Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainEGF_Ca-bd_CS

MEGF8 CD248 CRB2

1.98e-0397483IPR018097
DomainEGF_CA

MEGF8 CD248 CRB2

2.10e-0399483PS01187
DomainEGF-type_Asp/Asn_hydroxyl_site

MEGF8 CD248 CRB2

2.55e-03106483IPR000152
DomainEGF_3

MEGF8 CD248 ADAM11 CRB2

3.08e-03235484PS50026
DomainEGF

MEGF8 CD248 ADAM11 CRB2

3.08e-03235484SM00181
DomainEGF-like_dom

MEGF8 CD248 ADAM11 CRB2

3.79e-03249484IPR000742
DomainEGF_CA

MEGF8 CD248 CRB2

3.80e-03122483SM00179
DomainEGF-like_Ca-bd_dom

MEGF8 CD248 CRB2

3.97e-03124483IPR001881
DomainEGF_1

MEGF8 CD248 ADAM11 CRB2

4.12e-03255484PS00022
DomainEGF-like_CS

MEGF8 CD248 ADAM11 CRB2

4.48e-03261484IPR013032
DomainEGF_2

MEGF8 CD248 ADAM11 CRB2

4.72e-03265484PS01186
DomainGrowth_fac_rcpt_

CCN5 MEGF8 CD248

7.51e-03156483IPR009030
Pubmed

Kidney and retinal defects (Krd), a transgene-induced mutation with a deletion of mouse chromosome 19 that includes the Pax2 locus.

ADRB1 HPS6

8.69e-05104927835879
Pubmed

Molecular map of chromosome 19 including three genes affecting bleeding time: ep, ru, and bm.

ADRB1 HPS6

8.69e-05104928043950
Pubmed

A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells.

TSPO CPOX

1.27e-041249220508144
Pubmed

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.

CD248 PELI3 GLYCTK

4.09e-0410249321926972
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

ARHGAP22 MEGF8 CARD10

6.26e-0411849321078624
Pubmed

Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.

URB1 PIGT TSPO PEX11B

8.06e-0429649434186245
Pubmed

Diversification of molecularly defined myenteric neuron classes revealed by single-cell RNA sequencing.

RPRML NMU

9.39e-043249233288908
Pubmed

[IMAGE: molecular integration of the analysis of the human genome and its expression].

C21orf58 FASTK

1.12e-03354927757816
Pubmed

Defining the membrane proteome of NK cells.

NCAPD3 PIGT GUSB HPS6 PEX11B EXOC7 SLC37A4

1.19e-03116849719946888
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

URB1 FASTK SHROOM2 NXPH3

1.19e-0332949417474147
Pubmed

Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains.

SHROOM2 CRB2

1.25e-033749225742799
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ARHGAP22 COL4A6 MMP28 CRB2 NMU

1.83e-06185495492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGAP22 COL4A6 MMP28 CRB2 NMU

1.93e-061874958e8f1f2a78ac5f13a414fd448af7d7ff1ea86f0f
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD248 S1PR2 IGFL3 PTGER1 CRB2

2.26e-06193495b05361ffe111a38cfa26eb86e4ae62c15ac99b7b
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP28 CARD10 SHROOM2 CRB2

2.88e-0516049433050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCellBac-SEP-Myeloid-tDC|Bac-SEP / Disease, Lineage and Cell Type

MEGF8 ETFBKMT SLC37A4 CRB2

3.25e-051654948728f927502e56f2768b4224e9111939d3d7815a
ToppCellP28|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCN5 ADRB1 RPRML TSPO

3.49e-051684944ee59a6147bbe7e4a03cc2d6fe9d6c10b18a3a06
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 C21orf58 ESPL1 NMU

4.09e-05175494876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1|bone_marrow / Manually curated celltypes from each tissue

C21orf58 TSPO ADAM11 ESPL1

4.66e-05181494ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 C21orf58 ESPL1 NMU

4.76e-05182494336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCN5 C21orf58 CRB2 TMEM89

4.86e-0518349418040d0653286071df959513c63d94b555a5d00a
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCN5 C21orf58 CRB2 TMEM89

4.86e-051834946ca7c2d7c56e0f1b9038ba677b4c1c3dfd63bfce
ToppCellwk_20-22-Mesenchymal-Mesothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ARHGAP22 MMP28 CRB2 NMU

4.97e-05184494804f8a41cd6b1361448872bf352bf0a38a0fac66
ToppCellwk_20-22-Mesenchymal-Mesothelial-Late_mesothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ARHGAP22 MMP28 CRB2 NMU

4.97e-0518449460dd055c2e2e92b838ac649c12e8cccd9c3b1b71
ToppCellwk_15-18-Mesenchymal-Mesothelial-Late_mesothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARHGAP22 MMP28 CRB2 NMU

5.40e-0518849438a53f99f1876359983936403aefca93281d10fd
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ARHGAP22 MMP28 CRB2 NMU

5.40e-051884949655a4c47b644a870017d349b99063e17dbae572
ToppCellwk_15-18-Mesenchymal-Mesothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARHGAP22 MMP28 CRB2 NMU

5.74e-05191494b5374674312ff5803a1d369f5533027532344679
ToppCellwk_08-11-Mesenchymal-Mesothelial-intermediate_mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ARHGAP22 MMP28 CRB2 NMU

