Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.41e-1911414118GO:0004843
GeneOntologyMolecularFunctiondeubiquitinase activity

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

6.81e-1912414118GO:0101005
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

4.32e-1813714118GO:0019783
GeneOntologyMolecularFunctioncysteine-type peptidase activity

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.92e-1519214118GO:0008234
GeneOntologyMolecularFunctionpeptidase activity

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 DPP9 USP17L17 USP17L3 CORIN USP17L22 USP17L15 PROC USP17L8 USP17L13

6.72e-0965414121GO:0008233
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP2E1 P3H3 JMJD4 P3H2 TET1 PAH TPH2 TET3 TPH1

9.94e-061941419GO:0016705
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen

PAH TPH2 TPH1

1.18e-0571413GO:0016714
GeneOntologyMolecularFunctioniron ion binding

CYP2E1 P3H3 ADO P3H2 TET1 PAH TPH2 TPH1

2.39e-051661418GO:0005506
GeneOntologyMolecularFunctiontryptophan 5-monooxygenase activity

TPH2 TPH1

4.95e-0521412GO:0004510
GeneOntologyMolecularFunctiondioxygenase activity

P3H3 JMJD4 ADO P3H2 TET1 TET3

6.88e-05981416GO:0051213
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

P3H3 JMJD4 P3H2 TET1 TET3

9.61e-05651415GO:0016706
GeneOntologyMolecularFunctionprocollagen-proline 3-dioxygenase activity

P3H3 P3H2

1.48e-0431412GO:0019797
GeneOntologyMolecularFunction5-methylcytosine dioxygenase activity

TET1 TET3

1.48e-0431412GO:0070579
GeneOntologyMolecularFunctionpeptidyl-proline 3-dioxygenase activity

P3H3 P3H2

2.94e-0441412GO:0031544
GeneOntologyMolecularFunctionkeratin filament binding

EPPK1 FAM83H

7.29e-0461412GO:1990254
GeneOntologyMolecularFunctionprocollagen-proline dioxygenase activity

P3H3 P3H2

1.35e-0381412GO:0019798
GeneOntologyMolecularFunctionhistone H3K4 monomethyltransferase activity

KMT2B KMT2C

1.35e-0381412GO:0140945
GeneOntologyMolecularFunctionphospholipase binding

DGKQ PLA2R1 PTPN11

1.47e-03321413GO:0043274
GeneOntologyBiologicalProcessprotein deubiquitination

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.64e-1912513718GO:0016579
GeneOntologyBiologicalProcessprotein modification by small protein removal

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.63e-1814413718GO:0070646
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

USP17L7 TRIM72 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 LRRK2 USP17L5 RNF213 USP17L10 USP17L19 MED1 USP17L18 USP17L17 ASB6 TRIM17 NT5C2 DZIP3 USP17L3 HERC6 USP17L22 USP17L15 USP17L8 WDR24 USP17L13

9.53e-11100913728GO:0070647
GeneOntologyBiologicalProcesspost-translational protein modification

USP17L7 TRIM72 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 LRRK2 USP17L5 RNF213 USP17L10 USP17L19 MED1 USP17L18 USP17L17 ASB6 TRIM17 NT5C2 DZIP3 USP17L3 HERC6 USP17L22 USP17L15 USP17L8 WDR24 USP17L13

3.96e-10107413728GO:0043687
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

USP17L7 USP17L21 PNPLA2 USP17L4 USP17L12 USP17L1 CYP2E1 USP17L20 USP17L11 LRRK2 RDH10 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 CYB5R3 USP17L3 USP17L22 TNPO3 USP17L15 SOAT2 USP17L8 USP17L13 SPINK5

2.05e-06132713925GO:0042175
GeneOntologyCellularComponentendoplasmic reticulum membrane

USP17L7 USP17L21 PNPLA2 USP17L4 USP17L12 USP17L1 CYP2E1 USP17L20 USP17L11 LRRK2 RDH10 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 CYB5R3 USP17L3 USP17L22 USP17L15 SOAT2 USP17L8 USP17L13 SPINK5

4.37e-06129313924GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

USP17L7 USP17L21 PNPLA2 USP17L4 USP17L12 USP17L1 CYP2E1 USP17L20 USP17L11 LRRK2 RDH10 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 CYB5R3 USP17L3 USP17L22 USP17L15 SOAT2 USP17L8 USP17L13 SPINK5

