Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpotassium:chloride symporter activity

SLC12A4 SLC12A6

3.42e-059202GO:0015379
GeneOntologyMolecularFunctionammonium channel activity

SLC12A4 SLC12A6

6.25e-0512202GO:0008519
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC12A4 SLC12A6

2.38e-0423202GO:0015377
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC12A4 SLC12A6

3.05e-0426202GO:0015296
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC12A4 SLC12A6 KCNQ4

5.90e-04167203GO:0015079
GeneOntologyBiologicalProcessammonium import across plasma membrane

SLC12A4 SLC12A6

5.35e-064202GO:0140157
GeneOntologyBiologicalProcessammonium transmembrane transport

SLC12A4 SLC12A6

6.92e-0513202GO:0072488
GeneOntologyBiologicalProcesschloride ion homeostasis

SLC12A4 SLC12A6

2.64e-0425202GO:0055064
GeneOntologyBiologicalProcessmonoatomic anion homeostasis

SLC12A4 SLC12A6

3.33e-0428202GO:0055081
GeneOntologyBiologicalProcesspotassium ion homeostasis

SLC12A4 SLC12A6

5.83e-0437202GO:0055075
GeneOntologyBiologicalProcesscell volume homeostasis

SLC12A4 SLC12A6

7.51e-0442202GO:0006884
DomainKCC1

SLC12A4 SLC12A6

1.09e-062202IPR000622
DomainTyr_Pase_non-rcpt_typ-14/21

PTPN14 PTPN21

1.09e-062202IPR014392
DomainKCL_cotranspt

SLC12A4 SLC12A6

6.53e-064202IPR000076
DomainSLC12A_fam

SLC12A4 SLC12A6

2.28e-057202IPR004842
DomainSLC12_C

SLC12A4 SLC12A6

3.04e-058202IPR018491
DomainSLC12

SLC12A4 SLC12A6

3.04e-058202PF03522
DomainAA-permease/SLC12A_dom

SLC12A4 SLC12A6

2.48e-0422202IPR004841
DomainAA_permease

SLC12A4 SLC12A6

2.48e-0422202PF00324
DomainFERM_CS

PTPN14 PTPN21

2.96e-0424202IPR019747
DomainFERM_C

PTPN14 PTPN21

3.49e-0426202PF09380
DomainFERM_C

PTPN14 PTPN21

3.76e-0427202SM01196
DomainFERM_PH-like_C

PTPN14 PTPN21

3.76e-0427202IPR018980
DomainFERM_N

PTPN14 PTPN21

5.64e-0433202IPR018979
DomainFERM_N

PTPN14 PTPN21

5.64e-0433202PF09379
DomainPTPc

PTPN14 PTPN21

6.72e-0436202SM00194
DomainBROMODOMAIN_1

BAZ2B BRD8

7.09e-0437202PS00633
DomainBromodomain

BAZ2B BRD8

7.48e-0438202PF00439
DomainTYR_PHOSPHATASE_PTP

PTPN14 PTPN21

7.88e-0439202PS50055
DomainPTPase_domain

PTPN14 PTPN21

8.71e-0441202IPR000242
DomainBROMODOMAIN_2

BAZ2B BRD8

8.71e-0441202PS50014
DomainY_phosphatase

PTPN14 PTPN21

8.71e-0441202PF00102
DomainBROMO

BAZ2B BRD8

9.14e-0442202SM00297
DomainBromodomain

BAZ2B BRD8

9.14e-0442202IPR001487
Domain-

BAZ2B BRD8

9.14e-04422021.20.920.10
DomainFERM_M

PTPN14 PTPN21

1.10e-0346202PF00373
DomainFERM_domain

PTPN14 PTPN21

1.24e-0349202IPR000299
DomainFERM_central

PTPN14 PTPN21

1.24e-0349202IPR019748
Domain-

PTPN14 PTPN21

1.24e-03492021.20.80.10
DomainFERM_1

PTPN14 PTPN21

1.29e-0350202PS00660
DomainFERM_2

PTPN14 PTPN21

1.29e-0350202PS00661
DomainB41

PTPN14 PTPN21

1.29e-0350202SM00295
DomainFERM/acyl-CoA-bd_prot_3-hlx

PTPN14 PTPN21

1.29e-0350202IPR014352
DomainFERM_3

PTPN14 PTPN21

1.29e-0350202PS50057
DomainBand_41_domain

PTPN14 PTPN21

1.29e-0350202IPR019749
DomainTyr_Pase_cat

PTPN14 PTPN21

1.80e-0359202IPR003595
DomainPTPc_motif

PTPN14 PTPN21

1.80e-0359202SM00404
DomainTyr_Pase_AS

PTPN14 PTPN21

2.74e-0373202IPR016130
DomainTYR_PHOSPHATASE_1

PTPN14 PTPN21

3.77e-0386202PS00383
DomainTYR_PHOSPHATASE_2

PTPN14 PTPN21

3.86e-0387202PS50056
DomainTYR_PHOSPHATASE_dom

PTPN14 PTPN21

3.86e-0387202IPR000387
Domain-

PTPN14 PTPN21

4.30e-03922023.90.190.10
DomainProt-tyrosine_phosphatase-like

PTPN14 PTPN21

4.97e-0399202IPR029021
DomainUbiquitin-rel_dom

PTPN14 PTPN21

1.63e-02184202IPR029071
