Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

5.54e-11261828GO:0005248
GeneOntologyMolecularFunctionATP hydrolysis activity

DNAH3 ABCC4 ABCA3 KIF1A ABCA13 ATAD5 PEX6 PSMC4 TRIP13 ABCG4 ABCB10 ABCA5 DDX54 KIF14 MACF1 ABCC12 ASCC3 ATP12A ATP2B2 ATP5F1B ATP5F1C

6.81e-1044118221GO:0016887
GeneOntologyMolecularFunctionsodium channel activity

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.18e-08521828GO:0005272
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCC4 ABCA3 ABCA13 ABCG4 ABCB10 ABCA5 ABCC12 ATP12A ATP2B2 ATP5F1B

6.04e-0810918210GO:0042626
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

1.12e-07141825GO:0031402
GeneOntologyMolecularFunctionATP-dependent activity

DNAH3 ABCC4 ABCA3 KIF1A ABCA13 ATAD5 PEX6 PSMC4 TRIP13 ABCG4 ABCB10 ABCA5 DDX54 KIF14 MACF1 ABCC12 ASCC3 ATP12A ATP2B2 ATP5F1B ATP5F1C

2.10e-0761418221GO:0140657
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC4 ABCA3 ABCA13 ABCG4 ABCB10 ABCA5 ABCC12

2.90e-07491827GO:0140359
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SLC17A8 ATP12A SLC17A6

4.97e-0717118211GO:0015081
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCC4 ABCA3 ABCA13 NDUFS3 ABCG4 ABCB10 ABCA5 ABCC12 ATP12A ATP2B2 ATP5F1B

7.41e-0717818211GO:0015399
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DNAH3 ABCC4 ABCA3 KIF1A ABCA13 ATAD5 PEX6 PSMC4 TRIP13 ABCG4 ABCB10 ABCA5 DDX54 KIF14 MACF1 ABCC12 ASCC3 ATP12A ATP2B2 TBCC ATP5F1B ATP5F1C

2.40e-0677518222GO:0017111
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

3.35e-06261825GO:0031420
GeneOntologyMolecularFunctiontransporter activity

SLC25A41 SCN11A ABCC4 ABCA3 ABCA13 SLCO2B1 SLC25A33 PEX6 NDUFS3 GRAMD1B ABCG4 CATSPER1 ABCB10 ABCA5 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A SLC17A8 ABCC12 ATP12A ATP2B2 ATP5F1B SLC17A6 ATP5F1C

5.71e-06128918229GO:0005215
GeneOntologyMolecularFunctionpyrophosphatase activity

DNAH3 ABCC4 ABCA3 KIF1A ABCA13 ATAD5 PEX6 PSMC4 TRIP13 ABCG4 ABCB10 ABCA5 DDX54 KIF14 MACF1 ABCC12 ASCC3 ATP12A ATP2B2 TBCC ATP5F1B ATP5F1C

8.50e-0683918222GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

DNAH3 ABCC4 ABCA3 KIF1A ABCA13 ATAD5 PEX6 PSMC4 TRIP13 ABCG4 ABCB10 ABCA5 DDX54 KIF14 MACF1 ABCC12 ASCC3 ATP12A ATP2B2 TBCC ATP5F1B ATP5F1C

8.66e-0684018222GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

DNAH3 ABCC4 ABCA3 KIF1A ABCA13 ATAD5 PEX6 PSMC4 TRIP13 ABCG4 ABCB10 ABCA5 DDX54 KIF14 MACF1 ABCC12 ASCC3 ATP12A ATP2B2 TBCC ATP5F1B ATP5F1C

8.66e-0684018222GO:0016818
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC25A41 SCN11A ABCC4 ABCA3 ABCA13 SLCO2B1 SLC25A33 NDUFS3 ABCG4 CATSPER1 ABCB10 ABCA5 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A SLC17A8 ABCC12 ATP12A ATP2B2 ATP5F1B SLC17A6 ATP5F1C

9.23e-06118018227GO:0022857
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SCN11A NDUFS3 CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A SLC17A8 ATP12A ATP2B2 ATP5F1B SLC17A6 ATP5F1C

6.34e-0562718217GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SCN11A CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A ATP5F1B ATP5F1C

7.63e-0534318212GO:0005261
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SCN11A CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A SLC17A8 ATP5F1B SLC17A6 ATP5F1C

8.45e-0545918214GO:0005216
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SCN11A CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A SLC17A8 ATP12A ATP2B2 SLC17A6

9.70e-0546518214GO:0046873
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCC4 ABCA3 ABCA13 SLCO2B1 NDUFS3 ABCG4 ABCB10 ABCA5 SLC17A8 ABCC12 ATP12A ATP2B2 ATP5F1B SLC17A6

1.27e-0447718214GO:0022804
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SCN11A NDUFS3 CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A SLC17A8 ATP12A ATP2B2 ATP5F1B SLC17A6 ATP5F1C

1.27e-0466418217GO:0008324
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SCN11A ABCC4 NDUFS3 CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A SLC17A8 ATP12A ATP2B2 ATP5F1B SLC17A6 ATP5F1C

2.04e-0475818218GO:0015318
GeneOntologyMolecularFunctionL-glutamate uniporter activity

SLC17A8 SLC17A6

2.46e-0431822GO:0140788
GeneOntologyMolecularFunctionchannel activity

SCN11A CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A SLC17A8 ATP5F1B SLC17A6 ATP5F1C

3.38e-0452518214GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SCN11A CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A SLC17A8 ATP5F1B SLC17A6 ATP5F1C

3.44e-0452618214GO:0022803
GeneOntologyMolecularFunctionmembrane potential driven uniporter activity

SLC17A8 SLC17A6

8.11e-0451822GO:0022810
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SCN11A NDUFS3 CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A SLC17A8 ATP12A ATP2B2 ATP5F1B SLC17A6 ATP5F1C

9.68e-0479318217GO:0015075
GeneOntologyMolecularFunctionlipid transporter activity

ABCC4 ABCA3 ABCA13 SLCO2B1 GRAMD1B ABCG4 ABCA5

2.18e-031961827GO:0005319
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

7.39e-10361818GO:0086010
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN11A SPTBN4 GHSR SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

5.51e-0811218110GO:0019226
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

6.80e-08621818GO:0086002
GeneOntologyBiologicalProcessneuronal action potential

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

7.73e-08631818GO:0019228
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SCN11A HECW2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SLC17A8 ATP12A SLC17A6

3.22e-0720818112GO:0035725
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

9.75e-07871818GO:0086001
GeneOntologyBiologicalProcesssodium ion transport

SCN11A SPTBN4 HECW2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SLC17A8 ATP12A SLC17A6

9.99e-0727518113GO:0006814
GeneOntologyBiologicalProcessmembrane depolarization

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A PHOX2B

1.23e-061211819GO:0051899
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.62e-06931818GO:0086003
GeneOntologyBiologicalProcessbrain development

CCDC14 MKKS CNTN4 KIF1A SAMD4B DVL3 GBX2 KAT2A OGDH SHANK3 CCDC39 NDUFS3 PHOX2A GDF7 SCN2A SCN5A ASPM KIF14 KDM7A ATIC PRKDC PHOX2B ATP2B2

1.97e-0685918123GO:0007420
GeneOntologyBiologicalProcesshead development

CCDC14 MKKS CNTN4 KIF1A SAMD4B DVL3 GBX2 KAT2A OGDH SHANK3 CCDC39 NDUFS3 PHOX2A GDF7 SCN2A SCN5A ASPM KIF14 KDM7A ATIC PRKDC PHOX2B ATP2B2

6.02e-0691918123GO:0060322
GeneOntologyBiologicalProcessmetencephalon development

SAMD4B GBX2 KAT2A OGDH PHOX2A SCN5A KIF14 ATIC ATP2B2

8.52e-061531819GO:0022037
GeneOntologyBiologicalProcesshindbrain development

SAMD4B GBX2 KAT2A OGDH PHOX2A SCN5A KIF14 ATIC PHOX2B ATP2B2

1.58e-0520818110GO:0030902
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.66e-051271818GO:0070252
GeneOntologyBiologicalProcessmidbrain development

