Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	coumarin 7-hydroxylase activity	CYP2A6 CYP2A7 CYP2A13	3.30e-07	3	139	3	GO:0008389
GeneOntologyMolecularFunction	steroid hydroxylase activity	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	3.60e-06	34	139	5	GO:0008395
GeneOntologyMolecularFunction	aromatase activity	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	4.17e-06	35	139	5	GO:0070330
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	2.27e-05	49	139	5	GO:0016712
GeneOntologyMolecularFunction	arachidonate monooxygenase activity	CYP2A6 CYP2A7 CYP2A13 CYP2D7	3.48e-05	27	139	4	GO:0008391
GeneOntologyMolecularFunction	beta-glucuronidase activity	HPSE KL	2.86e-04	4	139	2	GO:0004566
GeneOntologyMolecularFunction	oxidoreductase activity	CYP2A6 CYP2A7 CYP2A13 MSRB1 CYP2D7 HSDL2 CYP3A5 AOX1 ALDH1L1 DBT PRDX6 MTHFD1 KCNAB1 PDIA5 VCAM1	2.95e-04	766	139	15	GO:0016491
GeneOntologyMolecularFunction	arachidonate epoxygenase activity	CYP2A6 CYP2A7 CYP2A13	6.00e-04	24	139	3	GO:0008392
GeneOntologyBiologicalProcess	cell-matrix adhesion	TRPM7 NEXMIF SIRPB1 ITGAL HPSE ITGB3 TIAM1 TESK2 CDH13 VCAM1	1.61e-05	270	140	10	GO:0007160
GeneOntologyBiologicalProcess	phenylpropanoid metabolic process	CYP2A6 CYP2A7 CYP2A13	3.55e-05	10	140	3	GO:0009698
GeneOntologyBiologicalProcess	coumarin metabolic process	CYP2A6 CYP2A7 CYP2A13	3.55e-05	10	140	3	GO:0009804
GeneOntologyBiologicalProcess	nuclear pore complex assembly	AHCTF1 RTN4 NUP153	4.85e-05	11	140	3	GO:0051292
MousePheno	abnormal intestinal lipid absorption	CYP2A6 CYP2A7 CYP2A13 PITPNA C3	4.16e-06	31	111	5	MP:0005342
MousePheno	abnormal CNS synaptic transmission	NEXMIF SMCHD1 RTN4 PPP1R9A BCORL1 SIRPB1 GRIN2A HNRNPAB PDLIM5 PCDH17 PPM1G USP14 SBF1 NRXN2 ANKRD11 KCNAB1 C3 RIMBP2 PCM1 NOVA2	8.60e-05	985	111	20	MP:0002206
MousePheno	abnormal synaptic transmission	TRPM7 NEXMIF SMCHD1 RTN4 PPP1R9A BCORL1 SIRPB1 GRIN2A HNRNPAB PDLIM5 PCDH17 PPM1G USP14 SBF1 NRXN2 ANKRD11 KCNAB1 C3 RIMBP2 PCM1 NOVA2	9.05e-05	1070	111	21	MP:0003635
MousePheno	abnormal synaptic physiology	TRPM7 NEXMIF SMCHD1 RTN4 PPP1R9A BCORL1 SIRPB1 GRIN2A HNRNPAB PDLIM5 PCDH17 PPM1G USP14 SBF1 NRXN2 ANKRD11 KCNAB1 C3 RIMBP2 PCM1 NOVA2	9.79e-05	1076	111	21	MP:0021009
MousePheno	abnormal intestinal absorption	CYP2A6 CYP2A7 CYP2A13 PITPNA C3	1.03e-04	59	111	5	MP:0001666
MousePheno	decreased lumbar vertebrae number	SF3B4 SGO1 ARL4D AKAP9	1.29e-04	33	111	4	MP:0004647
Domain	FRG2	FRG2 FRG2C FRG2B	4.12e-07	3	140	3	PF15315
Domain	FRG2	FRG2 FRG2C FRG2B	4.12e-07	3	140	3	IPR026245
Domain	Cyt_P450_E_grp-I_CYP2A-like	CYP2A6 CYP2A7 CYP2A13	1.64e-06	4	140	3	IPR008067
Domain	CSP	LIN28B LIN28A CSDE1	2.25e-05	8	140	3	SM00357
Domain	Cold_shock_prot	LIN28B LIN28A CSDE1	2.25e-05	8	140	3	IPR011129
Domain	CSD	LIN28B LIN28A CSDE1	2.25e-05	8	140	3	PF00313
Domain	CSP_DNA-bd	LIN28B LIN28A CSDE1	2.25e-05	8	140	3	IPR002059
Domain	CA	DCHS2 PCDHAC1 PCDHA10 PCDHA2 PCDH17 FREM2 CDH13	2.55e-05	115	140	7	SM00112
Domain	Cadherin	DCHS2 PCDHAC1 PCDHA10 PCDHA2 PCDH17 FREM2 CDH13	3.02e-05	118	140	7	IPR002126
Domain	Cadherin_CS	DCHS2 PCDHAC1 PCDHA10 PCDHA2 PCDH17 CDH13	1.71e-04	109	140	6	IPR020894
Domain	CADHERIN_1	DCHS2 PCDHAC1 PCDHA10 PCDHA2 PCDH17 CDH13	2.09e-04	113	140	6	PS00232
Domain	Cadherin	DCHS2 PCDHAC1 PCDHA10 PCDHA2 PCDH17 CDH13	2.09e-04	113	140	6	PF00028
Domain	CADHERIN_2	DCHS2 PCDHAC1 PCDHA10 PCDHA2 PCDH17 CDH13	2.19e-04	114	140	6	PS50268
Domain	-	DCHS2 PCDHAC1 PCDHA10 PCDHA2 PCDH17 CDH13	2.19e-04	114	140	6	2.60.40.60
Domain	Cadherin-like	DCHS2 PCDHAC1 PCDHA10 PCDHA2 PCDH17 CDH13	2.40e-04	116	140	6	IPR015919
Domain	Cyt_P450_E_grp-I	CYP2A6 CYP2A7 CYP2A13 CYP3A5	3.55e-04	45	140	4	IPR002401
Domain	Cyt_P450_CS	CYP2A6 CYP2A7 CYP2A13 CYP3A5	6.66e-04	53	140	4	IPR017972
Pathway	REACTOME_XENOBIOTICS	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	7.33e-07	25	99	5	MM14846
Pathway	REACTOME_CYP2E1_REACTIONS	CYP2A6 CYP2A7 CYP2A13 CYP2D7	1.08e-06	12	99	4	MM14847
Pathway	REACTOME_FATTY_ACIDS	CYP2A6 CYP2A7 CYP2A13 CYP2D7	6.49e-06	18	99	4	MM14841
Pathway	REACTOME_XENOBIOTICS	CYP2A6 CYP2A7 CYP2A13 CYP3A5	1.83e-05	23	99	4	M5372
Pathway	REACTOME_CYP2E1_REACTIONS	CYP2A6 CYP2A7 CYP2A13	5.32e-05	11	99	3	M27130
Pathway	REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	9.82e-05	66	99	5	MM14839
Pathway	KEGG_DRUG_METABOLISM_CYTOCHROME_P450	CYP2A6 CYP2A7 CYP2A13 CYP3A5 AOX1	1.49e-04	72	99	5	M9257
Pathway	WP_CELLS_AND_MOLECULES_INVOLVED_IN_LOCAL_ACUTE_INFLAMMATORY_RESPONSE	ITGAL C3 VCAM1	2.13e-04	17	99	3	M39733
Pathway	BIOCARTA_LAIR_PATHWAY	ITGAL C3 VCAM1	2.13e-04	17	99	3	M3952
Pathway	KEGG_DRUG_METABOLISM_OTHER_ENZYMES	CYP2A6 CYP2A7 CYP2A13 CYP3A5	4.44e-04	51	99	4	M17726
Pathway	KEGG_MEDICUS_ENV_FACTOR_NNK_TO_DNA_ADDUCTS	CYP2A6 CYP2A13	4.82e-04	5	99	2	M47808
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	GTPBP4 COL5A1 NOP53 SMCHD1 AHCTF1 U2SURP UBR4 NVL MCM6 PPM1G CSDE1 SBF1 MKI67 ANKRD17 PYGL TAF15 RPL3 PCM1 NUP153	3.33e-11	653	144	19	22586326
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	IRF2BP2 SF3B4 MCM6 GPATCH8 DNAJC7 HNRNPAB PDLIM5 PPM1G CSDE1 ATG3 MKI67 TAF15 SF3A2 CA2	1.39e-09	399	144	14	35987950
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	GTPBP4 NOP53 SMCHD1 U2SURP MCM6 MACROH2A1 GPATCH8 SRFBP1 DNAJC7 HNRNPAB PRDX6 PPM1G YARS2 MTHFD1 MKI67 TAF15 RPL3 SF3A2 VARS1 NUP153	5.38e-09	989	144	20	36424410
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	JCAD EMC1 CNST DNAJC16 RTN4 U2SURP UBR4 MACROH2A1 GRIN2A DBT HNRNPAB PPM1G VANGL2 CSDE1 CDKL5 KCNB1 MTHFD1 KCNAB1 VARS1 PCM1 RASAL1	1.08e-08	1139	144	21	36417873
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	GTPBP4 IRF2BP2 SMCHD1 AHCTF1 RTN4 U2SURP MACROH2A1 HNRNPAB PDLIM5 PRDX6 CSDE1 USP14 MTHFD1 MKI67 ANKRD17 TAF15 RPL3 PCM1 NUP153	1.22e-08	934	144	19	33916271
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GTPBP4 EMC1 HSDL2 NOP53 SMCHD1 RTN4 U2SURP UBR4 MCM6 MACROH2A1 DBT DNAJC7 CCDC38 HNRNPAB PRDX6 YARS2 MTHFD1 MKI67 RPL3 VARS1 NUP153 CA2 MYBPC1	2.35e-08	1425	144	23	30948266
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	GTPBP4 SF3B4 HSDL2 SMCHD1 AHCTF1 U2SURP UBR4 MCM6 MACROH2A1 DBT HNRNPAB PRDX6 CSDE1 MTHFD1 MKI67 PYGL TAF15 RPL3 SF3A2 VARS1 NUP153 CA2	2.73e-08	1318	144	22	30463901
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	GTPBP4 AHCTF1 U2SURP MCM6 MACROH2A1 HNRNPAB CSDE1 MTHFD1 MKI67 PYGL TAF15 RPL3 NUP153	4.30e-08	441	144	13	31239290
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	GTPBP4 IRF2BP2 SMCHD1 UBR4 NVL MCM6 MACROH2A1 GPATCH8 DNAJC7 PRDX6 PPM1G CSDE1 USP14 ATG3 MKI67 PYGL TAF15 SF3A2 NUP153	4.47e-08	1014	144	19	32416067
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	GTPBP4 EMC1 TRPM7 HSDL2 DNAJC16 AHCTF1 RTN4 UBR4 NVL MACROH2A1 DBT DNAJC7 PPM1G VANGL2 AKAP9 SBF1 TIAM1 ANKRD11 PDIA5 TAF15 RPL3 PCM1 TPD52	5.10e-08	1487	144	23	33957083
Pubmed	Regulation of bile acid metabolism in mouse models with hydrophobic bile acid composition.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	31645370
Pubmed	A trans-acting locus regulates transcriptional repression of the female-specific steroid 15 alpha-hydroxylase gene in male mice.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	8297477
Pubmed	Lack of the steroid 15 alpha-hydroxylase gene (Cyp2a-4) in wild mouse strain Mus spretus: rapid evolution of the P450 gene superfamily.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	8188299
Pubmed	Comparison of hamster and mouse reveals interspecies differences in the regulation of hepatic CYP2A isozymes.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	8250953
Pubmed	The structure and characterization of type I P-450(15) alpha gene as major steroid 15 alpha-hydroxylase and its comparison with type II P-450(15) alpha gene.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	2703500
