Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR5M10 OR8D1 OR10H5 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

2.86e-1243114021GO:0004984
GeneOntologyMolecularFunctiontransmembrane transporter activity

KCNH8 SLC22A23 CFTR PKD1L1 MFSD2B SLCO4A1 SLC38A5 SLCO3A1 TCIRG1 PANX1 KCNK16 TMC4 CALHM6 ABCA10 ABCC6 SLC1A7 SLC22A7 RYR2 SLC6A1 SLC5A11 MFSD2A SLC46A3 PIEZO2 ATP8A1 SLC16A4 ABCA6 ABCA5 SLC18A2 KCNK2 HTR3D SLC26A11 CNGA1 SLC38A6

5.12e-12118014033GO:0022857
GeneOntologyMolecularFunctiontransporter activity

KCNH8 SLC22A23 CFTR PKD1L1 MFSD2B SLCO4A1 SLC38A5 SLCO3A1 TCIRG1 PANX1 KCNK16 TMC4 CALHM6 ABCA10 ABCC6 SLC1A7 SLC22A7 RYR2 SLC6A1 SLC5A11 MFSD2A SLC46A3 PIEZO2 ATP8A1 SLC16A4 ABCA6 ABCA5 SLC18A2 KCNK2 HTR3D SLC26A11 CNGA1 SLC38A6

5.39e-11128914033GO:0005215
GeneOntologyMolecularFunctionactive transmembrane transporter activity

CFTR MFSD2B SLCO4A1 SLC38A5 SLCO3A1 TCIRG1 ABCA10 ABCC6 SLC1A7 SLC22A7 SLC6A1 SLC5A11 MFSD2A SLC46A3 ATP8A1 SLC16A4 ABCA6 ABCA5 SLC18A2 SLC26A11

1.45e-1047714020GO:0022804
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR5M10 OR8D1 OR10H5 HTR1E HTR1F OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 GPR160 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 AGTR1 OR52N4 ACKR2 OR8G5 OR10G9 OR10G8 OR6C6

4.68e-1088414026GO:0004930
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

KCNH8 CFTR PKD1L1 SLC38A5 TCIRG1 PANX1 KCNK16 TMC4 CALHM6 SLC1A7 RYR2 SLC6A1 SLC5A11 MFSD2A SLC46A3 PIEZO2 ATP8A1 SLC18A2 KCNK2 HTR3D SLC26A11 CNGA1

3.43e-0879314022GO:0015075
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

MFSD2B SLCO4A1 SLC38A5 SLCO3A1 SLC1A7 SLC22A7 SLC6A1 SLC5A11 MFSD2A SLC46A3 SLC16A4 SLC18A2 SLC26A11

1.71e-0729614013GO:0015291
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR5M10 OR8D1 OR10H5 HTR1E HTR1F OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 GPR160 OR10G7 OR51S1 CD247 OR10A4 OR10H2 OR10H1 AGTR1 OR52N4 HTR3D ACKR2 OR8G5 OR10G9 OR10G8 OR6C6

1.93e-07135314028GO:0004888
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

KCNH8 PKD1L1 SLC38A5 TCIRG1 PANX1 KCNK16 CALHM6 SLC1A7 RYR2 SLC6A1 SLC5A11 MFSD2A SLC46A3 PIEZO2 ATP8A1 SLC18A2 KCNK2 HTR3D CNGA1

2.02e-0766414019GO:0008324
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

CFTR SLCO4A1 SLC38A5 SLCO3A1 PANX1 SLC1A7 SLC22A7 SLC6A1 MFSD2A SLC16A4 SLC26A11 SLC38A6

1.09e-0629314012GO:0008514
GeneOntologyMolecularFunctionodorant binding

OR5M10 OR8D1 OR5M1 OR9K2 OR5D14 OR9I1 OR6K6 OR8G5

3.17e-061271408GO:0005549
GeneOntologyMolecularFunctionmonoatomic ion channel activity

KCNH8 CFTR PKD1L1 PANX1 KCNK16 TMC4 CALHM6 SLC1A7 RYR2 PIEZO2 KCNK2 HTR3D SLC26A11 CNGA1

4.39e-0645914014GO:0005216
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

KCNH8 PKD1L1 SLC38A5 PANX1 KCNK16 SLC1A7 RYR2 SLC6A1 SLC5A11 MFSD2A SLC46A3 SLC18A2 KCNK2 CNGA1

5.09e-0646514014GO:0046873
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

KCNH8 CFTR PKD1L1 SLC38A5 TCIRG1 PANX1 KCNK16 ABCC6 SLC1A7 RYR2 SLC6A1 SLC5A11 MFSD2A SLC46A3 SLC18A2 KCNK2 SLC26A11 CNGA1

6.08e-0675814018GO:0015318
GeneOntologyMolecularFunctionlipid transporter activity

MFSD2B SLCO4A1 SLCO3A1 ABCA10 SLC22A7 MFSD2A ATP8A1 ABCA6 ABCA5

1.02e-051961409GO:0005319
GeneOntologyMolecularFunctionsymporter activity

MFSD2B SLC1A7 SLC6A1 SLC5A11 MFSD2A SLC46A3 SLC16A4 SLC18A2

1.09e-051501408GO:0015293
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

CFTR TCIRG1 ABCA10 ABCC6 ATP8A1 ABCA6 ABCA5

1.18e-051091407GO:0042626
GeneOntologyMolecularFunctionchannel activity

KCNH8 CFTR PKD1L1 PANX1 KCNK16 TMC4 CALHM6 SLC1A7 RYR2 PIEZO2 KCNK2 HTR3D SLC26A11 CNGA1

1.99e-0552514014GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

KCNH8 CFTR PKD1L1 PANX1 KCNK16 TMC4 CALHM6 SLC1A7 RYR2 PIEZO2 KCNK2 HTR3D SLC26A11 CNGA1

2.04e-0552614014GO:0022803
GeneOntologyMolecularFunctionABC-type transporter activity

CFTR ABCA10 ABCC6 ABCA6 ABCA5

2.35e-05491405GO:0140359
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

KCNH8 PKD1L1 SLC38A5 TCIRG1 PANX1 KCNK16 SLC1A7 RYR2 SLC6A1 SLC5A11 MFSD2A SLC46A3 SLC18A2 KCNK2 CNGA1

3.51e-0562714015GO:0022890
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

SLCO4A1 SLCO3A1 SLC22A7

1.16e-04141403GO:0015132
GeneOntologyMolecularFunctiongated channel activity

KCNH8 CFTR KCNK16 TMC4 SLC1A7 RYR2 PIEZO2 KCNK2 HTR3D CNGA1

1.26e-0433414010GO:0022836
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

SLCO4A1 SLCO3A1 SLC22A7

1.44e-04151403GO:0071714
GeneOntologyMolecularFunctionmonoatomic cation channel activity

KCNH8 PKD1L1 PANX1 KCNK16 CALHM6 RYR2 PIEZO2 KCNK2 HTR3D CNGA1

1.56e-0434314010GO:0005261
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC38A5 SLC1A7 SLC6A1 SLC5A11 MFSD2A SLC18A2 CNGA1

2.06e-041711407GO:0015081
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLCO4A1 SLCO3A1 SLC22A7

2.55e-04181403GO:0015347
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC1A7 SLC6A1 SLC5A11 MFSD2A SLC18A2

2.63e-04811405GO:0015370
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

CFTR TCIRG1 ABCA10 ABCC6 ATP8A1 ABCA6 ABCA5

2.64e-041781407GO:0015399
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC38A5 TCIRG1 SLC1A7 SLC6A1 SLC5A11 MFSD2A ATP8A1 SLC18A2 SLC26A11

2.78e-043011409GO:0022853
GeneOntologyMolecularFunctionDNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

TOP2A TOP2B

2.90e-0441402GO:0003918
GeneOntologyMolecularFunctionnarrow pore channel activity

PANX1 KCNK16 KCNK2

3.01e-04191403GO:0022842
GeneOntologyMolecularFunctionleak channel activity

PANX1 KCNK16 KCNK2

3.01e-04191403GO:0022840
GeneOntologyMolecularFunctionATP-dependent activity

MYO9B CFTR TCIRG1 ARID1A ABCA10 ABCC6 MFSD2A ATP8A1 ABCA6 ABCA5 YME1L1 TOP2A TOP2B

3.91e-0461414013GO:0140657
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC38A5 SLC1A7 SLC22A7 SLC6A1 MFSD2A SLC16A4 SLC38A6

6.53e-042071407GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC38A5 SLC1A7 SLC22A7 SLC6A1 MFSD2A SLC16A4 SLC38A6

6.71e-042081407GO:0005342
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

CFTR PANX1 SLC1A7 SLC6A1 SLC18A2 SLC26A11

6.91e-041511406GO:0008509
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

CFTR ABCC6 SLC1A7 SLC6A1 SLC18A2 SLC26A11

1.32e-031711406GO:0015103
GeneOntologyMolecularFunctionDNA topoisomerase activity

TOP2A TOP2B

1.33e-0381402GO:0003916
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC1A7 SLC6A1 SLC5A11 MFSD2A SLC18A2

1.52e-031191405GO:0015294
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

CFTR RYR2 CNGA1

1.58e-03331403GO:0005217
GeneOntologyMolecularFunctionL-glutamine transmembrane transporter activity

SLC38A5 SLC38A6

1.70e-0391402GO:0015186
GeneOntologyMolecularFunctionsnoRNA binding

WDR3 NOP14 PRKDC

1.72e-03341403GO:0030515
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

SLCO4A1 SLCO3A1 SLC22A7 MFSD2A

1.73e-03731404GO:0170055
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

CFTR SLC1A7 SLC6A1 SLC18A2 SLC26A11

1.89e-031251405GO:0015108
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

CFTR ABCC6

2.12e-03101402GO:0043225
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC38A5 SLC1A7 SLC38A6

2.96e-03411403GO:0015175
GeneOntologyMolecularFunctionRoundabout binding

MYO9B SLIT2

3.08e-03121402GO:0048495
GeneOntologyMolecularFunctionserotonin binding

HTR1E HTR1F

3.62e-03131402GO:0051378
GeneOntologyMolecularFunctionGTPase inhibitor activity

IQGAP2 SLIT2

3.62e-03131402GO:0005095
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water

FADS1 DEGS2

3.62e-03131402GO:0016717
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

MFSD2A ATP8A1

4.20e-03141402GO:0140333
GeneOntologyBiologicalProcesssensory perception of smell

OR5M10 OR8D1 OR10H5 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 BBS1 OR6K6 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

7.85e-1346514022GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR5M10 OR8D1 OR10H5 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

1.63e-1243214021GO:0050911
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR5M10 OR8D1 OR10H5 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 RYR2 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

8.29e-1252414022GO:0009593
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR5M10 OR8D1 OR10H5 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

1.46e-1148514021GO:0050907
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR5M10 OR8D1 OR10H5 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 BBS1 OR6K6 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

1.91e-1154714022GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR5M10 OR8D1 OR10H5 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 OR10G7 OR51S1 PIEZO2 OR10A4 OR10H2 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

