Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoBilateral tonic-clonic seizure

CTSF ZNF142 SETD1B GPAA1 ATRX BCKDK NSD1 ADGRV1 CASK EFHC1 KCNN2 PCYT2 MAST3 GABRA1

2.14e-063944314HP:0002069
HumanPhenoGeneralized non-motor (absence) seizure

SETD1B GPAA1 BCKDK NSD1 ADGRV1 CASK EFHC1 MAST3 GABRA1

1.17e-05176439HP:0002121
HumanPhenoNon-motor seizure

SETD1B GPAA1 BCKDK NSD1 ADGRV1 CASK EFHC1 MAST3 GABRA1

2.90e-05197439HP:0033259
DomainKCC1

SLC12A6 SLC12A4

3.25e-0521072IPR000622
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CFH WASHC4 ATRX PEG3 CACHD1 ARMCX4 CMAS AKAP8L HNRNPF CASK ARG2 EFNA1 DROSHA PDE4DIP DLG4 SGSM3 RAB11FIP4

6.05e-0712851101735914814
Pubmed

A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.

LIN7A CASK DLG4

3.63e-0610110314960569
Pubmed

Role of beta-catenin in synaptic vesicle localization and presynaptic assembly.

LIN7A CASK DLG4

3.63e-0610110314622577
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

FRAS1 VPS13C ADGRV1 AKAP9 PDE4DIP DNAH11

9.30e-06152110634299191
Pubmed

Juvenile myoclonic epilepsy with generalised and focal electroencephalographic abnormalities: a case report with a molecular genetic study.

EFHC1 GABRA1

9.91e-062110217972043
Pubmed

Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.

SLC12A6 SLC12A4

9.91e-062110234031912
Pubmed

Coordinated folding and association of the LIN-2, -7 (L27) domain. An obligate heterodimerization involved in assembly of signaling and cell polarity complexes.

LIN7A CASK

9.91e-062110212110687
Pubmed

Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD mice.

SLC12A6 SLC12A4

9.91e-062110217510708
Pubmed

Hair bundle defects and loss of function in the vestibular end organs of mice lacking the receptor-like inositol lipid phosphatase PTPRQ.

ADGRV1 PTPRQ

9.91e-062110222357859
Pubmed

Mutations in the GABRA1 and EFHC1 genes are rare in familial juvenile myoclonic epilepsy.

EFHC1 GABRA1

9.91e-062110216839746
Pubmed

Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma.

DROSHA PDE4DIP

9.91e-062110230030436
Pubmed

A C-terminal PDZ binding domain modulates the function and localization of Kv1.3 channels.

KCNA3 DLG4

9.91e-062110221726550
Pubmed

Genetic disruption of KCC cotransporters in a mouse model of thalassemia intermedia.

SLC12A6 SLC12A4

9.91e-062110231835175
Pubmed

Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.

LIN7A CASK DLG4

2.87e-0519110315024025
Pubmed

Combined genetic disruption of K-Cl cotransporters and Gardos channel KCNN4 rescues erythrocyte dehydration in the SAD mouse model of sickle cell disease.

SLC12A6 SLC12A4

2.97e-053110231352162
Pubmed

C1GALT1 is associated with poor survival and promotes soluble Ephrin A1-mediated cell migration through activation of EPHA2 in gastric cancer.

C1GALT1 EFNA1

2.97e-053110232005975
Pubmed

Erythroid-specific inactivation of Slc12a6/Kcc3 by EpoR promoter-driven Cre expression reduces K-Cl cotransport activity in mouse erythrocytes.

SLC12A6 SLC12A4

2.97e-053110235274823
Pubmed

Cell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval development.

LIN7A CASK

2.97e-053110216688213
Pubmed

Molecular Pathway of Microtubule Organization at the Golgi Apparatus.

AKAP9 PDE4DIP

2.97e-053110227666745
Pubmed

A dominant negative mutant of the KCC1 K-Cl cotransporter: both N- and C-terminal cytoplasmic domains are required for K-Cl cotransport activity.

SLC12A6 SLC12A4

2.97e-053110211551954
Pubmed

Post-synaptic density perturbs insulin-induced Kv1.3 channel modulation via a clustering mechanism involving the SH3 domain.

KCNA3 DLG4

2.97e-053110217854350
Pubmed

Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells.

SLC12A6 SLC12A4

2.97e-053110215262997
Pubmed

K-Cl cotransporter gene expression during human and murine erythroid differentiation.

SLC12A6 SLC12A4

2.97e-053110221733850
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

WASHC4 CAMKK1 ATRX SIN3A CMAS BLK UNC119 EFNA1 AKAP9 PDE4DIP IPMK MAST3

3.22e-059101101236736316
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

BCKDK CMAS AKAP8L HNRNPF LIN7A CASK PNPT1 MSH6 DROSHA VCAN PAN2 NOC4L DDX39B

3.88e-0510821101338697112
Pubmed

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

WASHC4 BCKDK CNTRL AKAP8L AKAP9 ANO6 PDE4DIP

4.74e-05298110732353859
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FRAS1 SETD1B PEG3 NEDD4 AKAP9 ACOT11 PDE4DIP RAB11FIP4

4.76e-05407110812693553
Pubmed

Three types of cilia including a novel 9+4 axoneme on the notochordal plate of the rabbit embryo.

