Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL4A1 THSD4 COL4A4 FBLN2 COL16A1 IMPG1 OTOL1 TNXB	2.97e-06	188	94	8	GO:0005201
GeneOntologyMolecularFunction	extracellular matrix structural constituent conferring tensile strength	COL4A1 COL4A4 COL16A1 OTOL1	6.46e-05	46	94	4	GO:0030020
GeneOntologyMolecularFunction	hydrolase activity, acting on carbon-sulfur bonds	AHCYL1 AHCYL2	6.56e-05	3	94	2	GO:0046508
GeneOntologyMolecularFunction	adenosylhomocysteinase activity	AHCYL1 AHCYL2	6.56e-05	3	94	2	GO:0004013
GeneOntologyMolecularFunction	transition metal ion binding	TXNRD1 TRIM33 ZMYND11 ADAMTS3 ADAMTS2 PRICKLE3 C11orf54 AIRE CUL9 MIB2 GRIN2B HERC2 FLG2 ZKSCAN5 PPM1N ZMYM4	1.27e-04	1189	94	16	GO:0046914
GeneOntologyMolecularFunction	group III metabotropic glutamate receptor activity	GRM4 GRM6	1.31e-04	4	94	2	GO:0001642
GeneOntologyMolecularFunction	zinc ion binding	TRIM33 ZMYND11 ADAMTS3 ADAMTS2 PRICKLE3 C11orf54 AIRE CUL9 MIB2 GRIN2B HERC2 ZKSCAN5 ZMYM4	2.70e-04	891	94	13	GO:0008270
GeneOntologyMolecularFunction	glutamate receptor activity	GRIN2B GRM4 GRM6	2.72e-04	27	94	3	GO:0008066
GeneOntologyMolecularFunction	3-chloroallyl aldehyde dehydrogenase activity	ALDH1A2 ALDH1A3	4.53e-04	7	94	2	GO:0004028
GeneOntologyMolecularFunction	poly-ADP-D-ribose binding	HPF1 APLF	6.03e-04	8	94	2	GO:0072572
GeneOntologyMolecularFunction	G protein-coupled glutamate receptor activity	GRM4 GRM6	7.73e-04	9	94	2	GO:0098988
GeneOntologyMolecularFunction	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	GRM4 GRM6	7.73e-04	9	94	2	GO:0001640
GeneOntologyBiologicalProcess	extracellular matrix organization	COL4A1 THSD4 COL4A4 ZNF469 COL16A1 IMPG1 ADAMTS3 ADAMTS2 OTOL1 LCP1 TNXB	8.42e-07	377	91	11	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	COL4A1 THSD4 COL4A4 ZNF469 COL16A1 IMPG1 ADAMTS3 ADAMTS2 OTOL1 LCP1 TNXB	8.64e-07	378	91	11	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	COL4A1 THSD4 COL4A4 ZNF469 COL16A1 IMPG1 ADAMTS3 ADAMTS2 OTOL1 LCP1 TNXB	8.87e-07	379	91	11	GO:0045229
GeneOntologyBiologicalProcess	tissue morphogenesis	TXNRD1 COL4A1 SOX11 ALDH1A2 AIRE WDR1 ALDH1A3 ARHGAP35 FLG2 LCP1 IRX2 MYLK2 EXOC4	2.46e-05	750	91	13	GO:0048729
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL4A1 THSD4 COL4A4 FBLN2 COL16A1 IMPG1 ADAMTS3 ADAMTS2 CFP OTOL1 TNXB	1.71e-05	530	90	11	GO:0062023
GeneOntologyCellularComponent	extracellular matrix	COL4A1 THSD4 COL4A4 FBLN2 COL16A1 IMPG1 ADAMTS3 ADAMTS2 CFP OTOL1 TNXB	1.17e-04	656	90	11	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL4A1 THSD4 COL4A4 FBLN2 COL16A1 IMPG1 ADAMTS3 ADAMTS2 CFP OTOL1 TNXB	1.20e-04	658	90	11	GO:0030312
GeneOntologyCellularComponent	collagen type IV trimer	COL4A1 COL4A4	2.72e-04	6	90	2	GO:0005587
GeneOntologyCellularComponent	basement membrane collagen trimer	COL4A1 COL4A4	5.05e-04	8	90	2	GO:0098651
GeneOntologyCellularComponent	network-forming collagen trimer	COL4A1 COL4A4	5.05e-04	8	90	2	GO:0098642
GeneOntologyCellularComponent	collagen network	COL4A1 COL4A4	5.05e-04	8	90	2	GO:0098645
GeneOntologyCellularComponent	collagen trimer	COL4A1 COL4A4 COL16A1 OTOL1	5.69e-04	88	90	4	GO:0005581
Domain	TSP_1	THSD4 ADAMTS3 ADAMTS2 CFP THSD7B	1.46e-05	63	92	5	PF00090
Domain	TSP1	THSD4 ADAMTS3 ADAMTS2 CFP THSD7B	1.70e-05	65	92	5	SM00209
Domain	TSP1_rpt	THSD4 ADAMTS3 ADAMTS2 CFP THSD7B	1.70e-05	65	92	5	IPR000884
Domain	TSP1	THSD4 ADAMTS3 ADAMTS2 CFP THSD7B	1.70e-05	65	92	5	PS50092
Domain	RhoGAP-FF1	ARHGAP5 ARHGAP35	2.40e-05	2	92	2	PF16512
Domain	RhoGAP-FF1	ARHGAP5 ARHGAP35	2.40e-05	2	92	2	IPR032835
Domain	Cul7	CUL9 HERC2	7.18e-05	3	92	2	PF11515
Domain	S-Ado-L-homoCys_hydrolase_CS	AHCYL1 AHCYL2	7.18e-05	3	92	2	IPR020082
Domain	AdoHcyase_NAD	AHCYL1 AHCYL2	7.18e-05	3	92	2	SM00997
Domain	AdoHcyase	AHCYL1 AHCYL2	7.18e-05	3	92	2	SM00996
Domain	AdoHcyase_NAD	AHCYL1 AHCYL2	7.18e-05	3	92	2	PF00670
Domain	ADOHCYASE_1	AHCYL1 AHCYL2	7.18e-05	3	92	2	PS00738
Domain	ADOHCYASE_2	AHCYL1 AHCYL2	7.18e-05	3	92	2	PS00739
Domain	AdoHcyase	AHCYL1 AHCYL2	7.18e-05	3	92	2	PF05221
Domain	Adenosylhomocysteinase	AHCYL1 AHCYL2	7.18e-05	3	92	2	IPR000043
Domain	CPH_domain	CUL9 HERC2	7.18e-05	3	92	2	IPR021097
Domain	Ado_hCys_hydrolase_NAD-bd	AHCYL1 AHCYL2	7.18e-05	3	92	2	IPR015878
Domain	PLAC	THSD4 ADAMTS3 ADAMTS2	1.06e-04	19	92	3	PS50900
Domain	PLAC	THSD4 ADAMTS3 ADAMTS2	1.06e-04	19	92	3	IPR010909
Domain	RHO	RHOD RHOV RHOF	1.24e-04	20	92	3	PS51420
Domain	Mib_Herc2	MIB2 HERC2	1.43e-04	4	92	2	IPR010606
Domain	MIB_HERC2	MIB2 HERC2	1.43e-04	4	92	2	PS51416
Domain	MIB_HERC2	MIB2 HERC2	1.43e-04	4	92	2	PF06701
Domain	ADAM_spacer1	THSD4 ADAMTS3 ADAMTS2	1.91e-04	23	92	3	IPR010294
Domain	ADAM_spacer1	THSD4 ADAMTS3 ADAMTS2	1.91e-04	23	92	3	PF05986
Domain	FF	ARHGAP5 ARHGAP35	3.55e-04	6	92	2	PF01846
Domain	C4	COL4A1 COL4A4	3.55e-04	6	92	2	SM00111
Domain	FF	ARHGAP5 ARHGAP35	3.55e-04	6	92	2	SM00441
Domain	-	COL4A1 COL4A4	3.55e-04	6	92	2	2.170.240.10
Domain	Collagen_VI_NC	COL4A1 COL4A4	3.55e-04	6	92	2	IPR001442
Domain	FF_domain	ARHGAP5 ARHGAP35	3.55e-04	6	92	2	IPR002713
Domain	C4	COL4A1 COL4A4	3.55e-04	6	92	2	PF01413
Domain	FF	ARHGAP5 ARHGAP35	3.55e-04	6	92	2	PS51676
Domain	NC1_IV	COL4A1 COL4A4	3.55e-04	6	92	2	PS51403
Domain	APC_su10/DOC_dom	CUL9 HERC2	4.96e-04	7	92	2	IPR004939
Domain	DOC	CUL9 HERC2	4.96e-04	7	92	2	PS51284
Domain	APC10	CUL9 HERC2	4.96e-04	7	92	2	SM01337
Domain	ANAPC10	CUL9 HERC2	4.96e-04	7	92	2	PF03256
Domain	Ras	ARHGAP5 RHOD RHOV ARHGAP35 RHOF	5.63e-04	136	92	5	PF00071
Domain	GPCR_3_mtglu_rcpt	GRM4 GRM6	6.59e-04	8	92	2	IPR000162
Domain	ANF_lig-bd_rcpt	GRIN2B GRM4 GRM6	7.96e-04	37	92	3	IPR001828
Domain	ANF_receptor	GRIN2B GRM4 GRM6	7.96e-04	37	92	3	PF01094
Domain	Collagen	COL4A1 COL4A4 COL16A1 OTOL1	8.23e-04	85	92	4	IPR008160
Domain	Collagen	COL4A1 COL4A4 COL16A1 OTOL1	8.23e-04	85	92	4	PF01391