6.31e-1158214022GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

OR5M10 OR8D1 OR10H5 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 PKD1L1 OR2C3 OR6K6 RYR2 OR10G7 OR51S1 PIEZO2 OR10A4 OR10H2 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

1.09e-1072214024GO:0051606
GeneOntologyBiologicalProcesssensory perception

OR5M10 OR8D1 OR10H5 EYA4 OR5M1 OR9K2 WFS1 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 BBS1 ABCC6 OR6K6 OR10G7 OR51S1 PIEZO2 HMCN1 OR10A4 OTOF OR10H2 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6 CNGA1

1.32e-10107214029GO:0007600
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR5M10 OR8D1 OR10H5 HTR1E HTR1F OR5M1 OR9K2 IQGAP2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 MFSD2B OR6K6 GPR160 OR10G7 SLIT2 OR51S1 OR10A4 OR10H2 OR10H1 AGTR1 OR52N4 KCNK2 ACKR2 OR8G5 OR10G9 OR10G8 OR6C6 PIK3R5 PMCHL2

7.95e-10139514032GO:0007186
GeneOntologyBiologicalProcessmonoatomic ion transport

KCNH8 WFS1 SLC22A23 CFTR PKD1L1 SLCO4A1 SLC38A5 SLCO3A1 TCIRG1 PANX1 KCNK16 TMC4 CALHM6 ABCC6 SLC1A7 SLC22A7 RYR2 SLC6A1 SLC5A11 SLC46A3 PIEZO2 ATP8A1 MTOR SLC18A2 AGTR1 KCNK2 HTR3D SLC26A11 CNGA1

3.66e-08137414029GO:0006811
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

KCNH8 CFTR PKD1L1 SLC38A5 TCIRG1 PANX1 KCNK16 TMC4 CALHM6 ABCC6 SLC1A7 RYR2 SLC6A1 SLC46A3 PIEZO2 ATP8A1 MTOR SLC18A2 AGTR1 KCNK2 HTR3D SLC26A11 CNGA1

1.74e-06111514023GO:0034220
GeneOntologyBiologicalProcesspositive regulation of single stranded viral RNA replication via double stranded DNA intermediate

TOP2A TOP2B

4.57e-0521402GO:0045870
GeneOntologyBiologicalProcessorganic anion transport

CFTR SLCO4A1 SLC38A5 SLCO3A1 PANX1 ABCC6 SLC1A7 SLC22A7 SLC6A1 MFSD2A SLC16A4 SLC26A11 SLC38A6

5.05e-0551514013GO:0015711
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

CFTR PANX1 ABCC6 SLC1A7 SLC6A1 MTOR SLC26A11

8.49e-051531407GO:0098656
GeneOntologyBiologicalProcesscarboxylic acid transport

SLCO4A1 SLC38A5 SLCO3A1 ABCC6 SLC1A7 SLC22A7 SLC6A1 MFSD2A SLC16A4 SLC26A11 SLC38A6

1.15e-0441014011GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

SLCO4A1 SLC38A5 SLCO3A1 ABCC6 SLC1A7 SLC22A7 SLC6A1 MFSD2A SLC16A4 SLC26A11 SLC38A6

1.20e-0441214011GO:0015849
GeneOntologyBiologicalProcessvascular process in circulatory system

CFTR SLC38A5 SLCO3A1 BCR PTGS1 SLC6A1 SLIT2 MFSD2A ATP8A1 AGTR1

1.23e-0434414010GO:0003018
GeneOntologyBiologicalProcesslipid localization

CFTR MFSD2B SLCO4A1 SLCO3A1 ABCA10 SLC22A7 MFSD2A ATP8A1 ABCA6 ABCA5 LPCAT3 AGTR1 FBXW7

1.28e-0456514013GO:0010876
GeneOntologyBiologicalProcessresponse to nitrogen compound

WFS1 UGGT1 CFTR PANX1 CASTOR2 ADTRP ERBIN SERPINA12 RYR2 SLC6A1 SLIT2 DUOX1 PPP5C MTOR SLC18A2 RPTOR AGTR1 HTR3D PRKDC EIF2AK3 TOP2B

1.36e-04127214021GO:1901698
GeneOntologyBiologicalProcessnegative regulation of mononuclear cell migration

ADTRP BCR STAP1 SLIT2

1.39e-04391404GO:0071676
GeneOntologyBiologicalProcesslipid transport

CFTR MFSD2B SLCO4A1 SLCO3A1 ABCA10 SLC22A7 MFSD2A ATP8A1 ABCA6 ABCA5 LPCAT3 AGTR1

1.77e-0450614012GO:0006869
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

KCNH8 CFTR PKD1L1 SLC38A5 TCIRG1 PANX1 KCNK16 SLC1A7 RYR2 SLC6A1 SLC46A3 MTOR SLC18A2 AGTR1 KCNK2 HTR3D SLC26A11 CNGA1

1.84e-04101714018GO:0098660
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

KCNH8 CFTR PKD1L1 SLC38A5 TCIRG1 PANX1 KCNK16 CALHM6 RYR2 SLC6A1 SLC46A3 PIEZO2 ATP8A1 SLC18A2 AGTR1 KCNK2 CNGA1

2.24e-0494214017GO:0098655
GeneOntologyBiologicalProcessmonoatomic anion transport

CFTR PANX1 ABCC6 SLC1A7 SLC6A1 MTOR SLC26A11

2.57e-041831407GO:0006820
GeneOntologyBiologicalProcessregulation of inorganic anion transmembrane transport

CFTR MTOR

2.72e-0441402GO:1903795
GeneOntologyBiologicalProcesspositive regulation of pentose-phosphate shunt

MTOR RPTOR

2.72e-0441402GO:1905857
GeneOntologyBiologicalProcessmonoatomic cation transport

KCNH8 WFS1 CFTR PKD1L1 SLC38A5 TCIRG1 PANX1 KCNK16 CALHM6 RYR2 SLC6A1 SLC5A11 SLC46A3 PIEZO2 ATP8A1 SLC18A2 AGTR1 KCNK2 CNGA1

3.12e-04115714019GO:0006812
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC38A5 SLCO3A1 SLC6A1 MFSD2A ATP8A1

3.17e-04871405GO:0150104
GeneOntologyBiologicalProcessvascular transport

SLC38A5 SLCO3A1 SLC6A1 MFSD2A ATP8A1

3.34e-04881405GO:0010232
GeneOntologyCellularComponentendoplasmic reticulum membrane

WFS1 CFTR PANX1 LBR TM6SF2 PTGS1 ABCC6 OR6K6 RYR2 MFSD2A FADS1 BCAP29 OR10A4 OTOF MTOR LPCAT3 SEC11A KCNK2 UGT2B4 DEGS2 TRAM2 EIF2AK3

6.09e-05129314222GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

WFS1 CFTR PANX1 LBR TM6SF2 PTGS1 ABCC6 OR6K6 RYR2 MFSD2A FADS1 BCAP29 OR10A4 OTOF MTOR LPCAT3 SEC11A KCNK2 UGT2B4 DEGS2 TRAM2 EIF2AK3

6.52e-05129914222GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

WFS1 CFTR PANX1 LBR TM6SF2 PTGS1 ABCC6 OR6K6 RYR2 MFSD2A FADS1 BCAP29 OR10A4 OTOF MTOR LPCAT3 SEC11A KCNK2 UGT2B4 DEGS2 TRAM2 EIF2AK3

8.91e-05132714222GO:0042175
GeneOntologyCellularComponentbasolateral plasma membrane

CFTR SLCO4A1 SLCO3A1 ERBIN ABCC6 SLC22A7 OTOF AGTR1 SLC26A11

3.47e-043201429GO:0016323
GeneOntologyCellularComponentTORC1 complex

MTOR RPTOR

6.75e-0461422GO:0031931
GeneOntologyCellularComponentbasal plasma membrane

CFTR SLCO4A1 SLCO3A1 ERBIN ABCC6 SLC22A7 OTOF AGTR1 SLC26A11

7.18e-043541429GO:0009925
DomainOlfact_rcpt

OR5M10 OR8D1 OR10H5 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

2.62e-1239314321IPR000725
DomainGPCR_Rhodpsn_7TM

OR5M10 OR8D1 OR10H5 HTR1E HTR1F OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 GPR160 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 AGTR1 OR52N4 ACKR2 OR8G5 OR10G9 OR10G8 OR6C6

7.61e-1267014326IPR017452
DomainG_PROTEIN_RECEP_F1_1

OR5M10 OR8D1 OR10H5 HTR1E HTR1F OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 GPR160 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 AGTR1 OR52N4 ACKR2 OR8G5 OR10G9 OR10G8 OR6C6

1.25e-1168514326PS00237
DomainG_PROTEIN_RECEP_F1_2

OR5M10 OR8D1 OR10H5 HTR1E HTR1F OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 GPR160 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 AGTR1 OR52N4 ACKR2 OR8G5 OR10G9 OR10G8 OR6C6

1.51e-1169114326PS50262
DomainGPCR_Rhodpsn

OR5M10 OR8D1 OR10H5 HTR1E HTR1F OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 GPR160 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 AGTR1 OR52N4 ACKR2 OR8G5 OR10G9 OR10G8 OR6C6

1.56e-1169214326IPR000276
Domain7tm_1

OR5M10 OR8D1 OR10H5 HTR1E HTR1F OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 AGTR1 OR52N4 ACKR2 OR8G5 OR10G9 OR10G8 OR6C6

