Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18 FBXO38	1.58e-05	82	130	6	GO:1990756
GeneOntologyMolecularFunction	nuclear retinoic acid receptor binding	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	2.90e-05	55	130	5	GO:0042974
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18 FBXO38	3.67e-05	95	130	6	GO:0140767
GeneOntologyMolecularFunction	ATP-dependent activity	ACSL6 ATP6V1E1 SRPRA FANCM TRIP13 ABCA7 KIF9 MDN1 DNAH17 DDX53 MORC3 CDC6 SLC27A4 KIF22	4.80e-05	614	130	14	GO:0140657
GeneOntologyMolecularFunction	6-phosphofructo-2-kinase activity	PFKFB1 PFKFB3	2.50e-04	4	130	2	GO:0003873
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18 FAF1 TCERG1 TAF1 SPEN TP73	4.07e-04	417	130	10	GO:0061629
GeneOntologyMolecularFunction	testosterone 6-beta-hydroxylase activity	CYP3A7 CYP3A4	4.15e-04	5	130	2	GO:0050649
GeneOntologyMolecularFunction	fructose-2,6-bisphosphate 2-phosphatase activity	PFKFB1 PFKFB3	4.15e-04	5	130	2	GO:0004331
GeneOntologyMolecularFunction	ATP hydrolysis activity	SRPRA FANCM TRIP13 ABCA7 KIF9 MDN1 DDX53 MORC3 CDC6 KIF22	6.29e-04	441	130	10	GO:0016887
GeneOntologyMolecularFunction	phosphofructokinase activity	PFKFB1 PFKFB3	8.65e-04	7	130	2	GO:0008443
GeneOntologyMolecularFunction	estrogen 2-hydroxylase activity	CYP3A7 CYP3A4	1.15e-03	8	130	2	GO:0101021
GeneOntologyMolecularFunction	nuclear receptor binding	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18 TAF1	1.42e-03	187	130	6	GO:0016922
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 DGKQ PRAMEF18 FAF1 TCERG1 TAF1 SPEN TP73	1.49e-03	582	130	11	GO:0140297
GeneOntologyMolecularFunction	sugar-phosphatase activity	PFKFB1 PFKFB3	1.83e-03	10	130	2	GO:0050308
GeneOntologyMolecularFunction	complement component C1q complex binding	C4A C4B	1.83e-03	10	130	2	GO:0001849
GeneOntologyMolecularFunction	promoter-specific chromatin binding	RBL1 PDX1 TP63 TAF1	2.12e-03	83	130	4	GO:1990841
GeneOntologyMolecularFunction	carbohydrate phosphatase activity	PFKFB1 PFKFB3	2.23e-03	11	130	2	GO:0019203
GeneOntologyMolecularFunction	estrogen 16-alpha-hydroxylase activity	CYP3A7 CYP3A4	2.23e-03	11	130	2	GO:0101020
GeneOntologyMolecularFunction	arachidonate-CoA ligase activity	ACSL6 SLC27A4	2.23e-03	11	130	2	GO:0047676
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	CYP3A4 SQLE AKR1D1	2.23e-03	40	130	3	GO:0016709
GeneOntologyBiologicalProcess	positive regulation of apoptotic cell clearance	ABCA7 C4A C4B	1.25e-05	8	127	3	GO:2000427
GeneOntologyBiologicalProcess	regulation of apoptotic cell clearance	ABCA7 C4A C4B	2.65e-05	10	127	3	GO:2000425
GeneOntologyCellularComponent	Cul2-RING ubiquitin ligase complex	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	1.03e-05	47	129	5	GO:0031462
GeneOntologyCellularComponent	ubiquitin ligase complex	PRAMEF33 PRAMEF10 UBE2L6 PRAMEF22 PRAMEF19 PRAMEF18 FBXO38 LMO7 GAN TOPORS USP33	1.20e-05	352	129	11	GO:0000151
GeneOntologyCellularComponent	motile cilium	TCTE1 PRAMEF10 TCP11X2 PRAMEF22 PRAMEF19 PRAMEF18 KIF9 DNAH17 PKD1 CFAP57	7.23e-05	355	129	10	GO:0031514
GeneOntologyCellularComponent	cullin-RING ubiquitin ligase complex	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18 FBXO38 GAN	3.51e-04	212	129	7	GO:0031461
GeneOntologyCellularComponent	cilium	TCTE1 PRAMEF10 EFCAB6 TCP11X2 PRAMEF22 PRAMEF19 PRAMEF18 MKS1 KIF9 RAB34 DNAH17 PKD1 CEP83 CFAP57 TOPORS	4.33e-04	898	129	15	GO:0005929
MousePheno	abnormal amino acid metabolism	ACSL6 GCDH ADSL MOCOS	2.53e-06	14	102	4	MP:0013242
MousePheno	abnormal spermatogonia proliferation	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	2.25e-05	47	102	5	MP:0002685