Domain	Peptidase_M12B_N	ADAMTS3 ADAMTS2 ADAM23	9.30e-04	39	92	3	IPR002870
Domain	Pep_M12B_propep	ADAMTS3 ADAMTS2 ADAM23	9.30e-04	39	92	3	PF01562
Domain	Peripla_BP_I	GRIN2B GRM4 GRM6	9.30e-04	39	92	3	IPR028082
Domain	DISINTEGRIN_1	ADAMTS3 ADAMTS2 ADAM23	1.00e-03	40	92	3	PS00427
Domain	Reprolysin	ADAMTS3 ADAMTS2 ADAM23	1.00e-03	40	92	3	PF01421
Domain	ADAM_MEPRO	ADAMTS3 ADAMTS2 ADAM23	1.00e-03	40	92	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS3 ADAMTS2 ADAM23	1.00e-03	40	92	3	PS50214
Domain	Peptidase_M12B	ADAMTS3 ADAMTS2 ADAM23	1.00e-03	40	92	3	IPR001590
Domain	Disintegrin_dom	ADAMTS3 ADAMTS2 ADAM23	1.08e-03	41	92	3	IPR001762
Domain	Small_GTPase	ARHGAP5 RHOD RHOV ARHGAP35 RHOF	1.17e-03	160	92	5	IPR001806
Domain	NCD3G	GRM4 GRM6	1.81e-03	13	92	2	PF07562
Domain	GPCR_3_9-Cys_dom	GRM4 GRM6	1.81e-03	13	92	2	IPR011500
Domain	P_typ_ATPase_c	ATP9B ATP9A	2.10e-03	14	92	2	IPR032630
Domain	P-type_ATPase_N	ATP9B ATP9A	2.10e-03	14	92	2	IPR032631
Domain	P-type_ATPase_IV	ATP9B ATP9A	2.10e-03	14	92	2	IPR006539
Domain	GPCR_3_CS	GRM4 GRM6	2.10e-03	14	92	2	IPR017979
Domain	PhoLip_ATPase_C	ATP9B ATP9A	2.10e-03	14	92	2	PF16212
Domain	PhoLip_ATPase_N	ATP9B ATP9A	2.10e-03	14	92	2	PF16209
Domain	N2O_reductase_N	AAAS WDR1	2.42e-03	15	92	2	IPR011045
Domain	Ald_DH_CS_GLU	ALDH1A2 ALDH1A3	2.75e-03	16	92	2	IPR029510
Domain	Ald_DH_CS_CYS	ALDH1A2 ALDH1A3	3.11e-03	17	92	2	IPR016160
Domain	Rib_L2_dom2	CUL9 HERC2	3.49e-03	18	92	2	IPR014722
Domain	ALDEHYDE_DEHYDR_GLU	ALDH1A2 ALDH1A3	3.49e-03	18	92	2	PS00687
Domain	ZZ	MIB2 HERC2	3.49e-03	18	92	2	PF00569
Domain	-	CUL9 HERC2	3.49e-03	18	92	2	2.30.30.30
Domain	ZF_ZZ_2	MIB2 HERC2	3.49e-03	18	92	2	PS50135
Domain	ZF_ZZ_1	MIB2 HERC2	3.49e-03	18	92	2	PS01357
Domain	ALDEHYDE_DEHYDR_CYS	ALDH1A2 ALDH1A3	3.49e-03	18	92	2	PS00070
Domain	Znf_ZZ	MIB2 HERC2	3.89e-03	19	92	2	IPR000433
Domain	Ald_DH_C	ALDH1A2 ALDH1A3	3.89e-03	19	92	2	IPR016163
Domain	Ald_DH_N	ALDH1A2 ALDH1A3	3.89e-03	19	92	2	IPR016162
Domain	Ald_DH/histidinol_DH	ALDH1A2 ALDH1A3	3.89e-03	19	92	2	IPR016161
Domain	-	ALDH1A2 ALDH1A3	3.89e-03	19	92	2	3.40.605.10
Domain	Aldedh	ALDH1A2 ALDH1A3	3.89e-03	19	92	2	PF00171
Domain	Aldehyde_DH_dom	ALDH1A2 ALDH1A3	3.89e-03	19	92	2	IPR015590
Domain	-	ALDH1A2 ALDH1A3	3.89e-03	19	92	2	3.40.309.10
Domain	ZnF_ZZ	MIB2 HERC2	3.89e-03	19	92	2	SM00291
Domain	Zinc_finger_PHD-type_CS	TRIM33 ZMYND11 AIRE	4.05e-03	65	92	3	IPR019786
Domain	RCC1	FBXO24 HERC2	4.30e-03	20	92	2	PF00415
Domain	GPCR_3	GRM4 GRM6	4.74e-03	21	92	2	IPR000337
Domain	RCC1_1	FBXO24 HERC2	4.74e-03	21	92	2	PS00625
Domain	RCC1_2	FBXO24 HERC2	4.74e-03	21	92	2	PS00626
Domain	RCC1_3	FBXO24 HERC2	4.74e-03	21	92	2	PS50012
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD4 ADAMTS3 ADAMTS2 CFP THSD7B	1.23e-06	39	69	5	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD4 ADAMTS3 ADAMTS2 CFP THSD7B	1.23e-06	39	69	5	MM15165
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL4A1 COL4A4 COL16A1 ADAMTS3 ADAMTS2	1.17e-05	61	69	5	MM14637
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL4A1 COL4A4 COL16A1 ADAMTS3 ADAMTS2	1.85e-05	67	69	5	M26999
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	THSD4 ADAMTS3 ADAMTS2 CFP THSD7B	1.99e-05	68	69	5	M27303
Pathway	REACTOME_COLLAGEN_FORMATION	COL4A1 COL4A4 COL16A1 ADAMTS3 ADAMTS2	3.42e-05	76	69	5	MM14573
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	THSD4 ADAMTS3 ADAMTS2 CFP THSD7B GFPT1	6.95e-05	143	69	6	M27275
Pathway	REACTOME_COLLAGEN_FORMATION	COL4A1 COL4A4 COL16A1 ADAMTS3 ADAMTS2	7.72e-05	90	69	5	M631
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD4 ADAMTS3 ADAMTS2 CFP THSD7B	1.91e-04	109	69	5	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD4 ADAMTS3 ADAMTS2 CFP THSD7B	2.08e-04	111	69	5	M27416
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL4A1 COL4A4 FBLN2 COL16A1 ADAMTS3 ADAMTS2 TNXB	2.60e-04	258	69	7	MM14572
Pathway	WP_FOCAL_ADHESION	COL4A1 COL4A4 ARHGAP5 ARHGAP35 TNXB MYLK2	4.20e-04	199	69	6	M39402
Pathway	KEGG_FOCAL_ADHESION	COL4A1 COL4A4 ARHGAP5 ARHGAP35 TNXB MYLK2	4.20e-04	199	69	6	M7253
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL4A1 COL4A4 FBLN2 COL16A1 ADAMTS3 ADAMTS2 TNXB	6.43e-04	300	69	7	M610
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	JAK1 TRIM33 ARHGAP5 AHCYL1 WAPL ADAM23 HPF1 AIRE CUL9 GRIN2B HERC2 DNAJA1 ZKSCAN5 GFPT1 ZMYM4 EXOC4	3.89e-07	1285	95	16	35914814
Pubmed	Mice develop normally without tenascin.	COL4A1 COL4A4 TNXB	1.09e-06	8	95	3	1383086
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	THSD4 ADAMTS3 ADAMTS2 CFP THSD7B	2.03e-06	75	95	5	20637190
Pubmed	Binding of mouse and human fibulin-2 to extracellular matrix ligands.	COL4A1 COL4A4 FBLN2	3.21e-06	11	95	3	7500359
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	COL4A1 THSD4 COL4A4 FBLN2 COL16A1 TNXB	4.13e-06	153	95	6	25037231
Pubmed	IRBIT plays an important role in NHE3-mediated pHi regulation in HSG cells.	AHCYL1 SLC9A3	7.38e-06	2	95	2	23769829
Pubmed	RhoA is down-regulated at cell-cell contacts via p190RhoGAP-B in response to tensional homeostasis.	ARHGAP5 ARHGAP35	7.38e-06	2	95	2	23552690
Pubmed	Hair cycle-specific immunolocalization of retinoic acid synthesizing enzymes Aldh1a2 and Aldh1a3 indicate complex regulation.	ALDH1A2 ALDH1A3	7.38e-06	2	95	2	15245423
Pubmed	Retinoids control anterior and dorsal properties in the developing forebrain.	ALDH1A2 ALDH1A3	7.38e-06	2	95	2	17184764
Pubmed	Raldh3 expression in diabetic islets reciprocally regulates secretion of insulin and glucagon from pancreatic islets.	ALDH1A2 ALDH1A3	7.38e-06	2	95	2	20833146
Pubmed	The p190 RhoGAPs, ARHGAP35, and ARHGAP5 are implicated in GnRH neuronal development: Evidence from patients with idiopathic hypogonadotropic hypogonadism, zebrafish, and in vitro GAP activity assay.	ARHGAP5 ARHGAP35	7.38e-06	2	95	2	36178483
