Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF355P ZNF585A ZNF577 ZNF789 ZNF337 ZSCAN5A ZNF549 ZNF674 ZNF329 ZNF485 ZNF267 ZNF429 ZNF205 MYNN BCL11A ZNF519 ZNF658B ZNF595 ZNF551 ZNF546 ZNF585B LHX2 ZNF600 ZNF197 ZNF790 ZNF66 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF415 ZNF614 ZNF443 ZNF292 ZNF114

9.60e-15141214040GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF355P ZNF585A ZNF577 ZNF789 ZNF337 ZSCAN5A ZNF549 ZNF674 ZNF329 ZNF485 ZNF267 ZNF429 ZNF205 MYNN BCL11A ZNF519 ZNF658B ZNF595 ZNF551 HNRNPU ZNF546 ZNF585B LHX2 ZNF600 ZNF197 ZNF790 ZNF66 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF415 ZNF614 ZNF443 ZNF114

2.83e-14145914040GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF355P ZNF585A ZNF577 ZNF789 ZSCAN5A ZNF549 ZNF485 ZNF267 ZNF429 ZNF205 MYNN BCL11A ZNF519 ZNF658B ZNF595 ZNF551 HNRNPU ZNF546 ZNF585B LHX2 ZNF600 ZNF197 ZNF790 ZNF66 ZNF432 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF415 ZNF114

2.11e-11124414033GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF355P ZNF585A ZNF577 ZNF789 ZSCAN5A ZNF549 ZNF485 ZNF267 ZNF429 ZNF205 MYNN BCL11A ZNF519 ZNF658B ZNF595 ZNF551 HNRNPU ZNF546 ZNF585B LHX2 ZNF600 ZNF197 ZNF790 ZNF66 ZNF432 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF415 ZNF114

3.72e-11127114033GO:0000987
GeneOntologyMolecularFunctionmalate dehydrogenase (decarboxylating) (NADP+) activity

ME1 ME3

1.46e-0431402GO:0004473
GeneOntologyMolecularFunctiontransition metal ion binding

LMCD1 ZNF622 ZSWIM2 ZNF205 SIRT6 ME1 PPM1A BLM MEP1B PARP1 TIMM10 DNLZ ADAMTS9 EXD2 CSRP1 MME ZNF90 ZNF91 ZMYM3 MOCOS

2.39e-04118914020GO:0046914
GeneOntologyMolecularFunctionmalic enzyme activity

ME1 ME3

2.90e-0441402GO:0004470
GeneOntologyMolecularFunctionoxaloacetate decarboxylase activity

ME1 ME3

2.90e-0441402GO:0008948
GeneOntologyMolecularFunctiondamaged DNA binding

SIRT6 BLM PARP1 ZNF432 POLQ

3.12e-04841405GO:0003684
GeneOntologyMolecularFunctionzinc ion binding

LMCD1 ZNF622 ZSWIM2 ZNF205 SIRT6 BLM MEP1B PARP1 TIMM10 DNLZ ADAMTS9 CSRP1 MME ZNF90 ZNF91 ZMYM3

5.20e-0489114016GO:0008270
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

ZNF585A ZNF485 ZNF267 ZNF519 ZNF658B ZNF585B LHX2 ZNF600 ZNF197 ZNF615 ZNF91 ZNF292

5.91e-0456014012GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

ZNF585A ZNF485 ZNF267 ZNF519 ZNF658B ZNF585B LHX2 ZNF600 ZNF197 ZNF615 ZNF91 ZNF292

6.49e-0456614012GO:0001216
GeneOntologyMolecularFunctionDNA helicase activity

CHD1L BLM POLQ DNA2

9.42e-04621404GO:0003678
GeneOntologyMolecularFunctionmalate dehydrogenase activity

ME1 ME3

1.33e-0381402GO:0016615
DomainKRAB

ZNF585A ZNF577 ZNF789 ZNF337 ZNF549 ZNF674 ZNF485 ZNF267 ZNF429 ZNF205 ZNF519 ZNF595 ZNF551 ZNF546 ZNF585B ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF614 ZNF443 ZNF114

5.13e-2235813929PS50805
DomainKRAB

ZNF585A ZNF577 ZNF789 ZNF337 ZNF549 ZNF674 ZNF485 ZNF267 ZNF429 ZNF205 ZNF519 ZNF595 ZNF551 ZNF546 ZNF585B ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF614 ZNF443 ZNF114

5.13e-2235813929PF01352
DomainKRAB

ZNF585A ZNF577 ZNF789 ZNF337 ZNF549 ZNF674 ZNF485 ZNF267 ZNF429 ZNF205 ZNF519 ZNF595 ZNF551 ZNF546 ZNF585B ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF614 ZNF443 ZNF114

1.20e-2136913929SM00349
DomainKRAB

ZNF585A ZNF577 ZNF789 ZNF337 ZNF549 ZNF674 ZNF485 ZNF267 ZNF429 ZNF205 ZNF519 ZNF595 ZNF551 ZNF546 ZNF585B ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF614 ZNF443 ZNF114

1.29e-2137013929IPR001909
Domainzf-C2H2

ZNF585A ZNF577 ZNF789 ZNF337 ZSCAN5A ZNF549 ZNF674 ZNF329 ZNF485 ZNF267 ZNF429 ZNF205 MYNN BCL11A ZNF519 ZNF595 ZNF551 ZNF546 ZNF585B ZNF600 ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF415 ZNF614 ZNF443 ZNF292 ZNF114

9.25e-2169313936PF00096
Domain-

ZNF585A ZNF577 ZNF789 ZNF337 ZSCAN5A ZNF549 ZNF674 ZNF329 ZNF485 ZNF267 ZNF429 ZNF205 MYNN BCL11A ZNF519 ZNF551 ZNF546 ZNF585B ZNF600 ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF415 ZNF614 ZNF443 ZNF292 ZNF114

4.54e-20679139353.30.160.60
DomainZnf_C2H2/integrase_DNA-bd

ZNF585A ZNF577 ZNF789 ZNF337 ZSCAN5A ZNF549 ZNF674 ZNF329 ZNF485 ZNF267 ZNF429 ZNF205 MYNN BCL11A ZNF519 ZNF551 ZNF546 ZNF585B ZNF600 ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF415 ZNF614 ZNF443 ZNF292 ZNF114

9.15e-2069413935IPR013087
DomainZnf_C2H2

ZNF585A ZNF577 ZNF789 ZNF337 ZSCAN5A ZNF549 ZNF674 ZNF329 ZNF485 ZNF267 ZNF429 ZNF622 ZNF205 MYNN BCL11A ZNF519 ZNF595 ZNF551 ZNF546 ZNF585B ZNF600 ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF415 ZNF614 ZNF443 ZNF292 ZNF114

1.49e-1980513937IPR007087
DomainZnF_C2H2

ZNF585A ZNF577 ZNF789 ZNF337 ZSCAN5A ZNF549 ZNF674 ZNF329 ZNF485 ZNF267 ZNF429 ZNF622 ZNF205 MYNN BCL11A ZNF519 ZNF595 ZNF551 ZNF546 ZNF585B ZNF600 ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF415 ZNF614 ZNF443 ZNF292 ZNF114

1.68e-1980813937SM00355
DomainZINC_FINGER_C2H2_2

ZNF585A ZNF577 ZNF789 ZNF337 ZSCAN5A ZNF549 ZNF674 ZNF329 ZNF485 ZNF267 ZNF429 ZNF205 MYNN BCL11A ZNF519 ZNF595 ZNF551 ZNF546 ZNF585B ZNF600 ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF415 ZNF614 ZNF443 ZNF292 ZNF114

3.62e-1977513936PS50157
DomainZINC_FINGER_C2H2_1

ZNF585A ZNF577 ZNF789 ZNF337 ZSCAN5A ZNF549 ZNF674 ZNF329 ZNF485 ZNF267 ZNF429 ZNF205 MYNN BCL11A ZNF519 ZNF595 ZNF551 ZNF546 ZNF585B ZNF600 ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF415 ZNF614 ZNF443 ZNF292 ZNF114

3.94e-1977713936PS00028
DomainZnf_C2H2-like

ZNF585A ZNF577 ZNF789 ZNF337 ZSCAN5A ZNF549 ZNF674 ZNF329 ZNF485 ZNF267 ZNF429 ZNF622 ZNF205 MYNN BCL11A ZNF519 ZNF551 ZNF546 ZNF585B ZNF600 ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF415 ZNF614 ZNF443 ZNF292 ZNF114

8.62e-1979613936IPR015880
Domainzf-C2H2_6

ZNF789 ZNF549 ZNF329 ZNF267 ZNF429 MYNN ZNF551 ZNF546 ZNF600 ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF443 ZNF114

