Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glutathione binding	GSTM1 GSTM3 GSTM4 GSTM5	4.58e-07	18	72	4	GO:0043295
GeneOntologyMolecularFunction	oligopeptide binding	GSTM1 GSTM3 GSTM4 GSTM5	7.21e-07	20	72	4	GO:1900750
GeneOntologyMolecularFunction	glutathione transferase activity	GSTM1 GSTM3 GSTM4 GSTM5	3.45e-06	29	72	4	GO:0004364
GeneOntologyMolecularFunction	transferase activity, transferring alkyl or aryl (other than methyl) groups	GSTM1 GSTM3 GSTM4 GSTM5	8.38e-05	64	72	4	GO:0016765
GeneOntologyMolecularFunction	amide binding	GSTM1 GSTM3 GSTM4 GSTM5 GLTP GRIA2	7.31e-04	299	72	6	GO:0033218
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF2B MYO18A KIF2A DNAH5	8.75e-04	118	72	4	GO:0003774
GeneOntologyMolecularFunction	modified amino acid binding	GSTM1 GSTM3 GSTM4 GSTM5	9.90e-04	122	72	4	GO:0072341
GeneOntologyBiologicalProcess	nitrobenzene metabolic process	GSTM1 GSTM3 GSTM4	1.49e-07	4	70	3	GO:0018916
GeneOntologyBiologicalProcess	xenobiotic catabolic process	GSTM1 GSTM3 GSTM4 GSTM5	7.38e-06	37	70	4	GO:0042178
GeneOntologyBiologicalProcess	glutathione metabolic process	GSTM1 GSTM3 GSTM4 GSTM5	6.23e-05	63	70	4	GO:0006749
GeneOntologyBiologicalProcess	female gamete generation	PTK2B NDC80 MARF1 MSH5 ZFY SOS1	1.10e-04	223	70	6	GO:0007292
GeneOntologyBiologicalProcess	cellular detoxification of nitrogen compound	GSTM1 GSTM3	1.13e-04	5	70	2	GO:0070458
GeneOntologyBiologicalProcess	detoxification of nitrogen compound	GSTM1 GSTM3	1.13e-04	5	70	2	GO:0051410
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	FSIP2 TUBB6 TUBB3 KIF2B STAG1 NDC80 CC2D1A KIF2A ARMC2 DNAH5	1.51e-04	720	70	10	GO:0000226
GeneOntologyCellularComponent	intercellular bridge	GSTM1 GSTM3 GSTM4 GSTM5 TUBB6 TUBB3 KIF2B	3.44e-08	94	72	7	GO:0045171
Domain	GST_mu	GSTM1 GSTM3 GSTM4 GSTM5	9.56e-10	5	71	4	IPR003081
Domain	GST_N	GSTM1 GSTM3 GSTM4 GSTM5	1.33e-06	22	71	4	PF02798
Domain	GST_NTER	GSTM1 GSTM3 GSTM4 GSTM5	1.33e-06	22	71	4	PS50404
Domain	GST_C	GSTM1 GSTM3 GSTM4 GSTM5	2.69e-06	26	71	4	IPR004046
Domain	GST_C	GSTM1 GSTM3 GSTM4 GSTM5	2.69e-06	26	71	4	PF00043
Domain	Glutathione_S-Trfase_N	GSTM1 GSTM3 GSTM4 GSTM5	3.15e-06	27	71	4	IPR004045
Domain	GST_CTER	GSTM1 GSTM3 GSTM4 GSTM5	8.16e-06	34	71	4	PS50405
Domain	DM14	CC2D1B CC2D1A	1.42e-05	2	71	2	SM00685
Domain	DM14	CC2D1B CC2D1A	1.42e-05	2	71	2	IPR006608
Domain	Glutathione-S-Trfase_C-like	GSTM1 GSTM3 GSTM4 GSTM5	1.43e-05	39	71	4	IPR010987
Domain	-	GSTM1 GSTM3 GSTM4 GSTM5	1.43e-05	39	71	4	1.20.1050.10
Domain	Beta-tubulin_BS	TUBB6 TUBB3	6.29e-04	10	71	2	IPR013838
Domain	GST_C_3	GSTM1 GSTM4	6.29e-04	10	71	2	PF14497
Domain	Beta_tubulin	TUBB6 TUBB3	6.29e-04	10	71	2	IPR002453
Domain	TUBULIN_B_AUTOREG	TUBB6 TUBB3	7.66e-04	11	71	2	PS00228
Domain	-	GSTM1 GSTM3 GSTM4 GSTM5	1.20e-03	122	71	4	3.40.30.10
Domain	Thioredoxin-like_fold	GSTM1 GSTM3 GSTM4 GSTM5	1.61e-03	132	71	4	IPR012336
Domain	-	TUBB6 TUBB3	2.59e-03	20	71	2	3.30.1330.20
Domain	-	TUBB6 TUBB3	2.86e-03	21	71	2	1.10.287.600
Domain	Tubulin_C	TUBB6 TUBB3	3.13e-03	22	71	2	SM00865
Domain	Tubulin_C	TUBB6 TUBB3	3.13e-03	22	71	2	PF03953
Domain	Tubulin/FtsZ_2-layer-sand-dom	TUBB6 TUBB3	3.13e-03	22	71	2	IPR018316
Domain	-	TUBB6 TUBB3	3.13e-03	22	71	2	3.40.50.1440
Domain	Tubulin_C	TUBB6 TUBB3	3.42e-03	23	71	2	IPR023123
Domain	TUBULIN	TUBB6 TUBB3	3.42e-03	23	71	2	PS00227
Domain	Tubulin	TUBB6 TUBB3	3.42e-03	23	71	2	IPR000217
Domain	Tub_FtsZ_C	TUBB6 TUBB3	3.42e-03	23	71	2	IPR008280
Domain	Tubulin	TUBB6 TUBB3	3.42e-03	23	71	2	SM00864
Domain	Tubulin_CS	TUBB6 TUBB3	3.42e-03	23	71	2	IPR017975
Domain	tRNA-bd_arm	SARS1 FYCO1	3.73e-03	24	71	2	IPR010978
Domain	Tubulin_FtsZ_GTPase	TUBB6 TUBB3	3.73e-03	24	71	2	IPR003008
Domain	Tubulin	TUBB6 TUBB3	3.73e-03	24	71	2	PF00091
Domain	VWF_A	COL12A1 COL6A6 GABPB1	6.36e-03	99	71	3	IPR002035
Domain	Spectrin/alpha-actinin	MCF2L2 PLEC	6.57e-03	32	71	2	IPR018159
Domain	SPEC	MCF2L2 PLEC	6.57e-03	32	71	2	SM00150
Pathway	KEGG_MEDICUS_ENV_FACTOR_DCE_TO_DNA_ADDUCTS	GSTM1 GSTM3 GSTM4 GSTM5	8.28e-07	19	56	4	M47809
Pathway	KEGG_MEDICUS_ENV_FACTOR_TCDD_TO_AHR_SIGNALING_PATHWAY	GSTM1 GSTM3 GSTM4 GSTM5	1.87e-06	23	56	4	M47806
Pathway	KEGG_MEDICUS_REFERENCE_KEAP1_NRF2_SIGNALING_PATHWAY	GSTM1 GSTM3 GSTM4 GSTM5	2.24e-06	24	56	4	M47487
Pathway	REACTOME_FLT3_SIGNALING_IN_DISEASE	PTPN11 MYO18A GOLGB1 SOS1	4.26e-06	28	56	4	M41724
Pathway	REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	TUBB6 TUBB3 KIF2B STAG1 NDC80 KIF2A	1.07e-05	127	56	6	M27181
Pathway	REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	TUBB6 TUBB3 KIF2B STAG1 NDC80 KIF2A	1.17e-05	129	56	6	MM14894
Pathway	REACTOME_GLUTATHIONE_CONJUGATION	GSTM1 GSTM3 GSTM4 GSTM5	1.20e-05	36	56	4	M1443
Pathway	REACTOME_MITOTIC_PROMETAPHASE	TUBB6 TUBB3 KIF2B STAG1 NDC80 KIF2A CEP164	1.43e-05	202	56	7	MM15362
Pathway	REACTOME_GLUTATHIONE_CONJUGATION	GSTM1 GSTM3 GSTM4 GSTM5	1.49e-05	38	56	4	MM14600
Pathway	REACTOME_MITOTIC_PROMETAPHASE	TUBB6 TUBB3 KIF2B STAG1 NDC80 KIF2A CEP164	1.52e-05	204	56	7	M4217
Pathway	REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE	TUBB6 TUBB3 KIF2B STAG1 NDC80 CC2D1B KIF2A	3.68e-05	234	56	7	MM14898
Pathway	REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE	TUBB6 TUBB3 KIF2B STAG1 NDC80 CC2D1B KIF2A	3.89e-05	236	56	7	M27185
Pathway	KEGG_GLUTATHIONE_METABOLISM	GSTM1 GSTM3 GSTM4 GSTM5	4.49e-05	50	56	4	M1840
Pathway	REACTOME_SIGNALING_BY_FLT3_FUSION_PROTEINS	MYO18A GOLGB1 SOS1	5.50e-05	19	56	3	M41732
Pathway	KEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION_AT_THE_MINUS_ENDS	TUBB6 TUBB3 KIF2A	6.45e-05	20	56	3	M47911
Pathway	REACTOME_KINESINS	TUBB6 TUBB3 KIF2B KIF2A	7.54e-05	57	56	4	MM15714
Pathway	WP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA	TRPC3 GRIA2 PRKCG	8.67e-05	22	56	3	M39795
Pathway	REACTOME_KINESINS	TUBB6 TUBB3 KIF2B KIF2A	9.85e-05	61	56	4	M977
Pathway	REACTOME_SEPARATION_OF_SISTER_CHROMATIDS	TUBB6 TUBB3 KIF2B STAG1 NDC80 KIF2A	1.06e-04	191	56	6	M29614
Pathway	REACTOME_SEPARATION_OF_SISTER_CHROMATIDS	TUBB6 TUBB3 KIF2B STAG1 NDC80 KIF2A	1.12e-04	193	56	6	MM14890
Pathway	REACTOME_M_PHASE	TUBB6 TUBB3 KIF2B STAG1 NDC80 CC2D1B KIF2A CEP164	1.35e-04	387	56	8	MM15364
