Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3T6 kinase activity	PRKCA PRKCB	6.87e-05	2	166	2	GO:0035403
GeneOntologyMolecularFunction	histone kinase activity	DCAF1 PRKCA PRKCB PKN1	8.07e-05	28	166	4	GO:0035173
GeneOntologyMolecularFunction	histone H3 kinase activity	PRKCA PRKCB PKN1	1.17e-04	12	166	3	GO:0140996
GeneOntologyMolecularFunction	diacylglycerol-dependent serine/threonine kinase activity	PRKCA PRKCB PKN1	2.92e-04	16	166	3	GO:0004697
GeneOntologyBiologicalProcess	negative regulation of mitotic cell cycle	CEP192 BTN2A1 CTDSP2 KLHL22 MEIOC BRINP2 FOXO4 CTNNB1 RPA2 CTDSPL TP53	1.66e-05	282	164	11	GO:0045930
GeneOntologyBiologicalProcess	negative regulation of cell cycle	IPO5 CEP192 BTN2A1 CTDSP2 KLHL22 BMP2 MEIOC MOV10L1 BRINP2 FOXO4 CTNNB1 RPA2 CTDSPL TP53	2.14e-05	464	164	14	GO:0045786
Domain	ARM-type_fold	DCAF1 IPO5 DNAJC13 TNPO2 PSMD5 FRYL HEATR1 VIRMA INF2 AOPEP RIPOR1 CTNNB1 AGBL1	1.17e-05	339	167	13	IPR016024
Domain	WD40_repeat_dom	DCAF1 DCAF6 WDR36 TAF1C NEDD1 DCAF12L1 WDR6 WDR87 KCTD3 WDR90 BTRC NSMAF	1.53e-05	297	167	12	IPR017986
Domain	-	DCAF1 IPO5 DNAJC13 TNPO2 PSMD5 FRYL HEATR1 RIPOR1 CTNNB1 MED12	3.20e-05	222	167	10	1.25.10.10
Domain	ARM-like	DCAF1 IPO5 DNAJC13 TNPO2 PSMD5 FRYL HEATR1 RIPOR1 CTNNB1 AGBL1 MED12	3.24e-05	270	167	11	IPR011989
Domain	WD_REPEATS_1	DCAF1 DCAF6 WDR36 NEDD1 DCAF12L1 WDR6 WDR87 KCTD3 WDR90 BTRC NSMAF	4.23e-05	278	167	11	PS00678
Domain	WD_REPEATS_2	DCAF1 DCAF6 WDR36 NEDD1 DCAF12L1 WDR6 WDR87 KCTD3 WDR90 BTRC NSMAF	4.37e-05	279	167	11	PS50082
Domain	WD_REPEATS_REGION	DCAF1 DCAF6 WDR36 NEDD1 DCAF12L1 WDR6 WDR87 KCTD3 WDR90 BTRC NSMAF	4.37e-05	279	167	11	PS50294
Domain	-	DCAF1 DCAF6 WDR36 TAF1C NEDD1 DCAF12L1 WDR6 WDR87 KCTD3 WDR90 BTRC NSMAF	4.70e-05	333	167	12	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	DCAF1 DCAF6 WDR36 TAF1C NEDD1 DCAF12L1 WDR6 WDR87 KCTD3 WDR90 BTRC NSMAF	4.98e-05	335	167	12	IPR015943
Domain	Quinoprotein_ADH-like_supfam	WDR36 WDR6 WDR87 WDR90 EIF2AK3	1.09e-04	53	167	5	IPR011047
Domain	WD40	DCAF6 WDR36 NEDD1 DCAF12L1 WDR6 WDR87 KCTD3 WDR90 BTRC NSMAF	1.54e-04	268	167	10	SM00320
Domain	WD40_repeat	DCAF6 WDR36 NEDD1 DCAF12L1 WDR6 WDR87 KCTD3 WDR90 BTRC NSMAF	1.73e-04	272	167	10	IPR001680
Domain	Protein_kinase_C_a/b/g	PRKCA PRKCB	2.37e-04	3	167	2	IPR014375
Domain	Gal_mutarotase_N	GAA MGAM2	4.71e-04	4	167	2	IPR031727
Domain	Oxidoreductase_N	DHDH GFOD2	4.71e-04	4	167	2	IPR000683
Domain	GFO_IDH_MocA	DHDH GFOD2	4.71e-04	4	167	2	PF01408
Domain	NtCtMGAM_N	GAA MGAM2	4.71e-04	4	167	2	PF16863
Domain	WD40	DCAF6 WDR36 NEDD1 DCAF12L1 WDR6 WDR87 WDR90 BTRC NSMAF	5.51e-04	259	167	9	PF00400
Domain	BTB-kelch_protein	KLHL28 KLHL22 KLHL21 KLHL33	5.80e-04	43	167	4	IPR017096
Domain	Dullard_phosphatase	CTDSP2 CTDSPL	7.81e-04	5	167	2	IPR011948
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TBC1D19 DIP2B CACNB3 DCAF6 DNAJC13 NEDD4L ERV3-1 FRYL CEP192 NEDD1 TTC3 C2CD2 PTK7 SH3BP4 NCOR2 KIDINS220 INF2 KCND3 AOPEP USP40 ANKRD11 MACF1 RIPOR1 PKN1 LRRC7 OXSR1 CTDSPL NBR1 NSMAF	2.01e-10	1489	170	29	28611215
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DCAF1 NEDD4L SYNE1 CEP192 URB2 VIRMA ASAP1 KIDINS220 STARD9 BRINP2 MACF1 RIPOR1 LRRC7 SYVN1 SIPA1L2 SRRM2	2.01e-10	407	170	16	12693553
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1E DIP2B PDE4A DNAJC13 MAGED1 NEDD4L SYNE1 ETF1 GRIN1 TTC3 VIRMA PREPL NCOR2 SVIL STON2 PRKCA PRKCB MACF1 PKN1 LRRC7 CTNNB1	1.19e-08	963	170	21	28671696
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	DCAF1 DNAJC13 MAGED1 WDR36 SYNE1 CEP192 HEATR1 TTC3 PREPL PTK7 SH3BP4 LRRC47 ZC3H7A KIDINS220 INF2 WDR6 ANKRD11 MACF1 EEF2K CTNNB1 LAS1L C9orf72 SIPA1L2 SRRM2 EIF2AK3 NBR1	1.77e-08	1487	170	26	33957083
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	CACNA1E NEDD4L TNC CPEB3 GRIN1 SPECC1 PRKCA PRKCB MACF1 LRRC7 CTNNB1 SIPA1L2 SRRM2	1.89e-08	347	170	13	17114649
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CCDC71L PDE4A PCNX3 FRYL CEP192 TTC3 C2CD2 CTDSP2 SH3BP4 NCOR2 INF2 KLHL21 CCDC3 USP40 ANKRD11 RIPOR1 PKN1 WDR90 SYVN1 SIPA1L2 CPVL MED12	2.63e-08	1105	170	22	35748872
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	IPO5 DNAJC13 NEDD4L TNC SYNE1 ETF1 GRIN1 SPECC1 VIRMA JMY ASAP1 LRRC47 KIDINS220 INF2 KCND3 SVIL STON2 KMT2A PRKCA PRKCB MACF1 LRRC7 CTNNB1 SIPA1L2	1.43e-07	1431	170	24	37142655
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DIP2B NEDD4L FRYL CEP192 SPECC1 VIRMA SH3BP4 STARD9 SVIL ANKRD11 MIEF1 KMT2A MACF1 FOXO4 SIPA1L2 SRRM2 TP53 OTOG	2.62e-07	861	170	18	36931259
Pubmed	Nanomolar amyloid beta protein activates a specific PKC isoform mediating phosphorylation of MARCKS in Neuro2A cells.	PRKCA PRKCB PKN1	4.57e-07	4	170	3	11930178
Pubmed	BMP-2 modulates beta-catenin signaling through stimulation of Lrp5 expression and inhibition of beta-TrCP expression in osteoblasts.	BMP2 CTNNB1 BTRC	4.57e-07	4	170	3	19795382
Pubmed	PRK1 phosphorylates MARCKS at the PKC sites: serine 152, serine 156 and serine 163.	PRKCA PRKCB PKN1	4.57e-07	4	170	3	8557118
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DCAF1 DNAJC13 WDR36 WASHC4 TAF1C PSMD5 HEATR1 URB2 NCCRP1 ASAP1 LRRC47 ZC3H7A NCOR2 INF2 WDR6 HLTF PRKCA MACF1 LAS1L SRRM2 MED12 BTRC	8.36e-07	1353	170	22	29467282
Pubmed	Hypoxia-induced β-catenin downregulation involves p53-dependent activation of Siah-1.	CTNNB1 BTRC TP53	2.27e-06	6	170	3	21466614
Pubmed	Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4.	PRKCA PRKCB PKN1	2.27e-06	6	170	3	20228790
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	SYNE1 XIRP2 MCM9 MACF1	2.51e-06	20	170	4	21689717
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	IPO5 WDR36 FRYL HEATR1 URB2 VIRMA LRRC47 WDR6 KMT2A MACF1 LAS1L SRRM2 MED12 TP53	4.47e-06	653	170	14	22586326
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	MAGED1 NEDD1 KIDINS220 MEIOC SVIL MACF1 LRRC7 SIPA1L2 NBR1	6.45e-06	263	170	9	34702444
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	NEDD4L SPECC1 PTK7 KIDINS220 INF2 GFOD2 WDR6 MACF1 CTNNB1 SIPA1L2 CTDSPL	7.93e-06	421	170	11	36976175
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	IPO5 MAGED1 WDR36 TNPO2 GCDH HEATR1 XRCC1 SPECC1 PTGFRN JMY LRRC47 INF2 WDR6 HLTF KMT2A PRKCA CTNNB1 LAS1L RPA2 CPVL BTRC	8.14e-06	1440	170	21	30833792
Pubmed	Novel interactors and a role for supervillin in early cytokinesis.	PCNX3 STARD9 SVIL KMT2A	1.03e-05	28	170	4	20309963
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	CACNA1E CACNB3 SYNE1 GRIN1 ASAP1 PRKCA PRKCB MACF1 LRRC7	1.10e-05	281	170	9	28706196