RFX3 DNAH11

5.92e-054110217061268
Pubmed

PNPT1, MYO15A, PTPRQ, and SLC12A2-associated genetic and phenotypic heterogeneity among hearing impaired assortative mating families in Southern India.

PNPT1 PTPRQ

5.92e-054110234374074
Pubmed

Postsynaptic targeting of alternative postsynaptic density-95 isoforms by distinct mechanisms.

CASK DLG4

5.92e-054110212151521
Pubmed

Influence of K-Cl cotransporter activity on activation of volume-sensitive Cl- channels in human osteoblasts.

SLC12A6 SLC12A4

5.92e-054110212637262
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

ATRX ADAMTS12 DMC1 FAT1 MGP PDE4DIP ARMH3 MAST3 DNAH11

6.72e-05552110910737800
Pubmed

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.

RGPD2 ESRRB SIN3A HNRNPF MSH6

7.22e-05135110531077711
Pubmed

Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.

CASK DLG4 UNC13C

7.59e-0526110317124501
Pubmed

RGSZ1 interacts with protein kinase C interacting protein PKCI-1 and modulates mu opioid receptor signaling.

RGS20 RGS17

9.85e-055110217126529
Pubmed

Synaptic multiprotein complexes associated with 5-HT(2C) receptors: a proteomic approach.

CASK DLG4

9.85e-055110212006486
Pubmed

Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex.

LIN7A DLG4

9.85e-055110210341223
Pubmed

Postnatal expression profiles of atypical cadherin FAT1 suggest its role in autism.

FAT1 DLG4

9.85e-055110234100899
Pubmed

Variants in the GH-IGF axis confer susceptibility to lung cancer.

CAMKK1 AKAP9

9.85e-055110216741161
Pubmed

Contrasting localizations of MALS/LIN-7 PDZ proteins in brain and molecular compensation in knockout mice.

LIN7A CASK

9.85e-055110211104771
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

RGPD2 ESRRB SIN3A MSH6 ZFR

1.05e-04146110523892456
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

HK2 SETD1B NSD1 DGKH NEDD4 BLK ADAMTS12 KCNA3 USP4 DNAH11

1.11e-047301101034857952
Pubmed

Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex.

LIN7A CASK DLG4

1.17e-0430110316186258
Pubmed

The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins.

LIN7A DLG4

1.47e-04611029482110
Pubmed

Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology.

CASK DLG4

1.47e-046110221555464
Pubmed

A unified assembly mode revealed by the structures of tetrameric L27 domain complexes formed by mLin-2/mLin-7 and Patj/Pals1 scaffold proteins.

LIN7A CASK

1.47e-046110215863617
Pubmed

Molecular cloning and characterization of Pals, proteins associated with mLin-7.

LIN7A CASK

1.47e-046110210753959
Pubmed

Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain.

CASK DLG4

1.47e-046110211679592
Pubmed

Differential K+ channel clustering activity of PSD-95 and SAP97, two related membrane-associated putative guanylate kinases.

KCNA3 DLG4

1.47e-04611028938729
Pubmed

Promotion of G alpha i3 subunit down-regulation by GIPN, a putative E3 ubiquitin ligase that interacts with RGS-GAIP.

RGS20 RGS17

1.47e-046110212826607
Pubmed

Toward the genetics of mammalian reproduction: induction and mapping of gametogenesis mutants in mice.

DMC1 AKAP9

1.47e-046110212855593
Pubmed

Mrj encodes a DnaJ-related co-chaperone that is essential for murine placental development.

ESRRB DNAJB6

1.47e-046110210021343
Pubmed

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.

VPS13C BCKDK MCCC1

1.57e-0433110325064009
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

CTNNAL1 ATRX CNTRL PEG3 NSD1 GCNT2 HNRNPF MFSD14A VCAN PAN2 IPMK NCKAP1L

1.68e-0410841101211544199
Pubmed

Identification of transcripts with enriched expression in the developing and adult pancreas.

AMBP CFH CTSF SLC36A1 CPXM2 PEG3 ENPP4 NEDD4 AKAP9

1.69e-04624110918554416
Pubmed

RFX2 is essential in the ciliated organ of asymmetry and an RFX2 transgene identifies a population of ciliated cells sufficient for fluid flow.

RFX3 DNAH11

2.06e-047110222233545
Pubmed

A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.

LIN7A CASK

2.06e-04711029753324
Pubmed

Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases.

KCNA3 DLG4

2.06e-04711027477295
Pubmed

Monitoring α-synuclein ubiquitination dynamics reveals key endosomal effectors mediating its trafficking and degradation.

VPS13C NEDD4

2.06e-047110237315142
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

RGPD2 DOCK11 NSD1 ARMCX4 CASK NEDD4 KCNA3 AKAP9 PDE4DIP DLG4 ZFR

2.44e-049631101128671696
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

ATRX ESRRB AKAP8L HNRNPF MSH6

2.56e-04177110526206133
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

RGPD2 HK2 BCKDK MCCC1 NCLN CMAS AKAP8L LIN7A PDE4DIP DLG4 DDX39B GABRA1

2.65e-0411391101236417873
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

HK2 VPS13C BCKDK DGKH ARMCX4 NCLN CMAS CASK ARG2 PNPT1 AKAP9 NOC4L ZFR DDX39B

2.71e-0414961101432877691
Pubmed

AnkG hemizygous mice present cognitive impairment and elevated anxiety/depressive-like traits associated with decreased expression of GABA receptors and postsynaptic density protein.