MousePheno	increased kidney weight	PRAMEF33 GAK PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18 PKD1	9.07e-05	145	102	7	MP:0003917
MousePheno	abnormal duodenum morphology	PRAMEF10 PRAMEF22 PRAMEF19 PDX1 PRAMEF18	1.02e-04	64	102	5	MP:0003271
MousePheno	abnormal kidney weight	PRAMEF33 GAK PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18 PKD1 MOCOS	1.39e-04	208	102	8	MP:0002707
MousePheno	abnormal circulating amylase level	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRRT2 PRAMEF18 USP54	1.43e-04	156	102	7	MP:0008804
Domain	PRAME_family	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	7.53e-06	19	128	4	IPR026271
Domain	P53	TP63 TP73	1.39e-04	3	128	2	PF00870
Domain	P53	TP63 TP73	1.39e-04	3	128	2	PS00348
Domain	p53_DNA-bd	TP63 TP73	1.39e-04	3	128	2	IPR011615
Domain	p53_tetrameristn	TP63 TP73	1.39e-04	3	128	2	IPR010991
Domain	p53_tumour_suppressor	TP63 TP73	1.39e-04	3	128	2	IPR002117
Domain	-	TP63 TP73	1.39e-04	3	128	2	4.10.170.10
Domain	P53_tetramer	TP63 TP73	1.39e-04	3	128	2	PF07710
Domain	RetinoicA-induced_16-like	FHIP2A FHIP2B	2.77e-04	4	128	2	IPR019384
Domain	RAI16-like	FHIP2A FHIP2B	2.77e-04	4	128	2	PF10257
Domain	6Phosfructo_kin	PFKFB1 PFKFB3	2.77e-04	4	128	2	IPR013079
Domain	6Pfruct_kin	PFKFB1 PFKFB3	2.77e-04	4	128	2	IPR003094
Domain	6PF2K	PFKFB1 PFKFB3	2.77e-04	4	128	2	PF01591
Domain	Anaphylatoxin_comp_syst	C4A C4B	4.60e-04	5	128	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	4.60e-04	5	128	2	IPR001840
Domain	Cyt_P450_E_grp-II	CYP3A7 CYP3A4	4.60e-04	5	128	2	IPR002402
Domain	p53/RUNT-type_TF_DNA-bd	TP63 TP73	6.87e-04	6	128	2	IPR012346
Domain	Cyt_P450_E_CYP3A	CYP3A7 CYP3A4	6.87e-04	6	128	2	IPR008072
Domain	-	TP63 TP73	6.87e-04	6	128	2	2.60.40.720
Domain	ANATO	C4A C4B	9.57e-04	7	128	2	SM00104
Domain	PKD	PKD1 SORCS2	9.57e-04	7	128	2	PF00801
Domain	ANAPHYLATOXIN_2	C4A C4B	9.57e-04	7	128	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	9.57e-04	7	128	2	PS01177
Domain	ANATO	C4A C4B	9.57e-04	7	128	2	PF01821
Domain	Anaphylatoxin/fibulin	C4A C4B	9.57e-04	7	128	2	IPR000020
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	1.27e-03	8	128	2	IPR019565
Domain	Thiol-ester_cl	C4A C4B	1.27e-03	8	128	2	PF10569
Domain	MacrogloblnA2_CS	C4A C4B	1.27e-03	8	128	2	IPR019742
Domain	RuvA_2-like	FANCM KIF22	1.63e-03	9	128	2	IPR010994
Domain	PG/BPGM_mutase_AS	PFKFB1 PFKFB3	1.63e-03	9	128	2	IPR001345
Domain	PKD/Chitinase_dom	PKD1 SORCS2	1.63e-03	9	128	2	IPR022409
Domain	PKD	PKD1 SORCS2	1.63e-03	9	128	2	SM00089
Domain	-	TCTE1 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18 IGSF10 FBXO38 PKD1	1.68e-03	321	128	8	3.80.10.10
Domain	L_dom-like	TCTE1 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18 IGSF10 FBXO38 PKD1	1.92e-03	328	128	8	IPR032675
Domain	A2M	C4A C4B	2.02e-03	10	128	2	PF00207
Domain	A2M_N_2	C4A C4B	2.02e-03	10	128	2	IPR011625
Domain	A2M_comp	C4A C4B	2.02e-03	10	128	2	IPR011626
Domain	A2M_recep	C4A C4B	2.02e-03	10	128	2	PF07677
Domain	A2M_comp	C4A C4B	2.02e-03	10	128	2	PF07678
Domain	A2M_N	C4A C4B	2.02e-03	10	128	2	PF01835
Domain	A2M_N	C4A C4B	2.02e-03	10	128	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	2.02e-03	10	128	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	2.02e-03	10	128	2	PS00477
Domain	PGAM	PFKFB1 PFKFB3	2.02e-03	10	128	2	SM00855
Domain	A2M_N_2	C4A C4B	2.02e-03	10	128	2	PF07703
Domain	Macroglobln_a2	C4A C4B	2.02e-03	10	128	2	IPR001599
Domain	PG_MUTASE	PFKFB1 PFKFB3	2.02e-03	10	128	2	PS00175
Domain	P-loop_NTPase	SRPRA RHOT2 PFKFB1 SLFN5 PFKFB3 FANCM TRIP13 ABCA7 KIF9 MDN1 RAB34 DDX53 CDC6 KIF22	2.03e-03	848	128	14	IPR027417