4.72e-06129913924GO:0098827
DomainHABP4_PAI-RBP1

USP17L7 USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L13

5.46e-261613713PF04774
DomainHABP4_PAIRBP1-bd

USP17L7 USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L13

5.46e-261613713IPR006861
DomainUCH

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13

1.37e-217113717PF00443
DomainUSP_2

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13

1.37e-217113717PS00973
DomainUSP_3

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13

1.79e-217213717PS50235
DomainUSP_dom

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13

1.79e-217213717IPR028889
DomainPeptidase_C19_UCH

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13

1.79e-217213717IPR001394
DomainUSP_CS

USP17L7 USP17L21 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13

1.79e-206613716IPR018200
DomainUSP_1

USP17L7 USP17L21 USP17L4 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13

5.07e-207013716PS00972
DomainACT_dom

PAH TPH2 TPH1

3.86e-0731373IPR002912
DomainACT

PAH TPH2 TPH1

3.86e-0731373PS51671
DomainACT

PAH TPH2 TPH1

3.86e-0731373PF01842
Domain-

PAH TPH2 TPH1

1.54e-06413731.10.800.10
DomainArAA_hydroxylase_Fe/CU_BS

PAH TPH2 TPH1

1.54e-0641373IPR018301
DomainBH4_AAA_HYDROXYL_2

PAH TPH2 TPH1

1.54e-0641373PS51410
DomainArAA_hydroxylase

PAH TPH2 TPH1

1.54e-0641373IPR001273
DomainBiopterin_H

PAH TPH2 TPH1

1.54e-0641373PF00351
DomainTyrosine_3-monooxygenase-like

PAH TPH2 TPH1

1.54e-0641373IPR019773
DomainAromatic-AA_hydroxylase_C

PAH TPH2 TPH1

1.54e-0641373IPR019774
DomainBH4_AAA_HYDROXYL_1

PAH TPH2 TPH1

1.54e-0641373PS00367
DomainVWC

CHRDL2 KCP MUC5B BMPER MUC5AC

1.69e-06281375PF00093
DomainUnchr_dom_Cys-rich

KCP MUC5B BMPER MUC5AC

1.88e-06131374IPR014853
DomainC8

KCP MUC5B BMPER MUC5AC

1.88e-06131374SM00832
DomainTIL_dom

KCP MUC5B BMPER MUC5AC

2.62e-06141374IPR002919
DomainVWF_type-D

KCP MUC5B BMPER MUC5AC

4.71e-06161374IPR001846
DomainVWFD

KCP MUC5B BMPER MUC5AC

4.71e-06161374PS51233
DomainVWD

KCP MUC5B BMPER MUC5AC

4.71e-06161374SM00216
DomainVWD

KCP MUC5B BMPER MUC5AC

4.71e-06161374PF00094
DomainVWFC_1

CHRDL2 KCP MUC5B BMPER MUC5AC

6.20e-06361375PS01208
DomainVWFC_2

CHRDL2 KCP MUC5B BMPER MUC5AC

8.15e-06381375PS50184
DomainVWC

CHRDL2 KCP MUC5B BMPER MUC5AC

8.15e-06381375SM00214
DomainVWF_dom

CHRDL2 KCP MUC5B BMPER MUC5AC

1.35e-05421375IPR001007
DomainTrp_5_mOase

TPH2 TPH1

5.34e-0521372IPR005963
DomainC8

MUC5B BMPER MUC5AC

8.09e-05121373PF08742
DomainTIL

MUC5B BMPER MUC5AC

8.09e-05121373PF01826
DomainVWC_out

KCP MUC5B MUC5AC

3.43e-04191373SM00215
DomainFYrich_C

KMT2B KMT2C

5.26e-0451372IPR003889
DomainFYrich_N

KMT2B KMT2C

5.26e-0451372IPR003888
DomainFYRC

KMT2B KMT2C

5.26e-0451372SM00542
DomainFYRN

KMT2B KMT2C

5.26e-0451372SM00541
DomainFYRN

KMT2B KMT2C

5.26e-0451372PF05964
DomainFYRC

KMT2B KMT2C

5.26e-0451372PF05965
DomainFYRC

KMT2B KMT2C

5.26e-0451372PS51543
DomainFYRN

KMT2B KMT2C

5.26e-0451372PS51542
DomainWxxW_domain

MUC5B MUC5AC

7.86e-0461372IPR025155
DomainMucin2_WxxW

MUC5B MUC5AC

7.86e-0461372PF13330
DomainAT_hook

KMT2B AHDC1 KMT2C

9.93e-04271373SM00384
DomainAT_hook_DNA-bd_motif

KMT2B AHDC1 KMT2C

9.93e-04271373IPR017956
DomainIGc2

HSPG2 L1CAM OBSCN FGFRL1 LILRB1 ALPK3 CLMP

1.76e-032351377SM00408
DomainIg_sub2

HSPG2 L1CAM OBSCN FGFRL1 LILRB1 ALPK3 CLMP

1.76e-032351377IPR003598
DomainIg_I-set

HSPG2 L1CAM OBSCN FGFRL1 ALPK3 CLMP

2.80e-031901376IPR013098
DomainI-set

HSPG2 L1CAM OBSCN FGFRL1 ALPK3 CLMP

2.80e-031901376PF07679
DomainZF_CXXC

KMT2B TET1

2.81e-03111372PS51058
DomainZnf_CXXC

KMT2B TET1

2.81e-03111372IPR002857
Domain2OG-FeII_Oxy_3

P3H3 P3H2

2.81e-03111372PF13640
Domainzf-CXXC

KMT2B TET1

2.81e-03111372PF02008
PathwayREACTOME_RAS_PROCESSING

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.46e-26459917MM15671
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 MAT2B USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.02e-151919918MM15289
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L21 USP17L4 USP17L12 USP17L1 MAT2B USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.34e-142219918M27578
PathwayREACTOME_DEUBIQUITINATION

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 MAT2B USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.56e-132629918MM15286
PathwayREACTOME_DEUBIQUITINATION

USP17L21 USP17L4 USP17L12 USP17L1 MAT2B USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.42e-122999918M27574
PathwayREACTOME_MAPK_FAMILY_SIGNALING_CASCADES

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 PTPN11 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

6.82e-123189918MM15278
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

USP17L7 USP17L21 PNPLA2 USP17L4 USP17L12 USP17L1 MAT2B USP17L20 USP17L11 JMJD4 USP17L5 USP17L10 MUC5B USP17L19 USP17L18 USP17L17 ASB6 USP17L3 CAPZA3 USP17L22 MUC5AC USP17L15 PROC USP17L8 USP17L13

7.65e-0613899925MM15307
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

USP17L21 PNPLA2 USP17L4 USP17L12 USP17L1 MAT2B USP17L20 USP17L11 USP17L24 JMJD4 USP17L5 USP17L10 MUC5B USP17L19 USP17L18 USP17L17 ASB6 USP17L3 CAPZA3 USP17L22 MUC5AC USP17L15 PROC USP17L8 USP17L13

2.17e-0514759925M19806
PathwayREACTOME_SEROTONIN_AND_MELATONIN_BIOSYNTHESIS

TPH2 TPH1

4.82e-045992MM14831
PathwayREACTOME_SEROTONIN_AND_MELATONIN_BIOSYNTHESIS

TPH2 TPH1

4.82e-045992M27119
PathwayKEGG_MEDICUS_REFERENCE_SEROTONIN_METABOLISM

TPH2 TPH1

4.82e-045992M47902
Pubmed

DUB-1, a deubiquitinating enzyme with growth-suppressing activity.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

4.69e-3821141178622927
Pubmed

DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

4.69e-38211411714583620
Pubmed

DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

4.69e-38211411711468161
Pubmed

The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

4.69e-3821141178756639
Pubmed

Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

4.69e-38211411712447969
Pubmed

DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

4.69e-38211411718980247
Pubmed

JAK2 is required for induction of the murine DUB-1 gene.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.06e-3722141179154835
Pubmed

DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.68e-3624141178995226
Pubmed

Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

8.36e-36251411721115691
Pubmed

Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.41e-35261411735816173
Pubmed

Cdc25A and Dub3 in a high-stakes balancing act.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.79e-35331411820228807
Pubmed

The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.92e-35341411820403174
Pubmed

DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.92e-35341411814699124
Pubmed

The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.92e-35341411815780755
Pubmed

USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.92e-35341411819188362
Pubmed

Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.92e-35341411811941478
Pubmed

Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.92e-35341411817109758
Pubmed

The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.92e-35341411820388806
Pubmed

Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.92e-35341411820715989
Pubmed

Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.92e-3534141189806828
Pubmed

The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.92e-35341411820368735
Pubmed

The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.92e-35341411810936051
Pubmed

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.92e-35341411821448158
Pubmed

Cytokine-regulated protein degradation by the ubiquitination system.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.21e-34351411816611142
Pubmed

Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.21e-34351411821239494
Pubmed

The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.42e-34361411820147298
Pubmed

Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.96e-34291411732527007
Pubmed

Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

4.70e-34371411820228808
Pubmed

DUX is a non-essential synchronizer of zygotic genome activation.

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

6.99e-29501411731806660
Pubmed

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.

USP17L7 USP17L21 USP17L4 ZNF672 USP17L12 USP17L1 INHA USP17L20 USP17L11 LRRK2 USP17L5 USP17L10 USP17L19 USP17L18 PLA2R1 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

5.04e-136741412137196079
Pubmed

High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.

USP17L7 USP17L4 USP17L1 USP17L3 USP17L15 USP17L8

8.26e-1310141624207026
Pubmed

Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.

USP17L7 USP17L4 USP17L1 USP17L3 USP17L15 USP17L8

3.61e-1212141624695638
Pubmed

ES cell neural differentiation reveals a substantial number of novel ESTs.

USP17L7 USP17L4 USP17L1 USP17L3 USP17L15 USP17L8

1.17e-1114141611793228
Pubmed

CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.