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	DNAJC13 NEDD4L ETF1 FRYL XRCC1 SH3BP4 NCOR2 SVIL USP32 ANKRD11 CTNNB1 NBR1	1.44e-05	536	170	12	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	DNAJC13 NEDD4L ETF1 FRYL XRCC1 SH3BP4 NCOR2 SVIL USP32 ANKRD11 CTNNB1 NBR1	1.49e-05	538	170	12	10512203
Pubmed	Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.	DNAJC13 MAGED1 WDR36 PCNX3 HEATR1 XRCC1 TTC3 NCCRP1 KLHL22 KIDINS220 CTNNB1 ASPRV1 SIPA1L2 RPA2	1.61e-05	732	170	14	34732716
Pubmed	BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.	MAGED1 NEDD1 GADD45GIP1 LRRC47 EEF2K CTNNB1 CPVL BTRC	1.67e-05	226	170	8	25900982
Pubmed	Phosphorylation of tau is regulated by PKN.	PRKCA PRKCB PKN1	1.84e-05	11	170	3	11104762
Pubmed	Genome wide study of maternal and parent-of-origin effects on the etiology of orofacial clefts.	SH3BP4 LRRC7 FHIT	1.84e-05	11	170	3	22419666
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	IPO5 DCAF6 MAGED1 WASHC4 TNPO2 SYNE1 TAF1C PSMD5 TTC3 NR1D1 SPECC1 RFX5 LRP1B PREPL STAT6 USP32 MACF1 BTRC ECE2	1.87e-05	1285	170	19	35914814
Pubmed	Prognostic role of beta-catenin and p53 expression in the metastatic progression of sporadic colorectal cancer.	CTNNB1 TP53	2.38e-05	2	170	2	20129645
Pubmed	Heterogeneity of cellular proliferation within transitional cell carcinoma: correlation of protein kinase C alpha/betaI expression and activity.	PRKCA PRKCB	2.38e-05	2	170	2	16517978
Pubmed	Calcium-dependent isoforms of protein kinase C mediate posttetanic potentiation at the calyx of Held.	PRKCA PRKCB	2.38e-05	2	170	2	21658591
Pubmed	Combined expression of aldehyde dehydrogenase 1A1 and β-catenin is associated with lymph node metastasis and poor survival in breast cancer patients following cyclophosphamide treatment.	ALDH1A1 CTNNB1	2.38e-05	2	170	2	26398662
Pubmed	TP53 and DNA-repair gene polymorphisms genotyping as a low-cost lung adenocarcinoma screening tool.	XRCC1 TP53	2.38e-05	2	170	2	30467244
Pubmed	Prognostic significance of p53 and X-ray repair cross-complementing group 1 polymorphisms on prostate-specific antigen recurrence in prostate cancer post radical prostatectomy.	XRCC1 TP53	2.38e-05	2	170	2	18006764
Pubmed	Regulation of the p53 protein by protein kinase C alpha and protein kinase C zeta.	PRKCA TP53	2.38e-05	2	170	2	9571186
Pubmed	hNRAGE, a human neurotrophin receptor interacting MAGE homologue, regulates p53 transcriptional activity and inhibits cell proliferation.	MAGED1 TP53	2.38e-05	2	170	2	15094062
Pubmed	Transient activation of PKC results in long-lasting detrimental effects on systolic [Ca2+]i in cardiomyocytes by altering actin cytoskeletal dynamics and T-tubule integrity.	PRKCA PRKCB	2.38e-05	2	170	2	29307535
Pubmed	Genes encoding catalytic subunits of protein kinase A and risk of spina bifida.	PRKCA PRKCB	2.38e-05	2	170	2	16080189
Pubmed	Overexpression of human beta TrCP1 deleted of its F box induces tumorigenesis in transgenic mice.	CTNNB1 BTRC	2.38e-05	2	170	2	15735746
Pubmed	A transcription co-factor integrates cell adhesion and motility with the p53 response.	JMY TP53	2.38e-05	2	170	2	19897726
Pubmed	Transcriptome analysis reveals that p53 and {beta}-catenin alterations occur in a group of aggressive adrenocortical cancers.	CTNNB1 TP53	2.38e-05	2	170	2	20959480
Pubmed	Generation of a poor prognostic chronic lymphocytic leukemia-like disease model: PKCα subversion induces up-regulation of PKCβII expression in B lymphocytes.	PRKCA PRKCB	2.38e-05	2	170	2	25616575
Pubmed	Role of p53 and β-catenin mutations in conjunction with CK19 expression on early tumor recurrence and prognosis of hepatocellular carcinoma.	CTNNB1 TP53	2.38e-05	2	170	2	21061181
Pubmed	The globular heads of the C1q receptor regulate apoptosis in human cervical squamous carcinoma cells via a p53-dependent pathway.	CD93 TP53	2.38e-05	2	170	2	23268996
Pubmed	TMARg, a Novel Anthraquinone Isolated from Rubia cordifolia Nakai, Increases Osteogenesis and Mineralization through BMP2 and β-Catenin Signaling.	BMP2 CTNNB1	2.38e-05	2	170	2	32727092
Pubmed	ALDH1A1 maintains the cancer stem-like cells properties of esophageal squamous cell carcinoma by activating the AKT signal pathway and interacting with β-catenin.	ALDH1A1 CTNNB1	2.38e-05	2	170	2	32044720
Pubmed	A novel therapeutic approach with Caviunin-based isoflavonoid that en routes bone marrow cells to bone formation via BMP2/Wnt-β-catenin signaling.	BMP2 CTNNB1	2.38e-05	2	170	2	25232676
Pubmed	Mechanical unloading reduces microtubule actin crosslinking factor 1 expression to inhibit β-catenin signaling and osteoblast proliferation.	MACF1 CTNNB1	2.38e-05	2	170	2	29219183
Pubmed	Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease.	NOX1 PRKCA	2.38e-05	2	170	2	23349388
Pubmed	Beta-catenin and p53 expression in topographic compartments of colorectal cancer and its prognostic value following surgery.	CTNNB1 TP53	2.38e-05	2	170	2	29146051
Pubmed	Epithelial-mesenchymal transdifferentiation of renal tubular epithelial cells induced by urinary proteins requires the activation of PKC-α and βI isozymes.	PRKCA PRKCB	2.38e-05	2	170	2	21323641
Pubmed	Inactivation of both FHIT and p53 cooperate in deregulating proliferation-related pathways in lung cancer.	FHIT TP53	2.38e-05	2	170	2	22425911
Pubmed	NRAGE induces β-catenin/Arm O-GlcNAcylation and negatively regulates Wnt signaling.	MAGED1 CTNNB1	2.38e-05	2	170	2	28427939
Pubmed	Protein kinase C alpha, betaI, and betaII isozymes regulate cytokine production in mast cells through MEKK2/ERK5-dependent and -independent pathways.	PRKCA PRKCB	2.38e-05	2	170	2	16430878
Pubmed	Suppression of PKC causes oncogenic stress for triggering apoptosis in cancer cells.	PRKCA PRKCB	2.38e-05	2	170	2	28415683
Pubmed	cPKC-dependent sequestration of membrane-recycling components in a subset of recycling endosomes.	PRKCA PRKCB	2.38e-05	2	170	2	14527960
Pubmed	ALDH1A1 regulates postsynaptic μ-opioid receptor expression in dorsal striatal projection neurons and mitigates dyskinesia through transsynaptic retinoic acid signaling.	PITX3 ALDH1A1	2.38e-05	2	170	2	30837649
Pubmed	Interaction between TP53 and XRCC1 increases susceptibility to cervical cancer development: a case control study.	XRCC1 TP53	2.38e-05	2	170	2	30616520
Pubmed	The XRCC1 and TP53 gene polymorphisms are associated with advanced-stage disease and early distant metastasis at diagnosis in non-small cell lung cancer.	XRCC1 TP53	2.38e-05	2	170	2	37787291
Pubmed	Effects of azidothymidine on protein kinase C activity and expression in erythroleukemic cell K562 and acute lymphoblastic leukemia cell HSB-2.	PRKCA PRKCB	2.38e-05	2	170	2	25693686
Pubmed	ALDH1A1 and HLTF modulate the activity of lysosomal autophagy inhibitors in cancer cells.	HLTF ALDH1A1	2.38e-05	2	170	2	28981387