Domain	PKD	PKD1 SORCS2	2.46e-03	11	128	2	PS50093
Domain	PKD_dom	PKD1 SORCS2	2.46e-03	11	128	2	IPR000601
Domain	-	PKD1 SORCS2	2.46e-03	11	128	2	2.60.40.670
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	1.17e-08	20	134	5	26694250
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	1.97e-08	22	134	5	31729367
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	3.93e-08	25	134	5	37451217
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	7.21e-08	28	134	5	25089626
Pubmed	Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	1.04e-07	30	134	5	38786026
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	2.33e-07	35	134	5	19389355
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	4.82e-07	17	134	4	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	4.82e-07	17	134	4	37781892
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	BICD2 TSPYL2 CDC42BPB CCDC85A FAF1 RNF123 DST TCERG1 LMO7 HECTD2 SCG2 PKD1 PNMA2 TAF1 USP54 MORC3 CAPRIN1 TRIM37 USP33	5.31e-07	1285	134	19	35914814
Pubmed	Duplication and positive selection among hominin-specific PRAME genes.	PRAMEF22 PRAMEF19 PRAMEF18	5.56e-07	5	134	3	16159394
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	6.18e-07	18	134	4	23894331
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	6.18e-07	18	134	4	12890732
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	6.18e-07	18	134	4	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	6.18e-07	18	134	4	14675769
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	6.18e-07	18	134	4	39181896
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	7.81e-07	19	134	4	28604677
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	9.73e-07	20	134	4	16580637
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	9.73e-07	20	134	4	21425410
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	PRAMEF10 PRAMEF22 PRAMEF19 ASCC1 PRAMEF18 PRPF18 RBM25 RAVER2 EIF3B SPEN	1.05e-06	347	134	10	16033648
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	1.45e-06	50	134	5	31806660
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	1.76e-06	23	134	4	19480014
Pubmed	p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes.	TRIP13 TP63 TP73	1.94e-06	7	134	3	28617799
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	2.50e-06	25	134	4	12620990
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	2.95e-06	26	134	4	18500982
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	YBEY UNC93A SRPRA SLFN5 ARHGEF17 ITPR2 IGSF10 RNF123 DST MDN1 PKD1 CFAP57 PLS1	5.82e-06	736	134	13	29676528
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	TCTE1 ZC3H14 PRAMEF33 PRAMEF10 CCDC137 CYP3A4 PRAMEF22 PRAMEF19 SQLE RHOT2 PRRT2 PRAMEF18 MKS1 MDN1 DNAH17 CDC6 USP33	6.18e-06	1242	134	17	30973865
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	YBEY RBL1 AHCTF1 TSPYL2 ASCC1 GCDH RHOT2 TRIP13 ABCA7 LUZP1 RBM25 PNMA2 TAF1 USP54 TOPORS TP73	6.66e-06	1116	134	16	31753913
Pubmed	LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	6.97e-06	32	134	4	37889087
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	KRT3 ZC3H14 PLOD3 AHCTF1 ASCC1 SRPRA LUZP1 ITPR2 RBM25 DST TCERG1 LMO7 GAN EIF3B TOPORS SPEN CAPRIN1	7.23e-06	1257	134	17	36526897
Pubmed	USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.	PRAMEF10 PRAMEF22 PRAMEF19 TSPYL2 PDX1 UNC93A PRAMEF18 MYPN GPC4 SORCS2 TAF1 PNOC	1.25e-05	674	134	12	37196079
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	1.47e-05	2	134	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	1.47e-05	2	134	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	1.47e-05	2	134	2	15998580
