Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbone sialoprotein binding

ANXA2 ANXA2P2

3.52e-0521192GO:0044730
GeneOntologyMolecularFunctioncalcium-dependent cysteine-type endopeptidase activity

CAPN2 CAPN8 CAPN5

1.32e-04171193GO:0004198
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH7 DNAH5 DNAH8

1.58e-04181193GO:0008569
GeneOntologyMolecularFunctionphospholipase A2 inhibitor activity

ANXA2 ANXA2P2

3.48e-0451192GO:0019834
GeneOntologyBiologicalProcessaxonemal dynein complex assembly

SPAG1 DNAH7 CFAP57 DNAH5 DNAH8

4.05e-06411215GO:0070286
GeneOntologyBiologicalProcesspositive regulation of low-density lipoprotein particle receptor binding

ANXA2 ANXA2P2

3.41e-0521212GO:1905597
GeneOntologyBiologicalProcessaxoneme assembly

SPAG1 CNTRL DNAH7 CFAP57 DNAH5 DNAH8

4.45e-051091216GO:0035082
GeneOntologyBiologicalProcesspositive regulation of receptor-mediated endocytosis involved in cholesterol transport

ANXA2 ANXA2P2

1.02e-0431212GO:1905602
GeneOntologyBiologicalProcessnegative regulation of low-density lipoprotein particle receptor catabolic process

ANXA2 ANXA2P2

1.02e-0431212GO:0032804
GeneOntologyBiologicalProcesscilium organization

SPAG1 TTC39C CNTRL DNAH7 ACTR2 NME8 TTC29 IQCB1 CFAP57 DNAH5 DNAH8

1.15e-0447612111GO:0044782
GeneOntologyBiologicalProcessintracellular transport

POLDIP3 ANXA2 ANXA2P2 SNUPN LYST ACTR2 IFNG RHOB TOMM70 LRPPRC NAPB LMX1B SGSM2 NXF5 EXOC6B NXF2 LTV1 GNAS HERC2 SNX5 KPNB1

1.56e-04149612121GO:0046907
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

SPAG1 RAP1GAP TTC39C CNTRL ATP8B1 DNAH7 ACTR2 NME8 IQCB1 CFAP57 ARHGEF26 DNAH5 DNAH8

1.57e-0467012113GO:0120031
GeneOntologyBiologicalProcesscell projection assembly

SPAG1 RAP1GAP TTC39C CNTRL ATP8B1 DNAH7 ACTR2 NME8 IQCB1 CFAP57 ARHGEF26 DNAH5 DNAH8

1.95e-0468512113GO:0030031
GeneOntologyBiologicalProcesspositive regulation of low-density lipoprotein particle clearance

ANXA2 ANXA2P2

2.03e-0441212GO:1905581
GeneOntologyBiologicalProcessnegative regulation of receptor catabolic process

ANXA2 ANXA2P2

2.03e-0441212GO:2000645
GeneOntologyBiologicalProcessRNA import into nucleus

SNUPN KPNB1

2.03e-0441212GO:0006404
GeneOntologyBiologicalProcesspositive regulation of intracellular cholesterol transport

ANXA2 ANXA2P2

2.03e-0441212GO:0032385
GeneOntologyBiologicalProcesspositive regulation of intracellular sterol transport

ANXA2 ANXA2P2

2.03e-0441212GO:0032382
GeneOntologyBiologicalProcessregulation of plasma membrane organization

ANXA2 ANXA2P2 ATP8B1

2.09e-04201213GO:1903729
GeneOntologyBiologicalProcessmicrotubule bundle formation

SPAG1 CNTRL DNAH7 CFAP57 DNAH5 DNAH8

2.15e-041451216GO:0001578
GeneOntologyBiologicalProcesscilium assembly

SPAG1 TTC39C CNTRL DNAH7 ACTR2 NME8 IQCB1 CFAP57 DNAH5 DNAH8

2.91e-0444412110GO:0060271
GeneOntologyBiologicalProcessRNA localization

EXOSC10 POLDIP3 SNUPN LRPPRC NXF5 NXF2 KPNB1

2.97e-042171217GO:0006403
GeneOntologyBiologicalProcesspositive regulation of plasma membrane repair

ANXA2 ANXA2P2

3.37e-0451212GO:1905686
GeneOntologyBiologicalProcessregulation of low-density lipoprotein particle receptor binding

ANXA2 ANXA2P2

3.37e-0451212GO:1905595
GeneOntologyBiologicalProcesspositive regulation of intracellular lipid transport

ANXA2 ANXA2P2

3.37e-0451212GO:0032379
GeneOntologyBiologicalProcesspoly(A)+ mRNA export from nucleus

POLDIP3 NXF5 NXF2

4.12e-04251213GO:0016973
GeneOntologyCellularComponentaxonemal dynein complex

DNAH7 NME8 DNAH5 DNAH8

1.27e-05251224GO:0005858
GeneOntologyCellularComponentouter dynein arm

NME8 DNAH5 DNAH8

4.11e-05121223GO:0036157
GeneOntologyCellularComponent9+2 motile cilium

DNAH7 NME8 AKAP9 TTC29 NXF2 CFAP57 DNAH5 DNAH8

7.92e-052381228GO:0097729
GeneOntologyCellularComponentAnxA2-p11 complex

ANXA2 ANXA2P2

1.01e-0431222GO:1990665
GeneOntologyCellularComponentPCSK9-AnxA2 complex

ANXA2 ANXA2P2

1.01e-0431222GO:1990667
GeneOntologyCellularComponentdynein complex

DNAH7 NME8 DNAH5 DNAH8

2.79e-04541224GO:0030286
GeneOntologyCellularComponentnuclear RNA export factor complex

NXF5 NXF2

6.96e-0471222GO:0042272
GeneOntologyCellularComponentmyelin sheath adaxonal region

ANXA2 ANXA2P2

6.96e-0471222GO:0035749
GeneOntologyCellularComponentbasement membrane

LAMB4 ANXA2 ANXA2P2 LAMA1 MMRN2

7.50e-041221225GO:0005604
GeneOntologyCellularComponentmotile cilium

DNAH7 NME8 AKAP9 TTC29 NXF2 CFAP57 DNAH5 DNAH8

1.15e-033551228GO:0031514
GeneOntologyCellularComponentaxoneme

EFCAB6 CNTRL DNAH7 NME8 DNAH5 DNAH8

1.37e-032071226GO:0005930
GeneOntologyCellularComponentciliary plasm

EFCAB6 CNTRL DNAH7 NME8 DNAH5 DNAH8

1.40e-032081226GO:0097014
GeneOntologyCellularComponentNLS-dependent protein nuclear import complex

SNUPN KPNB1

1.47e-03101222GO:0042564
GeneOntologyCellularComponentpinosome

ANXA2 ANXA2P2

1.80e-03111222GO:0044352
GeneOntologyCellularComponentcohesin complex

RAD21L1 SGO2

1.80e-03111222GO:0008278
GeneOntologyCellularComponentmacropinosome

ANXA2 ANXA2P2

1.80e-03111222GO:0044354
GeneOntologyCellularComponentmidbody

TTC28 ANXA2 ANXA2P2 NEXMIF CNTRL CEP55

1.95e-032221226GO:0030496
GeneOntologyCellularComponentvoltage-gated potassium channel complex

AKAP9 KCNJ16 KCNS3 KCNH5

2.00e-03911224GO:0008076
GeneOntologyCellularComponentnucleocytoplasmic transport complex