Pubmed	Alteration of the substrate specificity of mouse 2A P450s by the identity of residue-209: steroid-binding site and orientation.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	22217847
Pubmed	Differential distribution of CYP2A6 and CYP2A13 in the human respiratory tract.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	22890016
Pubmed	Reciprocal regulation of sex-dependent expression of testosterone 15 alpha-hydroxylase (P-450(15 alpha)) in liver and kidney of male mice by androgen. Evidence for a single gene.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	3346244
Pubmed	Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	2733794
Pubmed	Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	8484736
Pubmed	Cerium-induced strain-dependent increase in Cyp2a-4/5 (cytochrome P4502a-4/5) expression in the liver and kidneys of inbred mice.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	1417950
Pubmed	Impact of nicotine metabolism on nicotine's pharmacological effects and behavioral responses: insights from a Cyp2a(4/5)bgs-null mouse.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	24045421
Pubmed	Highly homologous mouse Cyp2a4 and Cyp2a5 genes are differentially expressed in the liver and both express long non-coding antisense RNAs.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	32987105
Pubmed	Mouse steroid 15 alpha-hydroxylase gene family: identification of type II P-450(15)alpha as coumarin 7-hydroxylase.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	2765478
Pubmed	Sexual dimorphism of testosterone 15 alpha-hydroxylase mRNA levels in mouse liver. cDNA cloning and regulation.	CYP2A6 CYP2A7 CYP2A13	6.95e-08	3	144	3	2415518
Pubmed	FRG2, an FSHD candidate gene, is transcriptionally upregulated in differentiating primary myoblast cultures of FSHD patients.	FRG2 FRG2C FRG2B	6.95e-08	3	144	3	15520407
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SF3B4 ARID4B LIN28B NOP53 SMCHD1 AHCTF1 U2SURP BCORL1 NVL MACROH2A1 SRFBP1 HNRNPAB RECQL5 MKI67 ANKRD11 TAF15 PCM1 NUP153	9.41e-08	954	144	18	36373674
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	GTPBP4 COL5A1 SF3B4 EMC1 NOP53 SMCHD1 RTN4 U2SURP UBR4 NCOA4 DNAJC7 HNRNPAB CSDE1 COA6 MTHFD1 MKI67 PDIA5 C3 RPL3 SF3A2 PCM1	9.75e-08	1297	144	21	33545068
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	GTPBP4 EMC1 SMCHD1 U2SURP PPP1R9A MCM6 MACROH2A1 DNAJC7 HNRNPAB PRDX6 MTHFD1 MKI67 TAF15 RPL3 SF3A2 VARS1 PCM1 NUP153	2.67e-07	1024	144	18	24711643
Pubmed	Circadian expression of the steroid 15 alpha-hydroxylase (Cyp2a4) and coumarin 7-hydroxylase (Cyp2a5) genes in mouse liver is regulated by the PAR leucine zipper transcription factor DBP.	CYP2A6 CYP2A7 CYP2A13	2.77e-07	4	144	3	10490589
Pubmed	Two steroid 15 alpha-hydroxylase genes and a homologous gene family in mice.	CYP2A6 CYP2A7 CYP2A13	2.77e-07	4	144	3	1970547
Pubmed	Transcriptional regulation by HNF-4 of the steroid 15alpha-hydroxylase P450 (Cyp2a-4) gene in mouse liver.	CYP2A6 CYP2A7 CYP2A13	2.77e-07	4	144	3	9408084
Pubmed	A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP.	CYP2A6 CYP2A7 CYP2A13	2.77e-07	4	144	3	7565685
Pubmed	Establishment and analysis of a mouse model that regulates sex-related differences in liver drug metabolism.	CYP2A6 CYP2A7 CYP2A13 CYP3A5	3.71e-07	15	144	4	29968852
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RTN4 PPP1R9A GRIN2A ALDH1L1 HDHD2 HNRNPAB PDLIM5 PRDX6 CSDE1 CDKL5 SBF1 NRXN2 MTHFD1 RIMBP2 TAF15 KIF5C RPL3 VARS1 PCM1 RASAL1 CA2	4.90e-07	1431	144	21	37142655
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	GTPBP4 PPP1R9A UBR4 MACROH2A1 SIRPB1 GRIN2A AKAP9 SBF1 KCNB1 KCNAB1 ANKRD17 RIMBP2 TAF15 KIF5C PCM1 NUP153 RASAL1	5.54e-07	963	144	17	28671696
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	GTPBP4 EMC1 NOP53 RTN4 U2SURP MCM6 ITGAL PPM1G CSDE1 ATG3 NADK PDIA5 TAF15 SF3A2	6.17e-07	653	144	14	33742100
Pubmed	Zinc Fingers and Homeoboxes 2 (Zhx2) Regulates Sexually Dimorphic Cyp Gene Expression in the Adult Mouse Liver.	CYP2A6 CYP2A7 CYP2A13 CYP3A5	6.43e-07	17	144	4	27197076
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	SF3B4 RTN4 PPP1R9A UBR4 DBT SGO1 DNAJC7 PRDX6 PPM1G VANGL2 MKI67 PYGL RPL3	8.48e-07	573	144	13	28330616
Pubmed	LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans.	LIN28B MCM6 LIN28A TIAM1	1.04e-06	19	144	4	25956904
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	GTPBP4 SF3B4 RTN4 U2SURP MCM6 DBT DNAJC7 ZC3H6 PDLIM5 PRDX6 USP14 AKAP9 MTHFD1 MKI67 ANKRD17 TAF15 RPL3 SF3A2 VARS1	1.04e-06	1247	144	19	27684187
Pubmed	Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	1.08e-06	44	144	5	12745259
Pubmed	Molecular genetics of the human cytochrome P450 monooxygenase superfamily.	CYP2A6 CYP2A7 CYP2A13 CYP3A5	1.30e-06	20	144	4	9890157
Pubmed	A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles.	CYP2A6 CYP2A7 CYP2A13	1.38e-06	6	144	3	7668294
Pubmed	Akhirin regulates the proliferation and differentiation of neural stem cells/progenitor cells at neurogenic niches in mouse brain.	VIT MKI67 VCAM1	1.38e-06	6	144	3	31943155
Pubmed	Organization and evolution of the cytochrome P450 CYP2A-2B-2F subfamily gene cluster on human chromosome 19.	CYP2A6 CYP2A7 CYP2A13	1.38e-06	6	144	3	8587134
Pubmed	Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.	TRPM7 DNAJC16 RTN4 PDLIM5 VANGL2 CSDE1 MKI67 NUP153	1.42e-06	191	144	8	31177093
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	GTPBP4 IRF2BP2 SF3B4 AHCTF1 U2SURP MACROH2A1 PRDX6 MTHFD1 MKI67 RPL3 SF3A2 NUP153	1.44e-06	506	144	12	30890647
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	JCAD SF3B4 EMC1 HSDL2 NOP53 PPP1R9A DBT SRFBP1 SGO1 DNAJC7 PPM1G AKAP9 SBF1 TIAM1 MKI67 NUP153 TPD52	1.77e-06	1049	144	17	27880917
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CYP2A6 MYH4 CYP2A13 SMCHD1 U2SURP PPP1R9A UBR4 MACROH2A1 PDE10A SGO1 DNAJC7 HNRNPAB FER1L6 GNA12 TAF15 KIF5C RPL3 SF3A2 VARS1 MYBPC1	2.23e-06	1442	144	20	35575683
Pubmed	Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses.	CYP2A6 CYP2A7 CYP2A13	2.40e-06	7	144	3	9630227
Pubmed	Organization and evolution of the Cyp2 gene cluster on mouse chromosome 7, and comparison with the syntenic human cluster.	CYP2A6 CYP2A7 CYP2A13	2.40e-06	7	144	3	14630516
Pubmed	The folate metabolic enzyme ALDH1L1 is restricted to the midline of the early CNS, suggesting a role in human neural tube defects.	ALDH1L1 MTHFD1 MKI67	2.40e-06	7	144	3	17111379
Pubmed	Lin28a regulates germ cell pool size and fertility.	LIN28B LIN28A MKI67	2.40e-06	7	144	3	23378032
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	HSDL2 SMCHD1 UBR4 MCM6 DNAJC7 CSDE1 USP14 MTHFD1 ANKRD17 VARS1 NUP153 CA2	2.51e-06	534	144	12	35032548
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	GTPBP4 SF3B4 EMC1 U2SURP MACROH2A1 GPATCH8 DBT ZC3H6 HNRNPAB VANGL2 SBF1 NRXN2 PDIA5 GNA12 TAF15 SF3A2 VARS1	2.69e-06	1082	144	17	38697112
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	GTPBP4 SF3B4 DNAJC16 UBR4 MCM6 DNAJC7 HNRNPAB PRDX6 CSDE1 MTHFD1 RPL3 VARS1 NUP153	2.77e-06	638	144	13	33239621
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	SMCHD1 AHCTF1 NVL SRFBP1 PPM1G USP14 MKI67 TAF15 NUP153	3.00e-06	283	144	9	30585729
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	EMC1 DNAJC16 SMCHD1 RTN4 UBR4 MCM6 PPM1G VANGL2 SBF1 ANKRD17 PYGL C3 RPL3 VARS1 PCM1 NUP153	3.07e-06	974	144	16	28675297
Pubmed	Global landscape of HIV-human protein complexes.	EMC1 RTN4 UBR4 MCM6 DNAJC7 ITGAL PPM1G CSDE1 AKAP9 ANKRD17 PDIA5	3.49e-06	457	144	11	22190034
Pubmed	Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.	RTN4 MCM6 DBT PRDX6 CSDE1 ATG3 MTHFD1 PYGL RPL3 CA2	4.21e-06	377	144	10	25147182