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	1.47e-05	2	134	2	7373044
Pubmed	Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7.	CYP3A7 CYP3A4	1.47e-05	2	134	2	28986474
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	1.47e-05	2	134	2	19062096
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	1.47e-05	2	134	2	3696167
Pubmed	FAM160B1 deficit associated with microcephaly, severe intellectual disability, ataxia, behavioral abnormalities and speech problems.	FHIP2A FHIP2B	1.47e-05	2	134	2	31353455
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	1.47e-05	2	134	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	1.47e-05	2	134	2	16098595
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	1.47e-05	2	134	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	1.47e-05	2	134	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	1.47e-05	2	134	2	17645767
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	1.47e-05	2	134	2	15787745
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	1.47e-05	2	134	2	12207352
Pubmed	p63 and p73 expression in extrahepatic bile duct carcinoma and their clinical significance.	TP63 TP73	1.47e-05	2	134	2	17385050
Pubmed	p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis.	TP63 TP73	1.47e-05	2	134	2	16413471
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	1.47e-05	2	134	2	30026462
Pubmed	The role of p53 protein family in gastrointestinal malignancies.	TP63 TP73	1.47e-05	2	134	2	16557273
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	1.47e-05	2	134	2	6559257
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	1.47e-05	2	134	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	1.47e-05	2	134	2	22387014
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	1.47e-05	2	134	2	34299197
Pubmed	Tumor-specific p73 up-regulation mediates p63 dependence in squamous cell carcinoma.	TP63 TP73	1.47e-05	2	134	2	17018588
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	1.47e-05	2	134	2	20506482
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	1.47e-05	2	134	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	1.47e-05	2	134	2	26800705
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	1.47e-05	2	134	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	1.47e-05	2	134	2	23918728
Pubmed	Differential regulation of CYP3A4 and CYP3A7 by dimethylsulfoxide in primary human hepatocytes.	CYP3A7 CYP3A4	1.47e-05	2	134	2	15379787
Pubmed	The 5th International p63/p73 Workshop: much more than just tumour suppression.	TP63 TP73	1.47e-05	2	134	2	22240899
Pubmed	Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization.	TP63 TP73	1.47e-05	2	134	2	27716744
Pubmed	Conformational stability and activity of p73 require a second helix in the tetramerization domain.	TP63 TP73	1.47e-05	2	134	2	19763140
Pubmed	Murine complement C4 is not required for experimental autoimmune encephalomyelitis.	C4A C4B	1.47e-05	2	134	2	15390104
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	1.47e-05	2	134	2	3037333
Pubmed	Polymorphisms in the p63 and p73 genes are associated with ovarian cancer risk and clinicopathological variables.	TP63 TP73	1.47e-05	2	134	2	23095717
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	1.47e-05	2	134	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	1.47e-05	2	134	2	4216347
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	1.47e-05	2	134	2	1699796
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	1.47e-05	2	134	2	6950384
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	1.47e-05	2	134	2	2997024