CCDC14 DVL3 KAT2A NDUFS3 PHOX2A GDF7 KDM7A

2.36e-05971817GO:0030901
GeneOntologyBiologicalProcesscentral nervous system development

CCDC14 MKKS CNTN4 KIF1A SAMD4B DVL3 GBX2 KAT2A OGDH SHANK3 CCDC39 NDUFS3 SPTBN4 ZIC4 PHOX2A GDF7 SCN2A SCN5A ASPM KIF14 KDM7A ATIC PRKDC PHOX2B ATP2B2

4.93e-05119718125GO:0007417
GeneOntologyBiologicalProcessdetection of mechanical stimulus

MKKS SCN11A SCN1A PKD1 SCN9A ATP2B2

5.12e-05751816GO:0050982
GeneOntologyBiologicalProcessregulation of mitotic cell cycle phase transition

ATAD5 APC NBN TERT TRIP13 HECW2 PKD1 KIF14 SENP2 LSM11 PRKDC PHOX2B CDC25B

5.81e-0540218113GO:1901990
GeneOntologyBiologicalProcessactin filament-based movement

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

6.31e-051531818GO:0030048
GeneOntologyBiologicalProcessneuron projection morphogenesis

CNTN4 SCN11A SEMA3C KIF1A SYT17 DVL3 APC LAMA3 GBX2 NIBAN2 SHANK3 TRAK1 ITPKA SPTBN4 GDF7 HECW2 MACF1 RIMS1 PHOX2B

8.50e-0580218119GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

CNTN4 SCN11A SEMA3C KIF1A SYT17 DVL3 APC LAMA3 GBX2 NIBAN2 SHANK3 TRAK1 ITPKA SPTBN4 GDF7 HECW2 MACF1 RIMS1 PHOX2B

1.12e-0481918119GO:0120039
GeneOntologyBiologicalProcesscardiac muscle contraction

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.16e-041671818GO:0060048
GeneOntologyBiologicalProcesscell projection morphogenesis

CNTN4 SCN11A SEMA3C KIF1A SYT17 DVL3 APC LAMA3 GBX2 NIBAN2 SHANK3 TRAK1 ITPKA SPTBN4 GDF7 HECW2 MACF1 RIMS1 PHOX2B

1.25e-0482618119GO:0048858
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception

MKKS SCN11A SCN1A SCN9A ATP2B2

1.42e-04571815GO:0050974
GeneOntologyBiologicalProcesscerebellum development

SAMD4B GBX2 OGDH SCN5A KIF14 ATIC ATP2B2

2.30e-041391817GO:0021549
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

MKKS SCN11A SPTBN4 SCN1A SCN8A SCN9A SLC17A8 ATP2B2 GRAP

2.63e-042381819GO:0050954
GeneOntologyBiologicalProcessheart contraction

SCN11A SPTBN4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A ATP2B2

3.14e-0429818110GO:0060047
GeneOntologyBiologicalProcesscell morphogenesis

CNTN4 SCN11A SEMA3C KIF1A SYT17 DVL3 APC LAMA3 GBX2 NIBAN2 POF1B SHANK3 TRAK1 ITPKA SPTBN4 HOXA13 GDF7 HECW2 MACF1 RIMS1 PRKDC PHOX2B ATP2B2

3.28e-04119418123GO:0000902
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

CNTN4 SCN11A SEMA3C KIF1A APC LAMA3 GBX2 NIBAN2 SHANK3 TRAK1 ITPKA SPTBN4 GDF7 HECW2 MACF1 PHOX2B ATP2B2

3.29e-0474818117GO:0048667
GeneOntologyBiologicalProcesssomatic recombination of immunoglobulin gene segments

ATAD5 NBN KMT5B CCR6 PRKDC

3.51e-04691815GO:0016447
GeneOntologyBiologicalProcessheart development

EPHB4 MKKS SEMA3C SPEG DVL3 APC KAT2A BCOR CCDC39 HOXA13 SMYD4 GPC3 ADAMTS6 SCN5A PKD1 SENP2 PRKDC

3.78e-0475718117GO:0007507
GeneOntologyBiologicalProcessnerve development

TMEM126A PHOX2A SCN1A SCN2A SCN8A PHOX2B

4.03e-041091816GO:0021675
GeneOntologyBiologicalProcesspositive regulation of sterol transport

ABCA3 ABCA13 ABCG4 ABCA5

4.10e-04401814GO:0032373
GeneOntologyBiologicalProcesspositive regulation of cholesterol transport

ABCA3 ABCA13 ABCG4 ABCA5

4.10e-04401814GO:0032376
GeneOntologyBiologicalProcessaction potential

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

4.11e-042011818GO:0001508
GeneOntologyBiologicalProcessheart process

SCN11A SPTBN4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A ATP2B2

4.18e-0430918110GO:0003015
GeneOntologyBiologicalProcessregulation of cilium beat frequency

MKKS CCDC39 CATSPER1

4.92e-04181813GO:0003356
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

6.43e-13171828GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.04e-10291828GO:0034706
GeneOntologyCellularComponentcation channel complex

SCN11A CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A ATP5F1B ATP5F1C

1.09e-0623518212GO:0034703
GeneOntologyCellularComponentmonoatomic ion channel complex

SCN11A CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A SLC17A8 ATP5F1B SLC17A6 ATP5F1C

6.07e-0637818214GO:0034702
GeneOntologyCellularComponenttransmembrane transporter complex

SCN11A NDUFS3 CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A SLC17A8 ATP12A ATP5F1B SLC17A6 ATP5F1C

1.45e-0552318216GO:1902495
GeneOntologyCellularComponentnode of Ranvier

SPTBN4 SCN1A SCN2A SCN8A

2.42e-05201824GO:0033268
GeneOntologyCellularComponenttransporter complex

SCN11A NDUFS3 CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A PKD1 SCN8A SCN9A SLC17A8 ATP12A ATP5F1B SLC17A6 ATP5F1C

2.67e-0555018216GO:1990351
GeneOntologyCellularComponentaxon initial segment

SPTBN4 SCN1A SCN2A SCN8A

1.11e-04291824GO:0043194
GeneOntologyCellularComponentpericellular basket

SLC17A8 SLC17A6

2.25e-0431822GO:1990030
GeneOntologyCellularComponentglutamatergic synapse

SCN11A VEZT SYT17 DVL3 APC SHANK3 ARHGEF15 ITPKA EFR3A GHSR SCN2A SCN8A SLC17A8 RIMS1 ADGRL2 IL1RAP ATP2B2

8.15e-0481718217GO:0098978
GeneOntologyCellularComponentproton-transporting ATP synthase complex, catalytic core F(1)

ATP5F1B ATP5F1C

1.11e-0361822GO:0045261
MousePhenopostnatal lethality, complete penetrance

KIF1A SPEG DVL3 APC LAMA3 KAT2A CCDC39 CEP55 PHOX2A GPC3 HECW2 SCN1A SCN2A PKD1 SCN8A KIF14 SLC17A6

3.62e-0644514517MP:0011085
MousePhenopostnatal lethality

TET2 KIF1A SPEG PEG3 DVL3 APC LAMA3 RFX6 KAT2A TRIP13 CCDC39 CEP55 ZIC4 PHOX2A GPC3 HECW2 SCN1A SCN2A SCN5A PKD1 SCN8A TPH2 SCN9A KIF14 PRKDC HERC2 PHOX2B SLC17A6

5.55e-06108414528MP:0002082
MousePhenoabnormal locus ceruleus morphology

GBX2 PHOX2A PHOX2B

3.71e-0571453MP:0003661
MousePhenoabnormal cyst

EPHB4 GPR39 APC ZC3HC1 GBX2 CCDC39 TRAK1 CEP55 HOXA13 GPC3 PKD1 PRKDC

5.60e-0529414512MP:0031310
MousePhenoabnormal action potential

SCN11A SCN1A SCN2A SCN5A SCN8A SCN9A SLC17A8 ATP2B2

7.26e-051331458MP:0005402
MousePhenoabnormal breathing pattern

ABCA3 SYT17 DVL3 KAT2A PHOX2A SCN1A SCN2A SCN4A PKD1 SCN8A TPH2 PHOX2B

7.48e-0530314512MP:0001951
MousePhenoincreased kidney epithelial cell primary cilium length