DLG4 GABRA1

2.74e-048110228821923
Pubmed

Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition.

SLC12A6 SLC12A4

2.74e-048110211395011
Pubmed

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters.

SLC12A6 SLC12A4

2.74e-048110224393035
Pubmed

The quest for juvenile myoclonic epilepsy genes.

EFHC1 GABRA1

2.74e-048110223756480
Pubmed

Identification of potential nuclear reprogramming and differentiation factors by a novel selection method for cloning chromatin-binding proteins.

ATRX NSD1

2.74e-048110215522233
Pubmed

Imbalance of excitatory/inhibitory synaptic protein expression in iPSC-derived neurons from FOXG1(+/-) patients and in foxg1(+/-) mice.

DLG4 GABRA1

2.74e-048110226443267
Pubmed

Similar effects of all WNK3 variants on SLC12 cotransporters.

SLC12A6 SLC12A4

2.74e-048110221613606
Pubmed

Identification of multiple binding partners for the amino-terminal domain of synapse-associated protein 97.

LIN7A CASK

2.74e-048110212351654
Pubmed

N-terminal PDZ-binding domain in Kv1 potassium channels.

KCNA3 DLG4

2.74e-048110212435606
Pubmed

Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1).

SLC12A6 SLC12A4

2.74e-048110212386165
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

FRAS1 CNTRL RFX3 DNAH11

2.94e-04100110425807483
Pubmed

International Lung Cancer Consortium: coordinated association study of 10 potential lung cancer susceptibility variants.

CAMKK1 AKAP9

3.52e-049110220106900
Pubmed

Substrate specificity analysis and novel substrates of the protein lysine methyltransferase NSD1.

ATRX NSD1

3.52e-049110224412544
Pubmed

Cation-chloride cotransporters and neuronal function.

SLC12A6 SLC12A4

3.52e-049110219323993
Pubmed

The nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activity.

CASK DLG4

3.52e-049110217938206
Pubmed

EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.

FRAS1 HNRNPF ZFR

3.71e-0444110327505670
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

WASHC4 DNAJB6 SIN3A CMAS HNRNPF MSH6 PCYT2 ZFR DDX39B

4.09e-04704110929955894
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

BCKDK KCNA3 PDE4DIP DLG4 GABRA1

4.19e-04197110536604605
Pubmed

Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype.

FAT1 DSG4

4.39e-0410110212724416
Pubmed

Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK.

LIN7A CASK

4.39e-0410110218054859
Pubmed

Foxj1 regulates floor plate cilia architecture and modifies the response of cells to sonic hedgehog signalling.

RFX3 DNAH11

4.39e-0410110221098568
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

VPS13C DNAJB6 ADGRV1 MCCC1 CASK VCAN DLG4

4.49e-04430110732581705
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

HK2 ESRRB CMAS NEDD4 MSH6

4.80e-04203110522083510
Pubmed

A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.

PSG1 CNTRL DGKH EFHC1 DNAH6

5.02e-04205110512040188
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

SETD1B ATRX DOCK11 AKAP8L HNRNPF MSH6 DDX39B

5.14e-04440110734244565
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

DNAJB6 HNRNPF MSH6 FAT1

5.87e-04120110427320910
Pubmed

Functional proteomics mapping of a human signaling pathway.

WASHC4 CPXM2 ATRX CASK NEDD4 SLC12A4 DROSHA PDE4DIP

5.96e-04591110815231748
Pubmed

Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.

SLC12A6 SLC12A4

6.41e-0412110227782176
Pubmed

Spatial gene expression in the T-stage mouse metanephros.

ARG2 VCAN

6.41e-0412110216545622
Pubmed

Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport.

LIN7A CASK

6.41e-0412110210846156
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

WASHC4 BCKDK CNTRL NCLN AKAP8L AKAP9 ANO6 PDE4DIP ZFR

6.69e-04754110933060197
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

BCKDK SIN3A CMAS AKAP8L HNRNPF MSH6 DROSHA NOC4L ZFR

7.01e-04759110935915203
Pubmed

Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1.

CTNNAL1 ATRX

7.56e-0413110214690447
Pubmed

A novel scaffold protein, TANC, possibly a rat homolog of Drosophila rolling pebbles (rols), forms a multiprotein complex with various postsynaptic density proteins.

CASK DLG4

7.56e-0413110215673434
Pubmed

The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning.

RFX3 DNAH11

7.56e-0413110217884984
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FRAS1 B4GALNT4 SETD1B NSD1 NCLN TRIM7 UNC119 FAT1 SLC12A4 PCYT2 IQCE

7.69e-0411051101135748872
Pubmed

Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.