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	GTPBP4 IRF2BP2 SMCHD1 U2SURP UBR4 NVL MCM6 GPATCH8 PRDX6 CSDE1 PYGL VARS1 PCM1	4.33e-06	665	144	13	30457570
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	MYH4 LIN28B NOP53 PPP1R9A MCM6 DBT PPM1G YARS2 USP14 ANKRD17 PYGL RIMBP2 SF3A2 VARS1 NUP153 CA2	4.57e-06	1005	144	16	19615732
Pubmed	Chromosomal assignments of genes coding for components of the mixed-function oxidase system in mice. Genetic localization of the cytochrome P-450PCN and P-450PB gene families and the nadph-cytochrome P-450 oxidoreductase and epoxide hydratase genes.	CYP2A6 CYP2A13 CYP3A5	5.73e-06	9	144	3	3917435
Pubmed	Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder.	CYP2A6 CYP2A7 CYP2A13	5.73e-06	9	144	3	37838304
Pubmed	Lin28 sustains early renal progenitors and induces Wilms tumor.	LIN28B LIN28A MKI67	5.73e-06	9	144	3	24732380
Pubmed	ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.	MCM6 ARMCX5 PPM1G MTHFD1 TAF15 VARS1 CA2	6.31e-06	166	144	7	35687106
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	GTPBP4 MYH4 SF3B4 EMC1 RTN4 UBR4 GPATCH8 DBT HNRNPAB YARS2 TIAM1 ATG3 MTHFD1 PITPNA NADK KIF5C RPL3 VARS1	6.49e-06	1284	144	18	17353931
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	GTPBP4 SF3B4 LIN28B NOP53 U2SURP GPATCH8 SRFBP1 HNRNPAB YARS2 CSDE1 TAF15 RPL3 SF3A2 NOVA2	7.15e-06	807	144	14	22681889
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	GTPBP4 TICRR SF3B4 ARID4B SMCHD1 AHCTF1 U2SURP BCORL1 GPATCH8 SRFBP1 HNRNPAB RECQL5 MKI67 ANKRD11 TAF15 RPL3 SF3A2 NUP153	7.22e-06	1294	144	18	30804502
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	MCM6 HNRNPAB PDLIM5 CSDE1 MTHFD1 MKI67 PYGL TAF15 RPL3 VARS1 NUP153	7.29e-06	494	144	11	26831064
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	IRF2BP2 DCHS2 RTN4 U2SURP MACROH2A1 ALDH1L1 DNAJC7 MTHFD1 ANKRD11 RBM46 HYDIN	7.71e-06	497	144	11	36774506
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	GTPBP4 HSDL2 SMCHD1 AHCTF1 UBR4 MACROH2A1 HNRNPAB PRDX6 PDIA5 C3 TAF15 RPL3 VARS1	8.86e-06	711	144	13	33022573
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	GTPBP4 NOP53 AHCTF1 U2SURP PPP1R9A MCM6 MACROH2A1 HNRNPAB CSDE1 MTHFD1 MKI67 C3 RPL3 SF3A2 VARS1	1.01e-05	949	144	15	36574265
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	GTPBP4 NOP53 U2SURP NVL MACROH2A1 PPM1G ANKRD17 SF3A2	1.06e-05	251	144	8	28077445
Pubmed	Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.	U2SURP MCM6 CSDE1 C3 TAF15 SF3A2 VARS1	1.07e-05	180	144	7	30110629
Pubmed	Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	1.11e-05	70	144	5	15128046
Pubmed	Lin28 promotes the proliferative capacity of neural progenitor cells in brain development.	LIN28B LIN28A MKI67	1.12e-05	11	144	3	25922525
Pubmed	A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.	AHCTF1 U2SURP MACROH2A1 PPM1G MKI67 NUP153	1.18e-05	121	144	6	22412018
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	GTPBP4 COL5A1 SF3B4 NOP53 AHCTF1 U2SURP NVL HNRNPAB MKI67 ANKRD17 TAF15 RPL3 SF3A2 NUP153	1.23e-05	847	144	14	35850772
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	SIRPB1 ITGB3 F13A1 FREM2 C2 C3 CDH13 VCAM1	1.26e-05	257	144	8	16335952
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	GTPBP4 SMCHD1 AHCTF1 U2SURP UBR4 MCM6 MACROH2A1 HNRNPAB CSDE1 USP14 SBF1 MTHFD1 RECQL5 MKI67 ANKRD17 PYGL RPL3 VARS1	1.32e-05	1353	144	18	29467282
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	UBR4 MCM6 ITGB3 PDLIM5 MTHFD1 NADK C3 VARS1 CA2	1.44e-05	344	144	9	30333137
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	JCAD SF3B4 EMC1 TRPM7 AKAP9 SBF1 TIAM1 TESK2 ANKRD11 NADK ANKRD17 KIF5C PCM1 CCSER1	1.48e-05	861	144	14	36931259
Pubmed	RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development.	PDLIM5 MKI67 PCM1	1.49e-05	12	144	3	35472321
Pubmed	Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.	GTPBP4 U2SURP MCM6 MACROH2A1 CSDE1 MTHFD1 MKI67 TAF15 KIF5C RPL3 VARS1 NUP153	1.58e-05	641	144	12	36057605
Pubmed	LIN28 expression and function in medulloblastoma.	LIN28B LIN28A	1.70e-05	2	144	2	36649308
Pubmed	Lin28B and Let-7 in the Control of Sympathetic Neurogenesis and Neuroblastoma Development.	LIN28B LIN28A	1.70e-05	2	144	2	26674877
Pubmed	Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity.	CYP2A6 CYP2A7	1.70e-05	2	144	2	12325023
Pubmed	Hypermethylations of RASAL1 and KLOTHO is associated with renal dysfunction in a Chinese population environmentally exposed to cadmium.	KL RASAL1	1.70e-05	2	144	2	23665422
Pubmed	Suppressed hepatocyte proliferation via a ROS-HNE-P21 pathway is associated with nicotine- and cotinine-enhanced alcoholic fatty liver in mice.	CYP2A6 CYP2A13	1.70e-05	2	144	2	30876690
Pubmed	CYP2A5 induction and hepatocellular stress: an adaptive response to perturbations of heme homeostasis.	CYP2A6 CYP2A13	1.70e-05	2	144	2	21395539
Pubmed	Species differences in coumarin metabolism: a molecular modelling evaluation of CYP2A interactions.	CYP2A6 CYP2A13	1.70e-05	2	144	2	12162851
Pubmed	Molecular characterization of the murine Coh locus: an amino acid difference at position 117 confers high and low coumarin 7-hydroxylase activity in P450coh.	CYP2A6 CYP2A13	1.70e-05	2	144	2	1302041
Pubmed	Comparison of the expression and function of Lin28A and Lin28B in colon cancer.	LIN28B LIN28A	1.70e-05	2	144	2	27793004
Pubmed	Structural alteration of mouse P450coh by mutation of glycine-207 to proline: spin equilibrium, enzyme kinetics, and heat sensitivity.	CYP2A6 CYP2A13	1.70e-05	2	144	2	8395817
Pubmed	Sex-specific regulation of weight and puberty by the Lin28/let-7 axis.	LIN28B LIN28A	1.70e-05	2	144	2	26698568
Pubmed	Absence of cytochrome P450 2A5 enhances alcohol-induced liver injury in mice.	CYP2A6 CYP2A13	1.70e-05	2	144	2	25804444
Pubmed	Effect of pyrazole, cobalt and phenobarbital on mouse liver cytochrome P-450 2a-4/5 (Cyp2a-4/5) expression.	CYP2A6 CYP2A13	1.70e-05	2	144	2	1520280
Pubmed	Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a CYP2A13-humanized mouse model.	CYP2A6 CYP2A13	1.70e-05	2	144	2	23917075
Interaction	CYP2A7 interactions	CYP2A6 CYP2A7 CYP2A13	3.35e-07	3	141	3	int:CYP2A7
Interaction	SIRT7 interactions	GTPBP4 COL5A1 NOP53 SMCHD1 AHCTF1 U2SURP UBR4 NVL MCM6 PPM1G CSDE1 SBF1 MKI67 ANKRD17 PYGL TAF15 RPL3 PCM1 NUP153	1.10e-06	744	141	19	int:SIRT7
Interaction	HNRNPU interactions	GTPBP4 NVL MCM6 PCDHA2 MACROH2A1 DBT ITGAL MAP10 HNRNPAB YARS2 CSDE1 USP14 ATG3 TAF15 CPLANE1 RPL3 SF3A2 VARS1 HYDIN VCAM1 NUP153 TPD52	3.04e-06	1035	141	22	int:HNRNPU
Interaction	PPP1CA interactions	IRF2BP2 SF3B4 CNST NOP53 AHCTF1 PPP1R9A DBT PDLIM5 PPM1G CDKL5 USP14 AKAP9 MKI67 PYGL SF3A2 VCAM1 NUP153	7.62e-06	696	141	17	int:PPP1CA
Interaction	GRIA2 interactions	EMC1 CNST DNAJC16 RTN4 MACROH2A1 GRIN2A NCOA4 ITGB3 CDKL5	1.33e-05	203	141	9	int:GRIA2
Interaction	CEBPB interactions	GTPBP4 TICRR SF3B4 SMCHD1 AHCTF1 U2SURP TIGD1 MCM6 MACROH2A1 GPATCH8 DNAJC7 HNRNPAB PRDX6 PPM1G CSDE1 USP14 AKAP9 MTHFD1 MKI67 PYGL RPL3 SF3A2 VARS1 NUP153 TPD52	2.14e-05	1443	141	25	int:CEBPB
Interaction	HUWE1 interactions	EMC1 RTN4 MCM6 MACROH2A1 DBT NCOA4 DNAJC7 ITGB3 HNRNPAB PRDX6 PPM1G CSDE1 AKAP9 ATG3 MTHFD1 PYGL KIF5C RPL3 VARS1 NUP153 CA2	3.02e-05	1110	141	21	int:HUWE1
Interaction	PRPF8 interactions	SF3B4 EMC1 U2SURP UBR4 DNAJC7 ITGB3 HNRNPAB PRDX6 PPM1G USP14 MTHFD1 MKI67 GPR156 RPL3 SF3A2 VARS1 VCAM1	3.08e-05	776	141	17	int:PRPF8
Interaction	U2SURP interactions	SF3B4 LIN28B SMCHD1 U2SURP UBR4 MACROH2A1 LIN28A PPM1G USP14 TAF15 SF3A2	3.56e-05	349	141	11	int:U2SURP
Interaction	PABPC4L interactions	LIN28B NOP53 LIN28A CSDE1 RPL3	3.75e-05	54	141	5	int:PABPC4L
Interaction	IFI16 interactions	GTPBP4 NOP53 SMCHD1 AHCTF1 U2SURP PPP1R9A NVL MCM6 MACROH2A1 HNRNPAB PPM1G CIITA MKI67 RPL3 VARS1 NUP153	4.09e-05	714	141	16	int:IFI16