Pubmed	Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner.	MIB2 GRIN2B	7.38e-06	2	95	2	17962190
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	PTGR1 C11orf54 SHMT1 FLG2 LCP1 GFPT1 EXOC4	2.08e-05	304	95	7	32235678
Pubmed	The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology.	ADAMTS3 ADAMTS2	2.21e-05	3	95	2	25863161
Pubmed	RALDH3, a retinaldehyde dehydrogenase that generates retinoic acid, is expressed in the ventral retina, otic vesicle and olfactory pit during mouse development.	ALDH1A2 ALDH1A3	2.21e-05	3	95	2	11025231
Pubmed	Induction of complementary function reductase enzymes in colon cancer cells by dithiole-3-thione versus sodium selenite.	TXNRD1 PTGR1	2.21e-05	3	95	2	25179160
Pubmed	Consequences of lineage-specific gene loss on functional evolution of surviving paralogs: ALDH1A and retinoic acid signaling in vertebrate genomes.	ALDH1A2 ALDH1A3	2.21e-05	3	95	2	19478994
Pubmed	BS69, a specific adaptor in the latent membrane protein 1-mediated c-Jun N-terminal kinase pathway.	ZMYND11 PDLIM7	2.21e-05	3	95	2	16382137
Pubmed	Retinaldehyde dehydrogenase 2 (RALDH2)- independent patterns of retinoic acid synthesis in the mouse embryo.	ALDH1A2 ALDH1A3	2.21e-05	3	95	2	12454286
Pubmed	Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3.	ADAMTS3 ADAMTS2	2.21e-05	3	95	2	11741898
Pubmed	Cisplatin-resistant cells in malignant pleural mesothelioma cell lines show ALDH(high)CD44(+) phenotype and sphere-forming capacity.	ALDH1A2 ALDH1A3	2.21e-05	3	95	2	24884875
Pubmed	Structural and kinetic features of aldehyde dehydrogenase 1A (ALDH1A) subfamily members, cancer stem cell markers active in retinoic acid biosynthesis.	ALDH1A2 ALDH1A3	2.21e-05	3	95	2	31923393
Pubmed	BS69 negatively regulates the canonical NF-kappaB activation induced by Epstein-Barr virus-derived LMP1.	ZMYND11 PDLIM7	2.21e-05	3	95	2	19379743
Pubmed	Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration.	ALDH1A2 ALDH1A3	2.21e-05	3	95	2	35315776
Pubmed	Mining distinct aldehyde dehydrogenase 1 (ALDH1) isoenzymes in gastric cancer.	ALDH1A2 ALDH1A3	2.21e-05	3	95	2	27015121
Pubmed	Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse.	ALDH1A2 ALDH1A3	2.21e-05	3	95	2	11744377
Pubmed	Induction of human ADAMTS-2 gene expression by IL-1α is mediated by a multiple crosstalk of MEK/JNK and PI3K pathways in osteoblast like cells.	ADAMTS3 ADAMTS2	2.21e-05	3	95	2	26232334
Pubmed	Identification of active retinaldehyde dehydrogenase isoforms in the postnatal human eye.	ALDH1A2 ALDH1A3	2.21e-05	3	95	2	25793304
Pubmed	IL-6 upregulates a disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS-2) in human osteosarcoma cells mediated by JNK pathway.	ADAMTS3 ADAMTS2	2.21e-05	3	95	2	24752352
Pubmed	Concerted action of aldehyde dehydrogenases influences depot-specific fat formation.	ALDH1A2 ALDH1A3	2.21e-05	3	95	2	21436255
Pubmed	An IRBIT homologue lacks binding activity to inositol 1,4,5-trisphosphate receptor due to the unique N-terminal appendage.	AHCYL1 AHCYL2	2.21e-05	3	95	2	19220705
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	COL4A1 FBLN2 ADAMTS3 TNXB	2.93e-05	64	95	4	22261194
Pubmed	Glutamate can act as a signaling molecule in mouse preimplantation embryos†.	GRIN2B GRM4 GRM6	3.83e-05	24	95	3	35746896
Pubmed	Nature and the multiple functions of the 67-kD elastin-/laminin binding protein.	COL4A1 COL4A4	4.41e-05	4	95	2	7827955
Pubmed	Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion.	RHOD ARHGAP35	4.41e-05	4	95	2	18829532
Pubmed	Dynamic expression of the retinoic acid-synthesizing enzyme retinol dehydrogenase 10 (rdh10) in the developing mouse brain and sensory organs.	ALDH1A2 ALDH1A3	4.41e-05	4	95	2	18399539
Pubmed	RhoD binds the Rab5 effector Rabankyrin-5 and has a role in trafficking of the platelet-derived growth factor receptor.	RHOD RHOF	4.41e-05	4	95	2	24102721
Pubmed	Astrocytes as a regulated source of retinoic acid for the brain.	ALDH1A2 ALDH1A3	4.41e-05	4	95	2	22930583
Pubmed	P190A RhoGAP is required for mammary gland development.	ARHGAP5 ARHGAP35	4.41e-05	4	95	2	21945077
Pubmed	Sex-specific timing of meiotic initiation is regulated by Cyp26b1 independent of retinoic acid signalling.	ALDH1A2 ALDH1A3	4.41e-05	4	95	2	21224842
Pubmed	Characterization of cardiac-resident progenitor cells expressing high aldehyde dehydrogenase activity.	ALDH1A2 ALDH1A3	4.41e-05	4	95	2	23484127
Pubmed	The NHERF1 PDZ1 domain and IRBIT interact and mediate the activation of Na+/H+ exchanger 3 by ANG II.	AHCYL1 SLC9A3	4.41e-05	4	95	2	27279487
Pubmed	Two functionally redundant sources of retinoic acid secure spermatogonia differentiation in the seminiferous epithelium.	ALDH1A2 ALDH1A3	4.41e-05	4	95	2	30487180
Pubmed	VEGF-A stimulates podosome-mediated collagen-IV proteolysis in microvascular endothelial cells.	COL4A1 ARHGAP5	4.41e-05	4	95	2	27231093
Pubmed	Distribution of group-III metabotropic glutamate receptors in the retina.	GRM4 GRM6	4.41e-05	4	95	2	17311335
Pubmed	Elevated gene expression of glutamate receptors in noradrenergic neurons from the locus coeruleus in major depression.	GRIN2B GRM4	4.41e-05	4	95	2	24925192
Pubmed	Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis.	ALDH1A2 ALDH1A3	4.41e-05	4	95	2	23012458
Pubmed	ADAMTS: a novel family of proteases with an ADAM protease domain and thrombospondin 1 repeats.	ADAMTS3 ADAMTS2	4.41e-05	4	95	2	10094461
Pubmed	Expression of ADAMTS-2, -3, -13, and -14 in culprit coronary lesions in patients with acute myocardial infarction or stable angina.	ADAMTS3 ADAMTS2	4.41e-05	4	95	2	22205175
Pubmed	Non-cell-autonomous retinoid signaling is crucial for renal development.	ALDH1A2 ALDH1A3	4.41e-05	4	95	2	20040494