MCCC1 HNRNPF NOC4L ZFR

7.70e-04129110428973437
InteractionOR10H1 interactions

SLC12A6 AKAP9 SLC12A4 ANO6 PDE4DIP

6.66e-06491095int:OR10H1
InteractionSLC39A7 interactions

CFH ESRRB CNTRL RGS20 KIF14 RGS17 KCTD18 GABRA1

8.08e-061871098int:SLC39A7
InteractionIFNE interactions

FRAS1 ADGRV1 FAT1 HS3ST1

1.29e-05271094int:IFNE
GeneFamilyBone morphogenetic proteins|Astacins

MEP1B TLL2

2.26e-046712894
GeneFamilyDyneins, axonemal

DNAH6 DNAH11

1.99e-0317712536
GeneFamilyPDZ domain containing

LIN7A CASK DLG4 MAST3

3.01e-031527141220
GeneFamilyRegulators of G-protein signaling

RGS20 RGS17

3.04e-0321712720
GeneFamilyPWWP domain containing

NSD1 MSH6

3.34e-03227121147
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 DGKH GCNT2 LIN7A MEP1B UNC119 IPMK

1.61e-071621107bc63a96ad3ba0b3433e3679d7a005f47709ff384
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC36A1 HK2 DGKH GCNT2 MEP1B UNC119 IPMK

2.06e-07168110703896466698a79f7f1ad862cb7e05585260e2a5a
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

CFH FRAS1 CPXM2 DGKH CACHD1 PTPRQ UNC13C

2.32e-0717111073965ced4be6db14265a90673502fceee425837ca
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH ATRX VPS13C PEG3 NSD1 NEDD4 ZFR

2.82e-071761107749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH HK2 DOCK11 TSPAN2 FAT1 TLL2 VCAN

3.41e-0718111075f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH HK2 DOCK11 TSPAN2 FAT1 TLL2 VCAN

3.41e-071811107c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

CFH FRAS1 ADGRV1 FAT1 MGP RGS17 HS3ST1

4.25e-071871107ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPXM2 ESRRB CACHD1 GCNT2 ACOT11 UNC13C INPP5J

4.40e-071881107eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 ATRX VPS13C PEG3 NEDD4 ADAMTS12 VCAN

4.90e-0719111077d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CTNNAL1 CPXM2 PEG3 CACHD1 GCNT2 UNC13C INPP5J

5.63e-071951107a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH HK2 ATRX VPS13C LIN7A NEDD4 AKAP9

5.63e-0719511075c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CNTRL RFX3 C20orf96 EFHC1 CFAP70 DNAH6 DNAH11

6.24e-071981107ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCelldroplet-Heart-nan-18m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH MON1A ADGRV1 MSH6 MGP ARMH3

3.59e-0616611069adceb746e67e955fd8b3e0984f4eed44b64a270
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ENOSF1 RFX3 EFHC1 CFAP70 DNAH6 DNAH11

3.98e-061691106fba841664939c771881ba97f14ef1df6635c04ff
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DGKH RFX3 EFHC1 CFAP70 DNAH6 DNAH11

3.98e-06169110614aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPXM2 PEG3 CACHD1 ACOT11 UNC13C INPP5J

6.29e-0618311062f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 CPXM2 ESRRB CACHD1 ACOT11 UNC13C

6.29e-0618311062e831a4d99c6f983793df71c0994124c943c6da9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ADGRV1 FAT1 PTPRQ UNC13C DNAH11

6.49e-0618411062cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ADGRV1 FAT1 PTPRQ UNC13C DNAH11

6.49e-061841106ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ADGRV1 FAT1 PTPRQ UNC13C DNAH11

6.49e-0618411062b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FRAS1 ADGRV1 GCNT2 LIN7A EFNA1 PTPRQ

7.12e-0618711064ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPXM2 ESRRB CACHD1 GCNT2 ACOT11 INPP5J

7.34e-061881106bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

RFX3 C20orf96 EFHC1 CFAP70 DNAH6 DNAH11

7.80e-0619011069ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

RFX3 C20orf96 EFHC1 CFAP70 DNAH6 DNAH11

7.80e-061901106833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCelldroplet-Heart-nan-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH PEG3 NEDD4 MGP VCAN PDE4DIP

7.80e-06190110696a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

RFX3 C20orf96 EFHC1 CFAP70 DNAH6 DNAH11

8.28e-061921106be592e661367affced9ebe80849b466e6adb3a34
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ADGRV1 AKAP9 ACOT11 PDE4DIP CFAP70

8.28e-061921106ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell11.5-Airway-Mesenchymal-Cartilage|Airway / Age, Tissue, Lineage and Cell class

CFH CPXM2 PEG3 MGP PDE4DIP RAB11FIP4

8.53e-061931106d4779d92a4dd4b8b656383e6f4fce76d3bd70931
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RFX3 C20orf96 EFHC1 CFAP70 DNAH6 DNAH11

8.53e-061931106e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CACHD1 ADGRV1 EFHC1 CFAP70 DNAH6 DNAH11

8.53e-061931106ea345d34440b25f65358a53dc72831998d1c3620
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

RFX3 C20orf96 EFHC1 CFAP70 DNAH6 DNAH11

8.53e-0619311060b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

RFX3 C20orf96 EFHC1 CFAP70 DNAH6 DNAH11

8.78e-061941106b4ce60c06568123008b1081d644733cb91c28f51
ToppCellRA|World / Chamber and Cluster_Paper

CFH FRAS1 FAT1 MGP VCAN PTPRQ

8.78e-06194110608f0afbb68a63150fbe107a5337299081c3f69e4
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

RFX3 C20orf96 EFHC1 CFAP70 DNAH6 DNAH11

8.78e-0619411067a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RFX3 EFHC1 CFAP70 DNAH6 IQCE DNAH11

9.04e-06195110679dc031258579ea328181dda33710dd897f1064a
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX VPS13C PEG3 NSD1 AKAP9 ZFR