1.88e-1431413921PF13912
DomainEGF

STAB2 TECTA VWDE F9 MEP1B TMEFF1 NELL1 HMCN1 HABP2

6.73e-052351399SM00181
DomainEGF-like_dom

STAB2 TECTA VWDE F9 MEP1B TMEFF1 NELL1 HMCN1 HABP2

1.05e-042491399IPR000742
DomainLIM

LMCD1 LHX2 CSRP1 CSRP2 ABLIM2

1.63e-04691395PF00412
DomainMalic_OxRdtase

ME1 ME3

1.64e-0431392IPR001891
DomainMalic_NAD-bd

ME1 ME3

1.64e-0431392IPR012302
DomainMalic_N_dom

ME1 ME3

1.64e-0431392IPR012301
DomainMALIC_ENZYMES

ME1 ME3

1.64e-0431392PS00331
DomainMalic_M

ME1 ME3

1.64e-0431392PF03949
DomainMalic_M

ME1 ME3

1.64e-0431392SM00919
Domainmalic

ME1 ME3

1.64e-0431392PF00390
Domain-

ME1 ME3

1.64e-04313923.40.50.10380
Domainmalic

ME1 ME3

1.64e-0431392SM01274
DomainMalic_enzyme_CS

ME1 ME3

1.64e-0431392IPR015884
Domain-

LMCD1 LHX2 CSRP1 CSRP2 ABLIM2

1.74e-047013952.10.110.10
DomainLIM

LMCD1 LHX2 CSRP1 CSRP2 ABLIM2

1.86e-04711395SM00132
DomainZnf_LIM

LMCD1 LHX2 CSRP1 CSRP2 ABLIM2

1.86e-04711395IPR001781
DomainLIM_DOMAIN_1

LMCD1 LHX2 CSRP1 CSRP2 ABLIM2

1.86e-04711395PS00478
DomainLIM_DOMAIN_2

LMCD1 LHX2 CSRP1 CSRP2 ABLIM2

1.86e-04711395PS50023
DomainFAS1

STAB2 TGFBI

3.27e-0441392SM00554
DomainFAS1_domain

STAB2 TGFBI

3.27e-0441392IPR000782
DomainPIN_4

SWT1 SMG6

3.27e-0441392PF13638
Domain-

STAB2 TGFBI

3.27e-04413922.30.180.10
DomainFAS1

STAB2 TGFBI

3.27e-0441392PS50213
DomainFasciclin

STAB2 TGFBI

3.27e-0441392PF02469
DomainEGF

STAB2 TECTA F9 MEP1B HMCN1 HABP2

3.61e-041261396PF00008
DomainEGF_3

STAB2 VWDE F9 MEP1B TMEFF1 NELL1 HMCN1 HABP2

3.82e-042351398PS50026
DomainEGF_1

STAB2 VWDE F9 MEP1B TMEFF1 NELL1 HMCN1 HABP2

6.54e-042551398PS00022
DomainEGF-like_CS

STAB2 VWDE F9 MEP1B TMEFF1 NELL1 HMCN1 HABP2

7.62e-042611398IPR013032
DomainPIN_dom

SWT1 SMG6

8.09e-0461392IPR002716
DomainPINc

SWT1 SMG6

8.09e-0461392SM00670
DomainEGF_2

STAB2 VWDE F9 MEP1B TMEFF1 NELL1 HMCN1 HABP2

8.40e-042651398PS01186
DomainTSP_1

THSD7A HMCN1 ADAMTS9 ADAMTS16

1.25e-03631394PF00090
DomainTSP1

THSD7A HMCN1 ADAMTS9 ADAMTS16

1.40e-03651394SM00209
DomainTSP1_rpt

THSD7A HMCN1 ADAMTS9 ADAMTS16

1.40e-03651394IPR000884
DomainTSP1

THSD7A HMCN1 ADAMTS9 ADAMTS16

1.40e-03651394PS50092
DomainEGF_CA

STAB2 F9 NELL1 HMCN1 HABP2

2.19e-031221395SM00179
DomainEGF-like_Ca-bd_dom

STAB2 F9 NELL1 HMCN1 HABP2

2.36e-031241395IPR001881
DomainIG_FLMN

FLNB FLNC

2.38e-03101392SM00557
DomainFilamin

FLNB FLNC

2.89e-03111392PF00630
DomainGFP-like

STAB2 HMCN1

2.89e-03111392IPR023413
DomainFILAMIN_REPEAT

FLNB FLNC

2.89e-03111392PS50194
DomainFilamin/ABP280_rpt

FLNB FLNC

2.89e-03111392IPR001298
DomainFilamin/ABP280_repeat-like

FLNB FLNC

2.89e-03111392IPR017868
Domain-

STAB2 HMCN1

2.89e-031113922.40.155.10
Domain-

MEP1B ADAMTS9 ADAMTS16 MME

3.14e-038113943.40.390.10
DomainMetalloPept_cat_dom

MEP1B ADAMTS9 ADAMTS16 MME

3.14e-03811394IPR024079
DomainEGF_dom

STAB2 NELL1

3.46e-03121392IPR024731
Domain-

SWT1 SMG6

3.46e-031213923.40.50.1010
DomainEGF_3

STAB2 NELL1

3.46e-03121392PF12947
DomainIMPORTIN_B_NT

IPO13 XPO7

4.72e-03141392PS50166
DomainPIN_domain-like

SWT1 SMG6

4.72e-03141392IPR029060
DomainIBN_N

IPO13 XPO7

5.42e-03151392PF03810
DomainVWF_type-D

TECTA VWDE

6.16e-03161392IPR001846
DomainIBN_N

IPO13 XPO7

6.16e-03161392SM00913
DomainVWFD

TECTA VWDE

6.16e-03161392PS51233
DomainVWD

TECTA VWDE

6.16e-03161392SM00216
DomainVWD

TECTA VWDE

6.16e-03161392PF00094
DomainZINC_PROTEASE

MEP1B ADAMTS9 ADAMTS16 MME

6.19e-03981394PS00142
Domainzf-RING_2

ZSWIM2 RNF6 RLIM

6.83e-03521393PF13639
DomainImportin-beta_N

IPO13 XPO7

6.95e-03171392IPR001494
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ZNF585A ZNF577 ZNF337 ZNF549 ZNF485 ZNF267 ZNF429 ZNF205 ZNF519 ZNF595 PPM1A ZNF551 ZNF546 ZNF585B BLM PCGF6 PARP1 ZNF600 ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 DNA2 ZNF439 CDC27 ZNF415 ZNF614 ZNF443 FKBP5 ZNF114

5.04e-10138710934M734
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF789 ZNF485 ZNF267 ZNF595 ZNF197 ZNF432 ZNF620 ZNF615 ZNF90 ZNF91 ZNF614

2.47e-101811421137372979
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF355P ZNF585A ZNF429 MYNN ZNF585B ZNF616 ZNF91

1.21e-094914279630514
Pubmed

Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.

ZNF355P ZNF429 ZNF595 ZNF91

3.51e-0715142415885501
Pubmed

Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.

FLNB FLNC HNRNPU PARP1 PRKDC

1.27e-0646142533403043
Pubmed

Tagging genes with cassette-exchange sites.

FLNB LEMD3 RPS6KA1 ENC1 ZNF429 ZNF622 CIT ZNF595 ZNF292 SMG6

1.30e-063351421015741177
Pubmed

The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons.

ZNF355P ZNF429 ZNF595

1.32e-066142330846446
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF355P ZNF429 ZNF595 ZNF91

5.84e-0629142414563677
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZSCAN5A ZNF429 ZNF622 ZNF205 MYNN MLLT10 ZNF595 CSRP1 CSRP2 ZNF790 ZNF616 ZNF91 ABLIM2 ZNF292

6.16e-068081421420412781
Pubmed

Isolated parkinsonism is an atypical presentation of GRN and C9orf72 gene mutations.

GRN C9orf72

1.66e-052142232961397
Pubmed

DNA damage-induced inhibition of rRNA synthesis by DNA-PK and PARP-1.

PARP1 PRKDC

1.66e-052142223775790
Pubmed

Profiling of ubiquitination pathway genes in peripheral cells from patients with frontotemporal dementia due to C9ORF72 and GRN mutations.

GRN C9orf72

1.66e-052142225580532
Pubmed

Adaptive and Constitutive Activations of Malic Enzymes Confer Liver Cancer Multilayered Protection Against Reactive Oxygen Species.

ME1 ME3

1.66e-052142233619771
Pubmed

Functional roles of the tetramer organization of malic enzyme.

