Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

KMT2C KMT2B KMT2A ASH2L

1.22e-0620824GO:0042800
GeneOntologyMolecularFunctionzinc ion binding

MSRB2 POLR3K KMT2B TRIM73 TLL1 KMT2A ZMYM1 TRIM29 RNF217 USP3 NOS1 ZMYM4 NR1D2 TRIM74 MPI

2.99e-068918215GO:0008270
GeneOntologyMolecularFunctionhistone H3K4 monomethyltransferase activity

KMT2C KMT2B KMT2A

3.68e-068823GO:0140945
GeneOntologyMolecularFunctionhistone modifying activity

DCAF1 KMT2C KMT2B BRPF1 KMT2A SMYD5 USP3 ASH2L

4.55e-06229828GO:0140993
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

KMT2C KMT2B KMT2A

7.85e-0610823GO:0140999
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

KMT2C KMT2B KMT2A SMYD5 ASH2L

8.79e-0668825GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

KMT2C KMT2B KMT2A SMYD5 ASH2L

9.44e-0669825GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

KMT2C KMT2B KMT2A SMYD5 ASH2L

1.09e-0571825GO:0042054
GeneOntologyMolecularFunctionextracellular matrix structural constituent

HMCN1 TNC MATN2 LAMB1 LTBP1 PRG4 MUC5AC

1.23e-05188827GO:0005201
GeneOntologyMolecularFunctioncargo receptor activity

LRP1 LRP2 PRG4 EGFEM1P SORL1

2.62e-0585825GO:0038024
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

KMT2C KMT2B KMT2A ASH2L

3.16e-0544824GO:0140938
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP2 SORL1

3.60e-0516823GO:0005041
GeneOntologyMolecularFunctioncalcium ion binding

SCUBE1 HMCN1 SUSD1 MATN2 TLL1 LRP1 LRP2 LTBP1 LTBP3 EGFEM1P NOTCH2 PROS1

5.29e-057498212GO:0005509
GeneOntologyMolecularFunctionprotein methyltransferase activity

KMT2C KMT2B KMT2A SMYD5 ASH2L

6.59e-05103825GO:0008276
GeneOntologyMolecularFunctionN-methyltransferase activity

KMT2C KMT2B KMT2A SMYD5 ASH2L

7.23e-05105825GO:0008170
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 LRP2 SORL1

8.42e-0521823GO:0030228
GeneOntologyMolecularFunctiontransition metal ion binding

MSRB2 POLR3K KMT2B TRIM73 TLL1 KMT2A ZMYM1 TRIM29 RNF217 USP3 NOS1 ZMYM4 NR1D2 TRIM74 MPI

8.84e-0511898215GO:0046914
GeneOntologyMolecularFunctiontransforming growth factor beta binding

LTBP1 TWSG1 LTBP3

1.62e-0426823GO:0050431
GeneOntologyMolecularFunctionNAD transmembrane transporter activity

SLC25A52 SLC25A51

1.65e-045822GO:0051724
GeneOntologyMolecularFunctionscavenger receptor activity

LRP1 PRG4 EGFEM1P

1.82e-0427823GO:0005044
GeneOntologyMolecularFunctiongrowth factor binding

ERBB4 LRP2 LTBP1 TWSG1 LTBP3

4.59e-04156825GO:0019838
GeneOntologyMolecularFunctionS-adenosylmethionine-dependent methyltransferase activity

KMT2C KMT2B KMT2A SMYD5 ASH2L

7.15e-04172825GO:0008757
GeneOntologyMolecularFunctionunmethylated CpG binding

KMT2B KMT2A

7.34e-0410822GO:0045322
GeneOntologyMolecularFunctionnucleobase-containing compound transmembrane transporter activity

SLC35D3 SLC25A52 SLC25A51

1.84e-0359823GO:0015932
GeneOntologyMolecularFunctionmethyltransferase activity

KMT2C KMT2B KMT2A SMYD5 ASH2L

1.85e-03213825GO:0008168
GeneOntologyMolecularFunctiontransferase activity, transferring one-carbon groups

KMT2C KMT2B KMT2A SMYD5 ASH2L

2.30e-03224825GO:0016741
GeneOntologyBiologicalProcessresponse to growth factor

SPRY1 ERBB4 NANOGP8 TNC LRP1 LRP2 KMT2A LTBP1 TWSG1 LTBP3 NOS1 FGF18 NOTCH2 SORL1

7.90e-068838114GO:0070848
GeneOntologyBiologicalProcessmitochondrial NAD transmembrane transport

SLC25A52 SLC25A51

1.52e-052812GO:1990549
GeneOntologyBiologicalProcessnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

SPRY1 NANOGP8 LRP1 LRP2 LTBP1 TWSG1 SORL1

2.40e-05218817GO:0090101
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

SPRY1 ERBB4 NANOGP8 LRP1 LRP2 KMT2A LTBP1 TWSG1 LTBP3 NOS1 FGF18 NOTCH2 SORL1

2.53e-058508113GO:0071363
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

SPRY1 NANOGP8 LRP1 LRP2 LTBP1 TWSG1 FGF18 NOTCH2 SORL1

3.40e-05412819GO:0090287
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

SPRY1 NANOGP8 LRP1 LRP2 LTBP1 TWSG1 LTBP3 NOTCH2 SORL1

6.17e-05445819GO:0141091
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

SPRY1 NANOGP8 LRP1 LRP2 LTBP1 TWSG1 NOTCH2 SORL1

6.54e-05347818GO:0090092
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

SPRY1 NANOGP8 LRP1 LRP2 LTBP1 TWSG1 LTBP3 NOTCH2 SORL1

1.13e-04482819GO:0007178
GeneOntologyBiologicalProcessaxon guidance

LHX2 NRXN3 MATN2 LRP1 LRP2 LAMB1 NOTCH2

1.30e-04285817GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

LHX2 NRXN3 MATN2 LRP1 LRP2 LAMB1 NOTCH2

1.33e-04286817GO:0097485
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LRP1 LRP2

1.51e-045812GO:1905167
GeneOntologyBiologicalProcesschemoattraction of axon

LRP1 LRP2

1.51e-045812GO:0061642
GeneOntologyBiologicalProcessNAD transmembrane transport

SLC25A52 SLC25A51

1.51e-045812GO:0035352
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

NANOGP8 LRP2 TWSG1 NOTCH2 SORL1

1.67e-04131815GO:0030510
GeneOntologyBiologicalProcessNAD transport

SLC25A52 SLC25A51

2.26e-046812GO:0043132
GeneOntologyBiologicalProcessnegative regulation of BMP signaling pathway

NANOGP8 LRP2 TWSG1 SORL1

2.78e-0480814GO:0030514
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

SPRY1 NANOGP8 LRP2 TWSG1 SORL1

3.13e-04150815GO:0090288
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process in the vacuole

LRP1 LRP2

3.16e-047812GO:1904352
GeneOntologyCellularComponenthistone methyltransferase complex