Pubmed	DCAF1 controls T-cell function via p53-dependent and -independent mechanisms.	DCAF1 TP53	2.38e-05	2	170	2	26728942
Pubmed	Beta-catenin signaling pathway is crucial for bone morphogenetic protein 2 to induce new bone formation.	BMP2 CTNNB1	2.38e-05	2	170	2	17085452
Pubmed	Deletion of densin-180 results in abnormal behaviors associated with mental illness and reduces mGluR5 and DISC1 in the postsynaptic density fraction.	GRIN1 LRRC7	2.38e-05	2	170	2	22072671
Pubmed	Reactivation of fetal splicing programs in diabetic hearts is mediated by protein kinase C signaling.	PRKCA PRKCB	2.38e-05	2	170	2	24151077
Pubmed	All-trans retinoic acid and protein kinase C α/β1 inhibitor combined treatment targets cancer stem cells and impairs breast tumor progression.	PRKCA PRKCB	2.38e-05	2	170	2	33723318
Pubmed	AChE deficiency or inhibition decreases apoptosis and p53 expression and protects renal function after ischemia/reperfusion.	ACHE TP53	2.38e-05	2	170	2	20054652
Pubmed	PTK7: a cell polarity receptor with multiple facets.	PTK7 CTNNB1	2.38e-05	2	170	2	21415598
Pubmed	Requirement for the Xrcc1 DNA base excision repair gene during early mouse development.	XRCC1 TP53	2.38e-05	2	170	2	10191063
Pubmed	Biophysical investigation of the dual binding surfaces of human transcription factors FOXO4 and p53.	FOXO4 TP53	2.38e-05	2	170	2	34954873
Pubmed	Molecular genetic alterations of FHIT and p53 genes in benign and malignant thyroid gland lesions.	FHIT TP53	2.38e-05	2	170	2	16698048
Pubmed	Antitumor activity of potent pyruvate dehydrogenase kinase 4 inhibitors from plants in pancreatic cancer.	PDK4 ALDH1A1	2.38e-05	2	170	2	31106493
Pubmed	Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo.	CTNNB1 TP53	2.38e-05	2	170	2	18160717
Pubmed	Inhibiting β-catenin disables nucleolar functions in triple-negative breast cancer.	CTNNB1 LAS1L	2.38e-05	2	170	2	33664239
Pubmed	Distinct and complementary roles for α and β isoenzymes of PKC in mediating vasoconstrictor responses to acutely elevated glucose.	PRKCA PRKCB	2.38e-05	2	170	2	26660275
Pubmed	Insulin inhibits phagocytosis in normal human neutrophils via PKCalpha/beta-dependent priming of F-actin assembly.	PRKCA PRKCB	2.38e-05	2	170	2	16673150
Pubmed	Association between XRCC1 ARG399GLN and P53 ARG72PRO polymorphisms and the risk of gastric and colorectal cancer in Turkish population.	XRCC1 TP53	2.38e-05	2	170	2	21971103
Pubmed	Translocation (4;11)(p12;q23) with rearrangement of FRYL and MLL in therapy-related acute myeloid leukemia.	FRYL KMT2A	2.38e-05	2	170	2	17854671
Pubmed	MLL gene amplification in acute myeloid leukemia and myelodysplastic syndromes is associated with characteristic clinicopathological findings and TP53 gene mutation.	KMT2A TP53	2.38e-05	2	170	2	25387813
Pubmed	Sporadic childhood hepatoblastomas show activation of beta-catenin, mismatch repair defects and p53 mutations.	CTNNB1 TP53	2.38e-05	2	170	2	17962810
Pubmed	Receptor-specific regulation of atrial GIRK channel activity by different Ca2+-dependent PKC isoforms.	PRKCA PRKCB	2.38e-05	2	170	2	31525436
Pubmed	Alterations of FHIT and P53 genes in keratocystic odontogenic tumor, dentigerous and radicular cyst.	FHIT TP53	2.38e-05	2	170	2	18221322
Pubmed	STD and TRNOESY NMR studies on the conformation of the oncogenic protein beta-catenin containing the phosphorylated motif DpSGXXpS bound to the beta-TrCP protein.	CTNNB1 BTRC	2.38e-05	2	170	2	15927956
Pubmed	A protein knockdown strategy to study the function of beta-catenin in tumorigenesis.	CTNNB1 BTRC	2.38e-05	2	170	2	14516475
Pubmed	Unravelling the different functions of protein kinase C isoforms in platelets.	PRKCA PRKCB	2.38e-05	2	170	2	21596041
Pubmed	ALCAP2 inhibits lung adenocarcinoma cell proliferation, migration and invasion via the ubiquitination of β-catenin by upregulating the E3 ligase NEDD4L.	NEDD4L CTNNB1	2.38e-05	2	170	2	34330894
Pubmed	Identification of ANKRD11 as a p53 coactivator.	ANKRD11 TP53	2.38e-05	2	170	2	18840648
Pubmed	Polymorphism of XRCC1 and the frequency of mutation in codon 249 of the p53 gene in hepatocellular carcinoma among Guangxi population, China.	XRCC1 TP53	2.38e-05	2	170	2	17849423
Pubmed	Evaluation of CTNNB1 and TP53 variability in patients with hepatocellular carcinoma and occult hepatitis B virus infection.	CTNNB1 TP53	2.38e-05	2	170	2	26341700
Pubmed	Reduced membranous beta-catenin protein expression is associated with metastasis and poor prognosis in squamous cell carcinoma of the esophagus.	CTNNB1 TP53	2.38e-05	2	170	2	18455580
Pubmed	AF4p12, a human homologue to the furry gene of Drosophila, as a novel MLL fusion partner.	FRYL KMT2A	2.38e-05	2	170	2	16061630
Pubmed	The essentiality of PKCalpha and PKCbetaI translocation for CD14+monocyte differentiation towards macrophages and dendritic cells, respectively.	PRKCA PRKCB	2.38e-05	2	170	2	17455194
Pubmed	Calcium-dependent isoforms of protein kinase C mediate glycine-induced synaptic enhancement at the calyx of Held.	PRKCA PRKCB	2.38e-05	2	170	2	23035091
Pubmed	Distinct functions of protein kinase Calpha and protein kinase Cbeta during retinoic acid-induced differentiation of F9 cells.	PRKCA PRKCB	2.38e-05	2	170	2	9486851
Pubmed	The Relationship between Gene Polymorphisms od the XRCC1 and TP53 with the Gender of Children with Acute Leukemia.	XRCC1 TP53	2.38e-05	2	170	2	36853312
Pubmed	Deficiency of retinaldehyde dehydrogenase 1 induces BMP2 and increases bone mass in vivo.	BMP2 ALDH1A1	2.38e-05	2	170	2	23951127
Pubmed	Glucose deprivation triggers protein kinase C-dependent β-catenin proteasomal degradation.	PRKCA CTNNB1	2.38e-05	2	170	2	25691573
Pubmed	Hepatitis B virus-associated hepatocellular carcinoma from India: role of viral genotype and mutations in CTNNB1 (beta-catenin) and TP53 genes.	CTNNB1 TP53	2.38e-05	2	170	2	20963515
Pubmed	Depressive-Like Behaviors Are Regulated by NOX1/NADPH Oxidase by Redox Modification of NMDA Receptor 1.	GRIN1 NOX1	2.38e-05	2	170	2	28314819
Pubmed	Impaired p53 binding to importin: a novel mechanism of cytoplasmic sequestration identified in oxaliplatin-resistant cells.	IPO5 TP53	2.38e-05	2	170	2	19581934
Interaction	RNF128 interactions	DNAJC13 NEDD4L STAT6 PTK7 WDR6 CTNNB1 BTRC TP53	8.09e-08	67	167	8	int:RNF128
Interaction	CHUK interactions	MAGED1 TTC3 NCOR2 KLHL21 USP32 PRKCA PRKCB CTNNB1 RPA2 NBR1 BTRC TP53	3.82e-07	224	167	12	int:CHUK
Interaction	VASP interactions	DIP2B MAGED1 CEP192 VIRMA JMY XIRP2 INF2 SVIL CTNNB1 SIPA1L2 NBR1 TP53 NSMAF	1.10e-06	294	167	13	int:VASP
Interaction	SFN interactions	IPO5 NEDD4L FRYL CEP192 GCKR SPECC1 VIRMA SH3BP4 SVIL MIEF1 KMT2A MACF1 FOXO4 OXSR1 CTNNB1 C9orf72 SIPA1L2 SRRM2 RPA2 TP53	1.25e-06	692	167	20	int:SFN