CEP55 PKD1

1.07e-0421452MP:0020382
DomainNa_channel_asu

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.57e-15101788IPR001696
DomainNa_trans_assoc

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.57e-15101788IPR010526
DomainNa_trans_assoc

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.57e-15101788PF06512
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

6.89e-1361786PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

6.89e-1361786IPR024583
DomainAAA

DNAH3 ABCC4 ABCA3 ABCA13 ATAD5 PEX6 PSMC4 TRIP13 ABCG4 ABCB10 ABCA5 ABCC12 ASCC3 ATP5F1B

1.02e-1014417814SM00382
DomainAAA+_ATPase

DNAH3 ABCC4 ABCA3 ABCA13 ATAD5 PEX6 PSMC4 TRIP13 ABCG4 ABCB10 ABCA5 ABCC12 ASCC3 ATP5F1B

1.02e-1014417814IPR003593
DomainChannel_four-helix_dom

SCN11A CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.22e-09571789IPR027359
Domain-

SCN11A CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.22e-095717891.20.120.350
DomainABC_tran

ABCC4 ABCA3 ABCA13 ABCG4 ABCB10 ABCA5 ABCC12

3.36e-07481787PF00005
DomainABC_TRANSPORTER_2

ABCC4 ABCA3 ABCA13 ABCG4 ABCB10 ABCA5 ABCC12

3.36e-07481787PS50893
DomainABC_TRANSPORTER_1

ABCC4 ABCA3 ABCA13 ABCG4 ABCB10 ABCA5 ABCC12

3.89e-07491787PS00211
DomainABC_transporter-like

ABCC4 ABCA3 ABCA13 ABCG4 ABCB10 ABCA5 ABCC12

4.49e-07501787IPR003439
DomainIQ

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A ASPM

1.03e-06811788SM00015
DomainIon_trans_dom

SCN11A CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.46e-061141789IPR005821
DomainIon_trans

SCN11A CATSPER1 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.46e-061141789PF00520
DomainIQ_motif_EF-hand-BS

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A ASPM

2.32e-06901788IPR000048
DomainABC_transporter_CS

ABCC4 ABCA3 ABCG4 ABCB10 ABCA5 ABCC12

2.72e-06421786IPR017871
DomainIQ

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A ASPM

2.97e-06931788PS50096
DomainIQ

SCN1A SCN3A SCN4A SCN8A SCN9A ASPM

5.90e-05711786PF00612
DomainP-loop_NTPase

DNAH3 ABCC4 ABCA3 KIF1A ABCA13 ATAD5 NOA1 PEX6 PSMC4 TRIP13 ABCG4 GTPBP8 ABCB10 ABCA5 DDX54 ASPM KIF14 ABCC12 ASCC3 ATP5F1B

1.75e-0484817820IPR027417
DomainABC_A

ABCA3 ABCA13 ABCA5

1.76e-04121783IPR026082
DomainAAA

ATAD5 PEX6 PSMC4 TRIP13

2.96e-04341784PS00674
Domain-

DNAH3 ABCC4 ABCA3 ABCA13 ATAD5 NOA1 PEX6 PSMC4 TRIP13 ABCG4 GTPBP8 ABCB10 ABCA5 DDX54 ABCC12 ASCC3 ATP5F1B

8.01e-04746178173.40.50.300
DomainFATC

SMG1 PRKDC

8.86e-0451782PF02260
DomainKinesin_assoc

KIF1A KIF14

1.32e-0361782PF16183
DomainFAT

SMG1 PRKDC

1.32e-0361782PS51189
DomainFATC

SMG1 PRKDC

1.32e-0361782PS51190
DomainKinesin_assoc

KIF1A KIF14

1.32e-0361782IPR032405
DomainFATC_dom

SMG1 PRKDC

1.32e-0361782IPR003152
DomainPIK_FAT

SMG1 PRKDC

1.32e-0361782IPR014009
DomainFATC

SMG1 PRKDC

1.32e-0361782SM01343
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN11A SPTBN4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.14e-11311399M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

6.29e-10321398M27455
PathwayKEGG_ABC_TRANSPORTERS

ABCC4 ABCA3 ABCA13 ABCG4 ABCB10 ABCA5 ABCC12

2.20e-07441397M11911
PathwayREACTOME_L1CAM_INTERACTIONS

SCN11A SPTBN4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.01e-061211399M872
PathwayREACTOME_CARDIAC_CONDUCTION

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A ATP2B2

5.45e-061301399M27454
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCC4 ABCA3 PSMC4 PSMD11 ABCG4 ABCB10 ABCA5

7.02e-051031397M758
PathwayWP_DRAVET_SYNDROME

SCN1A SCN2A SCN3A SCN8A

1.54e-04281394M45519
PathwayREACTOME_MUSCLE_CONTRACTION

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A ATP2B2

1.82e-042031399M5485
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

CNTN4 SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A TPH2 SCN9A ATIC SLC17A6

2.77e-0436713912M48346
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

5.15e-189186816382098
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A

1.79e-129186615746173
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN11A SCN3A SCN5A SCN8A SCN9A

4.15e-125186522875929
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN3A SCN4A SCN5A SCN8A

4.15e-125186517724025
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A SCN3A SCN8A SCN9A

2.48e-116186523652591
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

3.59e-1113186615123669
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN3A SCN8A

7.92e-104186417537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN3A SCN8A

7.92e-104186435031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN3A SCN8A

7.92e-104186429578003
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN3A SCN5A SCN8A

3.18e-0912186530175250
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A SCN3A SCN9A

3.94e-09518648812438
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN3A SCN9A

1.51e-073186319284629
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN3A SCN9A

1.51e-073186333895391
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A SCN3A

1.51e-073186323859570
Pubmed

Where is the spike generator of the cochlear nerve? Voltage-gated sodium channels in the mouse cochlea.

SPTBN4 SCN2A SCN8A

1.51e-073186316033895
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A SCN3A

1.51e-073186312610651
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A SCN3A

1.51e-073186318784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A SCN3A

1.51e-073186317544618
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A SCN8A

1.51e-073186332845893
Pubmed

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.

SCN4A SCN5A SCN9A

1.51e-073186320038812
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A SCN8A

1.51e-073186328518218
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A SCN8A

1.51e-073186317928448
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A SCN3A

1.51e-073186314973256
Pubmed

Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia.

SCN11A SCN8A SCN9A

1.51e-073186315302875
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

KIF1A PEG3 OGDH GRAMD1B MACF1 RIMS1 ADGRL2 ATP2B2

4.76e-07128186830995482
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A SCN3A

6.00e-074186335801810
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A SCN8A

6.00e-074186321156207
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A SCN3A

6.00e-07418638974318
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CEP104 RALGAPA1 TET2 SMG1 DENND2A TBC1D2B BCOR EFR3A ABCA5 HECW2 KDM7A NUP93 ADGRL2 IGSF3

1.13e-065291861414621295
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN2A SCN3A

1.49e-06518631679748
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A SCN3A

1.49e-065186324337656
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SEMA3C KIF1A ATAD5 NOA1 SAMD4B APC NBN RRP8 KAT2A BCOR NDUFS3 CCNC CEP55 EFR3A GPBP1L1 KIF14 MACF1 LSM11 EIF3G HERC2 ASCC3 STX6 ATP5F1B ATP5F1C

1.70e-0614971862431527615
Pubmed

Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.

SCN11A SCN8A SCN9A

2.97e-066186316029194
Pubmed

Are voltage-dependent ion channels involved in the endothelial cell control of vasomotor tone?

SCN11A SCN2A SCN8A

2.97e-066186317513486
Pubmed

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.