ME1 ME3

1.66e-052142219416979
Pubmed

A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.

FLNB FLNC

1.66e-05214229694715
Pubmed

The chromatin remodeler ALC1 underlies resistance to PARP inhibitor treatment.

CHD1L PARP1

1.66e-052142233355125
Pubmed

Interaction of hepatitis B virus X protein with PARP1 results in inhibition of DNA repair in hepatocellular carcinoma.

SIRT6 PARP1

1.66e-052142227041572
Pubmed

Effects of novel inhibitors of poly(ADP-ribose) polymerase-1 and the DNA-dependent protein kinase on enzyme activities and DNA repair.

PARP1 PRKDC

1.66e-052142215286704
Pubmed

Multiple roles for PARP1 in ALC1-dependent nucleosome remodeling.

CHD1L PARP1

1.66e-052142234465625
Pubmed

PARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis.

PARP1 PRKDC

1.66e-052142222614020
Pubmed

CHD1L: a new candidate gene for congenital anomalies of the kidneys and urinary tract (CAKUT).

CHD1L PARP1

1.66e-052142222146311
Pubmed

Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease.

ZNF585A ZNF585B

1.66e-052142237668106
Pubmed

Germline mutation rates at tandem repeat loci in DNA-repair deficient mice.

PARP1 PRKDC

1.66e-052142215450426
Pubmed

Recurrent deletions in clonal hematopoiesis are driven by microhomology-mediated end joining.

PARP1 POLQ

1.66e-052142233911081
Pubmed

hnRNP-U is a specific DNA-dependent protein kinase substrate phosphorylated in response to DNA double-strand breaks.

HNRNPU PRKDC

1.66e-052142219351595
Pubmed

Activation of the SNF2 family ATPase ALC1 by poly(ADP-ribose) in a stable ALC1·PARP1·nucleosome intermediate.

CHD1L PARP1

1.66e-052142223132853
Pubmed

PhagoStat a scalable and interpretable end to end framework for efficient quantification of cell phagocytosis in neurodegenerative disease studies.

GRN C9orf72

1.66e-052142238499658
Pubmed

The limits of promiscuity: isoform-specific dimerization of filamins.

FLNB FLNC

1.66e-052142212525170
Pubmed

Neuroimmune dysfunction in frontotemporal dementia: Insights from progranulin and C9orf72 deficiency.

GRN C9orf72

1.66e-052142235792478
Pubmed

Analysis of gene expression and methylation datasets identified ADAMTS9, FKBP5, and PFKBF3 as biomarkers for osteoarthritis.

ADAMTS9 FKBP5

1.66e-052142230317616
Pubmed

A pathogenic progranulin mutation and C9orf72 repeat expansion in a family with frontotemporal dementia.

GRN C9orf72

1.66e-052142224286341
Pubmed

An RNF12-USP26 amplification loop drives germ cell specification and is disrupted by disease-associated mutations.

USP26 RLIM

1.66e-052142235857630
Pubmed

Impact of PARP-1 and DNA-PK expression on survival in patients with glioblastoma multiforme.

PARP1 PRKDC

1.66e-052142221775006
Pubmed

Plasma Small Extracellular Vesicles with Complement Alterations in GRN/C9orf72 and Sporadic Frontotemporal Lobar Degeneration.

GRN C9orf72

1.66e-052142235159297
Pubmed

Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence.

SIRT6 PARP1

1.66e-052142222753495
Pubmed

CHD1L Regulated PARP1-Driven Pluripotency and Chromatin Remodeling During the Early-Stage Cell Reprogramming.

CHD1L PARP1

1.66e-052142226201266
Pubmed

Loss of the serum response factor cofactor, cysteine-rich protein 1, attenuates neointima formation in the mouse.

CSRP1 CSRP2

1.66e-052142220056913
Pubmed

Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis.

PARP1 PRKDC

1.66e-05214229398855
Pubmed

Synergistic inhibition of PARP-1 and NF-κB signaling downregulates immune response against recombinant AAV2 vectors during hepatic gene therapy.

F9 PARP1

1.66e-052142226443873
Pubmed

[Clinical Significance of Thrombospondin Type 1 Domain-Containing 7A and Neural Epidermal Growth Factor-Like 1 Protein in M-Type Phospholipase A2 Receptor-Negative Membranous Nephropathy].

THSD7A NELL1

1.66e-052142237157070
Pubmed

Suppression of the poly(ADP-ribose) polymerase activity by DNA-dependent protein kinase in vitro.

PARP1 PRKDC

1.66e-052142210467406
Pubmed

Disrupted myelin lipid metabolism differentiates frontotemporal dementia caused by GRN and C9orf72 gene mutations.

GRN C9orf72

1.66e-052142236967384
Pubmed

ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance.

PARP1 ZNF432

1.66e-052142237823600
Pubmed

SIRT6 promotes DNA repair under stress by activating PARP1.

SIRT6 PARP1

1.66e-052142221680843
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

USP36 LEMD3 ZSCAN5A DLGAP5 RPS12 ZNF205 CHD1L JMJD1C NDUFS6 HNRNPU BLM PCGF6 PARP1 SETD2 PRKDC CDC27 ZMYM3

2.27e-0512941421730804502
Pubmed

Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2.

FLNB FLNC DCAF6 LMCD1

2.40e-0541142418157088
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

USP36 DLGAP5 CIT BLM TNFAIP1 PRKDC CDC27

2.64e-05210142716565220
Pubmed

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.

ZNF585A ZNF429 ZNF595 F9 HNRNPU ZNF585B TGFBI DNA2

2.85e-05292142812819125
Pubmed

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1.

CHD1L PARP1 PRKDC

2.92e-0515142319661379
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

FLNC LEMD3 ZNF329 ZNF485 ZNF205 GRN JMJD1C NDUFS6 ZNF551 HNRNPU BLM PARP1 PRKDC ZMYM3 VDAC2 XPO7

3.47e-0512031421629180619
Pubmed

Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.

ZNF90 ZNF91 ZNF114

3.59e-051614238467795
Pubmed

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler.

CHD1L PARP1 PRKDC

3.59e-0516142319666485
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

THSD7A CUL7 CLSTN1 JMJD1C SETD2 ADAMTS9 ADAMTS16 ZNF616 MINAR1 MBD5

3.75e-054931421015368895
Pubmed

An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.

FLNB FLNC RPS12 GRN RRM1 HNRNPU PARP1 PRKDC VDAC2

3.95e-05397142921319273
Pubmed

Candidate genes and their regulatory elements: alcohol preference and tolerance.

FLNB ZNF267 ZNF519

4.35e-0517142316783646
Pubmed

Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics.

ZNF432 ZNF614

4.95e-053142224280104
Pubmed

Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics.

GRN C9orf72

4.95e-053142222366795
Pubmed

Clinical features of TBK1 carriers compared with C9orf72, GRN and non-mutation carriers in a Belgian cohort.

GRN C9orf72

4.95e-053142226674655
Pubmed

Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated With MAPT, GRN, and C9orf72 Pathogenic Variants.

GRN C9orf72

4.95e-053142233112398
Pubmed

Defining the association of TMEM106B variants among frontotemporal lobar degeneration patients with GRN mutations and C9orf72 repeat expansions.

GRN C9orf72

4.95e-053142225085782
Pubmed

Analyses MAPT, GRN, and C9orf72 mutations in Chinese patients with frontotemporal dementia.

GRN C9orf72

4.95e-053142227311648
Pubmed

Human DNA2 possesses a cryptic DNA unwinding activity that functionally integrates with BLM or WRN helicases.

BLM DNA2

4.95e-053142227612385
Pubmed

DNA-PKcs and PARP1 Bind to Unresected Stalled DNA Replication Forks Where They Recruit XRCC1 to Mediate Repair.

PARP1 PRKDC

4.95e-053142226603896
Pubmed

Genetic screen in a large series of patients with primary progressive aphasia.

GRN C9orf72

4.95e-053142230599136
Pubmed

DNA2 cooperates with the WRN and BLM RecQ helicases to mediate long-range DNA end resection in human cells.

BLM DNA2

4.95e-053142225122754
Pubmed

JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks.

SIRT6 PARP1

4.95e-053142227568560
Pubmed

Distinct clinical and pathological phenotypes in frontotemporal dementia associated with MAPT, PGRN and C9orf72 mutations.

GRN C9orf72

4.95e-053142226473392
Pubmed

Patterns of regional cerebellar atrophy in genetic frontotemporal dementia.

GRN C9orf72

4.95e-053142226977398
Pubmed

DNA repair proteins cooperate with SOX2 in regulating the transition of human embryonic stem cells to neural progenitor cells.

