
Domain	Spectrin/alpha-actinin	SPTA1 SPTBN5 AKAP6 SPTBN4 SYNE3	1.98e-05	32	197	5	IPR018159
Domain	Na_trans_cytopl	SCN1A SCN2A SCN8A	2.26e-05	6	197	3	PF11933
Domain	Na_trans_cytopl	SCN1A SCN2A SCN8A	2.26e-05	6	197	3	IPR024583
Domain	DEP	DVL1P1 DVL1 DVL2 DVL3	7.57e-05	22	197	4	PF00610
Domain	DEP	DVL1P1 DVL1 DVL2 DVL3	7.57e-05	22	197	4	PS50186
Domain	DEP	DVL1P1 DVL1 DVL2 DVL3	7.57e-05	22	197	4	SM00049
Domain	DEP_dom	DVL1P1 DVL1 DVL2 DVL3	9.09e-05	23	197	4	IPR000591
Domain	Spectrin	SPTA1 SPTBN5 SPTBN4 SYNE3	9.09e-05	23	197	4	PF00435
Domain	PH_dom-spectrin-type	SPTBN5 PSD2 SPTBN4	9.26e-05	9	197	3	IPR001605
Domain	Tet_JBP	TET2 TET1	1.11e-04	2	197	2	PF12851
Domain	2OGFeDO_noxygenase_dom	TET2 TET1	1.11e-04	2	197	2	IPR024779
Domain	ARHGEF5_35	ARHGEF5 ARHGEF35	1.11e-04	2	197	2	PF15441
Domain	ARHGEF5/35_N	ARHGEF5 ARHGEF35	1.11e-04	2	197	2	IPR029212
Domain	RSBN1	RSBN1 RSBN1L	1.11e-04	2	197	2	IPR026306
Domain	DVL-1	DVL1P1 DVL1	1.11e-04	2	197	2	IPR008340
Domain	Tet_JBP	TET2 TET1	1.11e-04	2	197	2	SM01333
Domain	Na_channel_asu	SCN1A SCN2A SCN8A	1.31e-04	10	197	3	IPR001696
Domain	IG_FLMN	FLNC TRIM71 TRIM45	1.31e-04	10	197	3	SM00557
Domain	Na_trans_assoc	SCN1A SCN2A SCN8A	1.31e-04	10	197	3	IPR010526
Domain	Na_trans_assoc	SCN1A SCN2A SCN8A	1.31e-04	10	197	3	PF06512
Domain	PH	ARHGAP42 CYTH3 CYTH2 SPTBN5 DNM1 PSD2 ARHGEF5 ASAP3 SPTBN4 AKAP13	1.65e-04	229	197	10	PF00169
Domain	Filamin	FLNC TRIM71 TRIM45	1.79e-04	11	197	3	PF00630
Domain	ZF_CXXC	KMT2B TET1 CXXC4	1.79e-04	11	197	3	PS51058
Domain	FILAMIN_REPEAT	FLNC TRIM71 TRIM45	1.79e-04	11	197	3	PS50194
Domain	Filamin/ABP280_rpt	FLNC TRIM71 TRIM45	1.79e-04	11	197	3	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNC TRIM71 TRIM45	1.79e-04	11	197	3	IPR017868
Domain	Znf_CXXC	KMT2B TET1 CXXC4	1.79e-04	11	197	3	IPR002857
Domain	zf-CXXC	KMT2B TET1 CXXC4	1.79e-04	11	197	3	PF02008
Domain	Spectrin_repeat	SPTA1 SPTBN5 SPTBN4 SYNE3	2.32e-04	29	197	4	IPR002017
Domain	-	CYTH3 CYTH2 PSD2	4.79e-04	15	197	3	1.10.1000.11
Domain	Sec7	CYTH3 CYTH2 PSD2	4.79e-04	15	197	3	PF01369
Domain	Sec7_alpha_orthog	CYTH3 CYTH2 PSD2	4.79e-04	15	197	3	IPR023394
Domain	SH3	ARHGAP42 MYO7B SPTA1 RIMBP3C CACNB2 ARHGEF5 RIMBP3 SH3PXD2A RIMBP3B	4.92e-04	216	197	9	SM00326
Domain	SH3	ARHGAP42 MYO7B SPTA1 RIMBP3C CACNB2 ARHGEF5 RIMBP3 SH3PXD2A RIMBP3B	4.92e-04	216	197	9	PS50002
Domain	SH3_domain	ARHGAP42 MYO7B SPTA1 RIMBP3C CACNB2 ARHGEF5 RIMBP3 SH3PXD2A RIMBP3B	5.61e-04	220	197	9	IPR001452
Domain	SEC7	CYTH3 CYTH2 PSD2	5.85e-04	16	197	3	PS50190
Domain	Sec7	CYTH3 CYTH2 PSD2	5.85e-04	16	197	3	SM00222
Domain	Sec7_dom	CYTH3 CYTH2 PSD2	5.85e-04	16	197	3	IPR000904
Domain	Ion_trans_N	HCN2 HCN4	6.55e-04	4	197	2	IPR013621
Domain	Ion_trans_N	HCN2 HCN4	6.55e-04	4	197	2	PF08412
Domain	PH	ARHGAP42 CYTH3 CYTH2 SPTBN5 DNM1 PSD2 ARHGEF5 ASAP3 SPTBN4 AKAP13	7.62e-04	278	197	10	SM00233
Domain	PH_DOMAIN	ARHGAP42 CYTH3 CYTH2 SPTBN5 DNM1 PSD2 ARHGEF5 ASAP3 SPTBN4 AKAP13	7.83e-04	279	197	10	PS50003
Domain	PH_domain	ARHGAP42 CYTH3 CYTH2 SPTBN5 DNM1 PSD2 ARHGEF5 ASAP3 SPTBN4 AKAP13	8.05e-04	280	197	10	IPR001849
Domain	-	ARHGAP42 MYO7B CYTH3 CYTH2 SPTBN5 DNM1 PSD2 ARHGEF5 ASAP3 SPTBN4 TLN1 AKAP13	9.43e-04	391	197	12	2.30.29.30
Domain	VWC_out	SSPOP FRAS1 VWF	9.89e-04	19	197	3	SM00215
Domain	Keratin_I	KRT20 KRT14 KRT17 KRT28	1.17e-03	44	197	4	IPR002957
Domain	Cyt_P450_E_grp-I	CYP1B1 CYP11A1 TBXAS1 CYP27C1	1.28e-03	45	197	4	IPR002401
Domain	SH3_9	ARHGAP42 RIMBP3C ARHGEF5 RIMBP3 RIMBP3B	1.40e-03	78	197	5	PF14604
Domain	Dynamin_central	DNM1 MX1	1.61e-03	6	197	2	IPR000375
Domain	GED	DNM1 MX1	1.61e-03	6	197	2	SM00302
Domain	Dynamin_M	DNM1 MX1	1.61e-03	6	197	2	PF01031
Domain	GED_dom	DNM1 MX1	1.61e-03	6	197	2	IPR020850
Domain	GED	DNM1 MX1	1.61e-03	6	197	2	PS51388
Domain	Dynamin_GTPase_CS	DNM1 MX1	1.61e-03	6	197	2	IPR019762
Domain	GED	DNM1 MX1	1.61e-03	6	197	2	PF02212
Domain	GED	DNM1 MX1	1.61e-03	6	197	2	IPR003130
Domain	FN3_dom	EPHB3 SPEG RIMBP3C CNTN1 FLNC TEK RIMBP3 RIMBP3B	1.73e-03	209	197	8	IPR003961
Domain	ACTININ_2	SPTBN5 FLNC SPTBN4	1.75e-03	23	197	3	PS00020
Domain	ACTININ_1	SPTBN5 FLNC SPTBN4	1.75e-03	23	197	3	PS00019
Domain	Actinin_actin-bd_CS	SPTBN5 FLNC SPTBN4	1.75e-03	23	197	3	IPR001589
Domain	PH_dom-like	ARHGAP42 MYO7B CYTH3 CYTH2 SPTBN5 DNM1 PSD2 ARHGEF5 ASAP3 SPTBN4 TLN1 AKAP13	1.95e-03	426	197	12	IPR011993
Domain	SH3_2	MYO7B RIMBP3C ARHGEF5 RIMBP3 RIMBP3B	2.17e-03	86	197	5	PF07653
Domain	SH3_2	MYO7B RIMBP3C ARHGEF5 RIMBP3 RIMBP3B	2.17e-03	86	197	5	IPR011511
Domain	G_DYNAMIN_1	DNM1 MX1	2.24e-03	7	197	2	PS00410
Domain	DYNc	DNM1 MX1	2.24e-03	7	197	2	SM00053
Domain	Cyt_P450_CS	CYP1B1 CYP11A1 TBXAS1 CYP27C1	2.35e-03	53	197	4	IPR017972
Pathway	REACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_DVL_INTERACTING_PROTEINS	DVL1 DVL2 DVL3 CXXC4	6.62e-08	5	153	4	M27447
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTA1 SPTBN5 SCN1A SCN2A SCN8A SPTBN4	8.72e-07	31	153	6	M877
Pathway	PID_BETA_CATENIN_DEG_PATHWAY	SSPOP DVL1 DVL2 DVL3	3.63e-05	18	153	4	M31
Pathway	REACTOME_L1CAM_INTERACTIONS	SPTA1 SPTBN5 SCN1A SCN2A SCN8A DNM1 CNTN1 SPTBN4	5.12e-05	121	153	8	M872
Pathway	REACTOME_WNT_MEDIATED_ACTIVATION_OF_DVL	DVL1 DVL2 DVL3	6.75e-05	8	153	3	M27100
Pathway	REACTOME_WNT_MEDIATED_ACTIVATION_OF_DVL	DVL1 DVL2 DVL3	1.00e-04	9	153	3	MM14792
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTA1 SPTBN5 SPTBN4	1.42e-04	10	153	3	MM15112
Pubmed	cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene.	DVL1P1 DVL1 DVL2 DVL3	1.22e-09	4	207	4	8817329
Pubmed	Human dishevelled genes constitute a DHR-containing multigene family.	DVL1P1 DVL1 DVL2 DVL3	1.22e-09	4	207	4	9192851
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPPK1 KMT2B CYTH3 SPEG TULP4 GLI1 CSAD SCN8A KBTBD11 NLRC5 DYNC1H1 NPC1 FLNC FRAS1 DVL1 MIB2 INO80 MLXIP ECE1 C8orf58 SBNO2 SYNE3 TLN1 TMEM268 AKAP13 NUP188	2.79e-09	1105	207	26	35748872
Pubmed	GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation.	PTEN DNM1 DVL1 DVL2 DVL3	5.72e-08	18	207	5	25073924
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	SPTA1 SPTBN5 FLNC SPTBN4 TLN1	5.72e-08	18	207	5	12119179
Pubmed	Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay.	DVL1 DVL2 DVL3	2.08e-07	3	207	3	27744318
Pubmed	Where is the spike generator of the cochlear nerve? Voltage-gated sodium channels in the mouse cochlea.	SCN2A SCN8A SPTBN4	2.08e-07	3	207	3	16033895
Pubmed	Dishevelled proteins are significantly upregulated in chronic lymphocytic leukaemia.	DVL1 DVL2 DVL3	2.08e-07	3	207	3	27086035
Pubmed	Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.	SCN1A SCN2A SCN8A	2.08e-07	3	207	3	28518218
Pubmed	Insertional mutation of the motor endplate disease (med) locus on mouse chromosome 15.	SCN8A SYT1 CNTN1	2.08e-07	3	207	3	7601440
Pubmed	Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3.	DVL1 DVL2 DVL3	2.08e-07	3	207	3	18093802
Pubmed	DVL mutations identified from human neural tube defects and Dandy-Walker malformation obstruct the Wnt signaling pathway.	DVL1 DVL2 DVL3	2.08e-07	3	207	3	32900645
Pubmed	Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency.	TET2 KMT2B TET1	2.08e-07	3	207	3	31844322
Pubmed	Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.	SCN1A SCN2A SCN8A	2.08e-07	3	207	3	32845893
Pubmed	Dishevelled-3 C-terminal His single amino acid repeats are obligate for Wnt5a activation of non-canonical signaling.	DVL1 DVL2 DVL3	2.08e-07	3	207	3	21092292
Pubmed	Genomic organization of mouse Dishevelled genes.	DVL1 DVL2 DVL3	2.08e-07	3	207	3	8973355
Pubmed	Dishevelled family proteins are expressed in non-small cell lung cancer and function differentially on tumor progression.	DVL1 DVL2 DVL3	2.08e-07	3	207	3	18692936
Pubmed	Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.	SCN1A SCN2A SCN8A	2.08e-07	3	207	3	17928448
Pubmed	Transcriptional control of pacemaker channel genes HCN2 and HCN4 by Sp1 and implications in re-expression of these genes in hypertrophied myocytes.	SP1 HCN2 HCN4	2.08e-07	3	207	3	19471099
