Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	endopolyphosphatase activity	NUDT11 NUDT10	2.46e-04	5	100	2	GO:0000298
GeneOntologyMolecularFunction	bis(5'-adenosyl)-hexaphosphatase activity	NUDT11 NUDT10	2.46e-04	5	100	2	GO:0034431
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3C RIMBP3B	2.46e-04	5	100	2	GO:0030156
GeneOntologyMolecularFunction	diphosphoinositol-polyphosphate diphosphatase activity	NUDT11 NUDT10	2.46e-04	5	100	2	GO:0008486
GeneOntologyMolecularFunction	bis(5'-adenosyl)-pentaphosphatase activity	NUDT11 NUDT10	3.68e-04	6	100	2	GO:0034432
Domain	SPAR_C	SIPA1L3 SIPA1L2	8.32e-05	3	99	2	PF11881
Domain	SIPA1L_C	SIPA1L3 SIPA1L2	8.32e-05	3	99	2	IPR021818
Domain	CLTH	RMND5B RMND5A	4.11e-04	6	99	2	PF10607
Domain	CRA	RMND5B RMND5A	4.11e-04	6	99	2	SM00757
Domain	CTLH/CRA	RMND5B RMND5A	4.11e-04	6	99	2	IPR024964
Domain	CRA_dom	RMND5B RMND5A	4.11e-04	6	99	2	IPR013144
Domain	-	LAMC3 F8 GUSB EPHA3	6.11e-04	73	99	4	2.60.120.260
Domain	CTLH	RMND5B RMND5A	9.77e-04	9	99	2	SM00668
Domain	CTLH_C	RMND5B RMND5A	1.22e-03	10	99	2	IPR006595
Domain	Rap_GAP	SIPA1L3 SIPA1L2	1.22e-03	10	99	2	PF02145
Domain	CTLH	RMND5B RMND5A	1.22e-03	10	99	2	PS50897
Domain	Growth_fac_rcpt_	LAMC3 SLIT3 LTBP2 RSPO1 EPHA3	1.45e-03	156	99	5	IPR009030
Domain	Rap_GAP_dom	SIPA1L3 SIPA1L2	1.48e-03	11	99	2	IPR000331
Domain	Ephrin_rec_like	TG EPHA3	1.48e-03	11	99	2	PF07699
Domain	RAPGAP	SIPA1L3 SIPA1L2	1.48e-03	11	99	2	PS50085
Domain	Galactose-bd-like	LAMC3 F8 GUSB EPHA3	1.57e-03	94	99	4	IPR008979
Domain	NUDIX_hydrolase_CS	NUDT11 NUDT10	1.77e-03	12	99	2	IPR020084
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	ADAMTS1 LARS1 SMPD4 SSH1 SEMA6A STAMBPL1 SIPA1L2 MRTFA	1.67e-08	153	101	8	10718198
Pubmed	Human transcription factor protein interaction networks.	TSHZ3 CNOT10 LARS1 ETV5 C15orf39 BCL11A NUP54 MFAP1 ALMS1 NKX2-5 HAL HERC1 PCCA TRAPPC9 PCM1 INO80B	3.60e-06	1429	101	16	35140242
Pubmed	A comparative gene map of the horse (Equus caballus).	TG GUSB PRKDC	5.13e-06	12	101	3	10613847
Pubmed	Brain glycogen serves as a critical glucosamine cache required for protein glycosylation.	EPM2A AGL	8.35e-06	2	101	2	34043942
Pubmed	Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases.	NUDT11 NUDT10	8.35e-06	2	101	2	12689335
Pubmed	COX-2 Induces Breast Cancer Stem Cells via EP4/PI3K/AKT/NOTCH/WNT Axis.	GUSB PRKDC	8.35e-06	2	101	2	27301070
Pubmed	VEGF and PlGF promote adult vasculogenesis by enhancing EPC recruitment and vessel formation at the site of tumor neovascularization.	GUSB PRKDC	8.35e-06	2	101	2	16754748
Pubmed	An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase.	NUDT11 NUDT10	8.35e-06	2	101	2	12105228
Pubmed	Engraftment of human CD34+ cells leads to widespread distribution of donor-derived cells and correction of tissue pathology in a novel murine xenotransplantation model of lysosomal storage disease.	GUSB PRKDC	8.35e-06	2	101	2	12406886
Pubmed	ERM/ETV5 up-regulation plays a role during myometrial infiltration through matrix metalloproteinase-2 activation in endometrial cancer.	ETV5 MMP2	8.35e-06	2	101	2	17638886
Pubmed	Residues essential for plasminogen binding by the cation-independent mannose 6-phosphate receptor.	GUSB PLG	8.35e-06	2	101	2	20028034
Pubmed	Plasmin triggers chemotaxis of monocyte-derived dendritic cells through an Akt2-dependent pathway and promotes a T-helper type-1 response.	AKT2 PLG	8.35e-06	2	101	2	20056908
Pubmed	MKL1 links epigenetic activation of MMP2 to ovarian cancer cell migration and invasion.	MMP2 MRTFA	8.35e-06	2	101	2	28385531
Pubmed	ETV5 as a regulator of matrix metalloproteinase 2 in human chondrosarcoma.	ETV5 MMP2	8.35e-06	2	101	2	22968857
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	MAP4 LARS1 MCM7 AGL PRKDC RPL17	1.44e-05	179	101	6	36261009
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SEC16B MAP4 GPRIN1 MFAP1 MYO3A RBMXL2 SSH1 TRAPPC10 PRKDC PCM1 MRTFA	1.60e-05	774	101	11	15302935
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	ZFYVE16 SMPD4 PTPN9 ATRIP GUSB TRAPPC10 TRAPPC9	2.06e-05	285	101	7	34369648
Pubmed	PLPP/CIN regulates bidirectional synaptic plasticity via GluN2A interaction with postsynaptic proteins.	GRIN2A PDXP	2.50e-05	3	101	2	27212638
Pubmed	MiR-338-5p Promotes Glioma Cell Invasion by Regulating TSHZ3 and MMP2.	TSHZ3 MMP2	2.50e-05	3	101	2	28780604
Pubmed	RapGAPs in brain: multipurpose players in neuronal Rap signalling.	SIPA1L3 SIPA1L2	2.50e-05	3	101	2	20576033
Pubmed	In vivo analysis of protein kinase B (PKB)/Akt regulation in DNA-PKcs-null mice reveals a role for PKB/Akt in DNA damage response and tumorigenesis.	AKT2 PRKDC	2.50e-05	3	101	2	18757368
Pubmed	Skin wound healing in MMP2-deficient and MMP2 / plasminogen double-deficient mice.	MMP2 PLG	2.50e-05	3	101	2	20163454
Pubmed	Interaction between cancer cells and stromal fibroblasts is required for activation of the uPAR-uPA-MMP-2 cascade in pancreatic cancer metastasis.	MMP2 PLG	2.50e-05	3	101	2	17545513
Pubmed	Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases.	NUDT11 NUDT10	2.50e-05	3	101	2	12121577
Pubmed	The Wnt modulator sFRP2 enhances mesenchymal stem cell engraftment, granulation tissue formation and myocardial repair.	GUSB PRKDC	2.50e-05	3	101	2	19017790
Pubmed	Variation in 24 hemostatic genes and associations with non-fatal myocardial infarction and ischemic stroke.	F8 PLG	2.50e-05	3	101	2	17927806
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TSHZ3 ZFYVE16 C15orf39 MCM7 ALMS1 PCCA PCM1 MRTFA	3.11e-05	418	101	8	34709266
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	CNOT10 SIPA1L3 ALMS1 TRAPPC10 PRKDC SIPA1L2 TRAPPC9 PCM1	4.90e-05	446	101	8	24255178
Pubmed	Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling.	MCM7 ATRIP	4.99e-05	4	101	2	15538388
Pubmed	Suppression of PKC-α attenuates TNF-α-evoked cerebral barrier breakdown via regulations of MMP-2 and plasminogen-plasmin system.	MMP2 PLG	4.99e-05	4	101	2	27094771
Pubmed	Matrix metalloproteinase-2 and matrix metalloproteinase-9 codistribute with transcription factors RUNX1/AML1 and ETV5/ERM at the invasive front of endometrial and ovarian carcinoma.	ETV5 MMP2	4.99e-05	4	101	2	20970160