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A4 SLC12A6

2.53e-057162M27339
PathwayREACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS

SLC12A4 SLC12A6

2.53e-057162MM15081
Pubmed

Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD mice.

SLC12A4 SLC12A6

3.14e-07220217510708
Pubmed

Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.

SLC12A4 SLC12A6

3.14e-07220234031912
Pubmed

Genetic disruption of KCC cotransporters in a mouse model of thalassemia intermedia.

SLC12A4 SLC12A6

3.14e-07220231835175
Pubmed

Combined genetic disruption of K-Cl cotransporters and Gardos channel KCNN4 rescues erythrocyte dehydration in the SAD mouse model of sickle cell disease.

SLC12A4 SLC12A6

9.42e-07320231352162
Pubmed

A dominant negative mutant of the KCC1 K-Cl cotransporter: both N- and C-terminal cytoplasmic domains are required for K-Cl cotransport activity.

SLC12A4 SLC12A6

9.42e-07320211551954
Pubmed

Erythroid-specific inactivation of Slc12a6/Kcc3 by EpoR promoter-driven Cre expression reduces K-Cl cotransport activity in mouse erythrocytes.

SLC12A4 SLC12A6

9.42e-07320235274823
Pubmed

K-Cl cotransporter gene expression during human and murine erythroid differentiation.

SLC12A4 SLC12A6

9.42e-07320221733850
Pubmed

Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells.

SLC12A4 SLC12A6

9.42e-07320215262997
Pubmed

Influence of K-Cl cotransporter activity on activation of volume-sensitive Cl- channels in human osteoblasts.

SLC12A4 SLC12A6

1.88e-06420212637262
Pubmed

Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition.

SLC12A4 SLC12A6

8.78e-06820211395011
Pubmed

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters.

SLC12A4 SLC12A6

8.78e-06820224393035
Pubmed

Similar effects of all WNK3 variants on SLC12 cotransporters.

SLC12A4 SLC12A6

8.78e-06820221613606
Pubmed

Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1).

SLC12A4 SLC12A6

8.78e-06820212386165
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

DNAH9 BAZ2B BRD8

1.07e-057520325593309
Pubmed

Cation-chloride cotransporters and neuronal function.

SLC12A4 SLC12A6

1.13e-05920219323993
Pubmed

Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.

SLC12A4 SLC12A6

2.07e-051220227782176
Pubmed

Rare independent mutations in renal salt handling genes contribute to blood pressure variation.

SLC12A4 SLC12A6

7.21e-052220218391953
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DEPDC1B CEP95 RABEP1 PTPN14 PTPN21

1.05e-0486120536931259
Pubmed

Protein Binder Toolbox for Studies of Solute Carrier Transporters.

SLC12A4 SLC12A6

4.75e-045620238878854
InteractionOR10S1 interactions

SLC12A4 SLC12A6

2.61e-058202int:OR10S1
InteractionOR2G6 interactions

SLC12A4 SLC12A6

1.42e-0418202int:OR2G6
InteractionCNFN interactions

SLC12A4 EVX2

1.42e-0418202int:CNFN
InteractionRGS9BP interactions

SLC12A6 RABEP1

1.42e-0418202int:RGS9BP
CytobandEnsembl 112 genes in cytogenetic band chr1q41

SPATA17 PTPN14

7.53e-0493202chr1q41
GeneFamilyProtein tyrosine phosphatases, non-receptor type

PTPN14 PTPN21

6.14e-0518122812
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

PTPN14 PTPN21

4.86e-04501221293
GeneFamilySolute carriers

SLC12A4 SLC12A6

2.72e-02395122752
CoexpressionGSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN

CEP95 CHST11 PTPN14 PTPN21

1.45e-05200204M6193
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRF4 SPATA17 PTPN14

6.94e-051812036956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Striatum / BrainAtlas - Mouse McCarroll V32