Pubmed	Genome-scale RNAi screen for host factors required for HIV replication.	JAK1 RHOD GRIN2B BCAS1 PGK2 PPM1N MYLK2	6.19e-05	361	95	7	18976975
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	COL4A1 THSD4 COL4A4 FBLN2	6.71e-05	79	95	4	18757743
Pubmed	Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice.	ALDH1A2 ALDH1A3	7.34e-05	5	95	2	11959834
Pubmed	In vitro interactions of oxidatively modified LDL with type I, II, III, IV, and V collagen, laminin, fibronectin, and poly-D-lysine.	COL4A1 COL4A4	7.34e-05	5	95	2	9409248
Pubmed	[ADAMTS family--new extracellular matrix degrading enzyme].	ADAMTS3 ADAMTS2	7.34e-05	5	95	2	11831030
Pubmed	Retinoic acid signaling is directly activated in cardiomyocytes and protects mouse hearts from apoptosis after myocardial infarction.	ALDH1A2 ALDH1A3	7.34e-05	5	95	2	34623260
Pubmed	Glucose metabolism gene polymorphisms and clinical outcome in pancreatic cancer.	HK2 GFPT1	7.34e-05	5	95	2	20845477
Pubmed	Multiple members of a third subfamily of P-type ATPases identified by genomic sequences and ESTs.	ATP9B ATP9A	7.34e-05	5	95	2	9548971
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	AHCYL1 AAAS WAPL HK2 SPOUT1 PDLIM7 EIF2B3 FAM98A HERC2 WDR1 DNAJA1 GFPT1 EXOC4	7.95e-05	1353	95	13	29467282
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	COL4A1 FBLN2 COL16A1 TNXB	9.34e-05	86	95	4	28327460
Pubmed	Regulation of MAGE-A3/6 by the CRL4-DCAF12 ubiquitin ligase and nutrient availability.	HK2 WDR1 FLG2 MYLK2	1.07e-04	89	95	4	31267705
Pubmed	Pias1 interaction and sumoylation of metabotropic glutamate receptor 8.	GRM4 GRM6	1.10e-04	6	95	2	16144832
Pubmed	Stimulation of extracellular matrix components in the normal brain by invading glioma cells.	COL4A1 COL4A4	1.10e-04	6	95	2	9506531
Pubmed	HIV-1 gp160 protein-macrophage interactions modulate mesangial cell proliferation and matrix synthesis.	COL4A1 COL4A4	1.10e-04	6	95	2	7495302
Pubmed	NMDA receptor trafficking through an interaction between PDZ proteins and the exocyst complex.	GRIN2B EXOC4	1.10e-04	6	95	2	12738960
Pubmed	Extracellular matrix of the human optic nerve head.	COL4A1 COL4A4	1.10e-04	6	95	2	2426947
Pubmed	Targeted disruption of Aldh1a1 (Raldh1) provides evidence for a complex mechanism of retinoic acid synthesis in the developing retina.	ALDH1A2 ALDH1A3	1.10e-04	6	95	2	12808103
Pubmed	Retinoic acid regulates olfactory progenitor cell fate and differentiation.	ALDH1A2 ALDH1A3	1.10e-04	6	95	2	23829703
Pubmed	Angiogenesis and collagen type IV expression in different endothelial cell culture systems.	COL4A1 COL4A4	1.10e-04	6	95	2	23551189
Pubmed	Monoclonal antibody to human basement membrane collagen type IV.	COL4A1 COL4A4	1.10e-04	6	95	2	6811420
Pubmed	Dynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear.	ALDH1A2 ALDH1A3	1.10e-04	6	95	2	16615129
Pubmed	Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas.	COL4A1 COL4A4	1.10e-04	6	95	2	6389236
Pubmed	Collagen IV in the developing lens capsule.	COL4A1 COL4A4	1.10e-04	6	95	2	12225806
Pubmed	Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.	COL4A1 COL4A4	1.10e-04	6	95	2	10534397
Pubmed	A tumor derived motility factor that stimulates cell migration on extracellular matrix.	COL4A1 COL4A4	1.10e-04	6	95	2	9673377
Pubmed	A retinoic acid synthesizing enzyme in ventral retina and telencephalon of the embryonic mouse.	ALDH1A2 ALDH1A3	1.10e-04	6	95	2	10906479
Pubmed	Regulation of procollagen amino-propeptide processing during mouse embryogenesis by specialization of homologous ADAMTS proteases: insights on collagen biosynthesis and dermatosparaxis.	ADAMTS3 ADAMTS2	1.10e-04	6	95	2	16556917
Pubmed	Localization of type IV collagen a 1 to a 6 chains in basement membrane during mouse molar germ development.	COL4A1 COL4A4	1.10e-04	6	95	2	11732842
Pubmed	DLG1 influences distal ureter maturation via a non-epithelial cell autonomous mechanism involving reduced retinoic acid signaling, Ret expression, and apoptosis.	ALDH1A2 ALDH1A3	1.10e-04	6	95	2	24699546
Pubmed	Tripartite Motif-containing 33 (TRIM33) protein functions in the poly(ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein.	TRIM33 APLF	1.10e-04	6	95	2	23926104
Pubmed	Developmental distribution of collagen IV isoforms and relevance to ocular diseases.	COL4A1 COL4A4	1.10e-04	6	95	2	19275937
Pubmed	The bacterial virulence factor lymphostatin compromises intestinal epithelial barrier function by modulating rho GTPases.	RHOD RHOF	1.10e-04	6	95	2	19286565
Pubmed	Distribution of basement membrane proteins in normal and fibrotic human liver: collagen type IV, laminin, and fibronectin.	COL4A1 COL4A4	1.10e-04	6	95	2	6988303
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	ARHGAP5 ALDH1A2 IGF2R PDLIM7 SNX18 HERC2 LCP1 DNAJA1 GFPT1 EXOC4	1.15e-04	853	95	10	28718761
Pubmed	Genome-wide association study of selenium concentrations.	TXNRD1 DCUN1D5 IRX2	1.21e-04	35	95	3	25343990
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL4A1 COL4A4 FBLN2 COL16A1 TNXB	1.22e-04	175	95	5	28071719
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	TRIM33 AHCYL1 AAAS CEP78 PRICKLE3 PDLIM7 EIF2B3 SNX18 AHCYL2 UPF3A RHOF	1.26e-04	1038	95	11	26673895
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	TRIM33 CUL9 MIB2 HERC2	1.37e-04	95	95	4	29643511
Pubmed	Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo.	COL4A1 COL4A4	1.54e-04	7	95	2	10639489
Pubmed	Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M.	COL4A1 COL4A4	1.54e-04	7	95	2	11711546
Pubmed	Lsh, an epigenetic guardian of repetitive elements.	IGF2R PGK2	1.54e-04	7	95	2	15448183
Pubmed	Regulation of protease nexin-1 target protease specificity by collagen type IV.	COL4A1 COL4A4	1.54e-04	7	95	2	8006028