Interaction	NCL interactions	GTPBP4 SF3B4 ARID4B NOP53 U2SURP UBR4 MACROH2A1 ITGB3 LIN28A HNRNPAB PDLIM5 ARL4D MTHFD1 RECQL5 RBM46 RPL3 VCAM1	4.36e-05	798	141	17	int:NCL
Interaction	BIRC3 interactions	GTPBP4 EMC1 HSDL2 NOP53 SMCHD1 RTN4 U2SURP UBR4 MCM6 MACROH2A1 DBT DNAJC7 CCDC38 HNRNPAB PRDX6 YARS2 MTHFD1 MKI67 RPL3 VARS1 NUP153 CA2 MYBPC1	5.17e-05	1334	141	23	int:BIRC3
Interaction	NAA40 interactions	GTPBP4 IRF2BP2 SMCHD1 AHCTF1 RTN4 U2SURP MACROH2A1 HNRNPAB PDLIM5 PRDX6 CSDE1 USP14 MTHFD1 MKI67 ANKRD17 TAF15 RPL3 PCM1 NUP153	5.26e-05	978	141	19	int:NAA40
Interaction	SMC5 interactions	MYH4 SF3B4 ARID4B LIN28B NOP53 SMCHD1 AHCTF1 U2SURP BCORL1 NVL MACROH2A1 SRFBP1 HNRNPAB RECQL5 MKI67 ANKRD11 TAF15 PCM1 NUP153	7.08e-05	1000	141	19	int:SMC5
Interaction	ZNF330 interactions	GTPBP4 ARID4B NOP53 SMCHD1 BCORL1 NVL MACROH2A1 GPATCH8 SRFBP1 PPM1G RECQL5 ANKRD11	7.22e-05	446	141	12	int:ZNF330
Interaction	STIP1 interactions	GTPBP4 IRF2BP2 SF3B4 DNAJC16 UBR4 MCM6 DNAJC7 HPSE HNRNPAB PRDX6 LRRC9 CSDE1 CFAP52 SBF1 MTHFD1 RPL3 VARS1 VCAM1 NUP153	7.66e-05	1006	141	19	int:STIP1
Interaction	SNRNP200 interactions	SF3B4 UBR4 MACROH2A1 ITGB3 ARL4D USP14 MKI67 GPR156 TAF15 SF3A2 VARS1 VCAM1	9.68e-05	460	141	12	int:SNRNP200
Interaction	NR2C2 interactions	GTPBP4 SF3B4 HSDL2 SMCHD1 AHCTF1 U2SURP UBR4 MCM6 MACROH2A1 DBT HPSE HNRNPAB PRDX6 CSDE1 MTHFD1 MKI67 PYGL TAF15 RPL3 SF3A2 VARS1 NUP153 CA2	1.11e-04	1403	141	23	int:NR2C2
Interaction	MAK16 interactions	GTPBP4 NOP53 NVL LIN28A ATG3 MKI67 RPL3	1.46e-04	162	141	7	int:MAK16
Interaction	OAS3 interactions	GTPBP4 NOP53 ITGB3 PPM1G MKI67	1.50e-04	72	141	5	int:OAS3
Interaction	NEURL4 interactions	HSDL2 GRIN2A NCOA4 SGO1 DNAJC7 PCM1	1.66e-04	116	141	6	int:NEURL4
GeneFamily	Cytochrome P450 family 2	CYP2A6 CYP2A7 CYP2A13 CYP2D7	4.04e-05	35	100	4	1001
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	CNST PPP1R9A AKAP9 MKI67 RIMBP2 HYDIN	5.07e-04	181	100	6	694
Coexpression	FEVR_CTNNB1_TARGETS_DN	GTPBP4 CYP3A5 U2SURP MCM6 MACROH2A1 NCOA4 HNRNPAB USP14 COA6 TIAM1 MTHFD1 MKI67 RPL3 CA2	2.45e-06	555	144	14	M2343
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL3	HSDL2 MUC19 GRIN2A PDLIM5 FREM2 CFAP52 KCNAB1 PYGL GNA12 KIF5C HYDIN CDH13 VCAM1	1.79e-05	574	144	13	M39056
Coexpression	MURARO_PANCREAS_BETA_CELL	IRF2BP2 NEXMIF AHCTF1 RTN4 U2SURP NCOA4 ZC3H6 FAM200B SLC2A2 ARL4D CSDE1 TIAM1 ATG3 KIF5C RPL3 PCM1 TPD52	1.83e-05	946	144	17	M39169
CoexpressionAtlas	Myeloid Cells, Mo.6C+II-.BM, B220neg CD3neg CD115+ Ly-6C+, Bone marrow, avg-3	MSRB1 SIRPB1 HPSE F13A1 PYGL C3	6.55e-06	69	141	6	GSM854329_100
CoexpressionAtlas	B cells, proB.FrA.BM, CD19- IgM- CD43+ CD24- AA4.1+ CD45R+ CD117+ IL7R+, Bone marrow, avg-1	TICRR MSRB1 MCM6 MACROH2A1 SIRPB1 F13A1 SLCO4C1 MKI67 PYGL C3 TPD52	6.81e-05	395	141	11	GSM538351_500
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000	GTPBP4 TICRR LIN28B MUC19 NVL SRFBP1 ITGB3 SLCO4C1 MTHFD1 TESK2 RBM46 HFM1 RIMBP2 DEPDC7 VARS1 NUP153	7.87e-05	795	141	16	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlas	B cells, proB.CLP.BM, CD19- IgM- CD43+ CD24- AA4.1+ CD45R- CD117+ IL7R+, Bone marrow, avg-1	TICRR MSRB1 MCM6 MACROH2A1 SIRPB1 F13A1 SLCO4C1 MKI67 PYGL C3 CA2	8.50e-05	405	141	11	GSM538343_500
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_1000	LIN28B GPATCH8 ZC3H6 HFM1 DEPDC7 CPLANE1	9.37e-05	110	141	6	gudmap_dev gonad_e13.5_M_GermCell_Oct_k4_1000
ToppCell	droplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MSRB1 ITGAL F13A1 LGALS2 LRRC9 NADK C3 TPD52	6.49e-08	164	144	8	cd0794f84dfd346807e2d803723718b7f22e9232
ToppCell	droplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MSRB1 ITGAL F13A1 LGALS2 LRRC9 NADK C3 TPD52	6.49e-08	164	144	8	12251a49fd4af32d4edb58046245548c260cf04b
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VIT SGO1 LGALS2 FREM2 MKI67 C2 C3 MYBPC1	1.22e-07	178	144	8	c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LIN28B PPP1R9A FREM2 CFAP54 RIMBP2 KIF5C TPD52 CCSER1	2.01e-07	190	144	8	625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCell	Adult-Mesenchymal-chondrocyte-D122\|Adult / Lineage, Cell type, age group and donor	COL5A1 AOX1 ALDH1L1 PDE10A ARL4D RIMBP2 CDH13	5.45e-07	148	144	7	81a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LIN28B MACROH2A1 SGO1 F13A1 TIAM1 ATG3 MKI67	1.33e-06	169	144	7	4db49b7eaea34e6558ee73b01e76315e99cc880b
ToppCell	facs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MSRB1 ITGAL HPSE F13A1 NADK PYGL TPD52	1.33e-06	169	144	7	907e4c7d0df6dd46664d69834251aebca8e1dd1e
ToppCell	facs-Lung-24m-Hematologic-myeloid-classical_monocyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MSRB1 ITGAL HPSE F13A1 NADK PYGL TPD52	1.49e-06	172	144	7	f557ec1b4d08b42559da02dd1f2387283c6380a2
ToppCell	COVID-19-kidney-Epi_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	COL5A1 DCHS2 CYP3A5 CFAP54 C3 FRG2B VCAM1	1.95e-06	179	144	7	e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JCAD DCHS2 CYP3A5 GRIN2A ITPRID1 PCDH17 CDH13	2.18e-06	182	144	7	a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCell	droplet-Lung-LUNG-1m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF2BP2 MSRB1 NCOA4 ITGAL PITPNA PYGL TPD52	2.42e-06	185	144	7	53a5218c1e6eb12daccde3d6e02f337e2586d74c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 CFAP54 RIMBP2 RASAL1 TPD52 CCSER1	3.10e-06	192	144	7	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)\|356C / Donor, Lineage, Cell class and subclass (all cells)	JCAD C1QTNF9B PDE10A PCDH17 KL VCAM1 NOVA2	3.32e-06	194	144	7	2e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	JCAD C1QTNF9B PDE10A PCDH17 KL VCAM1 NOVA2	3.32e-06	194	144	7	b6b5b0ab506b05a005ba8a05a3c7f4c725ba9200
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C CA2 TPD52 CCSER1	3.43e-06	195	144	7	f08e41706680881ebd0afcd08a02f8ac0089f04e
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-41\|World / Primary Cells by Cluster	IRF2BP2 RTN4 AKAP9 KCNAB1 KIF5C TPD52 CCSER1	3.55e-06	196	144	7	dee0984cd63a1a2fdebb4421af48ab566a5b684e
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C CA2 TPD52 CCSER1	3.67e-06	197	144	7	22b26bac3a99b20c73bfa6e6f81026d064eaa9e8
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_DC1\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	NEXMIF LGALS2 ATG3 MKI67 VARS1 VCAM1 CCSER1	3.67e-06	197	144	7	9a3d0b7f4788487d024d56bc776a2fd1149f50d5
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C CA2 TPD52 CCSER1	3.67e-06	197	144	7	2f91b3870a7058168093a143110954c07588cfe9
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CNST HPSE LRRC8D ITGB3 F13A1 PRDX6 CFAP54	3.92e-06	199	144	7	b68648b4559e452656dc9e6a0974233e842f5e0d
ToppCell	LPS_IL1RA-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CNST HPSE ITGB3 F13A1 PRDX6 RECQL5 MKI67	4.06e-06	200	144	7	326cae37cacd94b423a6ac8873ea56c5abaf0a0b
ToppCell	background-Hepatocytes\|background / Sample and Cell Type and Tumor Cluster (all cells)	CYP2A6 CYP3A5 AOX1 ALDH1L1 SLC2A2 PRDX6 C3	4.06e-06	200	144	7	787d35b5c2f2ad967ae14e99496a0299ac7e72fd
ToppCell	COVID_non-vent-Myeloid-Monocytic-CD14+_Monocyte\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	MSRB1 MACROH2A1 SIRPB1 NCOA4 F13A1 LGALS2 PYGL	4.06e-06	200	144	7	465ed50e0b92bb8c27ffe56d816f063a45b52be9
ToppCell	COVID_vent-Lymphocytic-T_cell-Gamma_Delta_T_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	COL5A1 ZNF555 LRRC9 HFM1 RIMBP2 KIF5C	4.55e-06	132	144	6	dbc0a332fd8f63ebdcf9716e45d7f46f26509349
ToppCell	facs-Brain_Myeloid-Cerebellum_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSRB1 ITGAL HPSE F13A1 SLCO4C1 CIITA	9.85e-06	151	144	6	3105b8c0c401faa92e1ab8223d435b21ed45c5b7
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Platelets-Platelets\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GRIN2A HPSE F13A1 PRDX6 RECQL5 MKI67	1.02e-05	152	144	6	aff7d1127ef72be489477611c4decc53cc7632e3