5.85e-1167714325PF00001
DomainMFS_dom

SLC22A23 MFSD2B SLCO4A1 SLCO3A1 SLC22A7 MFSD2A SLC46A3 SLC16A4 SLC18A2

9.10e-071341439IPR020846
DomainMFS

SLC22A23 MFSD2B SLCO4A1 SLC22A7 MFSD2A SLC46A3 SLC16A4 SLC18A2

1.79e-061081438PS50850
DomainABC_tran

CFTR ABCA10 ABCC6 ABCA6 ABCA5

3.22e-05481435PF00005
DomainABC_TRANSPORTER_2

CFTR ABCA10 ABCC6 ABCA6 ABCA5

3.22e-05481435PS50893
DomainABC_TRANSPORTER_1

CFTR ABCA10 ABCC6 ABCA6 ABCA5

3.57e-05491435PS00211
DomainABC_transporter-like

CFTR ABCA10 ABCC6 ABCA6 ABCA5

3.94e-05501435IPR003439
Domain-

TOP2A TOP2B

5.82e-05214323.40.50.670
DomainDTHCT

TOP2A TOP2B

5.82e-0521432IPR012542
DomainDNA_gyraseB

TOP2A TOP2B

5.82e-0521432PF00204
Domain-

TOP2A TOP2B

5.82e-05214323.90.199.10
DomainTopoIIA_CS

TOP2A TOP2B

5.82e-0521432IPR018522
DomainTopo_IIA

TOP2A TOP2B

5.82e-0521432IPR001241
DomainDNA_topoisoIV

TOP2A TOP2B

5.82e-0521432PF00521
DomainTopo_IIA_A/C_ab

TOP2A TOP2B

5.82e-0521432IPR013758
DomainTopo_IIA_A_a

TOP2A TOP2B

5.82e-0521432IPR013757
DomainTopo_IIA_cen_dom

TOP2A TOP2B

5.82e-0521432IPR013759
DomainTOP4c

TOP2A TOP2B

5.82e-0521432SM00434
DomainTOP2c

TOP2A TOP2B

5.82e-0521432SM00433
Domain5HT1F_rcpt

HTR1E HTR1F

5.82e-0521432IPR000450
DomainTopo_IIA-like_dom

TOP2A TOP2B

5.82e-0521432IPR013760
DomainTopo_IIA_bsu_dom2

TOP2A TOP2B

5.82e-0521432IPR013506
DomainDTHCT

TOP2A TOP2B

5.82e-0521432PF08070
Domain-

TOP2A TOP2B

5.82e-05214321.10.268.10
DomainTOPRIM_C

TOP2A TOP2B

5.82e-0521432IPR031660
DomainTOPRIM_C

TOP2A TOP2B

5.82e-0521432PF16898
DomainTopo_IIA_A/C

TOP2A TOP2B

5.82e-0521432IPR002205
DomainTOPOISOMERASE_II

TOP2A TOP2B

5.82e-0521432PS00177
DomainABC_A

ABCA10 ABCA6 ABCA5

9.19e-05121433IPR026082
DomainArg_repress_C-like

TOP2A TOP2B

1.74e-0431432IPR024946
DomainPrepro-melanin_conc_hormone

PMCHL1 PMCHL2

1.74e-0431432IPR005456
DomainPro-MCH

PMCHL1 PMCHL2

1.74e-0431432PF05824
Domain-

TOP2A TOP2B

1.74e-04314323.30.1360.40
DomainARM-like

HUWE1 ARID1A MTOR RPTOR MROH2B ANKAR PRKDC AGBL1 TANGO6

2.38e-042701439IPR011989
DomainARM-type_fold

DOCK11 HUWE1 ARID1A MTOR RPTOR MROH2B ANKAR PRKDC AGBL1 TANGO6

2.88e-0433914310IPR016024
DomainABC_transporter_CS

CFTR ABCA10 ABCC6 ABCA5

2.94e-04421434IPR017871
DomainMFS_1

SLC22A7 MFSD2A SLC46A3 SLC16A4 SLC18A2

3.11e-04771435PF07690
DomainMFS

SLC22A7 MFSD2A SLC46A3 SLC16A4 SLC18A2

3.11e-04771435IPR011701
DomainToprim

TOP2A TOP2B

3.46e-0441432PF01751
DomainToprim_domain

TOP2A TOP2B

3.46e-0441432IPR006171
DomainTOPRIM

TOP2A TOP2B

3.46e-0441432PS50880
Domain-

EFL1 TOP2A TOP2B

5.28e-042114333.30.230.10
DomainFATC

MTOR PRKDC

5.73e-0451432PF02260
DomainRibosomal_S5_D2-typ_fold_subgr

EFL1 TOP2A TOP2B

6.08e-04221433IPR014721
DomainAAA

CFTR ABCA10 ABCC6 ABCA6 ABCA5 YME1L1

8.51e-041441436SM00382
DomainAAA+_ATPase

CFTR ABCA10 ABCC6 ABCA6 ABCA5 YME1L1

8.51e-041441436IPR003593
DomainFAT

MTOR PRKDC

8.56e-0461432PS51189
DomainFATC

MTOR PRKDC

8.56e-0461432PS51190
DomainFAT

MTOR PRKDC

8.56e-0461432PF02259
DomainPIK-rel_kinase_FAT

MTOR PRKDC

8.56e-0461432IPR003151
DomainFATC_dom

MTOR PRKDC

8.56e-0461432IPR003152
DomainPIK_FAT

MTOR PRKDC

8.56e-0461432IPR014009
DomainFATC

MTOR PRKDC

8.56e-0461432SM01343
DomainCXCR4/ACKR2

AGTR1 ACKR2

1.19e-0371432IPR001277
DomainFA_desaturase_dom

FADS1 DEGS2

1.58e-0381432IPR005804
DomainFA_desaturase

FADS1 DEGS2

1.58e-0381432PF00487
Domain-

ARID1A MTOR RPTOR MROH2B ANKAR PRKDC TANGO6

1.63e-0322214371.25.10.10
Domain5HT_rcpt

HTR1E HTR1F

2.02e-0391432IPR002231
DomainHEAT_REPEAT

MTOR MROH2B PRKDC TANGO6

2.04e-03701434PS50077
DomainRibosomal_S5_D2-typ_fold

EFL1 TOP2A TOP2B

2.21e-03341433IPR020568
DomainAn_peroxidase

PTGS1 DUOX1

2.52e-03101432PF03098
DomainHaem_peroxidase_animal

PTGS1 DUOX1

2.52e-03101432IPR019791
DomainHaem_peroxidase

PTGS1 DUOX1

2.52e-03101432IPR010255
DomainPEROXIDASE_3

PTGS1 DUOX1

2.52e-03101432PS50292
Domain-

PTGS1 DUOX1

2.52e-031014321.10.640.10
DomainOA_transporter

SLCO4A1 SLCO3A1

3.65e-03121432IPR004156
DomainOATP

SLCO4A1 SLCO3A1

3.65e-03121432PF03137
DomainK_chnl_volt-dep_EAG/ELK/ERG

KCNH8 CNGA1

4.99e-03141432IPR003938
Domain2pore_dom_K_chnl

KCNK16 KCNK2

5.73e-03151432IPR003280
DomainPI3/4_kinase_CS

MTOR PRKDC

5.73e-03151432IPR018936
Domain-

MTOR PRKDC

6.51e-031614321.10.1070.11
DomainPI3Kc

MTOR PRKDC

6.51e-03161432SM00146
DomainAa_trans

SLC38A5 SLC38A6

7.34e-03171432PF01490
DomainAA_transpt_TM

SLC38A5 SLC38A6

7.34e-03171432IPR013057
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR5M10 OR8D1 OR10H5 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

2.10e-1238911021M14091
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR5M10 OR8D1 OR10H5 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

7.90e-1241711021M4072
PathwayREACTOME_SENSORY_PERCEPTION

OR5M10 OR8D1 OR10H5 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 OR10G7 OR51S1 OR10A4 OTOF OR10H2 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6 CNGA1

5.46e-1063611023M41834
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR8D1 OR10H5 OR5D14 OR13C3 OR10G7 OR10H2 OR10H1 OR10G9 OR10G8

3.37e-09701109MM14984
PathwayREACTOME_SENSORY_PERCEPTION

OR8D1 OR10H5 OR5D14 OR13C3 OR10G7 OR10H2 OR10H1 OR10G9 OR10G8 CNGA1

2.28e-0619011010MM15687
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

CFTR RAB11FIP2 SLCO4A1 SLC38A5 SLCO3A1 TCIRG1 ABCA10 ABCC6 SLC1A7 SLC22A7 RYR2 SLC6A1 SLC5A11 ATP8A1 ABCA6 ABCA5 SLC18A2 SLC26A11 YME1L1

3.74e-0673611019M27287
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

CFTR RAB11FIP2 SLCO4A1 SLC38A5 SLCO3A1 TCIRG1 ABCC6 SLC1A7 SLC22A7 RYR2 SLC6A1 SLC5A11 ATP8A1 ABCA6 ABCA5 SLC18A2 SLC26A11 YME1L1

5.03e-0668111018MM14985
PathwayKEGG_ABC_TRANSPORTERS

CFTR ABCA10 ABCC6 ABCA6 ABCA5

2.25e-05441105M11911
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLCO4A1 SLC38A5 SLCO3A1 SLC1A7 SLC22A7 SLC6A1 SLC5A11 SLC18A2 SLC26A11

1.01e-042381109MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLCO4A1 SLC38A5 SLCO3A1 SLC1A7 SLC22A7 SLC6A1 SLC5A11 SLC18A2 SLC26A11

1.43e-042491109M5988
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA10 ABCA6 ABCA5

3.46e-04181103M524
PathwayWP_ATM_SIGNALING_IN_DEVELOPMENT_AND_DISEASE

PPP5C MTOR PRKDC TP53BP1

4.83e-04471104M39518
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

SLC1A7 SLC6A1 SLC18A2 GLS

6.61e-04511104M4281
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

SLC1A7 SLC6A1 SLC18A2 GLS

6.61e-04511104MM14499
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR5M10 OR8D1 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR6K6 OR10G7 OR51S1 OR10A4 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

8.87e-143431441732295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR5M10 OR8D1 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR6K6 OR10G7 OR51S1 OR10A4 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

1.02e-133461441714611657
Pubmed

The human olfactory receptor gene family.

OR5M10 OR8D1 OR10H5 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR13C4 OR2C3 OR6K6 OR10G7 OR51S1 OR10A4 OR10H2 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8

1.24e-135411442014983052
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR5M10 OR8D1 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR10G7 OR51S1 OR10A4 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

1.09e-123401441611875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR5M10 OR8D1 OR5M1 OR9K2 OR5D14 OR9I1 OR13C3 OR10G7 OR51S1 OR10A4 OR10H1 OR52N4 OR8G5 OR10G9 OR10G8 OR6C6

1.09e-123401441611802173
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR10H5 OR5M1 OR5D14 OR9I1 OR13C4 OR2C3 OR10A4 OR10H2 OR10H1

3.60e-07219144912213199
Pubmed

The FBXW7-SHOC2-Raptor Axis Controls the Cross-Talks between the RAS-ERK and mTORC1 Signaling Pathways.

MTOR RPTOR FBXW7

1.38e-066144330865892
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCA10 ABCC6 ABCA6 ABCA5

1.95e-062214448894702
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

IQGAP2 MYO9B HUWE1 BCR SLIT2 PRKDC TOP2A FBXW7

2.98e-06211144817314511
Pubmed

The human ATP-binding cassette (ABC) transporter superfamily.

ABCA10 ABCA6 ABCA5

8.17e-0610144311435397
Pubmed

DNA damage-induced activation of ATM promotes β-TRCP-mediated ARID1A ubiquitination and destruction in gastric cancer cells.

FBXW2 ARID1A FBXW7

8.17e-0610144331210753
Pubmed

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.

MTOR RPTOR PRKDC

1.12e-0511144320427287
Pubmed

Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study.

CFTR RYR2 SLIT2

1.12e-0511144317903301
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

CFTR SLCO4A1 ABCC6 SLC22A7 ABCA6 ABCA5 UGT2B4

1.68e-05193144719343046
Pubmed

DNA topoisomerase II is dispensable for oocyte meiotic resumption but is essential for meiotic chromosome condensation and separation in mice.

TOP2A TOP2B

1.70e-052144224048577
Pubmed

The mTORC1 component RPTOR is required for maintenance of the foundational spermatogonial stem cell pool in mice†.