Pubmed	Nuclear localization of p38 MAPK in response to DNA damage.	PRKDC MAP2K6	4.99e-05	4	101	2	19564926
Pubmed	Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate.	NUDT11 NUDT10	4.99e-05	4	101	2	12370170
Pubmed	mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes.	AKT2 PRKDC	4.99e-05	4	101	2	16221682
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3C RIMBP3B	4.99e-05	4	101	2	19091768
Pubmed	The carbohydrate-binding domain of overexpressed STBD1 is important for its stability and protein-protein interactions.	EPM2A AGL	4.99e-05	4	101	2	24837458
Pubmed	Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapy.	EPM2A PRKDC	4.99e-05	4	101	2	24209604
Pubmed	Proteolytic cleavage of versican during limb joint development.	ADAMTS1 MMP2	4.99e-05	4	101	2	20101710
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FAM47A GFRAL GPRIN1 IGSF10 SRGAP3 AGL AGTR2 PRKDC MMP2 MEGF10	5.77e-05	736	101	10	29676528
Pubmed	Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.	SRGAP3 SLIT3 SEMA6A	7.39e-05	28	101	3	18617019
Pubmed	Akt1-Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration.	ETV5 AKT2	8.30e-05	5	101	2	27938661
Pubmed	Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation and neuronal cofilin-actin rod formation.	SSH1 PDXP	8.30e-05	5	101	2	19000834
Pubmed	Effect of angiotensin II on primary cardiac fibroblast matrix metalloproteinase activities.	AGTR2 MMP2	8.30e-05	5	101	2	17633135
Pubmed	Regulators of tubulin polyglutamylation control nuclear shape and cilium disassembly by balancing microtubule and actin assembly.	MAP4 PCM1	8.30e-05	5	101	2	34782749
Pubmed	Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer.	NUDT11 NUDT10	8.30e-05	5	101	2	18264098
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3C RIMBP3B	8.30e-05	5	101	2	17855024
Pubmed	MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells.	MMP2 PLG	8.30e-05	5	101	2	16147977
Pubmed	Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase.	LARS1 ZCRB1 PRKDC PCM1	8.52e-05	79	101	4	29121065
Pubmed	Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction.	ADAMTS1 NKX2-5 MMP2	1.11e-04	32	101	3	31434798
Pubmed	Myc is dispensable for cardiomyocyte development but rescues Mycn-deficient hearts through functional replacement and cell competition.	NKX2-5 PCM1	1.24e-04	6	101	2	30642836
Pubmed	Proteolytic cleavage of versican during cardiac cushion morphogenesis.	ADAMTS1 MMP2	1.24e-04	6	101	2	16691565
Pubmed	Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases.	MCM7 ATRIP	1.24e-04	6	101	2	15210935
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	EPM2A ZFYVE16 ACP1 ATL3 PTPN9 SSH1 AGL PRKDC SIPA1L2 PCM1 RPL17	1.26e-04	974	101	11	28675297
Pubmed	Increased expression of HIF-1alpha, VEGF-A and its receptors, MMP-2, TIMP-1, and ADAMTS-1 at the venous stenosis of arteriovenous fistula in a mouse model with renal insufficiency.	ADAMTS1 MMP2	1.74e-04	7	101	2	20598569
Pubmed	Tissue-Specific Roles for the Slit-Robo Pathway During Heart, Caval Vein, and Diaphragm Development.	SLIT3 NKX2-5	1.74e-04	7	101	2	35343246
Pubmed	MT1-MMP-dependent neovessel formation within the confines of the three-dimensional extracellular matrix.	MMP2 PLG	1.74e-04	7	101	2	15545316
Pubmed	Centrosomal localization of DNA damage checkpoint proteins.	ATRIP PRKDC	1.74e-04	7	101	2	17171639
Pubmed	Ypt1 recruits the Atg1 kinase to the preautophagosomal structure.	TRAPPC10 TRAPPC9	1.74e-04	7	101	2	23716696
Pubmed	Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults.	ADAMTS1 MMP2	1.74e-04	7	101	2	23354118
Pubmed	Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis.	ADAMTS1 NKX2-5 MMP2	1.86e-04	38	101	3	18267097
Pubmed	Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction.	PRKDC PCM1	2.31e-04	8	101	2	29946151
Pubmed	Deletion of Akt1 causes heart defects and abnormal cardiomyocyte proliferation.	NKX2-5 AKT2	2.31e-04	8	101	2	20816796
Pubmed	A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease.	EPM2A AGL	2.31e-04	8	101	2	17908927
Pubmed	High-resolution genetic analysis of a deletion on mouse chromosome 17 extending over the fused, tufted, and homeobox Nkx2-5 loci.	NKX2-5 PLG	2.31e-04	8	101	2	7894168
Pubmed	Functional interdependence at the chromatin level between the MKK6/p38 and IGF1/PI3K/AKT pathways during muscle differentiation.	AKT2 MAP2K6	2.31e-04	8	101	2	17964260
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	FAM120B MAP4 SIPA1L3 LARS1 BCL11A GRIN2A WASHC5 SRGAP3 TRAPPC10 SIPA1L2 TRAPPC9 PCM1 RPL17	2.59e-04	1431	101	13	37142655
Pubmed	Typing recombinant inbred mouse strains for microsatellite markers.	TG HAL	2.97e-04	9	101	2	8507976
Pubmed	DNA-PKcs, but not TLR9, is required for activation of Akt by CpG-DNA.	AKT2 PRKDC	2.97e-04	9	101	2	15678105
Pubmed	Semaphorin 6A in Retinal Ganglion Cells Regulates Functional Specialization of the Inner Retina.	SEMA6A MEGF10	2.97e-04	9	101	2	38014224
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	ZFYVE16 MAP4 CNOT10 LARS1 SMPD4 PRKDC RPL17	3.46e-04	449	101	7	31732153
Pubmed	Analyses of shared genetic factors between asthma and obesity in children.	SEC16B ACP1 ETV5	3.51e-04	47	101	3	20816195
Pubmed	Real-time resolution of point mutations that cause phenovariance in mice.	KBTBD2 PRKDC	3.70e-04	10	101	2	25605905
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	POLG SIPA1L3 C15orf39 LAMC3 SSH1 ZNF500 AKT2 PRKDC HERC1 SIPA1L2 TRAPPC9	3.71e-04	1105	101	11	35748872
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ZFYVE16 MAP4 LARS1 GPRIN1 ALMS1 PRKDC SIPA1L2 PCCA PCM1 RPL17	3.94e-04	934	101	10	33916271
Pubmed	Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies.	SEC16B ETV5	4.51e-04	11	101	2	19812171
Pubmed	Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.	ATRIP PRKDC	4.51e-04	11	101	2	15758953
Pubmed	Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome.	TRAPPC10 TRAPPC9	4.51e-04	11	101	2	21273506
Pubmed	MRE11 complex links RECQ5 helicase to sites of DNA damage.	MCM7 PRKDC	4.51e-04	11	101	2	19270065
Pubmed	Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.	TG GPR174	4.51e-04	11	101	2	23612905