Interaction	USP29 interactions	VIRMA CTDSP2 CTNNB1 CTDSPL TP53	1.38e-06	24	167	5	int:USP29
Interaction	ABCF2 interactions	WDR36 ETF1 VIRMA WDR6 SVIL PRKCB LRRC7 CTNNB1 C9orf72 RPA2 TP53	1.41e-06	209	167	11	int:ABCF2
Interaction	CCT5 interactions	DCAF6 DNAJC13 PDK4 TAF1C NEDD1 VIRMA ZC3H7A FGR KLHL33 C9orf72 SRRM2 RPA2 NBR1 MED12 BTRC TP53 NSMAF	1.82e-06	525	167	17	int:CCT5
Interaction	NFE2L2 interactions	DCAF1 GADD45GIP1 NCOR2 PRKCA ELF5 SYVN1 EIF2AK3 BTRC TP53	7.30e-06	159	167	9	int:NFE2L2
Interaction	TOP3B interactions	IPO5 CCDC71L PDE4A WDR36 PCNX3 FRYL CEP192 NEDD1 TTC3 C2CD2 CTDSP2 SH3BP4 ZC3H7A NCOR2 INF2 KLHL21 SVIL CCDC3 USP40 ANKRD11 RIPOR1 PKN1 WDR90 SYVN1 SIPA1L2 RPA2 CPVL MED12 TP53	1.06e-05	1470	167	29	int:TOP3B
Interaction	TNIK interactions	CACNA1E NEDD4L SYNE1 GRIN1 VIRMA NCOR2 PRKCB MACF1 LRRC7 CTNNB1 RPA2 CPVL TP53	1.82e-05	381	167	13	int:TNIK
Interaction	SLC12A1 interactions	NEDD4L USP40 OXSR1	3.04e-05	8	167	3	int:SLC12A1
Interaction	YWHAB interactions	IPO5 NEDD4L FRYL CEP192 GCKR SPECC1 VIRMA SH3BP4 STARD9 SVIL USP32 MIEF1 KMT2A MACF1 FOXO4 C9orf72 SIPA1L2 SRRM2 RPA2 BTRC TP53 OTOG	3.45e-05	1014	167	22	int:YWHAB
Interaction	CCT2 interactions	PDK4 TAF1C NEDD1 VIRMA ZC3H7A MACF1 ELF5 WDR90 CTNNB1 FGR KLHL33 C9orf72 RPA2 NBR1 BTRC TP53 NSMAF	4.02e-05	666	167	17	int:CCT2
Interaction	VCL interactions	CEP192 VIRMA ASAP1 KIDINS220 SVIL PRKCA MACF1 CTNNB1 C9orf72 SIPA1L2 RPA2	4.96e-05	305	167	11	int:VCL
Interaction	KLHL13 interactions	KLHL28 VIRMA KLHL22 KLHL21 C9orf72 RPA2	6.16e-05	82	167	6	int:KLHL13
Interaction	BAG2 interactions	DNAJC13 WASHC4 NEDD1 VIRMA PTK7 KCTD3 PRKCB OXSR1 FGR C9orf72 SRRM2 RPA2 MED12 BTRC TP53 NLRP5	6.25e-05	622	167	16	int:BAG2
Interaction	AGAP2 interactions	CACNA1E CACNB3 SYNE1 GRIN1 ASAP1 PRKCA PRKCB MACF1 LRRC7	6.60e-05	210	167	9	int:AGAP2
Interaction	WASHC2A interactions	DNAJC13 WASHC4 VIRMA SRRM2 RPA2 BTRC TP53	7.13e-05	122	167	7	int:WASHC2A
Interaction	GPS1 interactions	DCAF1 DCAF6 TNPO2 SYNE1 VIRMA FBXO10 WDR6 RPA2 TP53	8.79e-05	218	167	9	int:GPS1
Interaction	TUBA4A interactions	MAGED1 VIRMA C2CD2 JMY DHDH AOPEP AVIL BRINP2 PRKCB KLHL33 C9orf72 SRRM2 RPA2 TP53	9.66e-05	512	167	14	int:TUBA4A
Interaction	CCT4 interactions	DNAJC13 PDK4 NEDD1 VIRMA MACF1 CTNNB1 FGR KLHL33 C9orf72 RPA2 NBR1 BTRC TP53 NSMAF	1.03e-04	515	167	14	int:CCT4
Interaction	LYN interactions	IPO5 PDE4A SPECC1 VIRMA PTK7 SH3BP4 KIDINS220 WDR6 SVIL KMT2A PRKCB MACF1 CTNNB1 FGR SRRM2 RPA2 TP53	1.05e-04	720	167	17	int:LYN
Interaction	CNOT2 interactions	PDK4 CEP192 ZC3H7A NCOR2 CTNNB1 RPA2 CPVL BTRC	1.22e-04	178	167	8	int:CNOT2
Interaction	MYO1C interactions	SPECC1 VIRMA JMY INF2 SVIL PRKCA CTNNB1 SYVN1 C9orf72 RPA2 MED12 TP53	1.22e-04	397	167	12	int:MYO1C
GeneFamily	C2 domain containing protein kinases	PRKCA PRKCB PKN1	2.76e-05	10	113	3	835
GeneFamily	WD repeat domain containing	DCAF6 WDR36 NEDD1 DCAF12L1 WDR6 WDR87 WDR90 BTRC NSMAF	3.95e-05	262	113	9	362
GeneFamily	Kelch like\|BTB domain containing	KLHL28 KLHL22 KLHL21 KLHL33	1.35e-04	42	113	4	617
GeneFamily	CTD family phosphatases	CTDSP2 CTDSPL	1.06e-03	8	113	2	1041
GeneFamily	Gelsolin/villins	AVIL SVIL	1.06e-03	8	113	2	950
Coexpression	EIF4E_DN	DIP2B NEDD4L PDK4 C2CD2 KLHL21 SVIL ANGPTL4	4.11e-06	100	170	7	M2790
Coexpression	NAKAYA_MYELOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	DCAF1 DNAJC13 WASHC4 PSMD5 GCDH ST6GAL1 CEP192 TTC3 SH3BP4 LRRC47 PRKCA MACF1	7.21e-06	378	170	12	M41174
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGED1 FRYL TTC3 FAM151A ANKRD11 KMT2A PRKCA PRKCB MACF1 SRRM2	4.32e-09	195	170	10	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGED1 FRYL TTC3 FAM151A ANKRD11 KMT2A PRKCA PRKCB MACF1 SRRM2	4.32e-09	195	170	10	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	CD8+_Memory_T_cell-RSV-6\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	CCDC71L PCNX3 TAF1C NR1D1 SPECC1 C2CD2 DHDH C1QTNF12	1.75e-07	158	170	8	5ae737757a49fc96bde1e57e02066f9f65654ea1
ToppCell	RSV-Healthy-6\|Healthy / Virus stimulation, Condition and Cluster	CCDC71L PCNX3 TAF1C NR1D1 SPECC1 C2CD2 DHDH C1QTNF12	2.33e-07	164	170	8	1b9c5a6dc4e09b90f92e98b81a5ee620f8479cc7
ToppCell	RSV-Healthy-6\|RSV / Virus stimulation, Condition and Cluster	CCDC71L PCNX3 TAF1C NR1D1 SPECC1 C2CD2 DHDH C1QTNF12	2.33e-07	164	170	8	ab312b8c2f828ea7331f2a340c4df81587a23b5c
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	SYNE1 CPEB3 LRP1B JMY KMT2A PRKCA FOXO4 NBR1	4.17e-07	177	170	8	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CACNA1E NCCRP1 XIRP2 KCND3 PITX3 KANK4 PRKCA	3.56e-06	166	170	7	6a6ed5c7a43fee9a8a9be42dfa99303815b8e8ef
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DCAF6 ACHE CPEB3 SLFN14 NOX1 BRINP2 FOXO4	3.85e-06	168	170	7	17fb9426eeea407b26fb895b8397faca95b7552d
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DCAF6 ACHE CPEB3 SLFN14 NOX1 BRINP2 FOXO4	3.85e-06	168	170	7	a61b39884851384cffd430079040546d125b2b40
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-4\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	CALHM5 MYCT1 CTDSP2 CD93 LOXHD1 HPGDS AVIL	5.04e-06	175	170	7	16849ea8f0985108baa2085f34c3de14a4f9f28b
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB3 CPEB3 SPECC1 AKR1E2 DHDH HPGDS WDR6	5.84e-06	179	170	7	2c3abd646d2c8992e8ff76a824eab5beba8ba4c6
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB3 CPEB3 SPECC1 AKR1E2 DHDH HPGDS WDR6	5.84e-06	179	170	7	6eb84fe9691ad40127b2d1f1c672428333c8fab4
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TNPO2 GCDH GFOD2 AOPEP KLHL21 RIPOR1 EIF2AK3	6.06e-06	180	170	7	62511d76d24b836839c3dcc2bf30485ffe9401e2
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_A2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	TNPO2 GCDH GFOD2 AOPEP KLHL21 RIPOR1 EIF2AK3	6.51e-06	182	170	7	03992d0ae519795239e4f2cc8e63f33c4482de6a
ToppCell	COVID_vent-Myeloid-Monocytic-SC_&_Eosinophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	MYCT1 PTK7 SH3BP4 HPGDS STON2 ALDH1A1 CTDSPL	8.33e-06	189	170	7	2157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC NR1D1 PTK7 AOPEP PRKCA ALDH1A1 SOD3	8.33e-06	189	170	7	32e6d6285b258831b965281224ff2aaeecdcb5f5
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC NR1D1 PTK7 AOPEP PRKCA ALDH1A1 SOD3	8.33e-06	189	170	7	385ef7bbd76c8047aeecf6542377d4213b5da5db
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NR1D1 PTK7 AOPEP ANGPTL4 MACF1 ALDH1A1 SOD3	8.93e-06	191	170	7	509230f50568e5a8ecf08edc4d58f9e2aa96efe9
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CALHM5 PTK7 IGSF10 GPR153 ANGPTL4 ALDH1A1 SOD3	8.93e-06	191	170	7	cd497abed9e00e4e0becd9dbc036c6e7a60ae791