ADGRF4 EVX2

8.18e-049520256350551af6a1ae15652d596002124d8f7885d4f
ToppCell(09)_Ionocytes-(3)_72hpi|(09)_Ionocytes / shred by cell type and Timepoint

RABEP1 FAM20C

1.09e-03110202fce7d5a0617fc664b657f5bb9abb290e7cc234cb
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP95 PTPN14

1.28e-03119202c3f1223356e7f245a460ea5568a223e34e458dc1
ToppCellpdx-Tumor_cells-T9|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CEP95 PTPN14

1.86e-031442020b94d978262a826c9254145aa98c6c30240243f9
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_ALM_Tgfb1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADGRF4 CHST11

1.89e-0314520284d50a13b48d50c16e768422908e371a55972d0e
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 SPATA17

1.96e-03148202d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 SPATA17

1.96e-03148202c8e93b87212f55774223caa385859c566fa1981f
ToppCellCiliated_cells-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH9 SPATA17

1.99e-031492026399c5a2f06d79f020dece252526f1c0c110d569
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

DNAH9 SPATA17

2.04e-031512028216462e723fec2797387929dde095370947e10a
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND01-03-samps / Age Group, Lineage, Cell class and subclass

DNAH9 SPATA17

2.10e-031532022482247d9c39c7b99bb45fb9153442f64fd6012f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC12A4 DNAH9

2.10e-031532024eb9c2d7e4b95d44198fc87dc115a08ef0153e26
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC12A4 DNAH9

2.10e-0315320226b5b45c117d155b028d298a0b93e16d343dca97
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar|PND01-03-samps / Age Group, Lineage, Cell class and subclass

DNAH9 SPATA17

2.10e-03153202fc0d2d50aa3b6b2772bbf3626c9df5c5e8d7d11e
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC12A4 DNAH9

2.10e-031532020f12e38f2cbf69a520764289b0aa4dedc645f714
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 SPATA17

2.12e-031542024e3bc24043144143842627cacf6f90dda2228910
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 SPATA17

2.12e-031542027556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 SPATA17

2.15e-031552025f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 SPATA17

2.15e-031552020944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DEPDC1B CHST11

2.18e-03156202b28bbdb515317368f1231b0b15d7442352f3b400
ToppCellBAL-Mild-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KCNQ4 URB2

2.18e-031562025d9e1df70f2e9219f6b029be2e39297605d36726
ToppCellCiliated_cells-A-HP_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH9 SPATA17

2.26e-031592020c65ae6140abd48c79b04758a6217709ddd15385
ToppCellCOVID-mono3-|COVID / Condition, Cell_class and T cell subcluster

FAM20C PTPN14

2.37e-0316320226661c7a3a0a449ed32d4b3b28fc2fc0b237025d
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-3|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

DEPDC1B ADGRF4

2.37e-031632020e8d3c98209fc98b86b841d69051cee9e276d837
ToppCellCOVID-mono3|COVID / Condition, Cell_class and T cell subcluster

FAM20C PTPN14

2.37e-031632026ab4cbcd411b40920b81162c0f4b03ea67408f52
ToppCellLPS-IL1RA-Unknown-Endothelial-Monocytes-Macrophages|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC12A4 URB2

2.37e-031632026b11a3ada8725670d0489f404c8c2175ad3904e9
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DEPDC1B CHST11

2.40e-031642021a9b444d2c6abcc83d4355ec5228b27541df2bd0
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 ADGRF4

2.40e-03164202e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCellInfluenza_Severe-cDC|World / Disease group and Cell class

KCNQ4 DEPDC1B

2.40e-03164202c984228f73b9aa1aaf948541f64f41ed874770cd
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNQ4 CHST11

2.46e-031662023b67064a5149e72f895344d938c64b8ff65247f5
ToppCellInfluenza_Severe-cDC|Influenza_Severe / Disease group and Cell class

KCNQ4 DEPDC1B

2.46e-03166202b40bdf0f7f381e25be61188e9f6c294d25a8b824
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

DNAH9 SPATA17

2.49e-0316720226cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell15-Distal-Epithelial-Multiciliated_cell|Distal / Age, Tissue, Lineage and Cell class

DNAH9 SPATA17

2.55e-03169202425d89ab69e9f9eb3df84056676423e390cc6ab1
ToppCellNS-critical-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLC12A4 ADGRF4

2.55e-03169202aec97583b23112060437b619cb429dc32f29285f
ToppCellfacs-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC12A6 UGT1A5

2.61e-0317120243d8fd9b9546e84a652564fe96b514b34b06262b
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