Pubmed	Multiple newly identified loci associated with prostate cancer susceptibility.	NUDT11 NUDT10	4.51e-04	11	101	2	18264097
Pubmed	Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma.	ETV5 MMP2	4.51e-04	11	101	2	28827401
Pubmed	DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169.	CNOT10 SIPA1L3 FAM117B SIPA1L2	4.53e-04	122	101	4	30773093
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	ZFYVE16 MAP4 LAMC3 GPRIN1 PCCA	5.29e-04	226	101	5	31452512
Pubmed	The IL-2 receptor beta chain gene (Il-2rb) is closely linked to the Pdgfb locus on mouse chromosome 15.	TG HAL MLPH	5.29e-04	54	101	3	8482578
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	MAP4 GRIN2A GPRIN1 SRGAP3 SIPA1L2 PCM1	5.40e-04	347	101	6	17114649
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	ADAMTS1 MCM7 FAM117B NUP54 PRKDC SIPA1L2 PCM1 RPL17	5.62e-04	639	101	8	23443559
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	MAP4 ATL3 SMPD4 MCM7 GPRIN1 WASHC5 AGL NUDT10 PRKDC HAL PCCA RPL17	6.14e-04	1367	101	12	32687490
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	ZFYVE16 MAP4 AKT2 PCM1	6.26e-04	133	101	4	15144186
Pubmed	Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models.	TG PRKDC	6.38e-04	13	101	2	22724066
Pubmed	Expression of Slit and Robo genes in the developing mouse heart.	SLIT3 NKX2-5	6.38e-04	13	101	2	20941780
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	SEC16B EPM2A MAP4 ABCA13 SIPA1L3 PRKDC	6.64e-04	361	101	6	26167880
Pubmed	Generation and analysis of 280,000 human expressed sequence tags.	SEC16B DUS4L RNF19B SMPD4 ZNF500 RPL17	7.34e-04	368	101	6	8889549
Pubmed	Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.	SEC16B ETV5	7.43e-04	14	101	2	19851340
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3C RIMBP3B	7.43e-04	14	101	2	17662146
Pubmed	Subcellular localization of intracellular protein tyrosine phosphatases in T cells.	ACP1 PTPN9	7.43e-04	14	101	2	10940933
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	MAP4 MFAP1 NUDT11 NUDT10 PCM1	7.75e-04	246	101	5	15345747
Pubmed	Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.	SEC16B GPRIN1 TRAPPC9	8.32e-04	63	101	3	11572484
Pubmed	Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese.	SEC16B ETV5	8.55e-04	15	101	2	20215397
Pubmed	TRAPP Complexes in Secretion and Autophagy.	TRAPPC10 TRAPPC9	8.55e-04	15	101	2	27066478
Pubmed	Generation of a floxed allele of Smad5 for cre-mediated conditional knockout in the mouse.	NKX2-5 AKT2	8.55e-04	15	101	2	14502571
Cytoband	Ensembl 112 genes in cytogenetic band chr5q35	RMND5B GPRIN1 PRR7 SLIT3 NKX2-5	1.79e-04	235	101	5	chr5q35
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMC3 IGSF10 MFAP1 SLIT3 LTBP2 RSPO1 OTOG	8.83e-06	191	100	7	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMC3 IGSF10 MFAP1 SLIT3 LTBP2 RSPO1 OTOG	1.05e-05	196	100	7	M3008
Coexpression	GSE27786_CD8_TCELL_VS_NEUTROPHIL_DN	RMND5B EPM2A GAS2L3 MYO3A PTPN9 TRAPPC10 AKT2	1.15e-05	199	100	7	M4847
ToppCell	-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	HIF3A IGSF10 SLIT3 LTBP2 MMP2 RSPO1 EPHA3	1.76e-07	179	101	7	10fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ADAMTS1 HIF3A IGSF10 SLIT3 LTBP2 MMP2 EPHA3	3.73e-07	200	101	7	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ADAMTS1 HIF3A IGSF10 SLIT3 LTBP2 MMP2 EPHA3	3.73e-07	200	101	7	a510deaada669e690329183e18df02870bd204b3
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADAMTS1 HIF3A IGSF10 SLIT3 LTBP2 MMP2 EPHA3	3.73e-07	200	101	7	dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSHZ3 LAMC3 F8 IGSF10 AGTR2 MMP2	2.34e-06	168	101	6	d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ3 TEX15 SLIT3 AGTR2 LTBP2 EPHA3	2.97e-06	175	101	6	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	Fibroblast-C\|World / shred on cell class and cell subclass (v4)	TSHZ3 SLIT3 AGTR2 LTBP2 MMP2 RSPO1	4.62e-06	189	101	6	58e0400fbab5a0755504275aef5cf7986149abab
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSHZ3 IGSF10 SLIT3 AGTR2 LTBP2 MMP2	5.06e-06	192	101	6	ad48c941a3ddfd9a5146bafc2209da577bb50531
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGSF10 SLIT3 LTBP2 MMP2 RSPO1 EPHA3	5.06e-06	192	101	6	c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TSHZ3 ETV5 SRGAP3 SLIT3 MMP2 PCCA	5.52e-06	195	101	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 IGSF10 SLIT3 LTBP2 MMP2 EPHA3	5.69e-06	196	101	6	9737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 B4GALT1 NUDT11 SLIT3 SEMA6A MMP2	5.69e-06	196	101	6	46d665de09f8164690b9a3e0acf0b0afa3f81b3d
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 IGSF10 SLIT3 LTBP2 MMP2 EPHA3	5.86e-06	197	101	6	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTS1 IGSF10 SLIT3 LTBP2 MMP2 RSPO1	6.03e-06	198	101	6	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS1 IGSF10 SLIT3 LTBP2 MMP2 RSPO1	6.21e-06	199	101	6	28c1722deef3b8347371c7359be7c64b95780de3
ToppCell	(5)_Fibroblast-G\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ADAMTS1 HIF3A IGSF10 SLIT3 LTBP2 MMP2	6.21e-06	199	101	6	b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTS1 IGSF10 SLIT3 LTBP2 MMP2 RSPO1	6.21e-06	199	101	6	66a79732caf2f04c09b4d9832377aa01ca477677
ToppCell	343B-Fibroblasts-Fibroblast-G\|343B / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS1 IGSF10 SLIT3 LTBP2 MMP2 RSPO1	6.21e-06	199	101	6	f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell	343B-Fibroblasts-Fibroblast-G-\|343B / Donor, Lineage, Cell class and subclass (all cells)	ADAMTS1 IGSF10 SLIT3 LTBP2 MMP2 RSPO1	6.21e-06	199	101	6	9c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Prlr-Inhibitory_Gad1Gad2_Id2.Prlr_(Interneuron,_Neurogliaform3)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GFRAL TG MYO3A AGTR2	7.47e-06	55	101	4	948f26841f18d2d45f74c7c0c7b5be10737a4f43
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Prlr\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GFRAL TG MYO3A AGTR2	7.47e-06	55	101	4	616be3c334949ab0264293b9771d494381d74fb4
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Prlr-Inhibitory_Gad1Gad2_Id2.Prlr_(Interneuron,_Neurogliaform3)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GFRAL TG MYO3A AGTR2	7.47e-06	55	101	4	ed14bdb80cf2ff171b0dfc391ac0b150da344992