KMT2C KMT2B KMT2A ASH2L

2.06e-0475814GO:0035097
GeneOntologyCellularComponentMLL1/2 complex

KMT2B KMT2A ASH2L

2.81e-0433813GO:0044665
GeneOntologyCellularComponentmethyltransferase complex

KMT2C KMT2B KMT2A ASH2L

8.26e-04108814GO:0034708
GeneOntologyCellularComponentMLL3/4 complex

KMT2C ASH2L

9.54e-0412812GO:0044666
GeneOntologyCellularComponentextracellular matrix

HMCN1 TNC MATN2 LAMB1 MUC5B LTBP1 LTBP3 PRG4 MUC5AC

9.74e-04656819GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

HMCN1 TNC MATN2 LAMB1 MUC5B LTBP1 LTBP3 PRG4 MUC5AC

9.95e-04658819GO:0030312
GeneOntologyCellularComponentbasement membrane

HMCN1 TNC MATN2 LAMB1

1.30e-03122814GO:0005604
DomainEGF

HYAL4 SCUBE1 NRXN3 HMCN1 SUSD1 TNC MATN2 TLL1 LRP1 LRP2 LAMB1 LTBP1 LTBP3 NOTCH2 PROS1 SORL1

3.84e-152358116SM00181
DomainEGF_2

HYAL4 SCUBE1 NRXN3 HMCN1 SUSD1 TNC MATN2 TLL1 LRP1 LRP2 LAMB1 LTBP1 LTBP3 NOTCH2 PROS1 SORL1

2.53e-142658116PS01186
DomainEGF-type_Asp/Asn_hydroxyl_site

SCUBE1 NRXN3 HMCN1 SUSD1 MATN2 TLL1 LRP1 LRP2 LTBP1 LTBP3 NOTCH2 PROS1

3.01e-141068112IPR000152
DomainEGF_CA

SCUBE1 HMCN1 SUSD1 MATN2 TLL1 LRP1 LRP2 LTBP1 LTBP3 NOTCH2 PROS1

9.51e-14868111PF07645
DomainGrowth_fac_rcpt_

ERBB4 SCUBE1 HMCN1 SUSD1 TNC MATN2 LRP1 LRP2 LAMB1 LTBP1 LTBP3 NOTCH2 PROS1

1.34e-131568113IPR009030
DomainEGF-like_dom

SCUBE1 NRXN3 HMCN1 SUSD1 TNC MATN2 TLL1 LRP1 LRP2 LAMB1 LTBP1 LTBP3 NOTCH2 PROS1 SORL1

1.82e-132498115IPR000742
DomainEGF-like_CS

SCUBE1 NRXN3 HMCN1 SUSD1 TNC MATN2 TLL1 LRP1 LRP2 LAMB1 LTBP1 LTBP3 NOTCH2 PROS1 SORL1

3.62e-132618115IPR013032
DomainASX_HYDROXYL

SCUBE1 NRXN3 HMCN1 SUSD1 MATN2 LRP1 LRP2 LTBP1 LTBP3 NOTCH2 PROS1

5.24e-131008111PS00010
DomainEGF_3

SCUBE1 NRXN3 HMCN1 SUSD1 TNC MATN2 TLL1 LRP1 LRP2 LTBP1 LTBP3 NOTCH2 PROS1 SORL1

1.46e-122358114PS50026
DomainEGF_1

HYAL4 SCUBE1 NRXN3 HMCN1 SUSD1 TNC TLL1 LRP1 LRP2 LAMB1 LTBP1 LTBP3 NOTCH2 PROS1

4.42e-122558114PS00022
DomainEGF_CA

SCUBE1 HMCN1 SUSD1 MATN2 TLL1 LRP1 LRP2 LTBP1 LTBP3 NOTCH2 PROS1

4.82e-121228111SM00179
DomainEGF-like_Ca-bd_dom

SCUBE1 HMCN1 SUSD1 MATN2 TLL1 LRP1 LRP2 LTBP1 LTBP3 NOTCH2 PROS1

5.76e-121248111IPR001881
DomainEGF_Ca-bd_CS

SCUBE1 HMCN1 SUSD1 TLL1 LRP1 LRP2 LTBP1 LTBP3 NOTCH2 PROS1

1.23e-11978110IPR018097
DomaincEGF

SCUBE1 HMCN1 MATN2 LRP1 LRP2 LTBP1 LTBP3

1.36e-1126817IPR026823
DomaincEGF

SCUBE1 HMCN1 MATN2 LRP1 LRP2 LTBP1 LTBP3

1.36e-1126817PF12662
DomainEGF_CA

SCUBE1 HMCN1 SUSD1 TLL1 LRP1 LRP2 LTBP1 LTBP3 NOTCH2 PROS1

1.51e-11998110PS01187
DomainEGF

NRXN3 HMCN1 TNC MATN2 TLL1 LRP1 LRP2 LTBP1 NOTCH2 PROS1

1.70e-101268110PF00008
DomainFYrich_C

KMT2C KMT2B KMT2A

7.81e-075813IPR003889
DomainFYrich_N

KMT2C KMT2B KMT2A

7.81e-075813IPR003888
DomainFYRC

KMT2C KMT2B KMT2A

7.81e-075813SM00542
DomainFYRN

KMT2C KMT2B KMT2A

7.81e-075813SM00541
DomainFYRN

KMT2C KMT2B KMT2A

7.81e-075813PF05964
DomainFYRC

KMT2C KMT2B KMT2A

7.81e-075813PF05965
DomainFYRC

KMT2C KMT2B KMT2A

7.81e-075813PS51543
DomainFYRN

KMT2C KMT2B KMT2A

7.81e-075813PS51542
DomainEPHD

KMT2C KMT2B BRPF1 KMT2A

2.26e-0622814PS51805
DomainMeTrfase_trithorax

KMT2B KMT2A

1.86e-052812IPR016569
DomainPMG

KRTAP13-3 KRTAP23-1 KRTAP15-1

2.18e-0513813PF05287
DomainKRTAP_PMG

KRTAP13-3 KRTAP23-1 KRTAP15-1

2.18e-0513813IPR007951
DomainLDLR_class-A_CS

NETO1 LRP1 LRP2 SORL1

2.66e-0540814IPR023415
DomainTIL_dom

LRP2 MUC5B MUC5AC

2.76e-0514813IPR002919
DomainLdl_recept_b

LRP1 LRP2 SORL1

2.76e-0514813PF00058
DomainLDLRB

LRP1 LRP2 SORL1

2.76e-0514813PS51120
DomainSET

KMT2C KMT2B KMT2A SMYD5

2.94e-0541814PF00856
DomainLY

LRP1 LRP2 SORL1

3.44e-0515813SM00135
DomainLDLR_classB_rpt

LRP1 LRP2 SORL1

3.44e-0515813IPR000033
DomainPost-SET_dom

KMT2C KMT2B KMT2A

4.23e-0516813IPR003616
DomainPostSET

KMT2C KMT2B KMT2A

4.23e-0516813SM00508
DomainPOST_SET

KMT2C KMT2B KMT2A

4.23e-0516813PS50868
DomainLdl_recept_a

NETO1 LRP1 LRP2 SORL1

4.27e-0545814PF00057
DomainSET

KMT2C KMT2B KMT2A SMYD5

4.66e-0546814SM00317
Domain-

NETO1 LRP1 LRP2 SORL1

4.66e-05468144.10.400.10
DomainLDLRA_1

NETO1 LRP1 LRP2 SORL1

5.52e-0548814PS01209
DomainLDLRA_2

NETO1 LRP1 LRP2 SORL1

6.00e-0549814PS50068
DomainLDrepeatLR_classA_rpt

NETO1 LRP1 LRP2 SORL1

6.00e-0549814IPR002172
DomainLDLa

NETO1 LRP1 LRP2 SORL1

6.00e-0549814SM00192
DomainSET_dom

KMT2C KMT2B KMT2A SMYD5

6.50e-0550814IPR001214
DomainSET

KMT2C KMT2B KMT2A SMYD5

6.50e-0550814PS50280
Domain-

KMT2C KMT2B TRIM73 BRPF1 MKRN1 CHFR KMT2A USP3 TRIM74

1.40e-044498193.30.40.10
DomainZnf_RING/FYVE/PHD

KMT2C KMT2B TRIM73 BRPF1 MKRN1 CHFR KMT2A USP3 TRIM74

1.65e-04459819IPR013083
DomainAT_hook

KMT2C KMT2B KMT2A

2.13e-0427813SM00384
DomainAT_hook_DNA-bd_motif

KMT2C KMT2B KMT2A

2.13e-0427813IPR017956
DomainWxxW_domain

MUC5B MUC5AC

2.76e-046812IPR025155
DomainMucin2_WxxW

MUC5B MUC5AC

2.76e-046812PF13330
DomainHaem_d1

STXBP5L KMT2A

2.76e-046812IPR011048
DomainTB

LTBP1 LTBP3

3.85e-047812PF00683
DomainZnf_MYM

ZMYM1 ZMYM4

3.85e-047812IPR010507
Domainzf-FCS

ZMYM1 ZMYM4

3.85e-047812PF06467
DomainZnf_PHD-finger

KMT2C KMT2B BRPF1 KMT2A

3.85e-0479814IPR019787
DomainTRASH_dom

ZMYM1 ZMYM4

5.11e-048812IPR011017
DomainTRASH

ZMYM1 ZMYM4

5.11e-048812SM00746
Domain-

LTBP1 LTBP3

5.11e-0488123.90.290.10
DomainPHD

KMT2C KMT2B BRPF1 KMT2A

6.06e-0489814SM00249
Domain-

LRP1 LRP2 SORL1

6.42e-04398132.120.10.30
DomainTB

LTBP1 LTBP3

6.56e-049812PS51364
DomainTB_dom

LTBP1 LTBP3

6.56e-049812IPR017878
DomainZnf_PHD

KMT2C KMT2B BRPF1 KMT2A

