Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled serotonin receptor activity	HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 HRH2	8.21e-11	22	134	7	GO:0004993
GeneOntologyMolecularFunction	G protein-coupled amine receptor activity	HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 ADRA1A HRH2	2.64e-10	41	134	8	GO:0008227
GeneOntologyMolecularFunction	G protein-coupled receptor activity	XCR1 HTR1B HTR1D GPR18 HTR1E HTR1F MRGPRE GPR84 OR2J3 GPR101 CHRM2 CHRM5 ADRA1A CXCR6 GPR158 OR51Q1 MRGPRG HRH2 CCR1 CCR5 GPRC5D TAS2R45 TAS2R43 TAS2R50 CNR2	9.13e-10	884	134	25	GO:0004930
GeneOntologyMolecularFunction	neurotransmitter receptor activity	GABRG2 HTR1B HTR1D HTR1E HTR1F GRIK4 CHRM2 CHRM5 GPR158 HRH2	1.37e-09	100	134	10	GO:0030594
GeneOntologyMolecularFunction	transmembrane transporter activity	GABRG2 ABCC3 CACNA2D1 HTR1B CACNA2D2 ABCA13 SPNS2 SLC25A14 GRIK4 PKD1L2 SLC44A4 CHRM5 ABCC6 SLC5A2 ABCB4 SLC6A9 SLC9C1 PIEZO2 SLC50A1 SLC18A1 SLC22A14 SV2C SLC38A11 SLC45A1 STRA6 SLC37A4 SLC27A4 SLC22A31	3.89e-09	1180	134	28	GO:0022857
GeneOntologyMolecularFunction	transporter activity	GABRG2 ABCC3 CACNA2D1 HTR1B CACNA2D2 ABCA13 SPNS2 SLC25A14 GRIK4 ATP8B1 PKD1L2 SLC44A4 CHRM5 ABCC6 SLC5A2 ABCB4 SLC6A9 SLC9C1 PIEZO2 SLC50A1 SLC18A1 SLC22A14 SV2C SLC38A11 SLC45A1 STRA6 SLC37A4 SLC27A4 SLC22A31	6.44e-09	1289	134	29	GO:0005215
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	GABRG2 XCR1 HTR1B HTR1D GPR18 HTR1E HTR1F MRGPRE GPR84 OR2J3 GRIK4 GPR101 CHRM2 CHRM5 IFNLR1 LRP8 ADRA1A CXCR6 GPR158 OR51Q1 MRGPRG HRH2 CCR1 CCR5 GPRC5D TAS2R45 TAS2R43 TAS2R50 CNR2	1.89e-08	1353	134	29	GO:0004888
GeneOntologyMolecularFunction	serotonin binding	HTR1B HTR1D HTR1E HTR1F	1.32e-06	13	134	4	GO:0051378
GeneOntologyMolecularFunction	amine binding	HTR1B HTR1D HTR1E HTR1F	1.06e-05	21	134	4	GO:0043176
GeneOntologyMolecularFunction	C-C chemokine receptor activity	XCR1 CXCR6 CCR1 CCR5	1.56e-05	23	134	4	GO:0016493
GeneOntologyMolecularFunction	C-C chemokine binding	XCR1 CXCR6 CCR1 CCR5	1.86e-05	24	134	4	GO:0019957
GeneOntologyMolecularFunction	phosphatidylinositol phospholipase C activity	CHRM5 GDPD5 CCR1 CCR5	2.58e-05	26	134	4	GO:0004435
GeneOntologyMolecularFunction	G protein-coupled chemoattractant receptor activity	XCR1 CXCR6 CCR1 CCR5	2.58e-05	26	134	4	GO:0001637
GeneOntologyMolecularFunction	chemokine receptor activity	XCR1 CXCR6 CCR1 CCR5	2.58e-05	26	134	4	GO:0004950
GeneOntologyMolecularFunction	mannosyltransferase activity	POMT2 TMTC3 ALG3 PIGM	3.50e-05	28	134	4	GO:0000030
GeneOntologyMolecularFunction	phospholipase C activity	CHRM5 GDPD5 CCR1 CCR5	4.04e-05	29	134	4	GO:0004629
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	GABRG2 ABCC3 CACNA2D1 HTR1B CACNA2D2 SLC25A14 GRIK4 PKD1L2 CHRM5 ABCC6 SLC5A2 SLC6A9 SLC9C1 SLC18A1 SLC45A1 SLC37A4	4.97e-05	758	134	16	GO:0015318
GeneOntologyMolecularFunction	chemokine binding	XCR1 CXCR6 CCR1 CCR5	6.82e-05	33	134	4	GO:0019956
GeneOntologyMolecularFunction	G protein-coupled neurotransmitter receptor activity	CHRM2 CHRM5 GPR158	8.05e-05	13	134	3	GO:0099528
GeneOntologyMolecularFunction	active transmembrane transporter activity	ABCC3 ABCA13 SLC25A14 SLC44A4 ABCC6 SLC5A2 ABCB4 SLC6A9 SLC9C1 SLC18A1 SLC45A1 SLC37A4	9.09e-05	477	134	12	GO:0022804
GeneOntologyMolecularFunction	glucoside transmembrane transporter activity	SLC5A2 SLC50A1	1.34e-04	3	134	2	GO:0042947
GeneOntologyMolecularFunction	chemokine (C-C motif) ligand 5 binding	CCR1 CCR5	1.34e-04	3	134	2	GO:0071791
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	GABRG2 ABCC3 SLC25A14 CHRM5 ABCC6 SLC18A1 SLC37A4	1.57e-04	171	134	7	GO:0015103
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC3 ABCA13 ABCC6 ABCB4	3.25e-04	49	134	4	GO:0140359
GeneOntologyMolecularFunction	lipid transporter activity	ABCC3 ABCA13 SPNS2 ATP8B1 ABCB4 STRA6 SLC27A4	3.62e-04	196	134	7	GO:0005319
GeneOntologyMolecularFunction	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	STT3A STT3B	4.41e-04	5	134	2	GO:0004579
GeneOntologyMolecularFunction	oligosaccharyl transferase activity	STT3A STT3B	4.41e-04	5	134	2	GO:0004576
GeneOntologyMolecularFunction	cytokine receptor activity	XCR1 IFNLR1 CXCR6 CCR1 CCR5	4.96e-04	97	134	5	GO:0004896
GeneOntologyMolecularFunction	carbohydrate derivative transmembrane transporter activity	ABCC3 SLC5A2 SLC50A1 SLC37A4	6.63e-04	59	134	4	GO:1901505
GeneOntologyMolecularFunction	bitter taste receptor activity	TAS2R45 TAS2R43 TAS2R50	7.68e-04	27	134	3	GO:0033038
GeneOntologyMolecularFunction	ATP hydrolysis activity	DHX36 ABCC3 SPG7 ABCA13 RNF213 ATP8B1 ABCC6 DHX9 ABCB4 SMARCA4	7.96e-04	441	134	10	GO:0016887
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	ABCC3 GRIK4 SLC44A4 SLC6A9 SLC22A14 SLC38A11 SLC37A4 SLC27A4	8.25e-04	293	134	8	GO:0008514
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC25A14 SLC44A4 SLC5A2 SLC6A9 SLC9C1 SLC18A1 SLC45A1 SLC37A4	8.82e-04	296	134	8	GO:0015291
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	GABRG2 CACNA2D1 HTR1B CACNA2D2 SLC25A14 GRIK4 PKD1L2 CHRM5 SLC5A2 SLC6A9 SLC9C1 PIEZO2 SLC18A1 SLC45A1	9.01e-04	793	134	14	GO:0015075
GeneOntologyMolecularFunction	G protein-coupled acetylcholine receptor activity	CHRM2 CHRM5	9.18e-04	7	134	2	GO:0016907
GeneOntologyMolecularFunction	sugar transmembrane transporter activity	SLC5A2 SLC50A1 SLC45A1	9.50e-04	29	134	3	GO:0051119
GeneOntologyMolecularFunction	phospholipase activity	PLA2G15 CHRM5 GDPD5 CCR1 CCR5	1.03e-03	114	134	5	GO:0004620
GeneOntologyMolecularFunction	ABC-type glutathione S-conjugate transporter activity	ABCC3 ABCC6	1.22e-03	8	134	2	GO:0015431
GeneOntologyMolecularFunction	dolichyl-phosphate-mannose-protein mannosyltransferase activity	POMT2 TMTC3	1.22e-03	8	134	2	GO:0004169
GeneOntologyMolecularFunction	phosphatidylcholine floppase activity	ATP8B1 ABCB4	1.22e-03	8	134	2	GO:0090554
GeneOntologyMolecularFunction	taste receptor activity	TAS2R45 TAS2R43 TAS2R50	1.39e-03	33	134	3	GO:0008527
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	ABCC3 ABCC6 SLC18A1	1.52e-03	34	134	3	GO:0042910
GeneOntologyMolecularFunction	postsynaptic neurotransmitter receptor activity	GABRG2 GRIK4 CHRM2 CHRM5	1.63e-03	75	134	4	GO:0098960
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA2D1 HTR1B CACNA2D2 SLC25A14 GRIK4 PKD1L2 SLC5A2 SLC6A9 SLC9C1 PIEZO2 SLC18A1 SLC45A1	1.74e-03	664	134	12	GO:0008324
GeneOntologyMolecularFunction	vitamin transmembrane transporter activity	SLC44A4 SLC22A14 STRA6	1.79e-03	36	134	3	GO:0090482
GeneOntologyMolecularFunction	double-stranded RNA binding	DHX36 DHX9 RFTN1 CLTC	1.88e-03	78	134	4	GO:0003725
GeneOntologyMolecularFunction	ATPase-coupled inorganic anion transmembrane transporter activity	ABCC3 ABCC6	1.94e-03	10	134	2	GO:0043225
GeneOntologyMolecularFunction	lipase activity	PLA2G15 CHRM5 GDPD5 CCR1 CCR5	2.40e-03	138	134	5	GO:0016298
GeneOntologyMolecularFunction	antiporter activity	SLC25A14 SLC44A4 SLC9C1 SLC18A1 SLC37A4	2.40e-03	138	134	5	GO:0015297
GeneOntologyMolecularFunction	carbohydrate transmembrane transporter activity	SLC5A2 SLC50A1 SLC45A1	2.80e-03	42	134	3	GO:0015144
GeneOntologyMolecularFunction	nuclear export signal receptor activity	XPO4 CSE1L	2.82e-03	12	134	2	GO:0005049
GeneOntologyMolecularFunction	ATP-dependent activity	DHX36 ABCC3 SPG7 ABCA13 RNF213 ATP8B1 ABCC6 DHX9 ABCB4 SMARCA4 SLC27A4	2.88e-03	614	134	11	GO:0140657
GeneOntologyMolecularFunction	hexosyltransferase activity	POMT2 STT3A STT3B TMTC3 ALG3 PIGM	3.04e-03	211	134	6	GO:0016758
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA2D1 HTR1B CACNA2D2 SLC25A14 GRIK4 PKD1L2 SLC5A2 SLC6A9 SLC9C1 SLC18A1 SLC45A1	3.38e-03	627	134	11	GO:0022890
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA2D1 HTR1B CACNA2D2	3.63e-03	46	134	3	GO:0005245
GeneOntologyMolecularFunction	monoatomic ion channel activity	GABRG2 CACNA2D1 HTR1B CACNA2D2 GRIK4 PKD1L2 CHRM5 SLC9C1 PIEZO2	3.85e-03	459	134	9	GO:0005216
GeneOntologyMolecularFunction	phosphoric diester hydrolase activity	CHRM5 GDPD5 CCR1 CCR5	4.15e-03	97	134	4	GO:0008081
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA2D1 HTR1B CACNA2D2 GRIK4 PKD1L2 SLC5A2 SLC6A9 SLC9C1 SLC18A1	4.19e-03	465	134	9	GO:0046873
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCC3 ABCC6	4.43e-03	15	134	2	GO:0008559
GeneOntologyMolecularFunction	floppase activity	ATP8B1 ABCB4	5.04e-03	16	134	2	GO:0140328
GeneOntologyMolecularFunction	immune receptor activity	XCR1 IFNLR1 CXCR6 CCR1 CCR5	5.15e-03	165	134	5	GO:0140375
GeneOntologyMolecularFunction	carbohydrate:monoatomic cation symporter activity	SLC5A2 SLC45A1	5.69e-03	17	134	2	GO:0005402
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	GRIK4 SLC5A2 SLC6A9 SLC9C1 SLC18A1	5.97e-03	171	134	5	GO:0015081
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCC3 ABCA13 ABCC6 ABCB4	6.27e-03	109	134	4	GO:0042626
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	XCR1 HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 HRH2 CCR1 CNR2	6.02e-12	61	133	10	GO:0007187
GeneOntologyBiologicalProcess	G protein-coupled serotonin receptor signaling pathway	HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 HRH2	8.89e-11	23	133	7	GO:0098664
GeneOntologyBiologicalProcess	anterograde trans-synaptic signaling	GABRG2 HTR1B HTR1D HTR1E HTR1F PSEN2 CACNA2D2 CNIH2 TSC2 GRIK4 LRRC4 CHRM2 CHRM5 CNIH3 LRP8 SLC6A9 ADRA1A GPR158 ATXN3 HRH2 SV2C FER1L5 CNR2	2.77e-08	931	133	23	GO:0098916
GeneOntologyBiologicalProcess	chemical synaptic transmission	GABRG2 HTR1B HTR1D HTR1E HTR1F PSEN2 CACNA2D2 CNIH2 TSC2 GRIK4 LRRC4 CHRM2 CHRM5 CNIH3 LRP8 SLC6A9 ADRA1A GPR158 ATXN3 HRH2 SV2C FER1L5 CNR2	2.77e-08	931	133	23	GO:0007268