SNUPN KPNB1

2.15e-03121222GO:0031074
DomainTPR-like_helical_dom

SPAG1 TTC24 TTC28 TTC39C TTC6 TOMM70 LRPPRC SUGT1 NAPB TTC29 TOMM34 SEL1L2 NAA16

4.19e-0923312213IPR011990
Domain-

SPAG1 TTC24 TTC28 TTC39C TOMM70 LRPPRC SUGT1 NAPB TTC29 TOMM34 SEL1L2 NAA16

1.11e-08207122121.25.40.10
DomainTPR_REGION

SPAG1 TTC24 TTC28 TTC39C TTC6 TOMM70 SUGT1 TTC29 TOMM34 NAA16

1.30e-0716512210PS50293
DomainTPR

SPAG1 TTC24 TTC28 TTC39C TTC6 TOMM70 SUGT1 TTC29 TOMM34 NAA16

1.30e-0716512210PS50005
DomainTPR_1

SPAG1 TTC24 TTC28 TTC6 TOMM70 SUGT1 TOMM34 NAA16

1.30e-07901228IPR001440
DomainTPR_1

SPAG1 TTC24 TTC28 TTC6 TOMM70 SUGT1 TOMM34 NAA16

1.30e-07901228PF00515
DomainTPR

SPAG1 TTC24 TTC28 TTC6 TOMM70 SUGT1 TTC29 TOMM34 NAA16

1.71e-071291229SM00028
DomainTPR-contain_dom

SPAG1 TTC24 TTC28 TTC6 TOMM70 SUGT1 TTC29 TOMM34 NAA16

6.16e-071501229IPR013026
DomainTPR_repeat

SPAG1 TTC24 TTC28 TOMM70 SUGT1 TTC29 TOMM34 NAA16

2.61e-061331228IPR019734
DomainPept_cys_AS

CAPN2 CAPN8 CAPN5 DNAH8

3.14e-05281224IPR000169
Domaincalpain_III

CAPN2 CAPN8 CAPN5

5.73e-05121223SM00720
DomainC2_III

CAPN2 CAPN8 CAPN5

5.73e-05121223IPR033883
DomainCalpain_III

CAPN2 CAPN8 CAPN5

5.73e-05121223IPR022683
DomainCalpain_III

CAPN2 CAPN8 CAPN5

7.41e-05131223PF01067
DomainCalpain_domain_III

CAPN2 CAPN8 CAPN5

7.41e-05131223IPR022682
DomainDynein_heavy_chain_D4_dom

DNAH7 DNAH5 DNAH8

9.39e-05141223IPR024317
DomainDynein_HC_stalk

DNAH7 DNAH5 DNAH8

9.39e-05141223IPR024743
DomainDynein_heavy_dom-2

DNAH7 DNAH5 DNAH8

9.39e-05141223IPR013602
DomainDHC_N2

DNAH7 DNAH5 DNAH8

9.39e-05141223PF08393
DomainCalpain_cysteine_protease

CAPN2 CAPN8 CAPN5

9.39e-05141223IPR022684
DomainMT

DNAH7 DNAH5 DNAH8

9.39e-05141223PF12777
DomainAAA_8

DNAH7 DNAH5 DNAH8

9.39e-05141223PF12780
DomainDHC_fam

DNAH7 DNAH5 DNAH8

1.17e-04151223IPR026983
DomainPeptidase_C2

CAPN2 CAPN8 CAPN5

1.17e-04151223PF00648
DomainDynein_heavy

DNAH7 DNAH5 DNAH8

1.17e-04151223PF03028
DomainCysPc

CAPN2 CAPN8 CAPN5

1.17e-04151223SM00230
DomainPeptidase_C2_calpain_cat

CAPN2 CAPN8 CAPN5

1.17e-04151223IPR001300
DomainDynein_heavy_dom

DNAH7 DNAH5 DNAH8

1.17e-04151223IPR004273
DomainCALPAIN_CAT

CAPN2 CAPN8 CAPN5

1.17e-04151223PS50203
DomainNXF_fam

NXF5 NXF2

1.26e-0431222IPR030217
DomainTap_RNA_bd

NXF5 NXF2

2.52e-0441222PD043466
DomainTap_RNA-bd

NXF5 NXF2

2.52e-0441222IPR015245
DomainTap-RNA_bind

NXF5 NXF2

2.52e-0441222PF09162
DomainTPR_2

TTC28 TOMM70 SUGT1 NAA16

3.16e-04501224PF07719
DomainTPR_2

TTC28 TOMM70 SUGT1 NAA16

3.16e-04501224IPR013105
DomainPentatricopeptide_repeat

MRPS27 LRPPRC GNAS

4.38e-04231223IPR002885
DomainTHIOL_PROTEASE_CYS

CAPN2 CAPN8 CAPN5

6.33e-04261223PS00139
DomainTHIOL_PROTEASE_ASN

CAPN2 CAPN8 CAPN5

7.09e-04271223PS00640
DomainTHIOL_PROTEASE_HIS

CAPN2 CAPN8 CAPN5

7.09e-04271223PS00639
DomainAPC_su10/DOC_dom

HECTD3 HERC2

8.70e-0471222IPR004939
DomainDOC

HECTD3 HERC2

8.70e-0471222PS51284
DomainANAPC10

HECTD3 HERC2

8.70e-0471222PF03256
DomainAPC10

HECTD3 HERC2

8.70e-0471222SM01337
DomainEGF_LAM_2

LAMB4 LAMA1 CELSR1

9.71e-04301223PS50027
DomainEGF_LAM_1

LAMB4 LAMA1 CELSR1

9.71e-04301223PS01248
DomainDHC_N1

DNAH5 DNAH8

1.15e-0381222PF08385
DomainPPR

MRPS27 LRPPRC

1.15e-0381222PS51375
DomainDynein_heavy_dom-1

DNAH5 DNAH8

1.15e-0381222IPR013594
DomainNTF2_DOMAIN

NXF5 NXF2

1.48e-0391222PS50177
DomainNTF2

NXF5 NXF2

1.48e-0391222IPR002075
DomainEGF_Lam

LAMB4 LAMA1 CELSR1

1.53e-03351223SM00180
DomainLaminin_EGF

LAMB4 LAMA1 CELSR1

1.53e-03351223PF00053
DomainTPR_7

TTC24 TTC28

1.84e-03101222PF13176
DomainLaminin_EGF

LAMB4 LAMA1 CELSR1

1.94e-03381223IPR002049
Domain-

NXF5 NXF2

3.15e-031312223.10.450.50
DomainATPase_dyneun-rel_AAA

DNAH5 DNAH8

3.66e-03141222IPR011704
DomainAAA_5

DNAH5 DNAH8

3.66e-03141222PF07728
DomainNTF2-like_dom

NXF5 NXF2

4.20e-03151222IPR032710
DomainLaminin_N

LAMB4 LAMA1

4.78e-03161222IPR008211
DomainLamNT

LAMB4 LAMA1

4.78e-03161222SM00136
DomainLAMININ_NTER

LAMB4 LAMA1

4.78e-03161222PS51117
DomainLaminin_N

LAMB4 LAMA1

4.78e-03161222PF00055
DomainRabGAP-TBC

TBC1D28 TBC1D26 SGSM2

5.02e-03531223PF00566
DomainTPR_8

SPAG1 TTC28 TOMM70

5.02e-03531223PF13181
DomainHEAT_type_2

PPP4R4 KPNB1

5.40e-03171222IPR021133
DomainRab-GTPase-TBC_dom

TBC1D28 TBC1D26 SGSM2

5.57e-03551223IPR000195
DomainTBC_RABGAP

TBC1D28 TBC1D26 SGSM2

5.57e-03551223PS50086
Pubmed

Defining the membrane proteome of NK cells.