Pubmed	Dishevelled proteins are associated with olfactory sensory neuron presynaptic terminals.	DVL1 DVL2 DVL3	2.08e-07	3	207	3	23437169
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	MAGEA8 SP1 EPPK1 ACACB MAP3K1 TULP4 SCN1A DYNC1H1 CUX2 ARHGEF5 ASAP3 KIAA1671 TLN1 AKAP13	3.53e-07	430	207	14	35044719
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	NOL6 RUVBL2 FREM2 AFG3L2 HOOK2 DNM1 DMXL2 FRAS1 RNF31 ARHGEF5 LAMC2 MIB2 ECE1 SBNO2 ARNT AKAP13 RSBN1L	4.24e-07	650	207	17	38777146
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RALGAPA1 INPP4A CYTH2 SPTA1 LRRC47 UBA1 NF1 SCN2A AFG3L2 KBTBD11 SLC17A7 SYT1 DNM1 VARS1 DYNC1H1 CNTN1 FLNC CACNB2 DMXL2 KRT14 VWF SPTBN4 USO1 MICAL2 TLN1 PRKCE	4.62e-07	1431	207	26	37142655
Pubmed	Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the Wnt signaling pathway.	DVL1 DVL2 DVL3	8.28e-07	4	207	3	24643799
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN2A SCN8A	8.28e-07	4	207	3	17537961
Pubmed	DCDC2 mutations cause a renal-hepatic ciliopathy by disrupting Wnt signaling.	DVL1 DVL2 DVL3	8.28e-07	4	207	3	25557784
Pubmed	Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.	SCN1A SCN2A SCN8A	8.28e-07	4	207	3	35031483
Pubmed	Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.	SCN1A SCN2A SCN8A	8.28e-07	4	207	3	29578003
Pubmed	Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.	SCN1A SCN2A SCN8A	8.28e-07	4	207	3	21156207
Pubmed	Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation.	DVL1 DVL2 DVL3	8.28e-07	4	207	3	18772438
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3C RIMBP3 RIMBP3B	8.28e-07	4	207	3	19091768
Pubmed	Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein.	DVL1 DVL2 DVL3	8.28e-07	4	207	3	19465938
Pubmed	Frem1 activity is regulated by Sonic hedgehog signaling in the cranial neural crest mesenchyme during midfacial morphogenesis.	FREM2 GLI1 FRAS1	8.28e-07	4	207	3	36495293
Pubmed	Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein.	DVL1 DVL3 CXXC4	8.28e-07	4	207	3	11113207
Pubmed	Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways.	DVL1 DVL2 DVL3	8.28e-07	4	207	3	19625296
Pubmed	Loss of Dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus.	DVL1 DVL2 DVL3	8.28e-07	4	207	3	25043421
Pubmed	Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling.	DVL1 DVL2 DVL3	8.28e-07	4	207	3	23371553
Pubmed	Activation of p53 by Dishevelled independent of Wnt or planar polarity pathways.	DVL1 DVL2 DVL3	8.28e-07	4	207	3	17593335
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	EPPK1 NOL6 RUVBL2 PGRMC1 UBA1 NF1 AFG3L2 DDX54 ASCC3 PHIP VARS1 DYNC1H1 FLNC KRT14 KRT17 CANX HEATR1 KIAA1671 TLN1 NUP188 NNT	9.66e-07	1024	207	21	24711643
Pubmed	Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family.	DVL1 DVL2 DVL3	2.06e-06	5	207	3	15456783
Pubmed	The E3 ubiquitin ligase ITCH negatively regulates canonical Wnt signaling by targeting dishevelled protein.	DVL1 DVL2 DVL3	2.06e-06	5	207	3	22826439
Pubmed	A novel Wnt5a-Frizzled4 signaling pathway mediates activity-independent dendrite morphogenesis via the distal PDZ motif of Frizzled 4.	DVL1 DVL2 DVL3	2.06e-06	5	207	3	25424568
Pubmed	CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation.	DVL1 DVL2 DVL3	2.06e-06	5	207	3	24469800
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3C RIMBP3 RIMBP3B	2.06e-06	5	207	3	17855024
Pubmed	Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development.	GLI1 KRT14 KRT17 LAMC2	2.10e-06	16	207	4	12533516
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	EPPK1 NOL6 GFPT1 LRRC47 NF1 DDX54 ASCC3 PHIP DYNC1H1 FLNC CANX HEATR1 UTP18 TLN1 NUP188 NNT	2.18e-06	653	207	16	22586326
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	KMT2B SSPOP QRICH2 GFPT1 LRRC47 FREM2 SCN8A KRT20 DYNC1H1 KRT28 CANX DNAH2 KIAA1671 TLN1 AKAP13 NUP188 TUBE1	2.30e-06	736	207	17	29676528
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	EPPK1 SPTA1 RUVBL2 GFPT1 AFG3L2 GPT2 FLNC CANX GPT IKBKB NNT	2.38e-06	304	207	11	32235678
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	CYTH3 UBA1 SYT1 DNM1 DYNC1H1 CNTN1 CACNB2 DMXL2 SPTBN4 PRKCE	2.95e-06	251	207	10	27507650
Pubmed	A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.	FREM2 FRAS1 LAMC2 GRIP1	3.49e-06	18	207	4	14730302
Pubmed	Targeting E3 Ubiquitin Ligase WWP1 Prevents Cardiac Hypertrophy Through Destabilizing DVL2 via Inhibition of K27-Linked Ubiquitination.	DVL1 DVL2 DVL3	4.10e-06	6	207	3	34139860
Pubmed	Mild recessive mutations in six Fraser syndrome-related genes cause isolated congenital anomalies of the kidney and urinary tract.	FREM2 FRAS1 GRIP1	4.10e-06	6	207	3	24700879
Pubmed	Deletion of the Dishevelled family of genes disrupts anterior-posterior axis specification and selectively prevents mesoderm differentiation.	DVL1 DVL2 DVL3	4.10e-06	6	207	3	32579954
Pubmed	Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1.	FREM2 FRAS1 GRIP1	4.10e-06	6	207	3	17462874
Pubmed	Nuclear factor of activated T cells (NFAT) proteins repress canonical Wnt signaling via its interaction with Dishevelled (Dvl) protein and participate in regulating neural progenitor cell proliferation and differentiation.	DVL1 DVL2 DVL3	4.10e-06	6	207	3	21880741
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN1A SCN2A SCN8A	4.10e-06	6	207	3	23652591
Pubmed	A large-scale standardized physiological survey reveals functional organization of the mouse visual cortex.	SLC17A7 CUX2 RORB	4.10e-06	6	207	3	31844315
Pubmed	SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling.	DVL1 DVL2 DVL3	4.10e-06	6	207	3	20439735
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	PGRMC1 UBA1 DNM1 VARS1 DYNC1H1 DMXL2 CYP27C1 CANX ASAP3 ECE1 TLN1	4.13e-06	322	207	11	26514267
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RALGAPA1 TET2 SPAST SPICE1 NF1 NECTIN2 ARHGEF5 NTRK3 ALPK1 MLXIP KIAA1671 GRIP1 USP8 USO1 SH3PXD2A TET1 PRKCE AKAP13	4.59e-06	861	207	18	36931259
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	SPTA1 RUVBL2 DNM1 HSPA6 HSPA7 VARS1 DYNC1H1 KRT14 KRT17 ASAP3	4.93e-06	266	207	10	19380743
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	RALGAPA1 RUVBL2 GFPT1 SPICE1 UBA1 NECTIN2 AFG3L2 ASCC3 DYNC1H1 CANX ARL6IP5 GNB1L DVL2 GRIP1 USO1 TLN1	6.05e-06	708	207	16	39231216
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	TET2 EPPK1 KMT2B RUVBL2 PGRMC1 GFPT1 LRRC47 DDX54 C3 VARS1 DYNC1H1 KRT14 KRT17 CANX HEATR1 TLN1	6.38e-06	711	207	16	33022573
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	SP100 EPPK1 NOL6 RUVBL2 GFPT1 LRRC47 UBA1 AMOTL1 AFG3L2 DDX54 C3 ASCC3 DYNC1H1 KRT14 KRT17 CANX LAMC2 HEATR1 KIAA1671 HARS2 UTP18 RSBN1L	6.80e-06	1257	207	22	36526897
Pubmed	Aberrant Cortical Activity in Multiple GCaMP6-Expressing Transgenic Mouse Lines.	SLC17A7 CUX2 RORB	7.15e-06	7	207	3	28932809
Pubmed	Dishevelled proteins regulate cell adhesion in mouse blastocyst and serve to monitor changes in Wnt signaling.	DVL1 DVL2 DVL3	7.15e-06	7	207	3	17005174
Pubmed	Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.	SCN1A SCN2A SCN8A	7.15e-06	7	207	3	25818041
Pubmed	Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells.	DVL1 DVL2 DVL3	7.15e-06	7	207	3	10806215
Pubmed	Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development.	DVL1 DVL2 DVL3	7.15e-06	7	207	3	19008950
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	SPTA1 PTEN UBA1 AFG3L2 SYNE3 MICAL2 PALM3 AKAP13	8.10e-06	168	207	8	30631154
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TET2 KMT2B ACACB INPP4A ASCC3 HSPA6 DVL1 DVL2 DVL3 KIAA1671 USO1 TET1	8.84e-06	418	207	12	34709266
Pubmed	Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth.	DVL1 DVL2 DVL3	1.14e-05	8	207	3	15454084
Pubmed	G alpha o mediates WNT-JNK signaling through dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells.	MAP3K1 DVL1 DVL3	1.14e-05	8	207	3	18187455
Pubmed	Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteins.	DVL1 DVL2 DVL3	1.14e-05	8	207	3	19388021