PARP1 PRKDC

4.95e-053142234852960
Pubmed

Distinct clinical characteristics of C9orf72 expansion carriers compared with GRN, MAPT, and nonmutation carriers in a Flanders-Belgian FTLD cohort.

GRN C9orf72

4.95e-053142223338682
Pubmed

Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.

FLNB FLNC

4.95e-053142212393796
Pubmed

Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling.

CHD1L PARP1

4.95e-053142234874266
Pubmed

Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis.

SIRT6 PARP1

4.95e-053142234731617
Pubmed

Clinical and genetic analysis of MAPT, GRN, and C9orf72 genes in Korean patients with frontotemporal dementia.

GRN C9orf72

4.95e-053142224387985
Pubmed

Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.

FLNB FLNC

4.95e-053142211153914
Pubmed

The frontotemporal dementias.

GRN C9orf72

4.95e-053142225998110
Pubmed

The PINK1 p.Asn521Thr Variant Is Associated with Earlier Disease Onset in GRN/C9orf72 Frontotemporal Lobar Degeneration.

GRN C9orf72

4.95e-053142236361641
Pubmed

Differences in Motor Features of C9orf72, MAPT, or GRN Variant Carriers With Familial Frontotemporal Lobar Degeneration.

GRN C9orf72

4.95e-053142235790423
Pubmed

Plasma phosphorylated TDP-43 levels are elevated in patients with frontotemporal dementia carrying a C9orf72 repeat expansion or a GRN mutation.

GRN C9orf72

4.95e-053142224309270
Pubmed

PARP1 negatively regulates transcription of BLM through its interaction with HSP90AB1 in prostate cancer.

BLM PARP1

4.95e-053142237415147
Pubmed

Filamins as integrators of cell mechanics and signalling.

FLNB FLNC

4.95e-053142211252955
Pubmed

Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs.

PARP1 PRKDC

4.95e-053142215545322
Pubmed

Abnormal pain perception is associated with thalamo-cortico-striatal atrophy in C9orf72 expansion carriers in the GENFI cohort.

GRN C9orf72

4.95e-053142232759310
Pubmed

UV-induced RPA phosphorylation is increased in the absence of DNA polymerase eta and requires DNA-PK.

PRKDC POLQ

4.95e-053142216520097
Pubmed

PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1.

CHD1L PARP1

4.95e-053142223045548
Pubmed

Early symptoms in symptomatic and preclinical genetic frontotemporal lobar degeneration.

GRN C9orf72

4.95e-053142232769115
Pubmed

Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS.

PARP1 PRKDC

4.95e-053142235460603
Pubmed

The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones.

RNF6 RLIM

4.95e-053142216204183
Pubmed

Distinct Neuroanatomical Correlates of Neuropsychiatric Symptoms in the Three Main Forms of Genetic Frontotemporal Dementia in the GENFI Cohort.

GRN C9orf72

4.95e-053142230010122
Pubmed

p53 deficiency does not affect mutation rate in the mouse germline.

PARP1 PRKDC

4.95e-053142215806156
Pubmed

Dominant frontotemporal dementia mutations in 140 cases of primary progressive aphasia and speech apraxia.

GRN C9orf72

4.95e-053142225765123
Pubmed

Development and validation of pedigree classification criteria for frontotemporal lobar degeneration.

GRN C9orf72

4.95e-053142224081456
Pubmed

Mutation Frequency of the Major Frontotemporal Dementia Genes, MAPT, GRN and C9ORF72 in a Turkish Cohort of Dementia Patients.

GRN C9orf72

4.95e-053142227632209
Pubmed

CPP32/Yama/apopain cleaves the catalytic component of DNA-dependent protein kinase in the holoenzyme.

PARP1 PRKDC

4.95e-05314228804412
Pubmed

Hippocampal Subfield Volumetry: Differential Pattern of Atrophy in Different Forms of Genetic Frontotemporal Dementia.

GRN C9orf72

4.95e-053142229889066
Pubmed

NAD+-mediated regulation of mammalian base excision repair.

SIRT6 PARP1

4.95e-053142233087267
Pubmed

RNF12 catalyzes BRF1 ubiquitination and regulates RNA polymerase III-dependent transcription.

FLNB HNRNPU PARP1 RLIM

5.30e-0550142430413534
Pubmed

Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance.

USP36 PARP1 PRKDC

6.15e-0519142334188037
Pubmed

Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.

ZNF355P ZNF429 ZNF595

7.22e-052014237479878
Pubmed

Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.

ZNF355P ZNF429 ZNF595

7.22e-052014232542606
Pubmed

A digenic cause of cleft lip in A-strain mice and definition of candidate genes for the two loci.

ZNF429 ADAMTS16 CDC27

7.22e-0520142315329828
InteractionCBX5 interactions

ZNF585A CHD1L CUL7 CIT HNRNPU ZNF585B PCGF6 PARP1 SETD2 ZNF620 MBD5 ZMYM3 ZNF292 ZNF114

1.95e-0735614014int:CBX5
InteractionTRIM28 interactions

USP36 ZNF789 ZNF674 ZNF485 ZNF267 ZNF622 SIRT6 CUL7 CIT ZNF595 HNRNPU ZNF585B PCGF6 PARP1 ZNF600 ZNF197 ZNF432 ZNF620 ZNF616 ZNF615 PRKDC ZNF30 ZNF90 ZNF91 C9orf72 ZNF614 ZNF443 FKBP5 ZNF114

2.68e-07147414029int:TRIM28
InteractionH2AZ1 interactions

USP36 MIER3 CHD1L SIRT6 CIT JMJD1C PARP1 RLIM PRKDC C9orf72 CDC27 ZMYM3

1.12e-0537114012int:H2AZ1
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF585A ZNF577 ZSCAN5A ZNF549 ZNF329 ZNF551 ZNF546 ZNF585B ZNF600 CD22 LYPD5 ZNF790 ZNF432 ZNF616 ZNF528 ZNF615 ZNF30 ZNF415 ZNF614 ZNF114

9.30e-10119214220chr19q13
Cytoband19q13.41

ZNF577 ZNF600 ZNF432 ZNF616 ZNF615 ZNF614

1.68e-0778142619q13.41
Cytoband19q13.43

ZSCAN5A ZNF549 ZNF329 ZNF551

1.60e-0487142419q13.43
CytobandXq13.1

GCNA NALF2 ZMYM3

4.52e-04481423Xq13.1
CytobandEnsembl 112 genes in cytogenetic band chr19p12

ZNF429 ZNF66 ZNF90 ZNF91

5.81e-041221424chr19p12
Cytoband19q13.12

ZNF585A ZNF585B ZNF790

1.48e-0372142319q13.12
CytobandEnsembl 112 genes in cytogenetic band chrXq13

GCNA RLIM NALF2 ZMYM3

1.78e-031651424chrXq13
Cytoband19p12

ZNF66 ZNF90 ZNF91

2.80e-0390142319p12
Cytoband7p21.3

THSD7A VWDE

3.41e-032814227p21.3
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF585A ZNF577 ZNF789 ZNF337 ZSCAN5A ZNF549 ZNF674 ZNF329 ZNF485 ZNF267 ZNF429 ZNF205 MYNN BCL11A ZNF519 ZNF595 ZNF551 ZNF546 ZNF585B ZNF600 ZNF197 ZNF790 ZNF432 ZNF620 ZNF616 ZNF528 ZNF615 ZNF30 ZNF90 ZNF91 ZNF439 ZNF415 ZNF614 ZNF443 ZNF292 ZNF114

8.68e-247181093628
GeneFamilyLIM domain containing

LMCD1 CSRP1 CSRP2 ABLIM2

4.41e-045910941218
CoexpressionAtlasdev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_200

SEMA7A ME1 TGFBI NELL1 ADAMTS9 ADAMTS16 FKBP5 ZMYM3

1.70e-051771348gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_200
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NOG ENC1 CXCL14 RRM1 CIT BLM POLQ DNA2 FST

1.25e-081931429516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LMCD1 ENC1 CXCL14 ZNF519 RRM1 CIT BLM POLQ DNA2

1.30e-081941429590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NOG LMCD1 ENC1 CXCL14 ZNF519 TGFBI CSRP1 UNC13C

1.25e-071811428d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ZNF519 RRM1 CIT BLM PARP1 PRKDC POLQ DNA2

2.20e-071951428cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCellE17.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NOG LMCD1 ENC1 BCL11A TMEFF1 TGFBI CSRP2 FKBP5

2.20e-0719514281daddd801bd4596fffbdb822fc326d5127c96004
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ZNF519 RRM1 CIT BLM PARP1 PRKDC POLQ DNA2