Pubmed	p73 and p63 regulate the expression of fibroblast growth factor receptor 3.	TP63 TP73	1.47e-05	2	134	2	20298673
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	1.47e-05	2	134	2	8660986
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	1.47e-05	2	134	2	3624865
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	1.47e-05	2	134	2	8428773
Pubmed	GAK rs1564282 and DGKQ rs11248060 increase the risk for Parkinson's disease in a Chinese population.	GAK DGKQ	1.47e-05	2	134	2	23618683
Pubmed	Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.	C4A C4B	1.47e-05	2	134	2	21857912
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	1.47e-05	2	134	2	24638111
Pubmed	Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.	C4A C4B	1.47e-05	2	134	2	6208559
Pubmed	The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.	C4A C4B	1.47e-05	2	134	2	4514997
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	1.47e-05	2	134	2	21345967
Pubmed	The inheritance of susceptibility to the Gross leukemia virus in mice.	C4A C4B	1.47e-05	2	134	2	5919331
Pubmed	Deubiquitinase USP33 promotes the glycolysis and growth of osteosarcoma by modifying PFKFB3 ubiquitination and degradation.	PFKFB3 USP33	1.47e-05	2	134	2	37034227
Pubmed	An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.	C4A C4B	1.47e-05	2	134	2	3167981
Pubmed	Dynamics of Cytosine Methylation in the Proximal Promoters of CYP3A4 and CYP3A7 in Pediatric and Prenatal Livers.	CYP3A7 CYP3A4	1.47e-05	2	134	2	26772622
Pubmed	The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.	C4A C4B	1.47e-05	2	134	2	7545960
Pubmed	Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny.	CYP3A7 CYP3A4	1.47e-05	2	134	2	26921389
Pubmed	Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine.	CYP3A7 CYP3A4	1.47e-05	2	134	2	11940601
Pubmed	Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.	C4A C4B	1.47e-05	2	134	2	30041577
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	1.47e-05	2	134	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	1.47e-05	2	134	2	2302180
Pubmed	Complete cDNA sequence of the fourth component of murine complement.	C4A C4B	1.47e-05	2	134	2	3862104
Pubmed	The BS variant of C4 protects against age-related loss of white matter microstructural integrity.	C4A C4B	1.47e-05	2	134	2	34358307
Pubmed	Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.	C4A C4B	1.47e-05	2	134	2	18360261
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	1.47e-05	2	134	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	1.47e-05	2	134	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	1.47e-05	2	134	2	29080553
Pubmed	Schizophrenia risk from complex variation of complement component 4.	C4A C4B	1.47e-05	2	134	2	26814963
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	1.47e-05	2	134	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	1.47e-05	2	134	2	25339671
Cytoband	1p36.21	PRAMEF33 PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	1.21e-06	63	134	5	1p36.21
Cytoband	Ensembl 112 genes in cytogenetic band chr1p36	PRAMEF33 PRAMEF10 PRAMEF19 PRAMEF18 LUZP1 VPS13D SPEN ANGPTL7 TP73	1.86e-04	681	134	9	chr1p36
Cytoband	1p36	LUZP1 SPEN ANGPTL7	3.59e-04	47	134	3	1p36
Cytoband	14q31.3	ZC3H14 PTPN21	6.46e-04	13	134	2	14q31.3
Cytoband	22q13.2	EFCAB6 ADSL XPNPEP3	7.37e-04	60	134	3	22q13.2
Cytoband	19q13.13	WDR87 IFNL2	8.66e-04	15	134	2	19q13.13
GeneFamily	PRAME family	PRAMEF10 PRAMEF22 PRAMEF19 PRAMEF18	5.65e-06	24	90	4	686
GeneFamily	6-phosphofructo-2-kinases/fructose-2,6-biphosphatases	PFKFB1 PFKFB3	1.46e-04	4	90	2	1077
GeneFamily	Cytochrome P450 family 3	CYP3A7 CYP3A4	6.73e-04	8	90	2	1002