Pubmed	All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases.	DVL1 DVL2 DACT3	1.14e-05	8	207	3	21718540
Pubmed	Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1.	DVL1 DVL2 DVL3	1.14e-05	8	207	3	12165471
Pubmed	Atmin mediates kidney morphogenesis by modulating Wnt signaling.	GLI1 DVL1 DVL2 DVL3	1.18e-05	24	207	4	24852369
Pubmed	Regulation of planar cell polarity by Smurf ubiquitin ligases.	PTEN DVL1 DVL2 DVL3	1.40e-05	25	207	4	19379695
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	HGH1 PGRMC1 GFPT1 LRRC47 NECTIN2 ASCC3 HSPA6 VARS1 DYNC1H1 NPC1 CANX DVL2 DNAH2 DGKE HEATR1 USO1 TLN1 NUP188	1.54e-05	942	207	18	31073040
Pubmed	Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.	SCN1A SCN2A SCN8A	1.70e-05	9	207	3	15746173
Pubmed	Regulation of the Wnt signaling pathway by disabled-2 (Dab2).	DVL1 DVL2 DVL3	1.70e-05	9	207	3	12805222
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN1A SCN2A SCN8A	1.70e-05	9	207	3	16382098
Pubmed	Expression of planar cell polarity genes during development of the mouse CNS.	DVL1 DVL2 DVL3	1.70e-05	9	207	3	16487141
Pubmed	RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.	DVL1 DVL2 DVL3	1.70e-05	9	207	3	32965059
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SP100 ACACB TTC16 SPTA1 NOL6 KRT20 HSPA6 VARS1 FLNC FOXRED1 CUX2 KRT14 KRT17 DNAH2 APOB HEATR1 ECE1 SPTBN4 USP8 SEPHS1 UTP18 STS SH3PXD2A	1.84e-05	1442	207	23	35575683
Pubmed	Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.	PGRMC1 C3 DYNC1H1 KRT14 APOB TLN1	1.93e-05	92	207	6	37343697
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CYTH3 CYTH2 ARMCX4 HCN2 SPICE1 UBA1 NF1 SYT1 DNM1 DYNC1H1 CNTN1 CACNB2 DMXL2 HCN4 CANX DVL2 SPTBN4 PRKCE	2.07e-05	963	207	18	28671696
Pubmed	Essential role for Sonic hedgehog during hair follicle morphogenesis.	GLI1 KRT14 KRT17	2.42e-05	10	207	3	9882493
Pubmed	DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.	KMT2B TET1 CXXC4	2.42e-05	10	207	3	29276034
Pubmed	Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract.	DVL1 DVL2 DVL3	2.42e-05	10	207	3	15637299
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	FREM2 FRAS1 LAMC2 GRIP1	2.58e-05	29	207	4	22613833
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KMT2B RUVBL2 UBA1 AMOTL1 ASCC3 HSPA6 DYNC1H1 DVL1 HEATR1 KIAA1671 TLN1 TET1 RSBN1L	2.85e-05	549	207	13	38280479
Pubmed	Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.	EPHB3 CYP1B1 PTEN NECTIN2 FRAS1 CUX2 KRT14 DVL1 APOB ARNT	3.26e-05	331	207	10	20634891
Pubmed	Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription.	DVL1 DVL2 DVL3	3.31e-05	11	207	3	10644691
Pubmed	USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification.	AMOTL1 NPC1 DVL1 DVL2 DVL3	3.50e-05	62	207	5	31340145
Pubmed	Compartmental distribution of hyperpolarization-activated cyclic-nucleotide-gated channel 2 and hyperpolarization-activated cyclic-nucleotide-gated channel 4 in thalamic reticular and thalamocortical relay neurons.	HCN2 HCN4	3.53e-05	2	207	2	16806719
Pubmed	Distributive Processing by the Iron(II)/α-Ketoglutarate-Dependent Catalytic Domains of the TET Enzymes Is Consistent with Epigenetic Roles for Oxidized 5-Methylcytosine Bases.	TET2 TET1	3.53e-05	2	207	2	27362828
Pubmed	Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.	SCN1A SCN8A	3.53e-05	2	207	2	37901435
Pubmed	Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells.	TET2 TET1	3.53e-05	2	207	2	23415914
Pubmed	BerEp4, cytokeratin 14, and cytokeratin 17 immunohistochemical staining aid in differentiation of basaloid squamous cell carcinoma from basal cell carcinoma with squamous metaplasia.	KRT14 KRT17	3.53e-05	2	207	2	24168496
Interaction	ZNF683 interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	2.45e-08	10	204	5	int:ZNF683
Interaction	CELF4 interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	4.45e-08	11	204	5	int:CELF4
Interaction	BEND2 interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	7.57e-08	12	204	5	int:BEND2
Interaction	ZCCHC14 interactions	TET2 PRR20C PRR20D PRR20B PRR20E PRR20A SYNE3	7.82e-08	37	204	7	int:ZCCHC14
Interaction	PTTG2 interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	1.88e-07	14	204	5	int:PTTG2
Interaction	MBNL3 interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	4.04e-07	16	204	5	int:MBNL3
Interaction	HLX interactions	PRR20C PRR20D PRR20B PRR20E PRR20A SEPHS1	1.79e-06	37	204	6	int:HLX
Interaction	PRR34 interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	1.80e-06	21	204	5	int:PRR34
Interaction	TPRX1 interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	1.80e-06	21	204	5	int:TPRX1
Interaction	PRR35 interactions	SMUG1 PRR20C PRR20D PRR20B PRR20E HOOK2 PRR20A TRIM54	1.98e-06	83	204	8	int:PRR35
Interaction	KRT8 interactions	EPPK1 DCDC1 SPICE1 GLI1 PAN2 KRT20 PIH1D1 KRT14 KRT17 RNF31 ZNF484 KRT28 DVL1 TRIM54 KIAA1671 PRKCE NUP188	2.73e-06	441	204	17	int:KRT8
Interaction	SMAP1 interactions	SPAST PRR20C PRR20D PRR20B PRR20E PIH1D1 PRR20A	5.11e-06	67	204	7	int:SMAP1
Interaction	C3orf36 interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	5.60e-06	26	204	5	int:C3orf36
Interaction	TBX3 interactions	SP100 PRR20C PRR20D PRR20B PRR20E AFG3L2 PRR20A	6.23e-06	69	204	7	int:TBX3
Interaction	SP4 interactions	SP1 PRR20C PRR20D PRR20B PRR20E PRR20A	6.68e-06	46	204	6	int:SP4
Interaction	ZNF385C interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	1.91e-05	33	204	5	int:ZNF385C
Interaction	FAM9A interactions	PRR20C PRR20D PRR20B PRR20E PRR20A TRIM54	2.88e-05	59	204	6	int:FAM9A
Interaction	KRT79 interactions	GLI1 KRT20 KRT14 KRT17 KRT28 TRIM54	2.88e-05	59	204	6	int:KRT79
Interaction	CABP2 interactions	PRR20C PRR20D PRR20B PRR20E HOOK2 PRR20A	3.49e-05	61	204	6	int:CABP2
Interaction	C10orf55 interactions	SMUG1 PRR20C PRR20D PRR20B PRR20E PRR20A	5.02e-05	65	204	6	int:C10orf55
Interaction	ZNF488 interactions	HSPA6 PRR20A RIMBP3 USO1	5.33e-05	21	204	4	int:ZNF488
Interaction	SCN4B interactions	SCN1A SCN2A SCN8A	5.51e-05	8	204	3	int:SCN4B
Interaction	TBX6 interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	5.64e-05	41	204	5	int:TBX6
Interaction	FAM222B interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	6.35e-05	42	204	5	int:FAM222B
Interaction	YWHAQ interactions	RALGAPA1 TET2 EPPK1 SPEG SPTA1 RUVBL2 MAP3K1 NF1 NECTIN2 PIH1D1 VARS1 DYNC1H1 KRT17 ARHGEF5 ARL6IP5 DVL2 MLXIP KIAA1671 GRIP1 USP8 USO1 SH3PXD2A TLN1 TET1 PRKCE AKAP13	6.60e-05	1118	204	26	int:YWHAQ
Interaction	SAMD11 interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	7.12e-05	43	204	5	int:SAMD11
Interaction	BICRAL interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	7.12e-05	43	204	5	int:BICRAL
Interaction	SYNGAP1 interactions	ARHGAP42 CYTH2 RUVBL2 AFG3L2 KBTBD11 DNM1 DYNC1H1 CACNB2 DMXL2 NTRK3 PRKCE AKAP13	7.29e-05	307	204	12	int:SYNGAP1
Interaction	TRIM35 interactions	PRR20C PRR20D PRR20B PRR20E PAN2 RNF31 PRR20A	8.56e-05	103	204	7	int:TRIM35
Interaction	RHOXF2 interactions	PRR20C PRR20D PRR20B PRR20E RNF31 DVL2 PRR20A	9.10e-05	104	204	7	int:RHOXF2
Interaction	VENTX interactions	SP1 SMUG1 PRR20C PRR20D PRR20B PRR20E PRR20A	9.10e-05	104	204	7	int:VENTX
Interaction	KRT18 interactions	SP1 EPPK1 SPICE1 UBA1 PAN2 KRT20 PIH1D1 CNTN1 KRT14 KRT17 RNF31 KIAA1671 PRKCE NUP188	9.94e-05	419	204	14	int:KRT18
Interaction	FAM168A interactions	PRR20C PRR20D PRR20B TULP4 PRR20E AMOTL1 DVL2 PRR20A	1.01e-04	142	204	8	int:FAM168A
Interaction	GLIS2 interactions	PRR20C PRR20D PRR20B PRR20E PRR20A ARNT USO1	1.03e-04	106	204	7	int:GLIS2
Interaction	KRTAP19-1 interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	1.10e-04	47	204	5	int:KRTAP19-1
Interaction	FOXH1 interactions	PRR20C PRR20D PRR20B PRR20E VARS1 PRR20A HEATR1	1.22e-04	109	204	7	int:FOXH1
Interaction	DVL3 interactions	PRR20C PRR20D PRR20B PRR20E DDX54 CANX DVL1 DVL2 DVL3 PRR20A TRIM54	1.39e-04	280	204	11	int:DVL3
Interaction	OXER1 interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	1.48e-04	50	204	5	int:OXER1