SCN11A SCN3A SCN8A

2.97e-066186323711479
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

MTA2 SMG1 CD109 PSMC4 QTRT2 RRP8 PSMD11 TUBGCP4 OGDH TRIP13 SPAG5 GRAMD1B NOP9 DDX54 KIF14 PRKDC NUP93 EIF3G ASCC3 ADGRL2 STX6 ATP5F1B ATP5F1C

3.03e-0614401862330833792
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CCDC14 RALGAPA1 VEZT ATAD5 PSMC4 NBN PSMD11 NIBAN2 BCOR CEP55 EFR3A WWC2 DDX54 KIF14 SENP2 NUP93 HERC2 CDC25B ADGRL2

4.00e-0610491861927880917
Pubmed

A refined map of early gene expression in the dorsal rhombomere 1 of mouse embryos.

GBX2 PHOX2A GDF7 PHOX2B

4.41e-0621186420206242
Pubmed

Defining the membrane proteome of NK cells.

MTA2 ABCC4 PSMC4 ALG11 PSMD11 TUBGCP4 ITGAX CEP55 GRAMD1B BCL2L12 DDX54 KIF14 ATIC PRKDC NUP93 HERC2 ASCC3 IL1RAP ATP5F1B ATP5F1C

5.07e-0611681862019946888
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

EPHB4 RALGAPA1 TMEM126A VEZT ATAD5 PSMC4 NBN RRP8 NIBAN2 OGDH NDUFS3 CEP55 EFR3A GRAMD1B ABCB10 DDX54 ASPM MACF1 SENP2 HERC2 ASCC3 ADGRL2 ATP5F1B

5.13e-0614871862333957083
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN2A SCN8A

5.19e-067186325818041
Pubmed

Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.

SCN1A SCN5A SCN8A

5.19e-067186315272007
Pubmed

Pain without nociceptors? Nav1.7-independent pain mechanisms.

SCN11A SCN3A SCN9A

5.19e-067186324440715
Pubmed

Significant determinants of mouse pain behaviour.

SCN11A SCN3A SCN9A

8.26e-068186325101983
Pubmed

Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins.

SCN1A SCN4A SCN5A

8.26e-06818639412493
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

SMG1 TTLL9 ATAD5 NBN ALG11 RRP8 REV3L BCOR GTF3C5 GUCY1B2 ADAMTS6 PHACTR3 RPS19BP1 IGSF3

9.71e-066381861431182584
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

SCN11A SCN1A SCN3A SCN4A SCN5A SCN8A SCN9A

1.05e-05139186716985003
Pubmed

Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.

SCN1A SCN5A SCN8A

1.23e-059186317884088
Pubmed

Distinct populations of GABAergic neurons in mouse rhombomere 1 express but do not require the homeodomain transcription factor PITX2.

GBX2 PHOX2A PHOX2B SLC17A6

1.26e-0527186421925604
Pubmed

Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1.

TPH2 SLC17A8 PHOX2B SLC17A6

1.26e-0527186420080794
Pubmed

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

TUBGCP4 C4orf54 CATSPER1 GRAP2 RIMS1 NUP93 EIF3G IL1RAP CCDC171 WWC1

1.30e-053311861019490893
Pubmed

The human ATP-binding cassette (ABC) transporter superfamily.

ABCG4 ABCA5 ABCC12

1.76e-0510186311435397
Pubmed

Functional proteomics mapping of a human signaling pathway.

SMG1 DVL3 PEX6 PSMD11 NIBAN2 DENND2B TRAK1 PHACTR3 PKD1 MACF1 HERC2 ASCC3 IL1RAP

1.98e-055911861315231748
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

MTA2 KIF1A CD109 PSMC4 QTRT2 PSMD11 POF1B CEP55 WWC2 DDX54 PRKDC NUP93 ASCC3 CDC25B ADGRL2 WWC1 ATP5F1B

2.11e-059741861728675297
Pubmed

Hoxb1 controls anteroposterior identity of vestibular projection neurons.

PHOX2A PHOX2B SLC17A6

2.41e-0511186322485187
Pubmed

WW and C2 domain-containing proteins regulate hepatic cell differentiation and tumorigenesis through the hippo signaling pathway.

WWC2 WWC1

2.84e-052186229116649
Pubmed

Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.

SCN2A SCN3A

2.84e-052186220346423
Pubmed

Long-lived Min mice develop advanced intestinal cancers through a genetically conservative pathway.

APC NBN

2.84e-052186219584276
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

2.84e-052186237901435
Pubmed

State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.

SCN4A SCN9A

2.84e-052186218079277
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

2.84e-052186226410685
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

2.84e-052186210827969
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

2.84e-052186219694741
Pubmed

Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.

SCN2A SCN8A

2.84e-052186235348308
Pubmed

Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.

SCN2A SCN3A

2.84e-052186211245985
Pubmed

Localization of a human brain sodium channel gene (SCN2A) to chromosome 2.

SPTBN4 SCN2A

2.84e-05218622571571
Pubmed

Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.

SCN2A SCN8A

2.84e-052186215760941
Pubmed

PHOX2A and PHOX2B are differentially regulated during retinoic acid-driven differentiation of SK-N-BE(2)C neuroblastoma cell line.

PHOX2A PHOX2B

2.84e-052186226902400
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

2.84e-05218621317301
Pubmed

The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis.

EPHB4 APC

2.84e-052186219738063
Pubmed

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.

SCN2A SCN3A

2.84e-052186223016767
Pubmed

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

SCN2A SCN3A

2.84e-052186227153334
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

2.84e-052186224990319
Pubmed

Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.

SCN3A SCN9A

2.84e-052186225172946
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

2.84e-052186231439038
Pubmed

KIBRA promotes prostate cancer cell proliferation and motility.

WWC2 WWC1

2.84e-052186227220053
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

2.84e-052186231943325
Pubmed

Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants.

SCN4A SCN5A

2.84e-052186211834499
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

2.84e-052186215249644
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

2.84e-052186227690330
Pubmed

Phenotype-phenotype and genotype-phenotype correlations in patients with idiopathic superior oblique muscle palsy.

PHOX2A PHOX2B

2.84e-052186222170461
Pubmed

Sodium channel slow inactivation interferes with open channel block.

SCN8A SCN9A

2.84e-052186227174182
Pubmed

Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a.

SCN2A SCN8A

2.84e-052186218601978
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

2.84e-052186223965409
Pubmed

Regulation of the Hippocampal Network by VGLUT3-Positive CCK- GABAergic Basket Cells.

SLC17A8 SLC17A6

2.84e-052186228559797
Pubmed

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.

SCN2A SCN8A

2.84e-052186219465131
Pubmed

Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating.

SCN2A SCN5A

2.84e-052186216847056
Pubmed

Specification of the central noradrenergic phenotype by the homeobox gene Phox2b.

PHOX2A PHOX2B

2.84e-052186210736201
Pubmed

Specialized functions of Nav1.5 and Nav1.9 channels in electrogenesis of myenteric neurons in intact mouse ganglia.

SCN11A SCN5A

2.84e-052186224719102
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

2.84e-052186230693367
Pubmed

Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.

SCN2A SCN8A

2.84e-052186223735284
Pubmed

Effects of transcription factors Phox2 on expression of norepinephrine transporter and dopamine beta-hydroxylase in SK-N-BE(2)C cells.

PHOX2A PHOX2B

2.84e-052186219573018
Pubmed

ARIX and PHOX2B polymorphisms in patients with congenital superior oblique muscle palsy.

PHOX2A PHOX2B

2.84e-052186216049556
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

2.84e-052186229649454
Pubmed

Frequency and histological appearance of adenomas in multiple intestinal neoplasia mice are unaffected by severe combined immunodeficiency (scid) mutation.

APC PRKDC

2.84e-05218628567125
Pubmed

Transcriptional regulation of TLX2 and impaired intestinal innervation: possible role of the PHOX2A and PHOX2B genes.

PHOX2A PHOX2B

2.84e-052186217505528
Pubmed

PHOX2A and PHOX2B genes are highly co-expressed in human neuroblastoma.

PHOX2A PHOX2B

2.84e-052186218949361
Pubmed

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.

SCN5A SCN9A

2.84e-052186226861708
Pubmed

The SCID mouse: an experimental model for endometriosis.

