Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nicotinic acid receptor activity	HCAR2 HCAR3	7.12e-05	2	169	2	GO:0070553
Domain	Ig_I-set	CHL1 ADAMTSL1 IGFN1 MYOM1 L1CAM OBSCN NCAM1 IGSF10 LINGO1 IGFBP7 CD22 CLMP IGSF9B	1.77e-08	190	168	13	IPR013098
Domain	I-set	CHL1 ADAMTSL1 IGFN1 MYOM1 L1CAM OBSCN NCAM1 IGSF10 LINGO1 IGFBP7 CD22 CLMP IGSF9B	1.77e-08	190	168	13	PF07679
Domain	IGc2	CHL1 ADAMTSL1 IGFN1 MYOM1 PECAM1 L1CAM OBSCN NCAM1 IGSF10 LINGO1 CD22 CLMP IGSF9B	2.15e-07	235	168	13	SM00408
Domain	Ig_sub2	CHL1 ADAMTSL1 IGFN1 MYOM1 PECAM1 L1CAM OBSCN NCAM1 IGSF10 LINGO1 CD22 CLMP IGSF9B	2.15e-07	235	168	13	IPR003598
Domain	IG	CHL1 ADAMTSL1 IGFN1 MYOM1 PECAM1 L1CAM OBSCN NCAM1 IL18R1 HAPLN1 IGSF10 LINGO1 IGFBP7 CD22 CLMP IGSF9B	1.35e-06	421	168	16	SM00409
Domain	Ig_sub	CHL1 ADAMTSL1 IGFN1 MYOM1 PECAM1 L1CAM OBSCN NCAM1 IL18R1 HAPLN1 IGSF10 LINGO1 IGFBP7 CD22 CLMP IGSF9B	1.35e-06	421	168	16	IPR003599
Domain	IG_LIKE	CHL1 ADAMTSL1 IGFN1 MYOM1 PECAM1 L1CAM OBSCN NCAM1 IL18R1 HAPLN1 IGSF10 LINGO1 IGFBP7 CD22 CLMP IGSF9B	9.57e-06	491	168	16	PS50835
Domain	Ig-like_dom	CHL1 ADAMTSL1 IGFN1 MYOM1 PECAM1 L1CAM OBSCN NCAM1 IL18R1 HAPLN1 IGSF10 LINGO1 IGFBP7 CD22 CLMP IGSF9B	1.29e-05	503	168	16	IPR007110
Domain	fn3	CHL1 IGFN1 MYOM1 L1CAM OBSCN NCAM1 PTPRB IGSF9B SORL1	1.62e-05	162	168	9	PF00041
Domain	-	CHL1 ADAMTSL1 IGFN1 MYOM1 PECAM1 L1CAM OBSCN NCAM1 IL18R1 HAPLN1 IGSF10 PTPRB LINGO1 IGFBP7 CD22 CLMP IGSF9B SORL1	3.06e-05	663	168	18	2.60.40.10
Domain	FN3	CHL1 IGFN1 MYOM1 L1CAM OBSCN NCAM1 PTPRB IGSF9B SORL1	4.62e-05	185	168	9	SM00060
Domain	Ig-like_fold	CHL1 ADAMTSL1 IGFN1 MYOM1 PECAM1 L1CAM OBSCN NCAM1 IL18R1 HAPLN1 IGSF10 PTPRB LINGO1 IGFBP7 CD22 CLMP IGSF9B SORL1	6.90e-05	706	168	18	IPR013783
Domain	ARPC1	ARPC1A ARPC1B	8.04e-05	2	168	2	IPR017383
Domain	HCAR2/3_rcpt	HCAR2 HCAR3	8.04e-05	2	168	2	IPR028017
Domain	FN3	CHL1 IGFN1 MYOM1 L1CAM OBSCN NCAM1 PTPRB IGSF9B SORL1	8.12e-05	199	168	9	PS50853
Domain	FN3_dom	CHL1 IGFN1 MYOM1 L1CAM OBSCN NCAM1 PTPRB IGSF9B SORL1	1.18e-04	209	168	9	IPR003961
Domain	WD_REPEATS_1	ARPC1A GEMIN5 NBEA ARPC1B PWP1 EML5 RRP9 EIF3B HERC2 WDR17	2.17e-04	278	168	10	PS00678
Domain	WD_REPEATS_2	ARPC1A GEMIN5 NBEA ARPC1B PWP1 EML5 RRP9 EIF3B HERC2 WDR17	2.23e-04	279	168	10	PS50082
Domain	WD_REPEATS_REGION	ARPC1A GEMIN5 NBEA ARPC1B PWP1 EML5 RRP9 EIF3B HERC2 WDR17	2.23e-04	279	168	10	PS50294
Domain	Glyco_trans_43	B3GAT3 B3GAT1	2.40e-04	3	168	2	IPR005027
Domain	RGS-like_dom	ARHGEF12 ARHGEF1	2.40e-04	3	168	2	IPR015212
Domain	RGS-like	ARHGEF12 ARHGEF1	2.40e-04	3	168	2	PF09128
Domain	Glyco_transf_43	B3GAT3 B3GAT1	2.40e-04	3	168	2	PF03360
Domain	Dynein_heavy_chain_D4_dom	DNAH12 DNAH5 DNAH6	2.42e-04	14	168	3	IPR024317
Domain	Dynein_heavy_dom-2	DNAH12 DNAH5 DNAH6	2.42e-04	14	168	3	IPR013602
Domain	DHC_N2	DNAH12 DNAH5 DNAH6	2.42e-04	14	168	3	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH12 DNAH5 DNAH6	2.42e-04	14	168	3	IPR011704
Domain	AAA_8	DNAH12 DNAH5 DNAH6	2.42e-04	14	168	3	PF12780
Domain	AAA_5	DNAH12 DNAH5 DNAH6	2.42e-04	14	168	3	PF07728
Domain	DHC_fam	DNAH12 DNAH5 DNAH6	3.00e-04	15	168	3	IPR026983
Domain	Dynein_heavy	DNAH12 DNAH5 DNAH6	3.00e-04	15	168	3	PF03028
Domain	Dynein_heavy_dom	DNAH12 DNAH5 DNAH6	3.00e-04	15	168	3	IPR004273
Domain	GDS_CDC24_CS	OBSCN ARHGEF12 ARHGEF1 NGEF	4.06e-04	39	168	4	IPR001331
Domain	Neurofascin/L1/NrCAM_C	CHL1 L1CAM	4.77e-04	4	168	2	IPR026966
Domain	Bravo_FIGEY	CHL1 L1CAM	4.77e-04	4	168	2	PF13882
Domain	IGv	OBSCN HAPLN1 IGSF10 CLMP IGSF9B	5.76e-04	75	168	5	SM00406
Domain	Apc4_WD40_dom	GEMIN5 EML5 WDR17	7.28e-04	20	168	3	IPR024977
Domain	ANAPC4_WD40	GEMIN5 EML5 WDR17	7.28e-04	20	168	3	PF12894
Domain	WD40_repeat	ARPC1A GEMIN5 NBEA ARPC1B PWP1 EML5 RRP9 HERC2 WDR17	8.15e-04	272	168	9	IPR001680
Domain	-	B3GAT3 GYG1 B3GAT1 GALNT6 PLOD2	8.19e-04	81	168	5	3.90.550.10
Domain	FAD-bd	MICAL1 MICAL3	1.18e-03	6	168	2	IPR002938
Domain	FAD_binding_3	MICAL1 MICAL3	1.18e-03	6	168	2	PF01494
Domain	Nucleotide-diphossugar_trans	B3GAT3 GYG1 B3GAT1 GALNT6 PLOD2	1.19e-03	88	168	5	IPR029044
Domain	WD40_repeat_dom	ARPC1A GEMIN5 NBEA LRRK1 ARPC1B PWP1 EML5 RRP9 WDR17	1.50e-03	297	168	9	IPR017986
Domain	RNase_Zc3h12a	ZC3H12B ZC3H12C	1.64e-03	7	168	2	PF11977
Domain	DUF3585	MICAL1 MICAL3	1.64e-03	7	168	2	IPR022735
Domain	DUF3585	MICAL1 MICAL3	1.64e-03	7	168	2	PF12130
Domain	RNase_Zc3h12_NYN	ZC3H12B ZC3H12C	1.64e-03	7	168	2	IPR021869
Domain	E2F	E2F7 E2F8	2.17e-03	8	168	2	IPR015633
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYH10 UTP14A NUP98 GEMIN5 CCT2 FRYL URB2 TASOR2 DHX30 PWP1 RIF1 KARS1 RRP9 PRMT5 SYNE2 XRN1 HERC2	3.08e-08	653	172	17	22586326
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MPP3 TPST2 FRAS1 RTL6 LZTR1 L1CAM OBSCN LAMA5 GEMIN5 FRYL LRRK1 DUS1L MAP3K5 DHX30 SH3BP4 ITPR2 CDK5R1 WIZ MICAL3 LRRC14 HERC2 RASAL1	3.26e-08	1105	172	22	35748872
Pubmed	Proteolytic cleavage of transmembrane cell adhesion molecule L1 by extracellular matrix molecule Reelin is important for mouse brain development.	CHL1 L1CAM NCAM1 CUX1	1.19e-07	10	172	4	29127326
Pubmed	The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections.	CHL1 MICAL1 L1CAM NCAM1	2.77e-07	12	172	4	25007825
Pubmed	E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1.	PECAM1 E2F7 E2F8	4.74e-07	4	172	3	22903062
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MICAL1 MYH10 NRDC ARPC1A L1CAM ARHGEF12 GEMIN5 ZC3HC1 NCAM1 NBEA CCT2 ARPC1B DHX30 HAPLN1 ITPR2 KARS1 ARHGEF1 PRMT5 NGEF XRN1 MICAL3 DNAH6 RASAL1	6.91e-07	1431	172	23	37142655
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CFAP47 PDE3B OBSCN SLC28A3 NBEA ITPR2 TMCO4 IGSF10 KARS1 DENND6A LOXHD1 WIZ PDLIM1 SYDE2 PRMT5 IGSF9B	8.83e-07	736	172	16	29676528
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	FRAS1 PDE3B NRDC UTP14A PEX1 URGCP SH3BP4 PWP1 ARHGEF1 XRN1 MARF1 AP1M1 MICAL3 GALNT6 SORL1	9.44e-07	650	172	15	38777146