9.04e-0619511063e519cffa6144a62b06124642a14c9ff39b76554
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RFX3 C20orf96 EFHC1 CFAP70 DNAH6 DNAH11

9.04e-0619511063486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RFX3 C20orf96 EFHC1 CFAP70 DNAH6 DNAH11

9.04e-061951106e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

RFX3 C20orf96 EFHC1 CFAP70 DNAH6 DNAH11

9.31e-061961106de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RFX3 C20orf96 EFHC1 CFAP70 DNAH6 DNAH11

9.31e-06196110627b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH TSPAN2 FAT1 RGS20 MGP VCAN

9.31e-061961106023477a499a2c190f363cfdbc9d9c646733a6541
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH TSPAN2 FAT1 RGS20 MGP VCAN

9.31e-0619611063cb74f1a333a82cac2b459f2f1517e2acf22b5fd
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RFX3 C20orf96 EFHC1 CFAP70 DNAH6 DNAH11

9.31e-061961106d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RFX3 EFHC1 AKAP9 CFAP70 DNAH6 DNAH11

9.58e-06197110691637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RFX3 EFHC1 AKAP9 CFAP70 DNAH6 DNAH11

9.58e-06197110622c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RFX3 EFHC1 AKAP9 CFAP70 DNAH6 DNAH11

9.58e-0619711063bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 CPXM2 DGKH CACHD1 FAT1 ACOT11

9.58e-0619711061e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RFX3 EFHC1 AKAP9 CFAP70 DNAH6 DNAH11

9.58e-06197110687db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellTCGA-Skin-Metastatic-Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

ATRX DOCK11 VPS13C MSH6 ZFR NCKAP1L

9.86e-061981106af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRIM7 BLK EFHC1 AKAP9 CFAP70 DNAH6

9.86e-0619811061847ce8c344c8a3e50f3cbbf758a38aba69f85b0
ToppCellTCGA-Skin-Metastatic|TCGA-Skin / Sample_Type by Project: Shred V9

ATRX DOCK11 VPS13C MSH6 ZFR NCKAP1L

9.86e-061981106ad39cce004867f083f8da1954e0cf5a263815184
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

ATRX DOCK11 VPS13C MSH6 ZFR NCKAP1L

9.86e-06198110662cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCell(5)_Dendritic_cell-(51)_cDC1|(5)_Dendritic_cell / shred on Cell_type and subtype

TSPAN2 PDE4DIP RAB15 RAB11FIP4 IQCE

1.37e-051231105d46cfdf8b3e561d8db33903207d5151cdb2a91d4
ToppCellClub_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CFH GCNT2 FAT1 MGP RGS17

3.23e-0514711055a824c89e4d045af465d7333275f8191fb29b041
ToppCellfacs-Heart-LV-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESRRB GCNT2 ARG2 RAB11FIP4 DNAH11

3.67e-0515111055893a51585a65f1902cf85124a5ed9f02b4eb82a
ToppCellfacs-Heart-LV-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESRRB GCNT2 ARG2 RAB11FIP4 DNAH11

3.67e-051511105771224e0d6fccfa4225b3adccd7bc22a89a40793
ToppCellCOVID-19-APC-like-Alveolar_macrophages|COVID-19 / group, cell type (main and fine annotations)

CTSF BCKDK AKAP8L HS3ST1 IPMK

4.29e-051561105735ade77cfa16b9386a0c7ec2bd14bd2e78a51ad
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 CPXM2 ESRRB CACHD1 UNC13C

4.56e-0515811057960337d87afecf2692ab65e5991f052ceddfacc
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_1|COVID-19_Mild / Disease condition and Cell class

WASHC4 ADAMTS12 MFSD14A VCAN ARMH3

5.60e-051651105ef709c5d3231c65d351316e1e31b9c9eba721628
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTSF CPXM2 PEG3 MGP PDE4DIP

5.76e-05166110537794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTSF CPXM2 PEG3 MGP PDE4DIP

5.76e-05166110581c546c6d847e49e662b81e71992ca0f7a99e890
ToppCellBasal_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 B4GALNT4 RGS20 UNC13C HS3ST1

5.76e-051661105aea2ae12e4746149ebc6da063ef694381c098f80
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

TSPAN2 EFHC1 CFAP70 DNAH6 DNAH11

5.93e-05167110526cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ADGRV1 UNC13C DNAH6 DNAH11

6.27e-05169110512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPXM2 ESRRB GCNT2 ACOT11 INPP5J

7.01e-0517311050c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RFX3 EFHC1 CFAP70 DNAH6 DNAH11

7.01e-051731105c3762655caa79ac4879876f470d32578a3c93b01
ToppCell11.5-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

CFH DOCK11 ESRRB MGP KCNN2

7.01e-0517311056989c9cebcd81eccceac7e5a86152676ee959386
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CFH CTNNAL1 CPXM2 TSPAN2 MGP

7.60e-05176110552af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX VPS13C CNTRL NSD1 AKAP9

8.02e-05178110501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellwk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFH RGPD2 CPXM2 PEG3 MGP

8.02e-051781105a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CFH B4GALNT4 TSPAN2 VCAN RGS17

8.23e-051791105e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFH CTNNAL1 CPXM2 TSPAN2 MGP

8.23e-0517911058c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ADGRV1 GCNT2 ACOT11 PDE4DIP