GeneOntologyBiologicalProcess	trans-synaptic signaling	GABRG2 HTR1B HTR1D HTR1E HTR1F PSEN2 CACNA2D2 CNIH2 TSC2 GRIK4 LRRC4 CHRM2 CHRM5 CNIH3 LRP8 SLC6A9 ADRA1A GPR158 ATXN3 HRH2 SV2C FER1L5 CNR2	3.24e-08	939	133	23	GO:0099537
GeneOntologyBiologicalProcess	adenylate cyclase-inhibiting serotonin receptor signaling pathway	HTR1B HTR1D HTR1E HTR1F	5.70e-08	7	133	4	GO:0007198
GeneOntologyBiologicalProcess	synaptic signaling	GABRG2 HTR1B HTR1D HTR1E HTR1F PSEN2 CACNA2D2 CNIH2 TSC2 GRIK4 LRRC4 CHRM2 CHRM5 CNIH3 LRP8 SLC6A9 ADRA1A GPR158 ATXN3 HRH2 SV2C FER1L5 CNR2	6.55e-08	976	133	23	GO:0099536
GeneOntologyBiologicalProcess	monoatomic ion transport	GABRG2 ABCC3 XCR1 CACNA2D1 HTR1B ZMPSTE24 SPG7 PSEN2 CACNA2D2 WFS1 SLC25A14 GRIK4 ATP8B1 PKD1L2 ABCC6 SLC5A2 TG SLC6A9 SLC9C1 ADRA1A PIEZO2 SLC18A1 CLTC CCR1 CCR5 SLC38A11 SLC22A31	1.66e-07	1374	133	27	GO:0006811
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	XCR1 HTR1B HTR1D GPR18 HTR1E HTR1F SPNS2 MRGPRE GPR84 OR2J3 GPR101 CHRM2 CHRM5 ADRA1A CXCR6 GPR158 OR51Q1 MRGPRG HRH2 CCR1 CCR5 GPRC5D TAS2R45 TAS2R43 TAS2R50 CNR2 ECE2	2.24e-07	1395	133	27	GO:0007186
GeneOntologyBiologicalProcess	glycoside transport	ABCC3 SLC5A2 SLC50A1	2.60e-06	5	133	3	GO:1901656
GeneOntologyBiologicalProcess	xenobiotic transmembrane transport	ABCC3 ATP8B1 ABCC6 ABCB4	5.94e-06	19	133	4	GO:0006855
GeneOntologyBiologicalProcess	organic anion transport	CLN8 ABCC3 HTR1B ATP8B1 SLC44A4 ABCC6 PLIN2 ABCB4 SLC6A9 SLC22A14 HRH2 SLC38A11 SLC37A4 SLC27A4	6.21e-06	515	133	14	GO:0015711
GeneOntologyBiologicalProcess	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5	1.98e-05	86	133	6	GO:0007193
GeneOntologyBiologicalProcess	modulation of chemical synaptic transmission	HTR1B HTR1D PSEN2 CACNA2D2 GRIK4 LRRC4 CHRM2 LRP8 SLC6A9 ADRA1A GPR158 HRH2 SV2C FER1L5 CNR2	2.51e-05	663	133	15	GO:0050804
GeneOntologyBiologicalProcess	regulation of trans-synaptic signaling	HTR1B HTR1D PSEN2 CACNA2D2 GRIK4 LRRC4 CHRM2 LRP8 SLC6A9 ADRA1A GPR158 HRH2 SV2C FER1L5 CNR2	2.55e-05	664	133	15	GO:0099177
GeneOntologyBiologicalProcess	xenobiotic transport	ABCC3 ATP8B1 ABCC6 ABCB4 SLC18A1	5.81e-05	64	133	5	GO:0042908
GeneOntologyBiologicalProcess	carboxylic acid transport	CLN8 ABCC3 HTR1B ATP8B1 ABCC6 PLIN2 ABCB4 SLC6A9 HRH2 SLC38A11 SLC27A4	7.21e-05	410	133	11	GO:0046942
GeneOntologyBiologicalProcess	organic acid transport	CLN8 ABCC3 HTR1B ATP8B1 ABCC6 PLIN2 ABCB4 SLC6A9 HRH2 SLC38A11 SLC27A4	7.53e-05	412	133	11	GO:0015849
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	GABRG2 ABCC3 XCR1 CACNA2D1 SPG7 PSEN2 CACNA2D2 SLC25A14 GRIK4 ATP8B1 PKD1L2 ABCC6 SLC5A2 SLC6A9 SLC9C1 ADRA1A PIEZO2 SLC18A1 CCR5	9.84e-05	1115	133	19	GO:0034220
GeneOntologyBiologicalProcess	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	HTR1B HTR1D HTR1E HTR1F GPR101 CHRM2 CHRM5 ADRA1A CNR2	1.01e-04	286	133	9	GO:0007188
GeneOntologyBiologicalProcess	co-translational protein modification	STT3A STT3B	1.23e-04	3	133	2	GO:0043686
GeneOntologyBiologicalProcess	glucoside transport	SLC5A2 SLC50A1	1.23e-04	3	133	2	GO:0042946
GeneOntologyBiologicalProcess	monoatomic cation transport	XCR1 CACNA2D1 ZMPSTE24 SPG7 PSEN2 CACNA2D2 WFS1 SLC25A14 PKD1L2 SLC5A2 SLC6A9 SLC9C1 ADRA1A PIEZO2 SLC18A1 CLTC CCR1 CCR5 SLC38A11	1.59e-04	1157	133	19	GO:0006812
GeneOntologyBiologicalProcess	neurotransmitter transport	CLN8 HTR1B HTR1D SLC6A9 GPR158 SLC18A1 SV2C FER1L5	2.82e-04	259	133	8	GO:0006836
GeneOntologyBiologicalProcess	regulation of neurotransmitter transport	HTR1B HTR1D GPR158 SLC18A1 SV2C FER1L5	3.09e-04	141	133	6	GO:0051588
GeneOntologyBiologicalProcess	carbohydrate derivative transport	ABCC3 ABCC6 SLC5A2 SLC50A1 SLC37A4	3.95e-04	96	133	5	GO:1901264
GeneOntologyBiologicalProcess	calcium ion transport	XCR1 CACNA2D1 ZMPSTE24 SPG7 PSEN2 CACNA2D2 WFS1 PKD1L2 ADRA1A CCR1 CCR5	4.67e-04	509	133	11	GO:0006816
GeneOntologyBiologicalProcess	regulation of neurotransmitter receptor activity	CNIH2 CNIH3 LRP8 SLC6A9	4.68e-04	56	133	4	GO:0099601
GeneOntologyBiologicalProcess	acid secretion	HTR1B CHRM5 ABCB4 HRH2	5.01e-04	57	133	4	GO:0046717
GeneOntologyCellularComponent	dendrite	GABRG2 DHX36 BRINP3 HTR1B HTR1D HTR1E HTR1F WFS1 CNIH2 ARFGEF2 TSC2 GRIK4 LRRC4 CHRM2 CHRM5 CNIH3 LRP8 HRH2 RTN4RL2 CNR2	8.21e-07	858	137	20	GO:0030425
GeneOntologyCellularComponent	dendritic tree	GABRG2 DHX36 BRINP3 HTR1B HTR1D HTR1E HTR1F WFS1 CNIH2 ARFGEF2 TSC2 GRIK4 LRRC4 CHRM2 CHRM5 CNIH3 LRP8 HRH2 RTN4RL2 CNR2	8.51e-07	860	137	20	GO:0097447
GeneOntologyCellularComponent	endoplasmic reticulum membrane	POMT2 CLN8 ZMPSTE24 PSEN2 WFS1 CNIH2 CERS6 CYP39A1 ABCC6 CNIH3 STT3A STT3B GDPD5 HSD3B7 RNF103 SLC18A1 ATXN3 PIGW ALG3 SELENOI ALDH3A2 SLC37A4 SLC27A4 PIGM RNF26	9.71e-07	1293	137	25	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	POMT2 CLN8 ZMPSTE24 PSEN2 WFS1 CNIH2 CERS6 CYP39A1 ABCC6 CNIH3 STT3A STT3B GDPD5 HSD3B7 RNF103 SLC18A1 ATXN3 PIGW ALG3 SELENOI ALDH3A2 SLC37A4 SLC27A4 PIGM RNF26	1.06e-06	1299	137	25	GO:0098827
GeneOntologyCellularComponent	synaptic membrane	GABRG2 CACNA2D1 HTR1B PSEN2 CACNA2D2 CNIH2 GRIK4 LRRC4 CHRM2 CHRM5 CNIH3 LRP8 SLC6A9 ADRA1A GPR158 CLTC	1.43e-06	583	137	16	GO:0097060
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	POMT2 CLN8 ZMPSTE24 PSEN2 WFS1 CNIH2 CERS6 CYP39A1 ABCC6 CNIH3 STT3A STT3B GDPD5 HSD3B7 RNF103 SLC18A1 ATXN3 PIGW ALG3 SELENOI ALDH3A2 SLC37A4 SLC27A4 PIGM RNF26	1.55e-06	1327	137	25	GO:0042175
GeneOntologyCellularComponent	somatodendritic compartment	GABRG2 DHX36 BRINP3 HTR1B HTR1D HTR1E HTR1F PSEN2 WFS1 CNIH2 ARFGEF2 TSC2 GRIK4 LRRC4 CHRM2 CHRM5 CNIH3 LRP8 GDPD5 HRH2 CCR1 RTN4RL2 CNR2	4.78e-06	1228	137	23	GO:0036477
GeneOntologyCellularComponent	presynaptic membrane	CACNA2D1 HTR1B PSEN2 CACNA2D2 GRIK4 CHRM2 SLC6A9 ADRA1A GPR158 CLTC	1.48e-05	277	137	10	GO:0042734
GeneOntologyCellularComponent	postsynaptic membrane	GABRG2 CACNA2D1 CNIH2 GRIK4 LRRC4 CHRM2 CHRM5 CNIH3 LRP8 SLC6A9 ADRA1A GPR158	1.50e-05	405	137	12	GO:0045211
GeneOntologyCellularComponent	transport vesicle membrane	WFS1 CNIH2 CNIH3 SLC6A9 SLC18A1 CLTC SV2C FER1L5 ECE2	1.38e-04	293	137	9	GO:0030658
GeneOntologyCellularComponent	presynapse	CLN8 CACNA2D1 HTR1B PSEN2 CACNA2D2 WFS1 ARFGEF2 GRIK4 CHRM2 SLC6A9 ADRA1A GPR158 SLC18A1 CLTC SV2C FER1L5	2.31e-04	886	137	16	GO:0098793
GeneOntologyCellularComponent	glutamatergic synapse	GABRG2 CACNA2D1 HTR1D PSEN2 CNIH2 ARFGEF2 TSC2 GRIK4 LRRC4 CHRM2 CNIH3 LRP8 ADRA1A CLTC	9.63e-04	817	137	14	GO:0098978
GeneOntologyCellularComponent	perichromatin fibrils	DHX9 SMARCA4	1.16e-03	8	137	2	GO:0005726
GeneOntologyCellularComponent	exocytic vesicle membrane	WFS1 SLC6A9 SLC18A1 CLTC SV2C FER1L5	1.18e-03	179	137	6	GO:0099501
GeneOntologyCellularComponent	synaptic vesicle membrane	WFS1 SLC6A9 SLC18A1 CLTC SV2C FER1L5	1.18e-03	179	137	6	GO:0030672
GeneOntologyCellularComponent	T-tubule	CACNA2D1 ADRA1A CLTC FER1L5	1.81e-03	79	137	4	GO:0030315
GeneOntologyCellularComponent	nuclear pore outer ring	NUP133 NUP160	1.85e-03	10	137	2	GO:0031080
GeneOntologyCellularComponent	postsynaptic specialization membrane	GABRG2 CNIH2 GRIK4 LRRC4 LRP8 GPR158	2.13e-03	201	137	6	GO:0099634
GeneOntologyCellularComponent	transport vesicle	PSEN2 WFS1 CNIH2 CNIH3 SLC6A9 SLC18A1 CLTC SV2C FER1L5 ECE2	2.25e-03	519	137	10	GO:0030133
GeneOntologyCellularComponent	motile cilium	SPAG4 SLC9C1 SLC22A14 CFAP20 NME5 TAS2R45 TAS2R43 TAS2R50	2.40e-03	355	137	8	GO:0031514
GeneOntologyCellularComponent	postsynapse	GABRG2 CACNA2D1 CNIH2 ARFGEF2 TSC2 GRIK4 LRRC4 CHRM2 CHRM5 CNIH3 LRP8 SLC6A9 ADRA1A GPR158 CLTC	2.80e-03	1018	137	15	GO:0098794
GeneOntologyCellularComponent	symmetric synapse	ARFGEF2 CHRM2	3.17e-03	13	137	2	GO:0032280
GeneOntologyCellularComponent	ionotropic glutamate receptor complex	CNIH2 GRIK4 CNIH3	3.20e-03	45	137	3	GO:0008328
GeneOntologyCellularComponent	synaptic vesicle	PSEN2 WFS1 SLC6A9 SLC18A1 CLTC SV2C FER1L5	3.68e-03	300	137	7	GO:0008021
GeneOntologyCellularComponent	oligosaccharyltransferase complex	STT3A STT3B	3.68e-03	14	137	2	GO:0008250
GeneOntologyCellularComponent	postsynaptic density membrane	CNIH2 GRIK4 LRRC4 LRP8 GPR158	3.78e-03	157	137	5	GO:0098839
Domain	GPCR_Rhodpsn_7TM	XCR1 HTR1B HTR1D GPR18 HTR1E HTR1F MRGPRE GPR84 OR2J3 GPR101 CHRM2 CHRM5 ADRA1A CXCR6 OR51Q1 MRGPRG HRH2 CCR1 CCR5 CNR2	6.55e-08	670	134	20	IPR017452
Domain	7tm_1	XCR1 HTR1B HTR1D GPR18 HTR1E HTR1F MRGPRE GPR84 OR2J3 GPR101 CHRM2 CHRM5 ADRA1A CXCR6 OR51Q1 MRGPRG HRH2 CCR1 CCR5 CNR2	7.76e-08	677	134	20	PF00001
Domain	G_PROTEIN_RECEP_F1_1	XCR1 HTR1B HTR1D GPR18 HTR1E HTR1F MRGPRE GPR84 OR2J3 GPR101 CHRM2 CHRM5 ADRA1A CXCR6 OR51Q1 MRGPRG HRH2 CCR1 CCR5 CNR2	9.38e-08	685	134	20	PS00237
Domain	G_PROTEIN_RECEP_F1_2	XCR1 HTR1B HTR1D GPR18 HTR1E HTR1F MRGPRE GPR84 OR2J3 GPR101 CHRM2 CHRM5 ADRA1A CXCR6 OR51Q1 MRGPRG HRH2 CCR1 CCR5 CNR2	1.08e-07	691	134	20	PS50262
Domain	GPCR_Rhodpsn	XCR1 HTR1B HTR1D GPR18 HTR1E HTR1F MRGPRE GPR84 OR2J3 GPR101 CHRM2 CHRM5 ADRA1A CXCR6 OR51Q1 MRGPRG HRH2 CCR1 CCR5 CNR2	1.11e-07	692	134	20	IPR000276
Domain	7TM_GPCR_Srsx	HTR1B HTR1D HTR1E HTR1F CHRM2 ADRA1A HRH2 CCR1 CNR2	1.13e-07	112	134	9	SM01381
Domain	5HT_rcpt	HTR1B HTR1D HTR1E HTR1F	3.10e-07	9	134	4	IPR002231
Domain	MFS_1	SPNS2 SLC18A1 SLC22A14 SV2C SLC45A1 SLC37A4	1.90e-05	77	134	6	PF07690
Domain	MFS	SPNS2 SLC18A1 SLC22A14 SV2C SLC45A1 SLC37A4	1.90e-05	77	134	6	IPR011701
Domain	5HT1F_rcpt	HTR1E HTR1F	5.11e-05	2	134	2	IPR000450
Domain	STT3	STT3A STT3B	5.11e-05	2	134	2	PF02516
Domain	Oligo_trans_STT3	STT3A STT3B	5.11e-05	2	134	2	IPR003674
Domain	MFS	SPNS2 SLC18A1 SLC22A14 SV2C SLC37A4 SLC22A31	1.28e-04	108	134	6	PS50850
Domain	Cornichon_conserved	CNIH2 CNIH3	1.53e-04	3	134	2	IPR033466