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Platelets\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GRIN2A HPSE F13A1 PRDX6 RECQL5 MKI67	1.02e-05	152	144	6	0a99c91165e4d82fb8825fbdf3071c9a5445669d
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAL F13A1 CIITA MKI67 C2 C3	1.06e-05	153	144	6	0ef7c45cdd854c79e527006034029767f8e108b2
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A1 GRIN2A FREM2 KL KCNAB1 CCSER1	1.27e-05	158	144	6	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A1 GRIN2A FREM2 KL KCNAB1 CCSER1	1.27e-05	158	144	6	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	facs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSRB1 ITGAL HPSE F13A1 CIITA C3	1.37e-05	160	144	6	1f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR MCM6 SGO1 MKI67 CCDC15 SF3A2	1.63e-05	165	144	6	88681101d7cf60b99b8ace5d8c0944323b937306
ToppCell	droplet-Spleen-SPLEEN-1m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSRB1 F13A1 NADK PYGL C3 DEPDC7	1.80e-05	168	144	6	f3b7a7df54988de77dcc7066e2fc1feb9c280b13
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MSRB1 ITGAL F13A1 PYGL C3 TPD52	1.87e-05	169	144	6	70c841a7b1e3f665105d715a6d72762c80ce5de2
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MSRB1 ITGAL F13A1 PYGL C3 TPD52	1.87e-05	169	144	6	15d5758d94a14a909d1d0c8bba9ce497a33d1512
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MSRB1 ITGAL F13A1 PYGL C3 TPD52	1.87e-05	169	144	6	c6750c45c44be68aea39e918ba97c6f875ccea34
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MSRB1 ITGAL F13A1 PYGL C3 TPD52	1.87e-05	169	144	6	1077fbca61bd0c1f9706aeb0552b77362127f261
ToppCell	droplet-Lung-21m-Hematologic-myeloid\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MSRB1 ITGAL F13A1 NADK PYGL TPD52	1.99e-05	171	144	6	22ad6de44e1d3f72a3d78d46fd26a5743a4f84a5
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MSRB1 ITGAL F13A1 NADK PYGL TPD52	2.06e-05	172	144	6	e72966ced5f2ee9e24ce9fd820d99a69a482a607
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MSRB1 HPSE F13A1 NADK C3 TPD52	2.06e-05	172	144	6	a53c906539557594ef10368bc29aec4af063fd37
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MSRB1 ITGAL F13A1 NADK PYGL TPD52	2.06e-05	172	144	6	83730ea3b240b8e2f2a9fb6c34dd1408050867ff
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LGALS2 FREM2 C2 C3 KIF5C MYBPC1	2.13e-05	173	144	6	30d67738633493d47f06ae452424382f069b6c0a
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MSRB1 HPSE F13A1 NADK C3 TPD52	2.13e-05	173	144	6	9acad7ec70f713fe3db6cef7bbe3b183bf16ae67
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	JCAD MUC19 PDLIM5 PCDH17 KL NOVA2	2.13e-05	173	144	6	3a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Megakaryocyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LIN28B CNST HPSE ITGB3 F13A1 CA2	2.27e-05	175	144	6	b85279b9efd72d7074c4226d50ce139a38c0e1c1
ToppCell	droplet-Lung-1m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MSRB1 HPSE F13A1 NADK C3 TPD52	2.35e-05	176	144	6	8f9d2a763b79cafe26dcbf3dba980d473a0b9873
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	PPP1R9A AOX1 C3 RIMBP2 RASAL1 CCSER1	2.35e-05	176	144	6	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	droplet-Lung-1m-Hematologic-myeloid-classical_monocyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MSRB1 HPSE F13A1 NADK C3 TPD52	2.35e-05	176	144	6	3b5d12d5c22e32fbe80c3716ff14a7ae5769c165
ToppCell	tumor_Lung-Endothelial_cells-EPCs\|tumor_Lung / Location, Cell class and cell subclass	JCAD PCDHA10 PDE10A PCDH17 KL NOVA2	2.42e-05	177	144	6	f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CNST NCOA4 ITGB3 F13A1 PYGL CA2	2.50e-05	178	144	6	2c581a338bf33dbd2be9abe87d0a84f97dfb546f
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VIT NCOA4 LGALS2 FREM2 C2 C3	2.50e-05	178	144	6	bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VIT NCOA4 LGALS2 FREM2 C2 C3	2.50e-05	178	144	6	c413861148129be1ee94f2ceb5999840217eebe5
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CNST NCOA4 ITGB3 F13A1 PYGL CA2	2.50e-05	178	144	6	5caeffb70cbb868586bd260b44ccd3751bbfa615
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DCHS2 CYP3A5 CFAP54 FRG2B HYDIN VCAM1	2.50e-05	178	144	6	544379f5a6145429762258d426b876bb36c112f5
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Hematopoietic-Megakaryocytic\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CNST NCOA4 ITGB3 F13A1 PYGL CA2	2.50e-05	178	144	6	afc3220e2319cb38d59307db1b793a3915e1d5c4
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Hematopoietic\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CNST NCOA4 ITGB3 F13A1 PYGL CA2	2.50e-05	178	144	6	4ff23a0bb20c4373db14bfaad18b5fa5c7c78e76
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MSRB1 HPSE F13A1 PITPNA C3 TPD52	2.58e-05	179	144	6	66afd54428e6dcadc3e341faecfde42be4fb5905
ToppCell	droplet-Lung-1m-Hematologic-myeloid\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MSRB1 ITGAL PITPNA NADK PYGL TPD52	2.58e-05	179	144	6	6d2458a887047b5c20389f08345ff5aac7c683e6
ToppCell	wk_15-18-Epithelial-PNS-KCNIP4+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TBX22 NEXMIF MYT1 PCDHAC1 PCDHA10 RIMBP2	2.58e-05	179	144	6	e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCell	Control-Endothelial_cells-Capillary_endothelial_cells\|Control / group, cell type (main and fine annotations)	JCAD CYP3A5 ITPRID1 PCDH17 CDH13 NOVA2	2.66e-05	180	144	6	b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	JCAD CYP3A5 ITPRID1 PCDH17 CDH13 NOVA2	2.75e-05	181	144	6	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VIT STPG2 LRRC9 CFAP52 C3 HYDIN	3.01e-05	184	144	6	264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VIT STPG2 LRRC9 CFAP52 C3 HYDIN	3.01e-05	184	144	6	d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VIT STPG2 LRRC9 CFAP52 C3 HYDIN	3.01e-05	184	144	6	22010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C TPD52 CCSER1	3.01e-05	184	144	6	fa4915b0498f3069fd5ef497286445528f75187e
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C TPD52 CCSER1	3.20e-05	186	144	6	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C TPD52 CCSER1	3.30e-05	187	144	6	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C TPD52 CCSER1	3.50e-05	189	144	6	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	mild-Others\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MSRB1 NCOA4 ITGB3 F13A1 PYGL CA2	3.60e-05	190	144	6	782dc1b612ac1faad7cc2781bfda92a079830d38
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C TPD52 CCSER1	3.60e-05	190	144	6	c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCell	pdx-Tumor_cells-T8\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CYP3A5 ITGAL SLC2A2 FER1L6 ACOT12 C3	3.60e-05	190	144	6	b05db0de9b6ae01dd30074453f7de44f7397631e
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NEXMIF PDE10A LGALS2 CDKL5 NRXN2 C2	3.60e-05	190	144	6	f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JCAD DCHS2 CYP3A5 PCDH17 CDH13 NOVA2	3.60e-05	190	144	6	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NEXMIF PDE10A LGALS2 CDKL5 NRXN2 C2	3.60e-05	190	144	6	a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCell	3'_v3-Lung-Myeloid_Dendritic-DC2\|Lung / Manually curated celltypes from each tissue	LGALS2 CIITA C3 RASAL1 MYBPC1 CCSER1	3.60e-05	190	144	6	468525c05e38158a3b8a445882b2d63dfb1d2c63
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NEXMIF PDE10A LGALS2 CDKL5 NRXN2 C2	3.60e-05	190	144	6	57c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	JCAD CYP3A5 GRIN2A PCDH17 CDH13 NOVA2	3.71e-05	191	144	6	f229abf69a1217194f74b0502486907e07dba989
