Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionopsonin binding

CR1 CR1L C4A C4B

4.40e-05251604GO:0001846
GeneOntologyMolecularFunctioncomplement component C3b receptor activity

CR1 CR1L

6.38e-0521602GO:0004877
GeneOntologyMolecularFunctioncomplement component C4b receptor activity

CR1 CR1L

6.38e-0521602GO:0001861
GeneOntologyMolecularFunctioncomplement binding

CR1 CR1L C4A C4B

1.20e-04321604GO:0001848
GeneOntologyMolecularFunctioncomplement component C4b binding

CR1 CR1L

1.90e-0431602GO:0001855
DomainMab-21

MAB21L4 MAB21L2 MAB21L1 ITPRIPL1

2.26e-06121574PF03281
DomainMab-21

MAB21L4 MAB21L2 MAB21L1 ITPRIPL1

2.26e-06121574SM01265
DomainMab-21_dom

MAB21L4 MAB21L2 MAB21L1 ITPRIPL1

2.26e-06121574IPR024810
Domain-

LRRC8E MFHAS1 NLRX1 CHADL LRRK1 LRRC4C NRROS LGI4 LRRC14B LRRN3 NLRC5 LRRC73 TPBG

3.31e-06321157133.80.10.10
DomainL_dom-like

LRRC8E MFHAS1 NLRX1 CHADL LRRK1 LRRC4C NRROS LGI4 LRRC14B LRRN3 NLRC5 LRRC73 TPBG

4.19e-0632815713IPR032675
DomainLRR

LRRC8E MFHAS1 CHADL LRRK1 LRRC4C NRROS LGI4 LRRN3 NLRC5 TPBG

7.91e-0620115710PS51450
DomainLRR_1

LRRC8E MFHAS1 CHADL LRRK1 LRRC4C NRROS LGI4 LRRN3 NLRC5 TPBG

1.67e-0521915710PF00560
DomainLeu-rich_rpt

LRRC8E MFHAS1 NLRX1 CHADL LRRK1 LRRC4C NRROS LGI4 LRRN3 NLRC5 TPBG

1.89e-0527115711IPR001611
DomainLRR_TYP

LRRC8E MFHAS1 CHADL LRRK1 LRRC4C NRROS LGI4 LRRN3 TPBG

1.91e-051771579SM00369
DomainLeu-rich_rpt_typical-subtyp

LRRC8E MFHAS1 CHADL LRRK1 LRRC4C NRROS LGI4 LRRN3 TPBG

1.91e-051771579IPR003591
Domain14_3_3

YWHAH YWHAZ YWHAQ

1.99e-0571573SM00101
Domain1433_1

YWHAH YWHAZ YWHAQ

1.99e-0571573PS00796
Domain1433_2

YWHAH YWHAZ YWHAQ

1.99e-0571573PS00797
Domain14-3-3_domain

YWHAH YWHAZ YWHAQ

1.99e-0571573IPR023410
Domain14-3-3_CS

YWHAH YWHAZ YWHAQ

1.99e-0571573IPR023409
Domain14-3-3

YWHAH YWHAZ YWHAQ

1.99e-0571573PF00244
Domain14-3-3

YWHAH YWHAZ YWHAQ

3.16e-0581573IPR000308
DomainCell_morpho_N

FRYL FRY

7.02e-0521572IPR025614
DomainCell_Morphogen_C

FRYL FRY

7.02e-0521572IPR025481
DomainMOR2-PAG1_mid

FRYL FRY

7.02e-0521572IPR029473
DomainMOR2-PAG1_mid

FRYL FRY

7.02e-0521572PF14228
DomainMOR2-PAG1_C

FRYL FRY

7.02e-0521572PF14225
DomainMOR2-PAG1_N

FRYL FRY

7.02e-0521572PF14222
DomainLRR_8

LRRC8E MFHAS1 CHADL LRRC4C NRROS LGI4 LRRN3 TPBG

1.01e-041711578PF13855
DomainROC_dom

MFHAS1 LRRK1

4.17e-0441572IPR020859
DomainROC

MFHAS1 LRRK1

4.17e-0441572PS51424
DomainAnaphylatoxin_comp_syst

C4A C4B

6.91e-0451572IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

6.91e-0451572IPR001840
DomainMab-21-like_1/2

MAB21L2 MAB21L1

6.91e-0451572IPR020950
DomainCys-rich_flank_reg_C

CHADL LRRC4C LGI4 LRRN3 TPBG

9.74e-04901575IPR000483
DomainLRRCT

CHADL LRRC4C LGI4 LRRN3 TPBG

9.74e-04901575SM00082
DomainANATO

C4A C4B

1.43e-0371572SM00104
DomainANAPHYLATOXIN_2

C4A C4B

1.43e-0371572PS01178
DomainANAPHYLATOXIN_1

C4A C4B

1.43e-0371572PS01177
DomainANATO

C4A C4B

1.43e-0371572PF01821
DomainAnaphylatoxin/fibulin

C4A C4B

1.43e-0371572IPR000020
DomainMacrogloblnA2_thiol-ester-bond

C4A C4B

1.90e-0381572IPR019565
DomainThiol-ester_cl

C4A C4B

1.90e-0381572PF10569
DomainMacrogloblnA2_CS

C4A C4B

1.90e-0381572IPR019742
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

ITGB4 YWHAH YWHAZ PIK3CA YWHAQ

2.24e-05461055M239
PathwayREACTOME_ACTIVATION_OF_BAD_AND_TRANSLOCATION_TO_MITOCHONDRIA

YWHAH YWHAZ YWHAQ

8.41e-05121053MM14482
PathwayREACTOME_SARS_COV_2_TARGETS_HOST_INTRACELLULAR_SIGNALLING_AND_REGULATORY_PATHWAYS

YWHAH YWHAZ YWHAQ

8.41e-05121053M45022
PathwayREACTOME_CHK1_CHK2_CDS1_MEDIATED_INACTIVATION_OF_CYCLIN_B_CDK1_COMPLEX

YWHAH YWHAZ YWHAQ

8.41e-05121053MM15443
PathwayKEGG_MEDICUS_PATHOGEN_HCV_CORE_TO_ERK_SIGNALING_PATHWAY

YWHAH YWHAZ YWHAQ

1.09e-04131053M47589
PathwayREACTOME_CHK1_CHK2_CDS1_MEDIATED_INACTIVATION_OF_CYCLIN_B_CDK1_COMPLEX

YWHAH YWHAZ YWHAQ

1.09e-04131053M27708
PathwaySIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES

PAK6 YWHAH YWHAZ PIK3CA YWHAQ

1.39e-04671055M295
PathwayPID_PI3K_PLC_TRK_PATHWAY

YWHAH YWHAZ PIK3CA YWHAQ

1.42e-04361054M271
PathwayREACTOME_ACTIVATION_OF_BAD_AND_TRANSLOCATION_TO_MITOCHONDRIA

YWHAH YWHAZ YWHAQ

1.71e-04151053M26902
PathwayREACTOME_SARS_COV_1_TARGETS_HOST_INTRACELLULAR_SIGNALLING_AND_REGULATORY_PATHWAYS

YWHAH YWHAZ YWHAQ

2.10e-04161053M46428
PathwayWP_CONGENITAL_GENERALIZED_LIPODYSTROPHY

ITGB4 LPIN3 PIK3CA

3.02e-04181053M42546
PathwayREACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS

YWHAH YWHAZ YWHAQ

3.02e-04181053MM14510
PathwayREACTOME_TP53_REGULATES_METABOLIC_GENES

YWHAH YWHAZ COX8C TNRC6A YWHAQ

4.03e-04841055M27495
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

LRRC8E SPOUT1 MFHAS1 POLE NLRX1 FBRSL1 PER1 ELP6 PFAS FRYL LRRK1 PLXND1 NPHP4 CNTROB ITGB4 RYR1 C6orf132 LPIN3 RADIL SH3PXD2B MDN1 MROH1 CSPG4 NLRC5 SDHA AHNAK2

2.66e-1111051682635748872
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

HDAC4 RALGAPB NELFB APBB1 FRYL PAK6 YWHAH YWHAZ C6orf132 LPIN3 ARFGEF3 LIMK1 RADIL SH3PXD2B MDN1 PRRC2C ARHGEF1 SEC24B YWHAQ AHNAK2

7.82e-098611682036931259
Pubmed

Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway.