6.59e-0491814IPR001965
DomainZF_PHD_2

KMT2C KMT2B BRPF1 KMT2A

7.75e-0495814PS50016
DomainZF_PHD_1

KMT2C KMT2B BRPF1 KMT2A

8.06e-0496814PS01359
Domain-

HMCN1 SUSD1

9.96e-04118122.40.155.10
DomainGFP-like

HMCN1 SUSD1

9.96e-0411812IPR023413
DomainZnf_CXXC

KMT2B KMT2A

9.96e-0411812IPR002857
DomainZF_CXXC

KMT2B KMT2A

9.96e-0411812PS51058
Domainzf-CXXC

KMT2B KMT2A

9.96e-0411812PF02008
Domain6-blade_b-propeller_TolB-like

LRP1 LRP2 SORL1

1.04e-0346813IPR011042
DomainTIL

MUC5B MUC5AC

1.19e-0312812PF01826
DomainC8

MUC5B MUC5AC

1.19e-0312812PF08742
DomainCUB

SCUBE1 NETO1 TLL1

1.25e-0349813PF00431
DomainCUB

SCUBE1 NETO1 TLL1

1.33e-0350813SM00042
DomainUnchr_dom_Cys-rich

MUC5B MUC5AC

1.40e-0313812IPR014853
DomainC8

MUC5B MUC5AC

1.40e-0313812SM00832
Domain-

SCUBE1 NETO1 TLL1

1.49e-03528132.60.120.290
DomainCUB

SCUBE1 NETO1 TLL1

1.57e-0353813PS01180
DomainZF_RING_2

KMT2C TRIM73 MKRN1 CHFR RNF217 TRIM74

1.87e-03298816PS50089
DomainGlyco_hormone_CN

MUC5B MUC5AC

1.88e-0315812IPR006208
DomainCys_knot

MUC5B MUC5AC

1.88e-0315812PF00007
DomainCUB_dom

SCUBE1 NETO1 TLL1

1.94e-0357813IPR000859
DomainVWD

MUC5B MUC5AC

2.14e-0316812SM00216
DomainVWF_type-D

MUC5B MUC5AC

2.14e-0316812IPR001846
DomainVWFD

MUC5B MUC5AC

2.14e-0316812PS51233
DomainAT_hook

KMT2C KMT2A

2.14e-0316812PF02178
DomainVWD

MUC5B MUC5AC

2.14e-0316812PF00094
DomainCTCK_1

MUC5B MUC5AC

2.72e-0318812PS01185
DomainVWC_out

MUC5B MUC5AC

3.03e-0319812SM00215
DomainBBOX

TRIM73 TRIM29 TRIM74

3.35e-0369813SM00336
DomainLIM

LHX2 LIMD1 WTIP

3.35e-0369813PF00412
Domain-

LHX2 LIMD1 WTIP

3.49e-03708132.10.110.10
DomainZnf_LIM

LHX2 LIMD1 WTIP

3.63e-0371813IPR001781
DomainLIM_DOMAIN_1

LHX2 LIMD1 WTIP

3.63e-0371813PS00478
DomainLIM_DOMAIN_2

LHX2 LIMD1 WTIP

3.63e-0371813PS50023
PathwayREACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES

KMT2C KMT2B KMT2A ASH2L

2.94e-0542604M48018
Pubmed

Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.

KMT2C KMT2B ZC3H4 KMT2A POGZ ARHGEF17 ASH2L ZNF639

4.27e-1011982823508102
Pubmed

Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.

KMT2C KMT2B KMT2A ASH2L

3.58e-09982422665483
Pubmed

Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.

KMT2C KMT2B KMT2A ASH2L

1.40e-081282427563068
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

STXBP5L LRP1 LRP2 LTBP3 MUC5AC SPINK5

1.81e-087182633541421
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

KMT2C KMT2B KMT2A ASH2L

2.02e-081382424619213
Pubmed

A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.

KMT2C KMT2B KMT2A

5.04e-08482323129768
Pubmed

SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.

KMT2C KMT2B KMT2A ASH2L

5.11e-081682423870121
Pubmed

Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.

MSRB2 KMT2C KMT2B KMT2A ASH2L

1.26e-075082537974198
Pubmed

Evolving Catalytic Properties of the MLL Family SET Domain.

KMT2B KMT2A ASH2L

1.26e-07582326320581
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP1 LRP2 SORL1

1.26e-07582319047013
Pubmed

Structural basis for activity regulation of MLL family methyltransferases.

KMT2C KMT2B KMT2A ASH2L

2.03e-072282426886794
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

SPRY1 MATN2 LRP1 LAMB1 LTBP1 LTBP3

3.81e-0711882621078624
Pubmed

Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4.

KMT2C KMT2B ASH2L

4.39e-07782330604749
Pubmed

A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4.

KMT2C KMT2B ASH2L

4.39e-07782319433796
Pubmed

Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex.

KMT2C KMT2A ASH2L

4.39e-07782326324722
Pubmed

Rebalancing gene haploinsufficiency in vivo by targeting chromatin.

KMT2C NANOGP8 KMT2B KMT2A

5.63e-072882427256596
Pubmed

Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.

KMT2C KMT2B KMT2A

7.01e-07882323130995
Pubmed

The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.

KMT2C KMT2B KMT2A

7.01e-07882322266653
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

LHX2 KMT2C DEAF1 LIMD1 BRPF1 MKRN1 KMT2A POGZ ASH2L NR1D2 ZNF639

8.81e-07709821122988430
Pubmed

Impact of WIN site inhibitor on the WDR5 interactome.

KMT2C KMT2B KMT2A ASH2L

3.30e-064382433472061
Pubmed

Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis.

KMT2C KMT2B ASH2L

3.55e-061382321502505
Pubmed

Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.

KMT2C NANOGP8 KMT2B KMT2A

3.63e-064482424183668
Pubmed

Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.

LRP1 LRP2 MUC5B MUC5AC

4.74e-064782411208732
Pubmed

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

MUC5B MUC5AC

5.49e-0628227513696
Pubmed

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

MUC5B MUC5AC

5.49e-06282234058148
Pubmed

The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

MUC5B MUC5AC

5.49e-06282237146737
Pubmed

KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.

KMT2B KMT2A

5.49e-06282228723559
Pubmed

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

MUC5B MUC5AC

5.49e-06282214988081
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

5.49e-06282234445520
Pubmed

Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.

MUC5B MUC5AC

5.49e-06282215563276
Pubmed

The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.

MUC5B MUC5AC

5.49e-06282217621824
Pubmed

Muc5b is required for airway defence.

MUC5B MUC5AC

5.49e-06282224317696
Pubmed

Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.