2.29e-071961428df366d76ea55f49e349d622effa57c1535df8400
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|356C / Donor, Lineage, Cell class and subclass (all cells)

ZNF674 LYPD5 ZNF616 MME POLQ ZMYM3 MOCOS

9.11e-0716214277d43d59531cbefe3ac94953b7faf7156b2a31441
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ZNF585A ZNF577 ENC1 ZNF485 ADCY9 LLGL1 ZNF528

1.77e-0617914275be883d7d0be3180bb9844e4a757f0dd247294e4
ToppCell(7)_DC_plasmacytoid|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

FLNB GRN BCL11A TGFBI NELL1 SLC15A4 CD36

2.06e-0618314272c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

DLGAP5 BCL11A CIT BLM CD22 POLQ DNA2

2.21e-0618514279766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLNC NOG LMCD1 ENC1 CXCL14 TGFBI CSRP1

2.46e-061881427c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RRM1 CIT BLM SEMA6D POLQ DNA2 FST

2.64e-061901427e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NOG LMCD1 ENC1 PCDHAC1 CXCL14 SEMA6D CSRP1

2.82e-0619214277ae3e1ca8bfc078c0e12a1595ecb0e343dab5d2f
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ENC1 CXCL14 RRM1 CIT BLM POLQ DNA2

2.92e-061931427bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

THSD7A SEMA7A PDGFRL LMCD1 HMCN1 ADAMTS16 FST

2.92e-061931427194e7fa00a50cc4e026987b715323d125d79594e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ZNF519 RRM1 CIT BLM ZNF90 POLQ DNA2

3.13e-061951427b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCellE17.5-Mesenchymal-myocytic_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NOG PDGFRL LMCD1 ENC1 TMEFF1 TGFBI CSRP2

3.13e-06195142701a750d660993017af00736215cbcff2de5909c1
ToppCellFibroblast-B_(Myofibroblast)|World / shred on cell class and cell subclass (v4)

PDGFRL LMCD1 ENC1 TGFBI HMCN1 CSRP2 FST

3.13e-061951427a8d6416518f226e1ec2d6bdc9d4b90cef5cb1365
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ZNF519 RRM1 CIT BLM ZNF90 POLQ DNA2

3.13e-06195142756d8734d020b3da08a5aa9e67999706a9e023a99
ToppCell11.5-Distal-Mesenchymal-Airway_Smooth_Muscle|Distal / Age, Tissue, Lineage and Cell class

NOG LMCD1 ENC1 CXCL14 BCL11A TGFBI SEMA6D

3.24e-06196142705530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCellCOVID-19-Myeloid-Migratory_DC|Myeloid / Condition, Lineage and Cell class

ANO9 SEMA7A PDGFRL LMCD1 DIPK1A BCL11A CSRP2

3.46e-06198142790f3b227cbc61c268d6d94bc9945a08d83d2d3d5
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate|2m / Sample Type, Dataset, Time_group, and Cell type.

THSD7A PIK3R3 ENC1 BCL11A LHX2 ZNF91 ZNF292

3.70e-0620014272a635694844ddabcd98462c5636a6f41a3f08a46
ToppCellPBMC-Mild-cDC_4|Mild / Compartment, Disease Groups and Clusters

ZNF585A SWT1 DIPK1A ZNF674 MIER3 ZNF485

4.38e-061331426e53fbd69775a4bff61de82557342f7ac80915c4d
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma-5|TCGA-Endometrium / Sample_Type by Project: Shred V9

ZNF519 TECTA CLDN6 TMEFF1 ADAMTS16 ZNF439

1.14e-05157142659450e9f580555091b159fbbe0a0756e51bcd9ad
ToppCellCV-Mild-4|Mild / Virus stimulation, Condition and Cluster

SEMA7A CIT TGFBI MINAR1 POLQ DNA2

1.26e-0516014262e24f8de5086b086863d3bf4d9afbd9bc93f4d5e
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|356C / Donor, Lineage, Cell class and subclass (all cells)

FLNC STAB2 ADAMTS9 LYPD5 CSRP2 ABLIM2

1.56e-0516614265ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|356C / Donor, Lineage, Cell class and subclass (all cells)

FLNC STAB2 ADAMTS9 LYPD5 CSRP2 ABLIM2

1.56e-0516614266bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCellASK452-Endothelial-Lymphatic|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

STAB2 ZNF485 ZNF595 CD36 IPO13 ZNF415

2.17e-051761426b4d280ecc07701d526f50d44c45ea91b3eeb00b1
ToppCellILEUM-inflamed-(3)_pDC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FLNB SEMA7A GRN BCL11A TGFBI SLC15A4

2.17e-051761426b9f847dd55703e413f3cd815eef5724fffaf13b3
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNB THSD7A LMCD1 PIK3R3 CIT ADAMTS9

2.54e-051811426136b0c60680068838d184d32aa99d7bea8718dbc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ME3 NELL1 SEMA6D HMCN1 ADAMTS16 UNC13C

2.62e-0518214265f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellE18.5-samps-Mesenchymal-Myofibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

NOG PDGFRL LMCD1 ENC1 BCL11A TGFBI

2.70e-051831426de08f9ea02b7244d5a8788064631d10f06565337
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ME3 NELL1 SEMA6D HMCN1 ADAMTS16 UNC13C

2.70e-0518314262e831a4d99c6f983793df71c0994124c943c6da9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 HMCN1 ADAMTS16 UNC13C DNAH9 HYDIN

2.78e-0518414262cbed6462fea2622871bb7e49b0df3d984239281
ToppCellCOPD-Stromal-Pericyte|COPD / Disease state, Lineage and Cell class

LMCD1 TRPC4 ADAMTS9 CSRP2 ABLIM2 FST

2.78e-051841426a56264a22dfc2d3672b20134ab7c3c7c23da5ae1
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNC LMCD1 TRPC4 CSRP1 SEL1L2 FST

2.78e-05184142654e5b63f55b8d6eccad53d389ea9c78f991e1414
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 HMCN1 ADAMTS16 UNC13C DNAH9 HYDIN

2.78e-051841426ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 HMCN1 ADAMTS16 UNC13C DNAH9 HYDIN

2.78e-0518414262b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNC LMCD1 TRPC4 CSRP1 SEL1L2 FST

2.78e-0518414267b5678718719020b52e7c2a7bd9797987defd7ff
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLNC LMCD1 TGFBI SEMA6D ADAMTS9 CSRP2

2.87e-051851426e58a009aaf342be019a909747b1895d5987d4daf
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CIT PCGF6 LYPD5 ZNF615 DNA2 XPO7

2.96e-051861426799903b68bc6f6205d004b44c603424b0d5f7c32
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

CIT PCGF6 LYPD5 ZNF615 DNA2 XPO7

2.96e-0518614265cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NOG LMCD1 ENC1 CXCL14 TGFBI SEMA6D

3.05e-051871426387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ME3 NELL1 SEMA6D HMCN1 ADAMTS16 UNC13C

3.14e-051881426eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NOG LMCD1 ENC1 CXCL14 SEMA6D FST

3.14e-0518814263004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ME3 NELL1 SEMA6D HMCN1 ADAMTS16 UNC13C

3.23e-051891426977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNB NELL1 SEMA6D HMCN1 ADAMTS16 UNC13C

3.23e-051891426e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNB THSD7A SEMA7A NELL1 HMCN1 CSRP2

3.23e-051891426360f09f46231a83f99d8fa0158b72a38068e1642
ToppCellP07|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PDGFRL LMCD1 TGFBI HMCN1 CSRP1 TNFAIP1

3.33e-05190142638a613a9bca0ba040c3ada00286d1ce6f83ab23a
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

DLGAP5 CIT BLM POLQ DNA2 FKBP5

3.33e-051901426d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ME3 NELL1 SEMA6D HMCN1 ADAMTS16 UNC13C

3.33e-051901426e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNB THSD7A PIK3R3 HMCN1 ADAMTS9 CD36

3.53e-0519214260aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCellE15.5-Mesenchymal-myocytic_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NOG ENC1 TMEFF1 TGFBI CSRP1 CSRP2

3.64e-0519314263316d6a39abb6a518d45b846254325fc7a8b2035
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NOG LMCD1 ENC1 CXCL14 TGFBI SEMA6D

3.64e-051931426000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NOG LMCD1 ENC1 CXCL14 TGFBI SEMA6D

3.64e-0519314262f203f6f0c2135acb046c9351a633c3b5b254a46
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

DLGAP5 ZNF519 CIT BLM POLQ DNA2

3.64e-0519314264b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellE15.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NOG ENC1 TMEFF1 TGFBI CSRP1 CSRP2