Pathway	REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC	TUBB6 TUBB3 CCT4	1.45e-04	26	56	3	M9648
Pathway	REACTOME_SEALING_OF_THE_NUCLEAR_ENVELOPE_NE_BY_ESCRT_III	TUBB6 TUBB3 CC2D1B	1.62e-04	27	56	3	MM15674
Pathway	KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450	GSTM1 GSTM3 GSTM4 GSTM5	1.69e-04	70	56	4	M16794
Pathway	KEGG_DRUG_METABOLISM_CYTOCHROME_P450	GSTM1 GSTM3 GSTM4 GSTM5	1.88e-04	72	56	4	M9257
Pathway	REACTOME_M_PHASE	TUBB6 TUBB3 KIF2B STAG1 NDC80 CC2D1B KIF2A CEP164	2.24e-04	417	56	8	M27662
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	TUBB6 TUBB3 KIF2B NDC80 KIF2A	2.29e-04	140	56	5	M27550
Pathway	WP_PILOCYTIC_ASTROCYTOMA	PTPN11 SOS1	2.30e-04	6	56	2	M39584
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	TUBB6 TUBB3 KIF2B NDC80 KIF2A	2.36e-04	141	56	5	MM15266
Pathway	REACTOME_SEALING_OF_THE_NUCLEAR_ENVELOPE_NE_BY_ESCRT_III	TUBB6 TUBB3 CC2D1B	2.71e-04	32	56	3	M29848
Pathway	BIOCARTA_MET_PATHWAY	PTK2B PTPN11 SOS1	2.98e-04	33	56	3	M19358
Pathway	REACTOME_COOPERATION_OF_PREFOLDIN_AND_TRIC_CCT_IN_ACTIN_AND_TUBULIN_FOLDING	TUBB6 TUBB3 CCT4	2.98e-04	33	56	3	M27297
Pathway	BIOCARTA_MET_PATHWAY	PTK2B PTPN11 SOS1	2.98e-04	33	56	3	MM1494
Pathway	BIOCARTA_HBX_PATHWAY	PTK2B SOS1	3.21e-04	7	56	2	M22037
Pathway	BIOCARTA_HBX_PATHWAY	PTK2B SOS1	3.21e-04	7	56	2	MM1557
Pathway	WP_HEPATOCYTE_GROWTH_FACTOR_RECEPTOR_SIGNALING	PTK2B PTPN11 SOS1	3.26e-04	34	56	3	M39383
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_US27_TO_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY	PTK2B PRKCG	4.27e-04	8	56	2	M47555
Pathway	KEGG_GAP_JUNCTION	TUBB6 TUBB3 PRKCG SOS1	4.43e-04	90	56	4	M4013
Pathway	WP_OXIDATIVE_STRESS_AND_REDOX_PATHWAY	GSTM1 GSTM3 GSTM4 GSTM5	4.81e-04	92	56	4	MM15823
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	TUBB6 TUBB3 PTPN11 COL6A6 PLXNB1 SOS1	5.69e-04	261	56	6	MM15676
Pathway	WP_IL2_SIGNALING	PTK2B PTPN11 SOS1	6.11e-04	42	56	3	M39536
Pathway	REACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC	TUBB6 TUBB3 KIF2B KIF2A	6.11e-04	98	56	4	MM15352
Pathway	KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT	TUBB6 TUBB3 DNAH5	6.55e-04	43	56	3	M47669
Pathway	REACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC	TUBB6 TUBB3 KIF2B KIF2A	6.60e-04	100	56	4	M27650
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PATHWAY_ADAPTOR_PROTEINS	PTPN11 SOS1	6.83e-04	10	56	2	M47930
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT	TUBB6 TUBB3 DNAH5	7.49e-04	45	56	3	M47670
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY	TRPC3 PRKCG	8.33e-04	11	56	2	M49033
Pathway	REACTOME_ACTIVATED_NTRK2_SIGNALS_THROUGH_FRS2_AND_FRS3	PTPN11 SOS1	8.33e-04	11	56	2	M27911
Pathway	REACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS	GSTM1 GSTM3 GSTM4 GSTM5	8.51e-04	107	56	4	MM14595
Pathway	REACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS	GSTM1 GSTM3 GSTM4 GSTM5	9.12e-04	109	56	4	M18788
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	TUBB6 PTK2B TUBB3 KIF2B NDC80 KIF2A RHOT2 PLXNB1 SOS1	9.56e-04	649	56	9	MM15690
Pathway	REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION	TUBB6 TUBB3 KIF2B KIF2A	1.15e-03	116	56	4	MM14855
Pathway	REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	TUBB6 TUBB3 KIF2B KIF2A	1.15e-03	116	56	4	MM15715
Pathway	KEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY	TRPC3 PRKCG	1.18e-03	13	56	2	M47656
Pathway	PID_FGF_PATHWAY	PTK2B PTPN11 SOS1	1.35e-03	55	56	3	M276
Pathway	PID_IL2_1PATHWAY	PTK2B PTPN11 SOS1	1.35e-03	55	56	3	M122
Pathway	REACTOME_SIGNALING_BY_PDGF	PTPN11 COL6A6 SOS1	1.49e-03	57	56	3	MM14713
Pathway	REACTOME_CELL_CYCLE	TUBB6 TUBB3 KIF2B STAG1 NDC80 CC2D1B KIF2A MSH5 CEP164	1.53e-03	694	56	9	M543
Pathway	REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION	TUBB6 TUBB3 KIF2B KIF2A	1.56e-03	126	56	4	M705
Pathway	REACTOME_SIGNALING_BY_PDGF	PTPN11 COL6A6 SOS1	1.57e-03	58	56	3	M2049
Pathway	KEGG_MEDICUS_REFERENCE_CA2_PYK2_RAS_ERK_SIGNALING_PATHWAY	PTK2B SOS1	1.57e-03	15	56	2	M47592
Pathway	REACTOME_CELL_CYCLE_MITOTIC	TUBB6 TUBB3 KIF2B STAG1 NDC80 CC2D1B KIF2A CEP164	1.58e-03	561	56	8	M5336
Pathway	REACTOME_HEMOSTASIS	TUBB6 TUBB3 PTPN11 KIF2B TRPC3 PRKCG KIF2A SOS1	1.76e-03	571	56	8	MM14472
Pathway	REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS	GRIA2 PRKCG	1.79e-03	16	56	2	MM15048
Pathway	REACTOME_SIGNALING_BY_FLT3_ITD_AND_TKD_MUTANTS	PTPN11 SOS1	1.79e-03	16	56	2	M41733
Pathway	REACTOME_SIGNAL_REGULATORY_PROTEIN_FAMILY_INTERACTIONS	PTK2B PTPN11	1.79e-03	16	56	2	M925
Pathway	REACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT	TUBB6 TUBB3 KIF2B KIF2A	1.80e-03	131	56	4	MM15497
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL12A1 COL6A6 PLEC	1.82e-03	61	56	3	M27103
Pathway	REACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT	TUBB6 TUBB3 KIF2B KIF2A	1.96e-03	134	56	4	M27751
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	TUBB6 PTK2B TUBB3 KIF2B NDC80 KIF2A RHOT2 PLXNB1 SOS1	1.97e-03	720	56	9	M41838
Pathway	REACTOME_TIE2_SIGNALING	PTPN11 SOS1	2.03e-03	17	56	2	MM14836
Pathway	SA_PTEN_PATHWAY	PTK2B SOS1	2.03e-03	17	56	2	M12771
Pathway	REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS	GRIA2 PRKCG	2.03e-03	17	56	2	M5488
Pathway	KEGG_MEDICUS_PATHOGEN_ESCHERICHIA_ESPG_TO_MICROTUBULE_RHOA_SIGNALING_PATHWAY	TUBB6 TUBB3	2.03e-03	17	56	2	M47768
Pathway	REACTOME_TRANSPORT_OF_CONNEXONS_TO_THE_PLASMA_MEMBRANE	TUBB6 TUBB3	2.03e-03	17	56	2	MM14731
Pathway	KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY	PTK2B PTPN11 PRKCG SOS1	2.12e-03	137	56	4	M5669
Pathway	WP_ONCOSTATIN_M_SIGNALING	PTK2B PTPN11 SOS1	2.18e-03	65	56	3	M39562
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_DCTN1_TO_RETROGRADE_AXONAL_TRANSPORT	TUBB6 TUBB3	2.28e-03	18	56	2	M47753
Pathway	REACTOME_TIE2_SIGNALING	PTPN11 SOS1	2.28e-03	18	56	2	M11932
Pathway	REACTOME_MECP2_REGULATES_NEURONAL_RECEPTORS_AND_CHANNELS	TRPC3 GRIA2	2.28e-03	18	56	2	M27901
Pathway	WP_NRF2_PATHWAY	GSTM1 GSTM3 GSTM4 GSTM5	2.35e-03	141	56	4	M39454
Pathway	REACTOME_CELL_CYCLE	TUBB6 TUBB3 KIF2B STAG1 NDC80 CC2D1B KIF2A CEP164	2.48e-03	603	56	8	MM14635