Pubmed	Transforming Growth Factor-beta signaling in αβ thymocytes promotes negative selection.	TRIM33 AIRE	1.54e-04	7	95	2	31857584
Pubmed	Positive association between ALDH1A2 and schizophrenia in the Chinese population.	ALDH1A2 ALDH1A3	1.54e-04	7	95	2	19703508
Pubmed	Corneal cell proteins and ocular surface pathology.	COL4A1 COL4A4	1.54e-04	7	95	2	10416788
Pubmed	Retinoic acid signaling is dispensable for somatic development and function in the mammalian ovary.	ALDH1A2 ALDH1A3	1.54e-04	7	95	2	28274610
Pubmed	The 8-kDa dynein light chain binds to its targets via a conserved (K/R)XTQT motif.	ZMYND11 BCAS1	1.54e-04	7	95	2	11148209
Pubmed	Hypoplastic basement membrane of the lens anlage in the inheritable lens aplastic mouse (lap mouse).	COL4A1 COL4A4	1.54e-04	7	95	2	10716744
Pubmed	Purification, partial characterization of rat kidney hyaluronic acid binding protein and its localization on the cell surface.	COL4A1 COL4A4	1.54e-04	7	95	2	1724753
Pubmed	Metabotropic glutamate receptor subtype 7 ablation causes deficit in fear response and conditioned taste aversion.	GRM4 GRM6	1.54e-04	7	95	2	9920659
Cytoband	2p13	HK2 GFPT1	1.04e-03	23	95	2	2p13
Cytoband	20q13.2	BCAS1 ATP9A	1.44e-03	27	95	2	20q13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr5q35	ADAMTS2 PDLIM7 DOK3 GRM6	1.48e-03	235	95	4	chr5q35
GeneFamily	Rho family GTPases	RHOD RHOV RHOF	4.41e-05	20	63	3	390
GeneFamily	Glutamate metabotropic receptors\|Protein phosphatase 1 regulatory subunits	GRM4 GRM6	3.30e-04	8	63	2	281
GeneFamily	Collagens	COL4A1 COL4A4 COL16A1	5.50e-04	46	63	3	490
GeneFamily	ATPase phospholipid transporting	ATP9B ATP9A	1.22e-03	15	63	2	1210
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	MIB2 HERC2	1.76e-03	18	63	2	91
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS3 ADAMTS2	1.97e-03	19	63	2	50
GeneFamily	Aldehyde dehydrogenases	ALDH1A2 ALDH1A3	1.97e-03	19	63	2	398
GeneFamily	PHD finger proteins	TRIM33 ZMYND11 AIRE	3.82e-03	90	63	3	88
Coexpression	NABA_CORE_MATRISOME	COL4A1 THSD4 COL4A4 FBLN2 COL16A1 IMPG1 OTOL1 TNXB	5.92e-06	270	94	8	MM17057
Coexpression	NABA_CORE_MATRISOME	COL4A1 THSD4 COL4A4 FBLN2 COL16A1 IMPG1 OTOL1 TNXB	6.77e-06	275	94	8	M5884
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 COL4A4 ALDH1A2 FBLN2 IMPG1 PPM1N MYLK2	1.11e-07	178	95	7	a107dd98a07086ed0429116095ecda60c9dbef1e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 THSD4 COL4A4 COL16A1 ADAMTS2 HSD17B2 TNXB	2.06e-07	195	95	7	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 THSD4 COL4A4 COL16A1 ADAMTS2 HSD17B2 TNXB	2.06e-07	195	95	7	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 THSD4 COL16A1 ADAMTS2 PDLIM7 HSD17B2 TNXB	2.14e-07	196	95	7	2b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4\|TCGA-Lung / Sample_Type by Project: Shred V9	COL4A1 ZNF469 FBLN2 COL16A1 ADAMTS2 OTOL1	1.64e-06	168	95	6	aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A4 FBLN2 PTGR1 THSD7B ALDH1A3 TNXB	3.04e-06	187	95	6	fa8f221b4c2df61eadaa9c77e4cf45848b00330b
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ALDH1A2 FBLN2 ADAMTS3 ADAMTS2 ALDH1A3 TNXB	3.33e-06	190	95	6	0fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FBLN2 COL16A1 ADAMTS2 ALDH1A3 MN1 TNXB	3.54e-06	192	95	6	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 ALDH1A2 FBLN2 COL16A1 ADAMTS2 TNXB	3.54e-06	192	95	6	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 ALDH1A2 FBLN2 COL16A1 ADAMTS2 TNXB	3.54e-06	192	95	6	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	FBLN2 COL16A1 ADAMTS2 ALDH1A3 MN1 TNXB	3.54e-06	192	95	6	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 ALDH1A2 FBLN2 HK2 ADAMTS2 TNXB	3.54e-06	192	95	6	2d9e2262f1342fe17735f21f733c029d1275e955
ToppCell	droplet-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 THSD4 ALDH1A2 HK2 ADAM23 DNAJA1	3.65e-06	193	95	6	2d891c00b8f0aace17d4c300b63e2341dcffa199
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ZNF469 ALDH1A2 FBLN2 COL16A1 ADAMTS2 MN1	3.65e-06	193	95	6	adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ALDH1A2 FBLN2 ADAMTS2 ADAM23 MN1 TNXB	3.65e-06	193	95	6	025836c5c5a711e477c326559e618e47cae42d11
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A1 COL16A1 ADAMTS3 ALDH1A3 MN1 TNXB	3.65e-06	193	95	6	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 ALDH1A2 FBLN2 HK2 ADAMTS2 TNXB	3.65e-06	193	95	6	45b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCell	facs-Bladder-nan-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 THSD4 ALDH1A2 HK2 ADAM23 DNAJA1	3.76e-06	194	95	6	f4c9fc53ae31d58096906d9305b0b4082512a7e9
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ALDH1A2 FBLN2 ADAMTS2 ALDH1A3 MN1 TNXB	3.76e-06	194	95	6	5594f7437448cb4b37d2d100f44d30c4a367df26
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 THSD4 ALDH1A2 HK2 COL16A1 ADAM23	3.76e-06	194	95	6	ee6b5fb4e993a4c0dc556091b8fefd56bdc70d8f
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 THSD4 ALDH1A2 HK2 COL16A1 ADAM23	3.87e-06	195	95	6	841fde528ecb293e07b5e00e499d1e9f0b0dce14
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 THSD4 COL16A1 ADAMTS2 ADAM23 TNXB	3.87e-06	195	95	6	223f5f07dc28fa13a09bb589884c58043c7928c7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 THSD4 COL16A1 ADAMTS2 PDLIM7 TNXB	3.99e-06	196	95	6	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 THSD4 COL16A1 ADAMTS2 PDLIM7 TNXB	3.99e-06	196	95	6	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	droplet-Bladder-nan-3m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 THSD4 ALDH1A2 COL16A1 ADAMTS2 ADAM23	3.99e-06	196	95	6	f47e551ba484687ba6ce8c29a085106131364042
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 THSD4 ALDH1A2 COL16A1 ADAMTS2 ADAM23	4.11e-06	197	95	6	86145bc1e585b4ae136e755cafd6579da2abfa65