EXOSC10 ANXA2 CNTRL GEMIN5 NOL9 ACTR2 POLR3A CEP55 ITPR2 TOMM70 LRPPRC GTF3C1 TOMM34 EIF3A GNAS HERC2 KPNB1

9.19e-0711681241719946888
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

EXOSC10 ANXA2 MRPS27 GEMIN5 NOL9 ACTR2 CEP55 RHOB LRPPRC GTF3C1 IQCB1 PYGL EIF3A GNAS SNX5 KPNB1

3.48e-0611491241635446349
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

POLDIP3 KIZ ARID1A LIN9 CEP55 SUGT1 GTF3C1 KCTD10 ANAPC2 SGO2 LTV1 EIF3A GNAS HERC2 KPNB1 NAA16

3.72e-0611551241620360068
Pubmed

Primary Ciliary Dyskinesia

SPAG1 NME8 DNAH5 DNAH8

5.12e-0632124420301301
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

EXOSC10 POLDIP3 ANXA2 MRPS27 ACTR2 TTC6 POLR3A LRPPRC SUGT1 GTF3C1 IQCB1 ANAPC2 TOMM34 LTV1 EIF3A GNAS KPNB1

5.51e-0613351241729229926
Pubmed

Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.

ANXA2 ANXA2P2 LMX1B

9.51e-0612124328407732
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

EXOSC10 POLDIP3 ANXA2 MRPS27 NOL9 ACTR2 CEP55 ITPR2 LRPPRC PPP3CB GTF3C1 KCTD10 LTV1 EIF3A GNAS KPNB1

1.07e-0512571241636526897
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

HECTD3 CAPN2 ITPR2 LRPPRC KCTD10 IQCB1 HERC2

1.17e-05212124733853758
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

THSD4 SPRED2 ANXA2 CAPN2 NEB SGSM2 DNAH5

1.24e-05214124722199357
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

BIRC8 UAP1 GRK5 CAPN2 ARID1A POLR3A CAPN8 BRDT KCTD10 CAPN5 DNAH5 KCNH5

1.25e-057301241234857952
Pubmed

Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy.

ANXA2 ANXA2P2

1.26e-052124219536308
Pubmed

Annexin A2 modulates radiation-sensitive transcriptional programming and cell fate.

ANXA2 ANXA2P2

1.26e-052124223148505
Pubmed

ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.

ANXA2 ANXA2P2

1.26e-052124238290972
Pubmed

The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats.

ANXA2 ANXA2P2

1.26e-05212423013423
Pubmed

Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis.

ANXA2 ANXA2P2

1.26e-052124235064931
Pubmed

Molecular basis for the recognition of snurportin 1 by importin beta.

SNUPN KPNB1

1.26e-052124218187419
Pubmed

Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.

ANXA2 ANXA2P2

1.26e-052124228130864
Pubmed

Localization of annexin II in the paranodal regions and Schmidt-Lanterman incisures in the peripheral nervous system.

ANXA2 ANXA2P2

1.26e-052124217549680
Pubmed

Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice.

ANXA2 ANXA2P2

1.26e-052124239384746
Pubmed

Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.

ANXA2 ANXA2P2

1.26e-052124220826156
Pubmed

Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.

ANXA2 ANXA2P2

1.26e-052124227468426
Pubmed

Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.

ANXA2 ANXA2P2

1.26e-052124219841537
Pubmed

Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice.

ANXA2 ANXA2P2

1.26e-052124227389701
Pubmed

Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation.

ANXA2 ANXA2P2

1.26e-052124217360942
Pubmed

Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina.

ANXA2 ANXA2P2

1.26e-052124219587120
Pubmed

Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate.

ANXA2 ANXA2P2

1.26e-052124219022301
Pubmed

Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.

ANXA2 ANXA2P2

1.26e-052124238253182
Pubmed

Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis.

ANXA2 ANXA2P2

1.26e-052124222185818
Pubmed

A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events.

ANXA2 ANXA2P2

1.26e-052124221486955
Pubmed

Lipid raft endocytosis and exosomal transport facilitate extracellular trafficking of annexin A2.

ANXA2 ANXA2P2

1.26e-052124221737841
Pubmed

Regulation of the low-dose radiation paracrine-specific anchorage-independent growth response by annexin A2.

ANXA2 ANXA2P2

1.26e-052124219580511
Pubmed

The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations.

CAPN2 CAPN8

1.26e-052124228002826
Pubmed

Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth.

ANXA2 ANXA2P2

1.26e-052124236739096
Pubmed

Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.

ANXA2 ANXA2P2

1.26e-052124222517898
Pubmed

Association of single-nucleotide polymorphisms in RHOB and TXNDC3 with knee osteoarthritis susceptibility: two case-control studies in East Asian populations and a meta-analysis.

NME8 RHOB

1.26e-052124218471322
Pubmed

Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.

ANXA2 ANXA2P2

1.26e-052124230462534
Pubmed

Inhibition of the calcineurin-NFAT signalling cascade in the treatment of heart failure.

PPP3CB KPNB1

1.26e-052124219925438
Pubmed

Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis.

ANXA2 ANXA2P2

1.26e-052124238092984
Pubmed

Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.

ANXA2 ANXA2P2

1.26e-052124221572519
Pubmed

Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice.

ANXA2 ANXA2P2

1.26e-052124221788340
Pubmed

The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis of Cryptococcus neoformans and Impacts Survival in Fungal Infection.

ANXA2 ANXA2P2

1.26e-052124227371724
Pubmed

Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice.

ANXA2 ANXA2P2

1.26e-052124231817350
Pubmed

ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.

ANXA2 ANXA2P2

1.26e-052124237832154
Pubmed

Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice.

ANXA2 ANXA2P2

1.26e-052124230902828
Pubmed

Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis.

ANXA2 ANXA2P2

1.26e-052124224742684
Pubmed

Genetic association analysis of RHOB and TXNDC3 in osteoarthritis.

NME8 RHOB

1.26e-052124217304710
Pubmed

Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.

ANXA2 ANXA2P2

1.26e-052124232687500
Pubmed

Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.

ANXA2 ANXA2P2

1.26e-052124222453828
Pubmed

Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structure.

SNUPN KPNB1

1.26e-05212429670026
Pubmed

Agents that bind annexin A2 suppress ocular neovascularization.

ANXA2 ANXA2P2

1.26e-052124220607799
Pubmed

Strong cytolytic activity of natural killer cells is neither necessary nor sufficient for preimmune resistance to Toxoplasma gondii infection.

LYST IFNG

1.26e-05212428696010
Pubmed

A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study.

ANXA2 ANXA2P2

1.26e-052124231253864
Pubmed

Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo.

ANXA2 ANXA2P2

1.26e-052124219628708
Pubmed

Annexin A2 binds to the localization signal in the 3' untranslated region of c-myc mRNA.

ANXA2 ANXA2P2

1.26e-052124215654879
Pubmed

Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis.