Pathway	REACTOME_NUCLEAR_ENVELOPE_NE_REASSEMBLY	TUBB6 TUBB3 CC2D1B	2.48e-03	68	56	3	MM14921
Pathway	KEGG_MEDICUS_ENV_FACTOR_IRON_TO_ANTEROGRADE_AXONAL_TRANSPORT	TUBB6 TUBB3	2.54e-03	19	56	2	M47818
Pathway	KEGG_MEDICUS_ENV_FACTOR_ZN_TO_ANTEROGRADE_AXONAL_TRANSPORT	TUBB6 TUBB3	2.54e-03	19	56	2	M47813
Pathway	REACTOME_FRS_MEDIATED_FGFR3_SIGNALING	PTPN11 SOS1	2.54e-03	19	56	2	MM15245
Pathway	REACTOME_FRS_MEDIATED_FGFR3_SIGNALING	PTPN11 SOS1	2.81e-03	20	56	2	M27519
Pathway	KEGG_MEDICUS_REFERENCE_KINETOCHORE_MICROTUBULE_ATTACHMENT	TUBB6 TUBB3	2.81e-03	20	56	2	M47890
Pathway	BIOCARTA_IGF1_PATHWAY	PTPN11 SOS1	3.10e-03	21	56	2	M2623
Pathway	BIOCARTA_IL6_PATHWAY	PTPN11 SOS1	3.10e-03	21	56	2	M5489
Pathway	REACTOME_TRANSPORT_OF_CONNEXONS_TO_THE_PLASMA_MEMBRANE	TUBB6 TUBB3	3.10e-03	21	56	2	M27067
Pathway	KEGG_MEDICUS_REFERENCE_MICROTUBULE_RHOA_SIGNALING_PATHWAY	TUBB6 TUBB3	3.10e-03	21	56	2	M47767
Pathway	REACTOME_FRS_MEDIATED_FGFR4_SIGNALING	PTPN11 SOS1	3.10e-03	21	56	2	MM15248
Pathway	BIOCARTA_INSULIN_PATHWAY	PTPN11 SOS1	3.10e-03	21	56	2	M765
Pathway	PID_AVB3_INTEGRIN_PATHWAY	PTK2B PTPN11 COL12A1	3.15e-03	74	56	3	M160
Pathway	REACTOME_ER_TO_GOLGI_ANTEROGRADE_TRANSPORT	TUBB6 TUBB3 PPP6R1 GOLGB1	3.39e-03	156	56	4	M27097
Pathway	REACTOME_NUCLEAR_ENVELOPE_NE_REASSEMBLY	TUBB6 TUBB3 CC2D1B	3.40e-03	76	56	3	M27215
Pathway	REACTOME_FRS_MEDIATED_FGFR4_SIGNALING	PTPN11 SOS1	3.40e-03	22	56	2	M27522
Pathway	BIOCARTA_IGF1_PATHWAY	PTPN11 SOS1	3.40e-03	22	56	2	MM1409
Pathway	BIOCARTA_IL6_PATHWAY	PTPN11 SOS1	3.40e-03	22	56	2	MM1415
Pubmed	Glutathione S-transferase variants and hypertension.	GSTM1 GSTM3 GSTM4 GSTM5	8.91e-11	5	73	4	18551009
Pubmed	Genetic variants in GSTM3 gene within GSTM4-GSTM2-GSTM1-GSTM5-GSTM3 cluster influence breast cancer susceptibility depending on GSTM1.	GSTM1 GSTM3 GSTM4 GSTM5	8.91e-11	5	73	4	19856098
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GSTM1 PTK2B TUBB3 PARP1 SARS1 INF2 ETFB XRN1 MYO18A GRIA2 GMFB PRKCG CCT4 KIF2A ALDH1L1 PLEC KANK2 STX1B	6.57e-10	1431	73	18	37142655
Pubmed	The structure of two murine class-mu glutathione transferase genes coordinately induced by butylated hydroxyanisole.	GSTM1 GSTM3 GSTM4	8.87e-09	3	73	3	8512323
Pubmed	A basis for differentiating among the multiple human Mu-glutathione S-transferases and molecular cloning of brain GSTM5.	GSTM1 GSTM3 GSTM5	8.87e-09	3	73	3	8473333
Pubmed	Deduced amino acid sequence, gene structure and chromosomal location of a novel human class Mu glutathione S-transferase, GSTM4.	GSTM1 GSTM4 GSTM5	8.87e-09	3	73	3	8471052
Pubmed	An asparagine-phenylalanine substitution accounts for catalytic differences between hGSTM3-3 and other human class mu glutathione S-transferases.	GSTM3 GSTM4 GSTM5	8.87e-09	3	73	3	10587441
Pubmed	Identification of class-mu glutathione transferase genes GSTM1-GSTM5 on human chromosome 1p13.	GSTM1 GSTM3 GSTM5	3.54e-08	4	73	3	8317488
Pubmed	Molecular cloning and heterologous expression of an alternatively spliced human Mu class glutathione S-transferase transcript.	GSTM1 GSTM3 GSTM4	3.54e-08	4	73	3	8373352
Pubmed	Variation in the GST mu locus and tobacco smoke exposure as determinants of childhood lung function.	GSTM3 GSTM4 GSTM5	3.54e-08	4	73	3	19151192
Pubmed	Purification and characterization of eight glutathione S-transferase isoenzymes of hamster. Comparison of subunit composition of enzymes from liver, kidney, testis, pancreas and trachea.	GSTM1 GSTM3 GSTM4	1.77e-07	6	73	3	1530570
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	FSIP2 PTK2B MYCBP2 XRN1 PRKCG CC2D1A NUB1 KIF2A PLEC EIF3J PITPNC1 GOLGB1	2.26e-07	861	73	12	36931259
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	TUBB6 TUBB3 PARP1 MYO18A FYCO1 DNAH5 GOLGB1	2.88e-07	208	73	7	33230847
Pubmed	ROR2 Downregulation Activates the MSX2/NSUN2/p21 Regulatory Axis and Promotes Dental Pulp Stem Cell Senescence.	GSTM3 PARP1 SARS1 TIGD1 EIF3J GOLGB1	3.52e-07	131	73	6	35356984
Pubmed	LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.	GSTM3 TUBB6 PARP1 INF2 MYO18A CCT4 KIF2A PLEC STK24 GOLGB1	3.73e-07	580	73	10	35676659
Pubmed	Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy.	GSTM1 GSTM3 GSTM4 GSTM5	4.70e-07	30	73	4	20200426
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	TUBB6 TUBB3 XRN1 MARF1 GON4L CC2D1B KIF2A PPP6R1 PLXNB1 SBNO2	1.05e-06	650	73	10	38777146
Pubmed	Tissue-specific expression and subcellular distribution of murine glutathione S-transferase class kappa.	GSTM1 GSTM3 GSTM5	1.45e-06	11	73	3	15100242
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	TUBB6 TUBB3 PARP1 GLTP SARS1 ETFB MYO18A CCT4 PLEC GOLGB1	2.33e-06	711	73	10	33022573
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	INF2 POLG KIF2A RHOT2 MSH5 PLEC PTCH1 STK24 PLXNB1 GOLGB1 SBNO2 STK25	2.52e-06	1084	73	12	11544199
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MYCBP2 INF2 POLG ZNF500 CC2D1A FYCO1 RHOT2 PPP6R1 PLEC PTCH1 SBNO2 CTDSP2	3.07e-06	1105	73	12	35748872
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	GSTM1 MYCBP2 ETFB XRN1 MYO18A GRIA2 PRKCG CCT4 KIF2A PPP6R1 PLEC STX1B	4.19e-06	1139	73	12	36417873
Pubmed	Isolation, characterization, and expression in Escherichia coli of two murine Mu class glutathione S-transferase cDNAs homologous to the rat subunits 3 (Yb1) and 4 (Yb2).	GSTM1 GSTM5	4.35e-06	2	73	2	2689439
Pubmed	Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion.	GSTM1 GSTM4	4.35e-06	2	73	2	3174634
Pubmed	Male-Specific cAMP Signaling in the Hippocampus Controls Spatial Memory Deficits in a Mouse Model of Autism and Intellectual Disability.	CC2D1B CC2D1A	4.35e-06	2	73	2	30732858
Pubmed	Identification of a novel murine glutathione S-transferase class mu gene.	GSTM1 GSTM3	4.35e-06	2	73	2	9480867
Pubmed	Susceptibility genes: GSTM1 and GSTM3 as genetic risk factors in bladder cancer.	GSTM1 GSTM3	4.35e-06	2	73	2	11173863
Pubmed	Gender influences the class III and V β-tubulin ability to predict poor outcome in colorectal cancer.	TUBB6 TUBB3	4.35e-06	2	73	2	22438565