CR1 CR1L C4A C4B

3.62e-088168414670299
Pubmed

Duplication and divergence of the amino-terminal coding region of the complement receptor 1 (CR1) gene. An example of concerted (horizontal) evolution within a gene.

CR1 CR1L C4B

1.11e-07316832295627
Pubmed

Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.

CR1 CR1L C4A C4B

1.69e-0711168423204401
Pubmed

Deficiency of decay-accelerating factor and complement receptor 1-related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg.

CR1 CR1L C4A C4B

2.52e-0712168418524992
Pubmed

The MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocyte migration.

ITGB4 YWHAH YWHAZ YWHAQ

5.06e-0714168412919677
Pubmed

Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome.

PFAS YWHAH YWHAZ NUP205 YWHAQ BAG6

9.08e-0767168629357390
Pubmed

The Cdk-like protein PCTAIRE-1 from mouse brain associates with p11 and 14-3-3 proteins.

YWHAH YWHAZ YWHAQ

1.10e-06516839197417
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

POLE ADNP2 ZNF217 BCL11A GPATCH8 CDT1 BAG6

1.62e-06116168730804394
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

HDAC4 RALGAPB NELFB FRYL CNTROB YWHAH YWHAZ RADIL FAM193A TNRC6A YWHAQ ANAPC5

1.99e-064461681224255178
Pubmed

PP2A regulates HDAC4 nuclear import.

HDAC4 YWHAH YWHAQ

2.19e-066168318045992
Pubmed

14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport.

YWHAH YWHAZ YWHAQ

2.19e-066168311864996
Pubmed

Specific interaction between 14-3-3 isoforms and the human CDC25B phosphatase.

YWHAH YWHAZ YWHAQ

2.19e-066168310713667
Pubmed

An evolutionarily conserved nested gene pair - Mab21 and Lrba/Nbea in metazoan.

NBEA MAB21L2 MAB21L1

2.19e-066168319482073
Pubmed

The interaction between casein kinase Ialpha and 14-3-3 is phosphorylation dependent.

YWHAH YWHAZ YWHAQ

2.19e-066168319860830
Pubmed

Constitutive expression of TNF-alpha and -beta genes in mouse embryo: roles of cytokines as regulator and effector on development.

CR1 CR1L C4A C4B

2.95e-062116848138038
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

LRRC8E ZC3H14 SPOUT1 POLE CNTROB NUP205 ZSCAN10 PRRC2C TNRC6A CDT1 YWHAQ BAG6

3.33e-064691681227634302
Pubmed

Phosphorylation-dependent association of the Ras-related GTP-binding protein Rem with 14-3-3 proteins.

YWHAH YWHAZ YWHAQ

3.82e-067168310441394
Pubmed

Interaction of apoptosis signal-regulating kinase 1 with isoforms of 14-3-3 proteins.

YWHAH YWHAZ YWHAQ

3.82e-067168315023544
Pubmed

14-3-3 isotypes facilitate coupling of protein kinase C-zeta to Raf-1: negative regulation by 14-3-3 phosphorylation.

YWHAH YWHAZ YWHAQ

3.82e-067168310620507
Pubmed

Cytosolic sequestration of spatacsin by Protein Kinase A and 14-3-3 proteins.

YWHAH YWHAZ YWHAQ

3.82e-067168336096339
Pubmed

Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation.

YWHAH YWHAZ YWHAQ

3.82e-067168327030597
Pubmed

Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain.

PAK6 YWHAZ LIMK1

3.82e-067168326375402
Pubmed

The expression of seven 14-3-3 isoforms in human meningioma.

YWHAH YWHAZ YWHAQ

3.82e-067168320388496
Pubmed

cAMP-elevation mediated by β-adrenergic stimulation inhibits salt-inducible kinase (SIK) 3 activity in adipocytes.

YWHAH YWHAZ YWHAQ

3.82e-067168322588126
Pubmed

A nonphosphorylated 14-3-3 binding motif on exoenzyme S that is functional in vivo.

YWHAH YWHAZ YWHAQ

3.82e-067168312383250
Pubmed

Efficient ADAM22 surface expression is mediated by phosphorylation-dependent interaction with 14-3-3 protein family members.

YWHAH YWHAZ YWHAQ

3.82e-067168316868027
Pubmed

Differential Subcellular Distribution and Translocation of Seven 14-3-3 Isoforms in Response to EGF and During the Cell Cycle.

YWHAH YWHAZ YWHAQ

3.82e-067168331906564
Pubmed

Phosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's disease.

YWHAH YWHAZ YWHAQ

3.82e-067168321390248
Pubmed

A human MAP kinase interactome.

HDAC4 ADNP2 PAK6 MIDEAS ITGB4 YWHAH YWHAZ ARHGEF1 TNRC6A C4A YWHAQ MGA

4.78e-064861681220936779
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RTEL1 NELFB PER1 RNF213 PFAS GPAM NPHP4 RADIL ZBTB39 TTC39A KLHDC10 MGA

5.53e-064931681215368895
Pubmed

Vpr protein of human immunodeficiency virus type 1 binds to 14-3-3 proteins and facilitates complex formation with Cdc25C: implications for cell cycle arrest.

YWHAH YWHAZ YWHAQ

6.09e-068168315708996
Pubmed

Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins.

YWHAH YWHAZ YWHAQ

6.09e-06816839524113
Pubmed

Identification of signalling proteins interacting with B-Raf in the yeast two-hybrid system.

YWHAH YWHAZ YWHAQ

6.09e-06816838668348
Pubmed

BCR kinase phosphorylates 14-3-3 Tau on residue 233.

YWHAH YWHAZ YWHAQ

6.09e-068168316045749
Pubmed

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2.

YWHAH YWHAZ YWHAQ

6.09e-068168323075850
Pubmed

Fibroblast growth factor receptor 2 phosphorylation on serine 779 couples to 14-3-3 and regulates cell survival and proliferation.

YWHAH YWHAZ YWHAQ

6.09e-068168318332103
Pubmed

14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteins.

YWHAH YWHAZ YWHAQ

6.09e-068168323622247
Pubmed

Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways.

LRRK1 PAK6 YWHAZ YWHAQ

6.14e-0625168424947832
Pubmed

Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin.

YWHAZ LIMK1 YWHAQ

9.10e-069168315660133
Pubmed

MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage.

YWHAH YWHAZ YWHAQ

9.10e-069168316888623
Pubmed

14-3-3 interacts with the tumor suppressor tuberin at Akt phosphorylation site(s).

YWHAH YWHAZ YWHAQ

9.10e-069168312438239
Pubmed

Identification and characterization of the interaction between tuberin and 14-3-3zeta.

YWHAH YWHAZ YWHAQ

9.10e-069168312176984
Pubmed

Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3.

YWHAH YWHAZ YWHAQ

9.10e-069168316511560
Pubmed

Kank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signaling.

YWHAH YWHAZ YWHAQ

9.10e-069168318458160
Pubmed

14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains.

YWHAH YWHAZ YWHAQ

9.10e-069168334294877
Pubmed

Subcellular targeting of p33ING1b by phosphorylation-dependent 14-3-3 binding regulates p21WAF1 expression.

YWHAH YWHAZ YWHAQ

9.10e-069168316581770
Pubmed

A novel heterodimerization domain, CRM1, and 14-3-3 control subcellular localization of the MondoA-Mlx heterocomplex.

YWHAH YWHAZ YWHAQ

9.10e-069168312446771
Pubmed

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.

YWHAH YWHAZ RADIL SH3PXD2B PIK3CA YWHAQ

1.13e-05103168621706016
Pubmed

Protein phosphatase 1 binds to phospho-Ser-1394 of the macrophage-stimulating protein receptor.

YWHAH YWHAZ YWHAQ

1.30e-0510168314505491
Pubmed

SLy2 targets the nuclear SAP30/HDAC1 complex.

YWHAH YWHAZ YWHAQ

1.30e-0510168320478393
Pubmed

Involvement of protein kinase PKN1 in G2/M delay caused by arsenite.

YWHAH YWHAZ YWHAQ

1.30e-0510168315791647
Pubmed

Interaction with 14-3-3 proteins promotes functional expression of the potassium channels TASK-1 and TASK-3.