3.64e-051931426e787e618f6e8a1e22be366ce606bf78831b60a90
ToppCellIPF-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

TRPC4 SEMA6D ADAMTS9 CD36 CSRP2 ABLIM2

3.74e-0519414263892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DLGAP5 RRM1 CIT BLM POLQ DNA2

3.74e-051941426f9070035553bc68106a9e0bdf4b507715a138aba
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NOG LMCD1 ENC1 CXCL14 TGFBI SEMA6D

3.74e-05194142667f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNB LMCD1 SEMA6D HMCN1 CD36 CSRP2

3.85e-0519514260c15be3e7c238e329505dcbbe197a977d1019d45
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

DLGAP5 RRM1 CIT BLM POLQ DNA2

3.85e-051951426764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DLGAP5 RRM1 CIT BLM POLQ DNA2

3.85e-051951426926eb3fc5d028be936885bea0654a77db3107234
ToppCellHealthy/Control-T/NK_proliferative|Healthy/Control / Disease group and Cell class

DLGAP5 RRM1 CIT POLQ DNA2 HYDIN

3.85e-051951426957458fdc39723f4a31bd7fd3ce32891aa3fd462
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNB LMCD1 SEMA6D HMCN1 CD36 CSRP2

3.85e-05195142645ac0fdbeb0982d798c613a6d15715d725608aa9
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNB LMCD1 SEMA6D HMCN1 CD36 CSRP2

3.85e-0519514265b1f04a745467876b09113ee17ababd3fcf9fb01
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DLGAP5 RRM1 CIT BLM POLQ DNA2

3.85e-0519514261a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCell(01)_IL1RL1+-(1)_GFP|(01)_IL1RL1+ / shred by cell type by condition

RPS6KA1 CXCL14 GRN TGFBI FST FKBP5

3.96e-051961426b598b1112242534e139318012b257ed3cb09da83
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DLGAP5 RRM1 CIT BLM POLQ DNA2

3.96e-0519614261d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DLGAP5 RRM1 CIT BLM POLQ DNA2

3.96e-0519614261964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCellfacs-Skin-Telogen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB ENC1 TGFBI LHX2 HMCN1 FST

3.96e-051961426c936014125b2ed5f796221b74acb77b8f8359875
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DLGAP5 RRM1 CIT BLM POLQ DNA2

3.96e-05196142673f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellMatrixFB-Fibroblast-B_(Myofibroblast)|MatrixFB / shred on cell class and cell subclass (v4)

LMCD1 ENC1 TGFBI HMCN1 CSRP2 FST

3.96e-05196142638ea0eaf42f95c321ca23570d0d7752980cf00f8
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DLGAP5 RRM1 CIT BLM POLQ DNA2

4.08e-05197142684ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DLGAP5 RRM1 CIT BLM POLQ DNA2

4.08e-0519714268b616cde333bdbc0c591035ad9e4949155866245
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LMCD1 SEMA6D CSRP2 ADAMTS16 MME MOCOS

4.08e-0519714266668f0da54f3bf96769275e668cd57e00b8a5ef9
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDGFRL LMCD1 ENC1 TGFBI HMCN1 FST

4.08e-051971426090a251194da3e2806989d9a522588f83f52da7f
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LMCD1 SEMA6D CSRP2 ADAMTS16 MME MOCOS

4.08e-0519714267c275a2ac24a9a4f83fceda93a067e754837102f
ToppCell(5)_Dendritic_cell-(54)_pDC|(5)_Dendritic_cell / shred on Cell_type and subtype

FLNB SEMA7A ZNF329 BCL11A NELL1 SLC15A4

4.19e-051981426fc6c6b60dddd7f2f997af0f87fae33f1c23f34a8
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDGFRL LMCD1 ENC1 TGFBI HMCN1 CSRP2

4.19e-051981426a699b365d3b6149f13f02b2e2ae9b6fdce761848
ToppCellMS-IIF-Myeloid-pDC|IIF / Disease, condition lineage and cell class

FLNB SEMA7A GRN BCL11A TGFBI SLC15A4

4.31e-051991426e262ee854e64d87460bee810c14d6cbe744460e8
ToppCellT_cells-CCR7+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

USP36 RPS12 JMJD1C HNRNPU C9orf72 FKBP5

4.31e-051991426467820d6abe3024d9d655b9672c2f9cdc1303db3
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-dn_T|Leuk-UTI / Disease, condition lineage and cell class

ZSCAN5A PIK3R3 CUL7 RRM1 ZNF66 RAB37

4.31e-051991426aa4d8ce8994e5032a33d5cc68c482882147cdc3b
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DLGAP5 CIT ZNF551 BLM POLQ DNA2

4.31e-0519914261d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FLNB FLNC NOG THSD7A PIK3R3 ADAMTS9

4.31e-0519914266a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass

ZNF329 ME1 ME3 ZNF616 ZNF614 ZNF443

4.31e-051991426fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCellMS-Multiple_Sclerosis-Lymphocyte-T/NK-T/NK_proliferative|Multiple_Sclerosis / Disease, condition lineage and cell class

LMCD1 DLGAP5 RRM1 CIT POLQ DNA2

4.43e-0520014267faf1e37364203a08d2b2544979e848b41e36b1c
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DLGAP5 ZNF519 RRM1 CIT BLM POLQ

4.43e-052001426af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCellBL-critical-LOC-Lymphoid-Treg|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DLGAP5 RRM1 CIT BLM POLQ DNA2

4.43e-05200142604d95a9102248e98eed069840ea6d3d23a243fd5
ToppCelldroplet-Skin-nan-21m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOG LMCD1 LHX2 HMCN1 MME FST

4.43e-05200142669295705fc614c2687f2b6c8e6aa0c6717841008
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-NK_CD56bright|ICU-NoSEP / Disease, condition lineage and cell class

ANO9 ZNF577 ZNF485 ADCY9 ZNF528 ZNF614

4.43e-052001426c2df917900872453ea17a39928e39d071a6d3339
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal|GW12 / Sample Type, Dataset, Time_group, and Cell type.

ZNF337 ZNF585B TGFBI RNF6 TNFAIP1 MOCOS

4.43e-052001426be83f442179ba4217d12f0458059586ff3130991
ToppCell(54)_pDC|World / shred on Cell_type and subtype

FLNB SEMA7A TGFBI NELL1 SLC15A4 CD36

4.82e-052031426b8ba3e51770ff7b45cd02472f3e63aa4d5816f6f
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

NOG LMCD1 ENC1 TMEFF1 TGFBI

8.08e-0513814258d70e64843f7c3be8ee4203cc126fdf1001f0df5
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THSD7A TRPC4 CXCL14 NELL1 MME

8.36e-0513914259e9f29f92dbe65b26cc78b3a1c00778c6a701f5b
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_A|E18.5-samps / Age Group, Lineage, Cell class and subclass

NOG LMCD1 ENC1 BCL11A TGFBI

1.12e-0414814255729826e8d45bf995e2efa6707c49e264d12d112
ToppCellDividing_Macrophages-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

ZNF789 DLGAP5 BLM ZNF66 POLQ

1.27e-041521425e39cfc346b35235546b303e7d73e4d9d7120a5fb
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

LMCD1 ME3 DNLZ LYPD5 ZNF616

1.35e-0415414251f8d127b657976656e4ec292f26d619943533b86
ToppCell343B-Myeloid-Dendritic-pDC|343B / Donor, Lineage, Cell class and subclass (all cells)

GCNA SEMA7A BCL11A HNRNPU TGFBI

1.44e-041561425547e2debfc09c07c049a880dded5fda7dd53e156
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TECTA HMCN1 MME DNAH9 HYDIN

1.62e-041601425c381ec6be8cf887861cc18f831a20db42f953fe1
ComputationalNeighborhood of RRM1

DLGAP5 RRM1 HNRNPU PARP1 PRKDC VDAC2

5.93e-05102726MORF_RRM1
Diseaseresponse to bronchodilator, response to corticosteroid

ZNF432 ZNF616 ZNF614

9.51e-0751363GO_0031960, GO_0097366
DiseaseWerner syndrome (implicated_via_orthology)

BLM EXD2 DNA2

9.51e-0751363DOID:5688 (implicated_via_orthology)
Diseasebehavioural disinhibition measurement

ZNF519 NDUFS6 SEMA6D UNC13C SEL1L2 DNAH9

1.33e-06751366EFO_0006946
Diseaserelapsing-remitting multiple sclerosis (is_marker_for)

NOG GRN CD36

4.18e-05151363DOID:2378 (is_marker_for)
Diseasehepcidin:transferrin saturation ratio