Pubmed	Pi-class glutathione-S-transferase-positive hepatocytes in aging B6C3F1 mice undergo apoptosis induced by dietary restriction.	GSTM1 GSTM5	4.35e-06	2	73	2	8909248
Pubmed	DNA methylation is associated with altered gene expression in AMD.	GSTM1 GSTM5	4.35e-06	2	73	2	22410570
Pubmed	Rationale for reclassification of a distinctive subdivision of mammalian class Mu glutathione S-transferases that are primarily expressed in testis.	GSTM1 GSTM3	4.35e-06	2	73	2	9545290
Pubmed	The association of glutathione S-transferase polymorphisms in patients with osteosarcoma: evidence from a meta-analysis.	GSTM1 GSTM3	4.35e-06	2	73	2	24689813
Pubmed	Increased synthesis of glutathione S-transferases in response to anticarcinogenic antioxidants. Cloning and measurement of messenger RNA.	GSTM1 GSTM3	4.35e-06	2	73	2	6822548
Pubmed	Comparative assessment of gene-specific variant distribution in prenatal and postnatal cohorts tested for Noonan syndrome and related conditions.	PTPN11 SOS1	4.35e-06	2	73	2	29907801
Pubmed	The Freud-1/CC2D1A family: transcriptional regulators implicated in mental retardation.	CC2D1B CC2D1A	4.35e-06	2	73	2	17394259
Pubmed	PARP-1 cooperates with Ptc1 to suppress medulloblastoma and basal cell carcinoma.	PARP1 PTCH1	4.35e-06	2	73	2	18660545
Pubmed	Identification of a unique mu-class glutathione S-transferase in mouse spermatogenic cells.	GSTM1 GSTM3	4.35e-06	2	73	2	8607970
Pubmed	Allelism at the glutathione S-transferase GSTM3 locus: interactions with GSTM1 and GSTT1 as risk factors for astrocytoma.	GSTM1 GSTM3	4.35e-06	2	73	2	8824514
Pubmed	Mst3b, an Ste20-like kinase, regulates axon regeneration in mature CNS and PNS pathways.	STK24 STK25	4.35e-06	2	73	2	19855390
Pubmed	Genomic organization and characterization of the promoter region of murine GSTM2 gene.	GSTM1 GSTM5	4.35e-06	2	73	2	11404019
Pubmed	The Drosophila Notch inhibitor and tumor suppressor gene lethal (2) giant discs encodes a conserved regulator of endosomal trafficking.	CC2D1B CC2D1A	4.35e-06	2	73	2	17084358
Pubmed	Developmental regulation of TRPC3 ion channel expression in the mouse cochlea.	TUBB3 TRPC3	4.35e-06	2	73	2	20229053
Pubmed	GCKIII (Germinal Center Kinase III) Kinases STK24 and STK25 (Serine/Threonine Kinase 24 and 25) Inhibit Cavernoma Development.	STK24 STK25	4.35e-06	2	73	2	35130716
Pubmed	Unravelling of Hidden Secrets: The Tumour Suppressor Lethal (2) Giant Discs (Lgd)/CC2D1, Notch Signalling and Cancer.	CC2D1B CC2D1A	4.35e-06	2	73	2	33034024
Pubmed	SHP2 mediates the protective effect of interleukin-6 against dexamethasone-induced apoptosis in multiple myeloma cells.	PTK2B PTPN11	4.35e-06	2	73	2	10880513
Pubmed	Loss of the Intellectual Disability and Autism Gene Cc2d1a and Its Homolog Cc2d1b Differentially Affect Spatial Memory, Anxiety, and Hyperactivity.	CC2D1B CC2D1A	4.35e-06	2	73	2	29552027
Pubmed	Genotype differences in cognitive functioning in Noonan syndrome.	PTPN11 SOS1	4.35e-06	2	73	2	19077116
Pubmed	Phylogenies of glutathione transferase families.	GSTM1 GSTM3	4.35e-06	2	73	2	16399387
Pubmed	Poly(ADP-ribose) polymerase 1 regulates mitochondrial DNA repair in an NAD-dependent manner.	PARP1 POLG	4.35e-06	2	73	2	33482196
Pubmed	The influence of polymorphisms of glutathione S-transferases M1 and M3 on the development of human urothelial cancer.	GSTM1 GSTM3	4.35e-06	2	73	2	18569590
Pubmed	Progesterone regulation of glutathione S-transferase Mu2 expression in mouse uterine luminal epithelium during preimplantation period.	GSTM1 GSTM5	4.35e-06	2	73	2	18692819
Pubmed	GSTM1 and GSTM5 Genetic Polymorphisms and Expression in Age-Related Macular Degeneration.	GSTM1 GSTM5	4.35e-06	2	73	2	25897651
Pubmed	SOS1 and PTPN11 mutations in five cases of Noonan syndrome with multiple giant cell lesions.	PTPN11 SOS1	4.35e-06	2	73	2	19352411
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	TUBB3 SARS1 MYCBP2 ETFB KIF2A RHOT2 PPP6R1 STK24 STK25	5.03e-06	606	73	9	36538041
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TUBB6 PARP1 MYCBP2 GRIA2 PRKCG CCT4 FYCO1 KIF2A PPP6R1 KANK2 GOLGB1	5.15e-06	963	73	11	28671696
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	GSTM3 GSTM4 TUBB6 TUBB3 PARP1 MYCBP2 CCT4 FYCO1 ALDH1L1 PLEC	7.11e-06	807	73	10	30575818
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	TUBB6 PTPN11 CIB2 MYCBP2 ZNF500 MARF1 GON4L CC2D1B NUB1 EIF3J KANK2 CTDSP2	8.05e-06	1215	73	12	15146197
Pubmed	LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.	TUBB6 TUBB3 SARS1 MYO18A CCT4	1.27e-05	142	73	5	30809309
Pubmed	Association of genetic polymorphism of GSTT1, GSTM1 and GSTM3 in COPD patients in a north Indian population.	GSTM1 GSTM3	1.30e-05	3	73	2	21513434
Pubmed	Altered growth characteristics of skin fibroblasts from wild-derived mice, and genetic loci regulating fibroblast clone size.	GSTM3 GSTM4	1.30e-05	3	73	2	16842493
Pubmed	Purification and characterization of glutathione S-transferase of murine ovary and testis.	GSTM1 GSTM5	1.30e-05	3	73	2	8442656
Pubmed	Freud-2/CC2D1B mediates dual repression of the serotonin-1A receptor gene.	CC2D1B CC2D1A	1.30e-05	3	73	2	21155902
Pubmed	Association of GSTM1, GSTT1, and GSTM3 gene polymorphisms and susceptibility to cervical cancer in a North Indian population.	GSTM1 GSTM3	1.30e-05	3	73	2	18177825
Pubmed	Subunit diversity and tissue distribution of human glutathione S-transferases: interpretations based on electrospray ionization-MS and peptide sequence-specific antisera.	GSTM3 GSTM5	1.30e-05	3	73	2	9230131
Pubmed	Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage.	GSTM1 GSTM5	1.30e-05	3	73	2	32574561
Pubmed	Influence of genetic polymorphisms in GSTM1, GSTM3, GSTT1 and GSTP1 on allograft outcome in renal transplant recipients.	GSTM1 GSTM3	1.30e-05	3	73	2	19486347
Pubmed	Characterization of the human class Mu glutathione S-transferase gene cluster and the GSTM1 deletion.	GSTM1 GSTM5	1.30e-05	3	73	2	9452477
Pubmed	NGS testing for cardiomyopathy: Utility of adding RASopathy-associated genes.	PTPN11 SOS1	1.30e-05	3	73	2	29696744