USP17L7 USP17L4 USP17L1 USP17L3 USP17L15 USP17L8

1.04e-1019141628067227
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 HSPG2 PNPLA2 EPPK1 KMT2B ACACA L1CAM RDH10 OBSCN DGKQ FGFRL1 AHDC1 FAM83H PPP1R26 KMT2C TRAF4 MROH1 SH3TC1 PIK3C2B PPP1R15B TNFAIP2 TNPO3 WDR24

1.25e-1011051412335748872
Pubmed

Phenylalanine hydroxylase contributes to serotonin synthesis in mice.

PAH TPH2 TPH1

6.52e-083141333993565
Pubmed

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

USP17L21 USP17L12 USP17L20 USP17L11 USP17L19 USP17L18 USP17L17

5.95e-07119141728625976
Pubmed

Human and mouse proteases: a comparative genomic approach.

USP17L7 USP17L4 USP17L1 USP17L3 USP17L15 USP17L8

1.01e-0681141612838346
Pubmed

DNA sequence and analysis of human chromosome 8.

USP17L7 USP17L4 USP17L1 USP17L3 USP17L8

1.52e-0648141516421571
Pubmed

DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.

KMT2B TET1 TET3

7.67e-0610141329276034
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

USP17L7 KMT2B ACACA USP17L12 CDKL2 OBSCN RNF213 KMT2C ADO RECQL4 USP17L3 FUBP3 RPL12

1.02e-057361411329676528
Pubmed

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

MUC5B MUC5AC

1.63e-05214127513696
Pubmed

Attention-deficit/hyperactivity disorder symptoms in offspring of mothers with impaired serotonin production.

TPH2 TPH1

1.63e-052141220921119
Pubmed

The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

MUC5B MUC5AC

1.63e-052141237146737
Pubmed

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

MUC5B MUC5AC

1.63e-052141214988081
Pubmed

Association of functional polymorphisms of the human tryptophan hydroxylase 2 gene with risk for bipolar disorder in Han Chinese.

TPH2 TPH1

1.63e-052141217768266
Pubmed

MLL4 binds TET3.

KMT2B TET3

1.63e-052141238579707
Pubmed

Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.

MUC5B MUC5AC

1.63e-052141215563276
Pubmed

The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.

MUC5B MUC5AC

1.63e-052141217621824
Pubmed

Muc5b is required for airway defence.

MUC5B MUC5AC

1.63e-052141224317696
Pubmed

Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.

MUC5B MUC5AC

1.63e-052141222391959
Pubmed

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

MUC5B MUC5AC

1.63e-052141235776514
Pubmed

The ocular surface phenotype of Muc5ac and Muc5b null mice.

MUC5B MUC5AC

1.63e-052141224327612
Pubmed

Common variants in the TPH1 and TPH2 regions are not associated with persistent ADHD in a combined sample of 1,636 adult cases and 1,923 controls from four European populations.

TPH2 TPH1

1.63e-052141220213726
Pubmed

Specific glycoforms of MUC5AC and endorepellin accurately distinguish mucinous from nonmucinous pancreatic cysts.

HSPG2 MUC5AC

1.63e-052141223836919
Pubmed

Predominant expression of tryptophan hydroxylase 1 mRNA in the pituitary: a postmortem study in human brain.

TPH2 TPH1

1.63e-052141219233335
Pubmed

Gel-forming mucins form distinct morphologic structures in airways.

MUC5B MUC5AC

1.63e-052141228607090
Pubmed

Src homology 2-containing protein tyrosine phosphatase-2 acts as a negative regulator for MUC5AC transcription via the inhibition of the ERK1/2 MAPK signalling pathway in the airway.

PTPN11 MUC5AC

1.63e-052141223582017
Pubmed

Family-based association study of TPH1 and TPH2 polymorphisms in autism.

TPH2 TPH1

1.63e-052141216958027
Pubmed

The role of the TPH1 and TPH2 genes for nicotine dependence: a genetic association study in two different age cohorts.

TPH2 TPH1

1.63e-052141217986837
Pubmed

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.

MUC5B MUC5AC

1.63e-052141231030254
Pubmed

Synthesis of serotonin by a second tryptophan hydroxylase isoform.

TPH2 TPH1

1.63e-052141212511643
Pubmed

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.

MUC5B MUC5AC

1.63e-052141223527003
Pubmed

Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.

MUC5B MUC5AC

1.63e-052141216540890
Pubmed

DNAJC12 deficiency: A new strategy in the diagnosis of hyperphenylalaninemias.

PAH DNAJC12

1.63e-052141229174366
Pubmed

Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants.

TPH2 TPH1

1.63e-052141218923670
Pubmed

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

MUC5B MUC5AC

1.63e-052141227845589
Pubmed

Role of Tet1/3 Genes and Chromatin Remodeling Genes in Cerebellar Circuit Formation.

TET1 TET3

1.63e-052141226711116
Pubmed

Expression, purification and enzymatic characterization of the catalytic domains of human tryptophan hydroxylase isoforms.

TPH2 TPH1

1.63e-052141219816759
Pubmed

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

MUC5B MUC5AC

1.63e-052141227435107
Pubmed

Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.

MUC5B MUC5AC

1.63e-052141226871672
Pubmed

Common genetic variations in TPH1/TPH2 genes are not associated with schizophrenia in Japanese population.

TPH2 TPH1

1.63e-052141220144688
Pubmed

A unique central tryptophan hydroxylase isoform.

TPH2 TPH1

1.63e-052141214563478
Pubmed

In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.

MUC5B MUC5AC

1.63e-052141211587997
Pubmed

Human placenta expresses both peripheral and neuronal isoform of tryptophan hydroxylase.

TPH2 TPH1

1.63e-052141228751217
Pubmed

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

MUC5B MUC5AC

1.63e-052141234656442
Pubmed

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

MUC5B MUC5AC

1.63e-052141234058148
Pubmed

Maternal serotonin is crucial for murine embryonic development.

TPH2 TPH1

1.63e-052141217182745
Pubmed

Association between single nucleotide polymorphisms of TPH1 and TPH2 genes, and depressive disorders.

TPH2 TPH1

1.63e-052141229314569
Pubmed

C-Mannosylation of MUC5AC and MUC5B Cys subdomains.

MUC5B MUC5AC

1.63e-052141214718370
Pubmed

TPH2 and TPH1: association of variants and interactions with heroin addiction.

TPH2 TPH1

1.63e-052141218181017
Pubmed

Association of TPH-1 and TPH-2 gene polymorphisms with suicidal behavior: a systematic review and meta-analysis.

TPH2 TPH1

1.63e-052141225005534
Pubmed

Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies.

TPH2 TPH1

1.63e-052141216581041
Pubmed

Mucin production during prenatal and postnatal murine lung development.

MUC5B MUC5AC

1.63e-052141221653907
Pubmed

Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.

TET1 TET3

1.63e-052141226703470
Pubmed

Associations of tryptophan hydroxylase gene polymorphisms with irritable bowel syndrome.

TPH2 TPH1

1.63e-052141221073637
Pubmed

MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.

MUC5B MUC5AC

1.63e-052141236427316
Pubmed

Hypoxia Drives Breast Tumor Malignancy through a TET-TNFα-p38-MAPK Signaling Axis.