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LAMC3 SLIT3 PRKDC MMP2 EPHA3	1.94e-05	144	101	5	1c001a5a3bbe4ecbce8305f8b260e933033550dd
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM120B DUS4L C15orf39 SRGAP3 TRAPPC9	4.06e-05	168	101	5	b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEC16B LAMC3 AGTR2 MMP2 PLG	4.17e-05	169	101	5	031465190cd3623a25ef2b868daab8d932c8ff08
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEC16B LAMC3 AGTR2 MMP2 PLG	4.41e-05	171	101	5	15cb4670ff4234ac46aea8a5911138d6913c4482
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 GRIN2A SLIT3 NUDT10 EPHA3	4.54e-05	172	101	5	1ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 GRIN2A SLIT3 NUDT10 EPHA3	4.54e-05	172	101	5	ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCell	-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS1 LAMC3 SLIT3 LTBP2 MMP2	4.66e-05	173	101	5	88be9182fbb1bc83531cd41e59ea57c112a21d54
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCM7 BCL11A TG ALMS1 SRGAP3	4.66e-05	173	101	5	6c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	GAS2L3 ADAMTS1 ETV5 SEMA6A SIPA1L2	4.79e-05	174	101	5	fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	LAMC3 AGTR2 LTBP2 MMP2 MEGF10	5.93e-05	182	101	5	812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS1 LRSAM1 LAMC3 SLIT3 EPHA3	6.41e-05	185	101	5	e1fbec55b71f604189eb2431768fadbaa0453a83
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS1 LRSAM1 LAMC3 SLIT3 EPHA3	6.41e-05	185	101	5	9d933cd5ebc8368fd37aa83113d2dfa6938ff72d
ToppCell	Control-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	TSHZ3 BCL11A HIF3A TG LTBP2	6.41e-05	185	101	5	d5d6d13e2f20b54ca55645b9a757b8599f4fd897
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 IGSF10 SLIT3 LTBP2 MMP2	6.57e-05	186	101	5	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TSHZ3 LTBP2 MMP2 MEGF10 EPHA3	6.57e-05	186	101	5	e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 IGSF10 SLIT3 RSPO1 EPHA3	6.74e-05	187	101	5	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 IGSF10 SLIT3 RSPO1 EPHA3	6.74e-05	187	101	5	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 IGSF10 SLIT3 RSPO1 EPHA3	6.74e-05	187	101	5	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	normal-na-Hematopoietic-progenitor_cell\|normal / PBMC cell types (v2) per disease, treatment status, and sex	BCO1 IGSF10 NUDT10 KEL MMP2	6.91e-05	188	101	5	013162466a3334b6967c0cb670c8577d809b1396
ToppCell	normal-na-Hematopoietic-progenitor_cell-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	BCO1 IGSF10 NUDT10 KEL MMP2	6.91e-05	188	101	5	be25371e6459504b5f0c9ece3a0fe8f80c7824ca
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HIF3A IGSF10 SRGAP3 SLIT3 MMP2	7.09e-05	189	101	5	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS1 IGSF10 SLIT3 MMP2 EPHA3	7.82e-05	193	101	5	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TSHZ3 ETV5 SRGAP3 SLIT3 PCCA	8.02e-05	194	101	5	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMC3 SLIT3 LTBP2 MMP2 RSPO1	8.02e-05	194	101	5	02b8102be9414d6964cd71019613edff6d88b893
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TSHZ3 HIF3A SRGAP3 SLIT3 MMP2	8.02e-05	194	101	5	8c37bedb23285735ff3828db3889897fada8c95d
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS1 IGSF10 SLIT3 MMP2 EPHA3	8.02e-05	194	101	5	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS1 HIF3A B4GALT1 SLIT3 MMP2	8.21e-05	195	101	5	ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell	ASK428-Mesenchymal\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	LAMC3 SLIT3 LTBP2 MMP2 EPHA3	8.21e-05	195	101	5	2b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGSF10 SLIT3 LTBP2 MMP2 EPHA3	8.21e-05	195	101	5	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 IGSF10 SLIT3 LTBP2 MMP2	8.21e-05	195	101	5	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	ASK428-Mesenchymal-Fibroblast\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	LAMC3 SLIT3 LTBP2 MMP2 EPHA3	8.21e-05	195	101	5	c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCell	PCW_05-06-Mesenchymal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TSHZ3 HIF3A SLIT3 MMP2 EPHA3	8.41e-05	196	101	5	dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLIT3 LTBP2 MMP2 RSPO1 EPHA3	8.41e-05	196	101	5	e7bfd4fb400ae0c473131d0fa306c26be08a6d03
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLIT3 LTBP2 MMP2 RSPO1 EPHA3	8.41e-05	196	101	5	82fad623212d986a7fca3496faf3f8c8f5b83a11
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLIT3 LTBP2 MMP2 RSPO1 EPHA3	8.41e-05	196	101	5	85e5046f774537684e1443c0fc147d562b7068d0
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 IGSF10 SLIT3 LTBP2 MMP2	8.41e-05	196	101	5	cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell	distal-mesenchymal-Lipofibroblast-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS1 NUDT11 SLIT3 NUDT10 MMP2	8.62e-05	197	101	5	865010edcd7e3f79f505fcef7b33882095994aa8
ToppCell	distal-mesenchymal-Lipofibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS1 NUDT11 SLIT3 NUDT10 MMP2	8.62e-05	197	101	5	ceb83bdef16b58ee16193413bfb006f7715728b2
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|normal_Lung / Location, Cell class and cell subclass	IGSF10 SLIT3 LTBP2 MMP2 RSPO1	8.62e-05	197	101	5	6c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCell	background-Hepatic_Stellate_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	ADAMTS1 LAMC3 LTBP2 MMP2 EPHA3	8.83e-05	198	101	5	bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell	5'-Parenchyma_lung-Mesenchymal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 LAMC3 SLIT3 LTBP2 MMP2	8.83e-05	198	101	5	aae663c6da70b6e716edeed50cc7d3962d78e697