ANXA2 ANXA2P2

1.26e-052124220847146
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

EXOSC10 POLDIP3 MRPS27 GEMIN5 PGAP4 MAB21L2 ACTR2 POLR3A ITPR2 TOMM70 LRPPRC SUGT1 GTF3C1 LMX1B EIF3A GNAS KPNB1

1.47e-0514401241730833792
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SPAG1 TTC24 GLS2 RAPH1 ANXA2 GRK5 CNTRL NEB ARID1A LYST ACTR2 PPP4R4 LRPPRC GTF3C1 EIF3A DNAH8 KPNB1

1.50e-0514421241735575683
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH7 DNAH5 DNAH8

1.56e-051412439373155
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TTC28 HECTD3 MRPS27 NEB ARID1A DNAH7 PPP4R4 RHOB NXF5 LTV1 CSPP1

1.89e-056381241131182584
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

EXOSC10 LAMA1 TEX15 NEB LTV1 DNAH5 PRDM16

2.20e-05234124736243803
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

EXOSC10 POLDIP3 GEMIN5 NOL9 ARID1A ACTR2 LRPPRC GTF3C1 PYGL HERC2 KPNB1

2.34e-056531241122586326
Pubmed

140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry.

RAP1GAP ANXA2 ANXA2P2 PPP3CB NAPB TOMM34

2.73e-05163124616512683
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

EXOSC10 TTC28 RAPH1 ANXA2 GEMIN5 ARID1A CEP55 SUGT1 GTF3C1 KPNB1

2.89e-055491241038280479
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

SPAG1 UAP1 POLDIP3 ANXA2 CAPN2 GEMIN5 NOL9 ARID1A TOMM70 LRPPRC SUGT1 TOMM34 PYGL EIF3A GNAS KPNB1

2.98e-0513671241632687490
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ZFP14 MIER1 PPP4R4 GPR107 DNAH5

3.20e-05101124510997877
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

RAP1GAP RAPH1 ANXA2 CAPN2 SUGT1 NAPB EIF3A GNAS SNX5 KPNB1

3.32e-055581241035063084
Pubmed

STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.

ANXA2 ANXA2P2

3.77e-053124235098646
Pubmed

The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.

ANXA2 ANXA2P2

3.77e-053124235413401
Pubmed

Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases.

ANXA2 ANXA2P2

3.77e-053124228694388
Pubmed

High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2.

ANXA2 ANXA2P2

3.77e-053124227470587
Pubmed

Annexins--unique membrane binding proteins with diverse functions.

ANXA2 ANXA2P2

3.77e-053124215169834
Pubmed

Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9.

ANXA2 ANXA2P2

3.77e-053124224808179
Pubmed

The Annexin a2 Promotes Development in Arthritis through Neovascularization by Amplification Hedgehog Pathway.

ANXA2 ANXA2P2

3.77e-053124226963384
Pubmed

Annexin A2 links poor myofiber repair with inflammation and adipogenic replacement of the injured muscle.

ANXA2 ANXA2P2

3.77e-053124228334824
Pubmed

Annexin II interactions with the annexin II receptor enhance multiple myeloma cell adhesion and growth in the bone marrow microenvironment.

ANXA2 ANXA2P2

3.77e-053124222223826
Pubmed

Annexin-2 is a regulator of stromal cell-derived factor-1/CXCL12 function in the hematopoietic stem cell endosteal niche.

ANXA2 ANXA2P2

3.77e-053124221108988
Pubmed

Unique X-linked familial FSGS with co-segregating heart block disorder is associated with a mutation in the NXF5 gene.

NXF5 ALG13

3.77e-053124223686279
Pubmed

FOXQ1 promotes the osteogenic differentiation of bone mesenchymal stem cells via Wnt/β-catenin signaling by binding with ANXA2.

ANXA2 ANXA2P2

3.77e-053124232943107
Pubmed

Prostaglandin-endoperoxide synthase-2 deletion affects the natural trafficking of Annexin A2 in monocytes and favours venous thrombosis in mice.

ANXA2 ANXA2P2

3.77e-053124228536720
Pubmed

A new subfamily of vertebrate calpains lacking a calmodulin-like domain: implications for calpain regulation and evolution.

CAPN2 CAPN5

3.77e-05312429339374
Pubmed

Annexin II is a thiazolidinedione-responsive gene involved in insulin-induced glucose transporter isoform 4 translocation in 3T3-L1 adipocytes.

ANXA2 ANXA2P2

3.77e-053124214726447
Pubmed

Mitochondrially mediated integrin αIIbβ3 protein inactivation limits thrombus growth.

ANXA2 ANXA2P2

3.77e-053124224014035
Pubmed

Annexin A2 contributes to lung injury and fibrosis by augmenting factor Xa fibrogenic activity.

ANXA2 ANXA2P2

3.77e-053124228283478
Pubmed

Annexin A2 promotes angiogenesis after ischemic stroke via annexin A2 receptor - AKT/ERK pathways.

ANXA2 ANXA2P2

3.77e-053124236367512
Pubmed

Revealing Annexin A2 and ARF-6 enrollment during Trypanosoma cruzi extracellular amastigote-host cell interaction.

ANXA2 ANXA2P2

3.77e-053124226416603
Pubmed

Annexin A2 depletion delays EGFR endocytic trafficking via cofilin activation and enhances EGFR signaling and metastasis formation.

ANXA2 ANXA2P2

3.77e-053124223792445
Pubmed

Annexin 2-CXCL12 interactions regulate metastatic cell targeting and growth in the bone marrow.

ANXA2 ANXA2P2

3.77e-053124225139998
Pubmed

Impaired osteoblast differentiation in annexin A2- and -A5-deficient cells.

ANXA2 ANXA2P2

3.77e-053124225222280
Pubmed

Macrophage surface expression of annexins I and II in the phagocytosis of apoptotic lymphocytes.

ANXA2 ANXA2P2

3.77e-053124215064349
Pubmed

Tenascin-c renders a proangiogenic phenotype in macrophage via annexin II.

ANXA2 ANXA2P2

3.77e-053124228857429
Pubmed

Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B.

ANXA2 ANXA2P2

3.77e-053124231160583
Pubmed

Inhibition of ANXA2 regulated by SRF attenuates the development of severe acute pancreatitis by inhibiting the NF-κB signaling pathway.

ANXA2 ANXA2P2

3.77e-053124235900381
Pubmed

Annexin A2 promotes phagophore assembly by enhancing Atg16L⁺ vesicle biogenesis and homotypic fusion.

ANXA2 ANXA2P2

3.77e-053124225597631
Pubmed

Annexin A2 regulates TRPA1-dependent nociception.

ANXA2 ANXA2P2

3.77e-053124225355205
Pubmed

Complete structure of the murine p36 (annexin II) gene. Identification of mRNAs for both the murine and the human gene with alternatively spliced 5' noncoding exons.

ANXA2 ANXA2P2

3.77e-05312428634333
Pubmed

RNASEH1-AS1 induced by H3K27ac stabilizes ANXA2 mRNA to promote the progression of colorectal cancer through recruiting BUD13.

ANXA2 ANXA2P2

3.77e-053124238053379
Pubmed

Chromosomal localization of the human genes for lipocortin I and lipocortin II.

ANXA2 ANXA2P2

3.77e-05312422969496
Pubmed

Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation.

ANXA2 ANXA2P2

3.77e-053124237690046
Pubmed

Trigger-dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis.

LYST IFNG

3.77e-053124232419134
Pubmed

The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation.