TET1 TET3

1.63e-052141226294212
Pubmed

Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function.

TPH2 TPH1

1.63e-052141214597720
Pubmed

Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice.

TPH2 TPH1

1.63e-052141219181488
Pubmed

Mucin deficiency causes functional and structural changes of the ocular surface.

MUC5B MUC5AC

1.63e-052141223272068
Pubmed

Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.

MUC5B MUC5AC

1.63e-052141227729120
Pubmed

The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer.

P3H3 P3H2

1.63e-052141219436308
Pubmed

De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.

MUC5B MUC5AC

1.63e-052141236111525
Pubmed

Genetic, Psychological, and Personal Network Factors Associated With Changes in Binge Drinking Over 2 Years Among Mexican Heritage Adolescents in the USA.

TPH2 TPH1

1.63e-052141229697747
Pubmed

Isoform-Specific Substrate Inhibition Mechanism of Human Tryptophan Hydroxylase.

TPH2 TPH1

1.63e-052141229035515
Pubmed

The tryptophan hydroxylase gene influences risk for bipolar disorder but not major depressive disorder: results of meta-analyses.

TPH2 TPH1

1.63e-052141219032713
Pubmed

LEPREL1, a novel ER and Golgi resident member of the Leprecan family.

P3H3 P3H2

1.63e-052141215063763
Pubmed

Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.

MUC5B MUC5AC

1.63e-052141232348677
Pubmed

Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.

MUC5B MUC5AC

1.63e-052141224332705
InteractionFLT3 interactions

USP17L21 EPPK1 USP17L12 USP17L20 USP17L11 RNF213 USP17L19 USP17L18 PTPN11 USP17L17 TNPO3

9.32e-0631813411int:FLT3
InteractionTPH2 interactions

TPH2 DNAJC12 TPH1

9.87e-0671343int:TPH2
InteractionTOP3B interactions

VWA5B2 HSPG2 PNPLA2 EPPK1 KMT2B ACACA L1CAM RDH10 OBSCN DGKQ FGFRL1 AHDC1 ZFP36 FAM83H PPP1R26 KMT2C TRAF4 MROH1 SH3TC1 PIK3C2B PPP1R15B TNFAIP2 FUBP3 TNPO3 WDR24

1.18e-05147013425int:TOP3B
Cytoband4p16.1

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 SH3TC1 USP17L17 USP17L22 USP17L15 USP17L13

3.59e-2179141144p16.1
CytobandEnsembl 112 genes in cytogenetic band chr4p16

USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 DGKQ FGFRL1 USP17L10 USP17L19 USP17L18 SH3TC1 USP17L17 USP17L22 USP17L15 USP17L13

1.46e-1722214116chr4p16
Cytoband8p23.1

USP17L7 USP17L4 USP17L1 USP17L3 USP17L8

1.19e-0415414158p23.1
Cytoband8q24.3

EPPK1 FAM83H MROH1 RECQL4

4.24e-0411314148q24.3
CytobandEnsembl 112 genes in cytogenetic band chr8p23

USP17L7 USP17L4 USP17L1 USP17L3 USP17L8

8.12e-042341415chr8p23
GeneFamilyZinc fingers CXXC-type

KMT2B TET1 TET3

1.65e-0512783136
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

HSPG2 L1CAM OBSCN FGFRL1 ALPK3 CLMP

6.87e-05161786593
GeneFamilyRing finger proteins

TRIM72 RNF213 ZFP36 TRAF4 TRIM17 DZIP3

1.20e-0327578658
CoexpressionMADAN_DPPA4_TARGETS

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

2.51e-228614017MM1312
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

3.02e-2011214017MM1095
CoexpressionGERY_CEBP_TARGETS

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

1.56e-1716014017MM1155
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 DGKQ USP17L10 USP17L19 FAM83H USP17L18 PLA2R1 TRAF4 PTPN11 USP17L17 RECQL4 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

6.35e-1364714023MM981
CoexpressionGRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP

USP17L7 USP17L21 PNPLA2 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 RDH10 USP17L5 DGKQ USP17L10 USP17L19 ZFP36 FAM83H USP17L18 PLA2R1 TRAF4 PTPN11 USP17L17 TRIM17 RECQL4 PTRH1 USP17L3 USP17L22 USP17L15 USP17L8 TECPR1 USP17L13

1.13e-11122614029MM979
CoexpressionBRUINS_UVC_RESPONSE_LATE

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 P3H3 USP17L20 USP17L11 USP17L5 FGFRL1 USP17L10 USP17L19 SVEP1 USP17L18 PTPN11 USP17L17 USP17L3 BMPER HERC6 USP17L22 KCNAB3 USP17L15 USP17L8 USP17L13

2.18e-08119814024MM1062
CoexpressionMARSON_BOUND_BY_FOXP3_STIMULATED

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 MAT2B USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 LRP10 USP17L17 TRIM17 DZIP3 USP17L3 MLLT3 USP17L22 USP17L15 USP17L8 USP17L13

5.98e-08107214022MM1031
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

VWA5B2 PAH DNAJC12 UNC79 RPS6KL1 UNC80 TPH1

5.16e-0715913377747cef94c55144fddcd024a7495318357f1351b
ToppCellBasal_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

VWA5B2 EPPK1 APCDD1L BMPER SOAT2 PROC SPINK5

6.36e-07164133785487a303194f5244956ec1ca2d1758d38117f41
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1B L1CAM ASB6 KIF25-AS1 UNC79 UNC80 TPH1

2.09e-0619613374bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCellmild-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LRRK2 NAIP ITPRID2 LILRB1 ZFP36 TNFAIP2 TET3

2.39e-062001337934c2efc780318c66d667ca75be0de350361d351
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B CTTNBP2 KCP MUC5B SVEP1 UNC80

8.70e-061601336c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B CTTNBP2 KCP MUC5B SVEP1 UNC80

8.70e-06160133625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCelldroplet-Lung-LUNG-1m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTF2A1L FGD2 NET1 PKD1L3 TRAF4 TRIM17

1.07e-0516613366e6075d0c913e2516083f6dcab21d5878bcef7a4
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTF2A1L FGD2 NET1 PKD1L3 TRAF4 TRIM17

1.07e-0516613364fbe44e0aea197893614cd55f83119aa0f73ee53
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 CACNA1B TENM1 DNAJC12 PROC TPH1

1.15e-0516813364e1b522c7400c9d87f63c00e4e1dd07136095cd6
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

VWA5B2 CACNA1B DNAJC12 UNC79 UNC80 TPH1

1.19e-051691336b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

L1CAM LRRK2 ZFP36 PIK3C2B PPP1R15B SSH2

1.45e-051751336cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 TTC28 LRRK2 PLA2R1 PIK3C2B RESP18

1.70e-051801336dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-DC1|lymph-node_spleen / Manually curated celltypes from each tissue

CTTNBP2 CYP2E1 NET1 P3H2 CYB5R3 NLRP4

1.70e-051801336a7db1f00566c9acab8b239cbf2e053fb3f2f6a0d
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 TTC28 LRRK2 PLA2R1 PIK3C2B RESP18

1.70e-051801336423454e3390080ae03bb3cbb267255ebfe4df080
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