Domain	CORNICHON	CNIH2 CNIH3	1.53e-04	3	134	2	PS01340
Domain	Chemokine_rcpt	CXCR6 CCR1 CCR5	1.89e-04	16	134	3	IPR000355
Domain	VGCC_alpha2	CACNA2D1 CACNA2D2	3.04e-04	4	134	2	PF08473
Domain	VDCC_a2/dsu	CACNA2D1 CACNA2D2	3.04e-04	4	134	2	IPR013680
Domain	Multidrug-R_assoc	ABCC3 ABCC6	3.04e-04	4	134	2	IPR005292
Domain	Cornichon	CNIH2 CNIH3	3.04e-04	4	134	2	PF03311
Domain	Cornichon	CNIH2 CNIH3	3.04e-04	4	134	2	IPR003377
Domain	Cornichon	CNIH2 CNIH3	3.04e-04	4	134	2	SM01398
Domain	ABC_tran	ABCC3 ABCA13 ABCC6 ABCB4	3.86e-04	48	134	4	PF00005
Domain	ABC_TRANSPORTER_2	ABCC3 ABCA13 ABCC6 ABCB4	3.86e-04	48	134	4	PS50893
Domain	MFS_dom	SPNS2 SLC18A1 SLC22A14 SV2C SLC37A4 SLC22A31	4.13e-04	134	134	6	IPR020846
Domain	ABC_TRANSPORTER_1	ABCC3 ABCA13 ABCC6 ABCB4	4.18e-04	49	134	4	PS00211
Domain	ABC_transporter-like	ABCC3 ABCA13 ABCC6 ABCB4	4.52e-04	50	134	4	IPR003439
Domain	VWA_N	CACNA2D1 CACNA2D2	5.04e-04	5	134	2	IPR013608
Domain	Musac_Ach_rcpt	CHRM2 CHRM5	5.04e-04	5	134	2	IPR000995
Domain	VWA_N	CACNA2D1 CACNA2D2	5.04e-04	5	134	2	PF08399
Domain	AAA+_ATPase	ABCC3 SPG7 ABCA13 RNF213 ABCC6 ABCB4	6.05e-04	144	134	6	IPR003593
Domain	AAA	ABCC3 SPG7 ABCA13 RNF213 ABCC6 ABCB4	6.05e-04	144	134	6	SM00382
Domain	ABC_membrane	ABCC3 ABCC6 ABCB4	6.55e-04	24	134	3	PF00664
Domain	TAS2R	TAS2R45 TAS2R43 TAS2R50	8.32e-04	26	134	3	PF05296
Domain	T2R	TAS2R45 TAS2R43 TAS2R50	8.32e-04	26	134	3	IPR007960
Domain	ABC_TM1F	ABCC3 ABCC6 ABCB4	1.04e-03	28	134	3	PS50929
Domain	ABC1_TM_dom	ABCC3 ABCC6 ABCB4	1.04e-03	28	134	3	IPR011527
Domain	MFS_sugar_transport-like	SLC22A14 SV2C SLC22A31	2.17e-03	36	134	3	IPR005828
Domain	Sugar_tr	SLC22A14 SV2C SLC22A31	2.17e-03	36	134	3	PF00083
Domain	MRGPCRFAMILY	MRGPRE MRGPRG	2.69e-03	11	134	2	IPR026234
Domain	ABC_transporter_CS	ABCC3 ABCC6 ABCB4	3.38e-03	42	134	3	IPR017871
Domain	Carboxylesterase_B_CS	TG CES4A	3.78e-03	13	134	2	IPR019819
Domain	CARBOXYLESTERASE_B_2	TG CES4A	4.39e-03	14	134	2	PS00941
Domain	COesterase	TG CES4A	4.39e-03	14	134	2	PF00135
Domain	CarbesteraseB	TG CES4A	4.39e-03	14	134	2	IPR002018
Domain	TLC	CLN8 CERS6	5.74e-03	16	134	2	PS50922
Domain	TLC	CLN8 CERS6	5.74e-03	16	134	2	SM00724
Domain	TRAM_LAG1_CLN8	CLN8 CERS6	5.74e-03	16	134	2	PF03798
Domain	TLC-dom	CLN8 CERS6	5.74e-03	16	134	2	IPR006634
Domain	DUF1605	DHX36 DHX9	6.48e-03	17	134	2	IPR011709
Domain	OB_NTP_bind	DHX36 DHX9	6.48e-03	17	134	2	PF07717
Pathway	WP_MONOAMINE_GPCRS	HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 ADRA1A HRH2	1.35e-10	33	111	8	M39585
Pathway	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 ADRA1A HRH2	1.08e-09	42	111	8	M5868
Pathway	WP_MONOAMINE_GPCRS	HTR1B HTR1D HTR1F CHRM2 CHRM5 ADRA1A HRH2	3.49e-09	31	111	7	MM15871
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	XCR1 HTR1B HTR1D GPR18 HTR1E HTR1F OR2J3 CHRM2 CHRM5 ADRA1A HRH2 CCR1 CCR5 CNR2	1.59e-08	260	111	14	M39397
Pathway	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	HTR1B HTR1D HTR1F CHRM2 CHRM5 ADRA1A HRH2	3.33e-08	42	111	7	MM14971
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	XCR1 HTR1B HTR1D GPR18 HTR1E HTR1F CHRM2 CHRM5 ADRA1A CXCR6 HRH2 CCR1 CCR5 CNR2 ECE2	4.51e-08	330	111	15	M18334
Pathway	REACTOME_GPCR_LIGAND_BINDING	XCR1 HTR1B HTR1D GPR18 HTR1E HTR1F CHRM2 CHRM5 ADRA1A CXCR6 HRH2 CCR1 CCR5 TAS2R43 TAS2R50 CNR2 ECE2	1.19e-07	463	111	17	M507
Pathway	WP_GPCRS_NONODORANT	XCR1 HTR1B HTR1D GPR18 HTR1F CHRM2 CHRM5 ADRA1A CXCR6 HRH2 CCR1 GPRC5D CNR2	1.66e-07	266	111	13	MM15843
Pathway	REACTOME_GPCR_LIGAND_BINDING	XCR1 HTR1B HTR1D GPR18 HTR1F CHRM2 CHRM5 ADRA1A CXCR6 HRH2 CCR5 TAS2R45 TAS2R43 TAS2R50 CNR2 ECE2	2.44e-07	430	111	16	MM15160
Pathway	REACTOME_SEROTONIN_RECEPTORS	HTR1B HTR1D HTR1E HTR1F	1.72e-06	12	111	4	M6034
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	XCR1 HTR1B HTR1D GPR18 HTR1F CHRM2 CHRM5 ADRA1A CXCR6 HRH2 CCR5 CNR2 ECE2	2.11e-06	333	111	13	MM14963
Pathway	REACTOME_SIGNALING_BY_GPCR	XCR1 HTR1B HTR1D GPR18 HTR1F GPR84 CHRM2 CHRM5 ADRA1A CXCR6 HRH2 CCR1 CCR5 TAS2R45 TAS2R43 TAS2R50 CNR2 ECE2	2.75e-06	646	111	18	MM14962
Pathway	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	HTR1B HTR1D GPR18 HTR1F CHRM2 CXCR6 CCR1 CCR5 TAS2R45 TAS2R43 TAS2R50 CNR2	2.84e-06	289	111	12	MM15057
Pathway	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	HTR1B HTR1D GPR18 HTR1E HTR1F CHRM2 CXCR6 CCR1 CCR5 TAS2R43 TAS2R50 CNR2	6.64e-06	314	111	12	M600
Pathway	REACTOME_SIGNALING_BY_GPCR	XCR1 HTR1B HTR1D GPR18 HTR1E HTR1F GPR84 CHRM2 CHRM5 ADRA1A CXCR6 HRH2 CCR1 CCR5 TAS2R43 TAS2R50 CNR2 ECE2	8.72e-06	702	111	18	M746
Pathway	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	GABRG2 HTR1B HTR1D HTR1E HTR1F GRIK4 CHRM2 CHRM5 ADRA1A HRH2 CNR2	9.69e-06	272	111	11	M13380
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	HTR1B HTR1D HTR1F CHRM2 ADRA1A HRH2 CCR1 CCR5 CNR2	1.59e-05	186	111	9	MM15994
Pathway	WP_GPCRS_ODORANT	MRGPRE GPR84 GPR101 GPR158 MRGPRG TAS2R45 TAS2R43 TAS2R50	3.31e-05	157	111	8	MM15872
Pathway	WP_DISORDERS_OF_BILE_ACID_SYNTHESIS_AND_BILIARY_TRANSPORT	ABCC3 ATP8B1 ABCB4 HSD3B7	7.43e-05	29	111	4	M45551
Pathway	REACTOME_SEROTONIN_RECEPTORS	HTR1B HTR1D HTR1F	7.49e-05	11	111	3	MM15008
Pathway	WP_SEROTONIN_HTR1_GROUP_AND_FOS_PATHWAY	HTR1B HTR1D HTR1E HTR1F	1.97e-04	37	111	4	M42558
Pathway	KEGG_ABC_TRANSPORTERS	ABCC3 ABCA13 ABCC6 ABCB4	3.88e-04	44	111	4	M11911
Pathway	WP_CHOLESTASIS	ABCC3 ATP8B1 ABCB4	4.20e-04	19	111	3	M45520
Pathway	REACTOME_MUSCARINIC_ACETYLCHOLINE_RECEPTORS	CHRM2 CHRM5	6.05e-04	5	111	2	M27300
Pathway	REACTOME_MUSCARINIC_ACETYLCHOLINE_RECEPTORS	CHRM2 CHRM5	6.05e-04	5	111	2	MM15006
Pathway	WP_GPCRS_OTHER	GPR18 HTR1F GPR84 CHRM2 CCR5	8.29e-04	93	111	5	M39629
Pathway	BIOCARTA_MRP_PATHWAY	ABCC3 ABCB4	9.03e-04	6	111	2	M22078
Pathway	REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES	XCR1 CXCR6 CCR1 CCR5	1.04e-03	57	111	4	M625
Pathway	REACTOME_DEX_H_BOX_HELICASES_ACTIVATE_TYPE_I_IFN_AND_INFLAMMATORY_CYTOKINES_PRODUCTION	DHX36 DHX9	1.26e-03	7	111	2	MM14930
Pathway	REACTOME_DEX_H_BOX_HELICASES_ACTIVATE_TYPE_I_IFN_AND_INFLAMMATORY_CYTOKINES_PRODUCTION	DHX36 DHX9	1.26e-03	7	111	2	M27227
Pubmed	Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.	HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 ADRA1A CXCR6 HRH2 CCR1 CCR5 CNR2	3.03e-11	200	138	12	18240029
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	POMT2 COL4A4 DHX36 ABCC3 TCTN3 CACNA2D1 ZMPSTE24 WFS1 ARFGEF2 RNF213 TSC2 CERS6 PLA2G15 STT3A STT3B LRP8 TMTC3 EDEM2 ALG3 SELENOI ALDH3A2 SLC37A4	2.30e-09	1201	138	22	35696571
Pubmed	Dissociation of heterotrimeric g proteins in cells.	HTR1B HTR1D GPR18 HTR1E HTR1F CHRM2 CXCR6 CCR1 CCR5 CNR2	2.84e-09	179	138	10	18577758
Pubmed	Suicide and serotonin: study of variation at seven serotonin receptor genes in suicide completers.	HTR1B HTR1D HTR1E HTR1F	8.23e-09	7	138	4	12627464
Pubmed	Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.	HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 SLC18A1 HRH2	2.54e-08	118	138	8	19156168
Pubmed	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	GABRG2 HTR1B HTR1D HTR1E HTR1F TSC2 GRIK4 CHRM2 CHRM5 SLC6A9 ADRA1A	3.57e-08	300	138	11	19086053
Pubmed	5-Hydroxytryptamine(1B/1D) and 5-hydroxytryptamine1F receptors inhibit capsaicin-induced c-fos immunoreactivity within mouse trigeminal nucleus caudalis.	HTR1B HTR1D HTR1F	6.11e-08	3	138	3	12110114
Pubmed	Inflammation-induced hepatocellular carcinoma is dependent on CCR5 in mice.	ABCB4 CCR1 CCR5	6.11e-08	3	138	3	23526353
Pubmed	Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development.	HTR1B HTR1D HTR1F	2.44e-07	4	138	3	16824687
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	DHX36 ABCC3 EFL1 XPO4 TSC2 WDR43 STT3B MST1 SLC6A9 HSD3B7 TLE1 CFAP20 ZNF408 CLTC EDEM2 ALG3 SELENOI STRA6 ALDH3A2 ZRANB1	3.11e-07	1327	138	20	32694731
Pubmed	Structural insights into the ligand binding and Gi coupling of serotonin receptor 5-HT5A.	HTR1B HTR1E HTR1F	6.08e-07	5	138	3	35610220
Pubmed	Genotypes and haplotypes of CCR2 and CCR3 genes in Japanese cedar pollinosis.	XCR1 CCR1 CCR5	6.08e-07	5	138	3	17135764
Pubmed	Comparative human/murine sequence analysis of the common eliminated region 1 from human 3p21.3.	XCR1 CXCR6 CCR1 CCR5	6.95e-07	18	138	4	12461651
Pubmed	Association study of the serotoninergic system in migraine in the Spanish population.	HTR1B HTR1D HTR1E HTR1F	6.95e-07	18	138	4	19455600
Pubmed	Mapping of the CCXCR1, CX3CR1, CCBP2 and CCR9 genes to the CCR cluster within the 3p21.3 region of the human genome.	XCR1 CCR1 CCR5	1.21e-06	6	138	3	10702689
Pubmed	Extreme genetic divergence is required for coreceptor switching in HIV-1 subtype C.	CXCR6 CCR1 CCR5	2.11e-06	7	138	3	20921899
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	ZMPSTE24 XPO4 STT3A STT3B DHX9 CSE1L TMTC3 CLTC NUP133 SMARCA4 ALDH3A2 NUP160 SLC27A4	2.36e-06	657	138	13	36180527
Pubmed	5-hydroxytryptamine produced by enteric serotonergic neurons initiates colorectal cancer stem cell self-renewal and tumorigenesis.	HTR1B HTR1D HTR1F	3.37e-06	8	138	3	35550066
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	POMT2 TCTN3 NDST2 PLA2G15 STT3A STT3B TMTC3	4.40e-06	164	138	7	32409323
Pubmed	Trafficking machinery of NKT cells: shared and differential chemokine receptor expression among V alpha 24(+)V beta 11(+) NKT cell subsets with distinct cytokine-producing capacity.	CXCR6 CCR1 CCR5	5.05e-06	9	138	3	12070001
Pubmed	Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.	HTR1B HTR1E HTR1F CCR1 CCR5	1.26e-05	75	138	5	2834384
Pubmed	A common variant in DRD3 receptor is associated with autism spectrum disorder.	HTR1B HTR1E ABCA13 TSC2 CHRM5 CNR2	1.28e-05	128	138	6	19058789