Interaction	KRT1 interactions	PAN2 HOOK2 PIH1D1 KRT14 KRT17 RNF31 KRT28 DVL2 TRIM54 PRKCE	1.63e-04	238	204	10	int:KRT1
Interaction	RIPPLY1 interactions	PRR20C PRR20D PRR20B PRR20E PRR20A	2.33e-04	55	204	5	int:RIPPLY1
Cytoband	13q21.1	PRR20C PRR20D PRR20B PRR20E PRR20A	2.22e-09	13	207	5	13q21.1
Cytoband	4q22-q24	SLC39A8 CXXC4	6.05e-05	3	207	2	4q22-q24
Cytoband	Ensembl 112 genes in cytogenetic band chr13q21	PRR20C PRR20D PRR20B PRR20E PRR20A	1.98e-04	117	207	5	chr13q21
GeneFamily	Dishevelled segment polarity proteins\|PDZ domain containing	DVL1 DVL2 DVL3	1.58e-06	4	134	3	505
GeneFamily	EF-hand domain containing\|Spectrins	SPTA1 SPTBN5 SPTBN4	1.36e-05	7	134	3	1113
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN2A SCN8A	3.24e-05	9	134	3	1203
GeneFamily	Keratins, type I	KRT20 KRT14 KRT17 KRT28	5.14e-05	28	134	4	608
GeneFamily	Zinc fingers CXXC-type	KMT2B TET1 CXXC4	8.34e-05	12	134	3	136
GeneFamily	DNA helicases	RUVBL2 ASCC3 INO80	2.51e-04	17	134	3	1167
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	CYTH3 CYTH2 DNM1 PSD2 ASAP3 SPTBN4 AKAP13	8.72e-04	206	134	7	682
GeneFamily	Cyclic nucleotide gated channels	HCN2 HCN4	2.36e-03	10	134	2	250
GeneFamily	Immunoglobulin like domain containing	FCRL3 NECTIN2 CNTN1 CILP ICAM3 TEK	3.18e-03	193	134	6	594
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	SPAST INPP4A SPEG PTEN SSPOP TULP4 SCN1A CSAD SCN2A SCN8A KBTBD11 SYT1 DNM1 CNTN1 AKAP6 KRT14 PSD2 COL6A6 NTRK3 DGKE LAMC2 GRIP1 SH3PXD2A DACT3	4.63e-06	1106	201	24	M39071
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCN1A SCN2A SCN8A SYT1 DNM1 CNTN1 GRIP1 SPTBN4 MICAL2 PRKCE	2.85e-08	198	204	10	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B SPTA1 SSPOP GALNT13 FREM2 SCN2A CNTN1 FRAS1 APOB	1.87e-07	184	204	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B SPTA1 SSPOP GALNT13 FREM2 SCN2A CNTN1 FRAS1 APOB	1.87e-07	184	204	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B SPTA1 SSPOP GALNT13 FREM2 SCN2A CNTN1 FRAS1 APOB	1.87e-07	184	204	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP42 SPEG PGM5 ADK GLI1 SYT1 AKAP6 CACNB2 NTRK3	2.05e-07	186	204	9	6add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP42 SPEG PGM5 ADK FREM2 GLI1 SYT1 AKAP6 CACNB2	2.24e-07	188	204	9	293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT13 SCN1A SCN2A SCN8A SLC17A7 SYT1 DNM1 SPTBN4 PRKCE	2.35e-07	189	204	9	f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	CYTH3 GALNT13 DNM1 FLNC COMP CILP ADAMTS2 STXBP6 MICAL2	3.19e-07	196	204	9	24d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCN1A SCN2A SCN8A SYT1 DNM1 CNTN1 SPTBN4 MICAL2 PRKCE	3.48e-07	198	204	9	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCN1A SCN2A SCN8A SYT1 DNM1 CNTN1 SPTBN4 MICAL2 PRKCE	3.48e-07	198	204	9	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCN1A SCN2A SCN8A SYT1 DNM1 CNTN1 SPTBN4 MICAL2 PRKCE	3.48e-07	198	204	9	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARHGAP42 SPEG GLI1 FLNC CACNB2 ECE1 UBE2T CXXC4	6.06e-07	155	204	8	cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NOL6 QRICH2 SCN2A C3 ALOX15 AKAP6 FA2H TRIM71	8.86e-07	163	204	8	360cd65decda24853124f33a174f5224d7f3ce23
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NOL6 QRICH2 SCN2A C3 ALOX15 AKAP6 FA2H TRIM71	8.86e-07	163	204	8	b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PGM5 C16orf89 PAN2 VWF ECE1 TEK STXBP6 CXXC4	1.16e-06	169	204	8	04c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PGM5 C16orf89 PAN2 VWF ECE1 TEK STXBP6 CXXC4	1.16e-06	169	204	8	58136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAA1 MYO7B KBTBD11 KRT20 ARHGEF5 FA2H GPT APOB	1.27e-06	171	204	8	5d0d6c1ff610a703ae0b834a12823c5ff9012932
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAA1 MYO7B KBTBD11 KRT20 ARHGEF5 FA2H GPT APOB	1.58e-06	176	204	8	7622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN1A SCN2A SCN8A SLC17A7 SYT1 DNM1 SPTBN4 PRKCE	2.38e-06	186	204	8	7278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SLC39A8 C16orf89 FREM2 VWF COL6A6 TEK CREB3L4	2.47e-06	131	204	7	d5bc40cd585582856881081b7130dec3515b4ae0
ToppCell	droplet-Heart-HEART-1m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGM5 NECTIN2 FLNC VWF COMP ECE1 STXBP6 MICAL2	2.90e-06	191	204	8	4bfdf44d4402a42530d30c89d94946acdda4321b
ToppCell	droplet-Heart-nan-18m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC39A8 PGM5 NECTIN2 VWF COMP ECE1 TEK CXXC4	3.02e-06	192	204	8	0b9b2eaed45456d7d74ce78a64ef4a26ac2458fb
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN1A SCN2A SCN8A SLC17A7 SYT1 DNM1 SPTBN4 PRKCE	3.13e-06	193	204	8	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN1A SCN2A SCN8A SLC17A7 SYT1 DNM1 SPTBN4 PRKCE	3.13e-06	193	204	8	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	droplet-Heart-HEART-1m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGM5 SCN1A NECTIN2 FLNC VWF COMP STXBP6 MICAL2	3.13e-06	193	204	8	d0a5f212f8e8a13dbbe3e41df92548ef82eef70b
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN1A SCN2A SCN8A SLC17A7 SYT1 DNM1 SPTBN4 PRKCE	3.13e-06	193	204	8	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCN2A SCN8A SYT1 DNM1 CNTN1 SPTBN4 MICAL2 PRKCE	3.51e-06	196	204	8	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	droplet-Heart-nan-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC39A8 PGM5 NECTIN2 VWF COMP ECE1 TEK CXXC4	3.51e-06	196	204	8	e386526332138e636aef2542c11316347a45689c
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGM5 NECTIN2 VWF COMP ECE1 TEK STXBP6 MICAL2	3.51e-06	196	204	8	dbf154b3d166ffd07be717dac8d8a3350ac63e16
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGM5 NECTIN2 VWF COMP ECE1 TEK STXBP6 MICAL2	3.51e-06	196	204	8	7d5eaed189aa6116f3799be010139fb675ec65e0
ToppCell	Severe-B_intermediate-6\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TET2 DUS2 FCRL3 NLRC5 SYT1 ARL6IP5 TLN1 AKAP13	3.79e-06	198	204	8	8402421dc060926e968efe39a4e907f1e8ae5b1f
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	SCN2A SCN8A SYT1 DNM1 CNTN1 SPTBN4 MICAL2 PRKCE	4.08e-06	200	204	8	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ARHGAP42 PGM5 ADK GLI1 SYT1 CPLANE1 AKAP6 NTRK3	4.08e-06	200	204	8	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PGM5 SCN1A NECTIN2 FLNC COMP ECE1 KIAA1671	9.61e-06	161	204	7	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PGM5 SCN1A NECTIN2 FLNC COMP ECE1 KIAA1671	9.61e-06	161	204	7	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PGM5 SCN1A NECTIN2 FLNC COMP ECE1 KIAA1671	9.61e-06	161	204	7	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC39A8 C16orf89 C3 FRAS1 KRT14 COL6A6 GRIP1	1.22e-05	167	204	7	c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC39A8 C16orf89 C3 FRAS1 KRT14 COL6A6 GRIP1	1.22e-05	167	204	7	351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCell	facs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGRMC1 NECTIN2 VWF COMP ECE1 TEK CXXC4	1.59e-05	174	204	7	42dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCell	facs-Heart-RA-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGRMC1 NECTIN2 VWF COMP ECE1 TEK CXXC4	1.59e-05	174	204	7	f04edf2ca6788875c9918611e416fb739924382e
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACAA1 NOL6 ALOX15 TBXAS1 DMXL2 UBE2T USO1	1.78e-05	177	204	7	1d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FREM2 KRT20 C3 FLNC FRAS1 KRT14 COL6A6	1.84e-05	178	204	7	bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SLC39A8 C16orf89 FREM2 C3 FRAS1 KRT14 GRIP1	1.84e-05	178	204	7	1e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FREM2 KRT20 C3 FLNC FRAS1 KRT14 COL6A6	1.84e-05	178	204	7	c413861148129be1ee94f2ceb5999840217eebe5