MKKS PRKDC

2.84e-052186210601104
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

2.84e-052186233096315
InteractionNALCN interactions

SCN11A PSMD11 SCN1A SCN5A SCN9A

1.01e-07141805int:NALCN
InteractionSCN11A interactions

SCN11A SCN1A SCN5A SCN8A SCN9A

1.50e-07151805int:SCN11A
InteractionCACNA1B interactions

SCN11A SCN1A SCN5A SCN9A RIMS1

1.86e-05371805int:CACNA1B
InteractionSCN8A interactions

SCN11A SCN4A SCN5A SCN8A

2.67e-05201804int:SCN8A
InteractionNEDD4L interactions

SHANK3 MAP3K5 CEP55 SCN1A SCN2A SCN3A SCN5A DDX54 SCN8A SCN9A KIF14 SENP2

3.22e-0532018012int:NEDD4L
InteractionSCN9A interactions

SCN11A SCN1A SCN5A SCN9A

3.27e-05211804int:SCN9A
InteractionSCN4B interactions

SCN1A SCN2A SCN8A

3.80e-0581803int:SCN4B
InteractionYWHAZ interactions

RALGAPA1 TET2 BDP1 SPEG SAMD4B APC TBC1D22B BCOR TERT DENND2B SHANK3 SPAG5 MAP3K5 TRAK1 ITPKA GRAMD1B FSIP2 WWC2 GPBP1L1 KMT5B KIF14 MACF1 HERC2 CDC25B LNX1 ATP2B2 ATP5F1B

4.55e-05131918027int:YWHAZ
InteractionCACNA1D interactions

SCN11A SCN1A SCN5A SCN9A

5.69e-05241804int:CACNA1D
InteractionSCN5A interactions

SCN11A SCN1A SCN5A SCN8A SCN9A

6.09e-05471805int:SCN5A
GeneFamilySodium voltage-gated channel alpha subunits

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

4.82e-17912981203
GeneFamilyATP binding cassette subfamily A

ABCA3 ABCA13 ABCA5

1.22e-04141293805
GeneFamilyPhosphatase and actin regulators

PHACTR2 PHACTR3

3.00e-0441292679
GeneFamilyC2 and WW domain containing

WWC2 WWC1

3.00e-0441292838
GeneFamilyAAA ATPases

ATAD5 PEX6 PSMC4 TRIP13

5.53e-04531294413
GeneFamilyRegulatory factor X family

RFX6 RFX5

1.38e-03812921153
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

BDP1 CNTN4 SYCP2L SEMA3C ABCA3 KIF1A SPEG PEG3 TBC1D2B APC LAMA3 RUSC1 REV3L SHANK3 IKZF4 FSIP2 SCN1A SCN2A SCN3A PHACTR3 SCN8A SCN9A LSM11 RIMS1 GOLGA7B ATP2B2 IGSF3 SLC17A6

4.08e-09110618428M39071
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HSERT

CNTN4 SEMA3C GARNL3 PEG3 SHANK3 GPC3 SCN2A SCN3A PHACTR3 TPH2 SCN9A RIMS1 GOLGA7B ATP2B2

3.93e-0645018414M39072
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HOMTN

CNTN4 SEMA3C ABCA3 GARNL3 RUSC1 PHOX2A SCN3A PHACTR3 SCN8A SCN9A PHOX2B PCBP4 ATP2B2

4.07e-0638918413M39073
CoexpressionGSE25087_FETAL_VS_ADULT_TCONV_UP

PHACTR2 PSMC4 TRIP13 RFX5 NDUFS3 IKZF4 NOP9 ADAMTS6 ATIC

1.22e-051991849M4645
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBGABA

BDP1 CNTN4 SEMA3C PEG3 REV3L CCDC39 IKZF4 SCN1A SCN2A SCN3A PHACTR3 SCN8A SCN9A GOLGA7B ATP2B2 SLC17A6

3.93e-0570318416M39070
CoexpressionFAN_EMBRYONIC_CTX_NSC_2

MKKS ATAD5 TRIP13 SPAG5 CEP55 ASPM LRRCC1 KIF14 CDC25B

4.22e-052331849M39036
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

CEP104 RALGAPA1 TET2 SMG1 PSMD11 KIF14 MACF1 CDC25B

4.23e-051801848M8239
CoexpressionLAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_DN

SH3TC2 PHACTR2 TECRL SHANK3 ARHGEF15 WWC2 ABCA5 CD226 HECW2 GRAP2 MACF1 BANK1 GRAP

4.71e-0549118413MM455
CoexpressionGEORGES_TARGETS_OF_MIR192_AND_MIR215

CCDC14 ATAD5 APC NBN TBC1D22B BCOR SFR1 TRIP13 CEP55 HOXA13 WWC2 ABCB10 ASPM LRRCC1 KIF14 MACF1 HERC2 IL1RAP

6.12e-0589218418M18120
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA2

CNTN4 ABCA3 GARNL3 RUSC1 REV3L IKZF4 SCN2A SCN3A PHACTR3 SCN8A SCN9A RIMS1 SLC17A6

7.34e-0551318413M39069
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

BDP1 CNTN4 SPTBN4 ABCA5 HECW2 SCN2A SCN3A PKD1 SCN8A RIMS1 ADGRL2 ATP2B2

5.42e-112001861248d801219bc771d6c7e151dc88ca4c179988de85
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIF1A RFX6 PHOX2A TMEM132D SCN2A SCN3A SCN8A RIMS1 TMPRSS7 PHOX2B GOLGA7B

4.58e-1018818611c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTN4 SPTBN4 ABCA5 SCN1A SCN2A SCN3A PKD1 SCN8A RIMS1 ADGRL2 ATP2B2

7.93e-1019818611c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTN4 PEG3 SPTBN4 ABCA5 SCN1A SCN2A SCN3A SCN8A RIMS1 ADGRL2 ATP2B2

7.93e-10198186116d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTN4 PEG3 SPTBN4 ABCA5 SCN1A SCN2A SCN3A SCN8A RIMS1 ADGRL2 ATP2B2

7.93e-10198186114ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTN4 PEG3 SPTBN4 ABCA5 HECW2 SCN2A SCN3A SCN8A RIMS1 ADGRL2 ATP2B2

7.93e-10198186110ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTN4 SPTBN4 ABCA5 SCN2A SCN3A PKD1 SCN8A RIMS1 ADGRL2 ATP2B2

1.07e-0819618610676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA3C ABCA3 GARNL3 KIF1A PHOX2A SCN2A SCN3A PHACTR3 PHOX2B PCBP4

1.13e-081971861027c044833e471a312a572e0b1c83e4bc8a36e896
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MKKS SYCP2L CD109 SHANK3 ARHGEF15 MAMSTR ADGRL2 STAG3 TBCC

4.54e-0817118691ae4b6a25bc9c1065cf5d95998ebcc70aee21ab5
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPHB4 SYCP2L CD109 SHANK3 ARHGEF15 ADAMTS6 HECW2 RIMS1 ADGRL2

1.34e-07194186968004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCellPCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating2_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLCO2B1 SHANK3 ARHGEF15 SPAG5 CEP55 ASPM KIF14 CDC25B GRAP

1.52e-0719718698e655db7c6f04d49927a1f0a75178e5955b4af08
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA3C GARNL3 KIF1A PHOX2A SCN3A PHACTR3 SCN9A PHOX2B PCBP4

1.52e-071971869f7eaac1c321710a55e09ffb047a7db2baf7b7e28
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA3 GARNL3 KIF1A PHOX2A SCN3A PHACTR3 SCN9A PHOX2B PCBP4

1.59e-071981869800ade4261695f2efd869d2b1243571de963c431
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma|TCGA-Stomach / Sample_Type by Project: Shred V9

ATAD5 QTRT2 KAT2A TRIP13 SPAG5 CEP55 ASPM KIF14 ATIC

1.66e-071991869b10698aee2e6c17bc559eb4f723024141f914b90
ToppCellTCGA-Stomach-Primary_Tumor|TCGA-Stomach / Sample_Type by Project: Shred V9