Pubmed	Metabolic susceptibility genes and prostate cancer risk in a southern European population: the role of glutathione S-transferases GSTM1, GSTM3, and GSTT1 genetic polymorphisms.	GSTM1 GSTM3	1.30e-05	3	73	2	14968442
Pubmed	Antioxidant defense markers modulated by glutathione S-transferase genetic polymorphism: results of lung cancer case-control study.	GSTM1 GSTM3	1.30e-05	3	73	2	18850183
Pubmed	Ciliogenesis and cell cycle alterations contribute to KIF2A-related malformations of cortical development.	TUBB3 KIF2A	1.30e-05	3	73	2	29077851
Pubmed	Polymorphism at GSTM1, GSTM3 and GSTT1 gene loci and susceptibility to oral cancer in an Indian population.	GSTM1 GSTM3	1.30e-05	3	73	2	12016153
Pubmed	Alternative mutations of a positively selected residue elicit gain or loss of functionalities in enzyme evolution.	GSTM1 GSTM4	1.30e-05	3	73	2	16549767
Pubmed	Glutathione S-transferase polymorphisms in osteosarcoma patients.	GSTM1 GSTM3	1.30e-05	3	73	2	20577141
Pubmed	The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.	KIF2B KIF2A	1.30e-05	3	73	2	17538014
Pubmed	Synthetic lethal genetic interactions between Rad54 and PARP-1 in mouse development and oncogenesis.	PARP1 PTCH1	1.30e-05	3	73	2	29254138
Pubmed	Polymorphisms in the glutathione S-transferase mu cluster are associated with tumour progression and patient outcome in colorectal cancer.	GSTM1 GSTM3	1.30e-05	3	73	2	16328000
Pubmed	Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions.	PTK2B SOS1	1.30e-05	3	73	2	7544443
Pubmed	SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein-protein interactions.	STK24 STK25	1.30e-05	3	73	2	23889253
Pubmed	GSTM1, GSTM3 and GSTT1 gene variants and risk of benign prostate hyperplasia in North India.	GSTM1 GSTM3	1.30e-05	3	73	2	19407363
Pubmed	Glutathione-S-transferases and Chemotherapy Resistance of Hodgkin's Lymphoma Cell Lines.	GSTM1 GSTM4	1.30e-05	3	73	2	27466493
Pubmed	Effects of germline mutations in the Ras/MAPK signaling pathway on adaptive behavior: cardiofaciocutaneous syndrome and Noonan syndrome.	PTPN11 SOS1	1.30e-05	3	73	2	20186801
Pubmed	Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.	GSTM1 GSTM3 GSTM4 GSTM5	2.04e-05	76	73	4	19336475
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	TUBB6 TUBB3 PARP1 MYO18A CCT4 PLEC	2.19e-05	268	73	6	33024031
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	GSTM1 TUBB6 TUBB3 PTPN11 FYCO1 PLEC GOLGB1 ZBED5	2.43e-05	564	73	8	21565611
Pubmed	GSTT1, GSTM1, GSTM3 and NAT2 polymorphisms in laryngeal squamous cell carcinoma in a Greek population.	GSTM1 GSTM3	2.60e-05	4	73	2	19922706
Pubmed	Cardiac features of Noonan syndrome in Japanese patients.	PTPN11 SOS1	2.60e-05	4	73	2	35475426
Pubmed	Glutathione S-transferase M1, M3, P1, and T1 genetic polymorphisms and susceptibility to breast cancer.	GSTM1 GSTM3	2.60e-05	4	73	2	11303592
Pubmed	Glutathione S-transferase M3 (A/A) genotype as a risk factor for oral cancer and leukoplakia among Indian tobacco smokers.	GSTM1 GSTM3	2.60e-05	4	73	2	14735473
Pubmed	CC2D1A and CC2D1B regulate degradation and signaling of EGFR and TLR4.	CC2D1B CC2D1A	2.60e-05	4	73	2	27769858
Pubmed	Glutathione-S-transferase M1, M3, T1 and P1 polymorphisms and susceptibility to non-small-cell lung cancer subtypes and hamartomas.	GSTM1 GSTM3	2.60e-05	4	73	2	11740339
Pubmed	Glutathione S-transferase genotypes and stomach cancer in a population-based case-control study in Warsaw, Poland.	GSTM1 GSTM3	2.60e-05	4	73	2	11692073
Pubmed	Polymorphisms in GSTM1, GSTT1, GSTP1, and GSTM3 genes and breast cancer risk in northeastern Mexico.	GSTM1 GSTM3	2.60e-05	4	73	2	26125851
Pubmed	Polymorphic glutathione S-transferase M1 is a risk factor of primary open-angle glaucoma among Estonians.	GSTM1 GSTM3	2.60e-05	4	73	2	11040079
Pubmed	Molecular complex of three testis-specific isozymes associated with the mouse sperm fibrous sheath: hexokinase 1, phosphofructokinase M, and glutathione S-transferase mu class 5.	GSTM1 GSTM3	2.60e-05	4	73	2	19889946
Pubmed	Glutathione S-transferase genetic polymorphisms and individual sensitivity to the ototoxic effect of cisplatin.	GSTM1 GSTM3	2.60e-05	4	73	2	11081456
Pubmed	Prospective study of urinary excretion of 7-methylguanine and the risk of lung cancer: Effect modification by mu class glutathione-S-transferases.	GSTM1 GSTM3	2.60e-05	4	73	2	17565746
Pubmed	Glutathione S-transferases mu 1, theta 1, pi 1, alpha 1 and mu 3 genetic polymorphisms and the risk of colorectal and gastric cancers in humans.	GSTM1 GSTM3	2.60e-05	4	73	2	16886896
Pubmed	Polymorphisms in glutathione S-transferases and non-melanoma skin cancer risk in Australian renal transplant recipients.	GSTM1 GSTM3	2.60e-05	4	73	2	15459020
Pubmed	Axonal pruning is actively regulated by the microtubule-destabilizing protein kinesin superfamily protein 2A.	TUBB3 KIF2A	2.60e-05	4	73	2	23562155
Interaction	BORCS6 interactions	GSTM5 NDC80 RIBC1 FYCO1 PPP6R1 KANK2 CEP164 GOLGB1	1.64e-07	170	72	8	int:BORCS6
Interaction	GSTM5 interactions	GSTM1 GSTM3 GSTM4 GSTM5	1.98e-07	15	72	4	int:GSTM5
Interaction	GSTM2 interactions	GSTM1 GSTM3 GSTM4 GSTM5	1.04e-06	22	72	4	int:GSTM2
Interaction	KCTD13 interactions	PTK2B TUBB3 PARP1 SARS1 INF2 ETFB XRN1 MYO18A GRIA2 GMFB PRKCG CCT4 KIF2A ALDH1L1 PLEC KANK2 STX1B	6.10e-06	1394	72	17	int:KCTD13
Interaction	MAPT interactions	GSTM1 GSTM3 GSTM5 FSIP2 TUBB6 PTK2B TUBB3 PARP1 PTPN11 STAG1 PRKCG CCT4 NUB1 ALDH1L1 STX1B	7.81e-06	1119	72	15	int:MAPT
Interaction	KCNA3 interactions	TUBB6 TUBB3 PARP1 PTPN11 ETFB XRN1 MYO18A CC2D1B CC2D1A CCT4 FYCO1 DNAH5 GOLGB1	1.12e-05	871	72	13	int:KCNA3
Interaction	GSTM3 interactions	GSTM1 GSTM3 GSTM4 GSTM5 PARP1 PTPN11	1.49e-05	148	72	6	int:GSTM3
Interaction	GSTM1 interactions	GSTM1 GSTM3 GSTM5	1.93e-05	15	72	3	int:GSTM1
Interaction	GSTM4 interactions	GSTM3 GSTM4 GSTM5	2.37e-05	16	72	3	int:GSTM4
Interaction	FAM86B2 interactions	TUBB6 TUBB3 CCT4	2.37e-05	16	72	3	int:FAM86B2
Interaction	HDAC1 interactions	TUBB6 TUBB3 PARP1 STAG1 MYCBP2 XRN1 GON4L CCT4 KIF2A PPP6R1 PLEC UHRF2 STK24 GOLGB1	3.18e-05	1108	72	14	int:HDAC1
Interaction	CCDC68 interactions	NDC80 FYCO1 PLEC	6.41e-05	22	72	3	int:CCDC68