VWA5B2 CACNA1B DNAJC12 UNC79 UNC80 TPH1

1.81e-05182133657bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 DNAJC12 RESP18 UNC79 PROC TPH1

1.81e-0518213360e589bf97d51b4b2f723f8c45853ad81b7ce8778
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACACA CDKL2 LRRK2 TACC2 P3H2 CORIN

1.86e-0518313366847c1252d6bb105524f812658112517fd351eab
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

VWA5B2 CACNA1B DNAJC12 UNC79 UNC80 TPH1

2.04e-051861336b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

VWA5B2 CACNA1B DNAJC12 UNC79 UNC80 TPH1

2.17e-051881336c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWA5B2 PKD1L3 PAH DNAJC12 UNC80 TPH1

2.30e-05190133640d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWA5B2 PKD1L3 PAH DNAJC12 UNC80 TPH1

2.30e-051901336f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWA5B2 PKD1L3 PAH DNAJC12 UNC80 TPH1

2.30e-051901336a9a705455019e28d655636de73b07540798f82e6
ToppCellwk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

VWA5B2 CACNA1B TENM1 UNC79 UNC80 PROC

2.30e-051901336b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VIPR2 P3H3 SVEP1 PLA2R1 BMPER VEGFD

2.37e-05191133636467322096bc766cd777dae3bfb4e65511e492c
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VIPR2 P3H3 SVEP1 PLA2R1 BMPER VEGFD

2.37e-05191133694795daf05061baa3b72a1b01c9e940af86de044
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VIPR2 P3H3 SVEP1 PLA2R1 BMPER VEGFD

2.37e-051911336c715bbdbbf1482aad45a50a16d5232fd35a9a0bb
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VIPR2 P3H3 SVEP1 PLA2R1 BMPER VEGFD

2.37e-051911336243d83cbfcc4996ad087ec6386e559e0b8662004
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FGD2 LRRK2 NAIP LILRB1 SSH2 TET3

2.37e-05191133647a2afc4102199b4bc76bd01b2967c8016186462
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 KCP SVEP1 CLMP TNFAIP2 BMPER

2.44e-051921336671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 KCP SVEP1 CLMP TNFAIP2 BMPER

2.44e-051921336840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIPR2 ITPRID2 SVEP1 P3H2 CLMP CLUL1

2.44e-05192133620ede290e01ad574afd122d72b59dbc52c595fad
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 SVEP1 TNFAIP2 BMPER VEGFD RPL12

2.44e-0519213362d9e2262f1342fe17735f21f733c029d1275e955
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

CTTNBP2 TTC28 SVEP1 CLMP BMPER VEGFD

2.52e-051931336acad568621ed677031797b8c2e34dafea798d681
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CTTNBP2 TTC28 SVEP1 CLMP BMPER VEGFD

2.59e-051941336011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CDKL2 LRRK2 KCP RNF213 P3H2 SSH2

2.59e-051941336e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

L1CAM DMRT3 KIF25-AS1 UNC79 UNC80 TPH1

2.59e-0519413362dcc3b99dbedaf8a6916891c85091ddb79d7ee31
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

FGD2 NAIP LILRB1 SH3TC1 TNFAIP2 TET3

2.67e-051951336148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

FGD2 NAIP RNF213 LILRB1 TNFAIP2 TET3

2.82e-051971336e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTTNBP2 FGD2 NAIP RNF213 LILRB1 SH3TC1

2.82e-05197133610190b877bf46ba2163d203df9dd3b498c66e52f
ToppCellSepsis-ICU-SEP-Myeloid-cDC2|ICU-SEP / Disease, condition lineage and cell class

FGD2 CYP2E1 NET1 TRAF4 CYB5R3 PROC

3.07e-05200133609d5c3a3d2b42b15c769dc2bc14b6c0d5cc38f91
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Crim1_(Neuron.Gad1Gad2.Cplx3-Crim1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TRIM72 TPH2 ALPK3 SPINK5

3.56e-0562133491c49ae176d2a418a58398e9d5e55c77187cc2fb
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Crim1_(Neuron.Gad1Gad2.Cplx3-Crim1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TRIM72 TPH2 ALPK3 SPINK5

3.56e-056213343275775572a65460b6248ee72b4c85e4d4dee424
ToppCellmetastatic_Brain-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

INHA P3H3 CORIN BMPER UNC79

5.92e-051381335b2ab273f3e62f169b3b9cb82342e6617af99f582
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Vwf)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CYP2E1 KCP VEGFD SOAT2

7.15e-057413340288a3f4eafbc359d01cde4ba58f946dd07c77cb
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CYP2E1 KCP VEGFD SOAT2

7.15e-0574133457884ade66fe39398351685189df5efd7aea0aab
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Vwf)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CYP2E1 KCP VEGFD SOAT2

7.15e-0574133413093139a75bfe11f6b032c9fb402efcc703551c
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Vwf)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CYP2E1 KCP VEGFD SOAT2

7.15e-057413347f7de9e8142d2435391ee965cee5628e412f0705
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CYP2E1 NET1 P3H2 TNFAIP2 PROC

7.49e-051451335f6ba6cf0c8d0ee87a7904485b27eb9261fcb6edd
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

VIPR2 P3H2 DNAJC12 WDR49 PROC

7.73e-051461335bee5074c29b132180d35f57d307e342efa9b8cd1
ToppCellClub_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

MUC5B DMRT3 DNAJC12 CLUL1 MUC5AC

8.51e-05149133581c813588bb5efb7b31141a75d387210dcb76094
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 CACNA1B HSPG2 TPH2 RESP18

1.03e-0415513358fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCellsevere_COVID-19-pDC|severe_COVID-19 / disease group, cell group and cell class (v2)

VIPR2 HSPG2 TTC28 P3H2 PROC

1.16e-041591335ea5088d27e42b8850455764d53b757ea8d8f14bc
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 GARIN2 SH3TC1 ZMAT1 TECPR1

1.19e-04160133533050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CTTNBP2 FGD2 SH3TC1 PPP1R15B ALPK3

1.30e-041631335a6e272e043859858084b8d4d96fa4ff9e6eca454
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 NAIP UNC79 PROC TPH1

1.37e-0416513354b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCellInfluenza_Severe-pDC|Influenza_Severe / Disease group and Cell class

VIPR2 TRAF4 P3H2 DNAJC12 PROC

1.41e-041661335b43a5cd4d28118cf6e56a435deb8ea9435608a90
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|367C / Donor, Lineage, Cell class and subclass (all cells)

FGD2 LILRB1 TNFAIP2 TET3 PROC

1.41e-041661335430d604f5bef9fae20dc81492e6695616f6701a3
ToppCellNS-critical-d_0-4-Epithelial-unknown_epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPPK1 MROH1 ALPK3 KCNAB3 RPS6KL1

1.41e-041661335dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 ACACA GRB7 PAH UNC80

1.41e-041661335eb9c81fa7573de7aff6670e7dad313f02129809f
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