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	8.62e-04	9	90	2	1234
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	UNC13D PTPN21 FREM3 ABCA7 DST LMO7 ANGPTL7	1.45e-06	184	134	7	ca940a4f4970285ed284d5517d142abab0682044
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CYP3A4 PFKFB1 IDI2 TRIP13 CDC6 PLS1 TP73	1.92e-06	192	134	7	d6f656be2698bd215717d35f4e7ab727c08c61e0
ToppCell	AT1_cells\|World / lung cells shred on cell class, cell subclass, sample id	UNC13D PTPN21 ABCA7 CCDC85A DST LMO7 ANGPTL7	2.13e-06	195	134	7	792d6a49b0a875a00569071183d195287a9925c5
ToppCell	PND01-03-samps\|World / Age Group, Lineage, Cell class and subclass	EFCAB6 UNC13D SLFN5 MDN1 LMO7 ANKRD33B	9.41e-06	161	134	6	1973b112d8d67aacc02751797d0148e7b53bfa66
ToppCell	AT1_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	UNC13D PTPN21 ABCA7 DST LMO7 ANGPTL7	1.77e-05	180	134	6	e1964002681f80d8d62406b6ee52a01e1829ccf2
ToppCell	AT1-AT2_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	PTPN21 ABCA7 CCDC85A USP54 ANGPTL7 ANKRD33B	2.26e-05	188	134	6	be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCell	AT1_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	UNC13D PTPN21 ABCA7 CCDC85A DST LMO7	2.55e-05	192	134	6	0444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BICD2 IGSF10 DST LMO7 USP54 ANGPTL7	2.86e-05	196	134	6	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BICD2 IGSF10 DST LMO7 USP54 ANGPTL7	2.86e-05	196	134	6	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	Epithelial_cells-AT1_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	UNC13D ABCA7 CCDC85A DST LMO7 ANGPTL7	2.86e-05	196	134	6	6c99d29162848161c1f166a032320f87a5d5a631
ToppCell	(7)_Epithelial-I_(AT1)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	PTPN21 FREM3 ABCA7 CCDC85A DST LMO7	2.86e-05	196	134	6	150554fa06868d29b0608189862eef6505ba757f
ToppCell	ASK452-Epithelial-Type_1\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	UNC13D PTPN21 ABCA7 DST LMO7 USP54	2.94e-05	197	134	6	dc0a6dca4af6b216357b06f67203274f8b2a8bb0
ToppCell	AT1_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	UNC13D ABCA7 CCDC85A DST LMO7 ANGPTL7	2.94e-05	197	134	6	80d81be244c94c435accb643449b4ce6a3462c7f
ToppCell	Biopsy_IPF-Epithelial-AT1\|Biopsy_IPF / Sample group, Lineage and Cell type	UNC13D PTPN21 ABCA7 CCDC85A DST LMO7	3.03e-05	198	134	6	75bdecbe111fededf6082b11de18b84ca308ef6d
ToppCell	Sepsis-URO-Lymphocyte-T/NK-MAIT\|URO / Disease, condition lineage and cell class	RBL1 KLHL35 TRIP13 FAF1 IGSF10 PLS1	3.03e-05	198	134	6	75db638278d4be2b0f406cd8871058a8352c5a86
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	UNC13D FREM3 ABCA7 CCDC85A DST LMO7	3.11e-05	199	134	6	5a002d49a8b84c158f7b4d7a3e78e6a937757bb7
Disease	etiocholanolone glucuronide measurement	CYP3A7 CYP3A4 AKR1D1	6.68e-05	19	124	3	EFO_0800362
Disease	tacrolimus measurement	CYP3A7 CYP3A4	1.05e-04	4	124	2	EFO_0008458
Disease	estrone conjugate measurement	CYP3A7 CYP3A4	1.05e-04	4	124	2	EFO_0007971
Disease	testicular cancer (implicated_via_orthology)	TP63 TP73	1.74e-04	5	124	2	DOID:2998 (implicated_via_orthology)
Disease	tauro-beta-muricholate measurement	CYP3A7 CYP3A4	1.74e-04	5	124	2	EFO_0800213
Disease	Polycystic Kidney - body part	MKS1 PKD1	1.74e-04	5	124	2	C1567435
Disease	glyco-beta-muricholate measurement	CYP3A7 CYP3A4	1.74e-04	5	124	2	EFO_0800569
Disease	dehydroisoandrosterone sulfate DHEA-S measurement	CYP3A7 CYP3A4	2.60e-04	6	124	2	EFO_0021119
Disease	androstenediol (3beta,17beta) monosulfate (1) measurement	CYP3A7 CYP3A4	2.60e-04	6	124	2	EFO_0800294