YWHAH YWHAZ YWHAQ

1.30e-0510168312433946
Pubmed

14-3-3 proteins play a role in the cell cycle by shielding cdt2 from ubiquitin-mediated degradation.

YWHAH YWHAZ YWHAQ

1.30e-0510168325154416
Pubmed

Functional conservation of 14-3-3 isoforms in inhibiting bad-induced apoptosis.

YWHAH YWHAZ YWHAQ

1.30e-0510168311697890
Pubmed

JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage.

YWHAH YWHAZ YWHAQ

1.78e-0511168315696159
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TLCD1 SPOUT1 ABHD2 FRYL GPATCH8 CPT2 ITGB4 YWHAZ MEST SH3PXD2B ZSCAN10 FARP1 ARHGEF1 ADAMTS18 YWHAQ KLHDC10 MGA

2.18e-0510841681711544199
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

2.32e-052168222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

2.32e-052168216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

2.32e-052168215998580
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

2.32e-052168219062096
Pubmed

Functional identification of transcription control sequences of the mouse Crry gene.

CR1 CR1L

2.32e-05216828335915
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

2.32e-052168219933335
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

2.32e-05216822459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

2.32e-052168217645767
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

2.32e-052168212207352
Pubmed

Crry/p65, a membrane complement regulatory protein, has costimulatory properties on mouse T cells.

CR1 CR1L

2.32e-052168210779754
Pubmed

Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion.

CR1 CR1L

2.32e-052168216444293
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

2.32e-052168227758680
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

2.32e-052168222387014
Pubmed

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

C4A C4B

2.32e-052168223749435
Pubmed

Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.

C4A C4B

2.32e-052168223918728
Pubmed

Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Crry, the two genetic homologues of human CR1.

CR1 CR1L

2.32e-05216821730912
Pubmed

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.

C4A C4B

2.32e-05216823037333
Pubmed

Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.

C4A C4B

2.32e-052168211726230
Pubmed

Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.

C4A C4B

2.32e-05216824216347
Pubmed

Sequence determination of the thiolester site of the fourth component of human complement.

C4A C4B

2.32e-05216826950384
Pubmed

Mesangial cell complement receptor 1-related protein y limits complement-dependent neutrophil accumulation in immune complex glomerulonephritis.

CR1 CR1L

2.32e-052168219740350
Pubmed

Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.

C4A C4B

2.32e-05216828660986
Pubmed

Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.

C4A C4B

2.32e-05216828428773
Pubmed

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

C4A C4B

2.32e-052168224638111
Pubmed

Transcriptional repression of C4 complement by hepatitis C virus proteins.

C4A C4B

2.32e-052168221345967
Pubmed

Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

C4A C4B

2.32e-05216822572548
Pubmed

The complement component C4 of mammals.

C4A C4B

2.32e-05216822302180
Pubmed

Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.

C4A C4B

2.32e-052168222151770
Pubmed

C4d-positive chronic rejection: a frequent entity with a poor outcome.

C4A C4B

2.32e-052168218091514
Pubmed

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.

C4A C4B

2.32e-052168229080553
Pubmed

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.

C4A C4B

2.32e-05216826589636
Pubmed

C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.

C4A C4B

2.32e-052168225339671
Pubmed

A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.

C4A C4B

2.32e-052168217728371
Pubmed

Structure and organization of the C4 genes.

C4A C4B

2.32e-05216826149580
Pubmed

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.

C4A C4B

2.32e-05216826149581
Pubmed

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

C4A C4B

2.32e-052168212115608
Pubmed

Biochemistry and biology of anaphylatoxins.

C4A C4B

2.32e-05216823542363
Pubmed

C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.

C4A C4B

2.32e-05216822387317
Pubmed

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.

C4A C4B

2.32e-052168216908004
Pubmed

Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.

C4A C4B

2.32e-05216827365238
Pubmed

Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.

STRC STRCP1

2.32e-052168234910522
Pubmed

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.

C4A C4B

2.32e-05216827391573
InteractionTOP3B interactions

LRRC8E HDAC4 SPOUT1 RTEL1 MFHAS1 POLE NLRX1 FBRSL1 PER1 ELP6 PFAS FRYL LRRK1 PLXND1 NPHP4 CNTROB ITGB4 RYR1 C6orf132 LPIN3 RADIL SH3PXD2B MDN1 MROH1 CSPG4 SEC24B NLRC5 SDHA AHNAK2