ToppCell	facs\|World / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 KMT2B INPP4A KRT14 KRT17 DVL3 ECE1	1.91e-05	179	204	7	8001db3044e8657980e24422377c4fdb0d7b323e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN1A SCN2A SEL1L3 SLC17A7 SYT1 DNM1 KRT17	1.98e-05	180	204	7	f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 SLC39A8 PGM5 VWF COMP ECE1 CXXC4	2.20e-05	183	204	7	b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCell	VE-CD4-CD8_1\|VE / Condition, Cell_class and T cell subcluster	BCL2L14 SMUG1 LRRC47 AMOTL1 DACT3 AKAP13	2.21e-05	123	204	6	bc0f509716bb71d6e3fa343f4920ecb80eb62794
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	ACACB ST3GAL6 HOOK2 AKAP6 FLNC CACNB2 AKAP13	2.28e-05	184	204	7	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADM2 SCN1A SCN2A SCN8A SLC17A7 SYT1 DNM1	2.28e-05	184	204	7	7d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCell	droplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGM5 NECTIN2 KBTBD11 COMP GNB1L CREB3L4 PRKCE	2.36e-05	185	204	7	6a85399cfdb9b89683c874e7f046957f9a601dc2
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP42 SPEG PGM5 ADK SYT1 CACNB2 NTRK3	2.36e-05	185	204	7	e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCell	droplet-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGM5 NECTIN2 KBTBD11 COMP GNB1L CREB3L4 PRKCE	2.36e-05	185	204	7	64791056cdbb739136dbef08f4b16e2b5427faad
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARHGAP42 SPEG AMOTL1 FLNC CYP27C1 ECE1 MICAL2	2.36e-05	185	204	7	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP42 SPEG PGM5 ADK GLI1 SYT1 CACNB2	2.62e-05	188	204	7	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BCL2L14 GALNT13 C3 HOOK2 LAMC2 AKAP13	2.65e-05	127	204	6	5b0adbcafad31a6759c9bdce2f7f9591a8edc450
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 SLC39A8 PGM5 VWF COMP TEK STXBP6	2.71e-05	189	204	7	8e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 SLC39A8 PGM5 VWF COMP TEK STXBP6	2.71e-05	189	204	7	fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCell	droplet-Heart-nan-24m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC16 PGM5 VWF COMP ECE1 TEK CXXC4	2.71e-05	189	204	7	1137583e21d874c201c20581ba1995e2bfa3de59
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TET2 CYP1B1 GLT1D1 PTEN DMXL2 ADAMTS2 AKAP13	2.71e-05	189	204	7	55aba1ebc012006a5db3ff9c92589cb3d9f7c68a
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGM5 CSAD VWF COMP ECE1 TEK STXBP6	2.80e-05	190	204	7	6f71a9f74af7cd9a674753cfc9833ebe5bba0fa2
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CYP1B1 PGM5 C16orf89 VWF ECE1 TEK STXBP6	2.80e-05	190	204	7	e1b721bb74561fe51c53328a0394c9954e489049
ToppCell	droplet-Heart-nan-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC16 PGM5 VWF COMP ECE1 TEK CXXC4	2.80e-05	190	204	7	7068754c29f63a331e2b6c54715f3b26f37ad32b
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SCN2A SCN8A SYT1 DNM1 GRIP1 SPTBN4 PRKCE	2.80e-05	190	204	7	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPEG GALNT13 PGM5 AKAP6 CACNB2 MICAL2 DACT3	2.80e-05	190	204	7	562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	SP100 GALNT13 PGM5 HSPA6 CNTN1 STXBP6 L3MBTL4	2.80e-05	190	204	7	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPEG GALNT13 PGM5 AKAP6 CACNB2 MICAL2 DACT3	2.80e-05	190	204	7	f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP42 SPEG AKAP6 CACNB2 CILP NTRK3 DACT3	2.80e-05	190	204	7	73d94fbae92029745989a8712eed8b99fd84c193
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 C3 DNM1 ALOX15 FLNC FRAS1 ADAMTS2	2.89e-05	191	204	7	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	facs-Heart-RV-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGRMC1 MAP3K1 PGM5 VWF COMP ECE1 STXBP6	2.89e-05	191	204	7	f0c649bb32732c9dd38a0af8ce94d2a4d16de39a
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYP1B1 ARMCX4 PGM5 VWF ECE1 TEK STXBP6	2.89e-05	191	204	7	b270c3dd5952f56b9bdceabe13e298fe6757563b
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYP1B1 ARMCX4 PGM5 VWF ECE1 TEK STXBP6	2.89e-05	191	204	7	27f23c2254b610abac1a88d0fecff305addde9da
ToppCell	facs-Heart-RV-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGRMC1 MAP3K1 PGM5 VWF COMP ECE1 STXBP6	2.89e-05	191	204	7	e518c598719119e60c76016c586b1520c258bbcb
ToppCell	droplet-Lung-nan-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARMCX4 C16orf89 ADK VWF KRT28 ECE1 TEK	2.99e-05	192	204	7	45929c757d873fe314cc36d27abd265414635490
ToppCell	droplet-Lung-nan-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARMCX4 C16orf89 ADK VWF KRT28 ECE1 TEK	2.99e-05	192	204	7	beb336d3479821bdab7e8e2c58812f155e44e9a2
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C16orf89 ST3GAL6 VWF COMP ECE1 TEK SBNO2	2.99e-05	192	204	7	945153c41dde6e90d103206955e1707b54eb0665
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP42 SPEG ADK SYT1 CACNB2 NTRK3 DACT3	2.99e-05	192	204	7	992d08092edbc68c47b945deb8708379738c239a
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C16orf89 ST3GAL6 VWF COMP ECE1 TEK SBNO2	2.99e-05	192	204	7	6ab50579c63f31ca2cd41063a99b129f11c07510
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN1A SCN2A SCN8A SLC17A7 SYT1 DNM1 PRKCE	3.09e-05	193	204	7	5fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPEG PGM5 AKAP6 CACNB2 NTRK3 MICAL2 DACT3	3.20e-05	194	204	7	5c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	ACACB PGM5 AKAP6 CACNB2 FRAS1 GRIP1 L3MBTL4	3.20e-05	194	204	7	c3535f7cc0076653c72db582047cff053c322397
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPEG PGM5 AKAP6 CACNB2 NTRK3 MICAL2 DACT3	3.20e-05	194	204	7	ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC39A8 PGM5 VWF COMP ECE1 TEK STXBP6	3.20e-05	194	204	7	c5e77650d7abee339ec38fa78a622bb124db3fa5
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	EPPK1 C16orf89 FREM2 SEL1L3 KRT17 LAMC2 MICAL2	3.30e-05	195	204	7	62d369a8af2b76a2553bc8ff9cb89a133b060123
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C16orf89 ST3GAL6 VWF COMP ECE1 TEK SBNO2	3.30e-05	195	204	7	4db30b3bc65c25626f828cd4f867f20c71809898
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC39A8 PGM5 VWF COMP ECE1 TEK STXBP6	3.30e-05	195	204	7	df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCN1A SCN2A SLC17A7 CUX2 TRIM54 MICAL2 RORB	3.30e-05	195	204	7	787e95fb59c40bba784544b662fac37606ae1427
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC39A8 C16orf89 FREM2 SCN1A C3 NPC1 AKAP13	3.41e-05	196	204	7	7e5addaa844e66f8160e05858c341866a80aed23
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC39A8 C16orf89 FREM2 SCN1A C3 NPC1 AKAP13	3.52e-05	197	204	7	bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPEG CNTN1 KRT14 PSD2 KRT17 NTRK3 LAMC2	3.52e-05	197	204	7	f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	TET2 SP100 DYNC1H1 DMXL2 TLN1 AKAP13 MX1	3.64e-05	198	204	7	61ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPEG PGM5 CNTN1 AKAP6 FLNC CACNB2 DACT3	3.64e-05	198	204	7	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCN2A SCN8A SYT1 DNM1 CNTN1 GRIP1 SPTBN4	3.64e-05	198	204	7	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SLC39A8 C16orf89 FREM2 SCN1A C3 MICAL2 PALM3	3.76e-05	199	204	7	a38a981cffa61c8444a980916de7414e689a1b63
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC39A8 C16orf89 FREM2 SCN1A C3 NPC1 AKAP13	3.76e-05	199	204	7	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal-Mesoderm\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	ACACB GLT1D1 SEL1L3 RAD23B CYP27C1 ALPK1 PRKCE	3.88e-05	200	204	7	0f4b8b0868bda406fe6bf01d1b722510fdfd0168
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar-AT2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SLC39A8 C16orf89 FREM2 SCN1A C3 MICAL2 PALM3	3.88e-05	200	204	7	b535323e18d9fb0dde1e0026df142c831e48c29f
ToppCell	Biopsy_Control_(H.)-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	DNM1 FLNC COL6A6 CILP TRIM54 TET1 HHIPL1	3.88e-05	200	204	7	cdaf462b1db29dab61038eeab5ddd3eef3386763
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B SSPOP SCN8A PSD2 GRIP1 CPLX3	4.05e-05	137	204	6	4dcb15de821439011df1bb0bbd7682d674bd725d