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	SLC25A46 IBA57 PDE3B MYH10 PTPMT1 DIABLO UTP14A NUP98 PEX1 CCT2 ZDBF2 AHCYL2 TIMMDC1 DHX30 ITPR2 WIZ CNIH4 RRP9 SYNE2 ALAS1 EXOG HERC2 CUX1	1.47e-06	1496	172	23	32877691
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	UTP14A NUP98 ZC3HC1 NCAM1 NBEA CCT2 TASOR2 SH3BP4 CEP350 RIF1 DENND6A WIZ SYDE2 XRN1 CUX1 NOL8	1.78e-06	777	172	16	35844135
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	DNAJB11 PTPMT1 NAAA MANBA L1CAM NUP98 LAMA5 GEMIN5 CCT2 KARS1 PRMT5 EIF3B PLOD2 SORL1	2.49e-06	613	172	14	22268729
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	ARHGEF12 CCT2 ARHGEF1 PRMT5 SYNE2 EIF3B DNAH6 CUX1	4.57e-06	187	172	8	26460568
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PDE3B MYH10 ITCH OBSCN FRYL AHCYL2 KCNIP3 UBN2 AR TASOR2 SH3BP4 RLF TMCO4 PPARGC1B PTPRB NGEF SLX4IP MICAL3 IGSF9B CSMD1 CUX1 CAP2	4.80e-06	1489	172	22	28611215
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	TPST2 DNAJB11 FRAS1 NAAA MANBA L1CAM LAMA5 SMOC1 B3GAT3 ITPR2 IGSF10 IGFBP7 PDLIM1 CNIH4 PRMT5 EBP TXNDC16 PLOD2 SORL1	8.67e-06	1201	172	19	35696571
Pubmed	Basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome.	FRAS1 PECAM1 LAMA5	1.39e-05	10	172	3	15623520
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	CHL1 PECAM1 OBSCN IGSF10 LINGO1 CD22 CLMP	1.71e-05	162	172	7	25826454
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	FRAS1 MANBA LAMA5 HAPLN1 GALNT6 PLOD2 SORL1	1.86e-05	164	172	7	32409323
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	DNAJB11 MYH10 LZTR1 PTPMT1 NUP98 NBEA CCT2 ITPR2 CEP350 RIF1 KARS1 PTPRB WIZ SYNE2 MICAL3 HERC2 CAP2	1.95e-05	1049	172	17	27880917
Pubmed	Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization.	HCAR2 HCAR3	2.43e-05	2	172	2	28186140
Pubmed	Atypical E2Fs inhibit tumor angiogenesis.	E2F7 E2F8	2.43e-05	2	172	2	28925392
Pubmed	The Immunometabolomic Interface Receptor Hydroxycarboxylic Acid Receptor 2 Mediates the Therapeutic Effects of Dimethyl Fumarate in Autoantibody-Induced Skin Inflammation.	HCAR2 HCAR3	2.43e-05	2	172	2	30154797
Pubmed	Activating signal cointegrator 1 is highly expressed in murine testicular Leydig cells and enhances the ligand-dependent transactivation of androgen receptor.	TRIP4 AR	2.43e-05	2	172	2	12390891
Pubmed	Identification of Serhl, a new member of the serine hydrolase family induced by passive stretch of skeletal muscle in vivo.	SERHL2 SERHL	2.43e-05	2	172	2	11352564
Pubmed	Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential.	ARHGEF12 ARHGEF1	2.43e-05	2	172	2	14712228
Pubmed	The role of HCA2 (GPR109A) in regulating macrophage function.	HCAR2 HCAR3	2.43e-05	2	172	2	23882124
Pubmed	Regionally specific expression of L1 and sialylated NCAM in the retinofugal pathway of mouse embryos.	L1CAM NCAM1	2.43e-05	2	172	2	15022265
Pubmed	Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model.	HCAR2 HCAR3	2.43e-05	2	172	2	36891315
Pubmed	Structural features of a close homologue of L1 (CHL1) in the mouse: a new member of the L1 family of neural recognition molecules.	CHL1 L1CAM	2.43e-05	2	172	2	8921253
Pubmed	Parabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a.	HCAR2 HCAR3	2.43e-05	2	172	2	38007572
Pubmed	Aberrant NK cell associated marker (CD56 and CD57) expression in chronic lymphocytic leukemia.	NCAM1 B3GAT1	2.43e-05	2	172	2	26013700
Pubmed	Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE.	HCAR2 HCAR3	2.43e-05	2	172	2	24691444
Pubmed	Butyrate ameliorates caerulein-induced acute pancreatitis and associated intestinal injury by tissue-specific mechanisms.	HCAR2 HCAR3	2.43e-05	2	172	2	31347703
Pubmed	Loss of GPR109A/HCAR2 induces aging-associated hepatic steatosis.	HCAR2 HCAR3	2.43e-05	2	172	2	30659164
Pubmed	Expression and prognostic relevance of MAGE-C1/CT7 and MAGE-C2/CT10 in osteolytic lesions of patients with multiple myeloma.	MAGEC1 MAGEC2	2.43e-05	2	172	2	20621094
Pubmed	Expression and localization of GPR109A (PUMA-G/HM74A) mRNA and protein in mammalian retinal pigment epithelium.	HCAR2 HCAR3	2.43e-05	2	172	2	19223991
Pubmed	Niacin increases adiponectin and decreases adipose tissue inflammation in high fat diet-fed mice.	HCAR2 HCAR3	2.43e-05	2	172	2	23967184
Pubmed	Involvement of the Niacin Receptor GPR109a in the LocalControl of Glucose Uptake in Small Intestine of Type 2Diabetic Mice.	HCAR2 HCAR3	2.43e-05	2	172	2	26371038
Pubmed	Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease.	HCAR2 HCAR3	2.43e-05	2	172	2	34653248
Pubmed	Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G).	HCAR2 HCAR3	2.43e-05	2	172	2	19136666
Pubmed	G Protein-Coupled Receptor 109A Maintains the Intestinal Integrity and Protects Against ETEC Mucosal Infection by Promoting IgA Secretion.	HCAR2 HCAR3	2.43e-05	2	172	2	33488584
Pubmed	Effect of Cell Adhesion Molecules on the Neurite Outgrowth of Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons.	L1CAM NCAM1	2.43e-05	2	172	2	26990843
Pubmed	Lactate-induced activation of HCA2 improves survival in mice with sepsis.	HCAR2 HCAR3	2.43e-05	2	172	2	30951370
Pubmed	Neural adhesion molecules L1 and CHL1 are survival factors for motoneurons.	CHL1 L1CAM	2.43e-05	2	172	2	15880726
Pubmed	Niacin Ameliorates Hepatic Steatosis by Inhibiting De Novo Lipogenesis Via a GPR109A-Mediated PKC-ERK1/2-AMPK Signaling Pathway in C57BL/6 Mice Fed a High-Fat Diet.	HCAR2 HCAR3	2.43e-05	2	172	2	31858105
Pubmed	Exploring the role of the metabolite-sensing receptor GPR109a in diabetic nephropathy.	HCAR2 HCAR3	2.43e-05	2	172	2	32068460
Pubmed	The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome.	HCAR2 HCAR3	2.43e-05	2	172	2	30657794
Pubmed	Melatonin alleviates titanium nanoparticles induced osteolysis via activation of butyrate/GPR109A signaling pathway.	HCAR2 HCAR3	2.43e-05	2	172	2	34092246
Pubmed	Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis.	PECAM1 PTPRB	2.43e-05	2	172	2	17360632