8.45e-0518011059e09b3dfe344b5d50520711513d389865d73a861
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFH FRAS1 ADGRV1 FAT1 RGS17

8.45e-051801105b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell390C-Fibroblasts-Fibroblast-G|390C / Donor, Lineage, Cell class and subclass (all cells)

CFH FRAS1 ADAMTS12 MGP VCAN

8.45e-051801105137fc14859c89e1ecd98bee388bb58c04b835847
ToppCell390C-Fibroblasts-Fibroblast-G-|390C / Donor, Lineage, Cell class and subclass (all cells)

CFH FRAS1 ADAMTS12 MGP VCAN

8.45e-051801105cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|(2)_5-FU / Stress and Cell class

CTSF HK2 PEG3 MGP PDE4DIP

8.67e-05181110556ae86072858c156681507aecd1bc6cb0a3372d2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPXM2 ESRRB CACHD1 GCNT2 UNC13C

8.90e-0518211055f513bbb7125956eb528e3120de3fd776770a7c3
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH MGP VCAN DLG4 RAB15

8.90e-051821105f4b74c2756989812abe4e7055ec8918f69d56025
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF142 PEG3 C1GALT1 HS3ST1 INPP5J

8.90e-051821105818b5155ec81f0059048d6070a108116ecd72e3c
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

HK2 DOCK11 MCCC1 ADAMTS12 ANO6

9.13e-0518311053f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ADGRV1 GCNT2 ACOT11 CFAP70

9.13e-05183110531ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CTNNAL1 CAMKK1 RFX3 MGP MAST3

9.13e-0518311051645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCellwk_20-22-Mesenchymal-Chondrocyte-intermediate_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CFH CPXM2 PEG3 CASK MGP

9.13e-0518311051464b5c4425e8776c4aeb4d2b560481d4bf13931
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM44 B4GALNT4 ARMCX4 KIF14 DNAH11

9.37e-051841105b998803180322a5ea2b567928dea531c26816c3c
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFH CPXM2 NEDD4 MGP PDE4DIP

9.61e-0518511058ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB GCNT2 ACOT11 PDE4DIP UNC13C

9.61e-05185110503f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

RFX3 EFHC1 CFAP70 DNAH6 DNAH11

9.61e-051851105f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH MGP VCAN DLG4 RAB15

9.86e-05186110535c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCellSubstantia_nigra-Neuronal|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

B4GALNT4 PEG3 DLG4 RAB15 RGS17

9.86e-0518611053f889083fcffe516388e9b03a5e23af2010ced33
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH MGP VCAN DLG4 RAB15

9.86e-051861105d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH PEG3 CACHD1 ADAMTS12 VCAN

9.86e-051861105f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 CTNNAL1 DGKH NEDD4 BTN2A2

1.01e-041871105ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH SLC12A6 BLK MGP NCKAP1L

1.01e-041871105b51af2824e65734f333b1325117f4a2e88b17c23
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMKK1 LIN7A UNC13C GABRA1 DNAH11

1.01e-0418711051b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCellfacs-Spleen-nan-3m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH SLC12A6 BLK MGP NCKAP1L

1.01e-0418711053ca3954f45f167e98a230f2847f0582d74fcd32e
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CTNNAL1 DGKH CACHD1 TSPAN2 NEDD4

1.01e-041871105dffa8447c2f3fdacf39a7258c6b4e81a25245041
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-chondrocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CFH CPXM2 PEG3 MGP PDE4DIP

1.04e-0418811055a89587ee6f2b4dc14244bd88bb31efb81c50dbe
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 C1GALT1 CACHD1 TLL2 VCAN

1.04e-041881105b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPXM2 ESRRB ADGRV1 GCNT2 ACOT11

1.06e-041891105f51cdc9a47371cab8ed9ae63a6f14da07ede446c
DrugClioquinol [130-26-7]; Down 200; 13uM; PC3; HT_HG-U133A

CNTRL NEDD4 BTN2A2 VCAN PAN2 SGSM3 MAST3 IQCE

5.06e-0619611084663_DN
DrugFlurbiprofen [5104-49-4]; Up 200; 16.4uM; MCF7; HT_HG-U133A

CTSF SETD1B ATRX GCNT2 TSPAN2 ADAMTS12 UNC119 INPP5J

5.66e-0619911085269_UP
Diseasecalcium/calmodulin-dependent protein kinase kinase 1 measurement

CFH CAMKK1

1.33e-0521082EFO_0020217
Diseaseprotein kinase c gamma type measurement

AMBP CFH

1.33e-0521082EFO_0020680
DiseaseImpulsive Petit Mal Epilepsy

EFHC1 GABRA1

7.93e-0541082C4553298
DiseaseJuvenile Myoclonic Epilepsy of Janz

EFHC1 GABRA1

7.93e-0541082C4551857
DiseaseMyoclonic Epilepsy, Adolescent

EFHC1 GABRA1

7.93e-0541082C4552768
DiseaseJuvenile myoclonic epilepsy

EFHC1 GABRA1

7.93e-0541082cv:C0270853
DiseaseMyoclonic Epilepsy, Juvenile, 1

EFHC1 GABRA1

7.93e-0541082C4553087
Diseaseprobable ATP-dependent RNA helicase DHX58 measurement