Pubmed	The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.	TAS2R45 TAS2R43 TAS2R50	1.31e-05	12	138	3	12379855
Pubmed	The phe-124-Cys and A-161T variants of the human 5-HT1B receptor gene are not major determinants of the clinical response to sumatriptan.	HTR1B HTR1D	1.56e-05	2	138	2	17501853
Pubmed	Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers.	HTR1B HTR1D	1.56e-05	2	138	2	1557407
Pubmed	Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture.	TAS2R43 TAS2R50	1.56e-05	2	138	2	33461297
Pubmed	Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells.	HTR1B HTR1D	1.56e-05	2	138	2	25170871
Pubmed	Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.	HTR1B HTR1D	1.56e-05	2	138	2	1652050
Pubmed	Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype.	HTR1E HTR1F	1.56e-05	2	138	2	1608964
Pubmed	Chemokine receptor CCR1 but not CCR5 mediates leukocyte recruitment and subsequent renal fibrosis after unilateral ureteral obstruction.	CCR1 CCR5	1.56e-05	2	138	2	14747380
Pubmed	Mutations in STT3A and STT3B cause two congenital disorders of glycosylation.	STT3A STT3B	1.56e-05	2	138	2	23842455
Pubmed	Quantitative glycoproteomics reveals new classes of STT3A- and STT3B-dependent N-glycosylation sites.	STT3A STT3B	1.56e-05	2	138	2	31296534
Pubmed	ABCB4 missense mutations D243A, K435T, G535D, I490T, R545C, and S978P significantly impair the lipid floppase and likely predispose to secondary pathologies in the human population.	ATP8B1 ABCB4	1.56e-05	2	138	2	28220208
Pubmed	Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells.	HTR1B HTR1D	1.56e-05	2	138	2	25268648
Pubmed	Antitumor effect after radiofrequency ablation of murine hepatoma is augmented by an active variant of CC Chemokine ligand 3/macrophage inflammatory protein-1alpha.	CCR1 CCR5	1.56e-05	2	138	2	20663902
Pubmed	CCR1 and CCR5 expression on inflammatory cells is related to cigarette smoking and chronic obstructive pulmonary disease severity.	CCR1 CCR5	1.56e-05	2	138	2	23217400
Pubmed	MIP-3alpha and MIP-1alpha rapidly mobilize dendritic cell precursors into the peripheral blood.	CCR1 CCR5	1.56e-05	2	138	2	18791167
Pubmed	Chemokine receptor CCR1 disruption limits renal damage in a murine model of hemolytic uremic syndrome.	CCR1 CCR5	1.56e-05	2	138	2	22203055
Pubmed	Na+ -taurocholate cotransporting polypeptide inhibition has hepatoprotective effects in cholestasis in mice.	ATP8B1 ABCB4	1.56e-05	2	138	2	29572910
Pubmed	Molecular cloning and functional characterization of a human 5-HT1B serotonin receptor: a homologue of the rat 5-HT1B receptor with 5-HT1D-like pharmacological specificity.	HTR1B HTR1D	1.56e-05	2	138	2	1315531
Pubmed	Antagonism of RANTES receptors reduces atherosclerotic plaque formation in mice.	CCR1 CCR5	1.56e-05	2	138	2	14656931
Pubmed	Short communication: evidence of HIV type 1 clade C env clones containing low V3 loop charge obtained from an AIDS patient in India that uses CXCR6 and CCR8 for entry in addition to CCR5.	CXCR6 CCR5	1.56e-05	2	138	2	20854195
Pubmed	C-C motif chemokine CCL3 and canonical neutrophil attractants promote neutrophil extravasation through common and distinct mechanisms.	CCR1 CCR5	1.56e-05	2	138	2	22674804
Pubmed	Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships.	HTR1E HTR1F	1.56e-05	2	138	2	21422162
Pubmed	Age-dependent role for CCR5 in antiviral host defense against herpes simplex virus type 2.	CCR1 CCR5	1.56e-05	2	138	2	16014944
Pubmed	Blocking CC chemokine receptor (CCR) 1 and CCR5 during herpes simplex virus type 2 infection in vivo impairs host defence and perturbs the cytokine response.	CCR1 CCR5	1.56e-05	2	138	2	15030585
Pubmed	CC chemokine receptor 5 and CXC chemokine receptor 6 expression by lung CD8+ cells correlates with chronic obstructive pulmonary disease severity.	CXCR6 CCR5	1.56e-05	2	138	2	17640964
Pubmed	Complementary functions of the flippase ATP8B1 and the floppase ABCB4 in maintaining canalicular membrane integrity.	ATP8B1 ABCB4	1.56e-05	2	138	2	21820390
Pubmed	The middle X residue influences cotranslational N-glycosylation consensus site skipping.	STT3A STT3B	1.56e-05	2	138	2	25029371
Pubmed	Proteome and Glycoproteome Analyses Reveal the Protein N-Linked Glycosylation Specificity of STT3A and STT3B.	STT3A STT3B	1.56e-05	2	138	2	36139350
Pubmed	Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta.	HTR1B HTR1D	1.56e-05	2	138	2	1565658
Pubmed	Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM model.	CCR1 CCR5	1.56e-05	2	138	2	17086356
Pubmed	Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor.	XCR1 CCR1	1.56e-05	2	138	2	7683036
Pubmed	Reduced CC chemokine receptor (CCR) 1 and CCR5 surface expression on peripheral blood T lymphocytes from patients with chronic hepatitis C infection.	CCR1 CCR5	1.56e-05	2	138	2	12085329
Pubmed	Role of Rho family GTPases in CCR1- and CCR5-induced actin reorganization in macrophages.	CCR1 CCR5	1.56e-05	2	138	2	15882964
Pubmed	Mammalian STT3A/B oligosaccharyltransferases segregate N-glycosylation at the translocon from lipid-linked oligosaccharide hydrolysis.	STT3A STT3B	1.56e-05	2	138	2	30181269
Pubmed	RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs.	DHX36 DHX9	1.56e-05	2	138	2	30591072
Pubmed	Combined blockade of the chemokine receptors CCR1 and CCR5 attenuates chronic rejection.	CCR1 CCR5	1.56e-05	2	138	2	14757698
Pubmed	Localization-Specific Expression of CCR1 and CCR5 by Mast Cell Progenitors.	CCR1 CCR5	1.56e-05	2	138	2	32174921
Pubmed	CCR1 and CCR5 promote hepatic fibrosis in mice.	CCR1 CCR5	1.56e-05	2	138	2	19603542
Pubmed	SMARCA4 (BRG1) activates ABCC3 transcription to promote hepatocellular carcinogenesis.	ABCC3 SMARCA4	1.56e-05	2	138	2	38642845
Pubmed	Tumor cell apoptosis induces tumor-specific immunity in a CC chemokine receptor 1- and 5-dependent manner in mice.	CCR1 CCR5	1.56e-05	2	138	2	18644849
Pubmed	CCR5Delta32 polymorphism effects on CCR5 expression, patterns of immunopathology and disease course in multiple sclerosis.	CCR1 CCR5	1.56e-05	2	138	2	16182378
Pubmed	Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.	TAS2R45 TAS2R43 TAS2R50	1.70e-05	13	138	3	15938754
Pubmed	Defining the membrane proteome of NK cells.	ZMPSTE24 PSEN2 MED16 ARFGEF2 RNF213 CERS6 STT3A STT3B DHX9 LRP8 CSE1L CLTC NUP133 SMARCA4 SLC37A4 SLC27A4	1.70e-05	1168	138	16	19946888
Pubmed	Pediatric Genetic Cholestatic Liver Disease Overview	ATP8B1 ABCB4 HSD3B7	2.15e-05	14	138	3	36108118
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	CLN8 SPG7 WFS1 CERS6 CHRM2 CHRM5 TMEM62 ADRA1A CCR1 CCR5 SLC37A4 PIGM	2.34e-05	697	138	12	28298427
Pubmed	EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired.	WFS1 TSC2 STT3A STT3B CLTC ALDH3A2	3.13e-05	150	138	6	32423001
Pubmed	Heterozygous mutations of ATP8B1, ABCB11 and ABCB4 cause mild forms of Progressive Familial Intrahepatic Cholestasis in a pediatric cohort.	ATP8B1 ABCB4	4.68e-05	3	138	2	34942279
Pubmed	Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells.	DHX36 DHX9	4.68e-05	3	138	2	20696886
Pubmed	Expression of serotonin receptors in mouse oocytes and preimplantation embryos.	HTR1B HTR1D	4.68e-05	3	138	2	12678665
Pubmed	STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion.	STT3A STT3B	4.68e-05	3	138	2	29765039
Pubmed	Clinical phenotype of adult-onset liver disease in patients with variants in ABCB4, ABCB11, and ATP8B1.	ATP8B1 ABCB4	4.68e-05	3	138	2	35894240
Pubmed	Elucidation of the CCR1- and CCR5-binding modes of MIP-1α by application of an NMR spectra reconstruction method to the transferred cross-saturation experiments.	CCR1 CCR5	4.68e-05	3	138	2	26472202
Pubmed	Chemokine receptors Ccr1, Ccr2, and Ccr5 mediate neutrophil migration to postischemic tissue.	CCR1 CCR5	4.68e-05	3	138	2	16275892
Pubmed	CCR2+ and CCR5+ CD8+ T cells increase during viral infection and migrate to sites of infection.	CCR1 CCR5	4.68e-05	3	138	2	10940868
Pubmed	Significance of N-terminal proteolysis of CCL14a to activity on the chemokine receptors CCR1 and CCR5 and the human cytomegalovirus-encoded chemokine receptor US28.	CCR1 CCR5	4.68e-05	3	138	2	19553544
Pubmed	Muscarinic cholinergic receptor (M2) plays a crucial role in the development of myopia in mice.	CHRM2 CHRM5	4.68e-05	3	138	2	23649821
Pubmed	Cotranslational and posttranslational N-glycosylation of polypeptides by distinct mammalian OST isoforms.	STT3A STT3B	4.68e-05	3	138	2	19167329
Pubmed	Presynaptic α2δ subunits are key organizers of glutamatergic synapses.	CACNA2D1 CACNA2D2	4.68e-05	3	138	2	33782113
Pubmed	Molecular and functional interaction between GPR18 and cannabinoid CB2 G-protein-coupled receptors. Relevance in neurodegenerative diseases.	GPR18 CNR2	4.68e-05	3	138	2	29870711
Pubmed	The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity.	CCR1 CCR5	4.68e-05	3	138	2	11116158
Pubmed	Targeted ablation of Abcc1 or Abcc3 in Abcc6(-/-) mice does not modify the ectopic mineralization process.	ABCC3 ABCC6	4.68e-05	3	138	2	17845218
Pubmed	Hepatic cytochrome P450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt-induced cholestasis.	ATP8B1 ABCB4	4.68e-05	3	138	2	25068656
Pubmed	CCR5, GPR15, and CXCR6 are major coreceptors of human immunodeficiency virus type 2 variants isolated from individuals with and without plasma viremia.	CXCR6 CCR5	4.68e-05	3	138	2	15650194
Pubmed	The alpha2delta subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function.	CACNA2D1 CACNA2D2	4.68e-05	3	138	2	20080692
Pubmed	CC chemokine ligand 3 and receptors 1 and 5 gene expression in recurrent aphthous stomatitis.	CCR1 CCR5	4.68e-05	3	138	2	22727097
Pubmed	Familial migraine with aura: association study with 5-HT1B/1D, 5-HT2C, and hSERT polymorphisms.	HTR1B HTR1D	4.68e-05	3	138	2	15109354