MTOR RPTOR

1.70e-052144230202948
Pubmed

Dual TORK/DNA-PK inhibition blocks critical signaling pathways in chronic lymphocytic leukemia.

MTOR PRKDC

1.70e-052144227235137
Pubmed

Use of divalent metal ions in the dna cleavage reaction of human type II topoisomerases.

TOP2A TOP2B

1.70e-052144219222228
Pubmed

Rethinking isolated cleft lip and palate as a syndrome.

HMCN1 IGSF9

1.70e-052144229500156
Pubmed

Evidence for a mutant allele of the gene for DNA topoisomerase II in adriamycin-resistant P388 murine leukemia cells.

TOP2A TOP2B

1.70e-05214422555055
Pubmed

Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation.

TOP2A TOP2B

1.70e-05214421331984
Pubmed

Doxorubicin-induced cardiotoxicity is maturation dependent due to the shift from topoisomerase IIα to IIβ in human stem cell derived cardiomyocytes.

TOP2A TOP2B

1.70e-052144231106979
Pubmed

A biochemical analysis of topoisomerase II alpha and beta kinase activity found in HIV-1 infected cells and virus.

TOP2A TOP2B

1.70e-052144216091284
Pubmed

Protein phosphatase 5 regulates the function of 53BP1 after neocarzinostatin-induced DNA damage.

PPP5C TP53BP1

1.70e-052144219176521
Pubmed

Regulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERK.

MTOR EIF2AK3

1.70e-052144223160380
Pubmed

Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype.

HTR1E HTR1F

1.70e-05214421608964
Pubmed

Effect of DNA methylation profile on OATP3A1 and OATP4A1 transcript levels in colorectal cancer.

SLCO4A1 SLCO3A1

1.70e-052144226349991
Pubmed

Mining topoisomerase isoforms in gastric cancer.

TOP2A TOP2B

1.70e-052144232535049
Pubmed

Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development.

TOP2A TOP2B

1.70e-05214421380833
Pubmed

DNA-PK, Nuclear mTOR, and the Androgen Pathway in Prostate Cancer.

MTOR PRKDC

1.70e-052144232209447
Pubmed

Hepatic overexpression of a dominant negative form of raptor enhances Akt phosphorylation and restores insulin sensitivity in K/KAy mice.

MTOR RPTOR

1.70e-052144218270303
Pubmed

DNA-PK controls Apollo's access to leading-end telomeres.

DCLRE1B PRKDC

1.70e-052144238407308
Pubmed

ARID1A regulates R-loop associated DNA replication stress.

ARID1A TOP2A

1.70e-052144233826602
Pubmed

Involvement of human topoisomerase II isoforms in HIV-1 reverse transcription.

TOP2A TOP2B

1.70e-052144223399433
Pubmed

Enhanced processing of UVA-irradiated DNA by human topoisomerase II in living cells.

TOP2A TOP2B

1.70e-052144215044480
Pubmed

C-terminal regions of topoisomerase IIalpha and IIbeta determine isoform-specific functioning of the enzymes in vivo.

TOP2A TOP2B

1.70e-052144217526531
Pubmed

DNA topoisomerase II distribution in mouse preimplantation embryos.

TOP2A TOP2B

1.70e-052144211835579
Pubmed

Deletion of mTORC1 Activity in CD4+ T Cells Is Associated with Lung Fibrosis and Increased γδ T Cells.

MTOR RPTOR

1.70e-052144227649073
Pubmed

Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes.

TOP2A TOP2B

1.70e-05214422556712
Pubmed

mTORC2, but not mTORC1, is required for hippocampal mGluR-LTD and associated behaviors.

MTOR RPTOR

1.70e-052144229786082
Pubmed

Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning.

MTOR RPTOR

1.70e-052144227018708
Pubmed

Using a biochemical approach to identify the primary dimerization regions in human DNA topoisomerase IIalpha.

TOP2A TOP2B

1.70e-052144210473615
Pubmed

The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity.

MTOR RPTOR

1.70e-052144216847060
Pubmed

Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain.

TOP2A TOP2B

1.70e-05214429224616
Pubmed

DNA damage response during chromatin remodeling in elongating spermatids of mice.

TOP2A TOP2B

1.70e-052144218032420
Pubmed

Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants.

TOP2A TOP2B

1.70e-052144222111588
Pubmed

Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies.

TOP2A TOP2B

1.70e-052144217578914
Pubmed

Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships.

HTR1E HTR1F

1.70e-052144221422162
Pubmed

mTOR kinase-dependent, but raptor-independent regulation of downstream signaling is important for cell cycle exit and myogenic differentiation.

MTOR RPTOR

1.70e-052144225486193
Pubmed

Topoisomerase II alpha and topoisomerase II beta genes: characterization and mapping to human chromosomes 17 and 3, respectively.

TOP2A TOP2B

1.70e-05214421309226
Pubmed

Kinetic analysis of human topoisomerase IIalpha and beta DNA binding by surface plasmon resonance.

TOP2A TOP2B

1.70e-052144214596941
Pubmed

Enhanced expression of DNA topoisomerase II genes in human medulloblastoma and its possible association with etoposide sensitivity.

TOP2A TOP2B

1.70e-052144217361331
Pubmed

Molecular cloning and characterization of the human topoisomerase IIalpha and IIbeta genes: evidence for isoform evolution through gene duplication.

TOP2A TOP2B

1.70e-052144210095062
Pubmed

mTOR inhibitors activate PERK signaling and favor viability of gastrointestinal neuroendocrine cell lines.

MTOR EIF2AK3

1.70e-052144228423496
Pubmed

Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.

TOP2A TOP2B

1.70e-052144214996935
Pubmed

Structural organization of the human TOP2A and TOP2B genes.

TOP2A TOP2B

1.70e-05214429795238
Pubmed

The distribution of DNA topoisomerase II isoforms in differentiated adult mouse tissues.

TOP2A TOP2B

1.70e-05214428241259
Pubmed

Dynamics of human DNA topoisomerases IIalpha and IIbeta in living cells.

TOP2A TOP2B

1.70e-052144211927602
Pubmed

Topoisomerase II binds importin alpha isoforms and exportin/CRM1 but does not shuttle between the nucleus and cytoplasm in proliferating cells.

TOP2A TOP2B

1.70e-052144217182034
Pubmed

Birth of two chimeric genes in the Hominidae lineage.

PMCHL1 PMCHL2

1.70e-052144211181993
Pubmed

Structure and expression of the variant melanin-concentrating hormone genes: only PMCHL1 is transcribed in the developing human brain and encodes a putative protein.

PMCHL1 PMCHL2

1.70e-052144211070051
Pubmed

Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons.

TOP2A TOP2B

1.70e-052144228700616
Pubmed

Predictors and mechanisms of epilepsy occurrence in cerebral gliomas: What to look for in clinicopathology.

TOP2A TOP2B

1.70e-052144228087392
Pubmed

Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint.

TOP2A TOP2B

1.70e-052144228472494
Pubmed

Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking.

MTOR RPTOR

1.70e-052144217301289
Pubmed

Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7.

MTOR FBXW7

1.70e-052144231278268
Pubmed

Association of immunophenotype with expression of topoisomerase II α and β in adult acute myeloid leukemia.

TOP2A TOP2B

1.70e-052144232218491
Pubmed

FBW7 Regulates the Autophagy Signal in Mesangial Cells Induced by High Glucose.

MTOR FBXW7

1.70e-052144231119177
Pubmed

Conditional Knockout of Raptor/mTORC1 Results in Dentin Malformation.

MTOR RPTOR

1.70e-052144230984011
Pubmed

Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2.

TOP2A TOP2B

1.70e-052144230169847
Pubmed

Hepatic peroxisomal β-oxidation suppresses lipophagy via RPTOR acetylation and MTOR activation.

MTOR RPTOR

1.70e-052144232687428
Pubmed

Temporal mTOR inhibition protects Fbxw7-deficient mice from radiation-induced tumor development.

MTOR FBXW7

1.70e-052144223454868
Pubmed

The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues.

TOP2A TOP2B

1.70e-05214429155056
Pubmed

A study of the topoisomerase II activity in HIV-1 replication using the ferrocene derivatives as probes.

TOP2A TOP2B

1.70e-052144216712776
Pubmed

Activity-independent targeting of mTOR to lysosomes in primary osteoclasts.

TCIRG1 MTOR

1.70e-052144228592812
Pubmed

Active heterodimers are formed from human DNA topoisomerase II alpha and II beta isoforms.

TOP2A TOP2B

1.70e-05214428710863
Pubmed

Distinct expression patterns for type II topoisomerases IIA and IIB in the early foetal human telencephalon.

TOP2A TOP2B

1.70e-052144226612825
Pubmed

Discrete localization of different DNA topoisomerases in HeLa and K562 cell nuclei and subnuclear fractions.

TOP2A TOP2B

1.70e-05214428299728
Pubmed

DNA-PKcs function regulated specifically by protein phosphatase 5.

PPP5C PRKDC

1.70e-052144214734805
Pubmed

Mitotic raptor promotes mTORC1 activity, G(2)/M cell cycle progression, and internal ribosome entry site-mediated mRNA translation.

MTOR RPTOR

1.70e-052144220439490
Pubmed

Molecular physiology of renal organic anion transporters.

SLCO4A1 SLCO3A1 SLC22A7

1.93e-0513144316403838
Pubmed

Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication.

PRKDC TOP2A TOP2B

3.05e-0515144312393188
Pubmed

Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.

SLCO3A1 ABCC6 SLC22A7

3.74e-0516144335307651
Pubmed

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.

IQGAP2 HUWE1 WDR3 FADS1 MTOR LPCAT3 TOP2A TOP2B TP53BP1

4.67e-05400144935013556
Pubmed

Assignment of the human pro-melanin-concentrating hormone gene (PMCH) to chromosome 12q23-q24 and two variant genes (PMCH1 and PMCHL2) to chromosome 5p14 and 5q12-q13.

PMCHL1 PMCHL2

5.09e-05314428188237
Pubmed

FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.

MTOR FBXW7

5.09e-053144218787170
Pubmed

Distribution and association of mTOR with its cofactors, raptor and rictor, in cumulus cells and oocytes during meiotic maturation in mice.

MTOR RPTOR

5.09e-053144223440873
Pubmed

Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis.

TOP2A TOP2B

5.09e-053144211136718
Pubmed

Expression profiling reveals transcriptional regulation by Fbxw7/mTOR pathway in radiation-induced mouse thymic lymphomas.

MTOR FBXW7

5.09e-053144226575021
Pubmed

mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition.

MTOR RPTOR

5.09e-053144225385646
Pubmed

mTOR has a developmental stage-specific role in mitochondrial fitness independent of conventional mTORC1 and mTORC2 and the kinase activity.

MTOR RPTOR

5.09e-053144228813526
Pubmed

mTOR Signaling in Growth, Metabolism, and Disease.

MTOR RPTOR

5.09e-053144228283069
Pubmed

Proteolytic degradation of topoisomerase II (Top2) enables the processing of Top2·DNA and Top2·RNA covalent complexes by tyrosyl-DNA-phosphodiesterase 2 (TDP2).