ToppCell	mild-Others-Megakaryocytes\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MSRB1 NCOA4 ITGB3 F13A1 PYGL CA2	3.71e-05	191	144	6	0b36223bd7f5758cc37194da6cc252f613bc3c97
ToppCell	10x5'v1-week_14-16-Hematopoietic-MK-MK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CNST HPSE ITGB3 F13A1 PDLIM5 CA2	3.82e-05	192	144	6	b877d14be9d04ab0010e340909e3a23de92613db
ToppCell	Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|World / Lineage, Cell type, age group and donor	JCAD CYP3A5 GRIN2A PCDH17 CDH13 NOVA2	3.82e-05	192	144	6	1e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	TRPM7 HSDL2 PPP1R9A PDLIM5 CDH13 CCSER1	3.82e-05	192	144	6	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	18-Distal-Epithelial-Secretory_progenitor\|Distal / Age, Tissue, Lineage and Cell class	CYP2A6 CYP2A7 CYP2A13 C2 C3 TPD52	3.82e-05	192	144	6	9fae988ecd2ef1231bfd42a678a4903517694cbe
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD UBR4 PCDH17 CSDE1 PDIA5 HYDIN	3.82e-05	192	144	6	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	(6)_Endothelial-C_(Capillary_Aerocyte_)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	JCAD CYP3A5 PRDX6 PCDH17 KL NOVA2	3.93e-05	193	144	6	f7f2dc6aff02d096a282835094d26d12b3b73e61
ToppCell	10x3'2.3-week_12-13-Hematopoietic-MK-MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CNST RTN4 HPSE ITGB3 PDLIM5 CA2	3.93e-05	193	144	6	3d4411b3c1cb160dec5db29f0c126d8827dfe185
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C CA2 TPD52	3.93e-05	193	144	6	4b8202fcfe639a73f69a13f48fc3601ade256346
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C TPD52 CCSER1	4.05e-05	194	144	6	c5ef4ff73b4e51530656002e3a2fb7264cdf533d
ToppCell	Control-Classical_Monocyte\|Control / Disease condition and Cell class	MSRB1 HPSE FAM200B F13A1 LGALS2 PYGL	4.05e-05	194	144	6	9e33e1b54b4114f9e6981819834bb796ed7192b5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PPP1R9A STPG2 FREM2 SLCO4C1 HYDIN CCSER1	4.05e-05	194	144	6	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C CA2 TPD52	4.05e-05	194	144	6	acd5ba9a097595d4caab4f05440531c65a4aa7bc
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C TPD52 CCSER1	4.05e-05	194	144	6	b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCell	PCW_07-8.5-Epithelial\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C TPD52 CCSER1	4.05e-05	194	144	6	f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 CFAP54 KIF5C TPD52 CCSER1	4.05e-05	194	144	6	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C TPD52 CCSER1	4.05e-05	194	144	6	c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	AOX1 MUC19 PDE10A STPG2 KCNB1 PYGL	4.16e-05	195	144	6	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PPP1R9A FREM2 RIMBP2 KIF5C TPD52 CCSER1	4.16e-05	195	144	6	98dd3b7d5ef587825dac052dea4d4ff883f6d4d6
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	AOX1 MUC19 PDE10A STPG2 KCNB1 PYGL	4.16e-05	195	144	6	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF2BP2 SLC2A2 AKAP9 KCNB1 ANKRD11 PCM1	4.16e-05	195	144	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF2BP2 SLC2A2 AKAP9 KCNB1 ANKRD11 PCM1	4.16e-05	195	144	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PPP1R9A FREM2 SLCO4C1 C2 C3 CA2	4.28e-05	196	144	6	7e5addaa844e66f8160e05858c341866a80aed23
Drug	trans-3'-hydroxycotinine	CYP2A6 CYP2A13 CYP3A5 AOX1 HPSE KL	2.33e-08	29	143	6	CID000000414
Drug	sulfur	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 AOX1 DBT AKAP9 C2 C3 CA2	1.44e-07	219	143	11	CID000000402
Drug	2'-methoxyacetophenone	CYP2A6 CYP2A7 CYP2A13	2.43e-07	3	143	3	CID000068481
Drug	nitro-L	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 PRDX6	5.46e-07	48	143	6	CID000006849
Drug	BP-9,10-oxide	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	6.58e-07	27	143	5	CID000037456
Drug	Brn 4136738	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	6.58e-07	27	143	5	CID000050331
Drug	C14845	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	6.58e-07	27	143	5	CID011954064
Drug	9-OH-BaP-4,5-oxide	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	7.97e-07	28	143	5	CID000115064
Drug	19-hydroxytestosterone	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	1.14e-06	30	143	5	CID000150968
Drug	11-H-14,15-EETA	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	1.14e-06	30	143	5	CID011954058
Drug	N-nitrosomethylaniline	CYP2A6 CYP2A7 CYP2A13 CYP3A5	1.42e-06	14	143	4	CID000011957
Drug	BP-7,8-oxide	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	1.60e-06	32	143	5	CID000037455
Drug	12(13)-EpOME	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	2.19e-06	34	143	5	CID000001416
Drug	TCEO	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	2.19e-06	34	143	5	CID000028167
Drug	AC1O5XSP	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	2.19e-06	34	143	5	CID006442739
Drug	AC1L1CJI	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	2.54e-06	35	143	5	CID000001929
Drug	S)-cotinine	CYP2A6 CYP2A7 CYP2A13 CYP3A5 AOX1 ITGB3 VCAM1	2.67e-06	97	143	7	CID000000408
Drug	chlorzoxazone	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 C2	2.80e-06	63	143	6	CID000002733
Drug	15-H-11,12-EETA	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	2.94e-06	36	143	5	CID011954042
Drug	AC1L3NGJ	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	2.94e-06	36	143	5	CID000092121
Drug	5,6-epoxyeicosatrienoic acid	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 CA2	4.39e-06	68	143	6	CID000001778
Drug	11,14,15-THET	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	4.42e-06	39	143	5	CID006439531
Drug	8(9)-EET	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 CA2	4.78e-06	69	143	6	CID000001901
Drug	AC1L196J	CYP2A6 CYP2A13 AOX1	4.79e-06	6	143	3	CID000000415
Drug	1h1q	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 AOX1	5.21e-06	70	143	6	CID000001540
Drug	11,12,15-trihydroxyeicosatrienoic acid	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	6.43e-06	42	143	5	CID006439610
Drug	ethyl iodoacetate	CYP2A6 CYP3A5 AOX1 HPSE KL	6.43e-06	42	143	5	CID000012183
Drug	3C etc	CYP2A6 CYP2D7 CYP3A5 AOX1	6.68e-06	20	143	4	CID000164045
Drug	7-hydroxycoumarin	CYP2A6 CYP2A7 CYP2A13 CYP3A5 HPSE KL	7.79e-06	75	143	6	CID005281426
Drug	polybrominated biphenyl	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	8.12e-06	44	143	5	CID000042948
Drug	2-sulfamoylacetylphenol	CYP2D7 CYP3A5 AOX1	8.34e-06	7	143	3	CID000194588
Drug	naphthalene-1,2-dihydrodiol	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	9.09e-06	45	143	5	CID000000362
Drug	C20H32O4	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 PRDX6	9.79e-06	78	143	6	CID000001440
Drug	NSC35549	CYP2A6 CYP2A7 CYP2A13 CYP2D7	9.99e-06	22	143	4	CID000411697
Drug	C14802	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	1.13e-05	47	143	5	CID011954053
Drug	C14800	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	1.26e-05	48	143	5	CID011954051
Drug	2bq7	CYP2A6 MYH4 CYP2D7 CYP3A5 PRDX6 TAF15 MYBPC1	1.29e-05	123	143	7	CID006540267
Drug	19-HETE	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	1.39e-05	49	143	5	CID006439528
Drug	bromobenzene-3,4-oxide	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	1.39e-05	49	143	5	CID000108121
Drug	bromobenzene-2,3-oxide	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	1.54e-05	50	143	5	CID003036760
Drug	6-hydroxymelatonin	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	1.54e-05	50	143	5	CID000001864
Drug	1,1-dichloroethylene epoxide	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	1.54e-05	50	143	5	CID000119521
Drug	naphthalene epoxide	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	1.70e-05	51	143	5	CID000108063
Drug	methyl tert-butyl ether	CYP2A6 CYP3A5 NCOA4 AKAP9	1.70e-05	25	143	4	CID000015413