Pubmed	CCL5, CCR1 and CCR5 in murine glioblastoma: immune cell infiltration and survival rates are not dependent on individual expression of either CCR1 or CCR5.	CCR1 CCR5	4.68e-05	3	138	2	22425022
Pubmed	Sequencing of FIC1, BSEP and MDR3 in a large cohort of patients with cholestasis revealed a high number of different genetic variants.	ATP8B1 ABCB4	4.68e-05	3	138	2	28733223
Pubmed	DHPLC screening for mutations in progressive familial intrahepatic cholestasis patients.	ATP8B1 ABCB4	4.68e-05	3	138	2	20414253
Pubmed	Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy.	CXCR6 CCR5	4.68e-05	3	138	2	16470129
Pubmed	ATP8B1, ABCB11, and ABCB4 Genes Defects: Novel Mutations Associated with Cholestasis with Different Phenotypes and Outcomes.	ATP8B1 ABCB4	4.68e-05	3	138	2	33915153
Pubmed	Ccr5 but not Ccr1 deficiency reduces development of diet-induced atherosclerosis in mice.	CCR1 CCR5	4.68e-05	3	138	2	17138939
Pubmed	Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia.	CNIH2 CNIH3	4.68e-05	3	138	2	23103966
Pubmed	Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis.	CHRM2 ZP4 ECE2	6.63e-05	20	138	3	19626040
Pubmed	Use of (alternative) coreceptors for HIV entry.	CXCR6 CCR1 CCR5	7.71e-05	21	138	3	22842622
Pubmed	A novel family of mammalian taste receptors.	TAS2R45 TAS2R43 TAS2R50	7.71e-05	21	138	3	10761934
Pubmed	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.	TAS2R45 TAS2R43 TAS2R50	8.91e-05	22	138	3	12734386
Pubmed	Ultrasonic vocalizations induced by sex and amphetamine in M2, M4, M5 muscarinic and D2 dopamine receptor knockout mice.	CHRM2 CHRM5	9.33e-05	4	138	2	18382674
Interaction	CANX interactions	POMT2 GABRG2 ABCC3 TCTN3 CACNA2D1 ZMPSTE24 CACNA2D2 WFS1 NDST2 CERS6 DCT STT3A STT3B TG HSD3B7 TMTC3 CLTC EDEM2 ATXN3 NUP133 SELENOI ALDH3A2 ZRANB1 NUP160 CNR2 RNF26	8.08e-08	1261	128	26	int:CANX
Interaction	CCL4 interactions	SLC18A1 CCR1 CCR5 GPRC5D CNR2	1.68e-06	32	128	5	int:CCL4
Interaction	UNC93B1 interactions	TCTN3 HTR1B XPO4 RNF213 GPR101 STT3A STT3B CSE1L NUP133 GPRC5D TM4SF18 ALDH3A2 SLC27A4	2.60e-06	417	128	13	int:UNC93B1
Interaction	CRELD1 interactions	POMT2 ABCC3 SPG7 CERS6 TMTC3 ZNF408 PIGW ALG3	9.69e-06	163	128	8	int:CRELD1
Cytoband	3p21.3	XCR1 CACNA2D2 ZMYND10 SLC22A14	3.04e-05	59	137	4	3p21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr3p21	XCR1 CACNA2D2 MST1 ZMYND10 CXCR6 CCR1 CCR5	4.91e-05	316	137	7	chr3p21
Cytoband	3p21	MST1 CXCR6 CCR1	1.33e-04	33	137	3	3p21
Cytoband	13q32	GPR18 DCT	6.75e-04	13	137	2	13q32
Cytoband	2q24.3	CERS6 SLC38A11	1.03e-03	16	137	2	2q24.3
GeneFamily	Solute carriers	SLC25A14 SLC44A4 SLC5A2 SLC6A9 SLC9C1 SLC25A43 SLC50A1 SLC18A1 SLC22A14 SLC35G3 SLC38A11 SLC45A1 SLC37A4 SLC27A4 SLC22A31	8.81e-09	395	105	15	752
GeneFamily	5-hydroxytryptamine receptors, G protein-coupled	HTR1B HTR1D HTR1E HTR1F	7.38e-07	13	105	4	170
GeneFamily	Dolichyl D-mannosyl phosphate dependent mannosyltransferases\|Phosphatidylinositol glycan anchor biosynthesis	POMT2 ALG3 PIGM	1.56e-05	9	105	3	430
GeneFamily	STT3 oligosaccharyltransferase catalytic subunits\|Oligosaccharyltransferase complex subunits	STT3A STT3B	3.34e-05	2	105	2	444
GeneFamily	G protein-coupled receptors, Class A orphans	GPR18 MRGPRE GPR84 GPR101 MRGPRG	9.05e-05	78	105	5	262
GeneFamily	Cholinergic receptors muscarinic	CHRM2 CHRM5	3.30e-04	5	105	2	180
GeneFamily	Exportins	XPO4 CSE1L	6.88e-04	7	105	2	547
GeneFamily	G protein-coupled receptors, Class C orphans	GPR158 GPRC5D	6.88e-04	7	105	2	285
GeneFamily	CD molecules\|C-C motif chemokine receptors	CCR1 CCR5	1.46e-03	10	105	2	1091
GeneFamily	Taste 2 receptors	TAS2R45 TAS2R43 TAS2R50	1.49e-03	39	105	3	1162
GeneFamily	Oligosaccharyltransferase complex subunits	STT3A STT3B	2.12e-03	12	105	2	445
GeneFamily	ATP binding cassette subfamily C	ABCC3 ABCC6	2.50e-03	13	105	2	807
GeneFamily	DEAH-box helicases	DHX36 DHX9	3.80e-03	16	105	2	500
GeneFamily	Glycosyl transferases group 1 domain containing\|Phosphatidylinositol glycan anchor biosynthesis	PIGW PIGM	6.53e-03	21	105	2	680
GeneFamily	Calcium voltage-gated channel subunits	CACNA2D1 CACNA2D2	9.91e-03	26	105	2	253
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPNS2 CNIH2 PRSS22 SLC44A4 SLC6A9 SV2C STRA6	7.77e-07	164	137	7	c5bfae7e9497185548c243d6f9ebadbcef48ba7f
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPNS2 CNIH2 PRSS22 SLC44A4 SLC6A9 SV2C STRA6	7.77e-07	164	137	7	76b0ac220b7ca22fbea28a507f01f96ae9f53932
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPNS2 CNIH2 PRSS22 SLC44A4 SLC6A9 SV2C STRA6	7.77e-07	164	137	7	911081739174ec68bc0893c804e4276b206bea7d
ToppCell	droplet-Tongue-nan-24m-Myeloid-basal_cell\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR18 RFTN1 CXCR6 CD101 SV2C CCR1 CCR5	1.34e-06	178	137	7	9423e209de94d26e96117581c95dc069850225d3
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG2 CACNA2D1 BRINP3 HTR1F RFTN1 HRH2 SLC38A11	2.00e-06	189	137	7	c3df0e3c50af8f1cfb4d790e668bd7f42b276992
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Dendritic_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	OGFRL1 XCR1 NDST2 GPR84 CERS6 ABCB4 HRH2	2.64e-06	197	137	7	e0fc098bfb5a8b7824ae339f3adda30f78360d0b
ToppCell	severe-Plasmablast\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	COL4A4 SPAG4 WFS1 STT3A SLC6A9 EDEM2 ALG3	2.73e-06	198	137	7	0b1620ad4352ee5d599a72931aaceab4ca407498
ToppCell	remission-unassigned\|World / disease stage, cell group and cell class	XCR1 GPR18 SLC44A4 CXCR6 SLC38A11 HPS5	8.60e-06	155	137	6	d81bec894381e3e2d6249a567e8108b8423e5c54
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCC3 XPO4 PLA2G15 CLTC CCR1 CCR5	9.94e-06	159	137	6	c0e55f25271f788c08fa4b95186501fc27b2ec39
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	POMT2 CUL2 PLIN2 HSD3B7 SLC25A43 CD101	1.61e-05	173	137	6	b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCC3 GPR84 PLA2G15 CLTC CCR1 CCR5	1.77e-05	176	137	6	adb679e69c0c17f0caee4c141bac55d03c963012
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	POMT2 PLIN2 HSD3B7 SLC25A43 CXCR6 CD101	1.77e-05	176	137	6	437cfc5e06416bb0fc76d1f9dc106f74e279e880
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 ATP8B1 ABCC6 ABCB4 MST1 RNF103	2.20e-05	183	137	6	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	CF-Lymphoid-B_cell\|CF / Disease state, Lineage and Cell class	COL4A4 TCTN3 IFNLR1 WDR43 RFTN1 CNR2	2.72e-05	190	137	6	374d8fd63c733178acab07682ed1519693efab45
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL4A4 SPAG4 WFS1 STT3A EDEM2 GPRC5D	2.72e-05	190	137	6	84eb7761f537d270673909a71d4f122e826769d5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA2D1 OVOS2 FREM1 ADRA1A SV2C ECE2	2.80e-05	191	137	6	fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCell	Severe_COVID-19-Epithelial-transitional_Epi\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ABCA13 SPNS2 PRSS22 SLC44A4 ZMYND10 NME5	3.33e-05	197	137	6	5ad3cd4c77016e862041baac3076f8cc0f75c417
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-NK_CD56bright\|ICU-SEP / Disease, condition lineage and cell class	PSEN2 MST1 SLC25A43 TLE1 RTN4RL2 CNR2	3.33e-05	197	137	6	c187e3fc2160b0165eb039cf09a6e621016068b7
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CACNA2D1 BRINP3 SLC5A2 ADRA1A GPR158 SLC22A14	3.33e-05	197	137	6	b8dc192fc98428bbb701cc2ea57fc8ad93397785
ToppCell	control-B_intermediate\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	COL4A4 GPR18 ABCB4 TLE1 SLC38A11 CNR2	3.43e-05	198	137	6	e24345c8cec8c21f7b5163b7326ba8f83a587ce3
ToppCell	severe-Plasmablast\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	COL4A4 SPAG4 WFS1 STT3A SLC6A9 EDEM2	3.53e-05	199	137	6	6ee4c2e6049860071169366b7e662d5c1a3cc54b
ToppCell	distal-Hematologic-Myeloid_Dendritic_Type_1-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	OGFRL1 XCR1 GPR84 ABCB4 RFTN1 SLC22A14	3.53e-05	199	137	6	78e70852acda95d2c770cdd539a46b291f929a78
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	OVOS2 FREM1 ADRA1A ZFHX4 SV2C ECE2	3.63e-05	200	137	6	d0167f96314be78b6d867bbcc6e4396071d931b8
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-dn_T\|Int-URO / Disease, condition lineage and cell class	GPR18 SLC25A14 PLA2G15 SLC25A43 CXCR6 CCR5	3.63e-05	200	137	6	020439d9e70fff7246650ab0e9105236688c3ec3
ToppCell	mild-B_intermediate\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	COL4A4 IFNLR1 ABCB4 TLE1 SLC38A11 CNR2	3.63e-05	200	137	6	8e3132a1fe3708f725c5c4077878fb87bbea3678
ToppCell	LPS_only-Hematopoietic_Myeloid-Granulocytic_cells-Mast-cells\|LPS_only / Treatment groups by lineage, cell group, cell type	MYADML2 NDST2 PLIN2 GDPD5 SLC25A43 SLC38A11	3.63e-05	200	137	6	afbbfe0b8e66df36c244935182cb26feeb31a085
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GPR101 CHRM5 CNIH3 TBATA ZFHX4	5.13e-05	130	137	5	c70fb77324916d220d842a575558a8245c276599
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3\|Hippocampus / BrainAtlas - Mouse McCarroll V32	HTR1B HTR1F PRSS22 PKD1L2 GDPD5	6.82e-05	138	137	5	b63e26afafbd2cdeed9c9451e6f530ab6295504c
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CHRM5 CNIH3 TBATA ZFHX4 RTN4RL2	8.34e-05	144	137	5	e2a2f260f5ebaaef46248d199c407a15ce9d024a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 ABCA13 PRSS22 ZFHX4 SLC38A11	8.61e-05	145	137	5	8da10bc6611976e1ec85e09f04a2dc5bf6555c9e
ToppCell	E16.5-samps-Myeloid-Macrophage\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ABCC3 TG SSH3 CCR1 CNR2	9.48e-05	148	137	5	cd5f697d8c2f272be1f3f52a05446749278431c5