ATAD5 QTRT2 KAT2A TRIP13 SPAG5 CEP55 ASPM KIF14 ATIC

1.66e-07199186938f1f612b29feb868322999ceeda78e52447ec4f
ToppCellfacs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 RUBCNL SPAG5 CEP55 SCN4A ASPM KIF14 BANK1

3.31e-0715718680fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG CD109 SHANK3 ARHGEF15 LINC01545 ADAMTS6 ATP2B2 TBCC

5.80e-071691868c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

KIF1A RFX6 SPTBN4 TMEM132D SCN2A SCN3A SCN8A RIMS1

1.02e-06182186857bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D231|Adult / Lineage, Cell type, age group and donor

SYCP2L CD109 SHANK3 ARHGEF15 ADAMTS6 HECW2 RIMS1 ADGRL2

1.15e-06185186807f9f38f0739d7c830641723a38385550ac1ac92
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIF1A RFX6 TMEM132D SCN2A SCN3A SCN8A RIMS1 GOLGA7B

1.20e-061861868b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

ABCC4 ABCA3 ABCA13 DENND2B SCN1A SCN9A POU2F3 WWC1

1.30e-061881868ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellNeuroendocrine-neuroendo-2-Calca|World / Class top

CNTN4 KIF1A SYT17 ARHGEF15 SCN3A SCN8A SCN9A GOLGA7B

1.35e-0618918686baa9a74560121cc008bb8fa9b2b7a335b3aeee0
ToppCellNeuroendocrine|World / Class top

CNTN4 KIF1A SYT17 ARHGEF15 SCN3A SCN8A SCN9A GOLGA7B

1.52e-0619218680199da3ef9ddb6673e9aa41f346f374838aec182
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GARNL3 KIF1A PHOX2A SCN2A SCN5A PHACTR3 SCN9A PHOX2B

1.58e-0619318688851275bcf4ecd6e87a91c8784fc5d76d246ff3b
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SYCP2L CD109 SHANK3 ARHGEF15 ADAMTS6 HECW2 RIMS1 ADGRL2

1.64e-06194186840842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

SYCP2L CD109 SHANK3 ARHGEF15 ADAMTS6 HECW2 RIMS1 ADGRL2

1.64e-06194186871ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellPCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating2_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SHANK3 ARHGEF15 SPAG5 CEP55 ASPM KIF14 CDC25B GRAP

1.84e-061971868491e12a5fca06b86443c0173f5fa750ea3b8a715
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN9 FAM193B KIF1A HOXA13 ASPM CCDC171 STAG3

1.89e-061381867c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MKKS TRIP13 SPAG5 CEP55 BCL2L12 ASPM KIF14 CDC25B

1.91e-0619818681fa213e79d828bff6465bde116536dd1b80d94e0
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Stem_cells-Neuroepithelial_cell|5w / Sample Type, Dataset, Time_group, and Cell type.

ATAD5 TRIP13 SPAG5 CEP55 BCL2L12 GPC3 ASPM KIF14

2.06e-062001868c865efaaaecccbf9c833d6c1cbe85809a3ec306d
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Stem_cells|5w / Sample Type, Dataset, Time_group, and Cell type.

ATAD5 TRIP13 SPAG5 CEP55 BCL2L12 GPC3 ASPM KIF14

2.06e-0620018682ee167b8bddd11fd5b1f61f87fcdf757aee3193e
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Proliferating|6_mon / Sample Type, Dataset, Time_group, and Cell type.

TRIP13 SPAG5 CEP55 ZIC4 GPC3 ASPM KIF14 CDC25B

2.06e-062001868c784459a62bebec560e79aba83de8611457437bc
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Proliferating-Cycling|6_mon / Sample Type, Dataset, Time_group, and Cell type.

TRIP13 SPAG5 CEP55 ZIC4 GPC3 ASPM KIF14 CDC25B

2.06e-062001868322337a5a9cc2de1913ee9258c98ae51fb4bd6bb
ToppCellMS-IIF-Lymphocyte-T/NK-ILC|IIF / Disease, condition lineage and cell class

EPHB4 TTLL9 GRAMD1B GPC3 LRRCC1 DNAI4 LNX1 WWC1

2.06e-062001868edb0b252e6ff9824908d1ff7d0d42710b00949c8
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp4_Mab21l1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA3C GHSR GPC3 TPH2 OR52W1 IGSF3

3.13e-0696186678f19fee755061b4144b1beebb60f4e8bc4dbf0d
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC14 TRIP13 CEP55 GRAMD1B CD226 PHACTR3 KIF14

4.64e-061581867ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIF1A RFX6 TMEM132D SCN2A SCN3A RIMS1 GOLGA7B

4.84e-0615918677747cef94c55144fddcd024a7495318357f1351b
ToppCellIIF-Lymphocyte-T_NK-ILC|IIF / Disease, Lineage and Cell Type

EPHB4 TTLL9 GRAMD1B GPC3 DNAI4 LNX1 WWC1

4.84e-06159186755e4f21548f480ca414c00cbff5ec3b13bafd271
ToppCell10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Liver / Manually curated celltypes from each tissue

SPAG5 CEP55 CD1A BCL2L12 CATSPER1 ASPM KIF14

6.42e-061661867a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCell10x5'-Liver-Hematopoietic_progenitors|Liver / Manually curated celltypes from each tissue

SPAG5 CEP55 CD1A BCL2L12 CATSPER1 ASPM KIF14

6.42e-061661867ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

CAPN9 KIF1A GPR39 LAMA3 NIBAN2 WWC2 IGSF3

7.51e-06170186736c9f7f98612a72dc511c8da4358d67444f6bcf4
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

CAPN9 KIF1A GPR39 LAMA3 NIBAN2 WWC2 IGSF3

7.51e-0617018674cd3b7e43a061948084c01713ae141b5c2c07d89
ToppCellhealthy_donor-Myeloid-Monocytic-Developing_Neutrophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

DPY19L2 SPAG5 CEP55 ASPM KIF14 C2orf92 LNX1

7.51e-061701867cfd7f29805b7c51666b0eaf269c36c96b8765a1a
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SCN11A ATAD5 CEP55 ADAMTS6 GRAP2 ASPM KIF14

7.80e-061711867e3cab55f39879e2bd3e8bda91802181075839bc4
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SCN11A ATAD5 CEP55 ADAMTS6 GRAP2 ASPM KIF14

7.80e-06171186752fdc2a4ec36fb91583b1215362548ceb6740ae1
ToppCellBronchial_Biopsy-Immune-Mast_cells|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

ABCA3 SLCO2B1 ITGAX CATSPER1 ADAMTS6 CD226 GRAP2

8.10e-061721867c477008444d2d71071177807870d7455e90c2fad
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

SLC25A41 SCN11A CYP46A1 SHANK3 ARHGEF15 SCN3A MEDAG

8.10e-061721867d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 TERT TRIP13 SPAG5 CEP55 ASPM IGSF3

8.42e-061731867f38bf7584e08d15a6e2c116b7c3551ba475a5e14
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATAD5 TRIP13 SPAG5 ITPKA CEP55 ASPM KIF14

1.05e-051791867ac987c9425a1b4106d1b8779a2c5461383eae2ae
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GARNL3 KIF1A PHOX2A SCN2A SCN5A SCN9A PHOX2B

1.13e-0518118677f99002a6411117cc2361334c7c9228e20c574b4
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

CAPN9 ABCA3 GPR39 SYT17 LAMA3 WWC2 WWC1

1.21e-0518318677b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZIC4 ADAMTS6 HECW2 SCN1A SCN4A PHOX2B ANKFN1

1.35e-051861867bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRIP13 SPAG5 CEP55 BCL2L12 ASPM KIF14 CDC25B

1.35e-051861867993c58ef4445bf81bbc9b489635883848b5b4c8e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCC4 ABCA3 ABCA13 NIBAN2 SCN1A POU2F3 WWC1

1.35e-051861867acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DENND2A SHANK3 HECW2 SCN3A SCN9A MACF1 GRAP

1.35e-05186186720340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellPCW_05-06-Neuronal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIF1A RUBCNL PHOX2A PHACTR3 SCN9A PHOX2B PCBP4