5.86e-05192494ac9e5288ecd4b1e142f2e15a1fcd11c8eb9e15cd
ToppCellwk_08-11-Mesenchymal-Mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ARHGAP22 MMP28 CRB2 NMU

6.22e-051954949016a44b521214546a55a822ebdef5b5312206d2
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP28 TSPO CRB2 NMU

6.35e-05196494ee89f6884aea11aefeaabe043db7f80145dcdf7f
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP28 TSPO CRB2 NMU

6.35e-05196494e75c36cb042342d69a593fb1ce62fab033889871
ToppCell10x3'2.3-week_17-19-Hematopoietic-erythroid-early_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

C21orf58 CPOX SLC37A4 NMU

6.60e-051984948d900a17667a41bdfa683a34275fe4c059f6a8ef
ToppCell15-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

NCAPD3 C21orf58 ESPL1 NMU

6.73e-051994945c8b847b794b3e88722f5b841f2539a27251106c
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Proliferative_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

CCN5 TMEM198 GLYCTK PTGER1

6.73e-05199494eb5971660dff356721a004f821d52a5b7a33c951
Drugpyrachlostrobin

CCN5 COL4A6 LIMD1 CD248 GUSB TSPO S1PR2 ADAM11 NXPH3 CRB2

5.96e-068114810ctd:C513428
DiseaseNEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE

COQ8B CRB2

1.05e-0330472C1868672
Diseasetotal cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement

ADRB1 C5orf47

2.78e-0349472EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
DiseasePremature atrial contractions

ADRB1 S1PR2

3.49e-0355472HP_0006699

Protein segments in the cluster

PeptideGeneStartEntry
PARLLEPWAGCNGGA

ADRB1

441

P08588
WPLGKPEGLLARGCG

CARD10

576

Q9BWT7
GPWGLIGLPGLKGAR

COL4A6

501

Q14031
ATPACPGALGPNWGR

CCDC187

881

A0A096LP49
QPEGGVGWSRAGPLC

CD248

216

Q9HCU0
GPAGALRWGGLPQLG

ADAM11

26

O75078
EAVGGLGPGAWACLP

C8orf58

171

Q8NAV2
LGPGAWACLPGQGLR

C8orf58

176

Q8NAV2
PVLNCWGALPLGGKA

ACTR10

156

Q9NZ32
CCLGPSKWGDRPVGG

FASTK

61

Q14296
GPVNGGGRLGPQARW

LIMD1

76

Q9UGP4
WCAGACRGAPILPQG

NMU

31

P48645
GGKWQPGRGPCVLQE

NEIL1

126

Q96FI4
GHVSLCWRPGPGAGC

IL17REL

231

Q6ZVW7
SQPWGGPFRGCLQDL

CRB2

756

Q5IJ48
GLGPPGGWRQALLAG

PTGER1

191

P34995
FLAPLLLTGAGGPWG

MEGF8

2731

Q7Z7M0
TPRGGLPGPWINAAC

EXOC7

306

Q9UPT5
EAGPGLCRNGWAPAP

KCNJ14

26

Q9UNX9
GLAQGLGWPPCGKVL

SLC37A4

111

O43826
WGQGPGAGCRQEKPR

C5orf47

41

Q569G3
LLQGWLGAGPGAPLL

ESPL1

2076

Q14674
AWGRGPVCLLAGGEP

GLYCTK

396

Q8IVS8
LLCGWSPGGKARPAG

C21orf58

31

P58505
ALGPLLWGCALGLQG

GUSB

11

P08236
GSGLWLCQPTPRCGN

IGFL3

31

Q6UXB1
WVCGQGGGLGTQPLP

CCN5

161

O76076
CRAGNAALGLGGPWQ

DGCR6L

191

Q9BY27
LGQTVGWPCGALGPG

COQ8B

16

Q96D53
LLLFPCGQCPWRGAG

ETFBKMT

26

Q8IXQ9
GWRPLQSTELCPGGG

HPS6

111

Q86YV9
GLWRCGPGIVGLCGL

PEX11B

226

O96011
VLGGLPILGWNCLGH

S1PR2

161

O95136
GPCWLVARGGCGGPR

CPOX

11

P36551
LGLLAPPGEAWGILG

NXPH3

66

O95157
PVWGLPQLCRAGGLP

MMP28

401

Q9H239
GLGTWLGCCPGGAPL

RPRML

31

Q8N4K4
GGWGGRPRPGNILLQ

TRPC4AP

26

Q8TEL6
LWLGQEAGLCLDPGP

PELI3

396

Q8N2H9
GSGWQGPRPCVQGDL

SHROOM2

471

Q13796
WCLQAGPGLGLQGDL

URB1

1251

O60287
GPTSPRGGLQCAVGW

ARHGAP22

356

Q7Z5H3
GLGSGLQPWCPLDLR

NCAPD3

6

P42695
AWGGPGCRAQKGIPA

TPRX1

76

Q8N7U7
VLLLLGPGGWCLAEP

PIGT

11

Q969N2
LWCPTNGLGLGGSPA

TSPO

6

B1AH88
GWELKCPGAAGVLGP

THTPA

61

Q9BU02
GQRPFKCPLGGCGWT

ZXDA

296

P98168
GLSCPGYWLGPGASR

TMEM89

51

A2RUT3
VWGPLGLLLGGGLLC

TMEM198

146

Q66K66