ToppCell	E16.5-samps-Myeloid-Macrophage-CD163+_Macrophage\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ABCC3 TG SSH3 CCR1 CNR2	9.48e-05	148	137	5	56e146980a71b5ca655118ae13310c5949220d4a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GABRG2 COL4A4 ABCA13 GPR84 SLC38A11	1.04e-04	151	137	5	16fc903fc71e25717b9908416f0bcd29c0a65a61
ToppCell	remission-unassigned\|remission / disease stage, cell group and cell class	XCR1 SLC44A4 CXCR6 SLC38A11 HPS5	1.14e-04	154	137	5	4130769829b838cc8a075c87ff6c187f0f507f8b
ToppCell	368C-Fibroblasts-Fibroblast-H\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CACNA2D2 TSC2 CNIH3 GTF3C2 RNF26	1.14e-04	154	137	5	f29316d4b4dcdb23bd427d78068e65a9802f7f07
ToppCell	368C-Fibroblasts-Fibroblast-H-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CACNA2D2 TSC2 CNIH3 GTF3C2 RNF26	1.14e-04	154	137	5	66065c0763c83d98084ca6969694c3af37e43274
ToppCell	Striatum-Hematopoietic\|Striatum / BrainAtlas - Mouse McCarroll V32	ABCC3 GPR84 CD101 CCR1 CCR5	1.18e-04	155	137	5	12301d823338bf829475905c66c5f08f7159d29f
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	BRINP3 CYP39A1 CNIH3 GDPD5 GPR158	1.29e-04	158	137	5	c8af8964a140acb2987e3b4906d72c546108d229
ToppCell	Frontal_cortex-Hematopoietic-MICROGLIA\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ABCC3 GPR84 CD101 CCR5 CNR2	1.33e-04	159	137	5	41d2c1e71f6983156f8cc8ec5f69e025e5700f46
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP39A1 ABCB4 SLC6A9 ALDH3A2 SLC37A4	1.37e-04	160	137	5	c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-EECs\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 BRINP3 CNIH2 SLC18A1 SV2C	1.45e-04	162	137	5	478cf560ef33c5c324142c76417447d4a571a2c9
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	BRINP3 CYP39A1 CHRM2 CNIH3 GPR158	1.49e-04	163	137	5	1e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	BRINP3 CYP39A1 CHRM2 CNIH3 GPR158	1.49e-04	163	137	5	431221a41d396b09170476179590eaf8a55266d8
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	COL4A4 TCTN3 GPR18 CCR5 RNF26	1.53e-04	164	137	5	d8ecb3de6e34f5f574449e3d2f26fa0b2b7e84e8
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRG2 GPR101 CHRM2 CHRM5 CNIH3	1.62e-04	166	137	5	548d0d6c0ffd564036ddba78620734220ebb73d7
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRG2 GPR101 CHRM2 CHRM5 CNIH3	1.62e-04	166	137	5	80e164a89d22098cabe4a99a78283ba69ea0561e
ToppCell	moderate-Myeloid-Mast_cell\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CACNA2D1 CACNA2D2 TGFB1I1 PIEZO2 SLC38A11	1.62e-04	166	137	5	c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Ndst4_(Subiculum)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GPR101 CHRM5 TBATA HRH2	1.64e-04	89	137	4	497771687b48c7e0fa87e31962feaafd8f248b98
ToppCell	facs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A2 ABCB4 MST1 SLC6A9 GPR158	1.72e-04	168	137	5	08fe8fa43c343c03f9a2f0b982192fde04a7c027
ToppCell	facs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A2 ABCB4 MST1 SLC6A9 GPR158	1.72e-04	168	137	5	d4053b2fffb19e0376b8ceb92e87ec4447d96a3e
ToppCell	TCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Spindle_Cell-1\|TCGA-Uvea / Sample_Type by Project: Shred V9	MED16 CNIH2 GDPD5 SSH3 RTN4RL2	1.72e-04	168	137	5	b427746929bb40e3d1b5f1c40d302b792d6b32a5
ToppCell	390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|390C / Donor, Lineage, Cell class and subclass (all cells)	ABCC3 GPR84 PLA2G15 HRH2 CCR1	1.76e-04	169	137	5	2c851b2703c7b8b656026f996f5fc027e4a79b36
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCC3 BRINP3 HTR1F CHRM2 SLC38A11	1.81e-04	170	137	5	49fc45d8a5c3ad89d1649fa46d7a285891379392
ToppCell	(7)_MNP-(7)_DC_activated\|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)	PSEN2 OVOS2 CERS6 RFTN1 PIEZO2	1.81e-04	170	137	5	4ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCC3 PRSS22 ATP8B1 SLC44A4 TAS2R50	1.86e-04	171	137	5	3ef44a5e3e8f81424f1e9aa302860b6688a549b8
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCC3 PRSS22 ATP8B1 SLC44A4 TAS2R50	1.86e-04	171	137	5	3a2fefcb62e9d47ae6b3a946c45d3f2dd32c576c
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HTR1F ATP8B1 SLC6A9 SLC9C1 HRH2	1.86e-04	171	137	5	285533ca2a6a411773313166bee35542f34d1a3c
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RNF213 PLA2G15 PLIN2 HSD3B7 SLC22A14	1.92e-04	172	137	5	c8ea80042faf923b08ff03d73100533d521d73ef
ToppCell	mild_COVID-19_(asymptomatic)-cDC\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	TCTN3 XCR1 MPV17L2 SV2C STRA6	1.97e-04	173	137	5	71dc0051c87b84e3cf13cde8858166f2a474b5dc
ToppCell	wk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	HTR1E CHRM2 CD101 SLC45A1 STRA6	1.97e-04	173	137	5	b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCell	390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ABCC3 LRRC4 PLA2G15 HRH2 CCR1	1.97e-04	173	137	5	1f725ff16e28636b20ef26f3fa9be8b47c89378d
ToppCell	Endothelial-B-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	OVOS2 CYP39A1 PIEZO2 ZFHX4 TM4SF18	1.97e-04	173	137	5	a81992965137195d20fc498f750975303961a828
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	GPR18 CACNA2D2 ATP8B1 SLC44A4 ABCC6	2.02e-04	174	137	5	110369f6b78de34a6d934b5b47cecd023347bc80
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 SLC18A1 SV2C SLC38A11 SLC45A1	2.02e-04	174	137	5	a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPNS2 SLC44A4 CYP39A1 SLC6A9 GDPD5	2.08e-04	175	137	5	3f1b2e23fec953148fb0711e523c463adb07dca4
ToppCell	AT1-AT2_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	COL4A4 CACNA2D2 WFS1 SPNS2 TAS2R43	2.08e-04	175	137	5	bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SPAG4 WFS1 SLC6A9 EDEM2 GPRC5D	2.08e-04	175	137	5	3b5346fba617292de71963b6175e85a4f182fe30
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CACNA2D1 WFS1 CNIH3 ZMYND10 RTN4RL2	2.08e-04	175	137	5	ff0789f5913c9f3c49159e40b1ec3d2ff175ec9f
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCC3 PLA2G15 CLTC CCR1 CCR5	2.08e-04	175	137	5	53e6f1f8dd482dfa2539e068dacefbb6e08443bc
ToppCell	droplet-Pancreas-PANCREAS-30m-Hematologic-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR18 CXCR6 CD101 CCR1 CCR5	2.08e-04	175	137	5	ca2eabf03b70353e7eb15b6f622b2f9223a99e18
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CACNA2D1 WFS1 CNIH3 ZMYND10 RTN4RL2	2.08e-04	175	137	5	21f8f11a8b874d4f7c47931010a2535f2a5a3373
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 SLC9C1 SLC18A1 SV2C SLC38A11	2.13e-04	176	137	5	2e1003dc373b14d27f0464d980453fdcfc1005f0
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_THTPA\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCC3 HTR1B CHRM2 FREM1 GDPD5	2.13e-04	176	137	5	e788c7e0b2bfde31fddbf9e04d07140f8b964857
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCC3 GPR84 PLA2G15 CLTC CCR1	2.19e-04	177	137	5	ab92ffc9624850a50c88e6b8f3a517ff2251ff15
ToppCell	facs-Marrow-B-cells-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYADML2 POGK TG SLC25A43 EDEM2	2.19e-04	177	137	5	35d42b07d9c31528bf59199e361bb8a3bfbe3b75
ToppCell	NS-critical-d_07-13-Lymphoid-B_cell\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	COL4A4 GPR18 ABCB4 RFTN1 CNR2	2.19e-04	177	137	5	d4db058c09012ec9fbde61277a9f86d9956de8fc
ToppCell	cellseq2-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	HTR1F SLC25A14 CNIH3 RFTN1 SLC38A11	2.19e-04	177	137	5	68263456a3c93cd195b321b309ff59e156d732fe
ToppCell	NS-moderate-d_16-33-Lymphoid-B_cell\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	COL4A4 GPR18 ABCB4 RFTN1 CNR2	2.19e-04	177	137	5	320fd77c7c98e9305dcc34a168ec9d674539ed65
ToppCell	cellseq2-Mesenchymal-Myocytic-Myocytic_1\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	HTR1F SLC25A14 CNIH3 RFTN1 SLC38A11	2.19e-04	177	137	5	e415e448c37adc102d766235e9953dec32c021f1
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA2D1 CHRM2 SLC6A9 RFTN1 GPR158	2.25e-04	178	137	5	185b44700f06ec58b3c09c80520502166c965fd6
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 ATP8B1 TGFB1I1 ZMYND10 SLC38A11	2.25e-04	178	137	5	7467e5ab2fcb39cc4a2c7dd69722c91def3b6aea
ToppCell	normal-na-Lymphocytic_B-plasmablast-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	WFS1 CHRM5 STT3A SLC6A9 GPRC5D	2.25e-04	178	137	5	40a280c1e35963dd45d1809a3e85b568344dd1f5
ToppCell	normal-na-Lymphocytic_B-plasmablast\|normal / PBMC cell types (v2) per disease, treatment status, and sex	WFS1 CHRM5 STT3A SLC6A9 GPRC5D	2.25e-04	178	137	5	4fe87c713770173336177e3488f7b4a3be54f71b
ToppCell	Posterior_cortex-Hematopoietic\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ABCC3 GPR84 CCR1 CCR5 CNR2	2.25e-04	178	137	5	ea9e4f461dda34c0ebc707d7dbefc7a49ce5bb55
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 RFTN1 PIEZO2 ZFHX4 SLC22A31	2.25e-04	178	137	5	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 CNIH2 SLC18A1 SV2C SLC38A11	2.30e-04	179	137	5	8ce5000088b727783a0619baa16a2cd036d21f54
ToppCell	BAL-Severe-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL4A4 TSC2 ATP8B1 IFNLR1 ABCB4	2.36e-04	180	137	5	9f4bbaf6435c23e3e552ae22be8ea7884314192d
ToppCell	cellseq-Immune-Lymphocytic_B-Lymphocytic_B\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SPAG4 GPR18 ABCB4 GPRC5D CNR2	2.36e-04	180	137	5	cd04d7bf92986a5b8a0193c9b92ec47da3929bac
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRG2 OGFRL1 MYADML2 CNIH2 GPR158	2.36e-04	180	137	5	d76349ecef7c5878bf215e946f032264161eb61b
ToppCell	BAL-Severe-Lymphocyte-B-B_cell-B_cell\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL4A4 TSC2 ATP8B1 IFNLR1 ABCB4	2.36e-04	180	137	5	b465f2f8b0e9a2034a4f1272bb00c77439164dbf
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PSEN2 PLA2G15 PLIN2 LRP8 CCR1	2.36e-04	180	137	5	cc31d2cd06161300b91b17a67bb432b75f0d719b