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B SSPOP SCN8A PSD2 GRIP1 CPLX3	4.05e-05	137	204	6	c05ceeb7b483324604cb3f647d2da2b3786071b1
Drug	Demecarium bromide [56-94-0]; Up 200; 5.6uM; MCF7; HT_HG-U133A	SP1 ACACB INPP4A SPEG SPTBN5 NF1 KBTBD11 CNTN1 HCN4 ASAP3 MLXIP CARF CXXC4	2.07e-08	197	199	13	2773_UP
Drug	factor IIIm	GFPT1 GLI1 CNTN1 LAMC2	3.86e-07	8	199	4	CID006323227
Drug	cycloprodigiosin	MAP3K1 SYT1 GPT2 GPT IKBKB	1.44e-06	23	199	5	CID006439795
Drug	Conessine [546-06-5]; Up 200; 11.2uM; MCF7; HT_HG-U133A	RALGAPA1 ACACB SPEG SPTA1 NF1 ALOX15 CNTN1 DVL2 ASAP3 LAMC2 STS	1.51e-06	199	199	11	4777_UP
Drug	2-nitro-5-thiocyanobenzoic acid	ACAA1 SPTA1 GFPT1 SPTBN5 CNDP1 SPTBN4	3.74e-06	48	199	6	CID000092266
Drug	dimethyl adipimidate	SPTA1 SPTBN5 SCN2A SPTBN4 NNT	5.79e-06	30	199	5	CID000025738
Drug	proadifen hydrochloride	CYP1B1 CYP2D7 GPT2 ALOX15 FA2H GPT MIB2 USO1	7.38e-06	114	199	8	CID000004910
Drug	Progesterone [57-83-0]; Down 200; 12.8uM; PC3; HT_HG-U133A	CYP1B1 SP100 ACACB DUS2 NF1 KBTBD11 SYT1 ECE1 ARNT NNT	8.10e-06	193	199	10	6646_DN
Drug	Pancuronium bromide [15500-66-0]; Down 200; 5.4uM; MCF7; HT_HG-U133A	SP1 MAP3K1 NF1 ALOX15 DMXL2 ASAP3 ARNT STS NUP188 IKBKB	8.87e-06	195	199	10	4393_DN
Drug	Methoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; PC3; HT_HG-U133A	CYP1B1 ACACB NF1 C3 CPLANE1 DVL2 ASAP3 STS NNT MX1	8.87e-06	195	199	10	6661_DN
Drug	Pentetic acid [67-43-6]; Up 200; 10.2uM; MCF7; HT_HG-U133A	SPTBN5 NF1 CACNB2 FRAS1 GPT DGKE ECE1 STS CARF CXXC4	9.27e-06	196	199	10	3387_UP
Drug	Scopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; PC3; HT_HG-U133A	INPP4A DUS2 DDX54 PAN2 SYT1 RAD23B RNF31 GNB1L NNT MX1	9.27e-06	196	199	10	2099_DN
Drug	Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A	ACACB NF1 ALOX15 DMXL2 ASAP3 DVL3 ALPK1 ECE1 CXXC4 PRKCE	9.70e-06	197	199	10	3351_UP
Drug	CP-690334-01 [459212-38-5]; Down 200; 1uM; PC3; HT_HG-U133A	SPEG DDX54 C3 RNF31 ASAP3 DGKE LAMC2 ARNT AKAP13 IKBKB	1.06e-05	199	199	10	4561_DN
Drug	Flunixin meglumine [42461-84-7]; Down 200; 8.2uM; PC3; HT_HG-U133A	EPHB3 DUS2 NF1 C3 CPLANE1 CACNB2 DVL2 DGKE IKBKB MX1	1.11e-05	200	199	10	3713_DN
Drug	bifendate	GPT2 GPT APOB	3.57e-05	8	199	3	CID000108213
Drug	Androgen Antagonists	NF1 SLC17A7 CACNB2 NTRK3 GRIP1 STS	5.04e-05	75	199	6	ctd:D000726
Drug	Prochlorperazine dimaleate [84-02-6]; Down 200; 6.6uM; PC3; HT_HG-U133A	SP100 KMT2B SMUG1 INPP4A NF1 DVL2 LAMC2 ARNT AKAP13	5.07e-05	192	199	9	6664_DN
Drug	AC1L9K72	ACAA1 SPTA1 SPTBN5 UBA1 ALOX15 CNTN1 NPC1 PSD2 DGKE APOB SPTBN4	5.23e-05	290	199	11	CID000446872
Drug	N-benzylformamide	CYP1B1 CYP2D7 CYP11A1 GPT2 PHIP GPT	5.44e-05	76	199	6	CID000080654
Drug	Cyproterone acetate [427-51-0]; Down 200; 9.6uM; PC3; HT_HG-U133A	RALGAPA1 CYP1B1 NECTIN2 DDX54 PAN2 SYT1 ASAP3 STS MX1	5.49e-05	194	199	9	4470_DN
Drug	Fluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; PC3; HT_HG-U133A	INPP4A MAP3K1 SCN1A ARNT MICAL2 TLN1 CARF PRKCE NNT	5.72e-05	195	199	9	6691_UP
Drug	Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; MCF7; HT_HG-U133A	ACACB INPP4A SPTBN5 ALOX15 ASAP3 SPTBN4 STS STXBP6 TLN1	6.19e-05	197	199	9	2305_UP
Drug	Etofenamate [30544-47-9]; Down 200; 10.8uM; PC3; HT_HG-U133A	CYP1B1 INPP4A SYT1 CPLANE1 ALPK1 ECE1 PIGZ STS MX1	6.19e-05	197	199	9	3989_DN
Drug	Fluoxetine hydrochloride [59333-67-4]; Down 200; 11.6uM; MCF7; HT_HG-U133A	SP100 INPP4A DUS2 NF1 LAMC2 ALPK1 ECE1 SBNO2 TLN1	6.19e-05	197	199	9	3314_DN
Drug	Clopamide [636-54-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A	SP1 INPP4A C3 ALOX15 MLXIP ARNT PRKCE NUP188 IKBKB	6.19e-05	197	199	9	5402_UP
Drug	cholesterol sulfate	CYP11A1 C3 NPC1 VWF LAMC2 STS PRKCE	6.20e-05	113	199	7	CID000065076
Drug	Gg-O	SMUG1 PGRMC1 MAP3K1 DYNC1H1	6.20e-05	25	199	4	CID016040279
Drug	Aztreonam [78110-38-0]; Up 200; 9.2uM; PC3; HT_HG-U133A	SP100 INPP4A NF1 ST3GAL6 KBTBD11 DGKE ALPK1 STS TLN1	6.43e-05	198	199	9	2118_UP
Drug	sulindac; Down 200; 50uM; MCF7; HG-U133A	ADM2 SPTBN5 DUS2 NF1 RAD23B NTRK3 GNB1L TLN1 PRKCE	6.43e-05	198	199	9	307_DN
Drug	Reserpinic acid hydrochloride; Up 200; 9.2uM; PC3; HT_HG-U133A	ACACB INPP4A NF1 C3 CACNB2 CILP DVL2 ASAP3 DGKE	6.43e-05	198	199	9	6603_UP
Drug	wortmannin; Down 200; 0.01uM; ssMCF7; HG-U133A	EPHB3 KMT2B INPP4A ADM2 NF1 ECE1 SBNO2 ARNT MX1	6.69e-05	199	199	9	404_DN
Drug	Torsemide [56211-40-6]; Up 200; 11.4uM; HL60; HT_HG-U133A	ACACB INPP4A MAP3K1 SLC17A7 MLXIP TRIM45 STXBP6 PRKCE NUP188	6.69e-05	199	199	9	2956_UP
Drug	Piracetam [7491-74-9]; Down 200; 28.2uM; PC3; HT_HG-U133A	CYP1B1 SCN8A RNF31 FA2H CANX ARNT STS PRKCE NNT	6.95e-05	200	199	9	5043_DN
Drug	Oxamniquine [21738-42-1]; Up 200; 14.4uM; PC3; HT_HG-U133A	INPP4A CYTH3 SPICE1 CNTN1 ASAP3 LAMC2 ECE1 STS CARF	6.95e-05	200	199	9	4006_UP
Drug	irisolidone	SP1 GPT2 GPT	7.54e-05	10	199	3	CID005281781
Drug	4-tert-butylthiazole	GPT2 GPT	7.60e-05	2	199	2	CID000581111
Drug	cetefloxacin	GPT2 GPT	7.60e-05	2	199	2	CID000065995
Drug	L-645,164	GPT2 GPT	7.60e-05	2	199	2	CID006439709
Drug	paeonoside	GPT2 GPT	7.60e-05	2	199	2	CID000442924
Drug	S00305	GPT2 GPT	7.60e-05	2	199	2	CID006419754
Drug	2-phenylthiazole	GPT2 GPT	7.60e-05	2	199	2	CID000547494
Drug	Anti-Bacterial Agents	PTEN GPT	7.60e-05	2	199	2	ctd:D000900
Drug	1-fluorohexane	GPT2 GPT	7.60e-05	2	199	2	CID000009760
Drug	Apiopeonoside	GPT2 GPT	7.60e-05	2	199	2	CID000127509
Drug	SPM VIII	NPC1 MX1	7.60e-05	2	199	2	CID000188408
Drug	4-chlorobenzothioamide	GPT2 GPT	7.60e-05	2	199	2	CID002734826
Drug	p-methoxythiobenzamide	GPT2 GPT	7.60e-05	2	199	2	CID000736827
Drug	deoxoviroidin	GPT2 GPT	7.60e-05	2	199	2	CID000156810
Drug	deoxoviroisin	GPT2 GPT	7.60e-05	2	199	2	CID000156812
Drug	dichloralurea	ACAA1 C3 DNM1 NNT	8.49e-05	27	199	4	CID000008313
Drug	dipyridamole	ACAA1 PGRMC1 ADK CNTN1 TBXAS1 VWF STS TET1	9.26e-05	162	199	8	CID000003108
Drug	AC1O0B8G	CYP1B1 MAP3K1 HSPA6 ALOX15 TBXAS1 KRT14 KRT17 LAMC2 IKBKB MX1	1.09e-04	262	199	10	CID000091605
Drug	AC1N9TEG	CYTH3 CYTH2 PTEN NF1 SYT1 INO80 STS	1.11e-04	124	199	7	CID000000478
Disease	Profound Mental Retardation	INPP4A PTEN ADK NF1 SCN1A SCN8A ASCC3 PHIP DYNC1H1 CNDP1	3.06e-08	139	194	10	C0020796
Disease	Mental deficiency	INPP4A PTEN ADK NF1 SCN1A SCN8A ASCC3 PHIP DYNC1H1 CNDP1	3.06e-08	139	194	10	C0917816
Disease	Mental Retardation, Psychosocial	INPP4A PTEN ADK NF1 SCN1A SCN8A ASCC3 PHIP DYNC1H1 CNDP1	3.06e-08	139	194	10	C0025363
Disease	obsolete aging, cognition	PRR20C PRR20D PRR20B PRR20E PRR20A	3.32e-08	15	194	5	EFO_0003925, GO_0007568
Disease	Intellectual Disability	RALGAPA1 ZNF142 INPP4A PTEN ADK NF1 SCN1A SCN8A SYT1 ASCC3 GPT2 PHIP DYNC1H1 CNDP1 AKAP6 CUX2	5.12e-08	447	194	16	C3714756
Disease	Cryptophthalmos syndrome	FREM2 FRAS1 GRIP1	2.80e-07	3	194	3	C0265233
Disease	FRASER SYNDROME 1	FREM2 FRAS1 GRIP1	2.80e-07	3	194	3	C4551480
Disease	Fraser syndrome (implicated_via_orthology)	FREM2 FRAS1 GRIP1	1.11e-06	4	194	3	DOID:0090001 (implicated_via_orthology)
Disease	t-tau:beta-amyloid 1-42 ratio measurement	BCL2L14 PRR20C PRR20D PRR20B PRR20E PRR20A	4.89e-06	66	194	6	EFO_0007708
Disease	Lennox-Gastaut syndrome	SCN1A DNM1 CUX2	5.52e-06	6	194	3	C0238111
Disease	Colorectal Carcinoma	TET2 CYP1B1 PTEN LRRC47 NF1 PAN2 KRT20 PHIP CNTN1 AKAP6 FLNC CACNB2 ASAP3 APOB ARNT PRKCE	1.80e-05	702	194	16	C0009402
Disease	Dystonia	ZNF142 KMT2B PTEN AFG3L2 FOXRED1 FA2H	2.27e-05	86	194	6	C0013421
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN2A SCN8A	3.25e-05	10	194	3	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN2A SCN8A	3.25e-05	10	194	3	DOID:0080422 (implicated_via_orthology)
Disease	Neurodevelopmental Disorders	SPAST PTEN SCN1A SCN2A SCN8A DNM1	3.54e-05	93	194	6	C1535926
Disease	neurodegenerative disease (implicated_via_orthology)	DVL1P1 AFG3L2 SLC17A7 DYNC1H1 DVL1 DVL2 DVL3	5.12e-05	145	194	7	DOID:1289 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN2A SCN8A	5.89e-05	12	194	3	DOID:0060170 (implicated_via_orthology)
Disease	Benign familial infantile epilepsy	SCN2A SCN8A	1.28e-04	3	194	2	cv:C5575231