Interaction	MSX2 interactions	GSTM3 PARP1 SARS1 TIGD1 EIF3J GOLGB1	6.98e-05	195	72	6	int:MSX2
Interaction	MTDH interactions	TUBB3 NDC80 GRIA2 CCT4 RHOT2 PLEC PTCH1 DNAH5 STK25	7.60e-05	505	72	9	int:MTDH
Interaction	HDAC6 interactions	GSTM3 TUBB6 TUBB3 PARP1 PTPN11 INF2 MYO18A CCT4 KIF2A PLEC STK24 GOLGB1	1.02e-04	929	72	12	int:HDAC6
Cytoband	1p13.3	GSTM1 GSTM3 GSTM4 GSTM5 SARS1	9.18e-08	69	73	5	1p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr1p13	GSTM1 GSTM3 GSTM4 GSTM5 SARS1	2.28e-05	211	73	5	chr1p13
GeneFamily	Glutathione S-transferases	GSTM1 GSTM3 GSTM4 GSTM5	8.58e-07	25	54	4	567
GeneFamily	Protein phosphatase catalytic subunits\|STRIPAK complex	STK24 STK25	1.61e-03	20	54	2	1371
GeneFamily	Tubulins	TUBB6 TUBB3	2.72e-03	26	54	2	778
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	CC2D1B CC2D1A	5.17e-03	36	54	2	823
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	TUBB3 GLTP THSD7A XRN1 MARF1 MYO18A GRIA2 GMFB CCT4 FYCO1 MSH5 PLEC PLXNB1 PCDH17	1.52e-06	1102	72	14	M2369
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	TUBB3 GLTP THSD7A XRN1 MARF1 MYO18A GRIA2 GMFB CCT4 FYCO1 MSH5 PLEC PLXNB1 PCDH17	1.91e-06	1124	72	14	MM1070
Coexpression	GSE17301_CTRL_VS_48H_IFNA2_STIM_CD8_TCELL_DN	PTK2B GLTP PRKCG RHOT2 CEP164 PLXNB1	1.68e-05	196	72	6	M8034
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TUBB6 TUBB3 COL12A1 NDC80 UHRF2	4.67e-06	149	73	5	651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Brinp3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PTK2B INF2 PRKCG ALDH1L1 PITPNC1	7.22e-06	163	73	5	b0aa4a620bd58011225b42ea6dda04e3101ba342
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM1 GSTM5 GRIA2 ALDH1L1 PLXNB1	1.05e-05	176	73	5	ac3dc44755280e36c0947b6de3cd639dc17de8b6
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM1 THSD7A STAG1 COL6A6 XRN1	1.56e-05	191	73	5	7d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	THSD7A MCF2L2 XRN1 TNNI1 UHRF2	1.80e-05	197	73	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GSTM1 GSTM3 GSTM5 ALDH1L1 PLXNB1	1.94e-05	200	73	5	07d942803360e1a1e8e131d6e31c726dd0db1a0b
Computational	ROS metabolism.	GSTM1 GSTM3 GSTM4 GSTM5	4.19e-06	22	55	4	MODULE_310
Drug	N-ethylmaleimide	GSTM1 GSTM3 GSTM4 GSTM5 PARP1 GLTP POLG MYO18A GRIA2 KIF2A STX1B GOLGB1	7.62e-08	511	73	12	CID000004362
Drug	benzyl isothiocyanate	GSTM1 GSTM3 GSTM4 GSTM5 PARP1 CCT4	1.07e-07	71	73	6	CID000002346
Drug	C14791	GSTM1 GSTM3 GSTM4 GSTM5	2.88e-07	18	73	4	CID011954044
Drug	C14793	GSTM1 GSTM3 GSTM4 GSTM5	2.88e-07	18	73	4	CID011954046
Drug	C14803	GSTM1 GSTM3 GSTM4 GSTM5	2.88e-07	18	73	4	CID011954054
Drug	C14805	GSTM1 GSTM3 GSTM4 GSTM5	2.88e-07	18	73	4	CID011954056
Drug	C14804	GSTM1 GSTM3 GSTM4 GSTM5	2.88e-07	18	73	4	CID011954055
Drug	C14806	GSTM1 GSTM3 GSTM4 GSTM5	2.88e-07	18	73	4	CID011954057
Drug	C14848	GSTM1 GSTM3 GSTM4 GSTM5	2.88e-07	18	73	4	CID011954067
Drug	C14856	GSTM1 GSTM3 GSTM4 GSTM5	2.88e-07	18	73	4	CID011954069
Drug	C14855	GSTM1 GSTM3 GSTM4 GSTM5	2.88e-07	18	73	4	CID011954068
Drug	S-(2,2-dichloro-1-hydroxy)ethylglutathione	GSTM1 GSTM3 GSTM4 GSTM5	2.88e-07	18	73	4	CID011954070
Drug	AC1L4MYY	GSTM1 GSTM3 GSTM4 GSTM5	2.88e-07	18	73	4	CID000188517
Drug	Clch2cosg	GSTM1 GSTM3 GSTM4 GSTM5	2.88e-07	18	73	4	CID000163913
Drug	4-hydroxyanisole	GSTM1 GSTM3 GSTM4 GSTM5 NDC80	3.65e-07	46	73	5	CID000009015
Drug	2-(S-glutathionyl) acetyl glutathione	GSTM1 GSTM3 GSTM4 GSTM5	4.53e-07	20	73	4	CID011954072
Drug	C14865	GSTM1 GSTM3 GSTM4 GSTM5	4.53e-07	20	73	4	CID011954073
Drug	1-chloro-2,4-dinitrobenzene-glutathione conjugate	GSTM1 GSTM3 GSTM5	6.28e-07	6	73	3	ctd:C042630
Drug	S-(formylmethyl)glutathione	GSTM1 GSTM3 GSTM4 GSTM5	9.84e-07	24	73	4	CID011954074
Drug	Lithium	GSTM1 GSTM3 GSTM5 PTK2B PARP1 ETFB GRIA2 PRKCG	1.22e-06	246	73	8	ctd:D008094
Drug	hypericin	GSTM1 GSTM3 GSTM4 GSTM5 PARP1 PRKCG	1.30e-06	108	73	6	CID005281051
Drug	diallyl tetrasulfide	GSTM1 GSTM3 GSTM4 GSTM5 TUBB6 TUBB3	1.79e-06	114	73	6	CID000075552
Drug	AC1Q608X	GSTM1 GSTM3 GSTM4 GSTM5	1.88e-06	28	73	4	CID000128466
Drug	AC1L33DC	GSTM1 GSTM3 GSTM4 GSTM5	1.88e-06	28	73	4	CID000133757
Drug	ethoxyquin	GSTM1 GSTM3 GSTM4 GSTM5 PLEC UHRF2	1.98e-06	116	73	6	CID000003293
Drug	2-BHA	GSTM1 GSTM3 GSTM4 GSTM5	2.17e-06	29	73	4	CID000006932
Drug	o-dinitrobenzene	GSTM1 GSTM3 GSTM4 GSTM5	2.87e-06	31	73	4	CID000010707
Drug	Dcvg	GSTM1 GSTM3 GSTM4 GSTM5	2.87e-06	31	73	4	CID006437359
Drug	stilbene oxide	GSTM1 GSTM3 GSTM4 GSTM5 PLEC	4.00e-06	74	73	5	CID000028649
Drug	m-toluidine	GSTM1 GSTM3 GSTM4 GSTM5	4.19e-06	34	73	4	CID000007934
Drug	Lyndiol	GSTM1 GSTM3 GSTM4 GSTM5	4.19e-06	34	73	4	CID000082149
Drug	2,4,6-trinitrotoluene	GSTM1 GSTM3 GSTM4 GSTM5 TNNI1	4.27e-06	75	73	5	CID000008376
Drug	dimethoxystrychnine	GSTM1 GSTM3 GSTM4 GSTM5	4.72e-06	35	73	4	CID000009649
Drug	Dixan	GSTM1 GSTM3 GSTM4 GSTM5	4.72e-06	35	73	4	CID000010404
Drug	Glutathione	GSTM1 GSTM3 GSTM4 GSTM5	5.30e-06	36	73	4	DB00143
Drug	Ethoxyquin	GSTM1 GSTM3 GSTM4 GSTM5	8.14e-06	40	73	4	ctd:D005015
Drug	C14802	GSTM1 GSTM3 GSTM4 GSTM5	1.56e-05	47	73	4	CID011954053
Drug	C14800	GSTM1 GSTM3 GSTM4 GSTM5	1.70e-05	48	73	4	CID011954051
Drug	EUK-189	GSTM1 GSTM4 GSTM5	1.72e-05	16	73	3	ctd:C436526
Drug	bromobenzene-3,4-oxide	GSTM1 GSTM3 GSTM4 GSTM5	1.85e-05	49	73	4	CID000108121
Drug	bromobenzene-2,3-oxide	GSTM1 GSTM3 GSTM4 GSTM5	2.00e-05	50	73	4	CID003036760
Drug	1,1-dichloroethylene epoxide	GSTM1 GSTM3 GSTM4 GSTM5	2.00e-05	50	73	4	CID000119521
Drug	phenanthroline	GSTM1 GSTM3 GSTM4 GSTM5	2.00e-05	50	73	4	CID000067473
Drug	naphthalene epoxide	GSTM1 GSTM3 GSTM4 GSTM5	2.17e-05	51	73	4	CID000108063
Drug	strychnine HCl	GSTM1 GSTM3 GSTM4 GSTM5 GRIA2 PTCH1	2.54e-05	181	73	6	CID000005304
Drug	dichloroacetaldehyde	GSTM1 GSTM3 GSTM4 GSTM5	2.72e-05	54	73	4	CID000006576
Drug	arsenic	GSTM1 GSTM3 GSTM4 GSTM5 PARP1 CCT4 STK25	2.80e-05	274	73	7	CID005359596
Drug	S-hexylglutathione	GSTM1 GSTM3 GSTM4 GSTM5	2.93e-05	55	73	4	CID000005140
Drug	chloroacetyl chloride	GSTM1 GSTM3 GSTM4 GSTM5	2.93e-05	55	73	4	CID000006577
Drug	2-(4-toluidino)-6-naphthalenesulfonic acid	GSTM1 GSTM3	3.04e-05	3	73	2	ctd:C009497