CFH DNAJB6

1.32e-0451082EFO_0802901
DiseaseIdiopathic generalized epilepsy

EFHC1 GABRA1

1.97e-0461082cv:C0270850
DiseaseJuvenile Myoclonic Epilepsy

EFHC1 GABRA1

3.66e-0481082C0270853
Diseasezinc fingers and homeoboxes protein 3 measurement

AMBP CFH

4.70e-0491082EFO_0803299
DiseaseAdenoid Cystic Carcinoma

ATRX NSD1 FAT1 VCAN

5.08e-041001084C0010606
Diseasemultiple sclerosis symptom measurement

CPXM2 UNC13C DSG4

6.46e-04461083EFO_0803536
DiseasePR domain zinc finger protein 1 measurement

CFH USP4

7.14e-04111082EFO_0801904
DiseaseUDP-glucuronic acid decarboxylase 1 measurement

CFH ENPP4

7.14e-04111082EFO_0803221
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

SIN3A DLG4 NCKAP1L

7.77e-04491083DOID:0060037 (implicated_via_orthology)
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

PNPT1 PTPRQ

1.01e-03131082C1846647
Diseaseretinol dehydrogenase 16 measurement

AMBP CFH

1.01e-03131082EFO_0802007
Diseasefemoral neck bone geometry

HK2 NSD1

1.17e-03141082EFO_0004511
Diseasesevere acute respiratory syndrome, COVID-19

LIN7A CASK ADAMTS12 C20orf96 PDE4DIP RGS17 UNC13C

1.31e-034471087EFO_0000694, MONDO_0100096
DiseaseIntellectual Disability

ZNF142 BCKDK NSD1 SIN3A PNPT1 PCYT2 DLG4

1.31e-034471087C3714756
DiseaseGlobal developmental delay

ZNF142 GPAA1 PNPT1 PCYT2

1.47e-031331084C0557874
DiseaseMicrocephaly

SIN3A CASK KIF14

1.93e-03671083C0025958
Diseasegait measurement

MON1A KIF14 MAST3 GABRA1

2.28e-031501084EFO_0007680
Diseasetissue factor measurement

AMBP CFH

2.66e-03211082EFO_0010623
Diseaseepilepsy (implicated_via_orthology)

SLC12A6 KCNA3 SLC12A4 UNC13C

3.08e-031631084DOID:1826 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
ITMESYVVHTNYDEY