Disease	Fibrosarcoma	NF1 NTRK3	1.28e-04	3	194	2	C0016057
Disease	GLAUCOMA 3, PRIMARY INFANTILE, B	CYP1B1 TEK	1.28e-04	3	194	2	600975
Disease	GLAUCOMA 3, PRIMARY INFANTILE, B	CYP1B1 TEK	1.28e-04	3	194	2	C1832977
Disease	Glaucoma 3, primary infantile, B	CYP1B1 TEK	1.28e-04	3	194	2	cv:C1832977
Disease	Early infantile epileptic encephalopathy with suppression bursts	SCN1A SCN2A DNM1	1.47e-04	16	194	3	C0393706
Disease	hereditary spastic paraplegia (implicated_via_orthology)	SPAST AFG3L2 DNM1 MX1	1.83e-04	43	194	4	DOID:2476 (implicated_via_orthology)
Disease	mosaic loss of chromosome Y measurement	PRR20C PRR20D PRR20B PRR20E PRR20A	1.88e-04	80	194	5	EFO_0007783
Disease	Malignant neoplasm of prostate	TET2 CYP1B1 PTEN PGRMC1 MAP3K1 NECTIN2 RAD23B TBXAS1 RNF31 ARHGEF5 CREB3L4 USO1 AKAP13	2.37e-04	616	194	13	C0376358
Disease	Prostatic Neoplasms	TET2 CYP1B1 PTEN PGRMC1 MAP3K1 NECTIN2 RAD23B TBXAS1 RNF31 ARHGEF5 CREB3L4 USO1 AKAP13	2.37e-04	616	194	13	C0033578
Disease	telomere length	PRR20C PRR20D PRR20B PRR20E CPLANE1 ADAMTS2 PRR20A SH3PXD2A MICAL2	2.43e-04	313	194	9	EFO_0004505
Disease	Robinow Syndrome	DVL1 DVL3	2.56e-04	4	194	2	C0265205
Disease	Robinow Syndrome, Autosomal Dominant	DVL1 DVL3	2.56e-04	4	194	2	C4551476
Disease	Malignant Peripheral Nerve Sheath Tumor	NF1 SH3PXD2A	2.56e-04	4	194	2	C0751690
Disease	Malignant neoplasm of breast	CYP1B1 SPAST PTEN MAP3K1 FCRL3 NF1 GLI1 NECTIN2 NLRC5 AKAP6 TBXAS1 KRT14 VWF GNB1L DVL3 DGKE TEK IKBKB	2.77e-04	1074	194	18	C0006142
Disease	Fatty Liver	CYP1B1 PTEN GPT APOB STS	2.94e-04	88	194	5	C0015695
Disease	Steatohepatitis	CYP1B1 PTEN GPT APOB STS	2.94e-04	88	194	5	C2711227
Disease	coronary artery disease	ARHGAP42 TET2 CYP1B1 SMUG1 GALNT13 MAP3K1 PAN2 NPC1 TBXAS1 CUX2 HCN4 APOB INO80 TEK RSBN1 CARF PRKCE AKAP13 HHIPL1	3.57e-04	1194	194	19	EFO_0001645
Disease	lung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma	TET2 DVL1P1 MAP3K1 DVL1	3.83e-04	52	194	4	EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575
Disease	centronuclear myopathy 1 (implicated_via_orthology)	DNM1 MX1	4.24e-04	5	194	2	DOID:0111223 (implicated_via_orthology)
Disease	microcytic anemia (implicated_via_orthology)	DNM1 MX1	4.24e-04	5	194	2	DOID:11252 (implicated_via_orthology)
Disease	gestational blood glucose measurement	MAP3K1 PRKCE	4.24e-04	5	194	2	EFO_0009698
Disease	Hydrophthalmos	CYP1B1 TEK	4.24e-04	5	194	2	C0020302
Disease	Charcot-Marie-Tooth disease dominant intermediate B (implicated_via_orthology)	DNM1 MX1	4.24e-04	5	194	2	DOID:0110197 (implicated_via_orthology)
Disease	DiGeorge syndrome (is_implicated_in)	DVL1P1 DVL1	4.24e-04	5	194	2	DOID:11198 (is_implicated_in)
Disease	Tinnitus, wellbeing measurement	PRR20C PRR20D PRR20B PRR20E PRR20A	4.39e-04	96	194	5	EFO_0007869, HP_0000360
Disease	FEV/FEC ratio	ARHGAP42 TET2 CYP1B1 SPEG MAP3K1 ADK SPTBN5 FREM2 RAD23B AKAP6 FRAS1 ADAMTS2 GNB1L LAMC2 C5orf47 USP8 SH3PXD2A PRKCE HHIPL1	5.03e-04	1228	194	19	EFO_0004713
Disease	apolipoprotein A 1 measurement	TET2 SP1 SPAST ACACB AKR1C4 SLC39A8 DUS2 GLI1 NECTIN2 NLRC5 PHIP NPC1 APOB MLXIP NNT	5.20e-04	848	194	15	EFO_0004614
Disease	Disorder of eye	CYP1B1 FREM2 C1QTNF5 CPLANE1 FRAS1 GRIP1 MFSD8	5.30e-04	212	194	7	C0015397
Disease	EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 1	SCN1A DNM1	6.34e-04	6	194	2	C3463992
Disease	familial combined hyperlipidemia (is_marker_for)	VWF APOB	6.34e-04	6	194	2	DOID:13809 (is_marker_for)
Disease	Familial benign neonatal epilepsy	SCN2A SCN8A	6.34e-04	6	194	2	C0220669
Disease	clubfoot (implicated_via_orthology)	FRAS1 GRIP1	6.34e-04	6	194	2	DOID:11836 (implicated_via_orthology)
Disease	Insulin Sensitivity	ACACB PTEN C3 STS	6.63e-04	60	194	4	C0920563
Disease	Insulin Resistance	ACACB PTEN C3 STS	6.63e-04	60	194	4	C0021655
Disease	cholesterol to total lipids in medium HDL percentage	SLC39A8 NECTIN2 NLRC5 APOB	6.63e-04	60	194	4	EFO_0022237
Disease	serum alanine aminotransferase measurement	PTEN SLC39A8 GALNT13 MAP3K1 NECTIN2 HSPA6 NPC1 CUX2 GPT DVL2 DNAH2 APOB MLXIP TET1 MX1	6.68e-04	869	194	15	EFO_0004735
Disease	uric acid measurement	TET2 DCDC1 QRICH2 SLC39A8 DUS2 TMEM174 SYT1 FRAS1 CUX2 ARL6IP5 MLXIP AKAP13	7.61e-04	610	194	12	EFO_0004761
Disease	atrial fibrillation	SYNPO2L SLC39A8 AKAP6 CUX2 HCN4 ALPK1 C5orf47 KLHL38 SH3PXD2A	8.27e-04	371	194	9	EFO_0000275
Disease	Seizure, Febrile, Complex	SCN1A SCN2A	8.84e-04	7	194	2	C0751057
Disease	Seizure, Febrile, Simple	SCN1A SCN2A	8.84e-04	7	194	2	C0149886
Disease	Leukemia, Myelocytic, Acute	TET2 NF1 NECTIN2 NTRK3 UBE2T MX1	1.03e-03	173	194	6	C0023467
Disease	Polydactyly	PTEN FREM2 CPLANE1 FRAS1 GRIP1	1.08e-03	117	194	5	C0152427
Disease	fatty liver disease (implicated_via_orthology)	ACACB PTEN ADK	1.10e-03	31	194	3	DOID:9452 (implicated_via_orthology)
Disease	white matter microstructure measurement	EPPK1 KMT2B DCDC1 SLC39A8 CACNB2 APOB ECE1 SH3PXD2A CARF	1.17e-03	390	194	9	EFO_0005674
Disease	X-linked infantile spasms	SCN1A DNM1	1.17e-03	8	194	2	C4552072
Disease	Unilateral agenesis of kidney	FREM2 FRAS1	1.17e-03	8	194	2	C0266294
Disease	Brugada syndrome	CACNB2 HCN4	1.17e-03	8	194	2	cv:C1142166
Disease	monocyte count	ARHGAP42 RALGAPA1 TET2 SP100 SPTA1 SLC39A8 NF1 NLRC5 SYT1 C3 HOOK2 HSPA7 VARS1 TBXAS1 RSBN1 STXBP6 TLN1 PRKCE AKAP13	1.18e-03	1320	194	19	EFO_0005091
Disease	triglycerides to total lipids in small HDL percentage	SLC39A8 NECTIN2 NLRC5 APOB	1.31e-03	72	194	4	EFO_0022336
Disease	left ventricular mass index	SYNPO2L FLNC CACNB2	1.44e-03	34	194	3	EFO_0009290
Disease	heart failure	SYNPO2L SLC39A8 PHIP NPC1 FLNC CACNB2	1.45e-03	185	194	6	EFO_0003144
Disease	membranous glomerulonephritis (implicated_via_orthology)	C3 TBXAS1	1.50e-03	9	194	2	DOID:10976 (implicated_via_orthology)
Disease	Generalized Epilepsy with Febrile Seizures Plus	SCN1A SCN2A	1.50e-03	9	194	2	C3502809
Disease	Febrile Convulsions	SCN1A SCN2A	1.50e-03	9	194	2	C0009952
Disease	C3 glomerulopathy	C3 DGKE	1.50e-03	9	194	2	C4087273
Disease	2-hydroxystearate measurement	CNTN1 TEK	1.50e-03	9	194	2	EFO_0021059
Disease	liver cancer (is_marker_for)	GPT2 GPT	1.50e-03	9	194	2	DOID:3571 (is_marker_for)
Disease	diastolic blood pressure, systolic blood pressure	SP1 DCDC1 SPEG PTEN ADK ALOX15 CACNB2 HCN4 CANX DNAH2 KIAA1671 PRKCE	1.69e-03	670	194	12	EFO_0006335, EFO_0006336
Disease	cholesteryl esters to total lipids in very large HDL percentage	NECTIN2 NLRC5 APOB	1.70e-03	36	194	3	EFO_0022257
Disease	choline measurement	AKR1C4 SLC39A8 ASAP3 NSL1 APOB	1.72e-03	130	194	5	EFO_0010116
Disease	mean arterial pressure	ARHGAP42 DCDC1 SYNPO2L SLC39A8 PHIP CACNB2 CUX2 USP8 CPLX3 PRKCE	1.81e-03	499	194	10	EFO_0006340
Disease	cyclic AMP-responsive element-binding protein 3-like protein 4 measurement	CREB3L4 USP8	1.87e-03	10	194	2	EFO_0801506
Disease	Atypical Hemolytic Uremic Syndrome	C3 DGKE	1.87e-03	10	194	2	C2931788
Disease	coffee consumption measurement, insomnia	SLC39A8 KRT17	1.87e-03	10	194	2	EFO_0004698, EFO_0006781
Disease	Peripheral T-Cell Lymphoma	TET2 NECTIN2	1.87e-03	10	194	2	C0079774
Disease	pneumonia (implicated_via_orthology)	C3 IKBKB	1.87e-03	10	194	2	DOID:552 (implicated_via_orthology)
Disease	Epilepsy, Cryptogenic	SCN1A SCN2A SCN8A DNM1	2.12e-03	82	194	4	C0086237
Disease	Awakening Epilepsy	SCN1A SCN2A SCN8A DNM1	2.12e-03	82	194	4	C0751111
Disease	Aura	SCN1A SCN2A SCN8A DNM1	2.12e-03	82	194	4	C0236018
Disease	pulse pressure measurement	ARHGAP42 TET2 TTC16 SYNPO2L PTEN SSPOP SYT1 NPC1 TBXAS1 CACNB2 CUX2 INO80 SPTBN4 TET1 COMMD7 PRKCE AKAP13 HHIPL1 NNT	2.16e-03	1392	194	19	EFO_0005763
Disease	Other specified cardiac arrhythmias	CACNB2 HCN4	2.27e-03	11	194	2	C0348626
Disease	cocaine use	CYP11A1 SCN1A	2.27e-03	11	194	2	C3496069
Disease	Hemolytic-Uremic Syndrome	C3 DGKE	2.27e-03	11	194	2	C0019061
Disease	Nodal rhythm disorder	CACNB2 HCN4	2.27e-03	11	194	2	C0264893
Disease	Ectopic rhythm	CACNB2 HCN4	2.27e-03	11	194	2	C1399226
Disease	Tremor	ZNF142 SCN8A	2.27e-03	11	194	2	C0040822