Pubmed	Specific enzyme complex of beta-1,4-galactosyltransferase-II and glucuronyltransferase-P facilitates biosynthesis of N-linked human natural killer-1 (HNK-1) carbohydrate.	B3GAT3 B3GAT1	2.43e-05	2	172	2	21771787
Pubmed	Molecular identification of high and low affinity receptors for nicotinic acid.	HCAR2 HCAR3	2.43e-05	2	172	2	12522134
Pubmed	Stress downregulates hippocampal expression of the adhesion molecules NCAM and CHL1 in mice by mechanisms independent of DNA methylation of their promoters.	CHL1 NCAM1	2.43e-05	2	172	2	19262122
Pubmed	Neural cell adhesion molecule, NCAM, regulates thalamocortical axon pathfinding and the organization of the cortical somatosensory representation in mouse.	L1CAM NCAM1	2.43e-05	2	172	2	22723769
Pubmed	Developmental expression of neural cell adhesion molecules in the mouse neocortex and olfactory bulb.	L1CAM NCAM1	2.43e-05	2	172	2	1723996
Pubmed	The fourth immunoglobulin-like domain of NCAM contains a carbohydrate recognition domain for oligomannosidic glycans implicated in association with L1 and neurite outgrowth.	L1CAM NCAM1	2.43e-05	2	172	2	8509458
Pubmed	G Protein-Coupled Receptor 109A and Host Microbiota Modulate Intestinal Epithelial Integrity During Sepsis.	HCAR2 HCAR3	2.43e-05	2	172	2	30271409
Pubmed	Misguided axonal projections, neural cell adhesion molecule 180 mRNA upregulation, and altered behavior in mice deficient for the close homolog of L1.	CHL1 NCAM1	2.43e-05	2	172	2	12391163
Pubmed	Niacin fine-tunes energy homeostasis through canonical GPR109A signaling.	HCAR2 HCAR3	2.43e-05	2	172	2	30596513
Pubmed	The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease.	HCAR2 HCAR3	2.43e-05	2	172	2	35320002
Pubmed	GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing.	HCAR2 HCAR3	2.43e-05	2	172	2	16322797
Pubmed	E2F7 Is a Potent Inhibitor of Liver Tumor Growth in Adult Mice.	E2F7 E2F8	2.43e-05	2	172	2	32259305
Pubmed	Nicotinic acid receptor agonists.	HCAR2 HCAR3	2.43e-05	2	172	2	18983141
Pubmed	Gut microbial metabolite butyrate protects against proteinuric kidney disease through epigenetic- and GPR109a-mediated mechanisms.	HCAR2 HCAR3	2.43e-05	2	172	2	31366236
Pubmed	DNA-damage response control of E2F7 and E2F8.	E2F7 E2F8	2.43e-05	2	172	2	18202719
Pubmed	Chromosomal aberrations of cancer-testis antigens in myeloma patients.	MAGEC1 MAGEC2	2.43e-05	2	172	2	24820892
Pubmed	GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice.	HCAR2 HCAR3	2.43e-05	2	172	2	35489706
Pubmed	Universal expression of cell adhesion molecule NCAM in neuroblastoma in contrast to L1: implications for different roles in tumor biology of neuroblastoma?	L1CAM NCAM1	2.43e-05	2	172	2	18972120
Pubmed	MAGE-C1/CT7 and MAGE-C2/CT10 are frequently expressed in multiple myeloma and can be explored in combined immunotherapy for this malignancy.	MAGEC1 MAGEC2	2.43e-05	2	172	2	23180015
Pubmed	CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset.	NCAM1 B3GAT1	2.43e-05	2	172	2	20733159
Pubmed	Deorphanization of GPR109B as a receptor for the beta-oxidation intermediate 3-OH-octanoic acid and its role in the regulation of lipolysis.	HCAR2 HCAR3	2.43e-05	2	172	2	19561068
Pubmed	E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7.	E2F7 E2F8	2.43e-05	2	172	2	15897886
Pubmed	The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival.	HCAR2 HCAR3	2.43e-05	2	172	2	24371223
Pubmed	High dietary niacin may increase prostaglandin formation but does not increase tumor formation in ApcMin/+ mice.	HCAR2 HCAR3	2.43e-05	2	172	2	21774590
Pubmed	Molecular basis for acceptor substrate specificity of the human beta1,3-glucuronosyltransferases GlcAT-I and GlcAT-P involved in glycosaminoglycan and HNK-1 carbohydrate epitope biosynthesis, respectively.	B3GAT3 B3GAT1	2.43e-05	2	172	2	17567734
Pubmed	Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer.	E2F7 E2F8	2.43e-05	2	172	2	27452520
Pubmed	Impairment of sensorimotor gating in mice deficient in the cell adhesion molecule L1 or its close homologue, CHL1.	CHL1 L1CAM	2.43e-05	2	172	2	15533325
Pubmed	E2F7 represses a network of oscillating cell cycle genes to control S-phase progression.	E2F7 E2F8	2.43e-05	2	172	2	22180533
Pubmed	GPR109a Regulates Phenotypic and Functional Alterations in Macrophages and the Progression of Type 1 Diabetes.	HCAR2 HCAR3	2.43e-05	2	172	2	36208084
Pubmed	The role of the C-terminus of the human hydroxycarboxylic acid receptors 2 and 3 in G protein activation using Gα-engineered yeast cells.	HCAR2 HCAR3	2.43e-05	2	172	2	26656756
Pubmed	Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.	HCAR2 HCAR3	2.43e-05	2	172	2	37597514
Pubmed	The Role of GPR109a Signaling in Niacin Induced Effects on Fed and Fasted Hepatic Metabolism.	HCAR2 HCAR3	2.43e-05	2	172	2	33924461
Pubmed	Ketone Body 3-Hydroxybutyrate Ameliorates Atherosclerosis via Receptor Gpr109a-Mediated Calcium Influx.	HCAR2 HCAR3	2.43e-05	2	172	2	33977048
Pubmed	PUMA-G, an IFN-gamma-inducible gene in macrophages is a novel member of the seven transmembrane spanning receptor superfamily.	HCAR2 HCAR3	2.43e-05	2	172	2	11745392
Pubmed	Niacin-induced hyperglycemia is partially mediated via niacin receptor GPR109a in pancreatic islets.	HCAR2 HCAR3	2.43e-05	2	172	2	25622782
Pubmed	GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice.	HCAR2 HCAR3	2.43e-05	2	172	2	33420329
Pubmed	Molecular identification of nicotinic acid receptor.	HCAR2 HCAR3	2.43e-05	2	172	2	12646212
Pubmed	PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect.	HCAR2 HCAR3	2.43e-05	2	172	2	12563315
Pubmed	PRMT5 epigenetically regulates the E3 ubiquitin ligase ITCH to influence lipid accumulation during mycobacterial infection.	ITCH PRMT5	2.43e-05	2	172	2	35658060
Pubmed	Intratumoral Heterogeneity of MAGE-C1/CT7 and MAGE-C2/CT10 Expression in Mucosal Melanoma.	MAGEC1 MAGEC2	2.43e-05	2	172	2	26161400
Pubmed	Deficiency of metabolite sensing receptor HCA2 impairs the salutary effect of niacin in hemorrhagic shock.	HCAR2 HCAR3	2.43e-05	2	172	2	30625381