ANXA2 ANXA2P2

3.77e-053124227045038
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

SPAG1 TTC24 TTC28 TTC39C TTC6 TOMM70 TTC29 TOMM34 NAA16

3.07e-09115849769
GeneFamilyC2 domain containing|Calpains

CAPN2 CAPN8 CAPN5

4.23e-0515843975
GeneFamilyDyneins, axonemal

DNAH7 DNAH5 DNAH8

6.28e-0517843536
GeneFamilyLaminin subunits

LAMB4 LAMA1

1.37e-0312842626
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_200

LRRC34 TEX15 ADAM22 BRDT IQCB1 DNAH8 ALG13

1.90e-051431227gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_200
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_500

LRRC34 TEX15 ADAM22 LRPPRC BRDT IQCB1 SGO2 LTV1 DNAH8 RNF182 ALG13

2.29e-0540612211gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_500
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#2_top-relative-expression-ranked_500

TEX15 ADAM22 BRDT IQCB1 DNAH8

4.50e-05681225gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k2_500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

LRRC34 KIZ TEX15 LYST ADAM22 PPP4R4 LRPPRC BRDT IQCB1 SGO2 LTV1 DNAH8 RNF182 NAA16 ALG13

7.34e-0582012215gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGEF38 ATP8B1 DNAH7 TTC6 PPP4R4 CELSR1 CTNNA3 DNAH5 PRDM16

3.45e-09191124960ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NEXMIF ARHGEF38 TTC6 PPP4R4 SLC25A36 CELSR1 UGT2B15 PRDM16

2.12e-081651248f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

THSD4 NEXMIF ARHGEF38 TTC6 CAPN8 CELSR1 DNAH5 PRDM16

5.15e-081851248cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA1 ARHGEF38 TTC6 CEP55 CELSR1 CTNNA3 SGO2 PRDM16

6.86e-08192124825378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 ANXA2 ARHGEF38 ATP8B1 TTC6 CAPN8 CELSR1 TMEM63A

9.39e-082001248d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TMPRSS13 ARHGEF38 DNAH7 CELSR1 TTC29 DNAH5 PRDM16

4.12e-0716512470c714e852f912b5749de4cb0895406673979b2e6
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TMPRSS13 ARHGEF38 DNAH7 CELSR1 TTC29 DNAH5 PRDM16

4.12e-07165124782530f96aaefe28a13bad0474bbad043f127a86c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGEF38 TTC6 PPP4R4 CAPN8 CELSR1 DNAH5 PRDM16

9.23e-0718612472ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

LRRC34 SPAG1 PSENEN MUC12 DNAH7 CFAP57 DNAH5

9.91e-0718812476833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

THSD4 ARHGEF38 TTC6 CAPN8 CELSR1 DNAH5 PRDM16

9.91e-071881247c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

THSD4 ARHGEF38 TTC6 CAPN8 CELSR1 DNAH5 PRDM16

1.14e-061921247efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGEF38 ATP8B1 DNAH7 TTC6 CELSR1 LMX1B PRDM16

1.14e-061921247b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TMPRSS13 ARHGEF38 TTC6 CELSR1 UGT2B15 DNAH5 PRDM16

1.18e-061931247b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

NEXMIF ARHGEF38 TTC6 CAPN8 CELSR1 DNAH5 PRDM16

1.18e-0619312472bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellASK440-Epithelial-Ciliated|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

SPAG1 PSENEN DNAH7 TTC29 CFAP57 DNAH5 CSPP1

1.18e-061931247a0baa8be6f590b2031fede22be588715ae458e93
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TMPRSS13 ARHGEF38 DNAH7 PPP4R4 CELSR1 DNAH5 PRDM16

1.22e-0619412476b286992d4bb56013c0ea5a7601d3476d806175a
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGEF38 DNAH7 TTC6 CELSR1 CTNNA3 DNAH5 PRDM16

1.22e-061941247f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 EFCAB6 DNAH7 TTC29 CFAP57 DNAH5 CSPP1

1.22e-0619412474a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 RAPH1 NEXMIF ATP8B1 TTC6 CAPN8 PRDM16

1.27e-0619512473d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

THSD4 NEXMIF CAPN2 ARHGEF38 KCNJ16 DNAH5 PRDM16

1.31e-06196124704f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LRRC34 CNTRL DNAH7 TTC29 CFAP57 DNAH5 CSPP1

1.40e-061981247ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellFetal_29-31_weeks-Epithelial-club_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NEXMIF ARHGEF38 TTC6 CAPN8 CELSR1 DNAH5 PRDM16

1.40e-0619812475fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NEXMIF ARHGEF38 TTC6 CAPN8 CELSR1 DNAH5 PRDM16

1.40e-0619812476ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGEF38 TTC6 PPP4R4 CAPN8 CELSR1 DNAH5

3.71e-0614812469fe3c0a5904b8e9a0f28130f8d84d4f2a819b06c
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGEF38 TTC6 TBC1D26 CAPN8 CELSR1 DNAH5

6.24e-0616212465c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCellLPS-IL1RA-Epithelial_airway-Club_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMPRSS13 ARHGEF38 TTC6 PPP4R4 CELSR1 PRDM16

6.94e-0616512461a114eacaab598f755a173a3fed842ba91f689dd
ToppCellLPS-IL1RA-Epithelial_airway-Club_cells-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMPRSS13 ARHGEF38 TTC6 PPP4R4 CELSR1 PRDM16

6.94e-0616512469cfd3c1d2c6d714fde83b90465f1f9741b0e50ce
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

RAP1GAP ARHGEF38 DNAH7 CAPN8 CAPN5 TMEM63A

8.23e-061701246d682178d11d67eb5a02d0c6b3967645e37bcc62a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCHS2 NPY1R ITPR2 CAPN8 TTC29 KCNH5

8.23e-06170124684d49a1f2989d98bd0acf9ec2d59f1042fc0f55b
ToppCellThalamus-Neuronal-Excitatory|Thalamus / BrainAtlas - Mouse McCarroll V32

TRAIP TEX15 PPP4R4 PPP3CB NAPB KCNH5

1.00e-051761246d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC34 EFCAB6 TTC29 ACSBG2 CFAP57 DNAH5

1.07e-05178124658857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC34 EFCAB6 TTC29 ACSBG2 CFAP57 DNAH5

1.07e-0517812468b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC34 EFCAB6 TTC29 ACSBG2 CFAP57 DNAH5

1.07e-051781246b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGEF38 TTC6 SLC25A36 CELSR1 CTNNA3 PRDM16

1.10e-051791246815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NEXMIF ARHGEF38 TTC6 CAPN8 CELSR1 DNAH5

1.14e-051801246b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SPAG1 EFCAB6 DNAH7 TTC29 CFAP57 DNAH5

1.18e-051811246dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB4 NEXMIF ARHGEF38 CAPN8 KCNJ16 GNAS

1.29e-051841246d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 LAMB4 ARHGEF38 CAPN8 KCNJ16 GNAS

1.29e-0518412468fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LRRC34 EFCAB6 DNAH7 TTC29 CFAP57 DNAH5

1.33e-0518512465e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

ARHGEF38 TTC6 CAPN8 CELSR1 DNAH5 PRDM16

1.41e-05187124681cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ARHGEF38 TTC6 CEP55 CELSR1 SGO2 PRDM16

1.50e-051891246c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 NEXMIF KIZ ATP8B1 ADAM22 PRDM16