Disease	brain infarction (implicated_via_orthology)	ADK TBXAS1	2.27e-03	11	194	2	DOID:3454 (implicated_via_orthology)
Disease	CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)	CACNB2 HCN4	2.27e-03	11	194	2	C2748542
Disease	lipoprotein measurement, phospholipid measurement	AKR1C4 SLC39A8 ASAP3 APOB	2.42e-03	85	194	4	EFO_0004639, EFO_0004732
Disease	Congenital small ears	FREM2 FRAS1 GRIP1	2.48e-03	41	194	3	C0152423
Disease	Nodular glomerulosclerosis	CNDP1 ALPK1 PRKCE	2.48e-03	41	194	3	C0017667
Disease	urate measurement	DCDC1 CCDC81 QRICH2 SLC39A8 TMEM174 GLI1 NECTIN2 SYT1 VARS1 CUX2 KRT17 ARL6IP5 MLXIP AKAP13	2.50e-03	895	194	14	EFO_0004531

Protein segments in the cluster

Peptide	Gene	Start	Entry
QRVELNDGHFMPVLG	AKR1C4	6	P17516
IRANIGDAQAMGQQP	GPT2	91	Q8TD30
ANIGDAQAMGQRPIT	GPT	66	P24298
LQAQRGAGLAPVMGQ	ADM2	66	Q7Z4H4
QQTELDMVPGRDGLA	ARNT	506	P27540
RPNIVLLMADDLGVG	ARSH	6	Q5FYA8
VIDGQNLMPLLEGRA	ARSH	401	Q5FYA8
TGGIPGEVAQDMQRE	ASAP3	171	Q8TDY4
EQRLPEINLDGMVGV	C16orf89	51	Q6UX73
DMVAQVLRAEGAAPQ	CYP27C1	126	Q4G0S4
EAPQALRENILFGMG	ADK	16	P55263
GQISFDLPRQGDMVL	AFG3L2	671	Q9Y4W6
EQEDMERKAQGQGGP	ARHGEF5	306	Q12774
QGREIVQTMNSDPGL	COMP	556	P49747
SGDAVLQRDLVMEPG	AKAP13	441	Q12802
VTGVNALQGMAEPRR	AKAP13	1091	Q12802
EQEDMERKAQGQGGP	ARHGEF35	306	A5YM69
DAPVIHQEMIGGLRN	C3	1121	P01024
DQVLMGVDPRGESEV	BCL2L14	251	Q9BZR8
GPDAFAIVERAQQMV	AMOTL1	431	Q8IY63
REVPLGAGQQESMEA	C8orf58	146	Q8NAV2
RNIGAGVMQIDIIQG	DMXL2	2991	Q8TDJ6
GLEEMQVEREGSLNP	CCDC180	736	Q9P1Z9
AQQQALLEMEVAPRG	CUX2	706	O14529
GRIEPGDMLLQVNEI	DVL3	291	Q92997
AADGRIEPGDMLLQV	DVL2	306	O14641
NPNVVLKAEVGEGAM	ARMCX4	651	Q5H9R4
GDEVRLGSIMAPLVQ	ADAMTS2	426	O95450
LEGAPEGIQEVRNMG	ALPK1	691	Q96QP1
IQMELLENVAPAGAL	CACNB2	21	Q08289
LMGIPGDRESQAVVD	RAD23B	226	P54727
PRGDLAQMEQSVGRL	QRICH2	1481	Q9H0J4
QVGNIPGRLVAEMEV	RIMBP3B	1506	A6NNM3
QVGNIPGRLVAEMEV	RIMBP3C	1506	A6NJZ7
VNGISIQEMPAAGRG	INO80	1411	Q9ULG1
DMLPVITGNRDGFNV	INPP4A	756	Q96PE3
MAGLRNESEQEPLLG	MFSD8	1	Q8NHS3
AEAMGEIGRVPEVVQ	PALM3	286	A6NDB9
IEIVVQMAAANGIGR	PGM5	76	Q15124
DSQGQLVEMNRLPGG	ACACB	1751	O00763
EQGEGFSQVLRMQPV	NSL1	196	Q96IY1
NEMPQIGDLVGLDAE	PAN2	966	Q504Q3
VQGPNLRSGMEVVLV	DCDC1	1186	M0R2J8
GNVNVEMNAAPGVDL	KRT28	241	Q7Z3Y7
PEGGMLQITNRILQA	FRAS1	1341	Q86XX4
SLPVVQNLGMRVQEG	FRAS1	2311	Q86XX4
AVPGRGSDEVQILEM	GNB1L	131	Q9BYB4
PDGMIVVVDFGNNRI	TRIM71	851	Q2Q1W2
LQAQGEAPGLMDVQI	MAGEA8	16	P43361
LDNRMPGLVGQEVGS	KIAA1671	106	Q9BY89
PNVVAARDVPEGMQN	IKBKB	71	O14920
AMILVDGQPRQAKGE	NTRK3	636	Q16288
LEEVANGLRNPVAMV	HHIPL1	186	Q96JK4
EMNALRGQVGGDVNV	KRT14	256	P02533
MGNRGMEDLIPLVNR	DNM1	1	Q05193
GMALQQRAGEERAPA	HOOK2	671	Q96ED9
LMSPGENGEVRQGQA	PRKCE	386	Q02156
IVGAVVRGMDLQPGN	LRRC47	336	Q8N1G4
GRVMVDPVQNLGDSF	FREM2	2896	Q5SZK8
PNRLVDNIDMIDGDG	BEX5	51	Q5H9J7
GIPFVNAGSRAVVME	CARF	271	Q8N187
VDGMLGRVPQSVVDE	DDX54	476	Q8TDD1
ITPQGVAMRAGVLAD	PDZK1P1	41	A8MUH7
FDGVQDPRILMAING	PGRMC1	81	O00264
GQNIERSPFEVNVGM	FLNC	356	Q14315
AGEQLRGATGEPEVM	NOL6	6	Q9H6R4
LGRRQPVMVAVGQHE	ALOX15	596	P16050
MGQFDHPNIIRLEGV	EPHB3	686	P54753
NIPGDVLRAVEQAMG	LRRC45	211	Q96CN5
ENGFQIGMRLEGIDP	L3MBTL4	81	Q8NA19
AAMDARGLQEEPEVG	GLI1	696	P08151
AVALGQARAMVPEDV	KMT2B	876	Q9UMN6
EVDAAPGLNLGVIMN	KRT20	226	P35900
LPEAEVRLGQAGFMQ	HCN4	201	Q9Y3Q4
MQAPRELAVGIDLGT	HSPA7	1	P48741
GDEAAAELAQVLPQM	NLRC5	1781	Q86WI3
RTELDMQPQGLGLFV	ICAM3	191	P32942
RQGAEGLMAPDVHIQ	PRR20D	101	P86480
LRAVISRNQEGPGEM	GALNT13	46	Q8IUC8
DQQLGRVLGEVAPSM	NPC1	721	O15118
RQGAEGLMAPDVHIQ	PRR20A	101	P86496
RQGAEGLMAPDVHIQ	PRR20B	101	P86481
RGEQQGSMENEPVAL	FA2H	86	Q7L5A8
REIAHLGNADMIQPG	MLXIP	301	Q9HAP2
QIQMAGGDVELPREL	CPLX3	91	Q8WVH0
NMGIIIPDFARSGVQ	APOB	886	P04114
QEKPREAMAVAGVQG	C5orf47	51	Q569G3
AMRGLGELGAQPQQD	GLP2R	506	O95838
MNALRGQVGGEINVE	KRT17	226	Q04695
GQVGGEINVEMDAAP	KRT17	231	Q04695
LSGGAMVRLEPEDQV	C1QTNF5	191	Q9BXJ0
VQQALRLAQPGMGGA	DACT3	41	Q96B18
MVGGVHPEAAVRVVQ	CPLANE1	926	Q9H799
AAGVRLIGEMPQEDL	GLT1D1	221	Q96MS3
MISLEGPFNRDVVEG	CCDC81	111	Q6ZN84
PPIIEGNMEAARAVD	CNTN1	656	Q12860
MNRGINEGGDLPEEL	CYTH2	216	Q99418
GLQQAPGIGRAVAEM	FOXRED1	441	Q96CU9
EPGVVGQMIEAAEER	CANX	466	P27824
VPEAVGGDMQQLNQL	COMMD7	11	Q86VX2
GAAEAEIMNLPERVG	CXXC4	51	Q9H2H0
MNRGINEGGDLPEEL	CYTH3	221	O43739
GERQGMLEEVVNPEA	CYP11A1	216	P05108
RQIGMAEAEGAVPFL	CSAD	226	Q9Y600
EIRPTGGQLIEGENM	FCRL3	291	Q96P31
ERMNTLLANGEVPGL	DYNC1H1	3006	Q14204
DGVVPDTELEGRMQQ	LAMC2	641	Q13753
DQVVGRDRLPCMGDQ	CYP1B1	361	Q16678
ADGRIEPGDMLLQVN	DVL1	291	O14640
MPLVDQLENRLGGEE	HEATR1	2021	Q9H583
LLGGGDEEAIRPQMQ	ECE1	291	P42892
MQAPRELAVGIDLGT	HSPA6	1	P17066
PVAQVLRNVMEADGI	DGKE	331	P52429
RLVENDVAGIDVNMG	DUS2	101	Q9NX74
ADGRIEPGDMLLQVN	DVL1P1	291	P54792
GDRVMAINGIPTEDS	GRIP1	521	Q9Y3R0
RGGVVLDREGQMDNP	DNAH2	3711	Q9P225
MVQQAELGQRVGLFP	HCN2	701	Q9UL51
ALERMQGETGPNVGL	CREB3L4	121	Q8TEY5
VGIDGANPVELLAMA	COL6A6	946	A6NMZ7
PREMVAQFLLVDGNV	NRROS	296	Q86YC3
KMGTPAEQAQGERNV	MICAL2	1511	O94851
NIIAMGFPAERLEGV	PTEN	31	P60484
QVLIGDEPERGMENL	HGH1	336	Q9BTY7
QAGVQVGMRVVRGVD	MIB2	6	Q96AX9
GTIAFMAPEVLRGQQ	MAP3K1	1411	Q13233
AERDVPDPQQGVGME	NUTM2B	656	A6NNL0
AGRMPGQLNVLLAEA	NNT	966	Q13423
ALEPRQASQGMVGQL	RUVBL2	36	Q9Y230
AGPMRQISLVGAVDE	RSBN1	471	Q5VWQ0
GPMRQISLVGAVDEE	RSBN1L	461	Q6PCB5
VGIIQAAELPALDMG	SYT1	161	P21579
ARVEPAAMLNGEGLQ	SYNPO2L	406	Q9H987
ERGLFRGIEDNPMVV	VARS1	646	P26640
GAQMNGIQPEEIGRL	USO1	721	O60763
PGAQIVMVAGLDNAV	UTP18	261	Q9Y5J1
IMGRGGDNVQVAVVP	TRIM45	431	Q9H8W5
VLQPGAGAIMARIAQ	ACAA1	91	P09110
ETGLNVPRDQLQGML	SEL1L3	581	Q68CR1
GGVSLVEQMFQDPRL	HARS2	276	P49590
QRVTMGPEEVLIQAG	SSPOP	246	A2VEC9
SLEIGENRLVMGGPQ	PIH1D1	236	Q9NWS0
LGAQMEAARPLVQEN	SYNE3	601	Q6ZMZ3
AGDHPGRAVQTLQME	GFPT1	316	Q06210
NLGVIFGPTLMRAQE	ARHGAP42	531	A6NI28
QVGNIPGRLVAEMEV	RIMBP3	1506	Q9UFD9
PMGIVLDALEQQEEG	ARL6IP5	161	O75915
PVMENAQGLGFRNVV	HDHD5	141	Q9BXW7
RQGAEGLMAPDVHIQ	PRR20C	101	P86479
MEVQRGQFQGRPVSV	EPPK1	3176	P58107
RQGAEGLMAPDVHIQ	PRR20E	101	P86478
QEDEQFLGAVMPRLG	SEPHS1	51	P49903
RPNIILVMADDLGIG	STS	26	P08842
AIRESGMNLNPEVEG	MRRF	161	Q96E11
GMNLNPEVEGTLIRV	MRRF	166	Q96E11
VIIRMNNGPVLGHEE	ST3GAL6	141	Q9Y274
ELIDQLGGPQRVAEM	SBNO2	736	Q9Y2G9
AGAVVAMPLAGVLVQ	SLC17A7	216	Q9P2U7
GDDRVLVMGATNRPQ	SPAST	476	Q9UBP0
PEGIARLANSGINVM	SP1	756	P08047
MAGVRPDNVAEVVAG	KBTBD11	196	O94819
VQRLGMLEAGILPQE	SPTBN5	466	Q9NRC6
MLEAGILPQEGRFQA	SPTBN5	471	Q9NRC6
MNNIIEPRGEQGDGL	SPICE1	686	Q8N0Z3
EGMRVVVNALLGAIP	SCN1A	1331	P35498
GAGPSVAAVREIMEN	TET1	1441	Q8NFU7
VADMENGNIEGIPER	AKAP6	1891	Q13023
GAKMILPEGIQRENN	ASCC3	421	Q8N3C0
IVRGRVSAADNGEPM	CILP	491	O75339
QRLGARVASVDMGPQ	CNDP1	86	Q96KN2
VIGQVRRPEMGDQAH	CYP2D7	356	A0A087X1C5
VLEMVAELAGQQDPG	RNF31	531	Q96EP0
EPEEMARQLLAVFGG	TMEM268	281	Q5VZI3
DGIAMLVAGNDRVQA	TRIM54	176	Q9BYV2
VAGMERQTQLGELPN	TULP4	301	Q9NRJ4
VIFGSVEMGRIIQNP	TULP4	756	Q9NRJ4
LGQRIPAGAVLEMAV	TBXAS1	421	P24557
MLEQLRQVNGIDPNG	STXBP6	81	Q8NFX7
QEGSPERAQGMATLV	TEX13D	476	A0A0J9YY54
VNEMRPGEGQASQEL	ZSCAN5DP	166	P0CG00
GMEGEVLPKNIQRAA	RALGAPA1	326	Q6GYQ0
GAGVAMDGQDVQLPL	VWF	461	P04275
SLVDVMQREGGPSQI	VWF	1756	P04275
MATRPAGQNLQGIED	PHIP	406	Q8WWQ0
LAPLQDVDVGAGEMA	SPEG	971	Q15772
MEEGVVNEILQGPLR	TUBE1	76	Q9UJT0
EEPGVRNGMASEGLN	PSD2	26	Q9BQI7
GGIAQIIAAQEEMLR	TLN1	2496	Q9Y490
GFQEGVSMEVLERNP	SH3PXD2A	1091	Q5TCZ1
EAEMLRDPEGGQQVS	TEDC1	216	Q86SX3
IAVQVNNGDAGREMP	SP100	251	P23497
NGQLAPGITMTEIDR	RORB	211	Q92753
EGMRVVVNALLGAIP	SCN2A	1321	Q99250
MDDLRAQILGGANTP	UBE2T	31	Q9NPD8
GDQGELPIAMALANV	NF1	1216	P21359
LRIPQGTVGQVMLDD	NUP188	511	Q5SRE5
EGMRVVVNALVGAIP	SCN8A	1311	Q9UQD0
PLAMQTERGNGLQAV	SPTBN4	1536	Q9H254
APVEGVAGEQRVMAL	SPTA1	971	P02549
QGLQCEREGIQRMTP	TEK	336	Q02763
PEVMAEDILGVQAAR	PIGZ	66	Q86VD9
DRFEVQGLQPNGEEM	UBA1	956	P22314
ARRALAGLMPEVQVE	SMUG1	221	Q53HV7
MEQGSGRLEDFPVNV	TMEM174	1	Q8WUU8
LGDPFLQERGLEQMA	ZNF70	31	Q9UC06
DIGFGPLQQRMSEEV	ZNF484	81	Q5JVG2
LLEQMGAASRVGVPE	SLC39A8	51	Q9C0K1
PQDEGANTRMGLLQE	TTC16	396	Q8NEE8
EGRVQMVVIQGEGRA	ZNF142	821	P52746
LGAGPNVAAIREIME	TET2	1151	Q6N021
NIELISGQNERMGPL	USP8	361	P40818
FGGEDIMQNPVRLIQ	KLHL38	436	Q2WGJ6
MAQEVDPEGDRTIGI	MX1	231	P20591
PNSVQGVDDMIRLGD	MYO7B	61	Q6PIF6
FPEVMGLATNREAQG	MYO7B	1451	Q6PIF6
GMGRAEQVIFVRETP	NECTIN2	336	Q92692