AMBP

116

P02760
SLVYSTHVDQVREYM

AKAP9

1121

Q99996
REVSYQNDYISSMAD

CNTRL

1121

Q7Z7A1
LTYREGMYIAEEIHN

ARG2

271

P78540
YTQATHDESMTYEDR

VCAN

2646

P13611
HLSTYQSEWMSREEY

ACTL8

346

Q9H568
NYDMPEDSDTYLHRV

DDX39B

361

Q13838
ACSHMSVYAVYARTD

ADGRV1

5886

Q8WXG9
RMVEHYTAYLSDNTR

CACHD1

676

Q5VU97
AHVHTTVNEMSTRYY

DNAH11

3046

Q96DT5
TASMDDIYFEHTISV

ACOT11

91

Q8WXI4
SSYDELYYEIIRMHQ

ARMH3

546

Q5T2E6
VVAHMSDSYQYGEEV

CFH

941

P08603
DNVLYARAYTSEHQM

DMC1

186

Q14565
ARAYTSEHQMELLDY

DMC1

191

Q14565
DRVMDYHFTTAEAST

BCKDK

326

O14874
EYQHMVTNYISEFLR

ARMCX4

2156

Q5H9R4
TKMIEYHGSENVESY

ADAMTS12

256

P58397
YRTFYEDEMASHLDS

AKAP8L

396

Q9ULX6
YYHRRNEMTTTDDLD

CPXM2

301

Q8N436
LVYDISSERSYQHIM

RAB15

86

P59190
YKEQETNSMYHTVFD

RBM44

281

Q6ZP01
RYAQEHDITNFYMLT

NSD1

1986

Q96L73
YEDAQLQIYTLMHRD

RGS17

171

Q9UGC6
MRHVYNSELLDVYCS

RAB11FIP4

261

Q86YS3
AMETYYEEVHRLQTL

IQCE

251

Q6IPM2
DAAHEFTVYRMQQYD

NCLN

41

Q969V3
DHTSYTMEGYINNTL

ANO6

766

Q4KMQ2
TYSTHAVVMYARGTD

FAT1

3861

Q14517
AEEEHGVYVYDLMAT

PAN2

841

Q504Q3
FVYSEAVASHYMRQI

CASK

111

O14936
SNNEYLEYGSHEDAM

CASK

801

O14936
EEVNFLSTYMDHEYS

C20orf96

206

Q9NUD7
VSYHIEMSFFEVYNE

KIF14

486

Q15058
TMKDIYQNRVSYSHD

FRAS1

2376

Q86XX4
REVYQYMHETITVNG

LIN7A

66

O14910
HDMESVDSEYYNSLR

NEDD4

1091

P46934
DETHERYMVSGTNVY

GPAA1

116

O43292
EAQMESYDKHVTYNA

KCNN2

541

Q9H2S1
EYMVRSHYVTETLSE

GCNT2

76

Q8N0V5
YNESEDRHYAMKVLS

CAMKK1

146

Q8N5S9
VLMNAVATEYAAYHQ

LIPT1

226

Q9Y234
GKYIMEEHDSYSDQV

KIAA1109

3056

Q2LD37
QDRMDSSEIYTNTYA

DSG4

706

Q86SJ6
KVDQYLYHMRLSDET

HK2

21

P52789
DAMHTDPDYSAAYVV

ENOSF1

26

Q7L5Y1
HSSQEMSSEYREYAD

PCYT2

161

Q99447
LYEESHGIVANSMYD

ENPP4

81

Q9Y6X5
YYQSFVDVMEFRDHV

NCKAP1L

91

P55160
FYHRETEGEEQSQYM

KCNA3

486

P22001
SDHDMEYTIDVFFRQ

GABRA1

81

P14867
MSTRYHQAASDSYLE

ANKS4B

1

Q8N8V4
EEFYMTIYEDSVATH

DGKH

481

Q86XP1
NHPDSRAIMYEETTY

MSH6

836

P52701
MRVYHVHSDSYETEN

IPMK

181

Q8NFU5
QIMHTRENLYEYGES

PEG3

471

Q9GZU2
YVADITQEHERSMAY

MFSD14A

146

Q96MC6
ITHYTIYAMELDTNR

PTPRQ

641

Q9UMZ3
YSLSDHLANEMETYS

KCTD18

101

Q6PI47
AMFVHARSYEDLTES

MON1A

146

Q86VX9
MVDYYEVLGVQRHAS

DNAJB6

1

O75190
ERHFTMNELTELYTF

ATRX

2196

P46100
VHLSVSSMAERYYNE

DNAH6

2641

Q9C0G6
DKYSHYLAAETEQEM

DOCK11

246

Q5JSL3
LERMEDFTDSAYTSH

CTNNAL1

326

Q9UBT7
DHSVADAAMEQYILY

EFNA1

56

P20827
MDSYNHDIRFDNIYI

DCST1

396

Q5T197
YERTISFVVDASEMH

CFAP70

986

Q5T0N1
HFVVALYDYTAMNDR

BLK

61

P51451
LETEDDYSYQGHMQS

CTSF

351

Q9UBX1
LSYETVTQMEVHYAR

DLG4

521

P78352
VTYNHDGSYSMQIED

MCCC1

566

Q96RQ3
AIRVYMGDSDVYTVH

MAST3

966

O60307
DTDSMYGECRTYIIH

EFHC1

251

Q5JVL4
VSFHYVDSTTMYELE

C1GALT1

306

Q9NS00
YSEHSSYLEMKRFVQ

DCLRE1A

991

Q6PJP8
YAEDYIMDEEHSRLA

ESRRB

301

O95718
DVSFYNMRDRSHIYT

BTN2A2

456

Q8WVV5
VEMHDSDISAYTYER

SLC12A6

976

Q9UHW9
SDSLNVPYDYTSVMH

MEP1B

196

Q16820
VTLCYESHESMESYE

MGP

16

P08493
DYDDTRYHTMQAAVD

NOC4L

176

Q9BVI4
QMRDLYHYITSYVVD

PSG1

71

P11464
ERVLSDYTQVFYNHM

HS3ST1

151

O14792
MYDHRYGDSEFTVQS

HNRNPF

271

P52597
THSENYYSSDPMDQV

DROSHA

416

Q9NRR4
AYYEMRAEHSVDIDV

CMAS

236

Q8NFW8
DEYMFYLVEHRVAQA

RFX3

631

P48380
EQVVFSHMAELYRYD

RGPD2

1346

P0DJD1
DAQLQIYTLMHRDSY

RGS20

351

O76081
DYSMESHQRDHENYV

SGSM3

461

Q96HU1
SSQYEDSLREMFTIH

SIN3A

976

Q96ST3
SYMFRVDHDTIIDAT

SETD1B

1881

Q9UPS6
AMERLYAVFTDYEHD

PNPT1

291

Q8TCS8
VEMHNSDISAYTYER

SLC12A4

911

Q9UP95
VYPNDYTRLTHMETD

B4GALNT4

371

Q76KP1
TQHSYRSHMEYTVSD

INPP5J

706

Q15735
YDEQESEAYEKHVSM

USP4

751

Q13107
AVSFYAVEDMRHLYT

TRIM7

471

Q9C029
EMIRHPYETQSDSFY

UNC119

206

Q13432
TETDEQMQAYDHLSY

UNC13C

896

Q8NB66
ENAIYEMGYTSSHLE

LINC00643

26

Q86TS7
MSTQRLRNEDYHDYS

SLC36A1

1

Q7Z2H8
ETYDFDSIMHYARNT

TLL2

291

Q9Y6L7
MAAVADVTLQVHYYN

VPS13C

2316

Q709C8
DLYEAIDSEGHSYMR

SMIM8

76

Q96KF7
EMQQYFTYHTHIERS

ERVH48-1

56

M5A8F1
SSDDRYVMTKHATIY

ZFR

721

Q96KR1
YENAVDAARLHYMFS

WASHC4

621

Q2M389
MHEDISNFYSDTYAC

ZNF142

241

P52746
AIRHVQTMYEEAYND

TSPAN2

116

O60636
HYGAMRTVTEQYEEV

XIRP1

1761

Q702N8
EEASYMASDRTYQRE

ZNF805

606

Q5CZA5
SDMDIVSEYTHYEEK

PDE4DIP

1621

Q5VU43