ToppCell	proximal-mesenchymal-Alveolar_Fibroblast\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IGSF10 SLIT3 LTBP2 MMP2 RSPO1	9.04e-05	199	101	5	7f4840ae6a888380feca722543e5e52783f3e35d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LAMC3 SLIT3 LTBP2 MMP2 MLPH	9.04e-05	199	101	5	dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCell	proximal-3-mesenchymal-Alveolar_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IGSF10 SLIT3 LTBP2 MMP2 RSPO1	9.04e-05	199	101	5	301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCell	ASK452-Mesenchymal-Fibroblast\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	ADAMTS1 LAMC3 SLIT3 LTBP2 MMP2	9.04e-05	199	101	5	4d0bf2a4bd97e5a3bfe4570a201cc21bb9c4c1f6
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	TEX15 IGSF10 SLIT3 STAMBPL1 MMP2	9.04e-05	199	101	5	c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCell	proximal-mesenchymal-Alveolar_Fibroblast-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IGSF10 SLIT3 LTBP2 MMP2 RSPO1	9.04e-05	199	101	5	9a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCell	ASK452-Mesenchymal\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	ADAMTS1 LAMC3 SLIT3 LTBP2 MMP2	9.04e-05	199	101	5	93e85e3731a9ece9aee3eb82c5dfdad331ee62d6
ToppCell	Tracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 LTBP2 MMP2 RSPO1 EPHA3	9.04e-05	199	101	5	e9009eee7f77b9c9917f8e0e723001d9e76eb553
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SLIT3 LTBP2 MMP2 RSPO1 EPHA3	9.04e-05	199	101	5	e1f1950d6f840485e263b83dc81b98910be3ae7a
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IGSF10 SLIT3 LTBP2 MMP2 RSPO1	9.04e-05	199	101	5	fb23ecce41e31e2cc01814e3c0add756f489561f
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGSF10 SLIT3 LTBP2 MMP2 EPHA3	9.04e-05	199	101	5	0019cfaa586a450c2e4952d1184a540561c8d0ba
ToppCell	distal-mesenchymal-Alveolar_Fibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IGSF10 SLIT3 LTBP2 MMP2 RSPO1	9.04e-05	199	101	5	655d07cf9a2fd9b945a2ed4f824cba0297de72a8
ToppCell	distal-1-mesenchymal-Lipofibroblast\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS1 NUDT11 SLIT3 SEMA6A MMP2	9.04e-05	199	101	5	a8293db3c42a8d30897858b49aae7acfc18663ba
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LAMC3 SLIT3 LTBP2 MMP2 MLPH	9.04e-05	199	101	5	c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCell	medial-2-mesenchymal\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS1 LAMC3 SLIT3 LTBP2 MMP2	9.25e-05	200	101	5	a9d8aa5bcf383d98a9e2eaf4b1f8466982d6b088
ToppCell	cellseq-Mesenchymal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTS1 LAMC3 SLIT3 LTBP2 MMP2	9.25e-05	200	101	5	238285fc372ce2e5e4341fc3084a3a833bf4a0a6
ToppCell	medial-mesenchymal-Alveolar_Fibroblast\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS1 IGSF10 SLIT3 LTBP2 MMP2	9.25e-05	200	101	5	c22cbfecee00183dd4be678f116ab9fd9ad0a4dd
ToppCell	distal-mesenchymal\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS1 LAMC3 SLIT3 LTBP2 MMP2	9.25e-05	200	101	5	b54137a4545690f51e154bb05964eaa650c3ca8e
ToppCell	distal-2-mesenchymal-Alveolar_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IGSF10 SLIT3 LTBP2 MMP2 RSPO1	9.25e-05	200	101	5	12b705dabec1b3752a488a891eda1a5123fcdc41
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	TEX15 IGSF10 SLIT3 STAMBPL1 MMP2	9.25e-05	200	101	5	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RMND5B ASAP3 SLIT3 LTBP2 EPHA3	9.25e-05	200	101	5	36de49593cf6ff1c9229fcceb150c1d68658a360
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LAMC3 LTBP2 MMP2 RSPO1 EPHA3	9.25e-05	200	101	5	8ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCell	distal-2-mesenchymal\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS1 LAMC3 SLIT3 LTBP2 MMP2	9.25e-05	200	101	5	65a50f03b0027ccefb51b8f77afa283d4a3b3567
ToppCell	medial-2-mesenchymal-Alveolar_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS1 IGSF10 SLIT3 LTBP2 MMP2	9.25e-05	200	101	5	cc6062dac07916c29091fc6bee2b864d29e6525b
ToppCell	medial-mesenchymal-Alveolar_Fibroblast-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS1 IGSF10 SLIT3 LTBP2 MMP2	9.25e-05	200	101	5	5c0716bf375c8158f7dc2c82bf5eaf37af594dd0
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	LAMC3 SLIT3 LTBP2 MMP2 RSPO1	9.25e-05	200	101	5	16a3685c41194a0a4a772e4eee372160263480e0
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	TEX15 IGSF10 SLIT3 STAMBPL1 MMP2	9.25e-05	200	101	5	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	medial-mesenchymal\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAMTS1 LAMC3 SLIT3 LTBP2 MMP2	9.25e-05	200	101	5	4f19e1e40966e27779bf77e8c170ed3ecc24353e
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TSHZ3 LTBP2 MMP2 RSPO1 EPHA3	9.25e-05	200	101	5	fb53be20392a8309a7393774c774a1b1aec6e676
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	TEX15 IGSF10 SLIT3 STAMBPL1 MMP2	9.25e-05	200	101	5	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Serpinf1-Serpinf1_Clrn1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TEX15 IGSF10 LTBP2 EPHA3	1.51e-04	118	101	4	702548d8187d54e8814375e5ae7609631fc71d5f
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Gad2-Inhibitory_Neuron.Gad1Gad2.Gad2-Kcnc3_(GABAergic,_K/Na_Channel_State)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	BCO1 MYO3A PLG	2.37e-04	53	101	3	a58b0b1c9991cfebf20e206a129b79f494785138
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Gad2-Inhibitory_Neuron.Gad1Gad2.Gad2-Kcnc3_(GABAergic,_K/Na_Channel_State)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	BCO1 MYO3A PLG	2.37e-04	53	101	3	e90685a7c6ef223783b1c1a6b1896fd566449422
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Gad2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	BCO1 MYO3A PLG	2.37e-04	53	101	3	5ad1a5c5c9a1dc66dd7e6de6edbee0176678966c
ToppCell	PND01-03-samps-Mesenchymal-Pericyte-pericyte_E\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	APOM AGL LTBP2 OTOG	2.53e-04	135	101	4	35928195cf34f055b353562c96f451aef2344d64
ToppCell	LPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TEX15 MYO3A ZNF500 KEL	2.67e-04	137	101	4	8e2fa2ef8becace96a68bb85c002329110902fbb
ToppCell	facs-Heart-Unknown-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIF3A TEX15 NUDT11 HAL	3.06e-04	142	101	4	759fbbd15b4fb313bd6269b7f087edafebd530ef
Drug	Tranexamic acid [1197-18-8]; Up 200; 25.4uM; MCF7; HT_HG-U133A	ELOA2 MAP4 ASAP3 BCL11A BCO1 TG AGBL2 MRTFA	2.38e-06	197	99	8	2248_UP