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NR1D1 PTK7 AOPEP ANGPTL4 MACF1 ALDH1A1 SOD3	8.93e-06	191	170	7	0b3dbbc35d9970d3c749aef16dda59886b960e3d
ToppCell	facs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IPO5 TTC3 CD93 WDR6 RIPOR1 EEF2K GAA	9.23e-06	192	170	7	03dcd9405d3d76fc7455066ba5d83c09cd17072d
ToppCell	droplet-Lung-30m-Mesenchymal\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CALHM5 PTK7 IGSF10 GPR153 ANGPTL4 ALDH1A1 SOD3	9.23e-06	192	170	7	5d5bec238b196f0b3e727fd94f078d6ae524cb01
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB3 MAGED1 PDK4 NR1D1 PTGFRN PTK7 ALDH1A1	9.23e-06	192	170	7	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	DIP2B AOPEP SVIL ANKRD11 PRKCA MACF1 FHIT	9.23e-06	192	170	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGED1 NR1D1 IGSF10 ANGPTL4 ALDH1A1 GAA SOD3	9.55e-06	193	170	7	f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGED1 NR1D1 IGSF10 ANGPTL4 ALDH1A1 GAA SOD3	9.55e-06	193	170	7	85faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCell	facs-MAT-Fat-3m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGED1 NR1D1 IGSF10 ANGPTL4 ALDH1A1 GAA SOD3	9.55e-06	193	170	7	110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CALHM5 MEIOB PKDREJ PTK7 IGSF10 GPR153 SOD3	9.88e-06	194	170	7	7826fe5eb254ac032de0d978f39585a40e0b3ee4
ToppCell	Striatum-Macroglia-ASTROCYTE-Gja1-Sparc-Astrocyte.Gja1.Sparc-Car2_(Car2)-\|Striatum / BrainAtlas - Mouse McCarroll V32	ERV3-1 TNC AVIL ACSBG2 ELF5	1.01e-05	75	170	5	162b69b9934da4623ee378b0e8206c4e4917351b
ToppCell	Striatum-Macroglia-ASTROCYTE-Gja1-Sparc-Astrocyte.Gja1.Sparc-Car2_(Car2)\|Striatum / BrainAtlas - Mouse McCarroll V32	ERV3-1 TNC AVIL ACSBG2 ELF5	1.01e-05	75	170	5	98807389b7735b90024ba5e71be60cf95416c077
ToppCell	Striatum-Macroglia-ASTROCYTE-Gja1-Sparc\|Striatum / BrainAtlas - Mouse McCarroll V32	ERV3-1 TNC AVIL ACSBG2 ELF5	1.01e-05	75	170	5	15505f3e7a25b3ae51f0917335e92d6279e6d06d
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIN1 DCAF12L1 FAM151A PRKCA PRKCB CTDSPL GAA	1.02e-05	195	170	7	bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC71L PDE4A ETF1 JMY CD93 CPVL EIF2AK3	1.06e-05	196	170	7	01cea0bb0b938d0986fd2ddae06597b8af1768ee
ToppCell	Healthy/Control-Classical_Monocyte\|World / Disease group and Cell class	PDK4 CD93 ALDH1A1 FGR C9orf72 CPVL GAA	1.17e-05	199	170	7	527c767a09f911e319f7ad230b6518cebc0f367d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDK4 ST6GAL1 LRP1B ANGPTL4 ELF5 EIF2AK3	1.93e-05	144	170	6	5665dd2839b6c8ddbf5ddb2d22e1ee6073f74c3b
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	DCAF1 DCAF6 WDR6 TEDDM1 USP40 FOXO4	4.29e-05	166	170	6	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGED1 TTC3 FAM151A PRKCA PRKCB SRRM2	4.29e-05	166	170	6	66026988509e39e41274fa0de738383219e8ff30
ToppCell	COVID-19_Convalescent-Hematopoietic_SC\|COVID-19_Convalescent / Disease group, lineage and cell class	MYCT1 PTK7 IGSF10 XIRP2 HPGDS ALDH1A1	4.90e-05	170	170	6	8a73d5334eed1cd9fdcc3ebeae0bdf9f945c228a
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC-HSPC\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYCT1 PTK7 IGSF10 XIRP2 HPGDS ALDH1A1	5.06e-05	171	170	6	2031797d579ce373921affad70da6e50eec13664
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-mature_conventional_dendritic_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ACHE GRIN1 NCCRP1 SH3BP4 SLC6A12 PITX3	5.06e-05	171	170	6	d934d68efc5739483c735dc702ccd30b07a6aa7e
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC-HSPC-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYCT1 PTK7 IGSF10 XIRP2 HPGDS ALDH1A1	5.06e-05	171	170	6	a4e13b304ef414722ffdc06560deeab41785e956
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYCT1 PTK7 IGSF10 XIRP2 HPGDS ALDH1A1	5.06e-05	171	170	6	172db31a37b72fb87fe5f0f79da51866b90dd1ad
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC-HSPC-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MYCT1 PTK7 IGSF10 XIRP2 HPGDS ALDH1A1	5.23e-05	172	170	6	8fd3db757d54949bd583d5f0eadf63a32342cb9d
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	MYCT1 PTK7 IGSF10 XIRP2 HPGDS ALDH1A1	5.23e-05	172	170	6	da78f7a71b7f05c5c484c9ed19ba37c55d35e870
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MYCT1 NR1D1 NOX1 INF2 STARD9 USP32	5.23e-05	172	170	6	3b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC-HSPC\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	MYCT1 PTK7 IGSF10 XIRP2 HPGDS ALDH1A1	5.23e-05	172	170	6	382cb5fea099110eb026a8bba6cf4c28763ea52f
ToppCell	normal-na-Hematopoietic-Progen-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	MYCT1 SLFN14 LOXHD1 NOX1 HPGDS FHIT	5.40e-05	173	170	6	e666364eb110c1c976e5b09a632dd1454513f131
ToppCell	facs-Brain_Myeloid-Cerebellum-24m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UPK1A ERV3-1 MYCT1 ALDH1A1 C1QTNF12 AGBL1	5.40e-05	173	170	6	ef862e1d626bbc33191b433f483addff7f75ba16
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL28 NEDD4L PCNX3 SLC5A6 KANK4 BTRC	5.57e-05	174	170	6	c58328c2f262506a4518f49f148e29874faf9171
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CALHM5 SYT16 FAM151A AVIL FOXO4 ALDH1A1	5.57e-05	174	170	6	4da79da7a09ee1e345102c5331675ebcdbe56171
ToppCell	(9)_Platelet\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CALHM5 MYCT1 SLFN14 XIRP2 STON2 CTDSPL	6.13e-05	177	170	6	0830944c43de300815831a9e2b2fce40965e7d12
ToppCell	(9)_Platelet\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CALHM5 MYCT1 SLFN14 XIRP2 STON2 CTDSPL	6.13e-05	177	170	6	e63d01c7fce4fa1256212fa7e95f74281edb3a01
ToppCell	metastatic_Brain-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	PDK4 PSMD5 ST6GAL1 NCCRP1 ASAP1 GFOD2	6.32e-05	178	170	6	9a3581a0158dfa5a1cc942f8c532afb5e38b272a
ToppCell	PBMC-Convalescent-Hematopoietic-Platelet\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CALHM5 MYCT1 SLFN14 XIRP2 STON2 CTDSPL	6.32e-05	178	170	6	f5d83ad082e31d5601890d245b9fb4f9ef6a062b
ToppCell	PBMC-Convalescent-Hematopoietic-Platelet-Platelet\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CALHM5 MYCT1 SLFN14 XIRP2 STON2 CTDSPL	6.32e-05	178	170	6	a2a8fc14f492a4695e6991a357b6626145f1bf7f
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Dendritic_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CALHM5 PRKCA ALDH1A1 C1QTNF12 CTDSPL SOD3	6.72e-05	180	170	6	5b7d2336ed09d07f6b8dd91c1fa9c5ade633c104
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CEP192 RFX5 GPR153 RIPOR1 EEF2K FGR	6.72e-05	180	170	6	310a311c3ed924c912a800cf287a825de44b8775