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	POMT2 ABCA13 SLC44A4 LRRC4 ZMYND10	2.36e-04	180	137	5	1f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell	BAL-Severe-Lymphocyte-B-B_cell\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL4A4 TSC2 ATP8B1 IFNLR1 ABCB4	2.36e-04	180	137	5	c3c72531af5b9f7a7416727fe609dab5180e03b6
ToppCell	cellseq-Immune-Lymphocytic_B\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SPAG4 GPR18 ABCB4 GPRC5D CNR2	2.36e-04	180	137	5	663a800ab70e7ab7d13183417f9c1ed36907aa5e
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCC3 PLA2G15 CLTC CCR1 CCR5	2.36e-04	180	137	5	a600bc705993d3a010550a25d3b54358946f061f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_GGT8P\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A4 ABCC6 FREM1 ADRA1A SV2C	2.43e-04	181	137	5	9842537f9a607d8557c43790008d175edab1f32c
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BRINP3 HTR1E HTR1F GRIK4 RTN4RL2	2.43e-04	181	137	5	9de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCell	Endothelial-B-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	WFS1 OVOS2 PIEZO2 TM4SF18 RTN4RL2	2.43e-04	181	137	5	4fe0215d08f03d4e24749d70fce01b7aa22906fd
ToppCell	T_cells-Resident_memory_CD8+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	CNIH2 CXCR6 CD101 CCR1 CCR5	2.49e-04	182	137	5	111d434b89902ec11fb07f41b8ee1a98f3991b61
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PSEN2 PLA2G15 PLIN2 LRP8 CCR1	2.49e-04	182	137	5	94d061b7b5ebbfc564c644bc8b2d52341927145d
Computational	Genes in the cancer module 571.	COL4A4 GPR18 ATXN3	1.63e-04	15	79	3	MODULE_571
Computational	Neighborhood of MAGEA9	COL4A4 CACNA2D1 BRINP3 HTR1B GPR18 HTR1E ARFGEF2 ATP8B1 ADRA1A SLC18A1 ATXN3	2.49e-04	423	79	11	MORF_MAGEA9
Computational	Neighborhood of IL16	CACNA2D1 BRINP3 GPR18 HTR1E ARFGEF2 ATP8B1 SLC18A1 ATXN3	3.56e-04	239	79	8	MORF_IL16
Computational	Neighborhood of RAD51L3	CACNA2D1 BRINP3 HTR1B GPR18 HTR1E ARFGEF2 ATP8B1 ADRA1A SLC18A1 ATXN3	5.11e-04	387	79	10	MORF_RAD51L3
Computational	Neighborhood of ATF2	CACNA2D1 BRINP3 GPR18 HTR1E ARFGEF2 ATP8B1 ADRA1A TLE1 ATXN3	6.75e-04	330	79	9	MORF_ATF2
Drug	thioridazine	CACNA2D1 HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 ADRA1A ZMYND10	1.14e-09	79	137	9	CID000005452
Drug	alpha-methylserotonin	HTR1B HTR1D HTR1E HTR1F CHRM2 ADRA1A	2.93e-09	22	137	6	CID000115292
Drug	NSC95090	CACNA2D1 HTR1B HTR1D HTR1E HTR1F CHRM2 ADRA1A	3.87e-09	40	137	7	CID000003251
Drug	Olanzapine	HTR1B HTR1D HTR1E CHRM2 CHRM5 ADRA1A	6.85e-09	25	137	6	DB00334
Drug	Ziprasidone	HTR1B HTR1D HTR1E CHRM2 CHRM5 ADRA1A	6.85e-09	25	137	6	DB00246
Drug	Aripiprazole	HTR1B HTR1D HTR1E CHRM2 CHRM5 ADRA1A	6.85e-09	25	137	6	DB01238
Drug	Clozapine	HTR1B HTR1D HTR1E CHRM2 CHRM5 ADRA1A	8.87e-09	26	137	6	DB00363
Drug	Quetiapine	HTR1B HTR1D HTR1E CHRM2 CHRM5 ADRA1A	8.87e-09	26	137	6	DB01224
Drug	NSC196867	HTR1B HTR1D HTR1E HTR1F ADRA1A	9.08e-09	13	137	5	CID000003982
Drug	loxapine	HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 ADRA1A	1.08e-08	46	137	7	CID000003964
Drug	zotepine	HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 ADRA1A	1.70e-08	49	137	7	CID000005736
Drug	3-isoreserpine	ABCC3 CACNA2D1 HTR1B HTR1D HTR1F ABCA13 CHRM2 ABCC6 ABCB4 ADRA1A SLC18A1	2.17e-08	190	137	11	CID000005052
Drug	xanomeline	HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5	2.77e-08	31	137	6	CID000060809
Drug	mesoridazine	HTR1B HTR1F CHRM2 CHRM5 TG ADRA1A	4.12e-08	33	137	6	CID000004078
Drug	Eletriptan	HTR1B HTR1D HTR1E HTR1F	4.33e-08	7	137	4	DB00216
Drug	BRL 34778	HTR1B HTR1D HTR1F CHRM2	4.33e-08	7	137	4	CID000135770
Drug	quetiapine	HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 ADRA1A	5.04e-08	57	137	7	CID000005002
Drug	norfenfluramine	HTR1B HTR1D HTR1F CHRM2 CHRM5 ZMYND10	8.48e-08	37	137	6	CID000015897
Drug	secoverine	HTR1B HTR1D CHRM2 CHRM5	8.62e-08	8	137	4	CID000042470
Drug	fluphenazine	HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 ADRA1A ZMYND10	1.01e-07	94	137	8	CID000003372
Drug	Saphris	HTR1B HTR1D HTR1E CHRM2 CHRM5 ADRA1A	1.61e-07	41	137	6	CID000163091
Drug	amitriptyline	CACNA2D1 HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 ADRA1A ZMYND10	1.78e-07	140	137	9	CID000002160
Drug	Rizatriptan	HTR1B HTR1D HTR1F	2.13e-07	3	137	3	DB00953
Drug	AC1Q5UBL	GABRG2 CACNA2D1 HTR1B HTR1F GRIK4 CHRM2 STT3A ADRA1A SLC18A1	2.55e-07	146	137	9	CID000005466
Drug	CM 29-712	HTR1B HTR1D HTR1F ADRA1A	2.56e-07	10	137	4	CID000159842
Drug	LY344864	HTR1B HTR1D HTR1E HTR1F	2.56e-07	10	137	4	CID005311097
Drug	spiperone	CACNA2D1 HTR1B HTR1D HTR1E HTR1F CHRM2 ADRA1A ZMYND10	2.97e-07	108	137	8	CID000005265
Drug	chlorpromazine	CACNA2D1 HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 ADRA1A ZMYND10 CLTC	3.31e-07	197	137	10	CID000002726
Drug	pizotifen	CACNA2D1 HTR1B HTR1D HTR1E HTR1F	3.54e-07	25	137	5	CID000027400
Drug	cyclandelate	HTR1B HTR1D HTR1F STT3A	4.01e-07	11	137	4	CID000002893
Drug	dicyclomine	HTR1B HTR1D CHRM2 CHRM5	4.01e-07	11	137	4	CID000003042
Drug	alniditan	HTR1B HTR1D HTR1E HTR1F	4.01e-07	11	137	4	CID000066004
Drug	Ergot	CACNA2D1 HTR1B HTR1D HTR1E HTR1F ADRA1A	4.24e-07	48	137	6	CID000003250
Drug	1-(1-naphthyl)piperazine	HTR1B HTR1D HTR1E HTR1F ADRA1A	4.36e-07	26	137	5	CID000001342
Drug	T15550	HTR1B HTR1D CHRM2 CHRM5 ADRA1A	4.36e-07	26	137	5	CID000005454
Drug	sertindole	HTR1B HTR1D HTR1E HTR1F CHRM2 ADRA1A	5.44e-07	50	137	6	CID000060149
Drug	AQ-RA 741	HTR1B HTR1D CHRM2 CHRM5	5.98e-07	12	137	4	CID000129989
Drug	citalopram	HTR1B HTR1D HTR1F DCT CHRM2 DHX9 ADRA1A SLC18A1	6.67e-07	120	137	8	CID000002771
Drug	Zolmitriptan	HTR1B HTR1D HTR1F	8.49e-07	4	137	3	DB00315
Drug	Is 159	HTR1B HTR1D HTR1F	8.49e-07	4	137	3	CID000196859
Drug	Naratriptan	HTR1B HTR1D HTR1F	8.49e-07	4	137	3	DB00952
Drug	Sumatriptan	HTR1B HTR1D HTR1F	8.49e-07	4	137	3	DB00669
Drug	MDL 72832	HTR1B HTR1D HTR1F ADRA1A	8.60e-07	13	137	4	CID000182585
Drug	AC1L1G8Z	HTR1B HTR1D HTR1E HTR1F ADRA1A	9.26e-07	30	137	5	CID000003581
Drug	mianserin	HTR1B HTR1D HTR1E HTR1F CHRM2 ADRA1A ZMYND10	9.58e-07	87	137	7	CID000004184
Drug	idazoxan	CACNA2D1 HTR1B HTR1D HTR1E HTR1F CHRM2 ADRA1A	1.12e-06	89	137	7	CID000054459
Drug	L-694,247	HTR1B HTR1D HTR1E HTR1F	1.20e-06	14	137	4	CID000132059
Drug	Nicardipine	CACNA2D1 CHRM2 CHRM5 ADRA1A	1.20e-06	14	137	4	DB00622
Drug	ketanserin	CACNA2D1 HTR1B HTR1D HTR1E HTR1F CHRM2 ADRA1A SLC18A1	1.30e-06	131	137	8	CID000003822
Drug	dotarizine	CACNA2D1 HTR1B HTR1F ZMYND10	1.63e-06	15	137	4	CID000055285
Drug	urapidil	CACNA2D1 HTR1B HTR1D HTR1F ADRA1A	1.77e-06	34	137	5	CID000005639
Drug	Trelibet	HTR1B HTR1D HTR1F	2.11e-06	5	137	3	CID000065975
Drug	GR 127935	HTR1B HTR1D ADRA1A	2.11e-06	5	137	3	ctd:C090701
Drug	BEA 1654	HTR1B HTR1F ADRA1A	2.11e-06	5	137	3	CID000125354
Drug	4-amino-5-chloro-2-methoxybenzamide	HTR1B HTR1D HTR1F	2.11e-06	5	137	3	CID009834239
Drug	I 370	HTR1B HTR1D HTR1F	2.11e-06	5	137	3	CID000089576
Drug	centbutindole	HTR1B HTR1D HTR1F	2.11e-06	5	137	3	CID000068663
Drug	Methysergide	HTR1B ABCB4 ADRA1A	2.11e-06	5	137	3	ctd:D008784
Drug	CP-132,484	HTR1B HTR1D HTR1F	2.11e-06	5	137	3	CID000132564
Drug	AC1LCKBJ	HTR1B HTR1D HTR1F	2.11e-06	5	137	3	CID000601768
Drug	desipramine	HTR1B HTR1D HTR1F MED16 CHRM2 CHRM5 ADRA1A ZMYND10 SLC18A1	2.13e-06	188	137	9	CID000002995
Drug	L-DOPA methyl ester	HTR1B HTR1D DCT SLC18A1	2.16e-06	16	137	4	CID000023497
Drug	S-(-)-Lisuride	HTR1B HTR1D HTR1E HTR1F CHRM2 ADRA1A	2.62e-06	65	137	6	CID000003938
Drug	promazine	HTR1B HTR1F CHRM2 CHRM5 ADRA1A	2.74e-06	37	137	5	CID000004926
Drug	TFMPP	HTR1B HTR1D HTR1E HTR1F ZMYND10	2.74e-06	37	137	5	CID000004296
Drug	benzoctamine	HTR1B HTR1D HTR1E HTR1F	3.60e-06	18	137	4	CID000028425
Drug	tripitramine	HTR1B HTR1D CHRM2 CHRM5	3.60e-06	18	137	4	CID000132947
Drug	AC1NUW4G	HTR1B HTR1D HTR1F CHRM2 CHRM5	4.07e-06	40	137	5	CID005462134
Drug	pyrrolo(1,2-a)quinoxaline	HTR1B HTR1D HTR1F	4.21e-06	6	137	3	CID000067476
Drug	R 28935	HTR1B HTR1D HTR1F	4.21e-06	6	137	3	CID000093307
Drug	oriens	GABRG2 HTR1B HTR1D GRIK4 CHRM2 ADRA1A TLE1 CCR5	4.37e-06	154	137	8	CID000161645
Drug	EEDQ	HTR1B HTR1D HTR1E HTR1F CHRM2 ADRA1A	4.80e-06	72	137	6	CID000027833
Drug	haloperidol	GABRG2 HTR1B HTR1D HTR1E HTR1F GRIK4 CHRM2 CHRM5 ADRA1A ZMYND10 SLC18A1 CNR2	4.86e-06	394	137	12	CID000003559
Drug	nisoxetine	HTR1B HTR1D ADRA1A ZMYND10 SLC18A1	5.21e-06	42	137	5	CID000004500
Drug	Doxepin	CHRM2 CHRM5 ADRA1A HRH2	5.64e-06	20	137	4	DB01142
Drug	6-nitroquipazine	CLN8 HTR1B HTR1D HTR1F	5.64e-06	20	137	4	CID000005012
Drug	gamma-aminobutyric acid	GABRG2 CACNA2D1 HTR1B HTR1D SPG7 CACNA2D2 GRIK4 CHRM2 SLC6A9 ZMYND10 SLC18A1 ALDH3A2 CNR2	6.01e-06	474	137	13	CID000000119
Drug	SCH 23390	HTR1B HTR1D HTR1E HTR1F CHRM2 ADRA1A CNR2	6.62e-06	116	137	7	CID000005018
Drug	epicholesterol	HTR1B HTR1D HTR1E HTR1F ZMPSTE24 ATP8B1 CYP39A1 CHRM2 PLA2G15 PLIN2 LRP8 ABCB4 HSD3B7 CLTC SLC27A4	6.98e-06	636	137	15	CID000000304
Drug	methiothepin	HTR1B HTR1D HTR1E HTR1F CHRM2 ADRA1A	7.10e-06	77	137	6	CID000004106
Drug	NSC755875	CACNA2D1 HTR1B HTR1D HTR1F CHRM2 ADRA1A ZMYND10 SLC18A1	7.26e-06	165	137	8	CID000002215
Drug	adafenoxate	HTR1B HTR1D HTR1F	7.33e-06	7	137	3	CID000064517
Drug	LY334370	HTR1B HTR1D HTR1F	7.33e-06	7	137	3	CID005311258
Drug	L-689,660	HTR1B HTR1D CHRM2	7.33e-06	7	137	3	CID000132658
Drug	NSC186061	CACNA2D1 HTR1B HTR1D HTR1E HTR1F CHRM2 ADRA1A	7.41e-06	118	137	7	CID000004163
Drug	promethazine	CHRM2 CHRM5 ADRA1A TMTC3 RNF103	8.24e-06	46	137	5	CID000004927
Drug	oxymetazoline	HTR1B HTR1D HTR1E HTR1F CHRM2 ADRA1A	8.24e-06	79	137	6	CID000004636
Drug	zacopride	HTR1B HTR1D HTR1F ZMYND10	8.44e-06	22	137	4	CID000108182