Drug	Nitrofurantoin [67-20-9]; Up 200; 16.8uM; HL60; HT_HG-U133A	RMND5A ADAMTS1 MAP4 SIPA1L3 RNF19B ETV5 LAMC3 INO80B	2.57e-06	199	99	8	2341_UP
Drug	prinomastat	EPM2A ETV5 PRKDC MMP2	1.25e-05	33	99	4	CID000466151
Drug	adenosine 5'-tetraphosphate	NUDT11 NUDT10	1.87e-05	2	99	2	ctd:C017991
Drug	diadenosine 5',5''''-P1,P6-hexaphosphate	NUDT11 NUDT10	1.87e-05	2	99	2	ctd:C070070
Drug	adenosine 5'-pentaphosphate	NUDT11 NUDT10	1.87e-05	2	99	2	ctd:C048567
Drug	Enalapril maleate [76095-16-4]; Down 200; 8.2uM; HL60; HT_HG-U133A	MAP4 SIPA1L3 RNF19B HIF3A LTBP2 PCCA INO80B	2.25e-05	194	99	7	2397_DN
Drug	Chlorzoxazone [95-25-0]; Up 200; 23.6uM; MCF7; HT_HG-U133A	RMND5A SIPA1L3 ETV5 TEX15 SRGAP3 KEL HAL	2.40e-05	196	99	7	2263_UP
Drug	Trioxsalen [3902-71-4]; Down 200; 17.6uM; HL60; HT_HG-U133A	MAP4 SIPA1L3 RNF19B TECPR2 TRAPPC10 HAL MRTFA	2.40e-05	196	99	7	2516_DN
Drug	Diazoxide [364-98-7]; Down 200; 17.4uM; PC3; HT_HG-U133A	MAP4 SIPA1L3 ASAP3 BCL11A TRAPPC10 PCCA TRAPPC9	2.48e-05	197	99	7	2052_DN
Drug	Doxepin hydrochloride [1229-29-4]; Down 200; 12.6uM; HL60; HT_HG-U133A	MAP4 DUS4L HIF3A LTBP2 PCCA TRAPPC9 INO80B	2.48e-05	197	99	7	2384_DN
Drug	quercetin dihydrate; Down 200; 1uM; MCF7; HT_HG-U133A_EA	EPM2A MAP4 POLG RNF19B ALMS1 TECPR2 ZNF500	2.56e-05	198	99	7	917_DN
Drug	Sulfapyridine [144-83-2]; Down 200; 16uM; HL60; HT_HG-U133A	EPM2A RMND5A MAP4 SIPA1L3 F8 B4GALT1 INO80B	2.56e-05	198	99	7	2538_DN
Drug	ionomycin calcium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA	RNF19B F8 ZNF500 TRAPPC10 PCCA MRTFA EPHA3	2.56e-05	198	99	7	871_DN
Drug	Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; MCF7; HT_HG-U133A	ETV5 HIF3A SRGAP3 DGKI AGBL2 INO80B MRTFA	2.56e-05	198	99	7	6496_UP
Drug	L(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; HL60; HT_HG-U133A	ELOA2 RMND5A SIPA1L3 PRR7 AGTR2 TRAPPC9 INO80B	2.65e-05	199	99	7	3118_UP
Drug	Naftopidil dihydrochloride [57149-08-3]; Down 200; 8.6uM; MCF7; HT_HG-U133A	EPM2A ZFYVE16 MAP4 B4GALT1 PTPN9 ALMS1 AKT2	2.65e-05	199	99	7	7331_DN
Drug	haloperidol; Down 200; 10uM; PC3; HT_HG-U133A	EPM2A MAP4 RNF19B ASAP3 C15orf39 ZNF500 TRAPPC9	2.65e-05	199	99	7	1203_DN
Drug	Pargyline hydrochloride [306-07-0]; Up 200; 20.4uM; MCF7; HT_HG-U133A	ASAP3 LAMC3 HIF3A TEX15 B4GALT1 TG NKX2-5	2.73e-05	200	99	7	2265_UP
Drug	mercuric bromide	ADAMTS1 MAP4 ATL3 MCM7 BCL11A GRIN2A HIF3A BCO1 SLIT3 DGKI SEMA6A SIPA1L2 MAP2K6 MEGF10 OPLAH	6.17e-05	1076	99	15	ctd:C042720
Drug	P(1),P(5)-di(adenosine-5'-)pentaphosphate	NUDT11 NUDT10	1.12e-04	4	99	2	ctd:C012275
Drug	3H-MA	GUSB KEL	1.12e-04	4	99	2	CID000194573
Drug	Securinine [5610-40-2]; Down 200; 18.4uM; HL60; HT_HG-U133A	MAP4 DUS4L BCL11A HAL PCCA MRTFA	1.69e-04	187	99	6	2729_DN
Drug	CAS 79350-37-1	GUSB KEL MRTFA	1.71e-04	25	99	3	CID000002675
Drug	Trifluoperazine dihydrochloride [440-17-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A	RMND5A MAP4 RNF19B TECPR2 PCM1 MRTFA	1.74e-04	188	99	6	5442_UP
Drug	Clonidine hydrochloride [4205-91-8]; Down 200; 15uM; MCF7; HT_HG-U133A	POLG RNF19B B4GALT1 MAP2K6 PCM1 INO80B	1.84e-04	190	99	6	3172_DN
Drug	Sanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A	ZFYVE16 POLG ALMS1 AGL PRKDC HERC1	1.89e-04	191	99	6	4168_DN
Drug	Astemizole [68844-77-9]; Down 200; 8.8uM; PC3; HT_HG-U133A	POLG SIPA1L3 ASAP3 NUDT11 LTBP2 MAP2K6	1.89e-04	191	99	6	4471_DN
Drug	BIRB796	NUDT11 NUDT10 MAP2K6 EPHA3	1.97e-04	66	99	4	CID000156422
Drug	thioridazine hydrochloride; Down 200; 10uM; HL60; HT_HG-U133A	MAP4 BCL11A TECPR2 MLPH PCM1 INO80B	2.00e-04	193	99	6	2690_DN
Drug	Norethynodrel [68-23-5]; Down 200; 13.4uM; HL60; HT_HG-U133A	MAP4 POLG BCL11A PRR7 TECPR2 HAL	2.00e-04	193	99	6	1860_DN
Drug	Iopromide [73334-07-3]; Down 200; 5uM; HL60; HT_HG-U133A	ELOA2 RMND5A MAP4 POLG PRR7 MRTFA	2.06e-04	194	99	6	2739_DN
Drug	Artemisinin [63968-64-9]; Up 200; 14.2uM; PC3; HT_HG-U133A	ELOA2 POLG RNF19B BCL11A ZNF500 INO80B	2.06e-04	194	99	6	7247_UP
Drug	Solanine alpha [20562-02-1]; Down 200; 4.6uM; HL60; HT_HG-U133A	MAP4 RNF19B ETV5 C15orf39 ST8SIA5 TRAPPC9	2.12e-04	195	99	6	2152_DN
Drug	Harmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; MCF7; HT_HG-U133A	MAP4 C15orf39 B4GALT1 TECPR2 LTBP2 INO80B	2.12e-04	195	99	6	2805_UP
Drug	Methazolamide [554-57-4]; Up 200; 17uM; MCF7; HT_HG-U133A	ASAP3 ETV5 TEX15 PLG TRAPPC9 MRTFA	2.12e-04	195	99	6	6268_UP
Drug	Bufexamac [2438-72-4]; Down 200; 18uM; HL60; HT_HG-U133A	MAP4 RNF19B HIF3A MAP2K6 TRAPPC9 MRTFA	2.17e-04	196	99	6	2382_DN
Drug	Fillalbin [4540-25-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A	RMND5A ASAP3 SRGAP3 KEL MMP2 MRTFA	2.17e-04	196	99	6	4172_DN
Drug	Ergocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A	MYO3A AKT2 SEMA6A PLG MAP2K6 TRAPPC9	2.17e-04	196	99	6	3817_UP
Drug	Dyclonine hydrochloride [536-43-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A	POLG C15orf39 ALMS1 SSH1 ZNF500 PCM1	2.17e-04	196	99	6	7022_DN
Drug	Fluticasone propionate [80474-14-2]; Down 200; 8uM; MCF7; HT_HG-U133A	MAP4 DUS4L SIPA1L3 C15orf39 MRTFA EPHA3	2.17e-04	196	99	6	7348_DN
Drug	Canrenoic acid potassium salt [2181-04-6]; Down 200; 10uM; PC3; HT_HG-U133A	ZDHHC18 RNF19B ETV5 TRAPPC10 PCCA INO80B	2.17e-04	196	99	6	2065_DN
Drug	Tetracycline hydrochloride [64-75-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A	RMND5A BCL11A SRGAP3 AKT2 LTBP2 MRTFA	2.17e-04	196	99	6	2243_UP
Drug	haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A_EA	MAP4 DUS4L TECPR2 MAP2K6 TRAPPC9 INO80B	2.17e-04	196	99	6	1024_DN
Drug	Carbenoxolone disodium salt [7421-40-1]; Up 200; 6.6uM; PC3; HT_HG-U133A	ELOA2 RMND5A ASAP3 AGTR2 DGKI TRAPPC9	2.17e-04	196	99	6	4093_UP
Drug	Glycocholic acid [475-31-0]; Up 200; 8.6uM; MCF7; HT_HG-U133A	RMND5A MAP4 RNF19B ASAP3 C15orf39 ALMS1	2.17e-04	196	99	6	3315_UP
Drug	Condelphine [7633-69-4]; Down 200; 8.8uM; PC3; HT_HG-U133A	ZDHHC18 MAP4 ASAP3 PTPN9 TECPR2 PCM1	2.17e-04	196	99	6	6357_DN
Drug	Thioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; MCF7; HT_HG-U133A	ELOA2 RMND5A MAP4 AKT2 AGBL2 MRTFA	2.17e-04	196	99	6	2236_UP
Drug	Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; HL60; HT_HG-U133A	SIPA1L3 RNF19B LTBP2 PCCA PCM1 MRTFA	2.17e-04	196	99	6	2372_DN