1.40e-05187186703a2ed85b171c887d4f3b0f4fe2e1cb4a853e658
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1A SCN2A SCN8A MEDAG RIMS1 GOLGA7B ATP2B2

1.40e-0518718677b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PEG3 OGDH SCN2A SCN3A SCN9A RIMS1 GOLGA7B

1.44e-051881867b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 SHANK3 ARHGEF15 HECW2 SCN9A CDC25B ADGRL2

1.44e-05188186773f6ec915934154f435a376cb274b058ff7c5f35
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LAMA3 GBX2 GUCY1B2 GPC3 ADAMTS6 ASPM POU2F3

1.44e-0518818670476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCell367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ATAD5 TRIP13 SPAG5 CEP55 ASPM KIF14 BANK1

1.44e-051881867f5102e8d95506c25c675094b86162a6a50087b64
ToppCellnormal-na-Lymphocytic|normal / PBMC cell types (v2) per disease, treatment status, and sex

ATAD5 TRIP13 SPAG5 CEP55 ASPM KIF14 OR52W1

1.49e-0518918671d382f8eb998c6a30e09fddc9a427afc8f5f7323
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A GPR39 GRAMD1B ABCA5 SCN2A SCN3A ADGRL2

1.49e-051891867975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellnormal-na-Lymphocytic-lymphocyte|normal / PBMC cell types (v2) per disease, treatment status, and sex

ATAD5 TRIP13 SPAG5 CEP55 ASPM KIF14 OR52W1

1.49e-051891867b83fd81ecc5ef363be7435ee12cb7079e2434af7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A GPR39 GRAMD1B ABCA5 SCN2A SCN3A ADGRL2

1.49e-0518918677eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellPBMC-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

DPY19L2 ATAD5 CEP55 SCN1A ASPM PRKDC IGSF3

1.49e-051891867946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCellnormal-na-Lymphocytic-lymphocyte-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

ATAD5 TRIP13 SPAG5 CEP55 ASPM KIF14 OR52W1

1.49e-0518918673db4177d68cab4cd16842d2ebcaca28f69300e44
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCN11A ABCA3 KIF1A PHOX2A SCN5A SCN9A PHOX2B

1.49e-051891867cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A SCN2A SCN5A PHACTR3 TPH2 SCN9A PHOX2B

1.55e-051901867bdbfaced785db79ff965f332759be258dbf743cf
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ABCA3 KIF1A PHOX2A SCN3A SCN9A PHOX2B GOLGA7B

1.60e-0519118673a5081dc542ac6262acfe5f8084a86616fee8082
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

ATAD5 CEP55 GRAMD1B CD226 GRAP2 ASPM KIF14

1.60e-051911867bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A PHOX2A SCN5A SCN9A PHOX2B PCBP4 CCDC171

1.60e-051911867c7b95a5f9185d533c08754ce2e4ce91533eb612e
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GARNL3 KIF1A PHOX2A SCN3A PHACTR3 PHOX2B PCBP4

1.65e-051921867fe9297cb65234d9f511bab1a5dbf2679d5a4cd15
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A PHOX2A SCN5A SCN9A PHOX2B PCBP4 CCDC171

1.65e-05192186756f2388c9c4e19883ae5cff332c77f596ff744a8
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 SHANK3 ARHGEF15 HECW2 SCN9A CDC25B ADGRL2

1.65e-051921867c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)|Adult / Lineage, Cell type, age group and donor

SYCP2L CD109 SHANK3 ARHGEF15 ADAMTS6 HECW2 ADGRL2

1.71e-05193186739c6c96a2a100b1b290a779d36cc6bc17245720b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATAD5 TRIP13 SPAG5 CEP55 BCL2L12 ASPM KIF14

1.71e-051931867cf680afddc08b6481f1b3eee9c57acfaebeac6f0
ToppCellTCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

EPHB4 ITPKA HOXA13 BCL2L12 DDX54 MAMSTR ATP5F1C

1.71e-051931867c0d4da15d973cf6f8daa2b0af84b1baaf8491b83
ToppCell3'_v3-Lung-Myeloid_Mac-Cycling_Myeloid-Mac|Lung / Manually curated celltypes from each tissue

ATAD5 TRIP13 SPAG5 CEP55 ABCG4 ASPM KIF14

1.77e-051941867a8ae49157ca3f9e8b3f1750a995aee012dc859b6
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA3 KIF1A PHOX2A SCN2A SCN5A SCN9A PHOX2B

1.77e-05194186715224fb3e7ca5bd1fb8c41f8275842f737014095
ToppCell(1)_T_cells_Dividing|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ATAD5 TERT TRIP13 SPAG5 CEP55 ASPM KIF14

1.77e-0519418678f313071933451780309d2174ed27d8cdc734343
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ABCC4 ABCA13 LAMA3 PHACTR3 DNAI4 WWC1

1.77e-051941867e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CCDC14 CNTN4 REV3L SPAG5 ASPM KIF14 RIMS1

1.77e-0519418677a66bd7d4fc9c6db861cedd2487f241e406869d1
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RUBCNL SPAG5 CEP55 BCL2L12 ASPM KIF14 CDC25B

1.77e-05194186706b8dc2e46f833707d5b68b324b4ff6c4d0dccf9
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 ABCA3 GPR39 LAMA3 ABCA5 WWC1

1.80e-0513018666434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCellTCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type|TCGA-Adrenal / Sample_Type by Project: Shred V9

EPHB4 ITPKA HOXA13 BCL2L12 DDX54 MAMSTR ATP5F1C

1.83e-051951867c3280bb6219e2eff5e24ef45aa2d76479a562122
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF1A PEG3 RFX6 REV3L ABCA5 MACF1 ASCC3

1.83e-0519518677796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellsevere-B_cell|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYT17 APC ADAMTS6 SCN2A SCN3A STAG3 BANK1

1.83e-0519518670fc3c605609c9e6bdea15d73c45def2188ae5fb1
ToppCellCOVID-19-lung-Proliferative_fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

ATAD5 TRIP13 SPAG5 CEP55 GPC3 ASPM KIF14

1.89e-051961867ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DPY19L2 DENND2B GRAMD1B ABCA5 SCN2A ADGRL2 IGSF3

1.89e-051961867b8350340d86e4524e9616a427e7f2e116a6fb3be
ToppCellControl-Neu_4|Control / 5 Neutrophil clusters in COVID-19 patients

CCDC14 CEP104 BDP1 CEP55 ASPM KIF14 ATP5F1C

1.89e-051961867b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

TRIP13 SPAG5 CEP55 BCL2L12 ASPM KIF14 CDC25B

1.89e-0519618675905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DPY19L2 DENND2B GRAMD1B ABCA5 SCN2A ADGRL2 IGSF3

1.89e-051961867f40d10ea7714067585493fdc89744714aa427de8
ToppCellsevere_COVID-19-T/NK_proliferative|World / disease group, cell group and cell class (v2)

ATAD5 TRIP13 SPAG5 CEP55 BCL2L12 ASPM KIF14

1.95e-051971867189d97a6c2ff8803db8cc05e205c9d88dac3911f
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GARNL3 KIF1A PHOX2A SCN3A PHACTR3 PHOX2B PCBP4

1.95e-051971867fd43fc1cbf0c17b370397d73dddc572565a759c7
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYCP2L CD109 SHANK3 ADAMTS6 HECW2 RIMS1 ADGRL2

1.95e-05197186781718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCell10x5'-GI_large-bowel-Lymphocytic_B-GC_B_(I)|GI_large-bowel / Manually curated celltypes from each tissue

TERT TRIP13 SPAG5 CEP55 BCL2L12 ASPM KIF14

1.95e-05197186780a0cfbd454409594effead7082586b06c2f411a
ToppCellICU-SEP-Lymphocyte-T_NK-T_NK_proliferative|ICU-SEP / Disease, Lineage and Cell Type

ATAD5 TRIP13 SPAG5 CEP55 BCL2L12 ASPM KIF14

1.95e-051971867908e91fa16134b61943aea5e8fc0d6fbac8a8c6e
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ABCC4 ABCA3 LAMA3 CCDC39 SMYD4 SCN1A WWC1

1.95e-0519718671485933986921ff45669d9b7501c8d17050b3e97
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

ABCC4 ABCA3 CCDC39 SMYD4 ABCA5 SCN1A WWC1

1.95e-0519718671a1bee8da6e04b65935c40373eaee4d6c046d9a1
ComputationalGenes in the cancer module 397.