3.91e-06147015929int:TOP3B
InteractionFRYL interactions

FRYL YWHAH YWHAZ FRY TRIM67 YWHAQ

6.33e-06581596int:FRYL
InteractionPFKFB2 interactions

SH2D3A NPHP4 YWHAH YWHAZ TRIM67 YWHAQ

9.36e-06621596int:PFKFB2
InteractionLIMK1 interactions

RTEL1 MFHAS1 PAK6 YWHAZ LIMK1 SH3PXD2B TRIM67

1.18e-05971597int:LIMK1
InteractionFBXO38 interactions

POLE SOX30 ADNP2 ZNF217 BCL11A GPATCH8 CDT1 BAG6

2.01e-051451598int:FBXO38
InteractionSTOX2 interactions

PER1 YWHAH YWHAZ YWHAQ

2.01e-05211594int:STOX2
InteractionPAK6 interactions

LRRK1 PAK6 YWHAH YWHAZ LIMK1 YWHAQ

2.41e-05731596int:PAK6
InteractionATAT1 interactions

YWHAH YWHAZ TRIM67 YWHAQ

2.44e-05221594int:ATAT1
InteractionCR1 interactions

CR1 CR1L C4A

2.62e-0581593int:CR1
InteractionKCNK15 interactions

YWHAH YWHAZ YWHAQ

2.62e-0581593int:KCNK15
InteractionUAP1 interactions

YWHAH YWHAZ TRIM67 YWHAQ BAG6

2.72e-05451595int:UAP1
InteractionPACS2 interactions

YWHAH YWHAZ TRIM67 YWHAQ

3.51e-05241594int:PACS2
InteractionPSD3 interactions

HDAC4 LRRC4C YWHAH YWHAZ TRIM67 YWHAQ

3.53e-05781596int:PSD3
InteractionRTKN interactions

TLCD3B HDAC4 MFHAS1 YWHAH YWHAZ LPIN3 YWHAQ

3.58e-051151597int:RTKN
InteractionHCST interactions

LRRC8E TCAF2 RTEL1 NLRX1 NELFB RNF213 RADIL MDN1 ITPRIPL1

3.73e-052051599int:HCST
InteractionKCNK9 interactions

YWHAH YWHAZ YWHAQ

3.91e-0591593int:KCNK9
InteractionC6orf132 interactions

YWHAH YWHAZ C6orf132 YWHAQ

4.15e-05251594int:C6orf132
InteractionPLEKHM3 interactions

YWHAH YWHAZ YWHAQ MGAT5B

4.87e-05261594int:PLEKHM3
InteractionOSBPL6 interactions

HDAC4 YWHAH YWHAZ LPIN3 TRIM67 YWHAQ

5.37e-05841596int:OSBPL6
InteractionOTOG interactions

YWHAH YWHAZ YWHAQ

5.55e-05101593int:OTOG
InteractionSPIRE1 interactions

YWHAH YWHAZ TRIM67 YWHAQ

5.68e-05271594int:SPIRE1
InteractionGPBP1L1 interactions

MFHAS1 LRRK1 YWHAH YWHAZ SH3PXD2B TNRC6A

6.13e-05861596int:GPBP1L1
InteractionKIAA0930 interactions

FRYL YWHAH YWHAZ YWHAQ

6.59e-05281594int:KIAA0930
InteractionPLEKHA3 interactions

YWHAH YWHAZ SEC24B YWHAQ

6.59e-05281594int:PLEKHA3
InteractionRALGPS2 interactions

HDAC4 YWHAH YWHAZ LPIN3 YWHAQ

6.64e-05541595int:RALGPS2
InteractionKLC2 interactions

TRAPPC11 MAB21L2 YWHAH YWHAZ TRIM67 ARHGEF1 ARMC5 YWHAQ

6.79e-051721598int:KLC2
InteractionMAP3K4 interactions

DNAJC13 MFHAS1 CNTROB YWHAZ TRIM67 BAG6

6.97e-05881596int:MAP3K4
InteractionTANC2 interactions

HDAC4 YWHAH YWHAZ LPIN3 TRIM67 YWHAQ

7.43e-05891596int:TANC2
InteractionR3HDM2 interactions

YWHAH YWHAZ PRRC2C SEC24B TNRC6A YWHAQ MGAT5B

7.45e-051291597int:R3HDM2
InteractionCDCA7 interactions

YWHAH YWHAZ YWHAQ

7.59e-05111593int:CDCA7
InteractionSPEG interactions

NLRX1 YWHAH YWHAZ YWHAQ

7.60e-05291594int:SPEG
InteractionFAM13A interactions

RTEL1 YWHAH YWHAZ YWHAQ

7.60e-05291594int:FAM13A
InteractionGIGYF1 interactions

HDAC4 CNTROB YWHAH YWHAZ LPIN3 TNRC6A YWHAQ KLHDC10

8.30e-051771598int:GIGYF1
InteractionBAG5 interactions

LRRC8E DNAJC13 DHRS13 RNF213 LRRK1 YWHAZ TRIM67 POLR3E PRRC2C RPS6KL1 SDHA

8.63e-0534115911int:BAG5
InteractionALS2 interactions

YWHAH YWHAZ TRIM67 YWHAQ

9.94e-05311594int:ALS2
InteractionPPP1R3E interactions

YWHAH YWHAZ YWHAQ

1.01e-04121593int:PPP1R3E
InteractionREM1 interactions

YWHAH YWHAZ YWHAQ

1.01e-04121593int:REM1
InteractionUACA interactions

RNF213 MAB21L2 YWHAH YWHAZ TRIM67 YWHAQ BAG6

1.04e-041361597int:UACA
InteractionTRAPPC2 interactions

TRAPPC11 MFHAS1 YWHAH YWHAZ OPRL1 SEC24B YWHAQ

1.04e-041361597int:TRAPPC2
InteractionTRAPPC11 interactions

TRAPPC11 YWHAH YWHAZ TRIM67 SEC24B YWHAQ

1.13e-04961596int:TRAPPC11
InteractionUVRAG interactions

NLRX1 YWHAH YWHAZ POLR3E TGFBRAP1 YWHAQ

1.20e-04971596int:UVRAG
InteractionYWHAG interactions

ATP6V1A TRAPPC11 HDAC4 RALGAPB SH2D3A NELFB APBB1 FRYL MAB21L2 PAK6 YWHAH YWHAZ C6orf132 LPIN3 RADIL MDN1 TRIM67 PRRC2C ARHGEF1 SEC24B YWHAQ SDHA AHNAK2

1.25e-04124815923int:YWHAG
InteractionSH3BP5L interactions

YWHAH YWHAZ TRIM67 YWHAQ

1.28e-04331594int:SH3BP5L
InteractionKCNK3 interactions

YWHAH YWHAZ YWHAQ

1.30e-04131593int:KCNK3
InteractionARL8A interactions

DNAJC13 LRRC4C YWHAH YWHAZ TRIM67 YWHAQ

1.34e-04991596int:ARL8A
InteractionPPIP5K2 interactions

YWHAH YWHAZ TRIM67 SEC24B YWHAQ

1.39e-04631595int:PPIP5K2
InteractionREEP3 interactions

YWHAH YWHAZ YWHAQ BAG6

1.44e-04341594int:REEP3
InteractionYWHAH interactions

ZC3H14 TRAPPC11 HDAC4 RALGAPB NELFB APBB1 FRYL PAK6 YWHAH YWHAZ C6orf132 LPIN3 ARFGEF3 RADIL SH3PXD2B TRIM67 PIK3CA PRRC2C SEC24B YWHAQ AHNAK2