Pubmed	Ketones and pain: unexplored role of hydroxyl carboxylic acid receptor type 2 in the pathophysiology of neuropathic pain.	HCAR2 HCAR3	2.43e-05	2	172	2	30085883
Pubmed	Nicotinic acid receptor abnormalities in human skin cancer: implications for a role in epidermal differentiation.	HCAR2 HCAR3	2.43e-05	2	172	2	21655214
Pubmed	(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.	HCAR2 HCAR3	2.43e-05	2	172	2	15929991
Pubmed	Heparan/chondroitin sulfate biosynthesis. Structure and mechanism of human glucuronyltransferase I.	B3GAT3 B3GAT1	2.43e-05	2	172	2	10946001
Pubmed	L1-CAM and N-CAM: From Adhesion Proteins to Pharmacological Targets.	L1CAM NCAM1	2.43e-05	2	172	2	26478212
Pubmed	Activation of HCA2 regulates microglial responses to alleviate neurodegeneration in LPS-induced in vivo and in vitro models.	HCAR2 HCAR3	2.43e-05	2	172	2	36991440
Pubmed	Inflammation stimulates niacin receptor (GPR109A/HCA2) expression in adipose tissue and macrophages.	HCAR2 HCAR3	2.43e-05	2	172	2	25320346
Pubmed	The expression of MAGE-C1 and MAGE-C2 in breast cancer and their clinical significance.	MAGEC1 MAGEC2	2.43e-05	2	172	2	26321295
Pubmed	Characterization of recombinant human glucuronyltransferase I involved in the biosynthesis of the glycosaminoglycan-protein linkage region of proteoglycans.	B3GAT3 B3GAT1	2.43e-05	2	172	2	10526176
Pubmed	Nicotinic acid inhibits glucose-stimulated insulin secretion via the G protein-coupled receptor PUMA-G in murine islet β cells.	HCAR2 HCAR3	2.43e-05	2	172	2	21441844
Pubmed	Reconstitution of the human U snRNP assembly machinery reveals stepwise Sm protein organization.	GEMIN5 PRMT5	2.43e-05	2	172	2	26069323
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	CHL1 ADAMTSL1 IGFN1 MYOM1 L1CAM OBSCN NCAM1 IGSF10 LINGO1 IGFBP7 CLMP IGSF9B	6.22e-10	161	118	12	593
GeneFamily	Fibronectin type III domain containing	CHL1 IGFN1 MYOM1 L1CAM OBSCN NCAM1 PTPRB IGSF9B SORL1	1.04e-06	160	118	9	555
GeneFamily	Beta-1,3-glucuronyltransferases	B3GAT3 B3GAT1	1.26e-04	3	118	2	423
GeneFamily	Hydroxy-carboxylic acid receptors	HCAR2 HCAR3	1.26e-04	3	118	2	200
GeneFamily	Dyneins, axonemal	DNAH12 DNAH5 DNAH6	1.72e-04	17	118	3	536
GeneFamily	WD repeat domain containing	ARPC1A GEMIN5 NBEA ARPC1B PWP1 EML5 RRP9 WDR17	3.24e-04	262	118	8	362
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	OBSCN ARHGEF12 ARHGEF1 NGEF	9.10e-04	66	118	4	722
GeneFamily	E2F transcription factors	E2F7 E2F8	1.15e-03	8	118	2	982
GeneFamily	Actin related protein 2/3 complex	ARPC1A ARPC1B	1.48e-03	9	118	2	39
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	ZC3HC1 TRIP4	4.20e-03	15	118	2	26
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	CHL1 MPP3 GABRG1 IGFN1 ATCAY L1CAM SYT6 SYTL2 PEX1 ARHGEF12 LAMA5 FAM114A2 NCAM1 NBEA UBN2 CCDC85A PPARGC1B CDK5R1 PIEZO2 LINGO1 NGEF FAM216A B3GAT1 MICAL3 LPAR2 IGSF9B CSMD1	3.86e-09	1106	172	27	M39071
Coexpression	GSE24210_RESTING_TREG_VS_TCONV_UP	RTL6 NAAA MANBA FRYL E2F8 MAP3K5 CEP350 CD22 SYNE2 FES HERC2	9.37e-08	200	172	11	M7839
Coexpression	GSE29618_MONOCYTE_VS_MDC_DN	MICAL1 CAPG CCT2 IL18R1 SH3BP4 PDLIM1 CD22 SCD HERC2	7.37e-06	200	172	9	M4949
Coexpression	ZHONG_PFC_C3_ASTROCYTE	MICAL1 IBA57 ATCAY L1CAM OBSCN GEMIN5 NCAM1 NBEA UBN2 CDK5R1 NGEF LPAR2	1.08e-05	389	172	12	M39102
Coexpression	YAGI_AML_FAB_MARKERS	TPST2 MYH10 MANBA CAPG LAMA5 NCAM1 PLOD2 SORL1	4.46e-05	194	172	8	M5103
Coexpression	GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_DN	PDE3B UBN2 CEP350 HCAR3 MARF1 ABTB1 ZC3H12C SORL1	4.63e-05	195	172	8	M7310
Coexpression	GSE23321_EFFECTOR_MEMORY_VS_NAIVE_CD8_TCELL_DN	UTP14A GEMIN5 URB2 DHX30 RIF1 RRP9 MAIP1 EIF3B	4.97e-05	197	172	8	M8442
Coexpression	GSE22886_NAIVE_TCELL_VS_NKCELL_DN	ITCH ARHGEF12 NCAM1 FRYL IL18R1 TRIP4 IGFBP7 UEVLD	5.15e-05	198	172	8	M4415
Coexpression	GSE12198_CTRL_VS_HIGH_IL2_STIM_NK_CELL_DN	SERHL2 TPST2 CAPG DUS1L DHX30 IGFBP7 PDLIM1 NGEF	5.53e-05	200	172	8	M7070
Coexpression	GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_180MIN_UP	SERHL2 TPST2 LZTR1 E2F8 MAP3K5 ZNF22 ABTB1 CUX1	5.53e-05	200	172	8	M6623
Coexpression	FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL	SERHL2 MYH10 NAAA SERHL AR MAP3K5 TASOR2 CROT PDLIM1 SCD	6.41e-05	327	172	10	M4008
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBGABA	CHL1 MPP3 GABRG1 ATCAY L1CAM SYTL2 NCAM1 NBEA UBN2 CCDC85A PPARGC1B CDK5R1 EML5 LINGO1 CSMD1	6.57e-05	703	172	15	M39070
Coexpression	FARMER_BREAST_CANCER_APOCRINE_VS_BASAL	SERHL2 NAAA SERHL AR TASOR2 SH3BP4 CROT PDLIM1 SCD FAM216A	6.74e-05	329	172	10	M2631
Coexpression	CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2	MYH10 E2F7 TOGARAM1 LRRK1 CEP350 CDK5R1 DNAH12 LINGO1 NGEF HERC2 DNAH5 DNAH6	6.98e-05	471	172	12	M3062
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MICAL1 RTL6 ATCAY E2F8 ITPR2 IGSF10 SYDE2 MICAL3 IGSF9B PLOD2	2.36e-09	181	172	10	ad30c01290fb98adbd0caed301a584761212c977
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MICAL1 RTL6 ATCAY E2F8 ITPR2 IGSF10 SYDE2 MICAL3 IGSF9B PLOD2	2.36e-09	181	172	10	4e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MICAL1 RTL6 ATCAY E2F8 ITPR2 IGSF10 SYDE2 MICAL3 IGSF9B PLOD2	2.36e-09	181	172	10	3a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 ADAMTSL1 PAMR1 NCAM1 MAP3K5 PIEZO2 IGFBP7 CLMP PID1	6.86e-08	194	172	9	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 ADAMTSL1 PAMR1 NCAM1 MAP3K5 PIEZO2 IGFBP7 CLMP PID1	6.86e-08	194	172	9	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 MAP3K5 PIEZO2 LOXHD1 IGFBP7 CLMP PID1	7.16e-08	195	172	9	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 MAP3K5 PIEZO2 LOXHD1 IGFBP7 CLMP PID1	7.16e-08	195	172	9	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 SMOC1 MAP3K5 PIEZO2 LOXHD1 CLMP PID1	7.16e-08	195	172	9	44d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DRC7 CFAP47 MYO1H E2F7 E2F8 DNAH12 NGEF DNAH5 DNAH6	7.82e-08	197	172	9	6e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell	healthy_donor-Lymphocytic-ILC-NK_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TPST2 SYTL2 ARHGEF12 NCAM1 IL18R1 IGFBP7 SYNE2 B3GAT1 SORL1	8.16e-08	198	172	9	d7053a898e04478c577381085f615edaad3cdc5b