Disease	X-24574 measurement	CYP3A7 CYP3A4	3.63e-04	7	124	2	EFO_0800897
Disease	androstenediol (3beta,17beta) disulfate (1) measurement	CYP3A7 CYP3A4	6.19e-04	9	124	2	EFO_0800278
Disease	4-androsten-3alpha,17alpha-diol monosulfate (3) measurement	CYP3A7 CYP3A4	7.71e-04	10	124	2	EFO_0022090
Disease	5alpha-androstan-3beta,17alpha-diol disulfate measurement	CYP3A7 CYP3A4	7.71e-04	10	124	2	EFO_0800289
Disease	DNA repair protein RAD51 homolog 4 measurement	CYP3A7 CYP3A4	9.40e-04	11	124	2	EFO_0801531
Disease	androstenediol (3beta,17beta) monosulfate (2) measurement	CYP3A7 CYP3A4	9.40e-04	11	124	2	EFO_0800295
Disease	cancer (implicated_via_orthology)	RBL1 SQLE IDI2 DST TP63 TP73	9.69e-04	268	124	6	DOID:162 (implicated_via_orthology)
Disease	5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement	CYP3A7 CYP3A4	1.12e-03	12	124	2	EFO_0800291
Disease	androstenediol (3alpha, 17alpha) monosulfate (3) measurement	CYP3A7 CYP3A4	1.33e-03	13	124	2	EFO_0800293
Disease	5alpha-pregnan-3beta,20beta-diol monosulfate (1) measurement	CYP3A7 CYP3A4	1.33e-03	13	124	2	EFO_0800284
Disease	X-21470 measurement	CYP3A7 CYP3A4	1.54e-03	14	124	2	EFO_0800817
Disease	5alpha-androstan-3alpha,17alpha-diol monosulfate measurement	CYP3A7 CYP3A4	1.54e-03	14	124	2	EFO_0800283
Disease	16a-hydroxy DHEA 3-sulfate measurement	CYP3A7 CYP3A4	1.77e-03	15	124	2	EFO_0800301
Disease	X-21410 measurement	CYP3A7 CYP3A4	2.02e-03	16	124	2	EFO_0800813
Disease	andro steroid monosulfate C19H28O6S (1) measurement	CYP3A7 CYP3A4	2.02e-03	16	124	2	EFO_0800305
Disease	alpha-L-iduronidase measurement	GAK DGKQ	2.29e-03	17	124	2	EFO_0020139
Disease	5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement	CYP3A7 CYP3A4	2.56e-03	18	124	2	EFO_0800288
Disease	metabolonic lactone sulfate measurement	CYP3A7 CYP3A4	2.86e-03	19	124	2	EFO_0800659
Disease	renal cell carcinoma (is_implicated_in)	C4A C4B TP73	3.10e-03	69	124	3	DOID:4450 (is_implicated_in)
Disease	androsterone glucuronide measurement	CYP3A7 CYP3A4	3.17e-03	20	124	2	EFO_0800317
Disease	Arthrogryposis	BICD2 ASCC1	3.49e-03	21	124	2	C0003886
Disease	Joubert syndrome 1	MKS1 TRIM37	3.49e-03	21	124	2	C4551568
Disease	Infiltrating duct carcinoma of female breast	CDC42BPB NRK	3.49e-03	21	124	2	C3165106
Disease	X-24947 measurement	CYP3A7 CYP3A4	3.83e-03	22	124	2	EFO_0800910
Disease	5alpha-androstan-3beta,17beta-diol disulfate measurement	CYP3A7 CYP3A4	3.83e-03	22	124	2	EFO_0021115

Protein segments in the cluster

Peptide	Gene	Start	Entry
ELMRTLREVRQPKRI	PRAMEF33	436	A0A0G2JMD5
MSLVIRNLQRVIPIR	YBEY	1	P58557
RQMLLELTRRGQEPL	BCL2L13	161	Q9BXK5
QEIPFRLREIMRSRQ	CCDC137	61	Q6PK04
LVQRLEPVIMELERQ	PFKFB1	371	P16118
ARVTLMQLPTRQEIR	EIF3B	491	P55884
RREPMNIYNLIAIIR	BICD2	621	Q8TD16
MSVRRFEQLELRPVL	C4B	841	P0C0L5
EMVRPTLERTLRVLQ	AKR1D1	96	P51857
TAMLLALQRPELVER	ABHD11	146	Q8NFV4
MQFDLIPELRAVLRR	ARFGEF1	1811	Q9Y6D6
IRRLRDFQEVELILM	ANKRD40CL	71	Q53H64
LMDEQPLLDRLQDIR	DGKQ	461	P52824
PLLDRLQDIRQMSVR	DGKQ	466	P52824
MEVLRPQLIRIDGRN	ASCC1	1	Q8N9N2
PMLLVLRNINTVRAI	ADCK5	476	Q3MIX3
QIQQELETPMRERFR	CEP83	121	Q9Y592
DPLVRRQRVQDLMAQ	CAPRIN1	351	Q14444
LRLELQMVETERVRL	EFCC1	496	Q9HA90
MYRRRQPVQLLVELL	ABCA7	16	Q8IZY2
RVDAVRLMQRLLERP	ANKRD33B	236	A6NCL7
PEEVAARLQRMQREL	RAVER2	51	Q9HCJ3
ELQRMEQEAERRRQP	RBM25	561	P49756
MNILAPVRRDRVLAE	RAB34	1	Q9BZG1
IRLQMQDDNERIRPP	RASSF2	66	P50749
TVLRLMIRQRLEEIA	RASSF2	306	P50749
AERILFNMRPRELVD	ITPR2	2061	Q14571
RLGEPIELRRAMNVI	MPEG1	631	Q2M385
LAERPDLVERVMVTR	CAPN15	561	O75808
LQAPLRRFLRQEMVI	ARHGEF17	1281	Q96PE2
RLSRQPTRLRVEMED	ANGPTL7	211	O43827
VIRGDTLRMELPQRD	PLOD3	466	O60568
EFILMELTRRPELQI	OR8K5	11	Q8NH50