DNAH9 SPATA17

2.61e-0317120274be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 FAM20C

2.61e-03171202f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCellfacs-Lung-nan-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC12A6 UGT1A5

2.61e-03171202a31c23406cf6d6a17358a8fb41d392a7fb0306e0
ToppCell10x5'-Lung-Myeloid_Dendritic-Cycling_Dendritic|Lung / Manually curated celltypes from each tissue

DEPDC1B URB2

2.67e-0317320262e0c18cfed9645e34a9d7029c94a8554f773714
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

FAM20C PTPN21

2.67e-0317320242c911ed16fabdabef063830e8407192d8bde950
ToppCelldroplet-Fat-Gat-18m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH9 SPATA17

2.67e-03173202a40a52d8041d45dc3bef74fe55945ae07aa018d6
ToppCellAdult-Mesenchymal-pericyte_cell-D175|Adult / Lineage, Cell type, age group and donor

KCNQ4 DEPDC1B

2.67e-03173202fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCelldroplet-Fat-Gat-18m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH9 SPATA17

2.67e-03173202f0b4dd1cf41d6ee6abb0e1968b8b39f4fabebcb5
ToppCelldroplet-Fat-Gat-18m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH9 SPATA17

2.67e-03173202f3f67531f72d6d52e19c7f1f2db1ab4026fb70da
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

PTPN14 PTPN21

2.70e-03174202548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

DNAH9 SPATA17

2.70e-03174202f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

DNAH9 SPATA17

2.73e-03175202c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN14 PTPN21

2.73e-0317520231f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH9 KCNQ4

2.73e-03175202887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

SLC12A6 ADGRF4

2.73e-031752020cc215109d9915af47e4d0a120ce2e46910715fa
ToppCellfacs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH9 SPATA17

2.76e-03176202ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH9 KCNQ4

2.76e-03176202c6484334187f64cd00cd35e77d8ae436556b4260
ToppCellCiliated_cells-A-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

DNAH9 SPATA17

2.76e-031762021c364155f46b9a7c995bdc2cc2333c437cd90f5b
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH9 SPATA17

2.79e-03177202e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCellwk_15-18-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CHST11 PTPN14

2.79e-03177202b01d7a6a78169962123ddfb0bb588f51d138ad02
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH9 SPATA17

2.82e-03178202de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellCiliated_cells-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH9 SPATA17

2.82e-03178202255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH9 SPATA17

2.82e-03178202579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH9 SPATA17

2.82e-03178202b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH9 FAM20C

2.82e-0317820230ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

FOLH1B CHST11

2.85e-03179202cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPN14 PTPN21

2.85e-031792024f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHST11 PTPN14

2.85e-03179202ec1d7017da325647b629de703135a404bbdc627d
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAH9 SPATA17

2.85e-03179202d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAH9 SPATA17

2.85e-031792028a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CEP95 PTPN14

2.88e-03180202baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCellAT1_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

PTPN14 PTPN21

2.88e-031802022d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CEP95 PTPN14

2.88e-031802020f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DEPDC1B CHST11

2.88e-03180202b35a8c6169f4b548b912af005e92ae7c6596f376
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CEP95 PTPN14

2.88e-031802022d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH9 SPATA17

2.92e-03181202dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-4|TCGA-Endometrium / Sample_Type by Project: Shred V9

DNAH9 SPATA17

2.92e-0318120251d91b923920463245e95d65c6a5197e21d34d73
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

DNAH9 SPATA17

2.95e-031822027ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|World / disease group, cell group and cell class (v2)

DEPDC1B SPATA17

2.95e-031822029adf90bb2808f234d53b89ca0ae07380478204ad
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

DNAH9 SPATA17

2.95e-03182202fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Deuterosomal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DNAH9 SPATA17

2.95e-03182202000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCellsevere-Myeloid-Neutrophils_1|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SLC12A6 CHST11

2.98e-0318320260a6112aa4fc4f5debda4c7e81b37539ba2e4e6e
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|367C / Donor, Lineage, Cell class and subclass (all cells)

DNAH9 SPATA17

2.98e-03183202b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|367C / Donor, Lineage, Cell class and subclass (all cells)

DNAH9 SPATA17

2.98e-03183202cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 FAM20C

2.98e-03183202facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 FAM20C

2.98e-0318320284b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FAM20C CHST11

2.98e-031832024cc0961a67de76b8d756cd9ffcaa98e3fe3c3a69
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

DEPDC1B SPATA17

2.98e-03183202df8568751205313d149939ea2683097e3652a60b
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PTPN14 PTPN21