MUC5B MUC5AC

5.49e-06282222391959
Pubmed

C-Mannosylation of MUC5AC and MUC5B Cys subdomains.

MUC5B MUC5AC

5.49e-06282214718370
Pubmed

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

MUC5B MUC5AC

5.49e-06282235776514
Pubmed

The ocular surface phenotype of Muc5ac and Muc5b null mice.

MUC5B MUC5AC

5.49e-06282224327612
Pubmed

Mucin production during prenatal and postnatal murine lung development.

MUC5B MUC5AC

5.49e-06282221653907
Pubmed

MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.

MUC5B MUC5AC

5.49e-06282236427316
Pubmed

Bruton's Tyrosine Kinase Synergizes with Notch2 To Govern Marginal Zone B Cells in Nonobese Diabetic Mice.

BTK NOTCH2

5.49e-06282226034172
Pubmed

Gel-forming mucins form distinct morphologic structures in airways.

MUC5B MUC5AC

5.49e-06282228607090
Pubmed

nNOS in Erbb4-positive neurons regulates GABAergic transmission in mouse hippocampus.

ERBB4 NOS1

5.49e-06282238396027
Pubmed

Mucin deficiency causes functional and structural changes of the ocular surface.

MUC5B MUC5AC

5.49e-06282223272068
Pubmed

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.

MUC5B MUC5AC

5.49e-06282231030254
Pubmed

Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.

MUC5B MUC5AC

5.49e-06282227729120
Pubmed

Extracellular matrix changes in corneal opacification vary depending on etiology.

TNC MATN2

5.49e-06282233633437
Pubmed

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.

MUC5B MUC5AC

5.49e-06282223527003
Pubmed

Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.

MUC5B MUC5AC

5.49e-06282216540890
Pubmed

De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.

MUC5B MUC5AC

5.49e-06282236111525
Pubmed

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

MUC5B MUC5AC

5.49e-06282227845589
Pubmed

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

MUC5B MUC5AC

5.49e-06282227435107
Pubmed

Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.

MUC5B MUC5AC

5.49e-06282226871672
Pubmed

Aggregated low-density lipoprotein induces LRP1 stabilization through E3 ubiquitin ligase CHFR downregulation in human vascular smooth muscle cells.

CHFR LRP1

5.49e-06282223241409
Pubmed

SLC25A51 is a mammalian mitochondrial NAD+ transporter.

SLC25A52 SLC25A51

5.49e-06282232906142
Pubmed

ASH2L regulates ubiquitylation signaling to MLL: trans-regulation of H3 K4 methylation in higher eukaryotes.

KMT2A ASH2L

5.49e-06282223453805
Pubmed

Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.

MUC5B MUC5AC

5.49e-06282232348677
Pubmed

In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.

MUC5B MUC5AC

5.49e-06282211587997
Pubmed

Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.

MUC5B MUC5AC

5.49e-06282224332705
Pubmed

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

MUC5B MUC5AC

5.49e-06282234656442
Pubmed

Human transcription factor protein interaction networks.

ASNSD1 LHX2 KMT2C DEAF1 KMT2B LIMD1 LRP2 KMT2A POGZ ZMYM1 ASH2L DCAF5 ZMYM4 SORL1

5.89e-061429821435140242
Pubmed

Cyclin B1/Cdk1 binds and phosphorylates Filamin A and regulates its ability to cross-link actin.

SCUBE1 SLC25A52 SLC25A51

6.92e-061682317408621
Pubmed

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.

KMT2C KMT2B ASH2L

6.92e-061682324368734
Pubmed

MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.

KMT2C KMT2B ASH2L

8.39e-061782326180087
Pubmed

Architectural niche organization by LHX2 is linked to hair follicle stem cell function.

LHX2 TNC FGF18

1.00e-051882324012369
Pubmed

PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.

KMT2C KMT2B ASH2L

1.00e-051882317500065
Pubmed

A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.

KMT2C KMT2B KMT2A ASH2L

1.35e-056182420305087
Pubmed

Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.

KMT2C KMT2B ASH2L

1.40e-052082319047629
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

NANOGP8 LRP1 LRP2

1.63e-052182321337463
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KMT2C KMT2B KMT2A

1.63e-052182327626377
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

HMCN1 TNC MATN2 LAMB1

1.64e-056482422261194
Pubmed

Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.

MUC5B MUC5AC

1.64e-05382227776277
Pubmed

Tenascin-C is a novel RBPJkappa-induced target gene for Notch signaling in gliomas.

TNC NOTCH2

1.64e-05382219147558
Pubmed

High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.

MUC5B MUC5AC

1.64e-05382229286856
Pubmed

Tension-dependent regulation of mammalian Hippo signaling through LIMD1.

LIMD1 WTIP

1.64e-05382229440237
Pubmed

Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.

MUC5B MUC5AC

1.64e-05382236675209
Pubmed

The mitochondrial NAD+ transporter SLC25A51 is a fasting-induced gene affecting SIRT3 functions.

SLC25A52 SLC25A51

1.64e-05382235932995
Pubmed

Structural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marks.

KMT2A ASH2L

1.64e-05382219187761
Pubmed

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.

MUC5B MUC5AC

1.64e-05382229802623
Pubmed

Isolation of a novel latent transforming growth factor-beta binding protein gene (LTBP-3).

LTBP1 LTBP3

1.64e-0538227730318
Pubmed

Gene structure variation in segmental duplication block C of human chromosome 7q 11.23 during primate evolution.

TRIM73 TRIM74

1.64e-05382226196062
Pubmed

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

KMT2C KMT2A

1.64e-05382223932714
Pubmed

MUC5B mucin production is upregulated by fibronectin and laminin in human lung epithelial cells via the integrin and ERK dependent pathway.

LAMB1 MUC5B

1.64e-05382226057585
Pubmed

Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.

MUC5B MUC5AC

1.64e-05382234158522
Pubmed

Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.

MUC5B MUC5AC

1.64e-05382229604272
Pubmed

IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.

MUC5B MUC5AC

1.64e-05382219596978
Pubmed

Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA.

LRP1 SORL1

1.64e-05382228799085
Pubmed

Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.

MUC5B MUC5AC

1.64e-05382219556605
Pubmed

Aquaporin 5 expression increases mucin production in lung adenocarcinoma.

MUC5B MUC5AC

1.64e-05382221455588
Pubmed

Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.

MUC5B MUC5AC

1.64e-05382220422702
Pubmed

TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells.

TRIM73 TRIM74

1.64e-05382222872646
Pubmed

Latent TGF-beta binding proteins (LTBPs)-1 and -3 coordinate proliferation and osteogenic differentiation of human mesenchymal stem cells.

LTBP1 LTBP3

1.64e-05382218672106
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC5B MUC5AC

1.64e-05382219718741
Pubmed

Latent transforming growth factor-beta binding proteins (LTBPs)--structural extracellular matrix proteins for targeting TGF-beta action.

LTBP1 LTBP3

1.64e-05382210743502
Pubmed

USP16-mediated histone H2A lysine-119 deubiquitination during oocyte maturation is a prerequisite for zygotic genome activation.

NANOGP8 ANKRD22 USP3

1.88e-052282335640597
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

TNC MATN2 LAMB1 LTBP1 LTBP3

2.56e-0514682527068509
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

KMT2C NANOGP8 KMT2B POGZ ASH2L

2.56e-0514682523892456
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

TNC MATN2 LAMB1 LTBP1 PRG4 PROS1

2.75e-0524882624006456
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

KMT2C KMT2B ZC3H4 KMT2A POGZ ASH2L

2.95e-0525182631076518
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

TNC MATN2 LAMB1 LTBP1 PRG4

3.20e-0515382525037231
Pubmed

Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.

KMT2C KMT2B

3.28e-05482219221051
Pubmed

A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit.