ANIRRMRRIIAEDPE	TCTE1	56	Q5JU00
LEQLLVVMDRIRSFP	MDN1	3751	Q9NU22
MAEVRVQLLLSRRPE	NUDT17	1	P0C025
KPDILILRQIMALRV	GPC4	456	O75487
LRPEVERLEMLQQIA	DST	376	Q03001
GRIIEMQRLEIQRLR	CFAP57	1201	Q96MR6
LNRMIQRLRAEIEGV	KRT3	421	P12035
RPRQILAFELRMNII	KIAA1109	376	Q2LD37
IQRNVLMRRDIPNLT	FANCM	316	Q8IYD8
VDKVSRRQRPDMNIL	HECTD2	401	Q5U5R9
NETLRLFPIAMRLER	CYP3A4	361	P08684
ISRPRRVELAVMLNL	PDX1	171	P52945
APNAVRQEMIRRENL	PLS1	561	Q14651
ALQDTLRRMQLERRP	PNMA6F	396	A0A0J9YX94
VLVRVIGDLMQRIQR	FHIP2B	661	Q86V87
IRQPEMIPRINAELL	MORC3	476	Q14149
DLIRRTMETPLDRNI	PCDH9	786	Q9HC56
VIPRALMDLLQLTRE	KIF22	146	Q14807
LVQRLEPVIMELERQ	PFKFB3	366	Q16875
TPLQAELMRILREVR	PRAMEF18	431	Q5VWM3
ERQQILQEMRKRTPL	LMO7	1466	Q8WWI1
VIIAVRADLLDPRMN	MYCLP1	181	P12525
LIQPFIDLRQRIMVI	MOCOS	636	Q96EN8
LPRALQQVFRMIEER	KIF9	116	Q9HAQ2
PRRIADQVRLEQVMA	PNMA2	286	Q9UL42
RPRRVEMANLLNLTE	HOXD3	221	P31249
LQQRREMLRDPELRS	CDC42BPB	1566	Q9Y5S2
RRMPRVRSLFQEQEE	PNOC	96	Q13519
NEVLDIPRVLDMLRQ	PTPN21	1131	Q16825
PALKIVMIRDDLQVR	PPP4R3C	366	Q6ZMV5
PRQQLLTLRELEMIG	TRIP13	346	Q15645
MNRRPILIIITLEMR	TP73	266	O15350
VLDQILRMPPERNRI	FBXO38	986	Q6PIJ6
PRVLQQLVEEDRMRR	PRRT2	216	Q7Z6L0
MNRRPILIIVTLETR	TP63	316	Q9H3D4
LIRAMLQVNPEERLS	GAK	291	O14976
RRRREIENMILNDPD	ACOX1	31	Q15067
RRQLQRLEEMLIVVD	IDI2	11	Q9BXS1
VQLEVLEMLRRPTFR	IGSF10	2326	Q6WRI0
ERIPLNRTMRLVFEI	DNAH17	2231	Q9UFH2
QERLMPRILLANRNE	GCDH	76	Q92947
RRIITDFLMPLTREQ	EFCAB6	96	Q5THR3
LREQMLNEPLVREIV	GAN	231	Q9H2C0
LTPEERMELENIRRR	CYTH2	11	Q99418
ETRVLVDIRGEMPRN	SQLE	341	Q14534
LRQLQVRERPMALEA	IFNL2	86	Q8IZJ0
LRRIQMGIDQTVPLL	BORCS5	156	Q969J3
RLPAREREMDVIRNF	CDC6	171	Q99741
RVRQLEEENRMLPQA	CCDC85A	426	Q96PX6
LPRVEMALEALRNVI	DNAJC13	1746	O75165
MLAEIEVLRQRVLRI	LUZP1	61	Q86V48
EEMALSPRQQRRQLR	GPATCH2L	26	Q9NWQ4
PVRLNDVMLRLVTEL	GRID1	146	Q9ULK0
RRARQVLRVNLEPMV	CCDC71L	211	Q8N9Z2
VLRVNLEPMVRLRRF	CCDC71L	216	Q8N9Z2
RKILLDVRPDRQTVM	DDX53	391	Q86TM3
INVMNDRDPRLRERS	AHCTF1	976	Q8WYP5
RQIVERQPRMLDFRV	FAF1	91	Q9UNN5
NETLRLFPVAMRLER	CYP3A7	361	P24462
RVVGDLMLRIQRIQD	FHIP2A	696	Q5W0V3
ICIQREMVPARIRVL	CA5BP1	131	Q8WTZ4
MSVRRFEQLELRPVL	C4A	841	P0C0L4
RILMRSRVLNEEPLT	PKD1	2761	P98161
ISDLVRRRVLPMQVQ	PAMR1	351	Q6UXH9
LRRAARVLMPLQAQV	NRK	471	Q7Z2Y5
QVMRVQIRSLDNRLP	FREM3	1646	P0C091
RRRLMELISLVQEVE	TRIM37	151	O94972
VEFPETLLMDRIRLQ	TCP11X2	211	Q5H9J9
MRRDVRILLLGEAQV	RHOT2	1	Q8IXI1
MSNLPQEFRERIERL	RBL1	111	P28749
ITRPMDLQTLRENVR	TAF1	1421	P21675
TPLQAELMRILREVR	PRAMEF19	431	Q5SWL8
ELMRILREVREPNRI	PRAMEF19	436	Q5SWL8
QAELMRILREVREPK	PRAMEF22	436	A3QJZ6
RRIRQELPFMATENI	ADSL	371	P30566
RVLRVLDQFQVMPLQ	SORCS2	951	Q96PQ0
VPELRMLDDIRSRLQ	PPP1R16A	206	Q96I34
MRIILEALRQAENEP	SCG2	111	P13521
MVQLLRPQDDIRLAA	SSH3	101	Q8TE77
MQTQEILRILRLPEL	ACSL6	1	Q9UKU0
AIMTNNVPIARILLR	ANKFN1	181	Q8N957
QLEMLREVGQRLRLE	ULBP3	91	Q9BZM4
QMRRPFLERRDLIIQ	TSPYL2	246	Q9H2G4
RRRMQEARESLPQDL	MKS1	536	Q9NXB0
PLRIAQRMRLEATQL	SPEN	3546	Q96T58
ARERAIVPLEARMKQ	TCERG1	651	O14776
IRLVRVNEDTMELIR	SLC27A4	416	Q6P1M0
LRAVERIPEEQRIAM	RNF123	936	Q5XPI4
RIPEEQRIAMVRNLL	RNF123	941	Q5XPI4
LVNRPNIREPLRMDL	UBE2L6	111	O14933
LMIAAFLQPIRDVQR	UNC93A	216	Q86WB7
ELMRTLREVRQPKRI	PRAMEF10	436	O60809
ILQPQRRVDMLRDIM	SRPRA	396	P08240
LFLRMQLVPSIEERE	ZNF333	106	Q96JL9
RPRDVEIPQFMRQIA	TOPORS	221	Q9NS56
QRLRLIKSPAEIERM	XPNPEP3	241	Q9NQH7
QLLEPRMIVRCRKQD	ATP6V1E1	126	P36543
PMTLSRQEVIRRLRE	PRPF18	76	Q99633
PRIQKLLQELLMREE	WDR87	2766	Q6ZQQ6
RQLLSRLQIDPVMAE	ZC3H14	431	Q6PJT7
ARVQRAVQMDELVPL	UNC13D	606	Q70J99
MDPRLREKQNEIILR	SLFN5	31	Q08AF3
KERRRISNLLNIMEP	USP33	721	Q8TEY7
ERIRIRRVLMNAPQI	USP54	231	Q70EL1
ALIVRNRLETPMELR	VPS13D	3051	Q5THJ4
RPRRFMDLAEVIVVI	KLHL35	291	Q6PF15
RLMNEIEFRLERTPV	MYPN	911	Q86TC9