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 THSD4 COL16A1 ADAMTS2 PDLIM7 HSD17B2	4.11e-06	197	95	6	80e153790cef37b743e22a7370ff5b3a6abf147d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ALDH1A2 FBLN2 RHOD ADAMTS2 ALDH1A3 FLG2	4.35e-06	199	95	6	dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ALDH1A2 FBLN2 RHOD ADAMTS2 ALDH1A3 FLG2	4.35e-06	199	95	6	c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	COL4A4 FBXO24 ALDH1A2 RHOD TNXB	6.18e-06	121	95	5	5035e071033cb76a7fc0128716755b14821e8f05
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	COL4A4 FBXO24 ALDH1A2 RHOD TNXB	6.18e-06	121	95	5	c96115bd33455296378a257583b49442d00b39ca
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FBLN2 AIRE DGKG BCAS1 ALDH1A3	2.05e-05	155	95	5	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL4A1 THSD4 SOX11 PDLIM7 PRSS42P	2.18e-05	157	95	5	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 THSD4 GRIN2B TNXB MYLK2	2.85e-05	166	95	5	5ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 THSD4 GRIN2B TNXB MYLK2	2.85e-05	166	95	5	6bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 ALDH1A2 FAM98A TNXB MYLK2	2.94e-05	167	95	5	784776d1fcc098f84d3c2eca58fa56cb9428f434
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 THSD4 ADAMTS2 PDLIM7 TNXB	3.20e-05	170	95	5	fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 THSD4 ADAMTS2 PDLIM7 TNXB	3.20e-05	170	95	5	03044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AHCYL1 SLC9A3 ALDH1A2 IRX2 C4orf54	3.47e-05	173	95	5	7a3115e7cf7e2f345192cde0656a7f0193594a5f
ToppCell	AT1-AT2_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	COL4A1 THSD4 COL4A4 XAGE2 IRX2	3.67e-05	175	95	5	bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 THSD4 COL4A4 COL16A1 ADAMTS2	3.77e-05	176	95	5	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 THSD4 COL4A4 COL16A1 ADAMTS2	3.77e-05	176	95	5	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHOD C11orf54 AHCYL2 HSD17B2 RHOF	3.77e-05	176	95	5	7622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ALDH1A2 COL16A1 ADAMTS3 ADAMTS2 TNXB	4.20e-05	180	95	5	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	COL4A1 THSD4 PDLIM7 DGKG THSD7B	4.20e-05	180	95	5	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	facs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 THSD4 ALDH1A2 ADAM23 MYLK2	4.20e-05	180	95	5	12537d8a569faa69f474284d2c201475722b8ca1
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ALDH1A2 COL16A1 ADAMTS3 ADAMTS2 TNXB	4.20e-05	180	95	5	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A4 ALDH1A2 FBLN2 IMPG1 PPM1N	4.42e-05	182	95	5	9966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBLN2 RHOD ADAMTS2 ALDH1A3 MN1	4.66e-05	184	95	5	d754c3de621429b220ae4ac426cdfc619e848462
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 FBLN2 ADAMTS3 ADAMTS2 TNXB	4.78e-05	185	95	5	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	FBLN2 COL16A1 ADAMTS2 ALDH1A3 TNXB	4.78e-05	185	95	5	506eee2c1b6e8acec3aa8b2c66868010006c4c14
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNRD1 COL4A1 SOX11 ARHGAP5 AHCYL1	4.78e-05	185	95	5	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN2 COL16A1 ADAMTS2 ALDH1A3 TNXB	5.16e-05	188	95	5	c32d023a69b6da79687ff8fa7485e7499db57046
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ABAT ZNF469 IGF2R ALDH1A3 ATP9A	5.16e-05	188	95	5	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	FBLN2 COL16A1 ADAMTS3 MN1 TNXB	5.16e-05	188	95	5	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN2 COL16A1 ADAMTS2 ALDH1A3 TNXB	5.16e-05	188	95	5	1cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A4 FBLN2 ADAMTS2 MN1 TNXB	5.16e-05	188	95	5	bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 ADAMTS2 ADAM23 ALDH1A3 TNXB	5.29e-05	189	95	5	544d95df910f1b276995624509a7e41b219baca0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 COL4A4 COL16A1 ADAMTS2 TNXB	5.29e-05	189	95	5	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALDH1A2 FBLN2 ADAMTS2 MN1 TNXB	5.29e-05	189	95	5	f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 COL4A4 COL16A1 ADAMTS2 TNXB	5.29e-05	189	95	5	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	facs-BAT-Fat-18m-Mesenchymal\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 FBLN2 ADAMTS2 ADAM23 TNXB	5.29e-05	189	95	5	bba28f57a0708515fdd5acd9592dbbe4a4f57116
ToppCell	facs-BAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 FBLN2 ADAMTS2 ADAM23 TNXB	5.29e-05	189	95	5	cf293b23a4c0e8a0c9f09115b1d53d9b11de72e2
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALDH1A2 FBLN2 HK2 SNX18 TNXB	5.29e-05	189	95	5	6e52cac679e0541ca5f2be316bdabdbc34da6e18
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|Epithelial / Disease state, Lineage and Cell class	COL4A1 COL4A4 SOX11 RHOD PDLIM7	5.29e-05	189	95	5	4178be3292ff4a8a1d8098f638d4b8d15164d2c6
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALDH1A2 FBLN2 ADAMTS2 MN1 TNXB	5.29e-05	189	95	5	378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SLC9A3 ALDH1A2 KCTD16 EXOC4	5.29e-05	189	95	5	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	facs-BAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 FBLN2 ADAMTS2 ADAM23 TNXB	5.29e-05	189	95	5	87323e86a5b5d159920a07e6bd7ef5e3438cd085
ToppCell	MatrixFB-Fibroblast-C\|MatrixFB / shred on cell class and cell subclass (v4)	COL4A4 ALDH1A2 FBLN2 ADAMTS2 TNXB	5.43e-05	190	95	5	d0106f7a21292f0b96ce4337ec3efbb1bd78dd0a
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 FBLN2 HK2 ADAMTS2 TNXB	5.43e-05	190	95	5	bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 FBLN2 HK2 ADAMTS2 TNXB	5.43e-05	190	95	5	e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ALDH1A2 COL16A1 ADAMTS2 MN1 TNXB	5.43e-05	190	95	5	947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 FBLN2 HK2 ADAMTS2 TNXB	5.43e-05	190	95	5	ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCell	droplet-Limb_Muscle\|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TXNRD1 COL4A1 FBLN2 DNAJA1 TNXB	5.43e-05	190	95	5	06c2b13fa88abbcb8086f13b8d98a156e41e4198