KMT2A ASH2L

3.28e-05482220064463
InteractionZFP41 interactions

ZC3H4 LRP1 LRP2 LTBP1 NOTCH2 SORL1

8.57e-0857786int:ZFP41
InteractionNTN5 interactions

LRP2 LTBP1 NOTCH2 SORL1

2.08e-0624784int:NTN5
InteractionCACNA1A interactions

SPRY1 MATN2 LRP1 LAMB1 LTBP1 LTBP3

8.20e-06123786int:CACNA1A
InteractionZDHHC15 interactions

STXBP5L LRP1 LRP2 LTBP3 MUC5AC SPINK5

9.00e-06125786int:ZDHHC15
InteractionKRTAP3-2 interactions

SPRY1 KRTAP13-3 POGZ KRTAP15-1 NR1D2

1.37e-0579785int:KRTAP3-2
InteractionHCFC2 interactions

KMT2C POLR3K KMT2B KMT2A ASH2L

2.88e-0592785int:HCFC2
InteractionZNF816 interactions

DCAF1 DCAF5 SORL1

3.01e-0516783int:ZNF816
InteractionPHF20 interactions

KMT2C KMT2B KMT2A ASH2L

5.26e-0553784int:PHF20
InteractionASH2L interactions

MSRB2 LHX2 KMT2C KMT2B MKRN1 KMT2A ASH2L

7.49e-05265787int:ASH2L
InteractionANKRD36B interactions

LRP1 LRP2 POGZ SORL1

8.59e-0560784int:ANKRD36B
InteractionATN1 interactions

KMT2C KMT2B LRP2 KMT2A LTBP1 KRTAP15-1

8.69e-05187786int:ATN1
InteractionELF1 interactions

KMT2B KMT2A POGZ ASH2L ZMYM4

1.29e-04126785int:ELF1
InteractionMYB interactions

KMT2B KMT2A POGZ ASH2L ZMYM4

1.67e-04133785int:MYB
InteractionH3C1 interactions

DCAF1 KMT2C KMT2B ZC3H4 BRPF1 KMT2A SMYD5 POGZ TRIM29 USP3 ASH2L ZMYM4

1.69e-049017812int:H3C1
InteractionKMT2C interactions

LHX2 KMT2C KMT2B KMT2A ASH2L

1.73e-04134785int:KMT2C
InteractionIGFL3 interactions

LRP2 LAMB1 NOTCH2 SORL1

2.05e-0475784int:IGFL3
InteractionSETD1B interactions

KMT2C KMT2B KMT2A ASH2L

2.05e-0475784int:SETD1B
Cytoband21q22.1

KRTAP13-3 KRTAP23-1 KRTAP15-1

4.79e-053982321q22.1
Cytoband11p15.5

DEAF1 MUC5B MUC5AC

1.26e-0311882311p15.5
CytobandEnsembl 112 genes in cytogenetic band chr9p13

FRMPD1 ALDH1B1 SLC25A51

3.81e-03174823chr9p13
GeneFamilyPHD finger proteins

KMT2C KMT2B BRPF1 KMT2A ASH2L

2.07e-059067588
GeneFamilyLatent transforming growth factor beta binding proteins

LTBP1 LTBP3

8.08e-054672628
GeneFamilyZinc fingers MYM-type

ZMYM1 ZMYM4

2.01e-04667286
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2C KMT2B KMT2A

2.68e-0434673487
GeneFamilyKeratin associated proteins

KRTAP13-3 KRTAP23-1 KRTAP29-1 KRTAP15-1

7.15e-04109674619
GeneFamilyZinc fingers CXXC-type

KMT2B KMT2A

8.72e-0412672136
GeneFamilyLow density lipoprotein receptors

LRP1 LRP2

1.03e-0313672634
GeneFamilyWD repeat domain containing|DDB1 and CUL4 associated factors

DCAF1 DCAF5

1.99e-0318672498
GeneFamilyZinc fingers MYND-type

DEAF1 SMYD5

2.71e-032167287
GeneFamilyCD molecules|Mucins

MUC5B MUC5AC

2.71e-0321672648
GeneFamilyRing finger proteins

TRIM73 MKRN1 CHFR RNF217 TRIM74

3.52e-0327567558
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM73 TRIM29 TRIM74

5.28e-039567359
CoexpressionNABA_CORE_MATRISOME

HMCN1 TNC MATN2 LAMB1 LTBP1 LTBP3 PRG4 EGFEM1P

1.92e-06270818MM17057
CoexpressionNABA_ECM_GLYCOPROTEINS

HMCN1 TNC MATN2 LAMB1 LTBP1 LTBP3 EGFEM1P

2.16e-06191817MM17059
CoexpressionNABA_MATRISOME

HYAL4 SCUBE1 HMCN1 TNC MATN2 TLL1 LAMB1 MUC5B LTBP1 LTBP3 PRG4 MUC5AC FGF18 EGFEM1P

2.34e-0610088114MM17056
CoexpressionNABA_MATRISOME

HYAL4 SCUBE1 HMCN1 TNC MATN2 TLL1 LAMB1 MUC5B LTBP1 LTBP3 PRG4 MUC5AC FGF18

1.49e-0510268113M5889
CoexpressionNABA_CORE_MATRISOME

HMCN1 TNC MATN2 LAMB1 LTBP1 LTBP3 PRG4

2.32e-05275817M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

HMCN1 TNC MATN2 LAMB1 LTBP1 LTBP3

3.30e-05196816M3008
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000

ANKRD22 ZNF560 HMCN1 ZC3H4 TNC TLL1 SLC35D3 FRMPD1 LAMB1 PXYLP1 LTBP1 TRIM29 SORL1

7.86e-068507513gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000
CoexpressionAtlasStromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5

HMCN1 TNC MATN2 LRP1 LAMB1 DAPK1 LTBP1 LTBP3 PROS1

3.81e-05466759GSM777050_500
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LAMB1 LTBP1 TWSG1 LTBP3 NR1D2 PROS1

3.04e-09196828b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LAMB1 LTBP1 TWSG1 LTBP3 NR1D2 PROS1

3.04e-09196828787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellfacs-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LAMB1 LTBP1 TWSG1 LTBP3 PROS1

8.27e-081988270dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCUBE1 MATN2 LRP1 LTBP1 LTBP3 ARHGEF17 NOS1

8.56e-08199827fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

SPRY1 TNC MATN2 LRP1 LAMB1 LTBP1 LTBP3

8.85e-08200827a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SPRY1 TNC MATN2 LRP1 LAMB1 LTBP1 LTBP3

8.85e-0820082709537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMCN1 LIMD1 KMT2A LTBP1 ZMYM1 NOTCH2

1.32e-061888266468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMCN1 LIMD1 KMT2A LTBP1 ZMYM1 NOTCH2

1.32e-061888267a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMCN1 LIMD1 KMT2A LTBP1 ZMYM1 NOTCH2

1.32e-061888269cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SPRY1 HMCN1 TNC TWSG1 LTBP3 FGF18

1.45e-061918269bbafdf316c1fa3a9f1ee30d41dd7158b5c97279
ToppCellfacs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHX2 HMCN1 MATN2 LTBP3 TRIM29 FGF18

1.54e-06193826eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LAMB1 LTBP1 TWSG1 LTBP3

1.54e-06193826d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCellPND01-03-samps-Mesenchymal|PND01-03-samps / Age Group, Lineage, Cell class and subclass

LIMD1 TNC LRP1 LAMB1 TWSG1 NOTCH2

1.59e-061948264f9bd0ded0dde1df885850714f29e73e992539a5
ToppCellfacs-Skin-Anagen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHX2 HMCN1 MATN2 LTBP3 TRIM29 FGF18

1.59e-061948265d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCellfacs-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMB1 TWSG1 LTBP3 NOTCH2 NR1D2 PROS1

1.63e-06195826c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCellBronchial_Brush-Epithelial-Basal_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