Drug	Indapamide [26807-65-8]; Up 200; 10.6uM; HL60; HT_HG-U133A	RMND5A SIPA1L3 RNF19B ST8SIA5 SEMA6A MRTFA	2.23e-04	197	99	6	2361_UP
Drug	Chenodiol [474-25-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A	RMND5A MAP4 POLG RNF19B ASAP3 INO80B	2.23e-04	197	99	6	6012_DN
Drug	PNU-0251126 [267429-19-6]; Down 200; 1uM; PC3; HT_HG-U133A	DUS4L ASAP3 TECPR2 PCM1 INO80B MRTFA	2.23e-04	197	99	6	3692_DN
Drug	Flecainide acetate [54143-56-5]; Down 200; 8.4uM; HL60; HT_HG-U133A	ELOA2 ZFYVE16 MAP4 RNF19B PRR7 MRTFA	2.23e-04	197	99	6	2557_DN
Drug	Raloxifene hydrochloride [82640-04-8]; Down 200; 7.8uM; HL60; HT_HG-U133A	ADAMTS1 MAP4 PRR7 PCM1 INO80B MRTFA	2.23e-04	197	99	6	2738_DN
Drug	Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; PC3; HT_HG-U133A	POLG SIPA1L3 ETV5 C15orf39 LTBP2 PCM1	2.23e-04	197	99	6	5044_DN
Drug	Carbarsone [121-59-5]; Down 200; 15.4uM; MCF7; HT_HG-U133A	MAP4 SIPA1L3 RNF19B F8 ALMS1 INO80B	2.23e-04	197	99	6	3250_DN
Drug	Quipazine dimaleate salt [4774-24-7]; Down 200; 9uM; MCF7; HT_HG-U133A	SIPA1L3 KEL MMP2 PCM1 INO80B EPHA3	2.23e-04	197	99	6	2782_DN
Drug	Butoconazole nitrate [32872-77-1]; Down 200; 8.4uM; PC3; HT_HG-U133A	RMND5A ASAP3 ETV5 BCL11A PRR7 PTPN9	2.23e-04	197	99	6	6288_DN
Drug	Chlorphensin carbamate [886-74-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A	POLG C15orf39 PTPN9 AKT2 LTBP2 MAP2K6	2.23e-04	197	99	6	7472_DN
Drug	Gentamicine sulfate [1405-41-0]; Down 200; 2.6uM; PC3; HT_HG-U133A	EPM2A MAP4 ASAP3 ETV5 PCCA INO80B	2.23e-04	197	99	6	2082_DN
Drug	Diethylcarbamazine citrate [1642-54-2]; Down 200; 10.2uM; HL60; HT_HG-U133A	ADAMTS1 MAP4 RNF19B HIF3A PCCA TRAPPC9	2.30e-04	198	99	6	2394_DN
Drug	Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; HL60; HT_HG-U133A	MAP4 SIPA1L3 ETV5 TG TECPR2 PCM1	2.30e-04	198	99	6	2336_UP
Drug	Acenocoumarol [152-72-7]; Up 200; 11.4uM; MCF7; HT_HG-U133A	EPM2A SIPA1L3 RNF19B TG PLG PCM1	2.30e-04	198	99	6	7232_UP
Drug	Dyclonine hydrochloride [536-43-6]; Down 200; 12.2uM; HL60; HT_HG-U133A	MAP4 RNF19B HIF3A ST8SIA5 TRAPPC9 MRTFA	2.30e-04	198	99	6	2392_DN
Drug	Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A	RMND5A MAP4 ASAP3 DGKI INO80B EPHA3	2.30e-04	198	99	6	6503_UP
Drug	Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A	RMND5A MAP4 B4GALT1 AKT2 LTBP2 PCM1	2.30e-04	198	99	6	4729_DN
Drug	Metampicillin sodium salt [6489-61-8]; Down 200; 10.4uM; PC3; HT_HG-U133A	ZFYVE16 ETV5 BCL11A PRR7 ALMS1 PCCA	2.30e-04	198	99	6	2123_DN
Drug	Apramycin [37321-09-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A	MAP4 RNF19B B4GALT1 AKT2 PCM1 INO80B	2.30e-04	198	99	6	7334_DN
Drug	Nifenazone [2139-47-1]; Down 200; 13uM; MCF7; HT_HG-U133A	ZDHHC18 MAP4 RNF19B C15orf39 AKT2 INO80B	2.30e-04	198	99	6	6016_DN
Drug	2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A	ELOA2 MAP4 LAMC3 TECPR2 PCM1 MRTFA	2.30e-04	198	99	6	5211_UP
Drug	estradiol, USP; Down 200; 0.01uM; HL60; HG-U133A	POLG RNF19B ASAP3 ETV5 AGTR2 ZNF500	2.30e-04	198	99	6	387_DN
Drug	Cinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A	ZDHHC18 EPM2A MAP4 POLG MAP2K6 PCM1	2.30e-04	198	99	6	7174_DN
Drug	U-62066 [87151-85-7]; Down 200; 1uM; MCF7; HT_HG-U133A	ASAP3 ETV5 ALMS1 MMP2 PCM1 MRTFA	2.30e-04	198	99	6	3901_DN
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A	ELOA2 SIPA1L3 RNF19B SEMA6A PCM1 MRTFA	2.30e-04	198	99	6	6930_UP
Drug	Ungerine nitrate; Up 200; 10.2uM; HL60; HT_HG-U133A	ASAP3 LAMC3 GRIN2A TEX15 LTBP2 INO80B	2.36e-04	199	99	6	2514_UP
Drug	Medrysone [2668-66-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A	ASAP3 BCL11A HIF3A TEX15 TRAPPC9 MRTFA	2.36e-04	199	99	6	3603_UP
Drug	Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; PC3; HT_HG-U133A	SIPA1L3 ASAP3 ETV5 B4GALT1 TG TRAPPC10	2.36e-04	199	99	6	7367_UP
Drug	Sulfamethizole [144-82-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A	MAP4 POLG RNF19B ALMS1 MMP2 MRTFA	2.36e-04	199	99	6	6272_UP
Drug	Niflumic acid [4394-00-7]; Down 200; 14.2uM; HL60; HT_HG-U133A	ADAMTS1 MAP4 SIPA1L3 RNF19B LTBP2 PCCA	2.36e-04	199	99	6	2399_DN
Drug	Lycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A	RNF19B BCO1 ALMS1 LTBP2 MMP2 PCM1	2.36e-04	199	99	6	3891_DN
Drug	Probenecid [57-66-9]; Up 200; 14uM; HL60; HT_HG-U133A	MAP4 ASAP3 MYO3A AKT2 INO80B MRTFA	2.36e-04	199	99	6	2464_UP
Drug	Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; HL60; HT_HG-U133A	ZFYVE16 ADAMTS1 SIPA1L3 TECPR2 TRAPPC9 INO80B	2.36e-04	199	99	6	2343_UP
Drug	Midodrine hydrochloride [3092-17-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A	MAP4 RNF19B B4GALT1 MAP2K6 PCM1 INO80B	2.36e-04	199	99	6	6804_DN
Drug	Idazoxan hydrochloride [79944-56-2]; Down 200; 16.6uM; MCF7; HT_HG-U133A	EPM2A MAP4 SIPA1L3 SSH1 TRAPPC10 INO80B	2.36e-04	199	99	6	5347_DN
Drug	Cefotaxime sodium salt [64485-93-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A	ASAP3 TG KEL LTBP2 AGBL2 MRTFA	2.36e-04	199	99	6	2235_UP
Drug	Cotinine (-) [486-56-6]; Up 200; 22.6uM; HL60; HG-U133A	ADAMTS1 POLG ETV5 ST8SIA5 MAP2K6 INO80B	2.42e-04	200	99	6	2011_UP
Drug	Decamethonium bromide [541-22-0]; Up 200; 9.6uM; PC3; HT_HG-U133A	ELOA2 RMND5A B4GALT1 AGTR2 INO80B MRTFA	2.42e-04	200	99	6	4094_UP
Drug	Chlorhexidine [55-56-1]; Down 200; 8uM; MCF7; HT_HG-U133A	ELOA2 RMND5A SIPA1L3 RNF19B MAP2K6 TRAPPC9	2.42e-04	200	99	6	5403_DN
Drug	Noscapine [128-62-1]; Up 200; 9.6uM; MCF7; HT_HG-U133A	ELOA2 ASAP3 GRIN2A TECPR2 PLG PCM1	2.42e-04	200	99	6	7204_UP
Drug	Tropicamide [1508-75-4]; Up 200; 14uM; MCF7; HT_HG-U133A	ASAP3 TEX15 NUDT11 SEMA6A MMP2 MRTFA	2.42e-04	200	99	6	3619_UP
Drug	neocarzinostatin chromophore	POLG LARS1 F8 B4GALT1 NUDT10 LTBP2 OTOG	2.66e-04	288	99	7	CID000447545
Drug	3',5'-diiodothyronine	TG GUSB	2.78e-04	6	99	2	CID000093328
Drug	4-aminophenylmercuriacetate	MMP2 PLG	2.78e-04	6	99	2	ctd:C010024
Drug	3-hydroxy-4-pyridone	TG GUSB	2.78e-04	6	99	2	CID000105085
Disease	Esophageal Dysphagia	TSEN54 MEGF10	6.26e-05	4	96	2	C0267072
Disease	Oropharyngeal Dysphagia	TSEN54 MEGF10	6.26e-05	4	96	2	C0267071
Disease	Deglutition Disorders	TSEN54 MEGF10	6.26e-05	4	96	2	C0011168