INHA AHDC1 TRAF4 P3H2 PROC

1.45e-041671335bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

VIPR2 ACACA OBSCN PLA2R1 UNC79

1.45e-041671335e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

VWA5B2 CACNA1B DNAJC12 UNC79 UNC80

1.45e-041671335c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

ZNF786 FAM83H TRIM17 UNC79 KCNAB3

1.45e-0416713359efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

ZNF786 FAM83H TRIM17 UNC79 KCNAB3

1.45e-041671335904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 GRB7 DNAJC12 PROC TPH1

1.49e-04168133538ba7737ae0afffcbd3aa499403e83c24a922127
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRRK2 HEXD DPP9 NOC4L SPINK5

1.49e-04168133508f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCellcellseq2-Epithelial-Epithelial_Airway-Secretory/RAS|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

VWA5B2 TRIM72 DGKQ ADO RPS6KL1

1.58e-041701335b62f7184e78e9672ea88e361654f604f9df2dc5f
ToppCellcellseq2-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

VWA5B2 TRIM72 DGKQ ADO RPS6KL1

1.58e-04170133500fe77bca9c28762212c498f9c49e14cb1492cca
ToppCelldroplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 TRAF4 FAM117A MUC5AC RPS6KL1

1.58e-041701335749144a1a869a6bf9acdd227184319083367dc3f
ToppCell10x5'-blood-Myeloid_Dendritic-pDC|blood / Manually curated celltypes from each tissue

TTC28 TRAF4 P3H2 DNAJC12 PROC

1.58e-04170133559cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCelldroplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 TRAF4 FAM117A MUC5AC RPS6KL1

1.58e-04170133525d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EECs|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 CYP2E1 TRIM17 ALPK3 TPH1

1.62e-041711335dd37e1693a5cfc42e40992d504f92048a8038b52
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NET1 TRAF4 FAM117A MUC5AC RPS6KL1

1.67e-041721335422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NET1 TRAF4 FAM117A MUC5AC RPS6KL1

1.67e-0417213351abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RDH10 LRP10 TNFAIP2 HERC6 KIF25-AS1

1.71e-041731335176b956e71d98e8275d698b39437fc326e5fe449
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF449 NET1 TRAF4 TET1 MUC5AC

1.71e-0417313354f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 ACACA TTC28 GRB7 PIK3C2B

1.71e-0417313358bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 ACACA TTC28 GRB7 PIK3C2B

1.71e-0417313353e3c61468e703330788a10d850ef41a85680f86d
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF449 NET1 TRAF4 TET1 MUC5AC

1.71e-0417313359bbea566964281f47bf75d665b7d69ba8326e207
ToppCellsevere_influenza-pDC|severe_influenza / disease group, cell group and cell class (v2)

VIPR2 TRAF4 P3H2 DNAJC12 PROC

1.76e-041741335d8d2ded5812ed3b3db4109585714a6513c13326a
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

CACNA1B PAH UNC79 UNC80 TPH1

1.81e-0417513354db1a3c284488b3f6de7568363f176d74e2a4587
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

CACNA1B PAH UNC79 UNC80 TPH1

1.81e-0417513358d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_early_2|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

EPPK1 ZFP36 CLMP CLUL1 WDR49

1.86e-0417613358e0ac3ad5e47614b4befabd674a40e3eaae553f3
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD141+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

CYP2E1 NET1 LRRK2 P3H2 CYB5R3

1.86e-041761335195393b38f1335f2cb96125616d75c164a6026c2
ToppCellILEUM-inflamed-(3)_pDC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

VIPR2 SH3TC1 NLRP4 WDR49 PROC

1.86e-041761335b9f847dd55703e413f3cd815eef5724fffaf13b3
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIPR2 RDH10 OBSCN DNAJC12 VEGFD

1.91e-041771335bd602db857f37869ef76d14c05ef522c509f08ee
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

NET1 PPP1R26 KCNJ10 DZIP3 DNAJC12

1.91e-041771335e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 DNAJC12 RESP18 PROC TPH1

2.01e-041791335d70791d2a0db35a6b013fa7ed2f9f39364581eff
ToppCelldroplet-Limb_Muscle-nan-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 SVEP1 BMPER VEGFD RPL12

2.06e-041801335d3d0be136fff5d3e39ecf5a5dbefc1d0d0a6c814
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-LYVE1+_Macrophage|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRRK2 NAIP SH3TC1 TNFAIP2 TET3

2.06e-04180133566c7b02d85e32ba3e7530d0c4aff17e7525ccdd8
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

ACACA CDKL2 LRRK2 TACC2 P3H2

2.06e-041801335198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1B CDKL2 L1CAM VEGFD UNC80

2.06e-041801335368ff7fcfd21ad248f96a83a8b191040ba7d8670
ToppCelldroplet-Heart-4Chambers-21m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRB7 ACOT4 FAM83H RESP18 TPH1

2.11e-0418113353fd16229a63de0971db5d48860c01173d7db518f
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 DNAJC12 RESP18 PROC TPH1

2.11e-0418113352392af8c7f040c23a7d416c2e37419954970c8f4
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR2 SVEP1 PLA2R1 BMPER VEGFD

2.17e-041821335c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

P3H3 SVEP1 CLMP BMPER VEGFD

2.17e-04182133519c5e3a9d9b3728303b682102e276adfe93aa759
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR2 SVEP1 PLA2R1 BMPER VEGFD

2.17e-041821335dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCelldroplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRB7 ACOT4 FAM83H RESP18 TPH1

2.22e-0418313354de2082dca2569d3aac3c9b466f27971c82d302b
ToppCellmild-B_cell|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZNF202 GARIN2 PPP1R26 PLA2R1 TRAF4

2.22e-041831335175aaf8fbbff52eab87d78a49d5ab02cd489c438
ToppCelldroplet-Heart-4Chambers-21m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRB7 ACOT4 FAM83H RESP18 TPH1

2.22e-041831335a046b569bc10083d471b420eb2c6fee93437602d
Drug4-vinylcatechol

PAH TPH2 TPH1

1.60e-0651253CID000151398
Diseaseprimary ovarian insufficiency (implicated_via_orthology)

USP17L7 USP17L21 USP17L4 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 DMRT3 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

4.76e-334613719DOID:5426 (implicated_via_orthology)
Diseasecongenital heart disease (implicated_via_orthology)

USP17L7 USP17L21 USP17L4 KMT2B USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 KMT2C USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13

4.88e-316913720DOID:1682 (implicated_via_orthology)
DiseaseAutism Spectrum Disorders

CTTNBP2 TET1 PAH TET3 UNC80

4.88e-05851375C1510586
DiseaseCOVID-19 symptoms measurement

MUC5B DPP9 MUC5AC

5.75e-04351373EFO_0600019
Diseasesystemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus

DGKQ PTPN11 TNPO3

7.33e-04381373EFO_0000685, EFO_0000717, EFO_0000783, MONDO_0007915
DiseaseBMI-adjusted waist circumference, forced expiratory volume

DIS3L2 PTPN11

7.54e-0491372EFO_0004314, EFO_0007789
Diseasehypertrophic cardiomyopathy

GTF2A1L KCP KMT2C ALPK3

9.06e-04921374EFO_0000538
Diseasepulmonary fibrosis

MUC5B MUC5AC

1.15e-03111372EFO_0009448
Diseaserheumatoid arthritis (implicated_via_orthology)