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 ADAMTS2 SNX18 TNXB MYLK2	5.43e-05	190	95	5	7df63e5e0dd395676f4fc18cad0d8b2428390943
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	COL4A1 COL16A1 ADAMTS2 KCTD16 TNXB	5.43e-05	190	95	5	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 ADAMTS2 SNX18 TNXB MYLK2	5.43e-05	190	95	5	140aca04c044cd7a93f81ff1631b00b5216d2cb1
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ALDH1A2 FBLN2 COL16A1 ADAMTS2 MN1	5.43e-05	190	95	5	4f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 FBLN2 HK2 ADAMTS2 TNXB	5.43e-05	190	95	5	47077579496c5340e99f61499427a3a36b566da3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 COL4A4 COL16A1 ADAMTS2 TNXB	5.56e-05	191	95	5	a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ALDH1A2 FBLN2 ADAMTS2 MN1 TNXB	5.56e-05	191	95	5	2b73fcd592d16cae8ded5e45c8fbf2d9adc8caad
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBXO24 COL16A1 THSD7B MN1 TNXB	5.56e-05	191	95	5	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 FBLN2 HK2 ADAMTS2 TNXB	5.56e-05	191	95	5	a57cf0519d749febc0b69fe0b098b7ba53d63258
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZNF469 ALDH1A2 FBLN2 COL16A1 ADAMTS2	5.56e-05	191	95	5	4b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 COL4A4 COL16A1 ADAMTS2 TNXB	5.56e-05	191	95	5	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 FBLN2 HK2 ADAMTS2 TNXB	5.56e-05	191	95	5	19c67a812b8ce97472d316acd15aeefe8736000d
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ALDH1A2 COL16A1 RHOD GRIN2B MN1	5.56e-05	191	95	5	156b467187331ac6ca390d6ca861d9670bb7b956
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ALDH1A2 COL16A1 ADAMTS2 MN1 TNXB	5.56e-05	191	95	5	db4943dd19207663fb9e27f8940fa4b06a933625
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZNF469 ALDH1A2 FBLN2 COL16A1 ADAMTS2	5.56e-05	191	95	5	75d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ALDH1A2 COL16A1 ADAMTS2 SNX18 TNXB	5.56e-05	191	95	5	9f478f36a0b895e607e3bb77fa0f9f03cc0f33fc
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 HK2 ADAMTS2 MN1 TNXB	5.56e-05	191	95	5	1b26056df078674f37a6c06f6256b30cfcec21a7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 COL4A4 COL16A1 ADAMTS2 TNXB	5.56e-05	191	95	5	8f6d592edc32fdb901af30501d4360512334e8c2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 COL4A4 COL16A1 ADAMTS2 HSD17B2	5.70e-05	192	95	5	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 COL4A4 COL16A1 ADAMTS2 TNXB	5.70e-05	192	95	5	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ALDH1A2 FBLN2 ADAMTS2 MN1 TNXB	5.70e-05	192	95	5	c3707243c5590d852c9f28429c96f50a1fa6b0dc
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 COL16A1 ADAMTS2 MN1 TNXB	5.70e-05	192	95	5	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALDH1A2 FBLN2 COL16A1 ADAMTS2 TNXB	5.70e-05	192	95	5	8937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ALDH1A2 FBLN2 ADAMTS2 MN1 TNXB	5.70e-05	192	95	5	0e7e55505bd5454d7cf952a63fdcb46ec76f1973
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 COL4A4 COL16A1 ADAMTS2 HSD17B2	5.70e-05	192	95	5	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	TXNRD1 COL4A1 COL4A4 FBLN2 TNXB	5.70e-05	192	95	5	356160b113c3305a61ceeaff33ce3c9da0be2878
Disease	waist-hip ratio	PPP1R3A COL4A1 THSD4 TRIM33 ZMYND11 DCUN1D5 ADAMTS2 ADAM23 SHMT1 DGKG CUL9 GRIN2B LCP1 MN1 ZMYM4 MYLK2	8.47e-07	1226	90	16	EFO_0004343
Disease	cesarean section, Self-injurious behavior	ALDH1A2 LCP1 EXOC4	1.28e-04	32	90	3	EFO_0009636, HP_0100716
Disease	intraocular pressure measurement	COL4A1 SOX11 ZNF469 COL16A1 ADAMTS2 DGKG HERC2 TNXB	1.67e-04	509	90	8	EFO_0004695
Disease	fish oil supplement exposure measurement, high density lipoprotein cholesterol measurement	LCP1 GRM4	1.91e-04	7	90	2	EFO_0004612, EFO_0600007
Disease	cholesteryl esters to total lipids in medium LDL percentage	ALDH1A2 IGF2R LCP1	1.98e-04	37	90	3	EFO_0022252
Disease	triglycerides in large LDL measurement	ALDH1A2 IGF2R LCP1	3.10e-04	43	90	3	EFO_0022319
Disease	Ehlers-Danlos syndrome (is_implicated_in)	ADAMTS2 TNXB	3.27e-04	9	90	2	DOID:13359 (is_implicated_in)
Disease	corneal topography	ZNF469 FBLN2 ADAMTS3 LINC02902	3.53e-04	109	90	4	EFO_0004345
Disease	anti-thyroglobulin antibody measurement	JAK1 SLC9A3 BCAS1	3.79e-04	46	90	3	EFO_0009896
Disease	myopathy (implicated_via_orthology)	COL4A1 COL4A4 PDLIM7	4.30e-04	48	90	3	DOID:423 (implicated_via_orthology)
Disease	vitamin D measurement, COVID-19	ALDH1A2 ADAMTS3 BCAS1	4.57e-04	49	90	3	EFO_0004631, MONDO_0100096
Disease	glycerophosphorylcholine measurement	JAK1 GRIN2B	4.97e-04	11	90	2	EFO_0020018
Disease	phospholipids in medium VLDL measurement	ALDH1A2 IGF2R LCP1	5.44e-04	52	90	3	EFO_0022154
Disease	cholesterol in small VLDL measurement	ALDH1A2 IGF2R LCP1	5.76e-04	53	90	3	EFO_0022228
Disease	collagen disease (implicated_via_orthology)	COL4A1 COL4A4	5.95e-04	12	90	2	DOID:854 (implicated_via_orthology)
Disease	triglycerides in LDL measurement	ALDH1A2 IGF2R LCP1	6.77e-04	56	90	3	EFO_0022320
Disease	triglycerides in IDL measurement	ALDH1A2 IGF2R LCP1	7.50e-04	58	90	3	EFO_0022149
Disease	phospholipids in VLDL measurement	ALDH1A2 IGF2R LCP1	7.88e-04	59	90	3	EFO_0022301
Disease	cholesterol efflux capacity measurement	ALDH1A2 LCP1	8.17e-04	14	90	2	EFO_0009132
Disease	Childhood Ataxia with Central Nervous System Hypomyelinization	COL4A1 EIF2B3	8.17e-04	14	90	2	C1858991
Disease	total lipids in VLDL measurement	ALDH1A2 IGF2R LCP1	8.28e-04	60	90	3	EFO_0022314