SPRY1 HMCN1 TNC LAMB1 FGF18 SPINK5

1.73e-06197826f5d87824c0020c95d89e069fd9f70b49e5d5fcea
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HMCN1 MATN2 TWSG1 LTBP3 PRG4 FGF18

1.73e-061978263fe665c0277d091290b63f0dd24c0c6536a45309
ToppCellP07-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPRY1 NRXN3 HMCN1 TNC FGF18 PROS1

1.73e-06197826b1135378d768fbbe62a75747d1e8653d35252187
ToppCellfacs-Heart-LA-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LAMB1 LTBP1 TWSG1 NOTCH2

1.73e-061978262a91738cb6d7588869dd00deeea0cbbc2d6aa34d
ToppCellBronchial_Brush-Epithelial-Basal_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SPRY1 HMCN1 TNC LAMB1 FGF18 SPINK5

1.79e-0619882610a17d7c116dcd6cf847fe6f5d7196d887cad1f9
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TNC LRP1 LTBP1 LTBP3 ARHGEF17 PROS1

1.79e-06198826399760b6b6fef8639ded53b14f251b9fce600e81
ToppCell(5)_Fibroblast-G|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SPRY1 HMCN1 TNC LRP1 LAMB1 PRG4

1.84e-06199826b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SPRY1 TNC MATN2 LRP1 LAMB1 LTBP3

1.84e-0619982638cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell343B-Fibroblasts-Fibroblast-G|343B / Donor, Lineage, Cell class and subclass (all cells)

SPRY1 HMCN1 TNC LRP1 LAMB1 PRG4

1.84e-06199826f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell343B-Fibroblasts-Fibroblast-G-|343B / Donor, Lineage, Cell class and subclass (all cells)

SPRY1 HMCN1 TNC LRP1 LAMB1 PRG4

1.84e-061998269c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCellControl_saline-Mesenchymal_myocytic|Control_saline / Treatment groups by lineage, cell group, cell type

SPRY1 TNC LRP1 LAMB1 LTBP1 ARHGEF17

1.89e-062008265ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SPRY1 TNC MATN2 LAMB1 LTBP3 ARHGEF17

1.89e-0620082667dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SPRY1 HMCN1 TNC LRP1 LAMB1 LTBP1

1.89e-06200826251fd2923f108cd2086961d897244b392c32ad54
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SPRY1 MATN2 LRP1 LAMB1 LTBP1 TWSG1

1.89e-06200826efdf7066b7dd43e35dbc0d2719b75f250cf54af2
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

SPRY1 MATN2 LRP1 LAMB1 ARHGEF17 NOTCH2

1.89e-06200826bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellfacs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHX2 HMCN1 TNC MATN2 LTBP3

1.44e-0516782578909f685ccd1321064eb0887caf9263e0e54879
ToppCelldroplet-Heart-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 LRP1 DAPK1 TWSG1 NOTCH2

1.52e-051698252e5bb6437bc9c614e337c5ffb6f6457cd9fc7f4c
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCUBE1 HMCN1 TNC LAMB1 LTBP1

2.12e-05181825b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

HMCN1 NETO1 LAMB1 LTBP1 PRG4

2.12e-05181825bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMCN1 TNC MATN2 LRP1 LAMB1

2.17e-051828253dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 TRIM29 PRG4 MUC5AC FGF18

2.23e-051838259d5a363fbe6f0a1668c9d584df65ee1c283349c7
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP2 TRIM29 PRG4 MUC5AC FGF18

2.23e-05183825c5caac6ed6c8d67f5c336281d9fd903976509445
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 LTBP1 NOS1 EGFEM1P NOTCH2

2.29e-05184825e2de27cee3ea80f9b7a9a7884ceceeaa67b3214a
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHX2 SCUBE1 TNC LAMB1 ARHGEF17

2.35e-05185825f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SPRY1 NRXN3 HMCN1 TNC FGF18

2.35e-05185825427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHX2 SCUBE1 TNC LAMB1 ARHGEF17

2.35e-0518582540e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHX2 SCUBE1 TNC LAMB1 ARHGEF17

2.35e-051858255f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 FRMPD1 LTBP1 NOS1 EGFEM1P

2.54e-051888258268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 LTBP1 NOS1 EGFEM1P NOTCH2

2.54e-051888254544552ebd67e9eb3e40d8511bb2b03a6e1178f8
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 MATN2 LTBP1 NOS1 EGFEM1P

2.54e-051888253139540a656c0436b2123ea50741ff8d00112165
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERBB4 NRXN3 TLL1 LRP2 SORL1

2.60e-051898257659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHX2 HMCN1 TNC MATN2 LTBP3

2.60e-05189825d00410010283dc6191ce9857d6c7952678fed588
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 MATN2 LTBP1 NOS1 EGFEM1P

2.67e-051908252f54da2bee411f8868348a4c37034184b8f58a89
ToppCellfacs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNC TWSG1 LTBP3 FGF18 NR1D2

2.67e-05190825c7bd087f36321cec61b98657433b4d19d135791f
ToppCellfacs-Lung-nan-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNC TWSG1 LTBP3 FGF18 NR1D2

2.67e-05190825834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP1 TWSG1 LTBP3 ZMYM4

2.74e-051918259214655dca96d766737c9f30b624d7fe7050342e
ToppCelldroplet-Heart-HEART-1m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 HMCN1 FRMPD1 PAQR3 NR1D2

2.74e-051918254bfdf44d4402a42530d30c89d94946acdda4321b
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MATN2 LRP1 LAMB1 LTBP1 LTBP3

2.81e-0519282532acd89617934016cd135d2cc797e8e79ae1b37f
ToppCelldroplet-Fat-Mat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LAMB1 DAPK1 LTBP3

2.88e-05193825ebd090d7801480b3cee45caac3d30cc991836769
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LAMB1 DAPK1 LTBP3

2.88e-0519382522c58032e58730715224d7934968ce92d150b0e8
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LTBP1 LTBP3 PRG4

2.88e-051938250a665531d581d4e3941e29d3f95569da8f166447
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NETO1 TNC MATN2 LRP1 LTBP1

2.88e-05193825dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LTBP1 LTBP3 PRG4

2.88e-0519382524ce1f37cca655415410d2403a52d1ebb3332280
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LAMB1 DAPK1 LTBP3

2.88e-05193825573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NETO1 TNC MATN2 LRP1 LTBP1

2.88e-05193825e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPRY1 TNC MATN2 LRP1 LAMB1

2.95e-05194825e2db75f4de114631b8bda4e188f84446545538b7
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHX2 SPRY1 NRXN3 LAMB1 ARHGEF17

2.95e-05194825415801a3dfacf05f2b603fb424df3d045190a812
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LTBP1 LTBP3 PRG4

2.95e-051948252d0cff9dc538a14518741e2a96d9d78442c81a72
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHX2 SPRY1 NRXN3 LAMB1 ARHGEF17

2.95e-05194825256cb33ec90328f2704921fb0fe0fd9812e138b0
ToppCellfacs-Heart-RA-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LTBP3 FGF18 NOTCH2

2.95e-05194825bc945450b350f597c3ff910d3a14a533d90086a8
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERBB4 NRXN3 TLL1 LRP2 SORL1

2.95e-05194825f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHX2 SPRY1 NRXN3 LAMB1 ARHGEF17

2.95e-051948257942bc83c1bdca687795b91aa232824d603f9b09
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LAMB1 LTBP1 TWSG1 LTBP3

3.02e-0519582569a29d03e664b72f32d41876510c62345c3aed31
ToppCellfacs-Heart-LA-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LTBP1 TWSG1 NOTCH2

3.02e-0519582579a6e8e6de040ff07539e8901fc407363a50e355
ToppCellfacs-GAT-Fat-3m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LAMB1 LTBP1 TWSG1 LTBP3