1.60e-04110215921int:YWHAH
InteractionSMTNL2 interactions

MFHAS1 YWHAH YWHAZ YWHAQ

1.61e-04351594int:SMTNL2
InteractionFAM86C1P interactions

YWHAH YWHAZ ZBTB39 YWHAQ

1.61e-04351594int:FAM86C1P
InteractionGCKR interactions

DNHD1 YWHAZ YWHAQ

1.65e-04141593int:GCKR
InteractionEML3 interactions

NPHP4 YWHAH YWHAZ TRIM67 YWHAQ

1.74e-04661595int:EML3
InteractionLATS1 interactions

NPHP4 CNTROB YWHAH YWHAZ LIMK1 FAM193A MDN1 SEC24B TNRC6A YWHAQ FHL1 MGA

2.00e-0444015912int:LATS1
InteractionPANK2 interactions

YWHAH YWHAZ TRIM67 YWHAQ

2.01e-04371594int:PANK2
InteractionTTC28 interactions

RAMP2 PAK6 YWHAH YWHAZ TRIM67 YWHAQ

2.16e-041081596int:TTC28
InteractionPFKFB4 interactions

YWHAH YWHAZ TRIM67 YWHAQ

2.23e-04381594int:PFKFB4
InteractionRIPK4 interactions

ANK2 RTEL1 POLE PFAS YWHAH YWHAZ MDN1 FARP1 ARMC5 YWHAQ BAG6 SDHA

2.26e-0444615912int:RIPK4
InteractionFRY interactions

HDAC4 FRYL FRY

2.50e-04161593int:FRY
InteractionSAMSN1 interactions

YWHAH YWHAZ YWHAQ

2.50e-04161593int:SAMSN1
InteractionKANK1 interactions

YWHAH YWHAZ TRIM67 YWHAQ

2.73e-04401594int:KANK1
InteractionZFP36L2 interactions

TLCD3B POLR2G YWHAH YWHAZ TRIM67 YWHAQ MGA MAB21L1

2.77e-042111598int:ZFP36L2
InteractionLPIN3 interactions

HDAC4 YWHAH YWHAZ LPIN3 YWHAQ

2.80e-04731595int:LPIN3
InteractionPIK3C3 interactions

NLRX1 YWHAH YWHAZ TRIM67 TGFBRAP1 YWHAQ

2.90e-041141596int:PIK3C3
InteractionINPP5F interactions

YWHAH YWHAZ TRIM67 YWHAQ

3.01e-04411594int:INPP5F
InteractionZNF395 interactions

YWHAH YWHAZ YWHAQ

3.02e-04171593int:ZNF395
InteractionPIPOX interactions

ELP6 ZNF217 TRIM67

3.02e-04171593int:PIPOX
InteractionDCPS interactions

DNAJC13 SPOUT1 HMX3 POLR2G PFAS C6orf132 NUP205 MDN1 TRIM67 YWHAQ BARX1

3.03e-0439415911int:DCPS
InteractionNELFB interactions

NELFB ELP6 YWHAH YWHAZ TRIM67 YWHAQ

3.04e-041151596int:NELFB
InteractionTPD52L1 interactions

PAK6 YWHAH YWHAZ YWHAQ

3.31e-04421594int:TPD52L1
InteractionSSH3 interactions

PFAS CPT2 YWHAZ NUP205 LIMK1

3.38e-04761595int:SSH3
InteractionDCP1A interactions

HDAC4 CNTROB YWHAH YWHAZ TRIM67 TNRC6A YWHAQ

3.54e-041661597int:DCP1A
InteractionFAM53B interactions

YWHAH YWHAZ YWHAQ

3.60e-04181593int:FAM53B
InteractionSYDE2 interactions

APBB1 YWHAH YWHAZ YWHAQ

3.62e-04431594int:SYDE2
InteractionSSH2 interactions

YWHAH YWHAZ LIMK1 YWHAQ

3.62e-04431594int:SSH2
InteractionPPFIBP2 interactions

YWHAH YWHAZ TRIM67 YWHAQ

3.62e-04431594int:PPFIBP2
InteractionGARRE1 interactions

CNTROB YWHAH YWHAZ FAM193A SEC24B TNRC6A YWHAQ

3.67e-041671597int:GARRE1
InteractionARL6IP6 interactions

LRRC8E TRAPPC11 YWHAH YWHAZ YWHAQ

3.81e-04781595int:ARL6IP6
InteractionARL3 interactions

PLXND1 YWHAH YWHAZ TRIM67 YWHAQ

3.81e-04781595int:ARL3
InteractionPAK4 interactions

LRRK1 PAK6 YWHAH YWHAZ LIMK1 TRIM67 YWHAQ

3.95e-041691597int:PAK4
InteractionSAMD4A interactions

YWHAH YWHAZ TRIM67 YWHAQ

3.96e-04441594int:SAMD4A
InteractionSIK3 interactions

NPHP4 YWHAH YWHAZ TRIM67 YWHAQ

4.04e-04791595int:SIK3
InteractionSAMD4B interactions

LRRC8E YWHAH YWHAZ FAM193A TRIM67 YWHAQ

4.18e-041221596int:SAMD4B
InteractionNOTCH1 interactions

PTBP3 RBP3 APBB1 NBEA FRYL MDN1 TRIM67 PIK3CA HEY2 ANAPC5

4.25e-0434515910int:NOTCH1
InteractionFAM163A interactions

YWHAH YWHAZ YWHAQ

4.26e-04191593int:FAM163A
InteractionNADK interactions

HDAC4 YWHAH YWHAZ LPIN3 YWHAQ

4.28e-04801595int:NADK
InteractionRGS12 interactions

NBEA YWHAH YWHAZ YWHAQ

4.32e-04451594int:RGS12
InteractionPPM1H interactions

HDAC4 YWHAH YWHAZ LPIN3 TRIM67 YWHAQ

4.36e-041231596int:PPM1H
InteractionCDSN interactions

OR2L13 YWHAZ TRIM67 YWHAQ BAG6 ITPRIPL1

4.55e-041241596int:CDSN
InteractionCGNL1 interactions

YWHAH YWHAZ TRIM67 YWHAQ

4.70e-04461594int:CGNL1
InteractionPARP8 interactions

YWHAH YWHAZ YWHAQ

4.98e-04201593int:PARP8
InteractionMLXIP interactions

YWHAH YWHAZ YWHAQ

4.98e-04201593int:MLXIP
InteractionRASSF2 interactions

YWHAH YWHAZ TRIM67 YWHAQ

5.11e-04471594int:RASSF2
InteractionDCLK1 interactions

HDAC4 YWHAH YWHAZ LPIN3 TRIM67 YWHAQ

5.17e-041271596int:DCLK1
InteractionPPFIBP1 interactions

PSG11 MAB21L2 YWHAH YWHAZ TRIM67 PRRC2C YWHAQ

5.21e-041771597int:PPFIBP1
InteractionNEK1 interactions

MFHAS1 LRRK1 YWHAH YWHAZ YWHAQ

5.36e-04841595int:NEK1
InteractionSH3PXD2A interactions

HDAC4 YWHAH YWHAZ LPIN3 SH3PXD2B YWHAQ

5.39e-041281596int:SH3PXD2A
InteractionMTMR12 interactions

YWHAH YWHAZ TRIM67 YWHAQ

5.54e-04481594int:MTMR12
InteractionNHS interactions

YWHAH YWHAZ YWHAQ BAG6

5.54e-04481594int:NHS
InteractionSPATA13 interactions

YWHAH YWHAZ YWHAQ

5.77e-04211593int:SPATA13
InteractionSPIRE2 interactions

YWHAH YWHAZ YWHAQ

5.77e-04211593int:SPIRE2
Cytoband13q13

NBEA MAB21L1

1.34e-045169213q13
CytobandEnsembl 112 genes in cytogenetic band chr15q15

PAK6 CDAN1 STRC MGA STRCP1

2.23e-041471695chr15q15
GeneFamily14-3-3 phospho-serine/phospho-threonine binding proteins

YWHAH YWHAZ YWHAQ

6.55e-06710531053
GeneFamilyComplement system|Sushi domain containing

CR1 CR1L C4A C4B

5.48e-05361054492
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C4A C4B

1.17e-03910521234
GeneFamilyGlycosyltransferase family 6|Blood group antigens

CR1 C4A C4B

1.28e-03371053454
GeneFamilyTLC domain containing

TLCD3B TLCD1

1.46e-031010521374
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ANK2 NBEA LRRC4C ARFGEF3 LRRN3 RPS6KL1 MAB21L1

8.95e-071971698fd43fc1cbf0c17b370397d73dddc572565a759c7
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ANK2 NBEA ARFGEF3 LRRN3 BARX1 RPS6KL1 MAB21L1

9.30e-071981698dac7b68bb8f1c4d8aa7fdfada61f79956866e874
ToppCellCOVID-19-APC-like-Monocytes|COVID-19 / group, cell type (main and fine annotations)

TSPOAP1 FAM131A RYR1 RADIL LRRN3 PIK3CA SLC26A6

2.47e-061581697a0d94bd067424783863a48db20976d4c2043600c
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAB21L4 DHRS13 LRRC14B TRIM67 MROH1 AHNAK2

3.58e-061081696d620f07243c2628494e689bbfabc14c453f4b1f4
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD3B RAMP2 DACH1 PLXND1 LRRC4C SOX7 ZBTB39

8.02e-061891697ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ANK2 NBEA LRRN3 TRIM67 RPS6KL1 MAB21L1

1.05e-05197169727c044833e471a312a572e0b1c83e4bc8a36e896
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ANK2 NBEA ARFGEF3 TRIM67 RPS6KL1 MAB21L1

1.09e-05198169785881637641d8996be2edc65c4bceff0433135e7
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass

DNHD1 MFHAS1 APBB1 CHADL ME3 NUP205 RNF220

1.12e-051991697fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCellInfluenza-Influenza_Severe-Myeloid-cDC|Influenza_Severe / Disease, condition lineage and cell class

MFHAS1 NBEA BCL11A PAK6 HPDL ME3 MEST

1.16e-052001697b8415a68ad6f4fea562236a1b0da0dc376d874fb
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal|3m / Sample Type, Dataset, Time_group, and Cell type.

TLCD3B ANK2 NBEA BCL11A YWHAH YWHAQ RPS6KL1

1.16e-052001697af99d90070e2933fd2e9512590c6cf3bd6e15539
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PAK6 PEAK3 LGI4 HYAL3 CSPG4 CCDC157

2.93e-05156169660f1ce38e34b582f589db1e0d6139282c1902b2b
ToppCellfacs-Heart-RV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC4C LIMK1 MDN1 PLA2G4C CSPG4 HEY2

5.93e-0517716967c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCellfacs-Heart-RV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC4C LIMK1 MDN1 PLA2G4C CSPG4 HEY2

5.93e-051771696e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCellPND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSPOAP1 FAM131A ITGB4 YWHAH LRRN3 ABTB1

6.12e-05178169663f5880a5b514e20ef2c07a6a9cb8df34e6cede5
ToppCellPND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSPOAP1 FAM131A ITGB4 YWHAH LRRN3 ABTB1

6.12e-05178169682c84f8b8a7e6a3d3be3351b348a37143279c100
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAMP2 PLXND1 SOX7 ZSCAN10 CENPI CDT1

6.12e-051781696462111b61f37338f97ac7dc6c7da1d4316b54445
ToppCellPND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSPOAP1 FAM131A ITGB4 YWHAH LRRN3 ABTB1

6.12e-051781696cb91558469ae0748106fb0b6d702edb0ff21a884
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DACH1 NBEA PLXND1 HPDL RNF220 HYAL3

6.31e-051791696dd94ebe69ade6f51b94058abe066216f0de9feda
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

RAMP2 DACH1 RNF213 NRROS MEST SOX7

6.92e-0518216967af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCellE18.5-samps-Endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

RAMP2 DACH1 RNF213 NRROS MEST SOX7

6.92e-051821696e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCellwk_15-18-Epithelial-PNS-Early_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TLCD3B HMX3 LGI4 KIAA1755 MGAT5B MAB21L1

7.13e-0518316967e8366ec8117d36cec67f77dcb0e9a6032d87fcb
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-6_RORB_HPCA|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DACH1 LRRK1 LGI4 LRRN3 FHL1 TPBG

7.13e-051831696c7e94fe3e7669db9304b249979fef7a69c30a143
ToppCellMild/Remission-B_intermediate-10|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK2 TSPOAP1 LRRK1 NRROS YWHAH LRRC73

7.13e-051831696278064c9f0582463b83bf156d34e77f60187613b
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC4C LGI4 ITGB4 HYAL3 CSPG4 C4A

7.13e-0518316968330c39184ce076e1f95fd3725b68af551d89db0
ToppCell(4)_Endothelial_cells-(40)_EC-arterial|World / Cell class and subclass of bone marrow stroma cells in homeostatis