EML6 ZNF551 NELL1

4.18e-05151363EFO_0007902
Diseasemyofibrillar myopathy 5 (implicated_via_orthology)

FLNB FLNC

6.31e-0531362DOID:0080096 (implicated_via_orthology)
Diseasedistal muscular dystrophy 4 (implicated_via_orthology)

FLNB FLNC

6.31e-0531362DOID:0111190 (implicated_via_orthology)
DiseaseBloom syndrome (implicated_via_orthology)

BLM DNA2

6.31e-0531362DOID:2717 (implicated_via_orthology)
Diseasediet measurement

ZNF585A MIER3 BCL11A MLLT10 ME1 CIT JMJD1C ZNF585B NELL1 PARP1 SEMA6D ZNF432 UNC13C PRKDC MBD5

1.04e-04104913615EFO_0008111
Diseaseperiostin measurement

STAB2 TRPC4

1.26e-0441362EFO_0020628
DiseaseProstatic Neoplasms

DCAF6 STAB2 PARP1 SETD2 CSRP1 RLIM PRKDC MME CDC27 ZMYM3 ZNF292

1.39e-0461613611C0033578
DiseaseMalignant neoplasm of prostate

DCAF6 STAB2 PARP1 SETD2 CSRP1 RLIM PRKDC MME CDC27 ZMYM3 ZNF292

1.39e-0461613611C0376358
Diseasegrowth/differentiation factor 5 measurement

TGFBI TNFAIP1

3.13e-0461362EFO_0020429
DiseaseFrontotemporal dementia

GRN C9orf72

4.36e-0471362C0338451
DiseaseSemantic Dementia

GRN C9orf72

4.36e-0471362C0338462
DiseaseFrontotemporal Lobar Degeneration

GRN C9orf72

4.36e-0471362C0751072
Diseasesphingomyelin 24:0 measurement

PDGFRL F9

4.36e-0471362EFO_0010397
Diseaseascending aortic diameter

FLNB JMJD1C HMCN1 MBD5 HYDIN

4.90e-041401365EFO_0021787
DiseasePrimary Progressive Nonfluent Aphasia

GRN C9orf72

5.80e-0481362C0751706
DiseaseBehavioral variant of frontotemporal dementia

GRN C9orf72

7.43e-0491362C4011788
DiseaseNodular glomerulosclerosis

TGFBI TNFAIP1 VDAC2

8.98e-04411363C0017667
DiseaseDiabetic Nephropathy

TGFBI TNFAIP1 VDAC2

1.10e-03441363C0011881
Diseasegastrin-releasing peptide measurement

JMJD1C HABP2

1.13e-03111362EFO_0022000
DiseaseAdenoid Cystic Carcinoma

BCL11A JMJD1C SETD2 PRKDC

1.20e-031001364C0010606
DiseaseMitral valve prolapse, response to surgery

LMCD1 SMG6

1.35e-03121362EFO_0009951, HP_0001634
Diseaseurgency urinary incontinence

CIT ADAMTS16

1.35e-03121362EFO_0006865
Diseasephosphatidylcholine 34:4 measurement

F9 MBD5

1.35e-03121362EFO_0010378
DiseaseMalignant neoplasm of breast

FLNB TRPC4 BCL11A TECTA ZNF546 PARP1 SETD2 LLGL1 ZNF432 MME CDC27 FST DNAH9

1.42e-03107413613C0006142
Diseasegranulocyte percentage of myeloid white cells

FLNB JMJD1C LHX2 SETD2 PRKDC ZNF292

1.56e-032681366EFO_0007997
Diseasekynurenic acid measurement

THSD7A SEMA6D

1.59e-03131362EFO_0010506
Diseaseneutrophil count

FLNB DIPK1A PIK3R3 EML6 CIT JMJD1C LHX2 SETD2 CD36 UNC13C PRKDC RAB37 HYDIN ZNF292 SMG6

1.81e-03138213615EFO_0004833
DiseaseProteinuria

UNC13C SMG6

2.13e-03151362HP_0000093
Diseaseautism spectrum disorder (is_implicated_in)

BCL11A MBD5

2.43e-03161362DOID:0060041 (is_implicated_in)
Diseaseeosinophil percentage of leukocytes

MYNN CLSTN1 JMJD1C SETD2 HABP2 PRKDC MBD5 FKBP5 VDAC2 ZNF292

2.46e-0374613610EFO_0007991
Diseasebreast carcinoma

ANO9 ZNF577 MIER3 ENC1 MLLT10 JMJD1C ADCY9 LYPD5 ADAMTS16 HABP2 FST SMG6

2.72e-03101913612EFO_0000305
DiseaseAmyotrophic lateral sclerosis

SPG11 C9orf72

2.74e-03171362cv:C0002736
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

SETD2 ZNF292

2.74e-03171362DOID:0060307 (is_implicated_in)
Diseaselobe attachment

KIF21B NELL1 HMCN1 PRKDC NALF2

2.77e-032071365EFO_0007667
Diseaseplatelet-derived growth factor BB measurement

ME1 JMJD1C CD36

2.84e-03611363EFO_0008264
Diseaseserum hepcidin measurement

EML6 NELL1

3.07e-03181362EFO_0004504
Diseaseneutrophil count, eosinophil count

PIK3R3 EML6 JMJD1C RAB37 ZNF292

3.13e-032131365EFO_0004833, EFO_0004842
Diseaseplatelet measurement

DLGAP5 EML6 JMJD1C PARP1 CD36 SMG6

3.48e-033151366EFO_0005036
Diseaseeosinophil count

ZNF585A ZNF577 DIPK1A ZNF429 MYNN CLSTN1 PPM1A ZNF585B SETD2 HABP2 PRKDC MBD5 FKBP5 VDAC2 ZNF292

3.65e-03148813615EFO_0004842
Diseasephospholipids:total lipids ratio, intermediate density lipoprotein measurement

SPG11 JMJD1C LLGL1

3.70e-03671363EFO_0008595, EFO_0020946
Diseasemitochondrial heteroplasmy measurement