ZFP36 KMT2C

1.37e-03121372DOID:7148 (implicated_via_orthology)
Diseasedepressive disorder (biomarker_via_orthology)

CYP2E1 L1CAM TPH1

1.83e-03521373DOID:1596 (biomarker_via_orthology)
DiseaseHamman-Rich syndrome

MUC5B DPP9

1.88e-03141372C0085786
DiseaseCarcinoma, Granular Cell

CYP2E1 GRB7 KMT2C PTPN11

2.13e-031161374C0205644
DiseaseAdenocarcinoma, Tubular

CYP2E1 GRB7 KMT2C PTPN11

2.13e-031161374C0205645
DiseaseAdenocarcinoma, Oxyphilic

CYP2E1 GRB7 KMT2C PTPN11

2.13e-031161374C0205642
DiseaseCarcinoma, Cribriform

CYP2E1 GRB7 KMT2C PTPN11

2.13e-031161374C0205643
DiseaseAdenocarcinoma, Basal Cell

CYP2E1 GRB7 KMT2C PTPN11

2.13e-031161374C0205641
DiseaseAdenocarcinoma

CYP2E1 GRB7 KMT2C PTPN11

2.13e-031161374C0001418
Diseaseidiopathic pulmonary fibrosis

MUC5B DPP9 MUC5AC

2.39e-03571373EFO_0000768
Diseasecathepsin L1 measurement

LRRK2 TNFAIP2

2.46e-03161372EFO_0010619
Diseasedaytime rest measurement

ACACA LRRK2 TCAIM ADO CAPZA3 PROC

2.61e-032951376EFO_0007828
DiseaseSjogren syndrome

KCP DGKQ TNPO3

2.76e-03601373EFO_0000699
Diseasealpha-L-iduronidase measurement

DGKQ FGFRL1

2.78e-03171372EFO_0020139
Diseasepancreatic ductal carcinoma (is_marker_for)

L1CAM MUC5B MUC5AC

2.89e-03611373DOID:3587 (is_marker_for)
DiseaseUsual Interstitial Pneumonia

MUC5B DPP9

3.47e-03191372C4721509
DiseaseHamman-Rich Disease

MUC5B DPP9

3.47e-03191372C4721508
Diseasebipolar disorder (is_marker_for)

L1CAM TPH2

3.47e-03191372DOID:3312 (is_marker_for)
Diseaselimited scleroderma

DGKQ TNPO3

3.47e-03191372EFO_1001017
Diseaseinterstitial lung disease

MUC5B DPP9 MUC5AC

3.78e-03671373EFO_0004244
Diseaseglaucoma (is_marker_for)

PTPN11 MUC5AC

3.85e-03201372DOID:1686 (is_marker_for)
DiseaseFamilial Idiopathic Pulmonary Fibrosis

MUC5B DPP9

3.85e-03201372C4721952
Diseaseage-related macular degeneration, COVID-19

TACC2 DPP9 CLUL1

4.10e-03691373EFO_0001365, MONDO_0100096
DiseaseIdiopathic Pulmonary Fibrosis

MUC5B DPP9

4.24e-03211372C1800706
Diseasestomach cancer (is_implicated_in)

CYP2E1 KMT2C PTPN11

4.62e-03721373DOID:10534 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
PAHPEAVQAHVLGCF