TLCD3B RAMP2 DACH1 ITGB4 SOX7 RPS6KL1

7.35e-0518416967e1a2971321ddcfa00d78d3e3ba7960e532f9392
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DHRS13 ELP6 PLXND1 NPEPL1 SEC24B MGA

7.57e-0518516967925519b855f76444a0b57382ce35d89457b0b14
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PSG11 YWHAH MEST BTG2 CSPG4 HEY2

8.03e-0518716966820bfbe552ea5e62cfe699687b051a17d9fda61
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ANK2 LRRN3 TRIM67 RPS6KL1 MAB21L1

8.27e-051881696bd091503f580dedab40e0996273101285d24b586
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-osteoclast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LRRC8E ATP6V1A ARFGEF3 SH3PXD2B CSPG4 AHNAK2

8.27e-051881696762b52f21d2bc5409f86746a904c4358490be9c0
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP2 ITGB4 ME3 MEST SOX7 ADAMTS18

9.02e-0519116960e8a73f01e3ec95d242c09231bcf3790324d0a67
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

RAMP2 DACH1 PLXND1 NRROS MEST SOX7

9.02e-05191169644c596984c6196f6014e0e405dbe5560841e54ff
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP2 ITGB4 ME3 MEST SOX7 ADAMTS18

9.02e-05191169654bbccc554f43ba2ebdf9ea191b94c8f16081b53
ToppCellE16.5-samps-Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

RAMP2 DACH1 PLXND1 NRROS MEST SOX7

9.02e-051911696e7521d4d24f016d4e531cd492a7a69604f0c9e6f
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHADL LRRC4C OPRL1 TRIM67 CSPG4 MGAT5B

9.02e-051911696ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHADL LRRC4C OPRL1 TRIM67 CSPG4 MGAT5B

9.02e-051911696478e8341ee03b05501e2233e02cef5f97492c95d
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ANK2 HMX3 TRIM67 BARX1 MAB21L1

9.29e-051921696307d64ef7add6a2778733e9945a1bd687feb6f44
ToppCellE15.5-Endothelial|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAMP2 DACH1 PLXND1 NRROS MEST SOX7

9.29e-05192169688cc7f14d031a0613d032eb01c93e88c72d3938f
ToppCellE15.5-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAMP2 DACH1 PLXND1 NRROS MEST SOX7

9.55e-0519316969f4ffce4e1440b009b0b5947ebf52b12a644704d
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ANK2 NBEA TRIM67 RPS6KL1 MAB21L1

9.55e-051931696a189d46c39067b717509cd144e0225cc93d7731d
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ANK2 ARFGEF3 TRIM67 RPS6KL1 MAB21L1

9.55e-0519316968851275bcf4ecd6e87a91c8784fc5d76d246ff3b
ToppCellE15.5-Endothelial-proliferative_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAMP2 DACH1 PLXND1 NRROS MEST SOX7

9.55e-051931696ed6fc4f731624be702563d7d2f0bf366bec1e042
ToppCellE15.5-Endothelial-capillary_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAMP2 DACH1 PLXND1 NRROS MEST SOX7

9.55e-0519316963b3ffba483d114e9036a6fc64895fc37fc19d3e5
ToppCellE15.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAMP2 DACH1 PLXND1 NRROS MEST SOX7

9.55e-0519316961719a741f8458f658e2965853020f485c22d6106
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Neuronal-Cortical_hem|1_mon / Sample Type, Dataset, Time_group, and Cell type.

ADAMTS3 LRRC4C MEST TRIM67 HEY2 TPBG

9.83e-0519416966f32422e1c079a2fbf0ab568e6cb8365fd627d9a
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ANK2 NBEA ARFGEF3 RPS6KL1 MAB21L1

1.01e-041951696b25c534fc6320d4da6437ef1b27e32a5d5256f3e
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAMP2 DACH1 SOX7 FRY PLA2G4C FHL1

1.04e-041961696a53caedd0103bd162b3aee8ab87b4442a5e0338f
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Deep_Layer|World / Primary Cells by Cluster

ATP6V1A ADAMTS3 BCL11A PLXND1 YWHAH MAB21L1

1.07e-04197169641e823b14697827f657b13adb3afa581bd91a9cb
ToppCellwk_08-11-Epithelial-PNS|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TLCD3B ANK2 HMX3 MAB21L2 LGI4 MAB21L1

1.07e-041971696ce3f9feb6935f0e9daf13673b0a0d6e92817e187
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ANK2 NBEA ARFGEF3 RPS6KL1 MAB21L1

1.07e-0419716968951787ed1f7ac1772a6ef0ba2dd44c51fd3c47b
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAMP2 PER1 PLXND1 PLA2G4C FARP1 BAG6

1.07e-041971696789c97ca9d1e28df3353140046047f11fbccc1d0
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ANK2 NBEA ARFGEF3 RPS6KL1 MAB21L1

1.10e-041981696b58138581f1a9073267d64c1211c5b9b4de71d3e
ToppCellwk_08-11-Epithelial-PNS-TM4SF4+_CHODL+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TLCD3B ANK2 HMX3 MAB21L2 RPS6KL1 MAB21L1

1.10e-041981696eb3c389e7452d74e5e15179503e480d6d11ca9ca
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-cortical_neurons_1|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

ADAMTS3 NBEA BCL11A PLXND1 ARFGEF3 RPS6KL1

1.10e-041981696d81f35c0066558ff96dd06f58fca72cd82e681e8
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ANK2 NBEA LRRN3 RPS6KL1 MAB21L1

1.10e-041981696800ade4261695f2efd869d2b1243571de963c431
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ANK2 NBEA LRRN3 RPS6KL1 MAB21L1

1.13e-041991696ce8dbfd969b3b9c08e1c57c2bfd899818e878731
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Neuronal|GW10 / Sample Type, Dataset, Time_group, and Cell type.

ATP6V1A APBB1 BCL11A YWHAZ LRRN3 RPS6KL1

1.13e-041991696b2508bf591720830e8e3494b1337aab14539956d
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

TLCD3B NBEA BCL11A YWHAH YWHAZ RPS6KL1

1.13e-0419916960cd3e4e0fba000c996feaf012ff32198e1048c9d
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

RAMP2 DACH1 RNF213 NRROS FRY PLA2G4C

1.16e-042001696bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ANK2 GPATCH8 CNTROB ARMC5 MAB21L1 SLC26A6

1.16e-04200169624e13b6d9d2d8b29df1f02544ea9c50084d9e75c
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Cortical_neuron|3m / Sample Type, Dataset, Time_group, and Cell type.

TLCD3B ANK2 NBEA BCL11A YWHAH RPS6KL1

1.16e-042001696c248233b004f8ef0bab3c65ecfe295887966f2ee
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Cortical_neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

ANK2 NBEA BCL11A MAB21L2 YWHAH MAB21L1

1.16e-04200169668c90376e2779434e4ad8dc6dd3b44baa700e2f4
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal|GW10 / Sample Type, Dataset, Time_group, and Cell type.

ATP6V1A APBB1 BCL11A YWHAZ LRRN3 RPS6KL1

1.16e-04200169604699d1149a143b96d6f292c0d70c4d3e6dfc611
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

RAMP2 DACH1 RNF213 NRROS FRY PLA2G4C

1.16e-042001696432384faeade8e609154fab3d96c955a8ec868dd
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ANK2 NBEA LGI4 LRRN3 MAB21L1

1.16e-042001696553e9612874480f4d2a45671462e266cd0a09321
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|367C / Donor, Lineage, Cell class and subclass (all cells)

CHADL HPDL RYR1 TGFBRAP1 CDT1

1.43e-041311695aeeb5718b3a7122492ad2659d5c8112f60839ff3
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

2.64e-0521522DOID:0110471 (implicated_via_orthology)
Diseaseprostate cancer, disease progression measurement

RBBP8NL RFNG MROH1

2.51e-04241523EFO_0008336, MONDO_0008315
Diseasepulse pressure measurement

RAMP2 ANK2 MFHAS1 FBRSL1 RNF213 NBEA FRYL GPATCH8 CR1L OPRL1 LIMK1 FAM193A TNRC6A LINC00208 KIAA1755 FHL1 BAG6 CCDC157

3.08e-04139215218EFO_0005763
Diseaseblood sedimentation

CR1 CR1L

5.44e-0471522EFO_0004304
Diseaseintellectual disability (implicated_via_orthology)