Drug	mCPBG	HTR1B HTR1D HTR1F ZMYND10	8.44e-06	22	137	4	CID000001354
Drug	GR127935	HTR1B HTR1D HTR1E HTR1F	8.44e-06	22	137	4	CID000107780
Drug	buspirone	HTR1B HTR1D HTR1E HTR1F ADRA1A ZMYND10	8.87e-06	80	137	6	CID000002477
Drug	clomipramine	HTR1B HTR1D HTR1F CHRM2 ADRA1A SLC18A1	8.87e-06	80	137	6	CID000002801
Drug	fluoxetine	GABRG2 HTR1B HTR1D HTR1E HTR1F CHRM2 CHRM5 ADRA1A ZMYND10	9.18e-06	225	137	9	CID000003386
Drug	aganodine	HTR1B HTR1D ADRA1A CNR2	1.02e-05	23	137	4	CID000176878
Drug	AC1NDOB4	POMT2 PIGW ALG3 PIGM	1.02e-05	23	137	4	CID004629010
Drug	One-time	HTR1B HTR1D HTR1F GRIK4 CLTC	1.02e-05	48	137	5	CID000040813
Drug	Neomigran	CACNA2D1 HTR1B HTR1D HTR1F ADRA1A	1.02e-05	48	137	5	CID000003066
Drug	WAY-100635	HTR1B HTR1D HTR1F CHRM2 ADRA1A	1.13e-05	49	137	5	CID000005684
Drug	AC1L5AAF	HTR1B HTR1D HTR1F	1.17e-05	8	137	3	CID000173615
Drug	medifoxamine	HTR1B HTR1E HTR1F	1.17e-05	8	137	3	CID000036109
Disease	intrahepatic cholestasis (is_implicated_in)	ATP8B1 ABCB4 HSD3B7	3.57e-07	4	133	3	DOID:1852 (is_implicated_in)
Disease	generalized anxiety disorder (implicated_via_orthology)	HTR1B HTR1D HTR1E	4.93e-06	8	133	3	DOID:14320 (implicated_via_orthology)
Disease	Depressive disorder	HTR1B HTR1D WFS1 CHRM2 TG SLC18A1 TLE1 ATXN3 CNR2	6.90e-06	289	133	9	C0011581
Disease	Schizophrenia	GABRG2 HTR1F PSEN2 ABCA13 GRIK4 CHRM2 CHRM5 CNIH3 LRP8 SLC6A9 ADRA1A SLC18A1 EDEM2 CCR5 CNR2	1.12e-05	883	133	15	C0036341
Disease	congenital disorder of glycosylation Iw (implicated_via_orthology)	STT3A STT3B	2.02e-05	2	133	2	DOID:0080572 (implicated_via_orthology)
Disease	Progressive intrahepatic cholestasis (disorder)	ATP8B1 ABCB4	6.03e-05	3	133	2	C0268312
Disease	Progressive familial intrahepatic cholestasis type 3	ATP8B1 ABCB4	6.03e-05	3	133	2	cv:C1865643
Disease	restrictive dermopathy (implicated_via_orthology)	ZMPSTE24 SLC27A4	6.03e-05	3	133	2	DOID:0060762 (implicated_via_orthology)
Disease	Cholestasis, benign recurrent intrahepatic 1	ATP8B1 ABCB4	6.03e-05	3	133	2	C4551899
Disease	Cobblestone Lissencephaly	POMT2 TMTC3	6.03e-05	3	133	2	C0431376
Disease	Glycosylphosphatidylinositol deficiency	PIGW PIGM	6.03e-05	3	133	2	C1853205
Disease	Bipolar Disorder	HTR1B PSEN2 ABCA13 WFS1 GRIK4 CHRM2 ADRA1A SLC18A1 GPRC5D CNR2	6.37e-05	477	133	10	C0005586
Disease	Familial intrahepatic cholestasis of pregnancy	ATP8B1 ABCB4	1.20e-04	4	133	2	C3489728
Disease	Cholestasis, progressive familial intrahepatic 1	ATP8B1 ABCB4	1.20e-04	4	133	2	C4551898
Disease	anxiety disorder (implicated_via_orthology)	HTR1B TSC2 CNR2	1.29e-04	22	133	3	DOID:2030 (implicated_via_orthology)
Disease	Mental Depression	HTR1B WFS1 CHRM2 SLC18A1 TLE1 ATXN3 CNR2	1.60e-04	254	133	7	C0011570
Disease	Cocaine Abuse	GABRG2 HTR1B CHRM5 ADRA1A SMARCA4	2.82e-04	127	133	5	C0009171
Disease	Cholangitis, Sclerosing	ABCB4 MST1	2.99e-04	6	133	2	C0008313
Disease	Periventricular Nodular Heterotopia	ARFGEF2 TMTC3	4.17e-04	7	133	2	C1868720
Disease	Cocaine Dependence	GABRG2 HTR1B CHRM5 ADRA1A SMARCA4	4.28e-04	139	133	5	C0600427
Disease	Cholestasis of pregnancy	ATP8B1 ABCB4	5.55e-04	8	133	2	C0268318
Disease	Primary sclerosing cholangitis	ABCB4 MST1	5.55e-04	8	133	2	C0566602
Disease	Developmental delay (disorder)	CACNA2D2 STT3A STT3B	6.22e-04	37	133	3	C0424605
Disease	anterior uveitis (biomarker_via_orthology)	CCR1 CCR5	7.11e-04	9	133	2	DOID:1407 (biomarker_via_orthology)
Disease	Coronavirus infectious disease (implicated_via_orthology)	CCR1 CCR5	7.11e-04	9	133	2	DOID:0080599 (implicated_via_orthology)
Disease	Unipolar Depression	HTR1B GRIK4 LRP8 TG ADRA1A CNR2	1.17e-03	259	133	6	C0041696
Disease	Epilepsy	GABRG2 CACNA2D2 TSC2 CHRM2	1.52e-03	109	133	4	C0014544
Disease	phoneme awareness	ARFGEF2 CSE1L	1.77e-03	14	133	2	EFO_0021812
Disease	Cocaine-Related Disorders	GABRG2 HTR1B CHRM5 SMARCA4	1.97e-03	117	133	4	C0236736
Disease	response to carboplatin	IFNLR1 GPR158 NME5	2.30e-03	58	133	3	GO_0097328
Disease	copine-1 measurement	SPAG4 EDEM2	2.62e-03	17	133	2	EFO_0008102
Disease	Moyamoya Disease	RNF213 ABCC6	2.62e-03	17	133	2	C0026654
Disease	Disorder of eye	CLN8 TCTN3 WFS1 FREM1 STRA6	2.79e-03	212	133	5	C0015397
Disease	C-X-C motif chemokine 16 measurement	XCR1 CXCR6	2.94e-03	18	133	2	EFO_0010911
Disease	primary ciliary dyskinesia (implicated_via_orthology)	ZMYND10 NME5	3.28e-03	19	133	2	DOID:9562 (implicated_via_orthology)
Disease	sensorineural hearing loss (implicated_via_orthology)	SLC44A4 ZMYND10	3.28e-03	19	133	2	DOID:10003 (implicated_via_orthology)
Disease	glaucoma (is_marker_for)	RFTN1 CCR5	3.63e-03	20	133	2	DOID:1686 (is_marker_for)
Disease	energy expenditure measurement	CACNA2D1 GPR158	3.63e-03	20	133	2	EFO_0008005
Disease	lung cancer	ATP8B1 ZRANB1	4.00e-03	21	133	2	MONDO_0008903

Protein segments in the cluster

Peptide	Gene	Start	Entry
VLLLTLYTVLGPWFF	TMEM62	486	Q0P6H9
LDLPLQCYNWTLTLG	BRINP3	601	Q76B58
WLGYLNSLINPIIYT	HTR1B	356	P28222
WVISLLVSLPQIIYG	CXCR6	156	O00574
AAAWSLFQQLLYGLI	CACNA2D2	976	Q9NY47
FLAWLGYLNSLINPL	HTR1F	331	P30939
PYWLLVFLAALNALL	HSD3B7	291	Q9H2F3
LLVLGLIELSWNTYP	ALG3	386	Q92685
VFWLGYLNSCINPII	ADRA1A	311	P35348
PLFVQLILENIWSLY	EFL1	291	Q7Z2Z2
ILGALTVFYPSIALW	GPR18	96	Q14330
WLGYVNSLINPLLYT	HTR1E	331	P28566
LVWTPLLAAYSIGLQ	ARFGEF2	896	Q9Y6D5
TGPWSLILILFSVQY	COL4A4	21	P53420
GGLFVLTKYWQQIPL	ABCA13	2891	Q86UQ4
LIIGAWNYPFVLTIQ	ALDH3A2	106	P51648
WNYPFVLTIQPLIGA	ALDH3A2	111	P51648
AILLAFIITWAPYNV	CHRM2	391	P08172
LFWAPYNIVLLLNTF	CCR5	246	P51681
ASNALRQPYIWLTII	ATP8B1	1136	O43520
IPNDYLLSWLLFIAF	CNR2	186	P34972
TLWLFSNNLSTIYPG	RTN4RL2	86	Q86UN3
SYFTIWLNLELLLPV	PLA2G15	71	Q8NCC3
VPLLNSLAAYGWQLT	RFTN1	391	Q14699
QIILAIYFLWQNLGP	ABCC3	436	O15438
IYFLWQNLGPSVLAG	ABCC3	441	O15438
LLSPLLSLGQYLWAA	NUP133	846	Q8WUM0
TYIQWLFPLREQGLN	OGFRL1	156	Q5TC84
FLAVLLYLSAAVIWP	MYADML2	236	A6NDP7
QLVASPLLGVWYFLG	MPV17L2	106	Q567V2
TLLSQNFSVYLTWLP	IFNLR1	31	Q8IU57
GYLQPWAIILISLAA	MUC22	1656	E2RYF6
WLVTLSSAIYGLQPN	GPR158	281	Q5T848
LSILYSIGSKPLQIW	CFAP20	11	Q9Y6A4
VWGLELILFNSPEYQ	ATXN3	86	P54252
IYIFIPQNVQVLLWS	HPS5	311	Q9UPZ3
LNKPYLFSVLLGAWQ	PRSS22	96	Q9GZN4
TEPSILNNYLIWNLV	ECE2	426	P0DPD6
VFQSLEAYWPGLQSL	EDEM2	311	Q9BV94
LNSWYGFALALLIII	OR51Q1	196	Q8NH59
LLGVNNLEFNWLLPY	CES4A	346	Q5XG92
SYWLELLGPNNSLVA	NME5	91	P56597
LVQLPQHGQLYLWGT	FREM1	1546	Q5H8C1
AIVLWLGYANSALNP	HRH2	271	P25021
AILLPFVYLTAQVWI	LRRC4	16	Q9HBW1
VNLYTVNAPWLFSLL	GDPD5	451	Q8WTR4
LLYGTWIVAILQSTP	GPR101	151	Q96P66
QYSNWLLAGNLALSP	POGK	521	Q9P215
WQYVLLIPSVLQEGS	OVOS2	11	Q6IE36
LWLLSSNVYRNPFAI	MRGPRE	46	Q86SM8
ANLTWLNGCINPVLY	GPR84	356	Q9NQS5
ISLTWLLSPYIGNLS	PKD1L2	271	Q7Z442
QLLQWVGDFVLYLLA	MED16	616	Q9Y2X0
IYGWQLTLLLLAVVP	ABCB4	851	P21439
GLPSVFYWSLQPLLN	MRGPRG	211	Q86SM5
LGPILATILAQSYSW	SLC37A4	151	O43826
NLQLAIIWYFSPVST	CD101	706	Q93033
WGATVITNLLSAIPY	MT-CYB	141	P00156
LVTNAWVFLLLYIVP	GPRC5D	246	Q9NZD1
GLNPSLWYIIGIQFL	CACNA2D1	1076	P54289
FWTPYNLTILISVFQ	CCR1	251	P32246
TTGIILQWLQSDPYL	DHX36	311	Q9H2U1
WILLLLSLYPGFTSQ	GABRG2	26	P18507
SFQIYVLQAGAWPLT	CUL2	506	Q13617
FTWLGYLNSLINPII	HTR1D	341	P28221
LLLLLVQGLNCFWSY	CERS6	306	Q6ZMG9
NTGILFLPWGYDISQ	SELENOI	176	Q9C0D9
NLQIYGVLGLFWTLN	SLC44A4	441	Q53GD3
ENSPNYGLLLLWASL	CYP39A1	261	Q9NYL5
YGLLLLWASLSNAVP	CYP39A1	266	Q9NYL5
LTGYEVWLGTLFQNP	MST1	531	P26927
LLVNQYSLGNSLWFP	GRIK4	586	Q16099
LTGLPWSLYNTFVIE	ZMPSTE24	136	O75844
LTGIAYSLPHWQLLF	SLC22A14	286	Q9Y267
YSLPHWQLLFLVGGI	SLC22A14	291	Q9Y267
AQYLPGWTVLFLSVL	SLC22A31	416	A6NKX4
GTYNSLLIISWLPVL	RNF103	361	O00237
YSLVWFISPILGFLL	SLC45A1	156	Q9Y2W3
FPLGILLLFWVSYVT	SLC38A11	6	Q08AI6
GAVLVFLPGWNLIYT	DHX9	651	Q08211
PNGITLDLLSQRLYW	LRP8	586	Q14114
YTTSSIPQLLVNLWG	OR2J3	76	O76001
VLLLNWYSTVLNPAF	TAS2R43	61	P59537
VLLLNWYSTVLNPAF	TAS2R45	61	P59539
ALLLNWYLTVLNPAF	TAS2R50	61	P59544
AYQASNLPSLELLIW	SLC35G3	61	Q8N808
WIYFVNFLGTLAVLP	SV2C	581	Q496J9
LQSLALTWYSLSFIP	SFT2D2	131	O95562
LQVGLNTIADLWYLF	POMT2	251	Q9UKY4
SIPGFLVNYILVLWH	SLC9C1	111	Q4G0N8
FPFIISWISQLNVIY	SLC9C1	626	Q4G0N8
PTWAQTLIFQHLLLY	FER1L5	1121	A0AVI2
TESVLYLNGLWLPLV	ABCC6	421	O95255
FVYLWQLLGPSALTA	ABCC6	441	O95255
LAWLLAFVYNLPHTV	RNF26	36	Q9BY78
FLIIVPLSTLSNWAY	SMARCA4	806	P51532
VSSWGGYVFLINLIP	STT3A	206	P46977
TDLLSAIQFWLLYAP	TBATA	241	Q96M53
SFIPQQYFWLLVLSR	SPNS2	186	Q8IVW8
WNGLTANLLKIVPYF	SLC25A43	266	Q8WUT9
QNPVRLWQLLGGTFY	SPG7	86	Q9UQ90
ITSYLLQLLWPSNPG	NUP160	861	Q12769
FWLGLLYLVSPLENE	SPAG4	181	Q9NPE6
LGFLSLWYPVQLVRS	STRA6	216	Q9BX79
NSLYSVWPLVFLGIG	PIGW	201	Q7Z7B1
LGLVLPLWSDTQVYL	SSH3	161	Q8TE77
AILLAFIITWTPYNI	CHRM5	446	P08912
VGLALLTLIINPYWT	CLN8	236	Q9UBY8
LNPEWLVNYFGSLSV	CLTC	646	Q00610
AEWVTLGLNIPLLFY	CNIH2	86	Q6PI25
QEWLTLGLNVPLLFY	CNIH3	86	Q8TBE1
LGIPQSWRLYLVNLC	RNF213	666	Q63HN8
LGPWNIIFFITYEQL	SLC25A14	306	O95258
LSWGPYNFTLFLQTL	XCR1	236	P46094
LLNAWRTPYGASIFQ	TLE1	721	Q04724
LQQLYASLPVNGELW	ZFHX4	1411	Q86UP3
YTKLWTPLLQSLIGL	CSE1L	861	P55060
YLALANQVLSWNFLP	XPO4	226	Q9C0E2
VLLLGWLFAPVYLTA	SLC5A2	106	P31639
PWTQVGFSLLFLYLG	SLC27A4	21	Q6P1M0
PLALWSIIVNILLYF	TM4SF18	16	Q96CE8
SAWGGYVFIINLIPL	STT3B	261	Q8TCJ2
QVYQLVLPGSELLLW	ZNF408	156	Q9H9D4
PFLTTEVNNLGWLSY	SLC50A1	46	Q9BRV3
GNLLLILQYIWSFEL	PIEZO2	551	Q9H5I5
QRWLTYYPSGQLLIV	NDST2	761	P52849
YPTLLLTVWNFGAVG	PSEN2	201	P49810
YIKPGLSLSVALLWQ	KRT10-AS1	216	Q8N816
LGIPLTSQAGIYWLL	SLC6A9	511	P48067
LQRLIGNESFALPYW	DCT	231	P40126
LITHLGLPQWQYAFT	TPGS2	196	Q68CL5
YLVNNTPLNWLVGPF	PLIN2	391	Q99541
FLSTELAWLLPYNGV	GTF3C2	656	Q8WUA4
GPILDNYISALSALW	TGFB1I1	351	O43294
QVWIALYNLLLSPEA	ZMYND10	261	O75800
LTFNYLLPVNAWLLL	TMTC3	281	Q6ZXV5
QVLWAYVGLLSNPQA	TCTN3	501	Q6NUS6
GWLLTPNIYLSELFG	PIGM	81	Q9H3S5
ILLEPYLFWQILNGQ	TG	861	P01266
TRFQGVYLPLLWEQS	ZRANB1	556	Q9UGI0
TDPYLGLLLQQCWAT	ZP4	356	Q12836
TNLAAYVPLLTQGWA	TSC2	1181	P49815
SLLLVYGSWFQPTIE	WDR43	346	Q15061
WQLGLAFLPASVSYL	SLC18A1	336	P54219
LNWPYLKVLGQTFIT	WFS1	476	O76024