Drug	carbon monoxide	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 AOX1 KL GUCY2C C2	1.71e-05	233	143	9	CID000000281
Drug	trichloroethylene	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 C2	1.96e-05	88	143	6	CID000006575
Drug	mephenytoin	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 C2	1.96e-05	88	143	6	CID000004060
Drug	3-hydroxy-3-methyloxindole	CYP2A6 CYP3A5 AOX1	1.98e-05	9	143	3	CID000151066
Drug	fenthion sulfoxide	CYP3A5 AOX1 DBT	1.98e-05	9	143	3	CID000019577
Drug	8-HQG	CYP3A5 HPSE KL	1.98e-05	9	143	3	CID000084592
Drug	9-hydroxybenzo(a)pyrene	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	2.05e-05	53	143	5	CID000028598
Drug	dichloroacetaldehyde	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	2.25e-05	54	143	5	CID000006576
Drug	chloroacetyl chloride	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	2.46e-05	55	143	5	CID000006577
Drug	2-naphthol	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 C2	2.69e-05	93	143	6	CID000008663
Drug	orphenadrine	CYP2A6 CYP2A13 CYP2D7 CYP3A5 GRIN2A	2.69e-05	56	143	5	CID000004601
Drug	encainide	CYP2A6 CYP2D7 CYP3A5 MYBPC1	2.72e-05	28	143	4	CID000048040
Drug	tioconazole	CYP2A6 CYP3A5 YARS2	2.82e-05	10	143	3	CID000005482
Drug	alpha-hydroxyalprazolam	CYP3A5 HPSE KL	2.82e-05	10	143	3	CID000162244
Drug	1-methylnaphthalene	AOX1 DBT KL	2.82e-05	10	143	3	CID000007002
Drug	NADP(H	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 AOX1 ALDH1L1 DBT PRDX6 MTHFD1 NADK KCNAB1 PYGL	2.92e-05	527	143	13	CID000000930
Drug	1,2-dihydroxynaphthalene	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	2.93e-05	57	143	5	CID000011318
Drug	bromoacetaldehyde	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	3.19e-05	58	143	5	CID000105131
Drug	Chlorhexidine [55-56-1]; Down 200; 8uM; PC3; HG-U133A	EMC1 NVL DBT DNAJC7 PDLIM5 RECQL5 PITPNA NADK	3.32e-05	195	143	8	1942_DN
Drug	Canavanine sulfate monohydrate (L,+) [206996-57-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A	EMC1 SMCHD1 U2SURP DBT LRRC8D RCBTB1 CA2 TPD52	3.45e-05	196	143	8	4782_DN
Drug	tolbutamide	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 SLC2A2 PYGL C2	3.70e-05	198	143	8	CID000005505
Drug	Canrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; PC3; HT_HG-U133A	COL5A1 BCORL1 DBT ARL4D AKAP9 RECQL5 NADK SF3A2	3.70e-05	198	143	8	2065_UP
Drug	1,1-dichloroethylene	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	3.77e-05	60	143	5	CID000006366
Drug	sphondin	CYP2A6 CYP2D7 CYP3A5	3.86e-05	11	143	3	CID000108104
Drug	9-benzyladenine	CYP2D7 CYP3A5 CA2	3.86e-05	11	143	3	CID000020262
Drug	Nsc70535	CYP2A6 CYP3A5	3.92e-05	2	143	2	CID006847048
Drug	propargyl ether	CYP2A6 CYP2A13	3.92e-05	2	143	2	ctd:C531209
Drug	Hempa	CYP2A6 CYP2A13	3.92e-05	2	143	2	ctd:D006492
Drug	3-Hfbt	DBT C2	3.92e-05	2	143	2	CID005489052
Drug	nicotelline	CYP2A6 CYP3A5	3.92e-05	2	143	2	CID000068123
Drug	7-aminocoumarin	CYP2A6 CYP3A5	3.92e-05	2	143	2	CID000189055
Drug	nicotine imine	CYP2A6 CYP2A13	3.92e-05	2	143	2	ctd:C034629
Drug	alpha-nicotyrine	CYP2A6 CYP2A13	3.92e-05	2	143	2	ctd:C008615
Drug	4-hydroxy-4-(3-pyridyl)butanal	CYP2A6 CYP3A5	3.92e-05	2	143	2	CID000188122
Drug	2,3'-bipyridyl	CYP2A6 CYP3A5	3.92e-05	2	143	2	CID000011389
Drug	thioisatin	DBT C2	3.92e-05	2	143	2	CID000097303
Drug	BRL 44385	CYP3A5 AOX1	3.92e-05	2	143	2	CID003082700
Drug	N-nitrosoguvacoline	CYP2A6 CYP2A13	3.92e-05	2	143	2	ctd:C036676
Drug	nicotyrine	CYP2A6 CYP3A5	3.92e-05	2	143	2	CID000010249
Drug	BP-4,5-oxide	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	4.09e-05	61	143	5	CID000037786
Drug	zonisamide	CYP2A6 CYP2D7 CYP3A5 AOX1 CA2	4.42e-05	62	143	5	CID000005734
Drug	bromide	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 PRDX6 NRXN2 C3 CA2	4.98e-05	267	143	9	CID000000259
Drug	tame	CYP2A6 CYP3A5 NCOA4	5.12e-05	12	143	3	CID000061247
Drug	16 alpha-hydroxytestosterone	CYP2A6 CYP2D7 CYP3A5	5.12e-05	12	143	3	CID000065545
Drug	nicotine-N'-oxide	CYP2A6 CYP3A5 AOX1	5.12e-05	12	143	3	CID000000409
Drug	midazolam	CYP2A6 CYP2A13 CYP2D7 CYP3A5 C2 NOVA2	5.93e-05	107	143	6	CID000004192
Drug	trichloroacetic acid	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 C2	5.93e-05	107	143	6	CID000006421
Drug	piperonyl butoxide	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	6.43e-05	67	143	5	CID000005794
Drug	propoxyphene	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	6.43e-05	67	143	5	CID000010100
Drug	3-methyloxindole	CYP2A6 CYP3A5 AOX1	6.63e-05	13	143	3	CID000150923
Drug	AC1L18GM	CYP2D7 CYP3A5 AOX1	6.63e-05	13	143	3	CID000000092
Drug	NSC9700	CYP2A6 CYP2A7 MYH4 CYP2A13 CYP2D7 CYP3A5 NCOA4 HPSE PDLIM5 KL GUCY2C C2 VCAM1	7.49e-05	578	143	13	CID000005408
Drug	hexamethylphosphoramide	CYP2A6 CYP2A7 CYP2A13 CYP3A5	7.52e-05	36	143	4	CID000012679
Drug	4-bromophenol	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	7.94e-05	70	143	5	CID000007808
Drug	proadifen hydrochloride	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5 AOX1	8.44e-05	114	143	6	CID000004910
Drug	1,2-dibromoethane	CYP2A6 CYP2A7 CYP2A13 CYP2D7 CYP3A5	8.50e-05	71	143	5	CID000007839
Disease	Colorectal Carcinoma	TBX22 CYP2A6 TRPM7 RTN4 GRIN2A ALDH1L1 ERI2 ITPRID1 CDKL5 KL AKAP9 TIAM1 GUCY2C MKI67	6.75e-06	702	140	14	C0009402
Disease	1,5 anhydroglucitol measurement	PCDHAC1 PCDHA10 MCM6 PCDHA2	1.05e-05	29	140	4	EFO_0008009
Disease	–	ITGB3 F13A1 LGALS2	2.89e-05	13	140	3	608446
Disease	Myocardial infarction, susceptibility to	ITGB3 F13A1 LGALS2	2.89e-05	13	140	3	cv:C1832662
Disease	Schizophrenia	MSRB1 CYP3A5 RTN4 SIRPB1 GRIN2A ITGB3 PDLIM5 PRDX6 PCDH17 KCNB1 NRXN2 MTHFD1 RCBTB1 PCM1	8.31e-05	883	140	14	C0036341
Disease	interstitial cystitis (is_marker_for)	MKI67 VCAM1	2.21e-04	5	140	2	DOID:13949 (is_marker_for)
Disease	MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO	ITGB3 F13A1	3.31e-04	6	140	2	C1832662
Disease	Spina bifida aperta of cervical spine	VANGL2 MTHFD1	3.31e-04	6	140	2	C1960883
Disease	hypothyroidism	MYT1 PDE10A ITGB3 SBF1 GNA12 RPL3 CDH13	4.29e-04	284	140	7	EFO_0004705
Disease	ER membrane protein complex subunit 4 measurement	C2 C3	4.62e-04	7	140	2	EFO_0801580
Disease	neural tube defect (is_implicated_in)	VANGL2 MTHFD1	6.14e-04	8	140	2	DOID:0080074 (is_implicated_in)
Disease	7-methylguanine measurement	PPP1R9A AOX1	6.14e-04	8	140	2	EFO_0021123
Disease	Epilepsy, Cryptogenic	NEXMIF GRIN2A CDKL5 ANKRD11	6.37e-04	82	140	4	C0086237
Disease	Awakening Epilepsy	NEXMIF GRIN2A CDKL5 ANKRD11	6.37e-04	82	140	4	C0751111
Disease	Aura	NEXMIF GRIN2A CDKL5 ANKRD11	6.37e-04	82	140	4	C0236018
Disease	Autism Spectrum Disorders	ITGB3 NRXN2 ANKRD11 CA2	7.30e-04	85	140	4	C1510586
Disease	Liver carcinoma	TICRR HPSE SLC2A2 PRDX6 MKI67 PYGL CDH13 VCAM1 CA2	7.31e-04	507	140	9	C2239176
Disease	age at onset, Myopia	TIAM1 CIITA RCBTB1 HYDIN CDH13	7.63e-04	150	140	5	EFO_0004847, HP_0000545
Disease	glycogen storage disease (is_implicated_in)	SLC2A2 PYGL	7.87e-04	9	140	2	DOID:2747 (is_implicated_in)
Disease	mean fractional anisotropy measurement	STPG2 VANGL2 ANKRD11 GNA12	1.11e-03	95	140	4	EFO_0008399
Disease	myocardial infarction (is_implicated_in)	ITGB3 F13A1 LGALS2 CIITA	1.29e-03	99	140	4	DOID:5844 (is_implicated_in)
Disease	nicotine metabolite ratio	CYP2A6 CYP2A7	1.43e-03	12	140	2	EFO_0007794
Disease	cleft palate (is_implicated_in)	TBX22 MTHFD1	1.43e-03	12	140	2	DOID:674 (is_implicated_in)
Disease	systemic lupus erythematosus (is_marker_for)	MKI67 C2 VCAM1	1.45e-03	47	140	3	DOID:9074 (is_marker_for)
Disease	metabolite measurement	CYP2A6 CYP2D7 CYP3A5 DNAJC16 MCM6 ALDH1L1 FAM200B PDLIM5 RIMBP2	1.46e-03	560	140	9	EFO_0004725
Disease	monocyte count	JCAD ARID4B TRPM7 U2SURP MCM6 SIRPB1 CIITA RCBTB1 GPR156 C3 HFM1 GNA12 VARS1 VCAM1 MYBPC1	1.55e-03	1320	140	15	EFO_0005091
Disease	Epilepsy	NEXMIF GRIN2A CDKL5 ANKRD11	1.84e-03	109	140	4	C0014544