TOP2A TOP2B

5.09e-053144224808172
Pubmed

Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation.

MTOR RPTOR

5.09e-053144217656678
Pubmed

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.

MTOR RPTOR

5.09e-053144220008564
Pubmed

Identification of functional nuclear export sequences in human topoisomerase IIalpha and beta.

TOP2A TOP2B

5.09e-053144212821127
Pubmed

Lipid signalling drives proteolytic rewiring of mitochondria by YME1L.

MTOR YME1L1

5.09e-053144231695197
Pubmed

Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.

MTOR RPTOR

5.09e-053144222356909
Pubmed

mTORC1 directly phosphorylates and activates ERα upon estrogen stimulation.

MTOR RPTOR

5.09e-053144226522726
Pubmed

Leucine regulates autophagy via acetylation of the mTORC1 component raptor.

MTOR RPTOR

5.09e-053144232561715
Cytoband11q24.2

OR8D1 FOXRED1 OR10G7 OR8G5 OR10G8

1.72e-0663144511q24.2
CytobandEnsembl 112 genes in cytogenetic band chr11q24

OR8D1 FOXRED1 OR10G7 OR8G5 OR10G9 OR10G8

3.32e-051911446chr11q24
Cytoband19p13.1

MYO9B OR10H2 OR10H1

4.71e-0448144319p13.1
GeneFamilyOlfactory receptors, family 10

OR10H5 OR10G7 OR10A4 OR10H2 OR10H1 OR10G9 OR10G8

9.37e-08661037157
GeneFamilySolute carriers

SLC22A23 SLCO4A1 SLC38A5 SLCO3A1 SLC1A7 SLC22A7 SLC6A1 SLC5A11 SLC46A3 SLC16A4 SLC18A2 SLC26A11 SLC38A6

3.84e-0739510313752
GeneFamilyATP binding cassette subfamily A

ABCA10 ABCA6 ABCA5

6.24e-05141033805
GeneFamilyMTOR complex 1|MTOR complex 2

MTOR RPTOR

1.91e-04410321332
GeneFamilyTopoisomerases

TOP2A TOP2B

4.75e-04610321050
GeneFamilyFatty acid desaturases

FADS1 DEGS2

8.80e-0481032553
GeneFamilyTudor domain containing

LBR UHRF2 TP53BP1

1.21e-03371033780
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW2 FBXW7

1.71e-03111032559
GeneFamily5-hydroxytryptamine receptors, G protein-coupled

HTR1E HTR1F

2.41e-03131032170
GeneFamilyATP binding cassette subfamily C

CFTR ABCC6

2.41e-03131032807
GeneFamilyPotassium two pore domain channel subfamily K

KCNK16 KCNK2

3.22e-03151032277
GeneFamilyOlfactory receptors, family 9

OR9K2 OR9I1

7.52e-03231032156
GeneFamilyOlfactory receptors, family 13

OR13C3 OR13C4

7.52e-03231032162
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC38A5 ABCA10 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 AGTR1 CHRDL1

1.54e-081951449df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC38A5 ABCA10 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 AGTR1 CHRDL1

1.54e-0819514494243190ad291d56694e2155954dbaa879c9d3844
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

EYA4 ABCA10 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 UGT2B4

1.39e-0718114489ede19228ba5c0668a9c06c915510b95585216ef
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC38A5 ABCA10 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 CHRDL1

1.71e-0718614485473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC38A5 ABCA10 SLIT2 PIEZO2 HMCN1 ABCA6 AGTR1 CHRDL1

2.55e-07196144842e9828222a9663525d571633e8a454c30bfa7f8
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SLC38A5 PTGS1 SLC16A4 ABCA6 OR10H1 AGTR1 CHRDL1 TRAM2

2.97e-0720014483e0041c04e42a47257517dae8707a6454570c256
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC38A5 ABCC6 MFSD2A HMCN1 SLC16A4 CYYR1 DEGS2

1.09e-0616414476a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC38A5 ABCC6 MFSD2A HMCN1 SLC16A4 CYYR1 DEGS2

1.09e-061641447ec68954fc09b6850273b5e59caa6b09d02151097
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 CFTR ADTRP UST STAP1 SLIT2 ABCA5

1.23e-061671447edc5f04584b44f99ff9a62bbe0dab6fc044fb334
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 CFTR ADTRP UST STAP1 SLIT2 ABCA5

1.61e-0617414475f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 CFTR ADTRP UST STAP1 SLIT2 ABCA5

1.68e-06175144777c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 CFTR ADTRP UST STAP1 SLIT2 ABCA5

1.68e-06175144798947a226b5a2ac7091ff9d34243ea7736add973
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 CFTR ADTRP UST STAP1 SLIT2 ABCA5

1.74e-06176144725ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 CFTR ADTRP UST STAP1 SLIT2 ABCA5

1.74e-061761447c2c4306476989bc2fb30dab00250ef7915842f13
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 CFTR ADTRP UST STAP1 SLIT2 ABCA5

1.95e-061791447e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 CFTR ADTRP UST STAP1 SLIT2 ABCA5

2.10e-06181144730729f0364f719c044712a51453e22dc2c1a232b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 CFTR ADTRP UST STAP1 SLIT2 ABCA5

2.42e-0618514479438097e94219c1db922b8507e3a29106d32a923
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 CFTR ADTRP UST STAP1 SLIT2 ABCA5

2.51e-061861447a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 CFTR ADTRP UST STAP1 SLIT2 ABCA5

2.70e-061881447e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EYA4 IQGAP2 ADTRP GPR160 STAP1 GLS CNGA1

2.79e-061891447532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFTR TMC4 ABCC6 MFSD2A DUOX1 ATP8A1 AGBL1

2.89e-06190144727a1a86620fe9b5ee930d388b32352206485e6d0
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLCO3A1 UST RYR2 SLIT2 PIEZO2 FADS1 ABCA6

3.10e-061921447f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A5 ABCC6 MFSD2A HMCN1 SLC16A4 CYYR1 DEGS2

3.10e-0619214479ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLCO3A1 UST RYR2 SLIT2 PIEZO2 FADS1 ABCA6

3.10e-061921447ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A5 ABCC6 MFSD2A HMCN1 SLC16A4 CYYR1 DEGS2

3.10e-061921447a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A5 ABCC6 MFSD2A HMCN1 SLC16A4 CYYR1 DEGS2

3.10e-06192144766defad13bd8e79319741e43ddb056841710b1d7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBXO40 CFTR ADTRP STAP1 SLIT2 ABCA5

3.17e-0612414461fec6663cea40017438ead397b3bf8b3cdb67e58
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

ABCA10 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 AGTR1

3.43e-061951447aa0add081881d349099d12efca5cdee098038d4e
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC38A5 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 CHRDL1

3.55e-0619614479737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC38A5 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 CHRDL1

3.55e-061961447cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA10 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 CHRDL1

3.55e-0619614477d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellCOPD-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

SLC38A5 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 CHRDL1

3.67e-061971447d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|normal_Lung / Location, Cell class and cell subclass

SLC38A5 SLIT2 PIEZO2 HMCN1 ABCA6 AGTR1 CHRDL1

3.67e-0619714476c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

SLC22A23 ADTRP BCR STAP1 PIEZO2 SLC16A4 ABCA6

3.67e-0619714478545baf923ddf84c5ce9414a36d810603be52401
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC38A5 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 CHRDL1

3.67e-06197144713896ec65ccda0b928c91d41112dc01b480036b7
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLC38A5 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 CHRDL1

3.80e-061981447f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCellproximal-mesenchymal-Alveolar_Fibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC38A5 SLIT2 PIEZO2 HMCN1 ABCA6 UGT2B4 CHRDL1

3.92e-0619914477f4840ae6a888380feca722543e5e52783f3e35d
ToppCellproximal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC38A5 SLIT2 PIEZO2 HMCN1 ABCA6 UGT2B4 CHRDL1

3.92e-061991447301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCellproximal-mesenchymal-Alveolar_Fibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC38A5 SLIT2 PIEZO2 HMCN1 ABCA6 UGT2B4 CHRDL1

3.92e-0619914479a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCelldistal-mesenchymal-Alveolar_Fibroblast-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC38A5 SLIT2 PIEZO2 HMCN1 ABCA6 UGT2B4 CHRDL1

3.92e-061991447fb23ecce41e31e2cc01814e3c0add756f489561f
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLC38A5 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 CHRDL1

3.92e-06199144766a79732caf2f04c09b4d9832377aa01ca477677
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SLC38A5 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 CHRDL1

4.06e-0620014478c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SLC38A5 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 CHRDL1

4.06e-062001447aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC38A5 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 CHRDL1

4.06e-062001447a510deaada669e690329183e18df02870bd204b3
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SLC38A5 ABCA10 SLIT2 PIEZO2 HMCN1 ABCA6 CHRDL1

4.06e-0620014476e3d1ae0ef84d3075afa40129a41169996462672
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SLC38A5 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 CHRDL1

4.06e-062001447cb31cfcfa8e6d6cc610c4c22e97bc009dd8a9e7c
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC38A5 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 CHRDL1

4.06e-062001447dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CDH26 SLC22A23 ADTRP UST STAP1 SLIT2

7.51e-061441446cc11cce43d1af8ac63140d05faf215ae9a10cde1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 ADTRP UST STAP1 SLIT2 ABCA5

1.02e-0515214469391b46a441cf031665df1d142e3f65e98675eeb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFTR ADTRP UST STAP1 SLIT2 ABCA5

1.23e-051571446c17c5c01fcb65c453690c265ec4f300ecdfefd34
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXRED1 PANX1 CALHM6 ABCA6 TRAM2 TOP2A

1.32e-051591446999f30c7273ed77b34537621bcfcc7fc30121138
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BBS1 ADTRP UST STAP1 ABCA5 AGTR1

1.37e-051601446174a4ab27114efcc63be36929b80680be3c35c9b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 ADTRP UST STAP1 SLIT2 ABCA5

1.37e-0516014461e210e526ea4d84fc58a798a26c0929bcb69fd89
ToppCellFetal_29-31_weeks-Immune-mast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HTR1F IQGAP2 MFSD2B PTGS1 STAP1 SLC18A2

1.52e-05163144603b2ec226adffba3ce893f3d12e549c841e662fd
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK|Cerebellum / BrainAtlas - Mouse McCarroll V32

SLC38A5 ABCC6 GPR160 HMCN1 SLC16A4 CYYR1

1.63e-0516514467d319a112b9062efee428bef6f4534d2ce782e04
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC38A5 MFSD2A HMCN1 SLC16A4 CYYR1 DEGS2

1.69e-05166144627af6c906cff1d40d134f0386db7708869691121
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HTR1F TMC4 RYR2 SLC6A1 SLIT2 HMCN1

1.99e-051711446a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCellImmune-mast_cell|World / Lineage, Cell type, age group and donor