3.01e-03184202d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH9 SPATA17

3.01e-031842025daff849625f2f41d56615569c0ed59cd733b34c
ToppCellmild-Myeloid-Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SLC12A6 CHST11

3.01e-031842021a0e8b20b3ac8416d05c2d5934ab4ac80be4cce5
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PTPN14 PTPN21

3.01e-0318420257c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH9 SPATA17

3.04e-031852023e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPN14 PTPN21

3.04e-031852021c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

DNAH9 SPATA17

3.04e-0318520218a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

DNAH9 SPATA17

3.04e-0318520230f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH9 SPATA17

3.04e-031852025e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellCiliated_cells-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

DNAH9 SPATA17

3.04e-031852024fc7113d3dadc716ec5a8e62b58543cc00ce5b16
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH9 SPATA17

3.04e-03185202f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

PTPN14 PTPN21

3.04e-0318520232b4e68e551d435a732f253f6ad83408c759a642
ToppCellP28-Epithelial-airway_epithelial_cell-club_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DNAH9 SPATA17

3.08e-03186202a26811481668fa25c48a064a56c198685693ad8d
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

SLC12A6 CEP95

3.08e-03186202403ac98f72a42721f84fbd7826f251a88ae534a2
ToppCell390C-Epithelial_cells-Epithelial-F_(Ciliated)|390C / Donor, Lineage, Cell class and subclass (all cells)

DNAH9 SPATA17

3.08e-03186202708c5edefe36c91df27cf53c1b5101fb2030cc5a
ToppCellP28-Epithelial-airway_epithelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DNAH9 SPATA17

3.08e-03186202df80f101954b8ec6ccdb03e702de22e70b65181f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPATA17 PTPN14

3.08e-031862025c4ffe4e4d5536ae9f8794277fe032c693e7dd56
DrugPotassium Chloride

SLC12A4 SLC12A6

1.10e-056202DB00761
DrugRubidium

SLC12A6 KCNQ4

2.05e-058202ctd:D012413
DrugChlorogenic acid [327-97-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A

RABEP1 CHST11 PTPN14 PTPN21

2.41e-051982043282_DN
DrugAC1L1ICP

SLC12A4 SLC12A6

3.28e-0510202CID000004520
DrugDCPIB

SLC12A4 SLC12A6

4.01e-0511202CID010071166
DrugBumetanide

SLC12A4 SLC12A6

8.73e-0516202ctd:D002034
DiseaseTinnitus, wellbeing measurement

DNAH9 PTPN21

1.92e-0396202EFO_0007869, HP_0000360
Diseaseepilepsy (implicated_via_orthology)

SLC12A4 SLC12A6

5.40e-03163202DOID:1826 (implicated_via_orthology)
Diseasephosphatidylethanolamine measurement

DEPDC1B RNF111

6.06e-03173202EFO_0010228
Diseaseurate measurement, bone density

DNAH9 BAZ2B SPATA17

8.03e-03619203EFO_0003923, EFO_0004531

Protein segments in the cluster

PeptideGeneStartEntry
RRTQCMMERMMRELV

URB2

566

Q14146
MMERMMRELVQPLLA

URB2

571

Q14146
RIRTMAQFLRDLMLM

BRD8

1161

Q9H0E9
ERRRQHMMLMKAMEA

BAZ2B

1006

Q9UIF8
MMERIRKEMILMERG

EVX2

1

Q03828
GILVIFRRMMKSRMM

ADGRF4

501

Q8IZF3
PENRRKLQLLMRMMA

DEPDC1B

321

Q8WUY9
QRLLMRDMQRMEIVL

RABEP1

291

Q15276
MRFLQILRMVRMDRR

KCNQ4

206

P56696
ILLRMMNDQLMFLER

FOLH1B

351

Q9HBA9
IPRVLDMLRQQRMML

PTPN21

1136

Q16825
MKMMLVRRFRVLILM

FAM20C

1

Q8IXL6
QLCAKMMRMRTREEM

CEP95

676

Q96GE4
ANMRRTLMERVQRMM

DNAH9

986

Q9NYC9
TLMMEQRSQMLRHMR

SLC12A6

991

Q9UHW9
MMMNLYNAMAVRIQR

SPATA17

86

Q96L03
MMLRLLREQRMFMIQ

PTPN14

1151

Q15678
TLMMEQRSQMLRQMR

SLC12A4

926

Q9UP95
LEVMRMNRICRMVLA

CHST11

6

Q9NPF2
MQRMEVQRRRMMQHP

RNF111

751

Q6ZNA4
LLMKFSRRMAIMNNM

UGT1A5

106

P35504