1.55e-051901246b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

NEXMIF ARHGEF38 TTC6 CAPN8 CELSR1 DNAH5

1.55e-05190124651ca9ef4df3220487152fcf684147730637c7cc1
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGEF38 TTC6 CAPN8 CELSR1 DNAH5 PRDM16

1.59e-05191124623776c7302cead3881b39127398f3b3e0d27885e
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD4 RAP1GAP NEXMIF ARHGEF38 ADAM22 CELSR1

1.64e-05192124613e4b17d7a592604140777aca235f795df6b3f91
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 RAPH1 ANXA2 NEXMIF KIZ ATP8B1

1.64e-0519212462510f22197502f60fd266b7f42eff040f25b8ae7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 RAPH1 ANXA2 NEXMIF KIZ ATP8B1

1.64e-051921246e8e316f396834bcd34843e56e1d86f310fd6aada
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD4 RAP1GAP NEXMIF ARHGEF38 ADAM22 CELSR1

1.64e-0519212466244541688f85917018a057aa0b3e5972934dfbc
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP LAMA1 NEB ITPR2 AKAP9 KCNJ16

1.64e-051921246ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DCHS2 RGSL1 EFCAB6 NXF5 ACSBG2 DNAH8

1.69e-051931246315840bc48899f3a36d57b19197509de19716e3d
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TMPRSS13 ARHGEF38 TTC6 CELSR1 DNAH5 PRDM16

1.69e-051931246b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCellASK452-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

LRRC34 DNAH7 TTC29 CFAP57 DNAH5 CSPP1

1.69e-051931246c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRRC34 SPAG1 DNAH7 TTC29 CFAP57 DNAH5

1.69e-051931246e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH7 SLC25A36 CELSR1 CFAP57 DNAH5 CSPP1

1.69e-051931246ea345d34440b25f65358a53dc72831998d1c3620
ToppCellCOVID-19-kidney-CD-PC|kidney / Disease (COVID-19 only), tissue and cell type

THSD4 NEXMIF KIZ ARHGEF38 ATP8B1 PRDM16

1.69e-051931246738689d009e4b118d7ce3171a207294b95cbe78b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 RAPH1 NEXMIF ATP8B1 CAPN8 PRDM16

1.74e-0519412464579b4a44f7c731553a284843c296866027d7c0e
ToppCellASK440-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

SPAG1 PSENEN DNAH7 TTC29 CFAP57 CSPP1

1.74e-051941246c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LRRC34 EFCAB6 DNAH7 TTC29 CFAP57 DNAH5

1.74e-0519412461ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGEF38 TTC6 CELSR1 LMX1B KCNJ16 PRDM16

1.74e-051941246b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRRC34 SPAG1 DNAH7 TTC29 DNAH5 CSPP1

1.79e-051951246d211a836cf711fdb91b10d512f09d462be937cc5
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LRRC34 DNAH7 TTC29 CFAP57 DNAH5 CSPP1

1.79e-0519512463486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LRRC34 DNAH7 TTC29 CFAP57 DNAH5 CSPP1

1.79e-051951246e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Ciliated|Control_saline / Treatment groups by lineage, cell group, cell type

SPAG1 ARHGEF38 DNAH7 TTC6 TTC29 DNAH5

1.79e-05195124660067b5359174f0d1a8b5748bfc0690762e9e740
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LRRC34 DNAH7 TTC29 CFAP57 DNAH5 CSPP1

1.85e-05196124627b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP LAMA1 ARHGEF38 DNAH7 KCNJ16 PRDM16

1.85e-051961246eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPAG1 DNAH7 TTC29 CFAP57 DNAH5 CSPP1

1.90e-05197124671fea4aa6ce96c7693fa94792d08770622873850
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EFCAB6 DNAH7 AKAP9 CFAP57 DNAH5 CSPP1

1.90e-05197124674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellControl_saline-Epithelial_airway|Control_saline / Treatment groups by lineage, cell group, cell type

ARHGEF38 DNAH7 TTC6 CELSR1 TTC29 DNAH5

1.95e-051981246e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCellControl_saline-Epithelial_airway-airway_epithelial|Control_saline / Treatment groups by lineage, cell group, cell type

ARHGEF38 DNAH7 TTC6 CELSR1 TTC29 DNAH5

1.95e-051981246e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 ARHGEF38 TTC6 CAPN8 CELSR1 PRDM16

2.01e-0519912465f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

SPAG1 ANXA2 CNTRL AKAP9 GNAS CSPP1

2.01e-05199124661b1ed2db71b96157b92b7535d1955a4033098da
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 ARHGEF38 TTC6 CAPN8 CELSR1 PRDM16

2.01e-0519912465cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 ARHGEF38 TTC6 CAPN8 CELSR1 TMEM63A

2.07e-052001246c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCell(09)_Interm._secr.>cil.|World / shred by cell type by condition

PSENEN CNTRL DNAH7 CFAP57 DNAH5 CSPP1

2.07e-0520012463305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRRC34 SPAG1 DNAH7 TTC29 CFAP57 DNAH5

2.07e-052001246f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

LRRC34 SPAG1 DNAH7 TTC29 CFAP57 DNAH5

2.07e-052001246d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 ARHGEF38 ATP8B1 TTC6 CAPN8 TMEM63A

2.07e-0520012460eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRRC34 SPAG1 DNAH7 TTC29 CFAP57 DNAH5

2.07e-052001246cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Intermediate|GW19 / Sample Type, Dataset, Time_group, and Cell type.

NEXMIF TRAIP ZNF283 DNAH5 PRDM16

2.17e-051201245eb5b88c47dd4a6f9b55ace24f19d4e81d4ed31e1
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPAG1 GEMIN5 SETD4 NAPB NXF2

3.07e-051291245cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCellSubstantia_nigra-Macroglia-CSF_related|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

LRRC34 EFCAB6 NME8 TTC29 ACSBG2

3.96e-05136124547663c5d81c766a333207a44fc5b58b07309ee76
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

LRRC34 EFCAB6 NME8 TTC29 ACSBG2

3.96e-0513612456d2e5b871f4cf8d64e6fe0be666fb3490797c635
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

LRRC34 EFCAB6 NME8 TTC29 ACSBG2

3.96e-051361245fd4269d194c7c11c6ab4383393a01efab05cbace
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

LRRC34 EFCAB6 NME8 TTC29 ACSBG2

3.96e-0513612453f6cec8d52c84191f7f6e2dd4dc47524dfd5b21b
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

LRRC34 EFCAB6 NME8 TTC29 ACSBG2

3.96e-05136124567d736096d6b6ddb4722809557f5e987063b8d23
ToppCellfacs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM22 CEP55 IFNG SGO2 DNAH8

7.82e-0515712450fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

TTC6 CTNNA3 SEL1L2 DNAH8 KCNH5

8.30e-0515912455335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ATP8B1 TTC6 CAPN8 CELSR1 SGSM2

8.81e-0516112452d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellLPS-IL1RA-Epithelial_airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF38 TTC6 PPP4R4 CELSR1 DNAH5

8.81e-051611245472c354f5ee148b37a5dfb795e83348ecb1643f1
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

TRAIP ADAM22 CEP55 MMRN2 SGO2

9.07e-051621245a957c7e347189b72fbd47db3075bb5e879a21c67
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GEMIN5 ADAM22 NAPB BRDT KPNB1

9.33e-051631245132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TRAIP ADAM22 CEP55 MMRN2 SGO2