HTR1F IQGAP2 MFSD2B PTGS1 STAP1 SLC18A2

2.06e-0517214466e8e0aac5a20dbc789bf8c6916833bb8709a411a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9B SLCO3A1 PIEZO2 NOP14 AGTR1 CHRDL1

2.27e-05175144612f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 ADTRP UST STAP1 SLIT2 ABCA5

2.27e-0517514461d8da48236549c01381f777ce5b2937f9f86acc2
ToppCellCOVID-19-kidney-CD-IC-A|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFTR ADTRP UST STAP1 SLIT2 ABCA5

2.35e-05176144645028197364c64e93e3ffe86aff773d47a477d49
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFTR ADTRP UST STAP1 SLIT2 ABCA5

2.42e-0517714468e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EYA4 SLC22A23 ADTRP STAP1 SLIT2 CNGA1

2.42e-051771446f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK11 SLC6A1 SLIT2 PIEZO2 KCNK2 AGBL1

2.58e-051791446d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCellrenal_papilla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

EYA4 SLCO4A1 SLCO3A1 PTGS1 KCNK2 CNGA1

2.66e-05180144649829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCellCOVID-19-kidney-CD-IC-A|kidney / Disease (COVID-19 only), tissue and cell type

CFTR ADTRP UST STAP1 SLIT2 ABCA5

2.92e-0518314465c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

HTR1F DOCK11 SLIT2 HMCN1 ABCA6 TRAM2

3.01e-05184144667164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFTR ADTRP UST STAP1 SLIT2 ABCA5

3.30e-0518714467b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCellwk_15-18-Hematologic-Myeloid-Basophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EFL1 PCNX3 MYO9B LBR STAP1 SLC18A2

3.40e-0518814463638d85452de15a060146628fbbad9d2a36feb13
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EYA4 SLC22A23 ADTRP GPR160 STAP1 SLIT2

3.40e-05188144658ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC22A23 SLIT2 PIEZO2 HMCN1 ABCA6 AGTR1

3.50e-051891446203c80030df08ae112f9ae4043709f455d87ce89
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

ABCA10 SLIT2 PIEZO2 ABCA6 CHRDL1 TRAM2

3.60e-0519014467dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellmegakaryocytic-CD34+_Megakaryoblast|World / Lineage and Cell class

CDH26 PTGS1 RYR2 PIEZO2 FADS1 SLC18A2

3.60e-0519014461d19b2bd55789bf13e1386332f46c605973d6f8e
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLCO3A1 UST RYR2 SLIT2 PIEZO2 FADS1

3.60e-05190144645df8fee00f8949937863159d7aa042e72748d9b
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

ABCA10 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6

3.60e-0519014463a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

CFTR ABCC6 MFSD2A DUOX1 ATP8A1 AGBL1

3.71e-051911446276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|lung / Disease (COVID-19 only), tissue and cell type

IQGAP2 DOCK11 MYO9B ADTRP PIK3R5 SLC38A6

3.71e-051911446dab953682b8c9ed680a799161f837f792a7e4f33
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA10 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6

3.71e-0519114466688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

IQGAP2 DOCK11 MYO9B ADTRP PIK3R5 SLC38A6

3.82e-051921446bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EYA4 IQGAP2 PTGS1 GPR160 GLS CNGA1

3.82e-0519214460bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

CFTR ABCC6 MFSD2A DUOX1 ATP8A1 AGBL1

3.82e-051921446499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA10 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6

3.82e-05192144699ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLCO3A1 UST RYR2 SLIT2 PIEZO2 FADS1

3.82e-051921446162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

SLC22A23 ABCC6 MFSD2A DUOX1 ATP8A1 AGBL1

3.82e-051921446efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TM6SF2 ABCA10 SLIT2 PIEZO2 ABCA6 CHRDL1

3.82e-051921446c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLCO3A1 UST RYR2 SLIT2 PIEZO2 ABCA6

3.82e-051921446deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 UGT2B4

3.93e-05193144699525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

RYR2 SLIT2 PIEZO2 HMCN1 ABCA6 UGT2B4

3.93e-051931446ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

SLC22A23 CFTR MFSD2A DUOX1 ATP8A1 AGBL1

3.93e-051931446738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EYA4 IQGAP2 RAB11FIP2 PTGS1 GPR160 CNGA1

4.05e-05194144604bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EYA4 PTGS1 GPR160 SLC16A4 GLS CNGA1

4.05e-0519414464d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCellControl-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

SLC38A5 RYR2 SLIT2 HMCN1 ABCA6 CHRDL1

4.05e-0519414463c2266772c5b56e8e02a461e5193e29588028ee9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EYA4 IQGAP2 RAB11FIP2 PTGS1 GPR160 CNGA1

4.05e-05194144669bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell(4)_Endothelial_cells-(4)_Lymph_vessel|(4)_Endothelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

WFS1 CALHM6 PIEZO2 CHRDL1 ACKR2 DEGS2

4.05e-0519414469735b86d3b2480a0b34d8aab8e7bd609d83c2454
ToppCellControl-Stromal-Myofibroblast|Control / Disease state, Lineage and Cell class

SLC38A5 RYR2 SLIT2 HMCN1 ABCA6 CHRDL1

4.16e-051951446ffcf76cd72e43d8cf1058a49c76e0956065038bc
ToppCellIPF-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

WFS1 SLC22A23 PIEZO2 HMCN1 CHRDL1 ACKR2

4.16e-051951446de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

ABCA10 RYR2 SLIT2 PIEZO2 HMCN1 ABCA6

4.16e-051951446603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPR160 MFSD2A DUOX1 FADS1 ATP8A1 GLS

4.16e-051951446d9694db6bf239636d1335016878c98f6ee2eb0eb
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EYA4 SLIT2 PIEZO2 HMCN1 ABCA6 OR10A4

4.16e-051951446f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCell-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

RYR2 CD247 PIEZO2 ABCA6 SLC18A2 CHRDL1

4.16e-051951446e5b0afbea85575851cf9eb50a9ac42c67bbf3d7c
DrugNSC115907

FOXRED1 TCIRG1 PTGS1 DUOX1 MTOR SLC18A2 GLS CHRDL1 DEGS2 EIF2AK3 TOP2B

8.67e-0726614111CID000005102
Drug3-O-caffeoyl-D-quinic acid

BCR SLC5A11 MTOR UGT2B4 CHRDL1

4.69e-06401415CID000009476
Drugcompound 31

HTR1E HTR1F SLC38A5 LBR HTR3D

6.00e-06421415CID005288687
DrugNiflumic Acid

CFTR PANX1 SLC6A1 KCNK2 EIF2AK3

6.00e-06421415ctd:D009544
Drugsodium

CFTR SLCO4A1 SLC38A5 SLCO3A1 TCIRG1 HUWE1 PTGS1 SLC1A7 RYR2 SLC6A1 SLC5A11 MTOR SLC18A2 GLS AGTR1 KCNK2 SLC26A11 YME1L1

2.23e-0594414118CID000000923
Drugamphimedine

CFTR TOP2B

3.81e-0521412CID000100819
DrugDexrazoxane

TOP2A TOP2B

3.81e-0521412DB00380
Drugoxoaporphine

CFTR TOP2B

3.81e-0521412CID000326183
Drugeriochrome cyanin

CFTR BCR

3.81e-0521412CID000075762
DrugF14512

TOP2A TOP2B

3.81e-0521412ctd:C534191
DrugDaunorubicin

TOP2A TOP2B

3.81e-0521412DB00694
Drugracemosol

CFTR PTGS1

3.81e-0521412CID000624971
Drugterbium chloride

CHRDL1 TOP2B

3.81e-0521412CID000061458
Drugradicicol

FOXRED1 BCR PTGS1 PPP5C MTOR EIF2AK3 TOP2B FBXW7

4.00e-052031418CID000005033
Diseaselevel of Phosphatidylinositol (16:0_18:1) in blood serum

TMC4 FADS1 RRN3

2.00e-05121353OBA_2045152
DiseaseMassive Hepatic Necrosis

PANX1 PRKDC

2.08e-0521352C0001364
DiseaseB cell deficiency (implicated_via_orthology)

TOP2A TOP2B

2.08e-0521352DOID:2115 (implicated_via_orthology)
Diseaselysophosphatidylcholine 20:3 measurement

TM6SF2 FADS1 RRN3 ZNF91

3.37e-05401354EFO_0010362
DiseaseColorectal Neoplasms

EYA4 CFTR ARID1A ABCA10 ABCC6 FADS1 ABCA6 ABCA5

4.32e-052771358C0009404
DiseaseColorectal Carcinoma

EYA4 CFTR ARID1A ABCA10 ABCC6 SLC1A7 FADS1 ABCA6 ABCA5 UHRF2 PIK3R5 FBXW7

9.64e-0570213512C0009402
DiseaseAdenoid Cystic Carcinoma

ARID1A ERBIN PRKDC TOP2A FBXW7

9.89e-051001355C0010606
Diseasetriglycerides in large VLDL measurement

ARID1A TM6SF2 FADS1 TP53BP1

1.28e-04561354EFO_0022178
Diseasetriglycerides in VLDL measurement

ARID1A TM6SF2 FADS1 TP53BP1

1.57e-04591354EFO_0022326
Diseasecholesteryl ester measurement

ARID1A TM6SF2 ABCA10 FADS1 ABCA6 RRN3 TP53BP1

1.88e-042571357EFO_0010351
Diseasetotal lipids in very large VLDL measurement

ARID1A TM6SF2 FADS1 TP53BP1

1.90e-04621354EFO_0022313
Diseasephospholipids in very large VLDL measurement

ARID1A TM6SF2 FADS1 TP53BP1

1.90e-04621354EFO_0022299
Diseasecholesterol in very large VLDL measurement

ARID1A TM6SF2 FADS1 TP53BP1

2.29e-04651354EFO_0022230
Diseaseacute lymphoblastic leukemia

OR2C3 SLCO3A1 RYR2 AGBL1

2.42e-04661354EFO_0000220
Diseasetotal lipids in large VLDL

ARID1A TM6SF2 FADS1 TP53BP1

2.57e-04671354EFO_0022175
Diseasefree cholesterol in large VLDL measurement

ARID1A TM6SF2 FADS1 TP53BP1

2.72e-04681354EFO_0022265
Disease1-stearoyl-GPC (18:0) measurement

MFSD2A FADS1

3.08e-0461352EFO_0800217
Disease1-stearoyl-2-dihomo-linolenoyl-GPC (18:0/20:3n3 or 6) measurement

FADS1 RRN3

3.08e-0461352EFO_0800434
Disease1-arachidonoyl-GPI (20:4) measurement

TMC4 FADS1

4.30e-0471352EFO_0800256
Disease1-linoleoyl-GPI (18:2) measurement

TMC4 FADS1

4.30e-0471352EFO_0800266
Disease1-palmitoyl-GPE (16:0) measurement

MFSD2A TP53BP1

4.30e-0471352EFO_0800245
Diseasestromal cell-derived factor 1 measurement

ABCA6 ABCA5

4.30e-0471352EFO_0020756
Disease1-palmitoyl-2-linoleoyl-GPI (16:0/18:2) measurement