ToppCell	healthy_donor-Lymphocytic-ILC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TPST2 SYTL2 ARHGEF12 NCAM1 IL18R1 IGFBP7 SYNE2 B3GAT1 SORL1	8.16e-08	198	172	9	aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 FRAS1 SLC28A3 NBEA SH3BP4 HCAR3 B3GAT1 GALNT6 DNAH5	8.16e-08	198	172	9	fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SYT6 OBSCN XPNPEP2 KCNIP3 MAP3K5 SH3BP4 PDLIM1 RASAL1	2.32e-07	162	172	8	4d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCell	droplet-Lung-nan-3m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCAR2 ADAMTSL1 SYTL2 IL18R1 E2F8 EML5 ABTB1 GALNT6	3.20e-07	169	172	8	da607c1d068038d5a3d1117f6aa6e4c6f3552e97
ToppCell	droplet-Lung-nan-3m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCAR2 ADAMTSL1 SYTL2 IL18R1 E2F8 EML5 ABTB1 GALNT6	3.20e-07	169	172	8	a14b46231e079a0fd9f3ca13d5d48113be76fd0f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 IGFN1 ABCA13 OBSCN PIEZO2 LOXHD1 CSMD1 DNAH5	6.11e-07	184	172	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 IGFN1 ABCA13 OBSCN PIEZO2 LOXHD1 CSMD1 DNAH5	6.11e-07	184	172	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 IGFN1 ABCA13 OBSCN PIEZO2 LOXHD1 CSMD1 DNAH5	6.11e-07	184	172	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FRAS1 SYT6 SMOC1 HAPLN1 LINGO1 IGFBP7 CLMP PLOD2	7.19e-07	188	172	8	ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRG1 IGFN1 MYOM1 SYTL2 CCDC85A LINGO1 IGFBP7 PDLIM1	7.79e-07	190	172	8	a7f6c38bbf451f166febb21e6719d4afced4035e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 MAP3K5 PIEZO2 LOXHD1 CLMP PID1	9.11e-07	194	172	8	240d122dcb9dd1ab2867503ad85869853adcacae
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 MAP3K5 PIEZO2 LOXHD1 CLMP PID1	9.11e-07	194	172	8	ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	CFAP47 ARHGEF12 NBEA DNAH12 IGFBP7 SYNE2 DNAH5 DNAH6	9.47e-07	195	172	8	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	CFAP47 ARHGEF12 NBEA DNAH12 IGFBP7 SYNE2 DNAH5 DNAH6	9.47e-07	195	172	8	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 MAP3K5 PIEZO2 IGFBP7 CLMP PID1	9.84e-07	196	172	8	2b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	CFAP47 ABCA13 ARHGEF12 DNAH12 IGFBP7 SYNE2 DNAH5 DNAH6	9.84e-07	196	172	8	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	CFAP47 ABCA13 ARHGEF12 DNAH12 IGFBP7 SYNE2 DNAH5 DNAH6	9.84e-07	196	172	8	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FRAS1 PDE3B SYTL2 SESN3 FRYL ZDBF2 SYNE2 XRN1	1.02e-06	197	172	8	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 MAP3K5 PIEZO2 LOXHD1 CLMP PID1	1.02e-06	197	172	8	b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 MAP3K5 PIEZO2 LOXHD1 CLMP PID1	1.02e-06	197	172	8	6d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 MAP3K5 PIEZO2 LOXHD1 CLMP PID1	1.02e-06	197	172	8	c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell	10x3'2.3-week_17-19-Myeloid_neutrophil-granulo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HCAR2 ABCA13 FPR1 CAPG HCAR3 GYG1 SYNE2 SORL1	1.06e-06	198	172	8	f870e398e996c1f28c8462d87b18f71b20c71011
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CHL1 PAMR1 DIABLO ABCA13 LAMA5 IGFBP7 LRRC14 EIF3B	1.06e-06	198	172	8	399760b6b6fef8639ded53b14f251b9fce600e81
ToppCell	COVID-19-lung-Capillary_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PECAM1 LAMA5 IL18R1 CCDC85A PTPRB LINGO1 PDLIM1 CSMD1	1.06e-06	198	172	8	45419f2804b4be79bae6632e71c54e1af482d115
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 FRAS1 ABCA13 OBSCN LAMA5 CROT PDLIM1 CSMD1	1.10e-06	199	172	8	94a7867e800df352731796de8c24cba133c29622
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	HCAR2 ABCA13 FPR1 HCAR3 GYG1 SYNE2 ABTB1 SORL1	1.10e-06	199	172	8	5919933c4b842b98fc98685dc8c72c8dd32c6ea3
ToppCell	facs-Aorta-Heart-3m-Epithelial-epithelial_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRC7 MYOM1 MYO1H PPARGC1B TLL2 IGSF9B DNAH6	2.05e-06	151	172	7	0de76acd1b204345dce7f33be2a1ed9fbe9e6da0
ToppCell	facs-Aorta-Heart-3m-Epithelial-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRC7 MYOM1 MYO1H PPARGC1B TLL2 IGSF9B DNAH6	2.05e-06	151	172	7	20b9c8fb966c5d62ff909cc4a4616b109b78cdca
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Krt80_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYO1H SYT6 OBSCN KCNIP3 SH3BP4 PDLIM1 RASAL1	2.05e-06	151	172	7	f50c5ae9dae507df750df25e151b58685fec70ce
ToppCell	facs-Aorta-Heart-3m-Epithelial\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRC7 MYOM1 MYO1H PPARGC1B TLL2 IGSF9B DNAH6	2.05e-06	151	172	7	bee48137d1f5f27a24571a59c835284651d38538
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CHL1 NCAM1 ZC3H12B SMOC1 HAPLN1 LINGO1 IGSF9B	2.44e-06	155	172	7	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	severe_influenza-CD8+_T_naive\|World / disease group, cell group and cell class (v2)	MYOM1 OBSCN SESN3 ZDBF2 METTL21A EBP FAM216A	3.01e-06	160	172	7	a1181ef36b453eba53b04d836aa9f65a71354cdb
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DRC7 PDE3B PEX1 FRYL ARHGEF1 SYNE2 HERC2	3.14e-06	161	172	7	5fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SYT6 OBSCN KCNIP3 MAP3K5 SH3BP4 PDLIM1 RASAL1	3.27e-06	162	172	7	58da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCell	ASK428-Immune-Mast_cell\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	TPST2 CAPG NBEA IL18R1 PTPRB CD22 RASAL1	3.41e-06	163	172	7	569ca0e8ce307f258910b0c75c498009a9651e6e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 SYTL2 NBEA DNAH12 DNAH5 DNAH6 SEC14L4	4.32e-06	169	172	7	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D\|367C / Donor, Lineage, Cell class and subclass (all cells)	NUGGC MYO1H NCAM1 CDK5R1 SYNE2 B3GAT1 SORL1	4.85e-06	172	172	7	6379ae0aca9007c3a8a87e3330908fc90961ad3f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG1 LRRK1 CCDC85A LOXHD1 LINGO1 CLMP IGSF9B	6.08e-06	178	172	7	731e1e8eff2c4018c75dfc66632a316010a09a9a