PTRH1

166

Q86Y79
SQGACAEHLPHRPAV

nan

31

A8MUN3
RLPIEDHKRFHPDCG

NAIP

111

Q13075
VPLCIDGNPVLLSHH

CAPZA3

61

Q96KX2
LFPLAPQEITHCHDE

NT5C2

536

P49902
GPCILTPHRDNLHQI

ADO

181

Q96SZ5
LHLEGHPPVNHLRCE

MLLT3

106

P42568
ASPQPCGLASHEEHR

FAM117A

276

Q9C073
PLICHTGHEQAGREP

ALPK3

61

Q96L96
CGLIARSDVHHPPVL

APCDD1L

256

Q8NCL9
VRALECHPDKHPENP

DNAJC12

36

Q9UKB3
HHIPEDPGHLELCRL

DGKQ

336

P52824
DFEDSAHVPCPRGHV

ACACA

491

Q13085
LLAHGADPSECPAHE

ASB6

246

Q9NWX5
QAHLSCRDLPLGQPH

AHDC1

1441

Q5TGY3
IPEELCGHHLPQQSL

DIS3L2

141

Q8IYB7
ELRNHQPREPHCDLE

CACNA1B

1016

Q00975
QERRVHEETVPLHCP

MUC5B

5706

Q9HC84
HEETVPLHCPNGSAI

MUC5B

5711

Q9HC84
PNLDHVGHPTERCFV

CYB5R3

286

P00387
EHEENPCQLREPCLH

HSPG2

4141

P98160
KEHHQSLDPNCPRDL

CYP2E1

251

P05181
HPVHADNCVLDPDTG

P3H3

581

Q8IVL6
SQERPCHLDLHQREP

KIAA1107

1066

Q9UPP5
CHLDLHQREPNSDIP

KIAA1107

1071

Q9UPP5
PELHEECEGNHPSAR

NET1

516

Q7Z628
PGEDHILEHLPARLN

PNPLA2

291

Q96AD5
SHIFLLCPEHIDQAP

KMT2C

321

Q8NEZ4
AHPDRIIFPNHACED

LRP10

16

Q7Z4F1
QPHVIVHCAAERRPD

MAT2B

86

Q9NZL9
VAHGDLLELDPPANH

KCNJ10

91

P78508
NELICPRENDPVHGA

SPINK5

926

Q9NQ38
RMNHHPLEEDCPPVL

FAM13B

506

Q9NYF5
LCEEHGSPAAPQHLL

FGFRL1

446

Q8N441
PVTLRLPRCGHHEVD

OR2W3

161

Q7Z3T1
QPPHLHFEEQGCEGD

OR2W5P

286

A6NFC9
HLRVDPPETGVSHLC

FAM47B

246

Q8NA70
PPDRCQHAAHIISEL

FUBP3

306

Q96I24
LEDDLLRALPCHSPH

HERC6

461

Q8IVU3
LHPGAQRLHIGCDEV

HEXD

136

Q8WVB3
HRPVIELPHCENSEI

LRRK2

1676

Q5S007
PCLLIQIPEEYEGHH

L1CAM

16

P32004
GVPGHPEALHLECQS

L1CAM

916

P32004
HPFCLEEAERPLPQH

KMT2B

1226

Q9UMN6
DHPHPAVRCVQELLV

NLRP4

471

Q96MN2
CRAESHPEVNIEHLG

MUC5AC

4676

P98088
DHTRVVLHDGDPNEP

PTPN11

286

Q06124
SHPIHADNCLLDPEA

P3H2

576

Q8IVL5
LHGVRHPQDPCSSDA

CHRDL2

191

Q6WN34
LDERGHPNPQTGHCR

KIF25-AS1

101

Q9Y6Z4
DGLVHPDPAILFHTC

MROH1

1021

Q8NDA8
EAPQSEAPRVEECHH

ITPRID2

811

P28290
EAPRVEECHHGRTPT

ITPRID2

816

P28290
TCRLHVLLPEEFPGH

DZIP3

1186

Q86Y13
VECHPHLALERGLED

GRB7

146

Q14451
PDICHELLGHVPLFS

PAH

281

P00439
HLIHAPPEVAECDLV

PIK3C2B

1456

O00750
QHLERCPHVPIAVAG

OBSCN

5721

Q5VST9
VDPHHILIEDPDGSC

OBSCN

6056

Q5VST9
HVDGDQCLVLPLEHP

PROC

86

P04070
CPREEHAVHAVPVDL

PRICKLE3

51

O43900
HASRLHPQEPCLKDG

RESP18

131

Q5W5W9
DPDKRPFCAELLHHD

CDKL2

271

Q92772
ALPCRAPHFHIDLDG

BMPER

446

Q8N8U9
VLHGCPLPRAELDQH

CTTNBP2

1411

Q8WZ74
PKCHAEQNHLLIEGP

DMRT3

221

Q9NQL9
PNERHSIRCPESGEH

DPP9

836

Q86TI2
LCDTHLHPRNQLAGP

JMJD4

281

Q9H9V9
NTGEHIPPCRALCEH

CORIN

521

Q9Y5Q5
SRGPLAPNHVHEVCL

LSMEM2

31

Q8N112
GQRLEDVHHRPECRP

FGD2

31

Q7Z6J4
RPPEEPAAHANCHRV

INHA

251

P05111
LCPEELEHVSRHLRP

FAM83H

56

Q6ZRV2
CRVLVHRPHGPELDA

NOC4L

401

Q9BVI4
AHHGENPVSCPELVQ

MED1

126

Q15648
QHRGEHAPELVLEPD

LRRN4

456

Q8WUT4
HQEINHFLCDVPPVL

OR10Q1

176

Q8NGQ4
FNLIPPVCEQAEHHL

KCNAB3

246

O43448
DALCTPHSHDPRDLQ

GARIN2

16

Q8N9W8
HELGHFNIPTLCDPA

TCAIM

381

Q8N3R3
AVEHAENPCHKEEPR

TBC1D31

981

Q96DN5
EDEHPQCLNSQPHAR

LILRB1

161

Q8NHL6
PAHCHLFLQPQGEDL

RECQL4

811

O94761
PRCRGCLAHGEEHPE

KCP

956

Q6ZWJ8
HIPLGELAAHCVRPC

KCP

1506

Q6ZWJ8
VDPVHGVHLPQAAAC

EPPK1

1366

P58107
EGRSEPHHLCDPQKT

PKD1L3

771

Q7Z443
PHHLCDPQKTVFERG

PKD1L3

776

Q7Z443
GRPIHCQVPGIDHFL

TENM1

1401

Q9UKZ4
LIQEGPFFVLCPDHH

SH3TC1

206

Q8TE82
EGCHDARPAAKPTVH

PPP1R26

76

Q5T8A7
REDHCHPQPLSAELI

PPP1R15B

261

Q5SWA1
CPLPENITHILVHGD

SVEP1

3181

Q4LDE5
GHHLLECPDELIERT

RDH10

151

Q8IZV5
ICHVPPETRQSEHPE

PLA2R1

1231

Q13018
VHVAVEHQLPPASRC

SOAT2

216

O75908
RCGHGEEQKLELNPH

TET1

676

Q8NFU7
GHDPEPGRLLCQAQH

ACOT4

111

Q8N9L9
VTLPCHHQLGLPEKD

CLMP

31

Q9H6B4
QAHLSEDCPDVPALH

CLUL1

326

Q15846
IDCHAPIGGIDHKPR

RNF213

4526

Q63HN8
CHELLGHVPLLAEPS

TPH1

271

P17752
DHPCLQAPELDEHLV

USP17L3

411

A6NCW0
DVPPQRLDGHCHSEL

TNFAIP2

346

Q03169
HGQNECDIPTQLPVH

UNC80

2001

Q8N2C7
DHPCLQVPELDEHLV

USP17L4

411

A6NCW7
SDHHEPICKPGLELN

SSH2

466

Q76I76
CNVDGRHPHDIIDDI

RPL12

141

P30050
PGNEHKIVPEALLCH

GTF2A1L

221

Q9UNN4
SPDLEAHEHPLPCDQ

TECPR1

746

Q7Z6L1
HQRIHTGEKPFACPE

ZNF672

301

Q499Z4
QHHDDILCAAFLPPQ

WDR49

281

Q8IV35
DHPCLQAPELDEHLV

USP17L18

411

D6R9N7
RCHFIHNPSEDLAAP

ZFP36

161

P26651
DHPCLQAPELDEHLV

USP17L5

411

A8MUK1
DHPCLQAPELDEHLV

USP17L21

411

D6R901
DHPCLQAPELDEHLV

USP17L13

411

C9JLJ4
DHPCLQAPELDEHLV

USP17L19

411

D6RCP7
EALHEQGVLCRDLHP

RPS6KL1

401

Q9Y6S9
NDDRDPPQHHSCLPD

USF3

1056

Q68DE3
PHSHGEEAVAQDRIP

TACC2

1581

O95359
LSRRDLPAHLQHDCP

TRAF4

121

Q9BUZ4
VPQGHCEEHLDPLSI

TRIM72

81

Q6ZMU5
DHPCLQAPELDEHLV

USP17L1

411

Q7RTZ2
PGPAHTARLEDAHDL

TET3

186

O43151
TCHELLGHVPLLADP

TPH2

316

Q8IWU9
APVNSIHPECRFHLE

VIPR2

16

P41587
PGLQKQDLCQEHHEP

TRIM17

91

Q9Y577
LARHCQLEPDHEGVP

TNPO3

376

Q9Y5L0
DHPCLQAPELDEHLV

USP17L12

411

C9JPN9
HQRLHTGERPFQCPE

ZNF786

611

Q8N393
ELSDLPGECRAHGHL

TTC28

786

Q96AY4
HCDRALEILLHPSEP

VWA5B2

261

Q8N398
DHPCLQAPELDEHLV

USP17L24

411

Q0WX57
DHPCLQVPELDEHLV

USP17L7

411

P0C7H9
DHPCLQVPELDEHLV

USP17L8

411

P0C7I0
VFHEDCHIPPVEAER

SP140

711

Q13342
EHAHPEDPECVLPQE

WDR24

556

Q96S15
TEDHSHLQEPALCGP

VEGFD

246

O43915
DHPCLQAPELDEHLV

USP17L22

411

D6RA61
DPHCHLQLEAPQLDV

VSIG10L2

491

P0DP72
DHPCLQAPELDEHLV

USP17L15

411

C9J2P7
DHPCLQAPELDEHLV

USP17L17

411

D6RBQ6
EDIHRPVLGEPEIHQ

ZNF202

336

O95125
HQRIHSGEEPHKCPE

ZNF449

341

Q6P9G9
DHPCLQAPELDEHLV

USP17L20

411

D6RJB6
DHPCLQAPELDEHLV

USP17L10

411

C9JJH3
VVENQLPHCLPAHDS

ZMAT1

461

Q5H9K5
DHPCLQAPELDEHLV

USP17L11

411

C9JVI0
CLPIPLDAGSHVADH

UNC79

2436

Q9P2D8