TMC4 FADS1

4.30e-0471352EFO_0800609
Diseaselevel of Phosphatidylinositol (16:0_18:2) in blood serum

TMC4 FADS1

5.71e-0481352OBA_2045153
Diseasephospholipids:total lipids ratio

ARID1A TM6SF2 FADS1 ABCA6 RRN3 TP53BP1

6.39e-042271356EFO_0020946
Diseaserenovascular hypertension (implicated_via_orthology)

PTGS1 AGTR1

7.32e-0491352DOID:1591 (implicated_via_orthology)
Diseaselongitudinal alcohol consumption measurement

SPATA31C1 SLC6A1

7.32e-0491352EFO_0007645
Disease1-palmitoyl-2-oleoyl-GPI (16:0/18:1) measurement

TMC4 FADS1

7.32e-0491352EFO_0800439
Disease1-palmitoyl-2-arachidonoyl-GPI (16:0/20:4) measurement

TMC4 FADS1

7.32e-0491352EFO_0800412
Diseaseoleoyl-arachidonoyl-glycerol (18:1/20:4) [1] measurement

TM6SF2 FADS1

9.13e-04101352EFO_0800507
Disease1-stearoyl-2-oleoyl-GPI (18:0/18:1) measurement

TMC4 FADS1

9.13e-04101352EFO_0800469
Diseaseconcentration of large LDL particles measurement

TM6SF2 ABCA10 ABCA6

1.08e-03441353EFO_0022160
Diseasecholesterol in medium VLDL measurement

TM6SF2 ABCA10 ABCA6

1.08e-03441353EFO_0022225
Diseaseautosomal recessive polycystic kidney disease (biomarker_via_orthology)

CFTR PANX1

1.11e-03111352DOID:0110861 (biomarker_via_orthology)
Diseasemiddle temporal gyrus volume measurement

OR13C3 OR13C4

1.11e-03111352EFO_0010316
Diseasevery low density lipoprotein cholesterol measurement

ARID1A TM6SF2 ABCA10 FADS1 ABCA6 TP53BP1

1.29e-032601356EFO_0008317
Diseasefree cholesterol in small VLDL measurement

TM6SF2 ABCA10 ABCA6

1.31e-03471353EFO_0022272
Diseasefree cholesterol in medium VLDL measurement

TM6SF2 ABCA10 ABCA6

1.31e-03471353EFO_0022269
Diseaselinoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement

TM6SF2 FADS1

1.33e-03121352EFO_0800500
Diseasephosphatidylcholine 34:4 measurement

TM6SF2 FADS1

1.33e-03121352EFO_0010378
Disease1-myristoyl-2-arachidonoyl-GPC (14:0/20:4) measurement

TM6SF2 FADS1

1.33e-03121352EFO_0800453
Diseaseacute myeloid leukemia (implicated_via_orthology)

TOP2A TOP2B

1.33e-03121352DOID:9119 (implicated_via_orthology)
Diseaseglycerophospholipid measurement

TMC4 FADS1 CYYR1

1.48e-03491353EFO_0007630
Diseasephosphatidylcholine 40:7 measurement

FADS1 RRN3

1.57e-03131352EFO_0021477
Disease1-stearoyl-2-linoleoyl-GPI (18:0/18:2) measurement

TMC4 FADS1

1.57e-03131352EFO_0800413
Diseasephospholipids in very small VLDL measurement

ABCA10 ABCA6 TP53BP1

1.66e-03511353EFO_0022300
Diseasephospholipids in IDL measurement

TM6SF2 ABCA10 ABCA6

1.76e-03521353EFO_0022164
Disease1-stearoyl-2-dihomo-linolenoyl-GPI (18:0/20:3n3 or 6) measurement

TMC4 FADS1

1.82e-03141352EFO_0022085
Diseasediacylglycerol 38:4 measurement

TMC4 FADS1

1.82e-03141352EFO_0020066
DiseasePrecursor T-Cell Lymphoblastic Leukemia-Lymphoma

BCR MTOR FBXW7

1.86e-03531353C1961099
Diseasecholesterol in small VLDL measurement

TM6SF2 ABCA10 ABCA6

1.86e-03531353EFO_0022228
Diseasetriglycerides in medium VLDL measurement

ARID1A TM6SF2 TP53BP1

2.07e-03551353EFO_0022155
Diseasehealth study participation

SLC22A23 SLC5A11 NOP14 RPTOR TANGO6

2.07e-031951355EFO_0010130
Diseaseliver volume

ARID1A TP53BP1

2.10e-03151352EFO_0600048
Diseaseoleoyl-arachidonoyl-glycerol (18:1/20:4) [2] measurement

TM6SF2 FADS1

2.10e-03151352EFO_0800508
Diseaseglycerate measurement

HMCN1 ACKR2

2.10e-03151352EFO_0021029
Diseasephosphatidate measurement

TMC4 FADS1

2.10e-03151352EFO_0020047
Diseasetriglycerides in very large VLDL measurement

ARID1A TM6SF2 TP53BP1

2.17e-03561353EFO_0022325
Diseasefree cholesterol to total lipids in large HDL percentage

FADS1 ABCA6 RRN3

2.17e-03561353EFO_0022279
Diseasefree cholesterol to total lipids in medium VLDL percentage

ABCA6 RRN3 TP53BP1

2.29e-03571353EFO_0022284
Disease1-stearoyl-2-arachidonoyl-GPI (18:0/20:4) measurement

TMC4 FADS1

2.39e-03161352EFO_0800184
Diseaseamygdala volume change measurement

PKD1L1 SPATA31C1

2.39e-03161352EFO_0021490
Diseasecholesterol in IDL measurement

TM6SF2 ABCA6 RRN3

2.40e-03581353EFO_0021899
Diseasetriglycerides to total lipids in small LDL percentage

ABCA6 RRN3 TP53BP1

2.53e-03591353EFO_0022337
Diseasephospholipids in small VLDL measurement

TM6SF2 ABCA6 TP53BP1

2.65e-03601353EFO_0022146
Diseasetotal lipids in VLDL measurement

ARID1A TM6SF2 TP53BP1

2.65e-03601353EFO_0022314
Diseasecholesterol to total lipids in IDL percentage

ARID1A RRN3 TP53BP1

2.65e-03601353EFO_0022233
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

ARID1A FADS1 ABCA6 RRN3 TP53BP1 TANGO6

2.77e-033031356EFO_0004612, EFO_0020945
Diseasefree cholesterol in IDL measurement

TM6SF2 ABCA6 RRN3

2.78e-03611353EFO_0022181
Diseasefree cholesterol in very large VLDL measurement

ARID1A FADS1 TP53BP1

2.78e-03611353EFO_0022274
Diseasephospholipids in large VLDL measurement

ARID1A TM6SF2 TP53BP1

2.91e-03621353EFO_0022169
Diseasetriglycerides in medium LDL measurement

ARID1A FADS1 TP53BP1

2.91e-03621353EFO_0022322
Diseasephosphatidylcholine 36:4 measurement

FADS1 UGT2B4

3.03e-03181352EFO_0010382
Diseaselevel of Phosphatidylinositol (18:0_18:1) in blood serum

TMC4 FADS1

3.03e-03181352OBA_2045155
Diseasetriglycerides to total lipids in IDL percentage

ABCA6 RRN3 TP53BP1

3.04e-03631353EFO_0022329
Diseasetriglycerides to total lipids in medium VLDL percentage

ABCA6 RRN3 TP53BP1

3.04e-03631353EFO_0022335
Diseasecholesterol to total lipids in medium VLDL percentage

ABCA6 RRN3 TP53BP1

3.04e-03631353EFO_0022239
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

ARID1A TM6SF2 FADS1 ABCA6 TP53BP1

3.16e-032151355EFO_0008317, EFO_0008591
Diseasevery low density lipoprotein particle size measurement

ARID1A TM6SF2 FADS1 TP53BP1

3.31e-031331354EFO_0008594
Diseasecholesterol in large VLDL measurement

ARID1A TM6SF2 TP53BP1

3.33e-03651353EFO_0021902
Diseasepolycystic kidney disease (biomarker_via_orthology)

PTGS1 MTOR

3.38e-03191352DOID:0080322 (biomarker_via_orthology)
Diseasediacylglycerol 38:5 measurement

TM6SF2 FADS1

3.38e-03191352EFO_0020067
Diseasediacylglycerol 38:3 measurement

TMC4 FADS1

3.38e-03191352EFO_0020065
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

ARID1A TM6SF2 FADS1 ABCA6 TP53BP1

3.49e-032201355EFO_0004529, EFO_0008317
Diseaseviral load

TMC4 TMEM230 CD247 CYYR1

3.59e-031361354EFO_0010125
Diseasehearing loss

EYA4 IQGAP2 SLC22A7

3.62e-03671353EFO_0004238
Diseaseradiation-induced disorder

SLIT2 AGBL1 SLC38A6

3.62e-03671353EFO_0009565
Diseasecholesterol to total lipids in very small VLDL percentage

ABCA6 RRN3 TP53BP1

3.62e-03671353EFO_0022245
Diseasecorneal hysteresis

ABCA10 ABCA6

3.74e-03201352EFO_0010066
DiseaseSevere Combined Immunodeficiency

CD247 PRKDC

3.74e-03201352C0085110
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

ARID1A TM6SF2 FADS1 RRN3 TP53BP1

3.76e-032241355EFO_0004530, EFO_0008317
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

ARID1A TM6SF2 FADS1 ABCA6 TP53BP1

3.76e-032241355EFO_0004574, EFO_0008317
Diseasetriglycerides to phosphoglycerides ratio

ARID1A RRN3 TP53BP1

3.78e-03681353EFO_0022327
Diseasecholesteryl ester measurement, very low density lipoprotein cholesterol measurement

ARID1A TM6SF2 FADS1 ABCA6 TP53BP1

3.83e-032251355EFO_0008317, EFO_0010351
Diseasetriglycerides to total lipids in very small VLDL percentage

ABCA6 RRN3 TP53BP1

3.94e-03691353EFO_0022341
Diseaselevel of Phosphatidylcholine (18:1_20:4) in blood serum

TM6SF2 FADS1

4.12e-03211352OBA_2045104
Diseaselevel of Phosphatidylcholine (16:0_20:4) in blood serum

TM6SF2 FADS1

4.12e-03211352OBA_2045076
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

ARID1A TM6SF2 FADS1 ABCA6 TP53BP1

4.13e-032291355EFO_0004639, EFO_0008317
Diseasecholesteryl esters to total lipids in very small VLDL percentage

ABCA6 RRN3 TP53BP1

4.27e-03711353EFO_0022259
Diseasetriglycerides to total lipids in small HDL percentage