9.89e-051651245a5c3af634d2698f9a01cf074791756b7669f9fff
ToppCellLPS-antiTNF-Epithelial_airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF38 TTC6 PPP4R4 CELSR1 PRDM16

1.02e-041661245eb942ed68677e55c46cb039046f45686d4062d7c
ToppCellLPS-antiTNF-Epithelial_airway-Club_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF38 TTC6 PPP4R4 CELSR1 PRDM16

1.02e-0416612451df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d
ToppCellLPS-antiTNF-Epithelial_airway-Club_cells-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF38 TTC6 PPP4R4 CELSR1 PRDM16

1.02e-0416612459628522e7af8f8edca733588a364ab2454ac5ca5
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SPRED2 TTC28 NEB ANAPC2 DPY19L4

1.05e-041671245b5d15773be32cd277125fd3b4056a8fefaefa5ec
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Club_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF38 TTC6 PPP4R4 CELSR1 DNAH5

1.11e-0416912458c96e1baa38ec5e777e627ab9dbce025e771f2c0
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Club_cells-Airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF38 TTC6 PPP4R4 CELSR1 DNAH5

1.11e-04169124586041be5d3aeab5b9269f7912791b944f325a1b4
ToppCellT_cells-GNLY+GZMB+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

NME8 CAPN8 IFNG RHOB NAPB

1.17e-04171124504c811817cfec45af5f2891793106cc7ddb0300e
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEX15 SLFN14 LYST RHOB PYGL

1.20e-041721245d354424c1f861b6607dfd63b9724f4c237b30275
ComputationalNeighborhood of CRKL

SPRED2 POLDIP3 ZFP14 GPR107 HERC2

5.35e-0564695GCM_CRKL
Diseasehereditary spastic paraplegia 76 (implicated_via_orthology)

CAPN2 CAPN8

1.57e-0451182DOID:0110821 (implicated_via_orthology)
Diseaseaortic stenosis

SPRED2 ACTR2 ARHGEF26

2.58e-04311183EFO_0000266
Diseasehypothyroidism (biomarker_via_orthology)

ANXA2 ANXA2P2 IFNG TOMM70

3.04e-04801184DOID:1459 (biomarker_via_orthology)
DiseaseE3 ubiquitin-protein ligase ZNRF3 measurement

SLFN14 PPP4R4

3.29e-0471182EFO_0021943
DiseasePrimary ciliary dyskinesia

SPAG1 NME8 DNAH5

4.04e-04361183cv:C0008780
Diseasefocal segmental glomerulosclerosis (is_marker_for)

RAP1GAP PPP3CB

4.37e-0481182DOID:1312 (is_marker_for)
DiseaseFocal Segmental Glomerulosclerosis, Not Otherwise Specified

LMX1B NXF5

5.60e-0491182C4049702
Disease3-phenylpropionate hydrocinnamate measurement

LAMA1 TTC6

6.99e-04101182EFO_0021010
Diseasechildhood trauma measurement, smoking behaviour measurement

RAD21L1 LRPPRC CTNNA3

7.83e-04451183EFO_0005671, EFO_0007979
Diseaserenal cell carcinoma (biomarker_via_orthology)

ANXA2 ANXA2P2

1.40e-03141182DOID:4450 (biomarker_via_orthology)
Diseasevelopharyngeal dysfunction

DCHS2 TTC28 LAMA1 ITPR2

1.48e-031221184EFO_0009336
DiseaseMeckel-Gruber syndrome

CEP55 CSPP1

1.61e-03151182C0265215
Diseaseadverse effect, response to xenobiotic stimulus

GLS2 LAMA1 CTNNA3

1.72e-03591183EFO_0009658, GO_0009410
Diseaseobesity (implicated_via_orthology)

DCHS2 NPY1R CAPN2 ITPR2 CAPN8

1.76e-032151185DOID:9970 (implicated_via_orthology)
Diseaseinterstitial lung disease

LRRC34 SPAG1 CTNNA3

2.48e-03671183EFO_0004244
Diseaseinosine measurement

CTNNA3 KCNH5

2.59e-03191182EFO_0010503
Diseaseintellectual disability (implicated_via_orthology)