Disease	wet macular degeneration	C2 C3	1.96e-03	14	140	2	EFO_0004683
Disease	precuneus cortex volume measurement	CDH13 CCSER1	1.96e-03	14	140	2	EFO_0010326
Disease	multiple myeloma	TICRR ANKRD11 CDH13 CCSER1	2.03e-03	112	140	4	EFO_0001378
Disease	diabetic retinopathy (is_marker_for)	ITGB3 F13A1 VCAM1	2.17e-03	54	140	3	DOID:8947 (is_marker_for)
Disease	distal arthrogryposis (implicated_via_orthology)	MYH4 MYBPC1	2.25e-03	15	140	2	DOID:0050646 (implicated_via_orthology)
Disease	glucose measurement	RTN4 EFCAB13 SLC2A2 PPM1G KL PDIA5 TPD52	2.31e-03	380	140	7	EFO_0004468
Disease	immature platelet measurement	JCAD SIRPB1 TESK2 PDIA5	2.53e-03	119	140	4	EFO_0803541
Disease	pancreatitis	JCAD MYBPC1	2.57e-03	16	140	2	EFO_0000278
Disease	pulse pressure measurement	JCAD TRPM7 MYT1 EFCAB13 PCDHAC1 PCDHA10 PCDHA2 GPATCH8 SRFBP1 PDLIM5 ANKRD11 NADK HYDIN CDH13 PCM1	2.58e-03	1392	140	15	EFO_0005763
Disease	FEV change measurement, response to bronchodilator	PITPNA CDH13 PCM1	2.67e-03	58	140	3	EFO_0005921, GO_0097366
Disease	urate measurement, bone density	COL5A1 AHCTF1 PCDH17 USP14 ANKRD11 C2 CDH13 NUP153 RASAL1	2.86e-03	619	140	9	EFO_0003923, EFO_0004531
Disease	low density lipoprotein cholesterol measurement, body fat percentage	EFCAB13 MCM6	2.90e-03	17	140	2	EFO_0004611, EFO_0007800
Disease	lupus nephritis (is_marker_for)	C3 VCAM1	2.90e-03	17	140	2	DOID:0080162 (is_marker_for)
Disease	SARS-CoV-2 antibody measurement, response to COVID-19 vaccine	COL5A1 CDH13 MYBPC1	3.22e-03	62	140	3	EFO_0803360, EFO_0803362
Disease	Age-related macular degeneration	C2 C3	3.25e-03	18	140	2	cv:C0242383
Disease	white matter integrity	STPG2 VANGL2 C2 GNA12	3.48e-03	130	140	4	EFO_0004641
Disease	X-11470 measurement	C2 VARS1	3.63e-03	19	140	2	EFO_0021241
Disease	emphysema pattern measurement	JCAD CYP2A6	3.63e-03	19	140	2	EFO_0005850
Disease	glomerulonephritis (is_marker_for)	ITGB3 VCAM1	3.63e-03	19	140	2	DOID:2921 (is_marker_for)
Disease	caffeine metabolite measurement	CYP2A6 CYP2A7	3.63e-03	19	140	2	EFO_0007872
Disease	Liver Cirrhosis, Experimental	COL5A1 RTN4 U2SURP ALDH1L1 ITGAL HPSE ITGB3 LGALS2 MKI67 DEPDC7	3.93e-03	774	140	10	C0023893
Disease	radiation-induced disorder	DCHS2 PDE10A PDLIM5	4.01e-03	67	140	3	EFO_0009565
Disease	chronic kidney disease (is_marker_for)	KL VCAM1	4.02e-03	20	140	2	DOID:784 (is_marker_for)
Disease	skin pigmentation measurement	SBF1 ANKRD11 RIMBP2 HYDIN	4.19e-03	137	140	4	EFO_0007009
Disease	Infiltrating duct carcinoma of female breast	TRPM7 TESK2	4.42e-03	21	140	2	C3165106
Disease	cardiomyopathy (implicated_via_orthology)	MYH4 PDLIM5 COA6	4.72e-03	71	140	3	DOID:0050700 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
TKKVPFFKLSEEFVD	VANGL2	491	Q9ULK5
SFKDGKFTSVPRKDV	ARID4B	216	Q4LE39
TIFDDKSADKLKTIP	FAM200B	181	P0CF97
VKEAKDPGSDISAFK	ERI2	486	A8K979
GEFTLTTLKKEAKFE	AKAP2	166	Q9Y2D5
ESESATDSFPKKIKG	AKAP9	2931	Q99996
LDDLTKAEKFKESPS	CFAP54	2486	Q96N23
LKFKEFVQSVPTKGF	ARL4D	41	P49703
KKEKAFPGIISEDFS	ANKRD11	1086	Q6UB99
KDTKFRDFFLPKGTE	CYP2A6	376	P11509
AEEKFTIEPFKAKSL	CIITA	911	P33076
DPFVESTKKFLKFGF	CYP3A5	201	P20815
FKKITVVPSAKDFID	GTPBP4	6	Q9BZE4
ADDKKLKSIAFPSIG	MACROH2A1	301	O75367
EKKAKSSFRDFIPVV	BCORL1	1206	Q5H9F3
DFPGKKLVLSSEKTV	C3	61	P01024
VAFSTFVAKPVGKEK	ACOT12	106	Q8WYK0
ELPFGDKDTKSKVTL	CSDE1	296	O75534
KPTAKTEGLSTFLEK	CCSER1	831	Q9C0I3
KVFEAVPTKVFGKDK	DEPDC7	106	Q96QD5
LVTFPKEERKSVSGK	ANKRD17	1656	O75179
PKFTKKEFQATVEEG	CDH13	361	P55290
KSRGFSLEPKEFDKL	ARMCX5	301	Q6P1M9
SKFKETGVITPEEFV	ATG3	26	Q9NT62
FEEGSKTSPKLFAEE	AOX1	191	Q06278
KKEFDSPETADLKFR	RCBTB1	361	Q8NDN9
KEEPAGLATRFAFKK	RASAL1	576	O95294
DKDTGKPKGEATVSF	TAF15	276	Q92804
TIKAEFNKFKPGAVE	RBM46	251	Q8TBY0
KAFEFKVLAKDSGAP	PCDH17	546	O14917
AEEDPAKFKSIKTGR	PITPNA	156	Q00169
PDFKKIETTLAKIFG	GUCY2C	736	P25092
DKTPSVKKDSFFLDL	NVL	176	O15381
IDKSDFITFGKKEET	PCDHA2	906	Q9Y5H9
KNPEVSVFSKDLKFD	LRRC9	646	Q6ZRR7
VFTGKDKTEPIKGFQ	DBT	246	P11182
QFKPKISKESEDFIV	MCM6	581	Q14566
LFFVDTGSKEKGLTK	NOP53	86	Q9NZM5
GVFDEPSTSKETKLK	MAP10	581	Q9P2G4
SFKVKDEVFVPFTKP	ITPRID1	276	Q6ZRS4
DTKATVVGKPEKTFF	HDHD2	171	Q9H0R4
FSVAGKDKSPKKASE	KCNAB1	26	Q14722
AGLRFEVVPSKFKEK	ASMTL	31	O95671
EKAVISPGFDVFAKK	C2	536	P06681
LESKFFEQKDVETKP	JCAD	1196	Q9P266
IKFGETKFSVTEPKE	FREM2	2251	Q5SZK8
SLKEGEPVEFTFKKS	LIN28B	76	Q6ZN17
EPVEFTFKKSSKGLE	LIN28B	81	Q6ZN17
TKLLTDVGPAKDKFS	CFAP52	236	Q8N1V2
SFSFAKKAPVKLESI	GPATCH8	301	Q9UKJ3
PAIASDESFGAVKKK	NADK	146	O95544
KPFIKTGFSVSVEKS	PCM1	1221	Q15154
SSGDSDKKKPLFSFE	MUC19	146	Q7Z5P9
DKKKPLFSFEFGATG	MUC19	151	Q7Z5P9
EGKPVFKKTKEIRFS	PDE10A	311	Q9Y233
FFKVPETKGKSFEEI	SLC2A2	481	P11168
PTKGKEEFVATFKGN	NRXN2	281	Q9P2S2
SFTKENSSKIPKKGF	DNAJC16	586	Q9Y2G8
KAEFKKETFDVTLEP	F13A1	566	P00488
VSKKVESTGAVPEFK	HSDL2	281	Q6YN16
VTFESDKFKVKLPDG	LGALS2	86	P05162
TGDSKSIKAFKESPK	MKI67	2516	P46013
ESLEGQTFFSKKDKP	PDLIM5	571	Q96HC4
IKLSKSKDFYPGTTE	NOVA2	66	Q9UNW9
GTKTDFLIFDPKKES	HPSE	96	Q9Y251
PKTVDEKAFFDVKTT	SBF1	1826	O95248
KSGQLTVKEPKFLDF	DCHS2	2191	Q6V1P9
IDKSDFITFGKKEET	PCDHA10	906	Q9Y5I2
KSQSVDLKEFGFTPK	HFM1	1201	A2PYH4
IDKSDFITFGKKEET	PCDHAC1	921	Q9H158
KPENGSRETSEKFKL	NCOA4	316	Q13772
QISFTEKGSDEKKPF	FRG2B	26	Q96QU4
QISFTEKGSDEKKPF	FRG2C	26	A6NGY1
QISFTEKGSDEKKPF	FRG2	26	Q64ET8
KFKVKFSPLDIGDFE	HYDIN	3906	Q4G0P3
FAEKDEDDTKFKSIP	KCNB1	351	Q14721
KDTKFRDFFLPKGTE	CYP2A13	376	Q16696
DSSVFIKPEKLFDVK	CPLANE1	2331	Q9H799
KPEFRFKGQSTKSDS	CPLANE1	2656	Q9H799
KDTKFRDFFLPKGTE	CYP2A7	376	P20853
LSKFPSSDVPIKFDK	C1QTNF9B	211	B2RNN3
KTVSIKKHFPDFRGD	GNA12	306	Q03113
FPEDFSILTTVKAKK	COL5A1	96	P20908
SKPEFKKITELTEAG	EFCAB13	561	Q8IY85
PEKKKSNLAESFGSE	CCDC38	301	Q502W7
VGEAFTILSDPKKKT	DNAJC7	431	Q99615
KEKSFTIKPVGFKDS	ITGB3	436	P05106
KDSSFSPGKEEKISD	GPR156	461	Q8NFN8
SPGKEEKISDSKDFS	GPR156	466	Q8NFN8
DFTESEKKFIKGTAD	KL	351	Q9UEF7
PRKTESELEKSFAEK	CCDC196	151	A0A1B0GTZ2
AADDSKLEVFTTPKK	AHCTF1	1246	Q8WYP5
EFSPGSKKLVVATEK	EMC1	46	Q8N766
LSPKEAKSKTEFDFN	CDKL5	406	O76039
FESKFKKEPALTAGR	IRF2BP2	321	Q7Z5L9
STVESAKRFLEKFKP	MTHFD1	286	P11586
GIAEDPKVFLSSKSK	CNST	416	Q6PJW8
KTGFKFSAEKPVIEV	LRRC8D	256	Q7L1W4
VTFKSIVAFLKDPKG	PDIA5	126	Q14554
IFSSSLKFVPKGKET	MSRB1	96	Q9NZV6
FSKSKELTGKVEAEF	FER1L6	1756	Q2WGJ9
PKVEEKISFSDDFSK	RTN4	926	Q9NQC3
KAAKEFGVSPDKISL	VARS1	766	P26640
EKKEAFVEFSTLPAG	RIMBP2	471	O15034
KDIKLTAFPSESVKE	VCAM1	601	P19320
GFVFITFKEEEPVKK	HNRNPAB	196	Q99729
FSVKEGKPEKFSFGL	SMCHD1	816	A6NHR9
GDKFIPKFKGDETVV	KIF5C	26	O60282
EKIDLKFIDTTSKFG	RPL3	361	P39023
GLFKDFFPETGTKIE	YARS2	46	Q9Y2Z4
GPDSVKVKAQDTEFK	NEXMIF	696	Q5QGS0
EEAKKLFPKGVFTKE	PRDX6	196	P30041
DKLPRVAKSKFFEDS	PPM1G	246	O15355
YTDEKETEGSKPTKT	SGO1	411	Q5FBB7
FATIAVTGEKKKEEP	MYH4	196	Q9Y623
KFASKPASEFVKILD	ITGAL	301	P20701
FKVPSREIDKAEGKF	SF3A2	181	Q15428
TEAFVEEPSKKGALK	U2SURP	521	O15042
PKVLEVEDSTDFFKS	ALDH1L1	336	O75891
SFKTVIKKKGSVFPD	CCDC15	186	Q0P6D6
IKTKGKSADFTNFDP	CA2	166	P00918
KFKEKFEAGQFEPSE	COA6	106	Q5JTJ3
LAKKEKAKGSPESSF	CYP2D7	276	A0A087X1C5
KKVFGFDSFKTPLQE	RECQL5	21	O94762
FESKGLPAELKSIFK	SLC25A25	21	Q6KCM7
VKFRKGSPDDVEFKS	SIRPB1	121	O00241
TLRSSKPKDFKTEEE	TICRR	626	Q7Z2Z1
DKSLKEVFKTFDPTA	ZC3H6	1171	P61129
YGEKIPKESKIATFT	ZNF555	61	Q8NEP9
KKEPELAAFVFKTAV	TIAM1	1286	Q13009
EKSVPGFKASKDRLT	TIGD1	206	Q96MW7
DINFEKIFKKPDSTA	SRFBP1	81	Q8NEF9
DVKFGKSIKDFPAAL	SLCO4C1	361	Q6ZQN7
LPTEGVKTFSFKETE	TBX22	241	Q9Y458
KASKRFEESKEITPG	STPG2	421	Q8N412
ESFIVLESKPKKGVT	VIT	131	Q6UXI7
FGVSSESKPEEVKKD	NUP153	961	P49790
EDVKNSPTFKSFEEK	TPD52	166	P55327
SPTFKSFEEKVENLK	TPD52	171	P55327
GKIKFFDLPSKSVIS	TESK2	411	Q96S53
PSKKKSLIDQFFGVE	USP14	236	P54578
FNEEGTTEKPSKEKL	UBR4	1181	Q5T4S7
TTEKPSKEKLQGFAA	UBR4	1186	Q5T4S7
TKVFKDFSELEPDKF	PYGL	466	P06737
PITVSYAFKKDSKGE	SF3B4	171	Q15427
KDKTSDGPKLFLTEE	TRPM7	1151	Q96QT4
SLKEGEAVEFTFKKS	LIN28A	86	Q9H9Z2
DKTKFTITGLPTDAK	MYBPC1	791	Q00872
KLSGDEVLSPKFKTS	MYT1	981	Q01538
IEEKKKSPDFNLTGS	GRIN2A	876	Q12879
EFQALKSTFDKPKSD	PPP1R9A	26	Q9ULJ8