ARID1A RRN3 TP53BP1

4.44e-03721353EFO_0022336

Protein segments in the cluster

PeptideGeneStartEntry
IYPLLGCLISFIKIS

ABCA5

1176

Q8WWZ7
LLLIFISIAGILYKF

ABHD13

46

Q7L211
KVFLPVFYSLIFVLG

ACKR2

46

O00590
FIPGFIGSLKQLTYL

ERBIN

221

Q96RT1
LLVKFFPLLLLYPLT

ADCK2

106

Q7Z695
FVVFLSVLPYALIKG

CFTR

316

P13569
DIFSLGLILFELLYP

EIF2AK3

1006

Q9NZJ5
ALVDIPLYFLILFSI

ABCA10

981

Q8WWZ4
TFGAFYIPLALILIL

HTR1F

186

P30939
GTLKLYFRELPEPLF

BCR

1126

P11274
ILGFLFPFLIILTSY

AGTR1

201

P30556
KIFVLGPKYSPLEFL

EFL1

521

Q7Z2Z2
LLLALYFDKILPYGD

ABCA6

411

Q8N139
LVPSYTLLGFKTFLE

ABCA6

1161

Q8N139
PFFIKELIVGLSIYT

HTR1E

306

P28566
PLFTYGLIKLAFLSS

CASTOR2

21

A6NHX0
VYPVFAKLSLLGLAA

ADTRP

181

Q96IZ2
FLYAEIGLILIFCLP

BCAP29

11

Q9UHQ4
PLLATEFRGLALKYL

DCLRE1B

491

Q9H816
LFIPVASLLLDVVYK

ATP8A1

1056

Q9Y2Q0
YDILLPLFRLLAKVG

AGBL1

71

Q96MI9
PVLEKILFGVFLAIY

OR5M10

21

Q6IEU7
YFTRIIAFLLKLAVP

GPR107

506

Q5VW38
IKQGLLPSLEDLLFY

GLS

131

O94925
FLIQVLFYLLPIGKV

LBR

266

Q14739
LLGFTDYPKLQIPLF

OR5D14

16

Q8NGL3
DYPKLQIPLFLVFLL

OR5D14

21

Q8NGL3
AELQLPLFLLFLGIY

OR8D1

21

Q8WZ84
LSQLPGLLELLVEYF

ARID1A

1706

O14497
RGIGYLKLICFLIPF

ANKAR

311

Q7Z5J8
IFFLVPAIIYGGDKL

DUOX1

1251

Q9NRD9
PKLEIPLFLVFLSFY

OR9I1

21

Q8NGQ6
PLFLVFLSFYLVTLL

OR9I1

26

Q8NGQ6
PELHILLFLLFLFVY

OR9K2

46

Q8NGE7
SELQLPLFLVFLGIY

OR8G5

56

Q8NG78
GNKFGVLLFLYSVLL

MINDY3

176

Q9H8M7
LDAPLFGIFLVVYVL

OR10G7

21

Q8NGN6
LLSYAFIVAAILKIP

OR10H5

216

Q8NGA6
LLSYAFIVADILKIP

OR10H2

216

O60403
EFILLGLSGYPKLEI

OR13C4

11

Q8NGS5
GLSGYPKLEIIFFAL

OR13C4

16

Q8NGS5
LLIIPFTFLTKLLPY

OR52N4

156

Q8NGI2
GVLLPKLVLLFVYAD

CYYR1

11

Q96J86
VFYALLGIPLNVIFL

KCNK16

126

Q96T55
KIFCIIYALLGIPLF

KCNK2

171

O95069
LSVFIPPYFAEKIIL

BEND2

336

Q8NDZ0
SLVAFLGYLLLLKGF

PCNX3

801

Q9H6A9
LDPLLIFFSYGLIGK

OR51S1

216

Q8NGJ8
SIIPALKRLSLGLFY

LPCAT3

226

Q6P1A2
LTELPKDSFEGLLYL

LRRC37B

591

Q96QE4
PPYLKLVISFLFISA

MFSD2B

281

A6NFX1
LDAPLFGVFLVVYVL

OR10G8

21

Q8NGN5
YLASFVFVVLPLGLI

OR2C3

201

Q8N628
HKFFPYILLLFAILL

PANX1

106

Q96RD7
LSGYFLQLKFDPELL

PTGS1

351

P23219
LIYLKITGLLFPTSD

NOP14

546

P78316
FLEGFYEIIPKRLIS

HUWE1

4226

Q7Z6Z7
IKIALEISLPGSFIY

HMCN1

126

Q96RW7
LFILFPFLLILGSYV

OR10A4

206

Q9H209
PLDVNYLLFLIILGK

GPR160

21

Q9UJ42
PYIKLITGFLFTSLA

MFSD2A

306

Q8NA29
LAKVLLYSLGGAFPI

EYA4

556

O95677
LLGLAFLEYFPVELI

FASTKD5

476

Q7L8L6
LPLLSVKFLTRLYEA

KLHL28

226

Q9NXS3
AKIAQLYLPFVGLLL

DOCK11

1161

Q5JSL3
ILPLLYFFITKKNPI

SLC1A7

311

O00341
KYIFSLLFFLLLEGG

CHRDL1

11

Q9BU40
QLPLKRELFGFKSYL

CCDC18

401

Q5T9S5
YGLVFLLVPALALFL

CALHM6

51

Q5R3K3
LLDPKLCYLLDGILF

CD247

26

P20963
ISLLPKELALYVLSF

FBXW7

281

Q969H0
LSPFLFTRFYLGEKI

FOXRED1

466

Q96CU9
LKPVVYLLASSFLGL

DEGS2

206

Q6QHC5
FFLTYVPLLGLKAFL

FADS1

306

O60427
LPLEILKYIAGFLDS

FBXO40

576

Q9UH90
YFLTLLGKHELVPVL

MARVELD1

76

Q9BSK0
LVIKPYLALEGSVAF

PMCHL1

21

Q16048
LVIKPYLALEGSVAF

PMCHL2

21

Q9BQD1
ALLFLLRCYFVLEPK

CDH26

631

Q8IXH8
KYLRFLLGLPVGSTF

CCDC168

6621

Q8NDH2
FLKLLPLELSFYLLK

FBXW2

56

Q9UKT8
ALYSLPRAFFKVPLL

BBS1

526

Q8NFJ9
LFGAVELPSKLLVYL

SLC22A7

381

Q9Y694
FLFVPLIKLFYTLLI

RYR2

1816

Q92736
GILLFLFTLKCVYLP

PKD1L1

2616

Q8TDX9
LFLYSVPGYLVKKIL

OTOF

1981

Q9HC10
LDAPLFGIFLVVYVL

OR10G9

21

Q8NGN4
LLSYAFIVAAILKIP

OR10H1

216

Q9Y4A9
EFLLLGLSGYPKIEI

OR13C3

41

Q8NGS6
VILAPFFNPIIYSLK

OR6K6

306

Q8NGW6
VALGGEFKLYLPQLI

MTOR

1061

P42345
EIPILIIEGFLLFNY

NMRK1

91

Q9NWW6
IIEGFLLFNYKPLDT

NMRK1

96

Q9NWW6
YIGSFLARAKFIPLI

RRN3

406

Q9NYV6
YFLTLIFAGVPLFLL

SLC6A1

86

P30531
VTFVPGLYKIFDEIL

TOP2B

96

Q02880
SPELKSYALGVLFLL

SLCO3A1

566

Q9UIG8
FTVPKLLSLFLEFIG

ABCC6

326

O95255
SYLFIIKSELPLVIG

SLC38A5

141

Q8WUX1
IAKFSLLVGLIFGYL

SLC22A23

231

A1A5C7
ALSLYLFKLGIAPQI

IQGAP2

151

Q13576
PVLEKILFGVFLAIY

OR5M1

21

Q8NGP8
EVILTLFGFKLLYPD

PPP5C

281

P53041
PLETLALTYGFLEKV

PRAMEF22

296

A3QJZ6
LIYILFFLGDPVKEC

SLC46A3

211

Q7Z3Q1
LIFIFPGLFYLKLSR

SLC38A6

406

Q8IZM9
PGDIAVLVLYFLFVL

SLC5A11

26

Q8WWX8
TLVFALGLFFLLLPY

SPATA31C1

31

P0DKV0
TGLYPELFTLLLKLV

MROH2B

1156

Q7Z745
FILLPGVTEFYLLAA

OR6C6

101

A6NF89
LALSVGIFPYVLKLL

RPTOR

466

Q8N122
GLLYKVLGVLFFAIA

SLCO4A1

671

Q96BD0
LLLIYSEKIPSVLFL

SERPINA12

391

Q8IW75
GILIAIDALSFYLPL

HTR3D

241

Q70Z44
VLSLIPTDLLYFKLG

CNGA1

246

P29973
ILQTLLDLFFPGYSK

UHRF2

786

Q96PU4
LLLLERFLPHYFKGV

UST

291

Q9Y2C2
FSLGLAIFKPDLITY

ZNF727

41

A8MUV8
LPFLKNTVILLYPFA

UNC50

216

Q53HI1
IPDEYLLSLKFLFGS

ZSWIM7

26

Q19AV6
GLTFLLAPFTKFLID

SLC16A4

156

O15374
EKGTYDLLTPLALLF

PIK3R5

71

Q8WYR1
RLGFLLDFISYPVIK

SLC26A11

141

Q86WA9
FGELLAELLKIPFVY

UGT2B4

156

P06133
GPKDLVTILFYIFIT

TRAM2

71

Q15035
LLPLLNTVKFLLLFY

TMC4

551

Q7Z404
ITALPLYFEGFLLIK

STAP1

21

Q9ULZ2
YFLLFGGDLLLKPIK

PIEZO2

1326

Q9H5I5
LPVLGVLFLLYCFTK

TANGO6

476

Q9C0B7
VLELPYLGSAVSLFL

SERPINE3

246

A8MV23
QLFPELLFLGTAKLY

SLIT2

116

O94813
LLIQGSPEKYILFLI

RAB11FIP2

71

Q7L804
KFKYAVLFLLGLFVL

SEC11A

161

P67812
PLPLNKTLFLGYAFL

TP53BP1

1721

Q12888
LLVPGLIKDVLYEFR

IGSF9

681

Q9P2J2
KSIELFYKFVPLLPG

PRKDC

1186

P78527
LLFGIYGLLKNPFLS

YME1L1

301

Q96TA2
TFVPGLYKIFDEILV

TOP2A

76

P11388
FLGIALSKPDLITYL

ZNF91

51

Q05481
PADLALVIYLILAGF

TM6SF2

216

Q9BZW4
LKFFLSLYGHKLPVI

WDR3

581

Q9UNX4
VLYEFVGKTAPFLVL

SLC18A2

241

Q05940
IPYKAIALATVLFLI

TMEM230

41

Q96A57
LLELFIFLYKGVLLP

TMEM216

36

Q9P0N5
WGYKILFLDVLFPLV

UGGT1

1336

Q9NYU2
LPELTFLLGLFGYLV

TCIRG1

571

Q13488
IGYFLFLFALPILVA

WFS1

561

O76024
CIILKGLFEVLDLYP

KCNH8

641

Q96L42
SILVAINPFKFLPIY

MYO9B

181

Q13459