ZC3H14 ANK2 YWHAZ YWHAQ

6.19e-04751524DOID:1059 (implicated_via_orthology)
Diseasecortical surface area measurement, neuroimaging measurement

ADAMTS3 ACTRT2 FARP1 TNRC6A ADAMTS18 KIAA1755

1.18e-032271526EFO_0004346, EFO_0010736
Diseaseliver fat measurement

GPAM ZNF217 TGFBRAP1

1.42e-03431523EFO_0010821
DiseaseAdenoid Cystic Carcinoma

BCL11A ITGB4 PIK3CA MGA

1.81e-031001524C0010606
DiseaseWeight Gain

RAMP2 RFNG MEST PIK3CA

1.94e-031021524C0043094
Diseaseaortic measurement

MFHAS1 LIMK1 ELL2 LINC00208 ADAMTS18 FHL1

1.97e-032511526EFO_0020865
DiseaseIGFBP-1 measurement

ZNF217 TGFBRAP1

1.98e-03131522EFO_0005118
DiseaseAdenocarcinoma Of Esophagus

PIK3CA BARX1

2.30e-03141522C0279628
Diseaseapolipoprotein A 1 measurement, apolipoprotein B measurement

MIDEAS NPC1L1 NLRC5 ABCG8

2.32e-031071524EFO_0004614, EFO_0004615
Diseasesystemic lupus erythematosus

TRAPPC11 MFHAS1 FBRSL1 LRRK1 CPT2 SOX7 LIMK1 FAM193A LINC00208 C4B AHNAK2

2.94e-0379915211MONDO_0007915
Diseaseantihyperlipidemic drug use measurement

FBRSL1 OPRL1 NPC1L1 ABCG8

3.01e-031151524EFO_0803367
Diseasetriacylglycerol 50:5 measurement

LRRC8E DACH1

3.02e-03161522EFO_0010412
DiseaseBenign neoplasm of stomach

POLE PIK3CA

3.41e-03171522C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

POLE PIK3CA

3.41e-03171522C0496905
DiseaseCarcinoma in situ of stomach

POLE PIK3CA

3.41e-03171522C0154060
Diseasenon-high density lipoprotein cholesterol measurement