3.02e-051958251cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCellFibroblast-B_(Myofibroblast)|World / shred on cell class and cell subclass (v4)

NRXN3 HMCN1 TNC FGF18 PROS1

3.02e-05195825a8d6416518f226e1ec2d6bdc9d4b90cef5cb1365
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LAMB1 LTBP1 TWSG1 LTBP3

3.02e-051958259cef6f18664518060af7c192310dddce6d70345a
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 LRP1 LRP2 LAMB1 LTBP1

3.10e-051968256bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMCN1 LRP1 LRP2 LAMB1 LTBP1

3.10e-05196825c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NRXN3 TNC LTBP3 FGF18 PROS1

3.10e-051968259d7b631f24a19a7dc7a28f28525d4019fc8fcf8a
ToppCellfacs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LTBP1 TWSG1 NOTCH2

3.10e-05196825ad1838dabd043cb140260843e3527d8c7d58850e
ToppCellMatrixFB-Fibroblast-B_(Myofibroblast)|MatrixFB / shred on cell class and cell subclass (v4)

SPRY1 NRXN3 HMCN1 TNC FGF18

3.10e-0519682538ea0eaf42f95c321ca23570d0d7752980cf00f8
ToppCellfacs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 LRP1 LTBP1 TWSG1 NOTCH2

3.10e-05196825cbc15c0769016fe9972445169029bd8d14a7e6ef
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NRXN3 TNC LTBP3 FGF18 PROS1

3.18e-051978257d97c2d51a543c02d679e9257b22d0581e73a11d
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LHX2 TNC LRP1 LAMB1 LTBP1

3.18e-05197825fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCUBE1 MATN2 LRP1 LAMB1 LTBP1

3.18e-051978252cb1f557ce1400398975de94638126b4522567f3
ToppCellAT2_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

NRXN3 TNC LRP2 MUC5B SPINK5

3.18e-05197825fd7bdfa6bf5966ebc11fdd13915769429540ddbf
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN1 TNC LAMB1 FGF18 PROS1

3.18e-0519782526475b9e4d6bfc0ae818dea13d139888ed7e92f1
ToppCellP03-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NRXN3 HMCN1 TNC FGF18 PROS1

3.18e-051978252cec938caf6ffd031cea37277071487e59b2c71c
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NRXN3 TNC LTBP3 FGF18 PROS1

3.18e-05197825671d6b5effbac2dd71d18f48d23c523738db1828
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NRXN3 HMCN1 TNC FGF18 PROS1

3.18e-051978259d7a1c7dc70ba5e35645f19f9e056e4fa2494aa0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NETO1 TNC MATN2 LRP1 LTBP1

3.18e-051978254cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NRXN3 HMCN1 TNC FGF18 PROS1

3.18e-05197825090a251194da3e2806989d9a522588f83f52da7f
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NRXN3 HMCN1 TNC FGF18 PROS1

3.18e-0519782543b5f8e917506c1717f9311584901b506ffd2c79
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN1 TNC LAMB1 FGF18 PROS1

3.18e-05197825155e63b33302a87393ace699b2f6d73abe9c5763
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPRY1 TNC LAMB1 FGF18 PROS1

3.25e-05198825b2d295e330772bd8e24da356c75564b4297ea9c5
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPRY1 TNC LAMB1 FGF18 PROS1

3.25e-05198825ce59ee3d970397eb62d6387699c6c6cd65457898
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN1 TNC LAMB1 FGF18 PROS1

3.25e-05198825a4005a49cf6709b543994ceb51ecd5dc46197fa9
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SPRY1 SCUBE1 LTBP1 ARHGEF17 FGF18

3.25e-05198825c9c96066c7fa897b583657f0b77ea093920ae9ba
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNC MATN2 LRP1 LTBP3 NR1D2

3.25e-05198825524305c5d7b1d53e86ec0af775efefa3e0955e47
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPRY1 TNC LAMB1 FGF18 PROS1

3.25e-051988253ffaea4b44067d69f954b2bd3119c88a55ab232a
ToppCellFibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

TNC LRP1 LAMB1 LTBP1 LTBP3

3.33e-0519982540de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

SPRY1 HMCN1 TNC LAMB1 LTBP1

3.33e-051998254bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellBiopsy_Control_(H.)-Mesenchymal-Myofibroblasts|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

HMCN1 TNC LAMB1 LTBP1 PRG4

3.33e-051998257a227c239afdaebcac84644d9b2653a5f1a4be71
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

SPRY1 TNC LRP1 LAMB1 LTBP1

3.33e-05199825211c3a08f2d484ab7a3368006767289088f0d957
Drugmonatepil

NETO1 LRP1 LRP2 SORL1

2.98e-0629794CID000060810
Diseasetriacylglycerol 58:12 measurement

NRXN3 WTIP MATN2

3.70e-0612773EFO_0010439
Diseasecongenital heart disease (implicated_via_orthology)

KMT2C KMT2B LRP2 KMT2A

3.26e-0569774DOID:1682 (implicated_via_orthology)
DiseaseNeurodevelopmental Disorders

KMT2C ZC3H4 KMT2A POGZ

1.05e-0493774C1535926
DiseaseCOVID-19 symptoms measurement

LIMD1 MUC5B MUC5AC

1.05e-0435773EFO_0600019
DiseaseNeoplasm of uncertain or unknown behavior of breast

ERBB4 BTK NOTCH2

1.70e-0441773C0496956
DiseaseCarcinoma, Transitional Cell

KMT2C KMT2A DAPK1

1.70e-0441773C0007138
DiseaseBreast adenocarcinoma

ERBB4 BTK NOTCH2

1.70e-0441773C0858252
Diseasepost-traumatic stress disorder

LHX2 TLL1 NOS1 ZMYM4 EGFEM1P

1.90e-04202775EFO_0001358
Diseasepulmonary fibrosis

MUC5B MUC5AC

3.64e-0411772EFO_0009448
DiseaseColorectal Carcinoma

KMT2C ZNF560 LRP1 LRP2 ZMYM4 EDRF1 PROS1 SORL1

4.89e-04702778C0009402
Diseasemethylcobalamin deficiency type cblE, response to antineoplastic agent

MATN2 KMT2A

5.15e-0413772GO_0097327, MONDO_0009354
Diseasecystic fibrosis (is_marker_for)

MUC5B NOS1 MUC5AC

5.78e-0462773DOID:1485 (is_marker_for)
Diseaseschizophrenia (biomarker_via_orthology)

ERBB4 ASH2L

6.90e-0415772DOID:5419 (biomarker_via_orthology)
Diseaseprostate cancer (is_marker_for)

KMT2C ERBB4 KMT2B KMT2A

7.54e-04156774DOID:10283 (is_marker_for)
DiseaseHereditary Diffuse Gastric Cancer

KMT2C POLR3K CHFR KMT2A NOTCH2

1.03e-03293775C1708349
DiseaseStomach Neoplasms

KMT2C POLR3K CHFR KMT2A NOTCH2

1.09e-03297775C0038356
DiseaseLeukemia, Myelocytic, Acute

KMT2C KMT2A DAPK1 NOTCH2

1.11e-03173774C0023467
DiseaseMalignant neoplasm of stomach

KMT2C POLR3K CHFR KMT2A NOTCH2

1.14e-03300775C0024623
Diseaseblood aluminium measurement

DAPK1 PXYLP1

1.24e-0320772EFO_0007575
DiseaseOsteoarthritis of hip

TNC LTBP3

1.24e-0320772C0029410
DiseaseFEV/FEC ratio

HMCN1 NETO1 LRP1 LTBP1 LTBP3 ARHGEF17 PRG4 USP3 FGF18 SORL1

1.31e-0312287710EFO_0004713
Diseasethyroxine measurement

LHX2 ERBB4 USP3

1.35e-0383773EFO_0005130
Diseasebody weight

ERBB4 NRXN3 SUSD1 TLL1 CHFR PXYLP1 LTBP1 LTBP3 FGF18 NEK11

1.59e-0312617710EFO_0004338
Diseasestomach carcinoma (is_marker_for)