ToppCell	COVID-19_Mild-NK_CD56bright\|COVID-19_Mild / Disease condition and Cell class	TPST2 CAPG NCAM1 IL18R1 SH3BP4 IGFBP7 FES	6.31e-06	179	172	7	90e7a4af195aa2332b07a9f06cde63e72ff49255
ToppCell	COVID-19_Severe-Neutrophil-\|COVID-19_Severe / Disease condition and Cell class	HCAR2 FPR1 IL18R1 HCAR3 SYNE2 ABTB1 SORL1	6.78e-06	181	172	7	5e5101195d5ff8c8ea7ddcf0bc4f4e03e64c01e0
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	PECAM1 ARHGEF12 LAMA5 CCDC85A PTPRB PDLIM1 SYNE2	6.78e-06	181	172	7	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell	COVID-19_Severe-Neutrophil\|COVID-19_Severe / Disease condition and Cell class	HCAR2 FPR1 IL18R1 HCAR3 SYNE2 ABTB1 SORL1	6.78e-06	181	172	7	aa5e5fb0308b5e2ef918548c85529c9a433c57f5
ToppCell	COVID-19-Epithelial-Ionocytes\|Epithelial / Condition, Lineage and Cell class	IBA57 NCAM1 URB2 SMOC1 ITPR2 B3GAT1 SORL1	6.78e-06	181	172	7	4a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCell	P28-Endothelial-unknown_endothelial_cell-endothelial_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TPST2 PECAM1 ARHGEF12 XPNPEP2 CCDC85A PIEZO2 IGFBP7	8.10e-06	186	172	7	a38f84f478798951c8798c8e90e4897c729cf630
ToppCell	P28-Endothelial-unknown_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TPST2 PECAM1 ARHGEF12 XPNPEP2 CCDC85A PIEZO2 IGFBP7	8.10e-06	186	172	7	dde38decf368775694bbeae38a3ff084017c34ab
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 MYH10 NCAM1 IGSF10 PIEZO2 GYG1 CLMP	8.99e-06	189	172	7	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 PIEZO2 LOXHD1 CLMP PID1	9.31e-06	190	172	7	2306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 SMOC1 KCNIP3 SH3BP4 IGSF9B CSMD1 PID1	9.31e-06	190	172	7	9b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 PIEZO2 LOXHD1 CLMP PID1	9.31e-06	190	172	7	1f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 SMOC1 KCNIP3 SH3BP4 IGSF9B CSMD1 PID1	9.31e-06	190	172	7	d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAMR1 NCAM1 SMOC1 MAP3K5 EML5 CLMP PID1	9.63e-06	191	172	7	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 PIEZO2 LOXHD1 CLMP PID1	9.63e-06	191	172	7	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	COPD-Myeloid-cDC2\|COPD / Disease state, Lineage and Cell class	MANBA FPR1 IL18R1 SH3BP4 CSMD1 PID1 RASAL1	9.63e-06	191	172	7	2af6e4a6bd1f2193ece2131c3b7d976dd23a6966
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAMR1 NCAM1 SMOC1 MAP3K5 EML5 CLMP PID1	9.63e-06	191	172	7	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	LPS_only-Endothelial-Epi-like-Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATCAY E2F7 NCAM1 CDK5R1 TLL2 WDR17	9.64e-06	126	172	6	e065304f480a5e38532b66508b0ee87cc48bba9b
ToppCell	LPS_only-Endothelial-Epi-like\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATCAY E2F7 NCAM1 CDK5R1 TLL2 WDR17	9.64e-06	126	172	6	4c598f7bae09aca7a4ecce63dfd6890b26468c73
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 PIEZO2 LOXHD1 CLMP PID1	9.96e-06	192	172	7	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 PDE3B SLF1 PECAM1 ARHGEF12 CCDC85A ZC3H12C	9.96e-06	192	172	7	c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 PIEZO2 LOXHD1 CLMP PID1	9.96e-06	192	172	7	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	TPST2 ADAMTSL1 PECAM1 SMOC1 IL18R1 PTPRB SYNE2	1.03e-05	193	172	7	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTSL1 PAMR1 IGSF10 PIEZO2 IGFBP7 CLMP PID1	1.03e-05	193	172	7	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	severe-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CHL1 LAMA5 ZDBF2 PDLIM1 CD22 PLOD2 RASAL1	1.07e-05	194	172	7	2fee6083fb56b16d1f04fd0b92ec622fd26ba3fa
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PAMR1 SYT6 SESN3 AR PIEZO2 GYG1 PID1	1.10e-05	195	172	7	70387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCell	COVID-19-Heart-EC_1\|Heart / Disease (COVID-19 only), tissue and cell type	PECAM1 LAMA5 FRYL CCDC85A CARD8 PTPRB SYNE2	1.10e-05	195	172	7	50a193475db1bb1e05b8590225a553688c372c14
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 MAP3K5 PIEZO2 CLMP PID1	1.10e-05	195	172	7	d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CHL1 ATCAY NCAM1 SMOC1 KCNIP3 LINGO1 IGSF9B	1.14e-05	196	172	7	f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 PIEZO2 LOXHD1 CLMP PID1	1.14e-05	196	172	7	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CHL1 ATCAY NCAM1 SMOC1 KCNIP3 LINGO1 IGSF9B	1.14e-05	196	172	7	671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 PIEZO2 LOXHD1 CLMP PID1	1.14e-05	196	172	7	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	COVID-19-lung-Capillary_Aerocytes\|lung / Disease (COVID-19 only), tissue and cell type	CHL1 PDE3B PECAM1 ARHGEF12 LAMA5 CCDC85A SYNE2	1.14e-05	196	172	7	4ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PAMR1 NCAM1 MAP3K5 IGFBP7 CLMP PID1	1.18e-05	197	172	7	80e153790cef37b743e22a7370ff5b3a6abf147d
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	HCAR2 PTPMT1 PECAM1 PDLIM1 CNIH4 SCD ALAS1	1.18e-05	197	172	7	07aee25e17dbb71e49f7da9fd9ed2537f4a72d82
ToppCell	10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HCAR2 ABCA13 FPR1 HCAR3 GYG1 SYNE2 SORL1	1.22e-05	198	172	7	82f6ac18c3a6487f03579b5c247844f1c115c2be
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 ABCA13 SYTL2 NBEA SH3BP4 GALNT6 SORL1	1.22e-05	198	172	7	af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCell	BL-critical-LOC-Epithelial\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CHL1 ABCA13 NBEA DNAH12 IGFBP7 PDLIM1 DNAH5	1.22e-05	198	172	7	6218a25b94d5fa2c69880539adf9c63bfe52dcd3