Drug	diepoxybutane	GSTM1 GSTM3 GSTM4 GSTM5 PTCH1	3.16e-05	113	73	5	CID000011254
Drug	cyclohexanone	GSTM1 GSTM3 GSTM4 GSTM5	3.38e-05	57	73	4	CID000007967
Drug	tiadenol	GSTM1 GSTM3 GSTM4 GSTM5	3.38e-05	57	73	4	CID000023403
Drug	perhexiline	GSTM1 GSTM3 GSTM4 GSTM5	3.62e-05	58	73	4	CID000004746
Drug	bromoacetaldehyde	GSTM1 GSTM3 GSTM4 GSTM5	3.62e-05	58	73	4	CID000105131
Drug	Butylated Hydroxyanisole	GSTM1 GSTM3 GSTM4 GSTM5 PARP1	3.89e-05	118	73	5	ctd:D002083
Drug	Pantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; MCF7; HT_HG-U133A	POLG RHOT2 PPP6R1 PLEC PLXNB1 SBNO2	3.97e-05	196	73	6	3248_DN
Drug	4-epidoxorubicin	GSTM1 GSTM3 GSTM4 GSTM5 PARP1 NDC80 POLG MYO18A PRKCG CCT4 SOS1	4.00e-05	788	73	11	CID000001690
Drug	2-butyl-6-methoxyphenol	GSTM1 GSTM3 GSTM4 GSTM5 PARP1 PLEC	4.09e-05	197	73	6	CID011954184
Drug	piriprost	GSTM1 GSTM3 GSTM4 GSTM5	4.14e-05	60	73	4	CID006437373
Drug	Milrinone [78415-72-2]; Down 200; 19uM; PC3; HT_HG-U133A	CIB2 ZNF500 CC2D1A KIF2A PLEC SOS1	4.33e-05	199	73	6	5856_DN
Drug	PenCB	GSTM1 GSTM3 GSTM4 GSTM5	4.42e-05	61	73	4	CID000036188
Drug	NSC39143	GSTM1 GSTM3 GSTM4 GSTM5	4.42e-05	61	73	4	CID000002579
Drug	BP-4,5-oxide	GSTM1 GSTM3 GSTM4 GSTM5	4.42e-05	61	73	4	CID000037786
Drug	Docetaxel trihydrate	TUBB6 TUBB3 PARP1 NDC80 CCT4 PLEC	4.70e-05	202	73	6	CID000003143
Drug	AC1NSK22	GSTM1 GSTM3 GSTM4 GSTM5	6.03e-05	66	73	4	CID005311131
Drug	2-cyclopentyl-5-(5-isoquinolylsulfonyl)-6-nitro-1H-benzo(D)imidazole	PTK2B PARP1	6.06e-05	4	73	2	ctd:C436284
Drug	magnesium	TUBB6 PTK2B TUBB3 SARS1 TRPC3 OXCT2 GRIA2 PRKCG CCT4 PLEC TNNI1 DNAH5 CTDSP2 SOS1	6.95e-05	1325	73	14	CID000000888
Drug	zinc sulfate	GSTM1 GSTM3 GSTM4 GSTM5	7.18e-05	69	73	4	CID000024424
Drug	oltipraz	GSTM1 GSTM3 GSTM4 GSTM5 PLEC	7.93e-05	137	73	5	CID000047318
Drug	1,2-dibromoethane	GSTM1 GSTM3 GSTM4 GSTM5	8.03e-05	71	73	4	CID000007839
Drug	ethacrynic acid	GSTM1 GSTM3 GSTM4 GSTM5 KIF2A	8.21e-05	138	73	5	CID000003278
Drug	CAS 87-33-2	GSTM1 GSTM3 GSTM4 GSTM5	8.95e-05	73	73	4	CID000003780
Drug	clotrimazole	GSTM1 GSTM3 GSTM4 GSTM5 PLEC	9.71e-05	143	73	5	CID000002812
Drug	CoCl2	GSTM1 GSTM3 GSTM4 GSTM5	9.95e-05	75	73	4	CID003015678
Drug	TTEGDA	PTPN11 SOS1	1.01e-04	5	73	2	CID000028803
Drug	AC1NSVYL	CCT4 PTCH1	1.01e-04	5	73	2	CID005317733
Drug	AC1L1CBF	GSTM1 GSTM3 GSTM4 GSTM5 TUBB6 TUBB3 SOS1	1.01e-04	336	73	7	CID000001822
Drug	AC1O5MYK	GSTM1 GSTM3 GSTM4 GSTM5	1.10e-04	77	73	4	CID006437077
Drug	BP-7,8-diol	GSTM1 GSTM3 GSTM4 GSTM5	1.16e-04	78	73	4	CID000025892
Drug	vanadium	GSTM1 GSTM3 GSTM4 GSTM5 GLTP	1.18e-04	149	73	5	CID000023990
Drug	NSC617668	TUBB6 TUBB3 CCT4	1.21e-04	30	73	3	CID000357989
Drug	anti-OX	GSTM1 GSTM3 GSTM4 GSTM5	1.22e-04	79	73	4	CID000008398
Drug	Dietary Fats, Unsaturated	GSTM1 GSTM3 GSTM4 GSTM5	1.22e-04	79	73	4	ctd:D004042
Drug	Methamphetamine	GSTM1 PARP1 NDC80 INF2 XRN1 MYO18A GON4L GRIA2 GMFB CC2D1B PPP6R1 PLEC TNNI1 GOLGB1	1.26e-04	1401	73	14	ctd:D008694
Drug	PCB 126	GSTM1 GSTM3 GSTM4 GSTM5	1.28e-04	80	73	4	CID000063090
Drug	NSC609395	TUBB6 TUBB3 PARP1	1.33e-04	31	73	3	CID005488798
Drug	indole-3-carbinol	GSTM1 GSTM3 GSTM4 GSTM5 PARP1	1.38e-04	154	73	5	CID000003712
Drug	MgCl2	TUBB6 TUBB3 SARS1 POLG OXCT2 MYO18A TNNI1	1.40e-04	354	73	7	CID000024584
Drug	YM928	GRIA2 PTCH1	1.51e-04	6	73	2	CID006918393
Drug	1,2-dichloro-4-nitrobenzene	GSTM1 GSTM3	1.51e-04	6	73	2	ctd:C028328
Drug	phenobarbital	GSTM1 GSTM3 GSTM4 GSTM5 GRIA2 PRKCG PLEC	1.55e-04	360	73	7	CID000004763
Drug	GTP - Na	TUBB6 PTK2B TUBB3 PTPN11 GLTP POLG PRKCG CCT4 RHOT2 EIF3J SOS1	1.63e-04	923	73	11	CID000000762
Drug	phenolate	GSTM1 GSTM3 GSTM4 GSTM5 NDC80 POLG	1.66e-04	254	73	6	CID000000996
Drug	Docosahexaenoic Acids	GSTM1 GSTM3 TUBB3 PARP1 SARS1	1.69e-04	161	73	5	ctd:D004281
Drug	NSC243743	STAG1 POLG OXCT2	1.76e-04	34	73	3	CID000001064
Drug	trichloroethylene	GSTM1 GSTM3 GSTM4 GSTM5	1.85e-04	88	73	4	CID000006575
Drug	1-anilino-4-methyl-2-methylthio-4-phenylimidazolin-5-one	GSTM1 TUBB6 COL12A1 GLTP INF2 ETFB PRKCG	1.93e-04	373	73	7	ctd:C540355
Drug	aminotriazole	GSTM1 GSTM3 GSTM4 GSTM5 ALDH1L1	2.01e-04	167	73	5	CID000001639
Drug	C-1A	PTK2B POLG PRKCG CCT4	2.11e-04	91	73	4	CID009543473
Disease	Brugada syndrome (implicated_via_orthology)	GSTM1 GSTM3 GSTM4 GSTM5	1.14e-10	5	66	4	DOID:0050451 (implicated_via_orthology)
Disease	apolipoprotein A 1 measurement	GSTM1 GSTM5 PTPN11 SARS1 THSD7A STAG1 ETFB EIF3J KANK2 CEP164	1.79e-05	848	66	10	EFO_0004614
Disease	larynx cancer (is_implicated_in)	GSTM1 GSTM3	7.35e-05	6	66	2	DOID:2596 (is_implicated_in)
Disease	Degenerative Diseases, Central Nervous System	GSTM1 GSTM4 GSTM5	9.22e-05	39	66	3	C0270715
Disease	Degenerative Diseases, Spinal Cord	GSTM1 GSTM4 GSTM5	9.22e-05	39	66	3	C0751733
Disease	Neurodegenerative Disorders	GSTM1 GSTM4 GSTM5	9.22e-05	39	66	3	C0524851
Disease	obesity (implicated_via_orthology)	GSTM1 GSTM3 GSTM4 GSTM5 PLXNB1	1.22e-04	215	66	5	DOID:9970 (implicated_via_orthology)
Disease	Noonan syndrome (is_implicated_in)	PTPN11 SOS1	1.37e-04	8	66	2	DOID:3490 (is_implicated_in)
Disease	Noonan syndrome	PTPN11 SOS1	1.76e-04	9	66	2	cv:C0028326
Disease	neuroticism measurement	PTK2B THSD7A STAG1 ETFB TRIM31 MSH5 PTCH1 STK24 STX1B	1.84e-04	909	66	9	EFO_0007660
Disease	Cardiomyopathies	PARP1 PTPN11 POLG SOS1	2.10e-04	130	66	4	C0878544
Disease	facial paralysis (implicated_via_orthology)	TUBB6 TUBB3	2.19e-04	10	66	2	DOID:13934 (implicated_via_orthology)
Disease	complex cortical dysplasia with other brain malformations 7 (implicated_via_orthology)	TUBB6 TUBB3	2.19e-04	10	66	2	DOID:0090132 (implicated_via_orthology)
Disease	ptosis (implicated_via_orthology)	TUBB6 TUBB3	2.19e-04	10	66	2	DOID:0060260 (implicated_via_orthology)
Disease	tubulinopathy (implicated_via_orthology)	TUBB6 TUBB3	2.19e-04	10	66	2	DOID:0112227 (implicated_via_orthology)
Disease	pulmonary function measurement, FEV/FEC ratio	PITPNC1 PTCH1 ARMC2	2.31e-04	53	66	3	EFO_0003892, EFO_0004713
Disease	taste liking measurement	PARP1 THSD7A MYCBP2 TRIM31 KIF2A PCDH17	2.32e-04	388	66	6	EFO_0010155
Disease	Turner Syndrome, Male	PTPN11 SOS1	2.68e-04	11	66	2	C0041409
Disease	Female Pseudo-Turner Syndrome	PTPN11 SOS1	2.68e-04	11	66	2	C1527404