KMT2C ERBB4

1.79e-0324772DOID:5517 (is_marker_for)
Diseasechronic obstructive pulmonary disease (is_marker_for)

MUC5B NOS1 MUC5AC

2.11e-0397773DOID:3083 (is_marker_for)
Diseasecytotoxicity measurement, response to clozapine

HMCN1 PRG4

2.61e-0329772EFO_0006952, GO_0097338
Diseasecolorectal cancer, overall survival

ERBB4 SORL1

2.61e-0329772EFO_0000638, MONDO_0005575

Protein segments in the cluster

PeptideGeneStartEntry
YFDDCMSIHQCKISC

TWSG1

171

Q9GZX9
CFACMNFNDSGACVT

ERBB4

246

Q15303
SIMCFGCHDVYSQAS

DAPK1

1281

P53355
QYLCCSQTAKNAMGC

BTK

151

Q06187
PCNEANHCCISKMYN

APOBEC4

126

Q8WW27
QCHEALFFNMGQCCC

ALDH1B1

306

P30837
SHDCFIYCCNMKGHL

AASDH

996

Q4L235
TDCYGCTALHYACEM

ANKRD22

131

Q5VYY1
CLPFMTNYSFHCNVC

ASH2L

136

Q9UBL3
MSYTSSYCRGVQCAC

NWD1

1426

Q149M9
YSAEAQAMQHQCTCC

MUC5B

5691

Q9HC84
PCEGNTFFCHSNMCI

NETO1

291

Q8TDF5
VTFCANNLVNHYMCD

OR8B8

166

Q15620
CLFCFQVCMLCSVGY

PAQR3

111

Q6TCH7
QVCMLCSVGYHLFSC

PAQR3

116

Q6TCH7
HMFYVGQDSSRCVAC

ARHGEF17

1851

Q96PE2
HGICMDGINRYSCVC

NOTCH2

656

Q04721
GCCHATMFFSICFSF

DCAF1

456

Q9Y4B6
QFFCTTCGQHYHGMC

KMT2C

356

Q8NEZ4
MCSTLEHNCAHFCIN

MATN2

241

O00339
CQAMGNLYHDTCFTC

LIMD1

486

Q9UGP4
QSHDTYCCLCTNMLS

EDRF1

721

Q3B7T1
HGNLCSMCQAYFQAE

SPINK5

326

Q9NQ38
RQCSGYCENFGTCQM

LRP1

4306

Q07954
GDCSNLEGSYMCSCH

LTBP1

1051

Q14766
MYSAPSACTCLCLHF

FGF18

1

O76093
FTCDCSMTSYSGNQC

NRXN3

1071

Q9Y4C0
YFNSCTMKSCCFAGD

DCAF5

276

Q96JK2
CCMNHAFAGSNFLSI

NEK11

226

Q8NG66
GECLNCQDYTMGHNC

LAMB1

881

P07942
CQDYTMGHNCERCLA

LAMB1

886

P07942
YHLNCFTCTTCNKML

LHX2

136

P50458
VGCCLSSCLSNFHFM

KMT2B

1651

Q9UMN6
SQHCYNMRGSFRCSC

LRP2

1401

P98164
YCQATMFECKNHVCI

LRP2

3841

P98164
CRCMHGGNCYFDETD

LRP2

4381

P98164
NMQYHECRSPCADTC

MUC5AC

341

P98088
GTYYSNCMFDTCNCE

MUC5AC

651

P98088
AGCQKSCHTLDMTCY

MUC5AC

821

P98088
HAYLKGDCVECMACS

MPI

276

P34949
ACQHECKNTFGSYQC

HMCN1

5441

Q96RW7
DCTTAHGMFNYICNH

NOS1

436

P29475
SLQPCMHTFCAACYS

CHFR

316

Q96EP1
AMSECTGCHKVNYCS

DEAF1

511

O75398
MDQCSCQFSYATCFR

FRMPD1

1331

Q5SYB0
LAVMADTFSCHCYQG

HYAL4

426

Q2M3T9
ICMNTGGSYNCHCNR

LTBP3

631

Q9NS15
MCGICCSVNFSAEHF

ASNSD1

1

Q9NWL6
CLTSCTSNYHFMCSR

KMT2A

1946

Q03164
MSYNCCSRNFSSCSH

KRTAP13-3

1

Q3SY46
MSYNCSSGNFSSCCF

KRTAP15-1

1

Q3LI76
MSYNCCCGNFSSHSC

KRTAP23-1

1

A1A580
VCQPMCSHAACYQSG

KRTAP29-1

81

A8MX34
IFGHNCSLSCKDCMN

EGFEM1P

16

Q0D2K5
ICVNAMGSYECQCHS

SCUBE1

131

Q8IWY4
MGSYECQCHSGFFLS

SCUBE1

136

Q8IWY4
ENCVYLHGDSCDMCG

MKRN1

226

Q9UHC7
ICIANGHCMNFSNAY

NR1D2

336

Q14995
GHCMNFSNAYTQRVC

NR1D2

341

Q14995
SHSMFCINICTVYCN

TAS2R39

171

P59534
GCAMNFTTLHCTYIN

SLC35D3

236

Q5M8T2
SHCEMHQCRSDEYNC

SORL1

1151

Q92673
HQCRSDEYNCSSGMC

SORL1

1156

Q92673
TCICYLCMFQEHKNH

TRIM29

241

Q14134
CQHECVNTMGSYMCQ

TLL1

741

O43897
TNVGEMKHYLCGCCA

SLC25A51

26

Q9H1U9
MKHYLCGCCAAFNNV

SLC25A51

31

Q9H1U9
YNCGEESLQSCMHFQ

NANOGP8

241

Q6NSW7
CRYSTCCSRAYANHM

POGZ

776

Q7Z3K3
DSMLCHFCHNVSFPC

PXYLP1

296

Q8TE99
CDHMTCSQCNTNFCY

RNF217

436

Q8TC41
TNVGEMKHYLCGCCA

SLC25A52

26

Q3SY17
MKHYLCGCCAAFNNV

SLC25A52

31

Q3SY17
SYHCSCKNGFVMLSN

PROS1

181

P07225
DATCNCDYNCQHYME

PRG4

41

Q92954
CDYNCQHYMECCPDF

PRG4

46

Q92954
SACLACFCANGHIMI

STXBP5L

991

Q9Y2K9
LFCDMCNLAVHQECY

BRPF1

291

P55201
SLMLQCGHSYCKGCL

TRIM74

26

Q86UV6
FNGIFSDHCYSVCSM

ZNF639

31

Q9UID6
NNKEAGMYHCVCCDS

MSRB2

81

Q9Y3D2
CANDLFYSMTCQHQE

NPVF

156

Q9HCQ7
CVNTHGSFECYCMDG

SUSD1

141

Q6UWL2
KGYDCSDMSCPNDCH

TNC

461

P24821
CMCLVKGIFYHCSND

SPRY1

221

O43609
MTTFYKCCNAQCGHR

POLR3K

91

Q9Y2Y1
YHTTGNCINGDDCMF

ZC3H4

451

Q9UPT8
QHTVCMDCSSYSTYC

USP3

81

Q9Y6I4
SLMLQCGHSYCKGCL

TRIM73

26

Q86UV7
QQACQAMGSLYHTDC

WTIP

236

A6NIX2
NFIMNCCENCGTYCY

ZMYM1

226

Q5SVZ6
DLHQNCPHCQVMYCS

SMYD5

106

Q6GMV2
LTMNCCENCGGYCYS

ZMYM4

481

Q5VZL5
CNACGNSFRNSMCFH

ZNF560

686

Q96MR9