Disease	hypoglycemia (is_implicated_in)	AGTR2 AKT2	2.90e-04	8	96	2	DOID:9993 (is_implicated_in)
Disease	creatinine measurement	ZDHHC18 SIPA1L3 ETV5 KBTBD2 B4GALT1 PTPN9 ALMS1 AKT2 MEGF10 MRTFA OPLAH	3.92e-04	995	96	11	EFO_0004518
Disease	Semantic-Pragmatic Disorder	BCL11A GRIN2A	5.65e-04	11	96	2	C0454655
Disease	Auditory Processing Disorder, Central	BCL11A GRIN2A	5.65e-04	11	96	2	C0751257
Disease	hyperhomocysteinemia (implicated_via_orthology)	GRIN2A F8	5.65e-04	11	96	2	DOID:9279 (implicated_via_orthology)
Disease	Language Delay	BCL11A GRIN2A	5.65e-04	11	96	2	C0023012
Disease	Language Development Disorders	BCL11A GRIN2A	5.65e-04	11	96	2	C0023014
Disease	Marfan Syndrome	LTBP2 MMP2	5.65e-04	11	96	2	C0024796
Disease	Speech Delay	BCL11A GRIN2A	5.65e-04	11	96	2	C0241210
Disease	Cardiomyopathy, Familial Idiopathic	ALMS1 NKX2-5 PCCA	5.85e-04	50	96	3	C1449563
Disease	creatinine measurement, glomerular filtration rate	SIPA1L3 ETV5 KBTBD2 ALMS1	5.89e-04	117	96	4	EFO_0004518, EFO_0005208
Disease	congenital diaphragmatic hernia (implicated_via_orthology)	SLIT3 AGTR2	6.77e-04	12	96	2	DOID:3827 (implicated_via_orthology)
Disease	focal segmental glomerulosclerosis (biomarker_via_orthology)	AGTR2 MMP2	6.77e-04	12	96	2	DOID:1312 (biomarker_via_orthology)
Disease	ovarian carcinoma (is_implicated_in)	AKT2 MAP2K6	1.07e-03	15	96	2	DOID:4001 (is_implicated_in)
Disease	methadone dose measurement	EPM2A BCL11A TEX15	1.10e-03	62	96	3	EFO_0007907
Disease	gut microbiome measurement, taxonomic microbiome measurement	ABCA13 SIPA1L3 ETV5	1.32e-03	66	96	3	EFO_0007874, EFO_0007883
Disease	atrial fibrillation	SLIT3 NKX2-5 HERC1 PCCA PCM1 EPHA3	1.36e-03	371	96	6	EFO_0000275
Disease	bipolar disorder, sex interaction measurement	SLIT3 SIPA1L2	1.55e-03	18	96	2	EFO_0008343, MONDO_0004985
Disease	Paroxysmal atrial fibrillation	SLIT3 NKX2-5 HERC1 EPHA3	1.71e-03	156	96	4	C0235480
Disease	familial atrial fibrillation	SLIT3 NKX2-5 HERC1 EPHA3	1.71e-03	156	96	4	C3468561
Disease	Persistent atrial fibrillation	SLIT3 NKX2-5 HERC1 EPHA3	1.71e-03	156	96	4	C2585653
Disease	Atrial Fibrillation	SLIT3 NKX2-5 HERC1 EPHA3	1.88e-03	160	96	4	C0004238
Disease	Deep Vein Thrombosis	F8 PLG	2.11e-03	21	96	2	C0149871
Disease	Venous Thrombosis	F8 PLG	2.11e-03	21	96	2	C0042487
Disease	Nasopharyngeal carcinoma	AKT2 MMP2	2.32e-03	22	96	2	C2931822
Disease	high density lipoprotein particle size measurement	DXO ZDHHC18 PLG AGBL2	2.34e-03	170	96	4	EFO_0008592
Disease	Schizophrenia	ABCA13 ACP1 BCL11A GRIN2A SRGAP3 SLIT3 PLG MEGF10 PCM1	2.35e-03	883	96	9	C0036341

Protein segments in the cluster

Peptide	Gene	Start	Entry
KQRAPGEDPMDYKCG	AKT2	111	P31751
VKMGGRYAPRDCVSP	B4GALT1	161	P15291
RPDMKTELFSSSCPG	APOM	116	O95445
PKPSAESDMGTRRDY	ASAP3	516	Q8TDY4
GVNACIMAFPPEKYA	AGTR2	191	P50052
YQAAKSVMRSEPEGC	ALMS1	2381	Q8TCU4
DEPSSGMDPCSKRYL	ABCA13	4881	Q86UQ4
TMRKPRCGNPDVANY	MMP2	96	P08253
MKCKPNQTRTYDPEG	NUDT10	1	Q8NFP7
ENCYQHMGTSKSPAP	RIMBP3B	1311	A6NNM3
ENCYQHMGTSKSPAP	RIMBP3C	1311	A6NJZ7
YTMRECDNPVPKNGG	ADAMTS1	581	Q9UHI8
CSMSPGNLEKNRYGD	PTPN9	321	P43378
PMPTAVLEKYCEASG	KIAA0895L	171	Q68EN5
PKSSECGYVEMKSPA	MEGF10	1041	Q96KG7
CGYVEMKSPARRDSP	MEGF10	1046	Q96KG7
DGKEDPCIPQRDMFY	OVOS1	571	Q6IE37
KMPVYSGSRPACQLQ	ELOA2	511	Q8IYF1
NSSGCNRYPEPMTPD	EPM2A	201	O95278
SGKRPDYAPMESSDE	MFAP1	41	P55081
PLKDSYGMSPCNTAV	MAP4	171	P27816
DASAMVYPPREVCGA	LRSAM1	181	Q6UWE0
PCVMFYSSNPGEKVK	HERC1	2171	Q15751
PGMSAEYAPQGICKD	BCL11A	151	Q9H165
NMPPSLDCRYNREGE	PCM1	596	Q15154
DCKTPSNPTGMERRY	POLG	1196	P54098
MAANIPAKRYSDPCV	KBTBD2	511	Q8IY47
KENGPMASDPLCLTY	F8	161	P00451
FQSPMGIKQEPRDYC	ETV5	286	P41161
MKCKPNQTRTYDPEG	NUDT11	1	Q96G61
MPANYTCTRPDGDNT	GPR174	1	Q9BXC1
KEDPCIPQRDMFYNG	OVOS2	621	Q6IE36
CVGPAPTSKSYLNMD	PCCA	111	P05165
CMLAAFKPEAYAGPE	NKX2-5	46	P52952
FEQYMCADKPGSSPD	DXO	191	O77932
CREKQPMVPESLADY	MCM7	566	P33993
GQDCKYTPMFGPEAR	SMPD4	576	Q9NXE4
AAAPAPMVRYCSGAQ	INO80B	266	Q9C086
RQAESDMSKPPCYEE	PRR7	141	Q8TB68
VGYSCMPSNKDEDGL	NUP54	176	Q7Z3B4
YVCVARNPSGDDTKM	IGSF10	2211	Q6WRI0
MFNASCLPYVPEKGT	HAL	236	P42357
DSDPGDPCKMRNSSY	GFRAL	51	Q6UXV0
TYKSIPMQVDGEPCR	DGKI	671	O75912
NSEESGNFPMRKVPC	GAS2L3	96	Q86XJ1
NNSYMFKREPPEGCE	FAM117B	461	Q6P1L5
GMLYPQESPSRECKE	GUSB	26	P08236
PATKRGCAAMAAYPS	AGBL2	881	Q5U5Z8
VNNSKEEDPPRMYCS	EPHA3	231	P29320
NMEEVCGGEKPYLSP	ATL3	366	Q6DD88
PAPTRMDCYSGQKGH	LTBP2	1406	Q14767
VKEGMDDFRYGCPSP	FAM47A	51	Q5JRC9
NPAMFAGYEETPLKC	DUS4L	246	O95620
NMSLPHPCQTESGYK	ATRIP	256	Q8WXE1
AMRDYCPSQQKASPA	GPRIN1	41	Q7Z2K8
CTGPEARQEVPMYTD	FAM120B	416	Q96EK7
NADPSSEAKAMAVPY	MLPH	531	Q9BV36
PRCQMVYNAGPERDS	OTOG	136	Q6ZRI0
TIDAGCKPYMAPERI	MAP2K6	211	P52564
YCPMEQSPGDAKQIF	RMND5A	376	Q9H871
PCPRCSAYIIKMNDG	RNF19B	286	Q6ZMZ0
PGKPYARMCISGFDE	TSEN54	466	Q7Z6J9
SFTPKEMGRCLASYP	SAXO1	411	Q8IYX7
RYTIYSPKDGQPCMD	LARS1	236	Q9P2J5
PPRVDKMTQCYFEGG	OPLAH	656	O14841
CSGHMRAYKPPAQTS	HIF3A	191	Q9Y2N7
EIGNPPDYRGQSCMK	ACP1	51	P24666
PGYFDARNPDMNKCI	RSPO1	81	Q2MKA7
PMVEYKLDSEGTPCE	SIPA1L2	1041	Q9P2F8
VCYSMAVTRSKDAPP	SIPA1L3	761	O60292
CNLPPISEKYTMDVG	ST8SIA5	191	O15466
MVRYSLDPENPTKSC	RPL17	1	P18621
LTMNYCRNPDADKGP	PLG	421	P00747
SLSMERGCPPQRDSY	RBMXL2	351	O75526
QKQDRGAPPMDSSYA	MRTFA	246	Q969V6
VGKPSPYMFECITEN	PDXP	211	Q96GD0
DCMYPTASGAPEASR	SSH1	651	Q8WYL5
SEFGTMAYPDPCKNI	BCO1	91	Q9HAY6
SYFSCPMAGTPKAES	C15orf39	46	Q6ZRI6
CLFYRSPAEGPEKMQ	C15orf39	91	Q6ZRI6
EAMESSGKRAPQCYP	CNOT10	621	Q9H9A5
YKEPGIARCSSPEPM	SLIT3	876	O75094
MKVPRENHCSPGSSY	ZC3H6	561	P61129
YNKNLGMVCRKPTDP	WASHC5	1056	Q12768
SPRELEGPVYEKCMA	SRGAP3	696	O43295
CPYCPMEQNPADGKR	RMND5B	376	Q96G75
NPSCRNYKMDTLEPF	SEMA6A	141	Q9H2E6
VIVPKQSAGPDYCDM	STAMBPL1	311	Q96FJ0
PPEAEMRAYAACQDA	TECPR2	1166	O15040
TADGEPSAKYMCPEK	TSHZ3	36	Q63HK5
EYCQMLGRPKSFIPS	SEC16B	611	Q96JE7
PGTPRFNNYVDCMKK	PRKDC	1731	P78527
LSYACPKNMLGEREP	ZCRB1	116	Q8TBF4
SLENYTSKCPGTMEP	TRAPPC9	506	Q96Q05
GSEDYDCIPPNKVTM	TEX15	131	Q9BXT5
VKAEIFPPSGMEYCR	TRAPPC10	1061	P48553
PPGKMCSADYADLLQ	TG	1301	P01266
MKDCEYQQISPGAAP	ZDHHC18	1	Q9NUE0
SDEIQPLYMGRCSKP	ZFYVE16	111	Q7Z3T8
VYLSGEEPRCMDPAQ	ZNF500	231	O60304
KCPVSRMYPTDDSAP	AGL	1176	P35573
SYAQVMCRKPSPQDS	KEL	676	P23276
YGSALAPRPADKCMP	LAMC3	851	Q9Y6N6
YKSSEEPRMSPDTCA	MYO3A	1006	Q8NEV4
AKASCYGQMERPEVP	GRIN2A	316	Q12879