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-neutrophil-neutrophil\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	HCAR2 FPR1 HCAR3 GYG1 SYNE2 ABTB1 SORL1	1.22e-05	198	172	7	e76061e66f6d60f5735962aa7777dda8958caed9
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 ATCAY L1CAM NCAM1 NBEA CDK5R1 EML5	1.22e-05	198	172	7	800ade4261695f2efd869d2b1243571de963c431
ToppCell	COVID-19-lung-Capillary_2\|lung / Disease (COVID-19 only), tissue and cell type	PECAM1 LAMA5 IL18R1 PTPRB LINGO1 SYNE2 CSMD1	1.26e-05	199	172	7	793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-neutrophil\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	HCAR2 ABCA13 FPR1 GYG1 SYNE2 ABTB1 SORL1	1.26e-05	199	172	7	caf2e050b21e7a16ce4e51b3f135debd06810231
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 FRAS1 SLC28A3 NBEA SH3BP4 B3GAT1 GALNT6	1.30e-05	200	172	7	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	Biopsy_Control_(H.)-Epithelial-Differentiating_Ciliated\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	DRC7 CFAP47 ABCA13 E2F7 DNAH12 DNAH5 DNAH6	1.30e-05	200	172	7	a552a99f5e4fa00dfb7775e5a3e1f62f1530d104
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	CHL1 KDM5B PDE3B ATCAY NCAM1 SYNE2 PID1	1.30e-05	200	172	7	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	PDE3B OBSCN KCNIP3 EML5 SCD SYDE2 GALNT6	1.30e-05	200	172	7	be83f442179ba4217d12f0458059586ff3130991
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYOM1 SYTL2 NCAM1 LINGO1 IGFBP7 CSMD1 CAP2	1.30e-05	200	172	7	a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCell	wk_15-18-Mesenchymal-Fibroblast-intermediate_fibro\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PAMR1 AR IGSF10 PIEZO2 GYG1 CLMP PID1	1.30e-05	200	172	7	6461d25fd8fb52921b188f083fbe808535d3130b
ToppCell	368C-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	E2F7 E2F8 RIF1 NLRP14 MARF1 ZC3H12C	2.59e-05	150	172	6	c3ad5fa41eb636a5d691c0268c0f1c32cd0de658
ToppCell	368C-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	E2F7 E2F8 RIF1 NLRP14 MARF1 ZC3H12C	2.59e-05	150	172	6	78b8029e71d26f336a46274c8afef3435bf536b9
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MANBA SESN3 ARHGEF12 SLC28A3 AR RASAL1	3.35e-05	157	172	6	6a0aa66964eecbbc232abf1d2e6c8422e4ce69d0
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_IT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	IGFN1 HTRA4 LINGO1 IGFBP7 PDLIM1 TLL2	3.47e-05	158	172	6	9e0589f770920f8ac41cfe5cd0a29e9e7a04a308
ToppCell	control-NK_CD56bright\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TPST2 FRAS1 NCAM1 TOGARAM1 IL18R1 IGFBP7	3.73e-05	160	172	6	f49c810072604c4dee51025073c9e088c00daf4a
Disease	alcohol consumption measurement	MPP3 GABRG1 MYH10 ARPC1A FAM114A2 ENTHD1 NCAM1 SLC28A3 NBEA ARPC1B PTPRB LINGO1 IGFBP7 XRN1 MICAL3 IGSF9B EXOG CSMD1 DNAH5 CUX1 SORL1	7.80e-06	1242	167	21	EFO_0007878
Disease	FEV/FEC ratio	FRAS1 ITCH NOG FPR1 UTP14A NCAM1 IL18R1 HAPLN1 MINDY3 PPARGC1B DNAH12 SYNE2 MAIP1 MICAL3 CSMD1 TAF7 DNAH5 CUX1 SORL1	7.18e-05	1228	167	19	EFO_0004713
Disease	triacylglycerol 56:9 measurement	CCDC85A MAGEC1 MAGEC2	1.14e-04	17	167	3	EFO_0010436
Disease	Malignant neoplasm of breast	MICAL1 OBSCN NUP98 KCNIP3 AR RIF1 PPARGC1B ZNF22 NLRP14 IGFBP7 RRP9 SYNE2 AP1M1 HERC2 MAGEC2 CUX1 SORL1	1.34e-04	1074	167	17	C0006142
Disease	blood manganese measurement	SMOC1 CSMD1 PID1	4.71e-04	27	167	3	EFO_0007581
Disease	unipolar depression	MICAL1 ADAMTSL1 NRDC ABCA13 MYO1H NCAM1 METTL21EP MAP3K5 HAPLN1 SH3BP4 ITPR2 PIEZO2 LINGO1 CNIH4 SYNE2 CSMD1 DNAH6	5.13e-04	1206	167	17	EFO_0003761
Disease	peak expiratory flow	MICAL1 NOG NRDC ZC3H12B HAPLN1 SLC9A3 LINGO1 XRN1 MICAL3 SORL1	5.73e-04	498	167	10	EFO_0009718
Disease	MASA syndrome (implicated_via_orthology)	CHL1 L1CAM	6.56e-04	7	167	2	DOID:0060246 (implicated_via_orthology)
Disease	insulinoma (is_marker_for)	NCAM1 CUX1	8.72e-04	8	167	2	DOID:3892 (is_marker_for)
Disease	hypothyroidism (biomarker_via_orthology)	L1CAM NCAM1 CDK5R1 PLOD2	1.12e-03	80	167	4	DOID:1459 (biomarker_via_orthology)
Disease	tuberculosis	AHCYL2 SMOC1 IGFBP7 MAGEC1 CSMD1 MAGEC2	1.49e-03	216	167	6	MONDO_0018076
Disease	Liver Cirrhosis, Experimental	PAMR1 INHBC CAPG NBEA XPNPEP2 SMOC1 ARPC1B DUS1L MINDY3 CROT IGFBP7 PLOD2	1.58e-03	774	167	12	C0023893
Disease	nevus count, cutaneous melanoma	TASOR2 PPARGC1B SYNE2 HERC2	1.80e-03	91	167	4	EFO_0000389, EFO_0004632
Disease	schizophrenia (is_marker_for)	ARPC1A NCAM1 ARPC1B	1.99e-03	44	167	3	DOID:5419 (is_marker_for)
Disease	coffee consumption measurement, tea consumption measurement	NCAM1 LINGO1 XRN1	1.99e-03	44	167	3	EFO_0006781, EFO_0010091
Disease	ADHD symptom measurement	ARHGEF12 CUX1	2.02e-03	12	167	2	EFO_0007860
Disease	illegal drug consumption	SYT6 CSMD1	2.38e-03	13	167	2	EFO_0005431
Disease	refractive error	ADAMTSL1 NOG ENTHD1 NBEA ITPR2 IGFBP7 ABTB1	2.65e-03	326	167	7	MONDO_0004892
Disease	C-X-C motif chemokine 11 measurement	NAAA CUX1	2.77e-03	14	167	2	EFO_0008057
Disease	lung non-small cell carcinoma (is_marker_for)	DIABLO PECAM1 L1CAM PTPRB CUX1	2.81e-03	169	167	5	DOID:3908 (is_marker_for)
Disease	Psoriasis	HCAR2 ZC3H12C CSMD1	4.16e-03	57	167	3	C0033860
Disease	Pustulosis of Palms and Soles	HCAR2 ZC3H12C CSMD1	4.16e-03	57	167	3	C0030246
Disease	neuroblastoma	LAMA5 CSMD1 DNAH5 CAP2	4.33e-03	116	167	4	EFO_0000621
Disease	cutaneous melanoma	TASOR2 PPARGC1B SYNE2 HERC2	5.03e-03	121	167	4	EFO_0000389
Disease	response to methotrexate, juvenile idiopathic arthritis	ENTHD1 CSMD1	5.11e-03	19	167	2	EFO_0002609, GO_0031427
Disease	bipolar disorder, schizophrenia, response to lithium ion	MYO1H MAIP1	5.66e-03	20	167	2	GO_0010226, MONDO_0004985, MONDO_0005090

Protein segments in the cluster

Peptide	Gene	Start	Entry
SLLPGVKTQHWKKIE	URB2	646	Q14146
KILVWHTRTEKPVLV	B3GAT1	306	Q9P2W7
CTRVLVWHTRTEKPK	B3GAT3	301	O94766
KKLVHEGPLTWRVTK	ARHGEF1	646	Q92888
PQAIIIWDILTGHKK	EIF3B	401	P55884
LKRHSIISVLPWKRI	CDK5R1	41	Q15078
WIIEAKPGHSIKITF	CSMD1	786	Q96PZ7
VSDLLARPKPWHKLS	CUX1	1161	P39880