ToppCell	facs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CALHM5 PRKCA ALDH1A1 C1QTNF12 CTDSPL SOD3	6.72e-05	180	170	6	d33bb00f2b7d07dda9015cb8eafd742c2b2e9ace
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYCT1 OIP5 SLFN14 HPGDS STON2 CTDSPL	6.93e-05	181	170	6	9dc0563453e24c9d1d975e2e0e1e272487e19908
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYCT1 OIP5 SLFN14 HPGDS STON2 CTDSPL	6.93e-05	181	170	6	14c2dd946e89ba578711c2d25935b6b3d319b701
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYCT1 OIP5 SLFN14 HPGDS STON2 CTDSPL	6.93e-05	181	170	6	c5843b89f3d362e236ff76c3279518a2fdfc1f75
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYCT1 OIP5 SLFN14 HPGDS STON2 CTDSPL	6.93e-05	181	170	6	fcefb5902416c004631f4f8dd5c8f99fe3bd90bc
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	NOX1 INF2 PRKCA SIPA1L2 PADI1 MGAM2	7.37e-05	183	170	6	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC ACHE KCND3 BRINP2 KANK4 ARHGAP28	7.37e-05	183	170	6	f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1B LOXHD1 XIRP2 GUCY2F ADAMTS20 OTOG	7.59e-05	184	170	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP\|bone_marrow / Manually curated celltypes from each tissue	MYCT1 IGSF10 HPGDS STON2 ALDH1A1 CTDSPL	7.59e-05	184	170	6	b81a2a95944cee8fec13d63dc0d95496e67aa937
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1B LOXHD1 XIRP2 GUCY2F ADAMTS20 OTOG	7.59e-05	184	170	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1B LOXHD1 XIRP2 GUCY2F ADAMTS20 OTOG	7.59e-05	184	170	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDE4A JMY CD93 PRKCB C9orf72 CPVL	7.59e-05	184	170	6	b45b1fdba13c8ed2a04a4fb3b62d8ad92785c768
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC PTGFRN IGSF10 CCDC3 ARHGAP28 SOD3	7.82e-05	185	170	6	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	MS-matDC\|MS / Condition, Cell_class and T cell subcluster	COL20A1 ACHE GRIN1 NCCRP1 TEX26 SOD3	7.82e-05	185	170	6	46bd897349598d85e718e25f9a045d2247723c61
ToppCell	MS-matDC-\|MS / Condition, Cell_class and T cell subcluster	COL20A1 ACHE GRIN1 NCCRP1 TEX26 SOD3	7.82e-05	185	170	6	9fbe70d3a7b106fb31e13b7f95029785f28ca6f4
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	WDR36 FRYL HEATR1 KIDINS220 MCM9 MACF1	7.82e-05	185	170	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC PTGFRN IGSF10 CCDC3 ARHGAP28 SOD3	7.82e-05	185	170	6	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC PTGFRN IGSF10 CCDC3 ARHGAP28 SOD3	7.82e-05	185	170	6	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	(8)_CD34_progenitor\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	MYCT1 IGSF10 HPGDS STON2 ALDH1A1 CTDSPL	8.06e-05	186	170	6	943c604a7cd873faf510096d094100512ba2d6bc
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	WDR36 FRYL HEATR1 KIDINS220 MCM9 MACF1	8.06e-05	186	170	6	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	(8)_CD34_progenitor\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	MYCT1 IGSF10 HPGDS STON2 ALDH1A1 CTDSPL	8.06e-05	186	170	6	e69a986b8618effd61875fda528a2e44aab11868
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYCT1 TAF1C SPECC1 CD93 CCDC3 EEF2K	8.54e-05	188	170	6	a37edd8f9e4a4e336b5acbb0407d3d275975cee8
ToppCell	facs-MAT-Fat-3m\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDK4 NR1D1 IGSF10 ANGPTL4 ALDH1A1 CTNNB1	8.54e-05	188	170	6	7da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SPECC1 CD93 HPGDS ALDH1A1 FGR CPVL	8.80e-05	189	170	6	2aebea7a6c2f83112d7c504b742f2c04b92e459a
ToppCell	droplet-Lung-immune-endo-depleted\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR1D1 PTK7 IGSF10 ANGPTL4 ALDH1A1 SOD3	8.80e-05	189	170	6	c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCell	droplet-Lung-immune-endo-depleted-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR1D1 PTK7 IGSF10 ANGPTL4 ALDH1A1 SOD3	8.80e-05	189	170	6	2a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-hematopoietic_progenitor-common_myeloid_progenitor\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MYCT1 IGSF10 HPGDS STON2 HLTF ALDH1A1	8.80e-05	189	170	6	56156325cc36b1329bf483f81bb74f371ef15e20
ToppCell	droplet-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NR1D1 PTK7 IGSF10 ANGPTL4 ALDH1A1 SOD3	8.80e-05	189	170	6	5a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TNC SPECC1 SVIL CCDC3 ARHGAP28 LRRC7	9.06e-05	190	170	6	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR1D1 PTK7 IGSF10 ANGPTL4 ALDH1A1 SOD3	9.06e-05	190	170	6	9cd147a174017ebda23cc47b6d4552d898acd092
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TNC SPECC1 SVIL CCDC3 ARHGAP28 LRRC7	9.06e-05	190	170	6	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	facs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC NR1D1 IGSF10 CCDC3 FAM131B SOD3	9.06e-05	190	170	6	c7bd087f36321cec61b98657433b4d19d135791f
ToppCell	facs-Marrow-KLS-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCT1 TTC3 RIPOR1 EEF2K ALDH1A1 GAA	9.06e-05	190	170	6	11f32f46661e44770782b8ec13c00028e1dfc3cd
ToppCell	facs-Lung-nan-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC NR1D1 IGSF10 CCDC3 FAM131B SOD3	9.06e-05	190	170	6	834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCell	facs-Marrow-KLS-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCT1 TTC3 RIPOR1 EEF2K ALDH1A1 GAA	9.06e-05	190	170	6	20f4f6fe09345878484086047061d6f900f9d476
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR1D1 PTK7 AOPEP ANGPTL4 ALDH1A1 SOD3	9.32e-05	191	170	6	a261f0738d974784bbdd60f23092bfbcca464459
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CALHM5 PTK7 GPR153 ANGPTL4 ALDH1A1 SOD3	9.32e-05	191	170	6	8a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR1D1 PTK7 AOPEP ANGPTL4 ALDH1A1 SOD3	9.32e-05	191	170	6	6594398cc8151c73696391a43ac110c10283dab1
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	WDR36 FRYL HEATR1 KIDINS220 MCM9 MACF1	9.32e-05	191	170	6	9454f642c3621370fa23640b631301346b300950
ToppCell	droplet-Lung-21m-Mesenchymal\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CALHM5 PTK7 GPR153 ANGPTL4 ALDH1A1 SOD3	9.32e-05	191	170	6	10a9db1caa0fdb51ace8537f42b2c66f7c97e0f5
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTK7 ANGPTL4 PRKCA MACF1 ALDH1A1 SOD3	9.59e-05	192	170	6	d22c1135867bcb9076435e2c6eb1cc1248990d0c
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	TNPO2 WDR6 ANKRD11 KMT2A WDR90 SRRM2	9.59e-05	192	170	6	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	droplet-Lung-nan-18m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTK7 ANGPTL4 PRKCA MACF1 ALDH1A1 SOD3	9.59e-05	192	170	6	c09966f4d63a739a56db4df7e0e0ee9ecacd21ad
Disease	obsolete Mendelian syndromes with cleft lip/palate	SH3BP4 SVIL PKN1 LRRC7 FHIT	1.69e-07	23	167	5	MONDO_0015335