DNAJC13 ADAMTS3 ADNP2 FBRSL1 GPAM MIDEAS OPRL1 PROX2 NPC1L1 ABCG8

3.97e-0371315210EFO_0005689
DiseaseX-24309 measurement

DNAJC13 MIDEAS

4.71e-03201522EFO_0800872

Protein segments in the cluster

PeptideGeneStartEntry
QGRLLPAPSAHFLKH

LINC00208

11

Q96KT6
LHFPRLSPAALHNGL

FBRSL1

971

Q9HCM7
QPTHPIRLGLALNFS

YWHAQ

161

P27348
ALLQHVALQFEPGPL

ARHGEF1

61

Q92888
LIPFRPSIQFQGLHG

ELL2

51

O00472
LGLSLQVLEPPQHGA

CSPG4

1391

Q6UVK1
PLHAGQPHFLQSQLA

CSPG4

1766

Q6UVK1
RHLVPGAPFLLQALV

C4B

376

P0C0L5
QPTHPIRLGLALNFS

YWHAH

166

Q04917
LHGHFQPLQRLQPQL

BAG6

771

P46379
LHQAPEALFVPQQLG

ACTRT2

256

Q8TDY3
NHLGALPNIELTSPR

ABHD2

161

P08910
QRFHALAQPGLPGLV

CDT1

171

Q9H211
LRPGLQPFLLHFLLV

ABCG8

521

Q9H221
PAPDLHFLLDSGLQL

ARMC5

746

Q96C12
ALSLPLPLHAAHNQL

APBB1

21

O00213
PHPLQFLREANAGNL

ELP6

101

Q0PNE2
PHFGAGLLHISRLLQ

DNHD1

401

Q96M86
VHQLPPGLLSALGQR

DNHD1

1741

Q96M86
GARSLPLSHPLNHLQ

DACH1

406

Q9UI36
SLLRLGTLHQQPLPQ

CCDC157

126

Q569K6
SNLFLAEPHLPEPQL

CDAN1

1196

Q8IWY9
LQGPPQAHQFISLLL

FAM193A

21

P78312
FLISPLPQLLAQEHN

ADAMTS18

176

Q8TE60
GNLLFPHLDFITILP

ADNP2

816

Q6IQ32
LRAGLLEPEVFHLNP

CPT2

166

P23786
PAPGSVILLENLRFH

PGK2

111

P07205
VSNRHLDFLPPGLLL

R3HDM4

246

Q96D70
LGAVLNPHEALAQPL

RAMP2

31

O60895
ELQAFRLHPGPLDLL

TSPOAP1

521

O95153
PLFHSHLENLQRLPP

RFNG

256

Q9Y644
LLLAGEHQQPHFPGL

NUP205

111

Q92621
AAFPALSPAQLHRLL

RADIL

721

Q96JH8
LFRQLHQELPSHGVP

ANAPC5

736

Q9UJX4
PNARALNGFTPLHIA

ANK2

391

Q01484
HLPAALLQPNGLHAS

HEY2

191

Q9UBP5
KLPHFLHPQRNLLQG

MAB21L4

336

Q08AI8
LSDIQQLFLPHGQPF

LPIN3

746

Q9BQK8
LILSLPFCGPHEINH

OR2A14

161

Q96R47
ISQLPFCGPNIIDHL

OR11H6

181

Q8NGC7
ELLDHPFLLQTGLPE

PAK6

651

Q9NQU5
RHPLLLLHQSFQPLE

MDN1

2036

Q9NU22
LQQRLSLFPGTHLTP

HDAC4

381

P56524
NNLNFPPFLPRVLDH

MGAM2

496

Q2M2H8
FRHPNGQIVQLLPLH

MGA

1801

Q8IWI9
QLPALPAQLGALAHL

MFHAS1

146

Q9Y4C4
LSHLPPGFLHLSKLQ

LRRK1

341

Q38SD2
HLAPLNPLLLRQGDF

KIAA1755

91

Q5JYT7
FSIKNLLNGDHHRPP

HMX3

31

A6NHT5
QEKHRGLTAPFLQPL

KIAA2026

91

Q5HYC2
PHLLNQPFSRGSFLI

LINC00312

26

Q9Y6C7
HIADNNPFNLLRIPG

BCL11A

231

Q9H165
AAGAPHLPLELQLRG

BARX1

111

Q9HBU1
NLPQDLHGASPLGVL

C9orf131

606

Q5VYM1
NHGLLPQPEFQQLLR

MGAT5B

511

Q3V5L5
LHPLLHPIFSGQDLQ

GPATCH8

1481

Q9UKJ3
QDLLGAPVLLFLHPE

PER1

386

O15534
GAAHLQHPLSILQPL

PLXND1

446

Q9Y4D7
QLNRFVQLSGRPHLP

KLHDC10

41

Q6PID8
LLHSGFQIPFAVNLP

OR4K17

156

Q8NGC6
DPQSRPLLLLGQLHH

NPEPL1

16

Q8NDH3
GPHAPQLGSLLRALL

PEAK3

346

Q6ZS72
QLSGFPLNILCLLPH

FRYL

2096

O94915
PLNILCLLPHLIQHF

FRYL

2101

O94915
LPSLQSALPFLDLHG

NELFB

41

Q8WX92
LSPSQLLHVLRLAGP

LRRC14B

196

A6NHZ5
HNNLTLLPHDLFTPL

LRRC4C

276

Q9HCJ2
TFPPGLSQLVHLQEL

LRRC8E

451

Q6NSJ5
LPPEVGLLQNLQHLA

LRRC8E

691

Q6NSJ5
PGSHLLLNNPALEFI

POLE

2091

Q07864
LLLGFISHQPTPVIN

NPIPB7

11

O75200
GRQVLPPSELLDHLF

NLRX1

666

Q86UT6
PFHNLGLLIGLFSPR

MROH1

961

Q8NDA8
LLNGGELHRLNIPNP

ITGB4

1566

P16144
LLLGFISHQPTPVIN

NPIPB15

11

A6NHN6
FLSPLNPAHQLGNLR

PIK3CA

751

P42336
DPTALGLAQELPQHL

NLRC5

1676

Q86WI3
EPAFHLLPENLLVSG

NPHP4

196

O75161
IAFHVPAGQPLARNL

HPDL

11

Q96IR7
GLTDHPGLQAPLFLV

OR5AC1

16

P0C628
NGLAPLDITFHLLEP

NPC1L1

211

Q9UHC9
LLDPPGHLTQLGRSF

PROX2

246

Q3B8N5
HHFLIGNNFLPLTIP

ITPRIPL1

491

Q6GPH6
LHLVDAGLAINTPFP

PLA2G4C

381

Q9UP65
LLNRPLSLHLQSPHS

RBBP8NL

291

Q8NC74
RPLLTFLPLNAQENH

C6orf132

76

Q5T0Z8
HGKRLPLTLFPSANL

FHL1

251

Q13642
FHLRLKPNTQLVAPG

ADAMTS3

91

O15072
FLGQLPHGRVLFPLN

CR1

1261

P17927
PHGRVLFPLNLQLGA

CR1

1266

P17927
SHQDNHPLASLPLLG

FARP1

966

Q9Y4F1
QHQPPTLDLLFELLR

ARFGEF3

1471

Q5TH69
QLPNGHVLFPLNLQL

CR1L

356

Q2VPA4
HNGGIPQALPLDRHL

HYAL3

91

O43820
AGQLPLGPHLQDLFT

FAM131A

211

Q6UXB0
SLHLRFLATPPNGNF

DNAJC13

356

O75165
LPNLDLFQGKPHSAL

MAB21L2

321

Q9Y586
PGNLHLVLVLRPTSF

MCF2

21

P10911
SLPLQPFQLAFGHQV

MIDEAS

211

Q6PJG2
LQLGIHGLIPPCFLS

ME3

71

Q16798
HGLIPPCFLSQDVQL

ME3

76

Q16798
LNLCPAGSQHLFPLE

LSMEM1

31

Q8N8F7
LPLPAHLHVFNPREN

KLHDC7B

316

Q96G42
PLISQHLPAGFLSLQ

KRTAP23-1

41

A1A580
SHAIGFPLNVLCLLP

FRY

2136

Q5TBA9
HTLDLRGNQLDTLPP

CHADL

281

Q6NUI6
SFPQLLQNIHCLELP

CENPI

346

Q92674
VTLNLLHGPDLPRIF

PSG11

231

Q9UQ72
LGLLLHPFRDLTQLP

SEC24B

581

O95487
QQPHLPLLSTLAGIR

SCNN1D

476

P51172
PELLQSHFIPTIGRL

RYR1

3351

P21817
LTPLHGILQLRPSFS

POLR3E

126

Q9NVU0
LKRLFNLHLASLPPG

POLR3E

581

Q9NVU0
SNGGIFPETHRPLLL

MEST

176

Q5EB52
LLNPNGPFVLLNHSS

CFAP74

1281

Q9C0B2
PKHQDLQFAGLLNPL

SPOUT1

161

Q5T280
LQFAGLLNPLDSPHH

SPOUT1

166

Q5T280
LPPAQLEGLKNFLHQ

CNTROB

701

Q8N137
RHLVPGAPFLLQALV

C4A

376

P0C0L4
RLALLGLQPAPRFAH

COX8C

16

Q7Z4L0
VNHIGPFLLTHLLLP

DHRS13

141

Q6UX07
VGSFQRLPQLDHPNL

FAM166A

196

Q6J272
DLSHNQLLFFPLLPQ

NRROS

256

Q86YC3
LILRLPFSGPHEINH

OR2A1;

161

Q8NGT9
LLLPLSFCGPQKLNH

OR2A25

161

A4D2G3
FILLGLSHPPNLRSL

OR10G2

16

Q8NGC3
LLPPHLLLNASHGAF

OPRL1

31

P41146
HTSNDFILLGLLPPN

OR2L13

6

Q8N349
LLHQLIFQIPPSRQA

FIBP

76

O43427
LDPQEHLNQGRPHLS

RTEL1

1016

Q9NZ71
LVTTNRLSPHGNFLP

RFPL1

6

O75677
PLHSNLQAHLGQLSP

SOX7

291

Q9BT81
LQLHHLPPEQLATRL

SDHA

366

P31040
HPSLAPLVNILQDAG

TCAF2

96

A6NFQ2
SPGAFIGLHNLLRLH

LRRN3

156

Q9H3W5
QQLPSRGAHVFQPLL

LGI4

446

Q8N135
LPNLDLFQGKPHSAL

MAB21L1

321

Q13394
PQLHFLALQGLNPSR

RNF165

216

Q6ZSG1
LGLPQPDFHSLILDL

SLC26A6

661

Q9BXS9
ALNPAQIFAIHQLGP

NBEA

396

Q8NFP9
PPSLSHILFLLGLLN

GNRHR2

211

Q96P88
HILFLLGLLNAPLDP

GNRHR2

216

Q96P88
NLPLLFLPVHRSHID

GPAM

221

Q9HCL2
HLFNTQHARLAPPSL

PRRC2C

2396

Q9Y520
QLLRENAKAGHPPAL

WDR13

36

Q9H1Z4
SLLHLHPQFAPPNLD

RNF220

91

Q5VTB9
AAPHFLQGLLGLLTP

STRC

211

Q7RTU9
HLPLENFLQLSPHQI

STRC

876

Q7RTU9
FGPHQQDLRIPLTLH

SOX30

251

O94993
LRHPLINPVAFGALL

ABTB1

156

Q969K4
QPTHPIRLGLALNFS

YWHAZ

161

P63104
GLSQPQLHQLLPSEL

BTG2

86

P78543
NLHRPQVHIPSLGFA

AHNAK2

5086

Q8IVF2
HLLIPHGAFQIRNLP

C12orf29

216

Q8N999
TPLGRFLAQLHGEPQ

RNF213

3746

Q63HN8
GRDPPHRQQLFHTLL

TGFBRAP1

706

Q8WUH2
ALPRLLQHAALPGLA

TMEM64

11

Q6YI46
LQHAALPGLAELPAR

TMEM64

16

Q6YI46
GEQHLPQPLLLSRGS

TRIM67

41

Q6ZTA4
QFLSVLPPHLLGRLQ

ZSCAN10

36

Q96SZ4
PIKDQLGLSFHLHLP

ZNF578

151

Q96N58
NIPLHVNADLPSFGR

TRAPPC11

1011

Q7Z392
LAGPTHLFQPSLVLD

RBP3

16

P10745
ILLHPRYFGPNLLNT

POLR2G

11

P62487
PLEPQVLHTLRGLFL

SH2D3A

296

Q9BRG2
FLAPLPHEVTQLRLG

SH3PXD2B

436

A1X283
QPARPGLLLRHNLSG

PFAS

1186

O15067
LPANHPLLTGQRVLD

ATP6V1A

221

P38606
AQLNPHLNLLTPARL

RPS6KL1

251

Q9Y6S9
NILLSLLPLPHHFGT

RALGAPB

616

Q86X10
NPDLITPHGLFILFG

PTBP3

366

O95758
HPALPLLLGATLTFR

TLCD1

6

Q96CP7
LDARPGFGLQHPALQ

ZBTB39

566

O15060
HSQPAALPNLGRLQK

ZNF516-DT

76

Q6ZTR6
QLGLSFLPHPHELQQ

ZNF415

186

Q09FC8
PFLTDILHLTDLPGQ

ZNF416

111

Q9BWM5
PAHVNLGAALLLAPQ

TLCD3B

231

Q71RH2
LQLFNLRPKSHPETG

ZNF217

266

O75362
AAPHFLQGLLGLLTP

STRCP1

211

A6NGW2
HLPLENFLQLSPHQI

STRCP1

876

A6NGW2
LQGLPHIRVFLDNNP

TPBG

281

Q13641
TPQSLPLLLFSHREG

nan

21

Q6ZS46
PGPGRQHLFLLQDEN

TTC39A

166

Q5SRH9
GLRGLLHPQQLHLLS

ZC3H14

556

Q6PJT7
PLITFHLNLPHGNAL

TNRC6A

1806

Q8NDV7
ALLQLHLEQRGPRPS

TUSC1

171

Q2TAM9
GLALLNPALALHPAL

LRRC73

101

Q5JTD7
LAGHLPLGPQLEQLD

LIMK1

611

P53667