HIKKPIRSTVLSLDW	ARPC1B	136	O15143
LLWSEKIKGPLHIRA	IBA57	321	Q5T440
THVKPLIWIESVIEK	AP1M1	271	Q9BXS5
WEHIKAVRKAVAIPV	DUS1L	191	Q6P1R4
TLGSHWIRKEPKNLL	ABCA13	806	Q86UQ4
SELIRPWHKTVTIGF	DIABLO	36	Q9NR28
KVTLHIKWPKSVEVE	DHX30	86	Q7L2E3
IHEGPLVWKVNRDKT	ARHGEF12	1021	Q9NZN5
HIKKPIRSTVLSLDW	ARPC1A	136	Q92747
TIKKTRFPHWDEVLE	RASAL1	171	O95294
ARLWTEIPTKITIHE	ITPR2	801	Q14571
LSQETLPLKIHGWKS	ENTHD1	221	Q8IYW4
KFPIWIVGSETHLTV	MINDY3	276	Q9H8M7
HKGTIKESRVLAPWI	PTPRB	326	P23467
TQKLRVPAKWIHEAK	NUP98	1606	P52948
TPEGKWHASKVLRIE	IL18R1	271	Q13478
VPWKEAVRIHALLKG	MICAL3	961	Q7RTP6
VLTKKPDHGHVLWRQ	FRAS1	1996	Q86XX4
KDKTWTRIPTEHLLR	LZTR1	261	Q8N653
WGPRAHSEVIKRKVV	MAGEC1	1071	O60732
WGPRAHSESIKKKVL	MAGEC2	301	Q9UBF1
KPDWTIARIEHSKLL	MAIP1	276	Q8WWC4
LSSHWRPKDVVVVAL	LPAR2	21	Q9HBW0
VKVTWSTVPKDRVHG	CHL1	826	O00533
LVTWKQVGLELKPHS	ALAS1	591	P13196
PGKTALRVKWSHLRL	LRRK1	251	Q38SD2
RVPKWVHVLIGKVVL	NAAA	71	Q02083
LWGITIGLTVHLLKK	HCAR2	151	Q8TDS4
LPHRVWKVKFVGESV	HERC2	4461	O95714
WTLKVRVLVLGPHNT	INHBC	146	P55103
LRKNLKSLIIVHPSW	ATCAY	261	Q86WG3
KSLIIVHPSWFIRTV	ATCAY	266	Q86WG3
IPKRELAWHVKTITI	LOXHD1	1886	Q8IVV2
KPLITWEKDGQHLIS	ADAMTSL1	906	Q8N6G6
HAPVLELEGKKWRVE	CAP2	321	P40123
TEKPVIELWKKHTLA	PID1	111	Q7Z2X4
PAKVRDLHLKWTEGI	PDE3B	941	Q13370
TVRVILAPWKKGLIA	PECAM1	591	P16284
PHSVKEQAKILWRRG	FAM169B	36	Q8N8A8
TLADGWPKNLKIILH	FRYL	1391	O94915
KTDQPTRHWIKRGVA	DNAH12	3071	Q6ZR08
VKWRPVDLAQVKGHL	L1CAM	831	P32004
ILWLSPRKHLVSAKS	LINGO1	456	Q96FE5
KVALLLGVEIHWGVT	MICAL1	166	Q8TDZ2
QAKRVPRWVLEHISK	EXOG	86	Q9Y2C4
PRWVLEHISKSKIMG	EXOG	91	Q9Y2C4
WELQGSTLKIPHVER	KDM5B	111	Q9UGL1
KHLPQVKELSWGVAL	METTL21EP	166	A6NDL7
RQLVHVVKWAKALPG	AR	711	P10275
HSELTVTVRVPKGRW	LAMA5	1356	O15230
IPTPVLIWNKVKRGH	IGFBP7	186	Q16270
KHEVTGWVLVSPLSK	IGFBP7	226	Q16270
WVVSKFGRVLPVLHL	NOL8	141	Q76FK4
RKIIAPLVTRHGKLW	PLOD2	411	O00469
HPAATVTWRKGLLEL	OBSCN	2941	Q5VST9
PPHIQTKTVVKELTW	METTL21A	111	Q8WXB1
HKWSPEEAVRAIAKI	PTPMT1	151	Q8WUK0
IEKVGKENWLPRSHT	ITCH	856	Q96J02
KLRTDWVVAGHPSQV	DNAH6	1306	Q9C0G6
KVAPSVVHVQLWGRL	HTRA4	176	P83105
HWTRVPSGLDLSKRK	IGSF10	1681	Q6WRI0
ASAKVVHFLGRVKPW	GYG1	206	P46976
VHVTEERGRKPAFKW	E2F7	351	Q96AV8
VHVTEERGRKPAFKW	E2F8	331	A0AVK6
KTWVLAPKIHEGDIT	GABRG1	51	Q8N1C3
PWLKSLVSRKDHVLD	GALNT6	41	Q8NCL4
KRHGTLVWDTEVKPV	CARD8	421	Q9Y2G2
KWKELGHDLHSISIP	CEP350	2936	Q5VT06
TLQHWPHIIRIGDLK	DENND6A	361	Q8IWF6
HVIDRWLGEPIKAAI	PRMT5	216	O14744
PEPVVHSLKVVWRKL	CCDC85A	516	Q96PX6
HISRDKITRPGAKLW	DNAJB11	286	Q9UBS4
VHSWVLVLSGKREVP	DRC7	301	Q8IY82
AHEWIRKSLTKPLAE	FAM114A2	336	Q9NRY5
KRLKSHPSIIIWSGN	MANBA	441	O00462
PQVVWIKGHGHKRIV	MARF1	1541	Q9Y4F3
DWAPRQTHKVIPLKG	GAMT	101	Q14353
QTHKVIPLKGLWEDV	GAMT	106	Q14353
VQDPGLHVWRVEKLK	CAPG	16	P40121
LHVWRVEKLKPVPVA	CAPG	21	P40121
RKSHIPGVSIWQLVE	IGFN1	6	Q86VF2
WDTETIKPLSILKGH	EML5	756	Q05BV3
WLVLPGVLVLDAVKH	EBP	196	Q15125
HSLWRPVRNKEGIKT	FAM216A	196	Q8WUB2
SILLRGTVHEKLKWA	KCNIP3	156	Q9Y2W7
SELKLAVPWGHIAAK	SERHL2	11	Q9H4I8
EGLSLKHLWKPAVEV	SEC14L4	156	Q9UDX3
HVRPWKRGILKGTIT	CFAP47	2471	Q6ZTR5
TKNVEVLHLGKVWIP	PEX1	401	O43933
VLHLGKVWIPDDLRK	PEX1	406	O43933
TAKKLVWIPSERHGF	MYH10	31	P35580
RTEEKVHIPKILPWH	CD22	376	P20273
VGPRAELEHWKKRLS	DNAH5	281	Q8TE73
WQLLRKEKVPVHKVG	CROT	136	Q9UKG9
EWTIHAKPGFVIQLR	PAMR1	151	Q6UXH9
HKVWSPLVTEEGKRH	PDLIM1	86	O00151
GSGIHKIRIKWTKLT	HAPLN1	71	P10915
VCKPSKSVHLTVLRW	NOG	191	Q13253
KVVLEKLSKDTHWVP	MPP3	566	Q13368
SGVVLHRAVPKDKWV	FES	541	P07332
ISIWHVLPDDKKGIH	MAP3K5	586	Q99683
GAEEPKLKWEHITTL	MAP3K5	1076	Q99683
SELKLAVPWGHIAAK	SERHL	11	Q9NQF3
VSRLTGEAEKWAIPH	RTL6	141	Q6ICC9
HLKLVVFSWEPTPRK	SYDE2	741	Q5VT97
PRKPIAHWHSLVEVK	SYT6	486	Q5T7P8
KKLPTTGEVHIWVKE	SYTL2	786	Q9HCH5
IWNHGITLPLKNVRK	TAF7	131	Q15545
VHTGKTSVVIKWESP	SORL1	1941	Q92673
WPLIKHVEVTLPKSD	NUGGC	266	Q68CJ6
PKSGTHWRDIRNIIK	SERAC1	21	Q96JX3
HVIWPDGKRIVLLAE	AHCYL2	506	Q96HN2
AKHWEPFRKVVSGRI	TMCO4	441	Q5TGY1
NPITKRWKHLTGTLI	SH3BP4	926	Q9P0V3
PKAHVKELISWLVGQ	SYNE2	1906	Q8WXH0
PLAKWHRSKEGLTER	KARS1	471	Q15046
AVRWAKLVIPLVVHS	RIF1	181	Q5UIP0
HRTVSLAKKVIIGPW	FPR1	136	P21462
LWGITVGLTVHLLKK	HCAR3	151	P49019
SGIWPRHAVKLLSVL	NBEA	206	Q8NFP9
IKPLVQWLKVKRSEH	SLC9A3	456	P48764
VPIISHSRWLLKQGE	NGEF	481	Q8N5V2
RKVLRSWEPSGVHLE	PPARGC1B	706	Q86YN6
LIAKKIHPQTIIAGW	CCT2	116	P78371
IHPQTIIAGWREATK	CCT2	121	P78371
IKQGWHPILEKISAE	MSH4	646	O15457
TAKVFHVKWSPLREG	WDR17	566	Q8IZU2
ETLSEWIKHRPQKVG	WIZ	1436	O95785
KHKTTLRHIIWGILL	SLC28A3	96	Q9HAS3
DKWQPLLSTVTGVHK	HERC2P3	331	Q9BVR0
IKAAESHWGLPVQKL	SLX4IP	226	Q5VYV7
TKWKGKSVVVLRHPL	ABTB1	146	Q969K4
WSHVILKVLVRPSKP	CLMP	121	Q9H6B4
KWVIPELIGHTIVTV	CNIH4	46	Q9P003
PPTIIWKHKGRDVIL	NCAM1	146	P13591
PGWKAVLTILLAHKQ	ZC3HC1	456	Q86WB0
KIWDILGDRPSLVHS	PWP1	411	Q13610
PVRWVTGLLKELHVR	URGCP	671	Q8TCY9
ASIRIPWTKLKTHPI	UHRF1BP1L	66	A0JNW5
SRSKPHVIALLEQWK	ZNF30	56	P17039
KPVNLEALSKWTGHI	TPST2	291	O60704
ITAPTLWIKHLVIKD	SMOC1	196	Q9H4F8
AVRKEPIETLRIKHW	TXNDC16	786	Q9P2K2
VIGPRKKFHWDDTIR	UBN2	596	Q6ZU65
VHVTKEGVWKNPVLL	RLF	176	Q13129
LPREVLHKWSPKQIG	SLC25A46	186	Q96AG3
IKWSVESGRKLHVIP	RRP9	171	O43818
VITWRKVGKPSRSKH	IGSF9B	451	Q9UPX0
PWLITKEHIQKLVKT	SESN3	166	P58005
WKGRLQVTEHLPEKI	TIMMDC1	236	Q9NPL8
GALPVKLRTWVESQH	ZNF274	211	Q96GC6
GIDPTVKERLWLTLH	GEMIN5	276	Q8TEQ6
LPVHTEISWKADGKI	GEMIN5	536	Q8TEQ6
WITDPKTALRQRHKE	PIEZO2	1586	Q9H5I5
KVQEIITWLKGHPVS	XRN1	1026	Q8IZH2
AATHKPEVIVKETWL	ZDBF2	966	Q9HCK1
HCVWRISVTPGEKIV	TLL2	376	Q9Y6L7
VVPIRKIHALTITWA	NRDC	431	O43847
HVGWLLVRKHPAVKE	SCD	181	O00767
IEHVLSGWKARTPLE	UTP14A	171	Q9BVJ6
PGAFHRWKVVLLVRT	SLF1	121	Q9BQI6
GHKDITVFVPAWRKE	ZC3H12B	226	Q5HYM0
WVKLRHPKAATERVA	ZFP69B	16	Q9UJL9
NWSHPKSVIVGLIKE	UEVLD	116	Q8IX04
NIRVKTHLPSWKAGT	ZNF22	201	P17026
LEKTVVRALHGPWNT	TASOR2	766	Q5VWN6
TPHRGRLWIAATAKK	TRIP4	461	Q15650
LHKEVGTTPIVTWLL	XPNPEP2	131	O43895
GHKDITVFVPAWRKE	ZC3H12C	281	Q9C0D7
RKPHATEQKVLVVLW	TOGARAM1	1641	Q9Y4F4
ASIRIQWTKLKTHPI	UHRF1BP1	66	Q6BDS2
VTLLIWVPVKVILHK	TMEM236	61	Q5W0B7
DKKTVVLRELVHTWP	LRRC14	41	Q15048
EHGLTPWNEVKKARR	NLRP14	41	Q86W24
KWIAKLLGVHPSVLL	MYO1H	301	Q8N1T3
RKDSLVLQWKPPVHS	MYOM1	1051	P52179