Disease	Noonan Syndrome 1	PTPN11 SOS1	2.68e-04	11	66	2	C4551602
Disease	cerebral cavernous malformation (implicated_via_orthology)	STK24 STK25	2.68e-04	11	66	2	DOID:0060669 (implicated_via_orthology)
Disease	Mental Retardation, Psychosocial	PARP1 STAG1 GON4L PRKCG	2.71e-04	139	66	4	C0025363
Disease	Profound Mental Retardation	PARP1 STAG1 GON4L PRKCG	2.71e-04	139	66	4	C0020796
Disease	Mental deficiency	PARP1 STAG1 GON4L PRKCG	2.71e-04	139	66	4	C0917816
Disease	cerebellar ataxia, mental retardation and dysequlibrium syndrome (implicated_via_orthology)	TUBB6 TUBB3	3.21e-04	12	66	2	DOID:0050997 (implicated_via_orthology)
Disease	N-acetylglycine measurement	ALDH1L1 UHRF2	4.41e-04	14	66	2	EFO_0021002
Disease	RASopathy	PTPN11 SOS1	5.08e-04	15	66	2	cv:C5555857
Disease	Anilide use measurement	MSH5 STK25	5.08e-04	15	66	2	EFO_0009938
Disease	stomach cancer (is_implicated_in)	GSTM1 PTPN11 PTCH1	5.71e-04	72	66	3	DOID:10534 (is_implicated_in)
Disease	multiple sclerosis (is_implicated_in)	GSTM1 GSTM3 POLG	5.94e-04	73	66	3	DOID:2377 (is_implicated_in)
Disease	Parkinson's disease (is_implicated_in)	GSTM1 PARP1 POLG	6.69e-04	76	66	3	DOID:14330 (is_implicated_in)
Disease	apolipoprotein B measurement	GSTM1 GSTM5 PTPN11 SARS1 STAG1 PLEC KANK2	6.92e-04	663	66	7	EFO_0004615
Disease	Asthma	GSTM1 PARP1 DNAH5	7.76e-04	80	66	3	C0004096
Disease	Noonan-Like Syndrome With Loose Anagen Hair	PTPN11 SOS1	8.22e-04	19	66	2	C3501846
Disease	Costello syndrome (disorder)	PTPN11 SOS1	8.22e-04	19	66	2	C0587248
Disease	Noonan syndrome-like disorder with loose anagen hair	PTPN11 SOS1	8.22e-04	19	66	2	C1843181
Disease	Cardio-facio-cutaneous syndrome	PTPN11 SOS1	8.22e-04	19	66	2	C1275081
Disease	Colorectal Carcinoma	GSTM1 GSTM3 PARP1 MCF2L2 ALDH1L1 UHRF2 GABPB1	9.66e-04	702	66	7	C0009402
Disease	LEOPARD Syndrome	PTPN11 SOS1	1.11e-03	22	66	2	C0175704
Disease	Noonan Syndrome	PTPN11 SOS1	1.32e-03	24	66	2	C0028326
Disease	response to venlafaxine	COL12A1 POLG	1.43e-03	25	66	2	EFO_0006328
Disease	status epilepticus (biomarker_via_orthology)	PTK2B POLG GRIA2	1.48e-03	100	66	3	DOID:1824 (biomarker_via_orthology)
Disease	macular degeneration (is_marker_for)	GSTM1 GSTM3	1.55e-03	26	66	2	DOID:4448 (is_marker_for)
Disease	cystic fibrosis (is_implicated_in)	GSTM1 GSTM3	1.67e-03	27	66	2	DOID:1485 (is_implicated_in)
Disease	Autosomal Dominant Parkinsonism	PARP1 POLG	1.79e-03	28	66	2	C0752098
Disease	Autosomal Dominant Juvenile Parkinson Disease	PARP1 POLG	1.79e-03	28	66	2	C0752097
Disease	Parkinsonism, Experimental	PARP1 POLG	1.79e-03	28	66	2	C0752101
Disease	Autosomal Recessive Parkinsonism	PARP1 POLG	1.79e-03	28	66	2	C0752100
Disease	Familial Juvenile Parkinsonism	PARP1 POLG	1.79e-03	28	66	2	C0752104
Disease	Ramsay Hunt Paralysis Syndrome	PARP1 POLG	1.79e-03	28	66	2	C0242423
Disease	PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE	PARP1 POLG	1.79e-03	28	66	2	C1868675
Disease	Malignant mesothelioma	GSTM1 PARP1 COL12A1	1.89e-03	109	66	3	C0345967
Disease	Parkinsonism, Juvenile	PARP1 POLG	2.06e-03	30	66	2	C0752105
Disease	Parkinsonian Disorders	PARP1 POLG	2.06e-03	30	66	2	C0242422
Disease	intellectual disability (is_implicated_in)	SARS1 CC2D1A	2.06e-03	30	66	2	DOID:1059 (is_implicated_in)
Disease	serum albumin measurement	PTPN11 ETFB PLEC EIF3J ARMC2 SOS1	2.09e-03	592	66	6	EFO_0004535

Protein segments in the cluster

Peptide	Gene	Start	Entry
EVLAREDIDEAVCAI	FAM228A	31	Q86W67
VEIEVLVDADCVVDS	ACOT7L	226	Q6ZUV0
ILRELEKEENIETVC	ARMC2	276	Q8NEN0
EEVVREIDKLLQDCR	PCDH17	1136	O14917
LEVIDIFKIEREGEC	PARP1	831	P09874
VEKVIEEIRCKAIER	NUB1	56	Q9Y5A7
LCGETEEEKIRVDIL	GSTM5	86	P46439
EVLVRDVCISLEIDD	EIF3J	181	O75822
QVCALTVEKERVEEA	FYCO1	911	Q9BQS8
TVEKERVEEALACAV	FYCO1	916	Q9BQS8
CIEIIENRVESAEIE	GABPB1	331	Q06547
AEVFVEQCEREKEIL	FSIP2	731	Q5CZC0
VIEDLIKSCELAVDL	MCF2L2	811	Q86YR7
RVILDCERDKVNDIV	GRIA2	206	P42262
LEGLEVVVEARVECE	PLXNB1	956	O43157
IVVDERRAVEELLEC	MYO18A	1141	Q92614
EERALVFDVEVCLAE	POLG	191	P54098
CGETEEEKIRVDIIE	GSTM3	91	P21266
DDVDCTLVEKRVLAL	PRKCG	391	P05129
IDIIREKGVDCDIDV	PTPN11	476	Q06124
ECTLEEVVERLLSVK	INF2	331	Q27J81
VVGLQEREVKCVEDV	KIF2A	396	O00139
EREVKCVEDVLKLID	KIF2A	401	O00139
VCLDAEVRVVLVALD	FER1L6-AS2	16	Q96M78
ECLTRAEADIVLLVD	COL12A1	1191	Q99715
EEDQGRICVVIDLDE	CTDSP2	96	O14595
ERDICDDIKVEHAVE	GON4L	1341	Q3T8J9
LKLDALEIACEVREI	CC2D1A	756	Q6P1N0
LEIACEVREILEVLD	CC2D1A	761	Q6P1N0
KLERLENECEIREIV	CC2D1B	801	Q5T0F9
ENECEIREIVEVLDG	CC2D1B	806	Q5T0F9
VTEEECLEKIRLFLV	GLTP	171	Q9NZD2
ECGEEKILTLTEVER	MARF1	1321	Q9Y4F3
RVDVVKALLACEADV	KANK2	751	Q63ZY3
VDVEKEDVRILKVCF	PTK2B	31	Q14289
ECKRIEVLDVVFVID	COL6A6	801	A6NMZ7
IEDICISAVKERDIE	DNAH5	1531	Q8TE73
EKEVCCVEEVLNLVE	KIF2B	391	Q8N4N8
VEEEEELAEIHLCVL	MSH5	41	O43196
VVCDVAEDLVEKLRK	GMFB	6	P60983
DLDELILECVEIERK	RTL5	296	Q5HYW3
VRLLIDEAILKCDAE	SARS1	106	P49591
LLEDIKVVLCRSEEF	TRIM31	246	Q9BZY9
KVVDEEFCADIELII	THSD7A	1381	Q9UPZ6
EELREEIHKANVVCV	RHOT2	66	Q8IXI1
VVAIKIIDLEEAEDE	STK24	61	Q9Y6E0
LCGETEEEKIRVDIL	GSTM4	86	Q03013
FCEIAVEEAVRLKEK	ETFB	41	P38117
LCGETEEEKIRVDIL	GSTM1	86	P09488
KVEVIELQDVECEER	PTCH1	1426	Q13635
KDIEREDIEFICKTI	CCT4	326	P50991
LVELAREELARDKCV	SBNO2	556	Q9Y2G9
VSREEVDVAKVELLC	SLC41A3	171	Q96GZ6
EVGLCEVFELIKETR	MYCBP2	201	O75592
EKCIVETENLEERVA	SOS1	836	Q07889
RCVDRIITEKAVFDV	OXCT2	461	Q9BYC2
VAIKIIDLEEAEDEI	STK25	46	O00506
DVVRLVEEVKELCDG	ALDH1L1	356	O75891
LREKLCQEEEEEILR	CEP164	621	Q9UPV0
DEEEVVLVCDKVIEE	CIB2	141	O75838
DCKIISVDEIFKIER	UHRF2	296	Q96PU4
VLELEEQERELCAVF	RIBC1	321	Q8N443
ELVDAVLDVVRKECE	TUBB6	111	Q9BUF5
ADVVEIAKELELEVE	TIGD1	426	Q96MW7
VEEIRGCIEKLSEDV	STX1B	36	P61266
VEREVCFIDIACDEI	PITPNC1	131	Q9UKF7
ILDAAIVEKIEEEVE	XRN1	1051	Q8IZH2
CRELHAKVEVVDEER	TNNI1	66	P19237
RDAIAEIRAICIEEI	STAG1	301	Q8WVM7
ELVDSVLDVVRKECE	TUBB3	111	Q13509
LLEEIERHGEKVEEC	PLEC	1391	Q15149
ELLDEEDVLQECKVV	PPP6R1	26	Q9UPN7
RIKDLAADIEEELVC	ZBED5	251	Q49AG3
AADIEEELVCRLKIC	ZBED5	256	Q49AG3
EILIVKVEEDFCLEE	ZNF500	21	O60304
VLDLCRDSEEVEAIL	TRPC3	261	Q13507
DVVIEEDVQCSDILE	ZFY	71	P08048
SQKRIAELEEELVCV	GOLGB1	2651	Q14789
AELEEELVCVQKEAA	GOLGB1	2656	Q14789
LNEEIARVELECETI	NDC80	331	O14777