CIT UNC13C FST

4.02e-03691363EFO_0600008

Protein segments in the cluster

PeptideGeneStartEntry
VEYKKSKADCSRCVS

USP26

201

Q9BXU7
SKADCSRCVSYNREK

USP26

206

Q9BXU7
RKICGKSTVISYECC

TGFBI

71

Q15582
CYVEKTSDKVIAADC

SMG6

1111

Q86US8
AEVCCTSIVYATEKK

TNFAIP1

221

Q13829
EAGCKYKEEQLTTGC

BTBD16

216

Q32M84
YTCNVKARSCEKEVV

GRN

486

P28799
AKFGIRCDSCEKYIT

ABLIM2

206

Q6H8Q1
TVTAYDCGKKRATED

CLSTN1

236

O94985
NKSCRVTSLCYSEDG

DCAF6

251

Q58WW2
CLKEGNSTVDCLKGY

ANO9

636

A1A5B4
ASSYQDKLRVICCKG

CIT

1886

O14578
CSKYRSCTINEDTGL

ADAMTS16

411

Q8TE57
IRDYVESQKKRSSCC

RAB37

206

Q96AX2
VEYAKSGRASCKKCS

PARP1

11

P09874
YSCIRKEDISGIASC

LLGL1

901

Q15334
DKNSREGCVYVKCLS

LEMD3

826

Q9Y2U8
REYTKAVECCDKALG

FKBP5

331

Q13451
SKAECSAEQCYKITK

ME1

411

P48163
VVCLDCYKAKERKSS

JMJD1C

1866

Q15652
KEGRRSDTCEYCGKV

BCL11A

736

Q9H165
TTLADKDGEIYCKGC

CSRP1

156

P21291
KENLCVVCGKRDSYI

EXD2

416

Q9NVH0
ISCIDNKDGTCTVTY

FLNB

1866

O75369
YLCQGSSVEVKEDKC

CUL7

826

Q14999
NKVVCSCTEGYRLAE

F9

151

P00740
EQIYSTCVSKLIEGC

KIF21B

61

O75037
INLDKETKTGTCGYC

NDUFS6

101

O75380
SCKDNKDGSCTVEYI

FLNC

1396

Q14315
YSLKGIKTCNCETED

HNRNPU

381

Q00839
TYDDGICKSSDCIKS

MME

51

P08473
CELCGNSYTDIKNLK

MYNN

501

Q9NPC7
LTCFSKDGSIYCKED

LHX2

91

P50458
VCADRVSTYDCGEKI

MOCOS

676

Q96EN8
EYSIRSCTKGCKAVY

NALF2

276

O75949
YKTELSKEECCSTGR

FST

46

P19883
IKEAIERYCCNGKAS

MIER3

261

Q7Z3K6
VETRSKDGVCVCVYT

NPEPPSL1

256

A6NEC2
DKKTITYAGCLVQCF

OR5M3

86

Q8NGP4
ALYTARVDGSKCKCS

CXCL14

26

O95715
NTKATCECKSGYISV

NELL1

411

Q92832
SKEVEYVCELCKGAA

LMCD1

236

Q9NZU5
RYTCEATNVAGKTEK

HMCN1

2171

Q96RW7
QSCCRSTEDLRYGSK

PCDHAC1

716

Q9H158
LIRESSKKGCYACSV

PIK3R3

381

Q92569
DGHCALESKYVKTVC

HABP2

421

Q14520
ECTKTCGEGSRYRKV

ADAMTS9

1566

Q9P2N4
TEVGKESLCKNILCY

HYDIN

4596

Q4G0P3
CCKTKDYKTRDVTDD

BLM

1066

P54132
TTLTEKEGEIYCKGC

CSRP2

156

Q16527
LVYTCKVCGTRSSKR

DNLZ

71

Q5SXM8
NCTSYGVLDISKCKE

CD36

321

P16671
KICYITRKSASCQAD

POLQ

236

O75417
LSCVTYAGDKEERAC

CHD1L

121

Q86WJ1
DCEYKRGIKETTCTD

DLGAP5

491

Q15398
EETKCEKISTLGDCY

ADCY9

431

O60503
DYSVVRGCTTDKCNA

LYPD5

96

Q6UWN5
SKAECTAEKCYRVTE

ME3

446

Q16798
KTYLLTDGTCKCGLE

MBD5

51

Q9P267
YTKSLDTSRFICAKC

GCNA

656

Q96QF7
KEFSACAIGCKVYIT

ENC1

331

O14682
LCLACAKEDITYSGA

EML6

201

Q6ZMW3
TVRCCLLEGYDTKNT

FAM102A

116

Q5T9C2
CSLKYLLENTECKAG

DNAH9

901

Q9NYC9
KSGRCRTTCKESEVY

DEFB121

26

Q5J5C9
IIEEEKTCKYCSQIG

DNA2

386

P51530
QYSTYTELCRGKDCK

DIPK1A

46

Q5T7M9
CVTETLYFGKCLSTK

DIPK1A

81

Q5T7M9
FKILTYSCCSQKRSG

SLC15A4

261

Q8N697
CKTDRLAKGSECYQK

CDC27

126

P30260
SSVSTLKKICRECKY

IPO13

546

O94829
TTCKNDGVCTVRDGK

MEP1B

611

Q16820
LREVTKDQSGKYCCQ

CD22

296

P20273
KCSRLCEAESSFKYE

C9orf72

261

Q96LT7
KLSCADTTRYERGVC

OR2AJ1

186

Q8NGZ0
ICKGYLIDATTITEC

PCGF6

136

Q9BYE7
RYVKVGSCFSKRSCS

NOG

171

Q13253
KCRDLCTSGQGKYSD

MINAR1

486

Q9UPX6
CVRSDGKSVDLKYCE

THSD7A

1251

Q9UPZ6
RSCRTAVELYKGVCE

SEL1L2

461

Q5TEA6
SELGKICSVCISDYV

RNF6

626

Q9Y252
CVSQTEYREKLTIGC

SWT1

851

Q5T5J6
QLCSGYICRKDEAKT

PDGFRL

146

Q15198
CAKCKTQYVRDTVVG

SIRT6

141

Q8N6T7
TCYICDEQGRESKAA

MLLT10

136

P55197
LVYLAGAKCTTCVEE

CLDN6

96

P56747
KDGRCDATILYSCSR

SPG11

121

Q96JI7
AVSLCDSEKYSCKIT

TECTA

2041

O75443
YVCTECRKGFTMKSD

ZNF615

456

Q8N8J6
VCGLYKNDSCTIKEN

VWDE

1041

Q8N2E2
SCRTEYSGVKCEKKI

VWDE

1571

Q8N2E2
CKECGKTFSRASYLV

ZNF30

486

P17039
YKCEECGKAFTRSTT

ZNF595

256

Q8IYB9
YKCEECGKAFTRSTA

ZNF595

536

Q8IYB9
CKECGKAYNLSSTLT

ZNF595

566

Q8IYB9
YECRECGKTFIMSKS

ZNF197

706

O14709
YKCKECGKVFSDRSA

ZNF616

521

Q08AN1
ERSYVCIECGKSLSS

ZNF549

301

Q6P9A3
CIECGKSLSSKYSLV

ZNF549

306

Q6P9A3
YIGESSQRCNKKCII

ZNF519

231

Q8TB69
VVKDCVRACLDSTYK

UNC13C

1541

Q8NB66
KVCNEVVDTCLYKGS

PPM1A

266

P35813
GTIKCSNLCTEIVEY

RRM1

421

P23921
ALKTCSVCITEYTEG

RLIM

566

Q9NVW2
CKECGKAFSYSSDVI

ZNF267

606

Q14586
YECSECEKAFRSKSK

ZNF577

326

Q9BSK1
YECKECGKRLSSNTA

ZNF620

336

Q6ZNG0
TSESTYICKECGKIF

ZNF546

576

Q86UE3
ECGECRKTFSYKSNL

ZNF551

336

Q7Z340
RASKTEEDGVYKCDC

ZNF292

2246

O60281
ECKDCKKVFTYRGSL

ZSCAN5A

441

Q9BUG6
KSSYKRECINLGCDV

VDAC2

126

P45880
EKSSICTECGKAFTY

ZNF585B

351

Q52M93
CSCVVVKDYGKESQA

RPS12

106

P25398
TKGSCLDKRDCENYI

SEMA7A

116

O75326
LKSGCARYCNATVKI

STAB2

711

Q8WWQ8
TRVSCCKTKDSDIYC

SETD2

781

Q9BYW2
EKSSICTECGKAFTY

ZNF585A

351

Q6P3V2
CTSVYTKDRAAKCKI

PRKDC

111

P78527
SKRYSNCMGEITRKC

ZSWIM2

591

Q8NEG5
YKCEECGKAFRKSST

ZNF91

966

Q05481
CEDCGKELKYSSTLT

ZNF90

231

Q03938
SEVGRKSYRCEQCGK

ZNF205

301

O95201
YTCKECGKAFSVRST

ZNF415

376

Q09FC8
YECKECGKSFSLRSS

ZNF790

226

Q6PG37
ERKSYECKECGKTFL

ZNF790

446

Q6PG37
CKQCGKAYRISSSLR

ZNF443

451

Q9Y2A4
EKSYLCSECGKGFTV

ZNF432

426

O94892
LSTIGRCEYEKTCAL

XPO7

446

Q9UIA9
YKCEECAKAFTRSSR

ZNF429

621

Q86V71
ECKECGKVFRYKSSL

ZNF528

466

Q3MIS6
CEECGKDFKYSSTLT

ZNF66

511

Q6ZN08
ESKGSATYCTVCSKK

ZNF622

61

Q969S3
KCEECGSSNLTIYKK

ZNF355P

241

Q9NSJ1
KITHSGEESYKCEEC

ZNF355P

326

Q9NSJ1
GESVCLDRCVSKYLD

TIMM10

46

P62072
GKCEFIYSTQKASCR

TMEFF1

286

Q8IYR6
EKSYICSECGKGFTV

ZNF614

396

Q8N883
RSQTGEKLYKCTECG

ZNF674

216

Q2M3X9
ERYGSCKKSCIASRD

SEMA6D

516

Q8NFY4
SYKCTVCDKAFVRNS

ZNF600

581

Q6ZNG1
CKECGKTFIESAYLI

ZNF329

401

Q86UD4
EGRSSTEKNYKCKEC

ZNF485

121

Q8NCK3
VEKSFCSEGCVLLYK

ZMYM3

651

Q14202
CSEGCVLLYKQDFTK

ZMYM3

656

Q14202
YEETKGLTCKGIRCE

TRPC4

541

Q9UBN4
SRVKCSVCKSVSDTY

USP36

251

Q9P275
TRAKSYECSECGKVI

ZNF789

196

Q5FWF6
VCQECKRGYTSKSDL

ZNF337

686

Q9Y3M9
YECEECGKVIRESSK

ZNF114

361

Q8NC26
YECKQCGKALSSLTS

ZNF439

326

Q8NDP4
KRGKCSDLNEYGTSC

ZNF658B

21

Q4V348
KETIGVGSYSECKRC

RPS6KA1

421

Q15418
VGSYSECKRCVHKAT

RPS6KA1

426

Q15418