Disease	Schizophrenia	IPO5 PDE4A ACHE XRCC1 SLC6A12 HPGDS GPR153 PITX3 STON2 KMT2A PRKCA OXSR1 ALDH1A1 HTR3B CTNNB1 C9orf72 MED12 TP53 CNTF	6.91e-07	883	167	19	C0036341
Disease	Adenocarcinoma of large intestine	PTK7 PRKCA PRKCB EEF2K PKN1 CTNNB1 TP53	1.28e-06	96	167	7	C1319315
Disease	percent glycated albumin	GCKR PRKCA	9.52e-05	3	167	2	EFO_0009304
Disease	Adrenocortical carcinoma	CTNNB1 MED12 TP53	1.36e-04	18	167	3	C0206686
Disease	Psychotic Disorders	GRIN1 HPGDS PRKCA C9orf72 MED12	2.80e-04	101	167	5	C0033975
Disease	YKL40 measurement, cerebrospinal fluid biomarker measurement	EYS SIPA1L2	3.15e-04	5	167	2	EFO_0004869, EFO_0006794
Disease	eosinophilic esophagitis	CCDC71L WDR36 ST6GAL1 STAT6 KLHL33 FHIT	3.43e-04	163	167	6	EFO_0004232
Disease	platelet component distribution width	CCDC71L MYCT1 SYNE1 SLFN14 JMY ASAP1 CTDSP2 NCOR2 MEIOC SVIL MOV10L1 MACF1 GAA	3.85e-04	755	167	13	EFO_0007984
Disease	extracellular superoxide dismutase [Cu-Zn] measurement	TBC1D19 SOD3	4.71e-04	6	167	2	EFO_0022018
Disease	colorectal cancer (biomarker_via_orthology)	CTNNB1 TP53	4.71e-04	6	167	2	DOID:9256 (biomarker_via_orthology)
Disease	Fuchs' endothelial dystrophy (is_implicated_in)	LOXHD1 AGBL1	4.71e-04	6	167	2	DOID:11555 (is_implicated_in)
Disease	Schizoaffective Disorder	GRIN1 PRKCA C9orf72	5.84e-04	29	167	3	C0036337
Disease	Epileptic encephalopathy	NEDD4L GRIN1 KCTD3	6.46e-04	30	167	3	C0543888
Disease	Alcoholic Intoxication	ST6GAL1 ALDH1A1 TP53	7.83e-04	32	167	3	C0001969
Disease	Prostatic Neoplasms	DCAF6 ACHE XRCC1 LRP1B DHDH PITX3 KMT2A CTNNB1 FHIT MED12 TP53	8.07e-04	616	167	11	C0033578
Disease	Malignant neoplasm of prostate	DCAF6 ACHE XRCC1 LRP1B DHDH PITX3 KMT2A CTNNB1 FHIT MED12 TP53	8.07e-04	616	167	11	C0376358
Disease	Urologic Neoplasms	FHIT TP53	8.72e-04	8	167	2	C0042076
Disease	Cancer of Urinary Tract	FHIT TP53	8.72e-04	8	167	2	C0751571
Disease	Acute erythroleukemia - M6a subtype	KMT2A TP53	8.72e-04	8	167	2	C2930975
Disease	Acute myeloid leukemia FAB-M6	KMT2A TP53	8.72e-04	8	167	2	C2930976
Disease	Acute erythroleukemia - M6b subtype	KMT2A TP53	8.72e-04	8	167	2	C2930977
Disease	Acute erythroleukemia	KMT2A TP53	8.72e-04	8	167	2	C2930974
Disease	endometrial carcinoma (is_marker_for)	NCOR2 PRKCA TP53	9.37e-04	34	167	3	DOID:2871 (is_marker_for)
Disease	HEPATOCELLULAR CARCINOMA	CTNNB1 TP53	1.12e-03	9	167	2	114550
Disease	Adult Hepatocellular Carcinoma	CTNNB1 TP53	1.12e-03	9	167	2	C0279607
Disease	Hepatocellular carcinoma	CTNNB1 TP53	1.12e-03	9	167	2	cv:C2239176
Disease	Glioma	CTNNB1 TP53	1.12e-03	9	167	2	cv:C0017638
Disease	Nonsyndromic Deafness	TNC LOXHD1 STRC OTOG	1.17e-03	81	167	4	C3711374
Disease	leptin measurement	GCKR LRP1B CD93 CPVL	1.17e-03	81	167	4	EFO_0005000
Disease	response to radiation, prostate carcinoma, erectile dysfunction	LRP1B PTGFRN AOPEP	1.20e-03	37	167	3	EFO_0001663, EFO_0004234, GO_0009314
Disease	glaucoma (is_implicated_in)	WDR36 CNTF	1.39e-03	10	167	2	DOID:1686 (is_implicated_in)
Disease	Adrenal Gland Neoplasms	CTNNB1 TP53	1.69e-03	11	167	2	C0001624
Disease	invasive ductal carcinoma (is_implicated_in)	XRCC1 FHIT	1.69e-03	11	167	2	DOID:3008 (is_implicated_in)
Disease	Adrenal Cancer	CTNNB1 TP53	1.69e-03	11	167	2	C0750887
Disease	Neurodevelopmental Disorders	PTK7 ANKRD11 KMT2A CTNNB1	1.95e-03	93	167	4	C1535926
Disease	Intestinal Neoplasms	PRKCA CTNNB1	2.02e-03	12	167	2	C0021841
Disease	Intestinal Cancer	PRKCA CTNNB1	2.02e-03	12	167	2	C0346627
Disease	Malignant neoplasm of kidney	HPGDS HLTF TP53	2.12e-03	45	167	3	C0740457
Disease	Cardiotoxicity	BMP2 TP53	2.38e-03	13	167	2	C0876994
Disease	prostate carcinoma (is_implicated_in)	STAT6 PRKCA	2.38e-03	13	167	2	DOID:10286 (is_implicated_in)
Disease	gallbladder cancer (is_implicated_in)	XRCC1 LRP1B	2.38e-03	13	167	2	DOID:3121 (is_implicated_in)
Disease	testosterone measurement	DIP2B PDE4A ACHE ETF1 GCKR PKDREJ C2CD2 ZC3H7A NCOR2 AOPEP MCM9 PRKCA MACF1 FHIT MED12 TP53	2.47e-03	1275	167	16	EFO_0004908
Disease	L2 Acute Lymphoblastic Leukemia	XRCC1 KMT2A TP53	2.87e-03	50	167	3	C0023453
Disease	cholesteryl esters to total lipids in IDL percentage	GCKR ANGPTL4 MACF1	2.87e-03	50	167	3	EFO_0022247
Disease	urate measurement, bone density	CCDC71L SYNE1 PREPL ENTPD4 EYS KIDINS220 MOV10L1 USP40 ANKRD11 FHIT	2.87e-03	619	167	10	EFO_0003923, EFO_0004531
Disease	melanoma	TNC LRP1B ADAMTS20 ALDH1A1 CTNNB1 TP53	2.97e-03	248	167	6	C0025202
Disease	disease recurrence, colon carcinoma	BMP2 MACF1 SOD3	3.04e-03	51	167	3	EFO_0004952, EFO_1001950
Disease	Osteopenia	SLC5A6 ANKRD11	3.19e-03	15	167	2	C0029453
Disease	nasopharynx carcinoma (is_implicated_in)	XRCC1 TP53	3.19e-03	15	167	2	DOID:9261 (is_implicated_in)
Disease	Hypertriglyceridemia	GCKR ANGPTL4	3.19e-03	15	167	2	C0020557
Disease	Childhood Acute Lymphoblastic Leukemia	XRCC1 KMT2A TP53	3.21e-03	52	167	3	C0023452
Disease	alcohol use disorder (is_implicated_in)	GRIN1 HTR3B	3.63e-03	16	167	2	DOID:1574 (is_implicated_in)
Disease	Seasonal Affective Disorder	PDE4A NR1D1	3.63e-03	16	167	2	C0085159
Disease	body surface area	GCKR NCOR2 AOPEP ANKRD11 MACF1 FHIT CTDSPL EIF2AK3 TP53 ECE2	3.76e-03	643	167	10	EFO_0022196
Disease	severe acute respiratory syndrome, COVID-19	ST6GAL1 LRP1B EYS FBXO10 KCND3 PRKCA FHIT SIPA1L2	4.08e-03	447	167	8	EFO_0000694, MONDO_0100096
Disease	response to radiation, Urinary retention	LRP1B FHIT	4.10e-03	17	167	2	GO_0009314, HP_0000016
Disease	Antihistamine use measurement	WDR36 STAT6	4.10e-03	17	167	2	EFO_0009943
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	DIP2B SRRM2	4.10e-03	17	167	2	DOID:0060307 (is_implicated_in)
Disease	non-melanoma skin carcinoma	IPO5 GUCY2F ANKRD11 CPVL EIF2AK3 TP53	4.10e-03	265	167	6	EFO_0009260
Disease	cancer (implicated_via_orthology)	IPO5 KANK4 MACF1 CTNNB1 FGR TP53	4.33e-03	268	167	6	DOID:162 (implicated_via_orthology)
Disease	prostate cancer (is_implicated_in)	XRCC1 BMP2 FHIT TP53	4.47e-03	117	167	4	DOID:10283 (is_implicated_in)
Disease	cholesteryl esters to total lipids in large HDL percentage	GCKR NCOR2 ANGPTL4	4.59e-03	59	167	3	EFO_0022248
Disease	ischemia (biomarker_via_orthology)	PRKCA TP53	4.59e-03	18	167	2	DOID:326 (biomarker_via_orthology)
Disease	squamous cell carcinoma (is_implicated_in)	FHIT TP53	4.59e-03	18	167	2	DOID:1749 (is_implicated_in)
Disease	Hemangiosarcoma	CTNNB1 TP53	4.59e-03	18	167	2	C0018923
Disease	immature platelet measurement	CCDC71L SLFN14 ASAP1 SVIL	4.75e-03	119	167	4	EFO_0803541
Disease	protein-glutamine gamma-glutamyltransferase e measurement	NEDD4L GCKR SLC5A6	4.81e-03	60	167	3	EFO_0020690