CAPN2 CAPN8 NAA16

3.41e-03751183DOID:1059 (implicated_via_orthology)
DiseaseBronchiectasis

NME8 DNAH5

3.48e-03221182C0006267
DiseaseKidney Failure

IFNG LMX1B

3.48e-03221182C0035078
Diseaseurate measurement, bone density

THSD4 TTC28 GPR107 ITPR2 KCNS3 SEL1L2 DNAH8 KCNH5

3.49e-036191188EFO_0003923, EFO_0004531
Diseasecotinine measurement

UGT2B15 SEL1L2

3.80e-03231182EFO_0007813

Protein segments in the cluster

PeptideGeneStartEntry
VTQLCEDQALYIKKY

TMCO5A

156

Q8N6Q1
LNFNQYYEACRKAAK

ACSBG2

81

Q5FVE4
EAKYYLVQGLVEECQ

KCTD10

111

Q9H3F6
YQELQEEYACLLKVK

AKAP9

861

Q99996
CQKQYELEQELAFYK

CNTRL

346

Q7Z7A1
CQAVLYEILYKDVFV

ALG13

361

Q9NP73
RAALEAYCKKYEQLK

ANAPC2

616

Q9UJX6
LKAAAENQEYLIDKY

ANKRD23

116

Q86SG2
KRLENKYYAKASECI

BRDT

81

Q58F21
YSAEELYQAKRKCNA

ARHGEF38

581

Q9NXL2
LYQAKRKCNATQEYD

ARHGEF38

586

Q9NXL2
KVTASDKYCYEKLNI

ADAM22

561

Q9P0K1
EGYLQEEKQKCYNDL

CEP55

226

Q53EZ4
NAVLYQNYKEKALDI

ARHGEF26

376

Q96DR7
QDTKGDYQKALLYLC

ANXA2

321

P07355
ALVEKAYAKLAGCYQ

CAPN5

161

O15484
LEKAYAKLNGCYEAL

CAPN8

181

A6NHC0
QCKENYYKLLAQDTC

CELSR1

1986

Q9NYQ6
QDTKGDYQKALLYLC

ANXA2P2

321

A6NMY6
IKEKLCYVGYNIEQE

ACTR2

216

P61160
CIKESKYANNAIKTY

ATP8B1

86

O43520
IYNRKAKYLLADCSE

RAD21L1

66

Q9H4I0
QKKSQYIKYLCCDDV

RAPH1

476

Q70E73
YLDEDVNYCILKKQS

GPR107

101

Q5VW38
DYRKNQEYIAKNFCV

ITPR2

566

Q14571
SLKKQYIQCLYAFEC

ARID1A

1091

O14497
KPSCKNNYENYIDIV

NOL9

376

Q5SY16
CDVGAYYAAKLLQKQ

LRRC34

136

Q8IZ02
DLNKVLHKVQQYCYE

LIN9

401

Q5TKA1
EVLNDYYKEKAENCV

LTV1

296

Q96GA3
YYKEKAENCVKLNTL

LTV1

301

Q96GA3
YSCKQVLEEKLKYAI

HERC2

4771

O95714
IKYVKDCNCQKLYLD

MMRN2

486

Q9H8L6
DNISYADCLKQLYIK

SMPDL3A

436

Q92484
ECCNNQKLLLEYEKY

CFAP57

781

Q96MR6
GKQCCLYINYSEEIK

ERVMER34-1

441

Q9H9K5
DNYESNCFEVLLYKK

KCNH5

86

Q8NCM2
YKIYDDENQKICIFV

NXF5

71

Q9H1B4
YDEAIKCYRNALKLD

NAA16

96

Q6N069
KEEEEKYNLQLQHYC

CSPP1

851

Q1MSJ5
ICTNKYKEKIINENY

FAM214A

651

Q32MH5
KDNVRYLYTLEKVCQ

DNAH8

231

Q96JB1
LAQKFYVLYKLCEEQ

DNAH8

1996

Q96JB1
YVLYKLCEEQLTKQV

DNAH8

2001

Q96JB1
ALEVAIDCYEKYKVL

LRPPRC

841

P42704
DCNKAEKFDFVLQYL

GLS2

281

Q9UI32
KYYQKQKDIDVDQCS

KCNS3

411

Q9BQ31
KVYNQIKEFIYACLK

EXOC6B

496

Q9Y2D4
KEKQDYVYCLESSLQ

PGAP4

186

Q9BRR3
QLCYNVAKLIYLCKE

TMEM63A

261

O94886
DLEKKLYEYNQSDTC

KIZ

36

Q2M2Z5
LYEYNQSDTCRVKLK

KIZ

41

Q2M2Z5
VSNEEKLNLCRKYYL

PSENEN

6

Q9NZ42
AKQILDYENGNKYCL

DCHS2

2836

Q6V1P9
DYENGNKYCLTVQAK

DCHS2

2841

Q6V1P9
NVTLDAYKDKYVCFD

NPY1R

186

P25929
CKQDLLAYLEQIKFY

CTNNA3

761

Q9UI47
LLKLYCNVDSNKQYQ

EXOSC10

406

Q01780
CKYLLEEKGHEYINN

BIRC8

66

Q96P09
LAKEGLYQYKNICQQ

EIF3A

66

Q14152
QVLKDFCYKLTDNQY

EFCAB6

1096

Q5THR3
NHSYEKIIDEICKYQ

DNAH7

516

Q8WXX0
YKANYLIVEDAICNE

DPY19L4

636

Q7Z388
NDYSKYINKEILRCE

LYST

1706

Q99698
AKLVYQLNKYYTERC

MAB21L2

6

Q9Y586
IGLKNYAEYQVCLAA

KPNB1

656

Q14974
LKKIKQDIYCYDLIQ

IQCB1

46

Q15051
KNEIVEQEKKYARCY

LAMB4

1746

A4D0S4
CYCQDPYVKEAENLK

IFNG

21

P01579
QDEKYYQICESVLKE

HDAC8

236

Q9BY41
CSKKERVYVYCINNK

DEFB123

36

Q8N688
VVNLAYAYETKDALC

GRK5

246

P34947
LEKAYAKINGCYEAL

CAPN2

181

P17655
LDVYNNKAAVLKYEN

PPP3CB

321

P16298
AKDNVKYLYTLEKCC

DNAH5

341

Q8TE73
KDNEQALYELVKCNF

MIER1

251

Q8N108
DAITAYKKYNNRCLD

POLDIP3

326

Q9BY77
SYKIYDDENQKICIF

NXF2

181

Q9GZY0
CLKYDAQDKALYTLV

MRPS27

116

Q92552
IQKISDDYKIYCEKA

RGSL1

591

A5PLK6
IQAYDYLECSAKTKE

RHOB

151

P62745
ILNVYQKDVLDGYVC

SLFN14

296

P0C7P3
LCKDQVYYIKKYQEV

TMCO5B

171

A8MYB1
QEKKYISVRKNCAYN

PPP4R4

366

Q6NUP7
VLQNCEVALSYYKKV

SEL1L2

231

Q5TEA6
AQKSYYEALLLDKCN

NEXMIF

231

Q5QGS0
AKYFEELELYRKQCN

HMGB4

151

Q8WW32
EYQLIDCAQYFLDKI

GNAS

811

Q5JWF2
NKAKDCYYDESVAKQ

LAMA1

331

P25391
CYYDESVAKQKKSLN

LAMA1

336

P25391
CQISEQIYYKVIKDI

PRDM16

186

Q9HAZ2
LDKVVQYLAENCSKY

SGSM2

141

O43147
LTKLINAEYACYKAE

RAP1GAP

366

P47736
NAEYACYKAEKFAKL

RAP1GAP

371

P47736
LLNAGYKKCDEYIEA

POLR3A

716

O14802
NEKTSLDIAQKICYY

SETD4

371

Q9NVD3
CDYDTQNILELKKYV

SGO2

876

Q562F6
AIYFAAYSNCKEKLN

SLC25A36

96

Q96CQ1
DELECKICYNRYNLK

RNF182

16

Q8N6D2
KQQELCDILVAYSAY

TBC1D26

166

Q86UD7
AKDYTILDCIYNEVN

SNUPN

166

O95149
NQKLYLLCSRKYEAD

RNASE13

131

Q5GAN3
CYLVLKQYTEAVKDC

TOMM34

236

Q15785
QVNLIDFKKCNDYLV

TMPRSS13

471

Q9BYE2
QALKYYKEALAQCQK

TTC24

371

A2A3L6
YCLKQYELAEEDLNK

TTC6

461

Q86TZ1
LCKEYENEDYFNKLI

NME8

361

Q8N427
DVCQLFKCYDVQLYK

RFX8

216

Q6ZV50
YSECLKINNKECAIY

SPAG1

646

Q07617
EAFAKQLCFQDQYVK

GEMIN5

966

Q8TEQ6
NDVLEVKRKYYKVNC

KCNJ16

311

Q9NPI9
LECYVRKDLVYTKAN

SPRED2

71

Q7Z698
KAGKYEQAIQCYTEA

TOMM70

126

O94826
LKVAAYAAQLEQYQK

NAPB

166

Q9H115
LINYYNRIKDSCVKA

SNX5

216

Q9Y5X3
KALEQKPDDAQYYCQ

SUGT1

36

Q9Y2Z0
LQQVAEKYYGNKCII

UAP1

146

Q16222
QEAVKYYEQDLALAK

TTC28

651

Q96AY4
EVAAYRNSYKKNICV

TTC29

56

Q8NA56
KQQELCDILVAYSAY

TBC1D28

166

Q2M2D7
CDVCKKLVDLYYQEK

TTC37

116

Q6PGP7
EYQIVHNGEKVYECK

ZFP14

161

Q9HCL3
YDYSNKLCKDAVLNK

UGT2B15

121

P54855
YVFLKYKRQVNECEA

TEX15

1781

Q9BXT5
KCYLDINALQELYQK

TTC39C

171

Q8N584
KDKYYNCNVVVQARL

THSD4

976

Q6ZMP0
LNYKVCLAEVYQDKA

GTF3C1

1331

Q12789
ADYEAYVKCQDKVSQ

PYGL

776

P06737
ECKECGKNYLSAYQL

ZNF283

236

Q8N7M2
QLAVYCVSLKKEYEN

TRAIP

196

Q9BWF2
KVCEEKLRYAAYNCV

HECTD3

836

Q5T447
YYVDVLDGKLACVNK

MUC12

5316

Q9UKN1
LYCKQDYQQLFAAKC

LMX1B

101

O60663
KCQELVSDVDYKNYL

NEB

2371

P20929
KKCQTLVSDVDYKNY

NEB

2856

P20929