Disease	free cholesterol in VLDL measurement	ALDH1A2 IGF2R LCP1	8.69e-04	61	90	3	EFO_0022276
Disease	triglycerides in medium LDL measurement	ALDH1A2 IGF2R LCP1	9.11e-04	62	90	3	EFO_0022322
Disease	low density lipoprotein triglyceride measurement	ALDH1A2 LCP1	9.41e-04	15	90	2	EFO_0009946
Disease	level of Triacylglycerol (53:3) in blood serum	ALDH1A2 LCP1	9.41e-04	15	90	2	OBA_2045165
Disease	stroke	COL4A1 ALDH1A2 ADAMTS2 C4orf54	1.00e-03	144	90	4	EFO_0000712
Disease	total lipids in small VLDL	ALDH1A2 IGF2R LCP1	1.14e-03	67	90	3	EFO_0022148
Disease	triglycerides in very small VLDL measurement	ALDH1A2 IGF2R LCP1	1.19e-03	68	90	3	EFO_0022144
Disease	level of Sphingomyelin (d34:1) in blood serum	ALDH1A2 ADAMTS3	1.36e-03	18	90	2	OBA_2045175
Disease	very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	ALDH1A2 LCP1	1.36e-03	18	90	2	EFO_0008317, EFO_0008589
Disease	esterified cholesterol measurement, high density lipoprotein cholesterol measurement	ALDH1A2 LCP1	1.52e-03	19	90	2	EFO_0004612, EFO_0008589
Disease	neuroimaging measurement	THSD4 JAK1 SOX11 ZNF469 ALDH1A2 ADAMTS3 FAM98A WDR1 ARHGAP35 EXOC4	1.55e-03	1069	90	10	EFO_0004346
Disease	monounsaturated fatty acids; 16:1, 18:1 measurement	ALDH1A2 IGF2R LCP1	1.77e-03	78	90	3	EFO_0022187
Disease	phosphatidylcholine measurement	ALDH1A2 ADAMTS2 THSD7B LCP1 TNXB	1.80e-03	284	90	5	EFO_0010226
Disease	free cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	ALDH1A2 LCP1	1.86e-03	21	90	2	EFO_0022277
Disease	docosahexaenoic acid to total fatty acids percentage	ALDH1A2 LCP1	1.86e-03	21	90	2	EFO_0022262
Disease	Huntington's disease (is_implicated_in)	ABAT GRIN2B	2.23e-03	23	90	2	DOID:12858 (is_implicated_in)
Disease	serum metabolite measurement	COL4A4 SLC9A3 ALDH1A2 IGF2R LINC02902 BCAS1 WDR1 LCP1 PGK2	2.38e-03	945	90	9	EFO_0005653
Disease	linoleic acid measurement	ALDH1A2 IGF2R THSD7B LCP1	2.56e-03	186	90	4	EFO_0006807
Disease	age-related macular degeneration	ALDH1A2 HERC2 TNXB	2.58e-03	89	90	3	EFO_0001365
Disease	dental caries	THSD4 ADAMTS3 ADAMTS2 AIRE	2.61e-03	187	90	4	EFO_0003819
Disease	cholesteryl ester measurement, intermediate density lipoprotein measurement	ALDH1A2 IGF2R LCP1	3.01e-03	94	90	3	EFO_0008595, EFO_0010351

Protein segments in the cluster

Peptide	Gene	Start	Entry
KGCVGGAKSATIVAD	AAAS	366	Q9NRG9
NTEGTEKGNCGKDGD	ADAM23	631	O75077
SGGNVIQGSGKEEIC	APLF	206	Q8IW19
KVSVCGAGFDLEGGK	CXorf49;	6	A8MYA2
QSGVAEGAKLECGGK	ALDH1A2	376	O94788
QCAEGPKGEKGESGA	COL16A1	371	Q07092
LIEKDGTEVRCGSGG	GRM4	126	Q14833
SGKKEGAKLECGGSA	ALDH1A3	371	P47895
GPKGEKGNEGLCACE	COL4A4	481	P53420
DGLKGQKGDTISCNV	COL4A4	656	P53420
GDGGLEIICQGIKSS	CEP78	161	Q5JTW2
NVICDKCEGRGGKKG	DNAJA1	131	P31689
GVAAAVAEDGGLKKC	DCUN1D5	11	Q9BTE7
KVGCDGVIGSSKQED	ADAMTS2	696	O95450
ESGGSKKCIQVGGEF	AIRE	216	O43918
EIGEKGQKGESCLIC	COL4A1	456	P02462
KATSKGCITVIGGGD	PGK2	361	P07205
VEIVATDGGGLSGKC	PCDHB5	316	Q9Y5E4
KGICTEDGGNGIKLI	JAK1	941	P23458
GGEGPQCEKTTDVKK	HPF1	11	Q9NWY4
QDGECGTLSKGELKE	FLG2	21	Q5D862
CCKNGKGDKEGESGT	KCTD16	291	Q68DU8
KGLKVIDVACGSGDA	HERC2	601	O95714
GPGTKECEVLQGKGA	IMPG1	731	Q17R60
DCGIGIEGKEGKQAS	ATP9B	886	O43861
IARNKGVVLGGCGDK	ABAT	456	P80404
KGFKASGCEGEDVVT	HK2	621	P52789
AGVLGAKEGETCGAE	FBLN2	491	P98095
KKEGICAIGGTSEQS	LCP1	96	P13796
NSKEALGGGKFGAVC	MYLK2	286	Q9H1R3
QVSEECGEKGQDGAG	PPM1N	401	Q8N819
DGGTGSGQKGKCEEF	DOK3	21	Q7L591
TGKLTCAVGDGGNDV	ATP9A	776	O75110
SDCGVGVEGKEGKQA	ATP9A	796	O75110
GKCKGLLGGGVSVED	CFP	41	P27918
CGKVLEEGGFFEEKG	PDLIM7	311	Q9NR12
EPKKDASEGCTVVGG	IRX2	451	Q9BZI1
GTPLKKDGEECTNEG	PROSER1	161	Q86XN7
KDGEECTNEGKGIAA	PROSER1	166	Q86XN7
EGGAKNIEVKDLGCL	PPP1R3A	471	Q16821
CEECGKQIGGGDIAV	PRICKLE3	186	O43900
AKDGGGLSGKCTVVV	PCDHB7	321	Q9Y5E2
RSVKVVLVGDGGCGK	RHOD	16	O00212
PGEKSDGCVSAKGEL	DGKG	406	P49619
EKGADIKDCLIGSGQ	EIF2B3	416	Q9NR50
DDNLIEGGGTKFVCK	EXOC4	476	Q96A65
RGECVKVGCDKEIGS	ADAMTS3	681	O15072
NKVEDKCGVCGGDNS	ADAMTS3	696	O15072
QGKDGVALKCEESGK	IDNK	96	Q5T6J7
GAAGRACGQLKKEQG	GRM6	51	O15303
CGITLEKAGGLEDTG	LINC02902	91	Q6ZTY9
TLGVETCGSKGNAEK	C17orf80	301	Q9BSJ5
CGSELGVEEKRGKGN	FBXO24	21	O75426
KCGEVGKVGVEEGKA	CUL9	46	Q8IWT3
GKEEACEGTCGQAKI	FDXACB1	331	Q9BRP7
GKEKEGQELGTADCS	BCAS1	246	O75363
ESEGCQAVGGEGEKI	C4orf54	311	D6RIA3
DQKAVLVTGGDCGLG	HSD17B2	81	P37059
EGEFTGVGKKGQACV	SPOUT1	126	Q5T280
EKCSAGSQKAGSGEG	IRGQ	371	Q8WZA9
KGDTCGNCTKGEKGD	OTOL1	196	A6NHN0
GNCTKGEKGDQGAMG	OTOL1	201	A6NHN0
VELGGKVSVNCAKTG	OSBPL11	581	Q9BXB4
GCKVVGAVGSDEKVA	PTGR1	166	Q14914
KGKVDLKCVGEAAGG	MIB2	216	Q96AX9
KKGECAVGASGAQNG	MN1	1181	Q10571
KGTDGGRAEKVLEAC	SHMT1	366	P34896
KDGGVCLLSGTKGAS	IGF2R	1851	P11717
GGAGKTVKCVFLDED	SOX11	211	P35716
KIVIVGDGGCGKTSL	RHOF	21	Q9HBH0
CSFSGGVKQEKTEDG	TRIM33	786	Q9UPN9
GGKQVVVCGYGEVGK	AHCYL2	391	Q96HN2
GSQGERGKDKKGSCN	GFPT1	241	Q06210
GKQVVVCGYGEVGKG	AHCYL1	311	O43865
EGGGSEVFQELKGIC	FAM98A	136	Q8NCA5
RGEEIDTGGGKQESC	UPF3A	301	Q9H1J1
ALGGDNVTGVDCVKG	SLC9A3	236	P48764
SDSKGKNTCGGFLGE	ERCC5	1076	P28715
GEKVCALGGSKAHDG	WDR1	221	O75083
SGTEKDKGNCGVGKS	ARHGAP5	21	Q13017
SGECRKGVGAGEEKD	RUSC1-AS1	76	Q66K80
LSGTEKEKGQCGIGK	ARHGAP35	21	Q9NRY4
EDKPQGGACAGLKED	COA5	6	Q86WW8
KGICGKTRIAEVGGV	C11orf54	51	Q9H0W9
GACGLSEEKAVEKFG	TXNRD1	531	Q16881
GGEFGKEGEGRCEQV	nan	21	Q9BRP9
TKTGDGCEGGTDVKG	XAGE2	76	Q96GT9
GIKCVLVGDGAVGKS	RHOV	31	Q96L33
RVVGDGGSISKGKIC	TUBE1	51	Q9UJT0
GEASGFVKDGDKLCV	SNX18	246	Q96RF0
EELVKGLKEQCTGGC	TNXB	111	P22105
GGEESLKCEDLKVGQ	TM2D1	41	Q9BX74
KDGLNQAKKGGVSCG	WAPL	331	Q7Z5K2
KEQGKDSCQGDSGGR	PRSS42P	256	Q7Z5A4
LGDCSGVVGDGGVKL	ELAC1	251	Q9H777
GVVGDGGVKLCFEAD	ELAC1	256	Q9H777
KAGASKTGLCQAEGD	ZNF469	1671	Q96JG9
VGCKGSKAGIEQEGY	ZMYND11	71	Q15326
GLGSDDGVCTKITQK	ZNF543	156	Q08ER8
ACKLEGGDCGEGVQI	THSD7B	1311	Q9C0I4
KVVDKCGVCGGDNTG	THSD4	396	Q6ZMP0
KNAKEEQGDLKCGGV	ZMYM4	1221	Q5VZL5
GEGCEFQGKLDRKQG	ZKSCAN5	501	Q9Y2L8
GRDEGCKLVTIGSGK	GRIN2B	741	Q13224