Disease	triglycerides to total lipids in large HDL percentage	GCKR NCOR2 ANGPTL4	4.81e-03	60	167	3	EFO_0022330
Disease	cholesterol to total lipids in IDL percentage	GCKR ANGPTL4 MACF1	4.81e-03	60	167	3	EFO_0022233
Disease	colorectal cancer (is_implicated_in)	XRCC1 LRP1B CTNNB1 TP53	5.03e-03	121	167	4	DOID:9256 (is_implicated_in)
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	XRCC1 KMT2A TP53	5.04e-03	61	167	3	C1961102
Disease	response to methotrexate, neurotoxicity	MACF1 PKN1	5.11e-03	19	167	2	EFO_0011057, GO_0031427
Disease	sphingomyelin measurement	DIP2B CACNB3 GCKR ANGPTL4 ANKRD11 KANK4	5.16e-03	278	167	6	EFO_0010118
Disease	response to COVID-19 vaccine, SARS-CoV-2 neutralizing antibody measurement	C9orf72 FHIT	5.66e-03	20	167	2	EFO_0803359, EFO_0803362

Protein segments in the cluster

Peptide	Gene	Start	Entry
ASSRFLIEMDDPAWL	URB2	981	Q14146
MMRWNFSPEDLSSIF	nan	1	Q6ZRG5
SWDDFMELGRSIPDT	ACSBG2	196	Q5FVE4
FEGTEMWNPNRELSE	ACHE	111	P22303
WEARELMPQDNFTLT	ERV3-1	306	Q14264
RATEVEMSWDSFNRG	AVIL	146	O75366
KSPRFASWDEMNVLA	ANGPTL4	31	Q9BY76
DSWDSPVTDYRDMKS	ANKRD11	856	Q6UB99
MPSDEASESSRQAWT	CACNB3	401	P54284
DKRSNSSWLEEFSME	CACNA1E	2026	Q15878
SSWLEEFSMERSSEN	CACNA1E	2031	Q15878
LFQWDQDRESMETVP	EIF2AK3	161	Q9NZJ5
EMDFPASAWNREALR	APOBEC4	161	Q8WW27
EFLSWNSSMFDEIRE	HTR3B	91	O95264
KDRSIAVWDMASPTD	BTRC	401	Q9Y297
FLMSLDLESRDQAWS	FBXO10	291	Q9UK96
DSYSWVPERAESRAM	CD93	626	Q9NPY3
LSEMLYTDRPDWQSV	SPECC1	1041	Q5M775
FQIGSPWRTMDASER	ALDH1A1	71	P00352
PEFSDAHMTWLNFVR	C1QTNF12	66	Q5T7M4
METWSSNDLATERPF	AOPEP	351	Q8N6M6
SDMLSRWFEEASEVA	DCAF6	346	Q58WW2
ASRWESFDVTPAVMR	BMP2	201	P12643
FCDPLMSWTDLFSNE	ELF5	26	Q9UKW6
SFNIPLEERSDMFTW	ADAMTS20	836	P59510
DAWDVDAIFCPRMSA	AGBL1	466	Q96MI9
ARWPLDTDADMVVSV	PADI1	66	Q9ULC6
SAAAMESAQSSRLPW	RFX5	486	P48382
MSEDSSALPWSINRD	OXSR1	1	O95747
YQMSSEADDWCIPSR	PDK4	386	Q16654
SWMPRETVIFASDVR	MEIOB	221	Q8N635
GRPMWDNEFSTIATS	NOX1	506	Q9Y5S8
SAELASMELNESSRW	NCOR2	601	Q9Y618
SLFRTEPMAWNETAD	CTNNB1	681	P35222
DPDRMFVELSNSSWS	DCAF1	291	Q9Y4B6
VTEDWFSDISPQTMR	KIDINS220	926	Q9ULH0
DWEEMAPLSQARSLF	KLHL33	301	A6NCF5
PSLSFRQTMWRAFEN	KCND3	161	Q9UK17
DWDANFPRIESASMS	LRP1B	1396	Q9NZR2
LAPFTAEMSDWVDEI	MOV10L1	716	Q9BXT6
KRDPRDWTAQFMEAA	MAGED1	656	Q9Y5V3
SDPSFRSNELSWMSF	EYS	2716	Q5T1H1
MSFALEETLESDWVA	JMY	1	Q8N9B5
IWDASSMTLVDKFNP	NEDD1	16	Q8NHV4
SLYEAMEQTWRLDPE	FGR	486	P09769
QDPVAWNSTFEMLSR	MGAM2	1546	Q2M2H8
DRLPMSDTFTDNWTD	LRRC7	756	Q96NW7
MAAAAVSESWPELEL	LRRC47	1	Q8N1G4
IVDTLDDFMSCFPWA	HPGDS	91	O60760
SPADFWEIALSSKMA	LOXHD1	1386	Q8IVV2
PAITVMDWFEDSRLD	NCCRP1	176	Q6ZVX7
SNMTLRDRDFPWTTT	CPVL	131	Q9H3G5
QALAPSMDWLEFLSF	ECE2	381	P0DPD6
TSPRDEWVFADMDLL	PCNX3	1621	Q9H6A9
NREEADMWTTFRPRS	FOXO4	246	P98177
AFRMWSEVTPLDFRE	MMP21	201	Q8N119
AWEASPAQESLEVMA	PDE4A	751	P27815
EEEKSDSMPLYSNWR	FRYL	1541	O94915
FSSLRADASAPWMAL	GPR153	266	Q6NV75
RPDASEEDSFQWMSR	DIP2B	866	Q9P265
TDVMQESRFSSATWP	MACF1	246	O94854
SSEDVRWDTFPLGRM	LAS1L	641	Q9Y4W2
SESNMRWAPEFMIDT	MED12	1011	Q93074
DWDLTSRNDFMGSLS	PRKCB	246	P05771
PEMQTLAGAFDSDRW	NLRP5	261	P59047
EADWSPDMLADRFLQ	MIEF1	396	Q9NQG6
DDLMLSPDDIEQWFT	TP53	41	P04637
DDDPQISYMISAWAR	IPO5	596	O00410
NSMWASLSSPDAEAV	INF2	581	Q27J81
RTDFSWDGINLSMED	FAM131B	21	Q86XD5
VSMARNDPIEDWSST	GCKR	211	Q14397
TVQEIWEDFSMSFTP	NR1D1	431	P20393
WEDFSMSFTPAVREV	NR1D1	436	P20393
PASWRSEEEMAAEAA	FHIT	126	P49789
TNIEADLRADPSWLM	IGSF10	416	Q6WRI0
DHTTDSWEALQPMTY	KLHL21	396	Q9UJP4
ADPDFASEVMSVSDW	KLHL22	611	Q53GT1
MNSVERYDPSKDSWE	KLHL28	446	Q9NXS3
NTPDLMWEEEFTFEL	C2CD2	306	Q9Y426
QIRPWNLSDSDFVMD	CPEB3	526	Q8NE35
SPMADLFVVWARCED	GCDH	216	Q92947
TFSSDWEIQEDSRLM	CCDC3	171	Q9BQI4
TPREAFALWQMTAED	COL20A1	911	Q9P218
VPVQSWFDDMTDTEL	CTDSPL	236	O15194
VPVQSWFDDMADTEL	CTDSP2	231	O14595
ERYSLTLWQAASDPM	FAM151A	266	Q8WW52
TLWQAASDPMSVEDL	FAM151A	271	Q8WW52
MPTFAAWEAASELHS	CALHM5	256	Q8N5C1
MPVASTDQWSELTEA	CNTF	56	P26441
SEEESSMEELLWTAP	GUCY2F	701	P51841
TWDRTPVSMAASFED	GFOD2	326	Q3B7J2
FSSRDSLWNRMPDQI	ASAP1	11	Q9ULH1
DMEVRWFRSQFSPAV	BTN2A1	61	Q7KYR7
FDTPEAIWSSEMRRL	DNAJC13	1196	O75165
WIDMNEPSNFIRGSE	GAA	516	P10253
ALENFSRASMSDTWD	CEP192	796	Q8TEP8
MEAIWTRFFPASEAL	DHDH	121	Q9UQ10
SSMTSDEPQRCFVWD	NSMAF	841	Q92636
EAEEREWYPSLATMQ	GADD45GIP1	86	Q8TAE8
PLASAETNEDMAVVW	KANK4	866	Q5T7N3
EEEESNFSSPLMLWL	KMT2A	3636	Q03164
RSTEFMSSDAELWSF	CCDC71L	66	Q8N9Z2
TVALWRMDPDKFDDT	DCAF12L1	216	Q5VU92
QFSVAMADDSLWKPL	HEATR1	2051	Q9H583
HWPVFSDLDNMASRD	EEF2K	411	O00418
LSAASRVFLMDPAWN	HLTF	921	Q14527
TSRQTLMWIPDSFFS	KCTD3	31	Q9Y597
YPDMSTREEIAVWTN	PITX3	86	O75364
LTAFWRATSEEDMAQ	C9orf72	336	Q96LT7
TSMNWDTVPTREERY	LRRC72	256	A6NJI9
LEEMLWFFRVEDASP	SLC51B	21	Q86UW2
AEAPDSVAMSSWERR	OTOG	86	Q6ZRI0
RAIDQASFTTSMEWD	OIP5	26	O43482
SLDWFDFMATHQSEP	MCM9	741	Q9NXL9
ADDVRPEVTWSFSRM	PTGFRN	306	Q9P2B2
EDRVDFMERSPNISW	SYVN1	121	Q86TM6
DLEEQWMYPSRSDHS	MEIOC	231	A2RUB1
VFAEAPDSWIMKDNS	SLFN14	321	P0C7P3
ASLEAVEVPSMASSW	SRRM2	1291	Q9UQ35
LLMENISSWRSFADA	SH3BP4	761	Q9P0V3
TNMFPSWEHREDIAE	SVIL	2116	O95425
ATDSSSMWSPEEQDR	SYT16	321	Q17RD7
SIDFQTEMSRSLDWL	SYNE1	4886	Q8NF91
PWQDDDISDIMFVTT	TEDDM1	186	Q5T9Z0
DWDRTTRNDFMGSLS	PRKCA	246	P17252
SDPENTTWADIEAMV	NBR1	21	Q14596
WFPEFSEARAIMLSR	SLC5A6	386	Q9Y289
DVPDLSFMCSWRDAL	TAF1C	21	Q15572
PENFWEDLIMSFTVS	MYCT1	61	Q8N699
PSEFTWDAQKRATMR	PKDREJ	766	Q9NTG1
RTPRSSSAAALWMEE	ENTPD4	591	Q9Y227
FENFTSPVMEFWERR	SLC6A12	181	P48065
APSMGSLRNEFWFSD	SIPA1L2	1536	Q9P2F8
SMVEVTDFPFNTSEW	ST6GAL1	151	P15907
MASDAVQSEPRSWSL	PKN1	1	Q16512
LSRESPLMSMDSWFS	STARD9	1326	Q9P2P6
FPAAWSATQIAEMEL	STRC	1471	Q7RTU9
EVEMEAISWQASSPA	STON2	201	Q8WXE9
FISNDMRLGSWFDPS	BRINP2	531	Q9C0B6
VIPSDTDFLDTWEAM	AKR1E2	141	Q96JD6
LAWVAAEVPEESSRM	ASPRV1	71	Q53RT3
DVRTARWMFETQPLD	XIRP2	591	A4UGR9
SAQARAPSVMRLWDF	WDR90	426	Q96KV7
LEASPTMSLWEFEDS	ZC3H12A	11	Q5D1E8
PMDVRQWVDTDDTSS	RPA2	101	P15927
EPNSDSAEWIRDMYA	SOD3	26	P08294
ILWDNAFSEMDRVPF	STAT6	426	P42226
ASVDSASMEDFWREI	ARHGAP28	71	Q9P2N2
VASWVSPKDDLRDMF	TNPO2	846	O14787
VSDITPESFNLSWMA	TNC	1446	P24821
MDSPWDELALAFSRT	TMEM38B	1	Q9NVV0
PDMESDIRSWELFLS	TTC3	1681	P53804
RTAADTPAIMNWDLF	PREPL	326	Q4J6C6
MDWVNFTSAFRAATP	UPK1A	166	O00322
MDALEDYVWPRATSE	WDR6	1	Q9NNW5
SFAHSPEEREVWTYM	ZC3H7A	791	Q8IWR0
TAQEWDPSFEEALMD	XRCC1	586	P18887
MAVETLSPDWEFDRV	WASHC4	1	Q2M389
QTDDLLRMTESWFSS	PSMD5	376	Q16401
LRMTESWFSSLSRDP	PSMD5	381	Q16401
TDDPNWDSYATTMRT	TEX26	21	Q8N6G2
WSFVETLDSPTMEAY	RIPOR1	1046	Q6ZS17
WNEMGTDEPDLSLFR	TBC1D19	136	Q8N5T2
RWMSPEAILEGDFST	PTK7	971	Q13308
DLTDSFGWTSNEEMR	USP40	116	Q9NVE5
MWFTPFQAEEIDTDL	VIRMA	1531	Q69YN4
TFAQEMLVDRHPSWE	WDR87	1271	Q6ZQQ6
SFGRTLEDLTEDSMW	TGM6	316	O95932
DMSWPEEMSFIANSS	USP32	706	Q8NFA0
NDMAFSPDGRWLISA	WDR36	626	Q8NI36
SMDFSQEEWELLEPA	ZNF554	51	Q86TJ5
MADDPSAADRNVEIW	ETF1	1	P62495
MTWARSKALDPEDSE	AK7	156	Q96M32
EEEDALTLSSAMWFS	GRIN1	596	Q05586
WHRPSLMDVSSESDN	NEDD4L	221	Q96PU5