EPHB4 PHACTR2 RUSC1 TRIP13 GRAMD1B HERC2 CDC25B IGSF3

4.43e-051211158MODULE_397
DrugZonisamide

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN9A

3.51e-11171837DB00909
DrugAPETx1, Anthopleura elegantissima

SCN2A SCN3A SCN4A SCN8A

5.98e-0861834ctd:C475726
DrugN-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide

SCN3A SCN4A SCN9A

5.11e-0731833ctd:C561228
Drugbepridil

SPAG5 CATSPER1 SCN3A SCN4A SCN5A PKD1 SCN9A ATP2B2

8.37e-061261838CID000002351
Drugsipatrigine

SCN2A SCN4A SCN9A SLC17A8 SLC17A6

1.12e-05371835CID000060803
DrugScorpion Venoms

SCN2A SCN3A SCN4A SCN9A

1.13e-05181834ctd:D012604
DrugTetrodotoxin

SCN2A SCN3A SCN5A SCN8A SCN9A

1.66e-05401835ctd:D013779
Drugflecainide

SCN11A PEX6 SCN3A SCN4A SCN5A SCN9A

2.31e-05711836CID000003355
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

6.37e-17101778DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

6.37e-17101778DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

6.93e-16121778DOID:0060170 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A ATP12A

6.64e-071631779DOID:1826 (implicated_via_orthology)
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN9A

8.41e-06221774DOID:2030 (implicated_via_orthology)
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A SCN9A

1.74e-0591773C3502809
DiseaseEarly Infantile Epileptic Encephalopathy 6

SCN1A SCN9A

3.58e-0521772C4551549
Diseaseautism spectrum disorder (implicated_via_orthology)

ABCA3 SHANK3 KMT5B SCN1A SCN2A TPH2 RIMS1

3.86e-051521777DOID:0060041 (implicated_via_orthology)
Diseasetransient cerebral ischemia (biomarker_via_orthology)

ADAMTS4 MAP3K5 GHSR SLC17A8 CCR6 ATP5F1B SLC17A6

4.75e-051571777DOID:224 (biomarker_via_orthology)
DiseaseColorectal Neoplasms

TET2 ABCC4 ABCA3 ABCA13 CD109 APC ABCB10 ABCA5 CD226

4.82e-052771779C0009404
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A SCN9A

5.81e-05131773C0751122
DiseaseB Virus Infection

SCN8A SCN9A

1.07e-0431772C0037140
DiseaseBenign familial infantile epilepsy

SCN2A SCN8A

1.07e-0431772cv:C5575231
DiseasePostherpetic neuralgia

SCN8A SCN9A

1.07e-0431772C0032768
DiseaseHerpesviridae Infections

SCN8A SCN9A

1.07e-0431772C0019372
DiseasePrimary Erythermalgia

SCN11A SCN9A

1.07e-0431772C0014805
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN11A SCN9A

1.07e-0431772C1833661
DiseaseProfound Mental Retardation

APC PEX6 SHANK3 SCN1A SCN8A ASCC3

1.99e-041391776C0020796
DiseaseMental Retardation, Psychosocial

APC PEX6 SHANK3 SCN1A SCN8A ASCC3

1.99e-041391776C0025363
DiseaseMental deficiency

APC PEX6 SHANK3 SCN1A SCN8A ASCC3

1.99e-041391776C0917816
DiseaseNeuropathy, Hereditary Sensory And Autonomic, Type IIA

KIF1A SCN9A

2.13e-0441772C2752089
DiseaseHereditary sensory and autonomic neuropathy type 2

KIF1A SCN9A

2.13e-0441772cv:C5574675
DiseaseNeuropathy, hereditary sensory and autonomic, type 2A

KIF1A SCN9A

2.13e-0441772cv:C2752089
DiseaseNEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIA

KIF1A SCN9A

2.13e-0441772201300
DiseaseNeurodevelopmental Disorders

KMT5B SCN1A SCN2A SCN8A RIMS1

2.49e-04931775C1535926
Diseaseneurodegenerative disease (implicated_via_orthology)

DVL3 PSMC4 OGDH TRAK1 SLC17A8 SLC17A6

2.50e-041451776DOID:1289 (implicated_via_orthology)
DiseaseColorectal Carcinoma

TET2 CNTN4 DNAH3 ABCC4 ABCA3 ABCA13 PEG3 CD109 APC GPR87 ABCB10 ABCA5 CD226

3.39e-0470217713C0009402
DiseaseAplastic anemia

NBN TERT

3.54e-0451772cv:C0002874
DiseaseAPLASTIC ANEMIA

NBN TERT

3.54e-0451772609135
DiseaseIntellectual Disability

RALGAPA1 APC PEX6 SHANK3 SCN1A SCN3A SCN8A MACF1 ATIC ASCC3

3.91e-0444717710C3714756
DiseaseClear cell sarcoma of kidney

BCOR TERT

5.28e-0461772C0334488
Disease1-oleoyl-2-docosahexaenoyl-GPC (18:1/22:6) measurement

SYCP2L PEX6

5.28e-0461772EFO_0800449
DiseaseFamilial benign neonatal epilepsy

SCN2A SCN8A

5.28e-0461772C0220669
DiseaseBilateral Wilms Tumor

BCOR TRIP13 GPC3

6.91e-04291773C2930471
DiseaseChild Development Disorders, Specific

CNTN4 KIF1A SHANK3

6.91e-04291773C0085997
DiseaseChild Development Deviations

CNTN4 KIF1A SHANK3

6.91e-04291773C0085996
DiseaseAplastic Anemia

NBN TERT

7.37e-0471772C0002874
DiseaseHypoplastic anemia

NBN TERT

7.37e-0471772C0178416
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

7.37e-0471772C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

7.37e-0471772C0751057
DiseaseCongenital Pain Insensitivity

SCN11A SCN9A

7.37e-0471772C0002768
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN11A SCN9A

7.37e-0471772C0020075
DiseaseDevelopmental Disabilities

CNTN4 KIF1A SHANK3

7.65e-04301773C0008073
DiseaseMalignant neoplasm of breast

IL24 EPHB4 ABCA3 SLCO2B1 NOA1 CD109 DVL3 NBN TERT GALNT16 NDUFS3 NOP9 ABCB10 MACF1 HERC2 SLC17A6

7.85e-04107417716C0006142
Diseasestomach cancer (is_implicated_in)

CAPN9 TET2 APC BCOR

9.37e-04721774DOID:10534 (is_implicated_in)
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A SCN9A

9.78e-0481772C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A SCN9A

9.78e-0481772C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A SCN9A

9.78e-0481772C0338479
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A SCN9A

9.78e-0481772C0751120
DiseaseMyoclonic Encephalopathy

SCN1A SCN9A

9.78e-0481772C0438414
DiseaseMyoclonic Absence Epilepsy

SCN1A SCN9A

9.78e-0481772C0393703
DiseaseLiver carcinoma

APC TERT TRIP13 CEP55 HOXA13 ZIC4 GPC3 ASPM KIF14 IL1RAP

1.03e-0350717710C2239176
DiseaseAutistic Disorder

CNTN4 KIF1A INPP1 APC SHANK3 TPH2 RIMS1

1.05e-032611777C0004352
Diseasetriacylglycerol 58:10 measurement

CNTN4 SCN9A LNX1

1.11e-03341773EFO_0010437
Diseasepit and fissure surface dental caries

CNTN4 BCOR EFR3A

1.21e-03351773EFO_0006338
DiseaseFebrile Convulsions

SCN1A SCN2A

1.25e-0391772C0009952
Diseasecystic fibrosis (implicated_via_orthology)

ABCC4 ABCC12

1.25e-0391772DOID:1485 (implicated_via_orthology)
Diseaseurticaria, response to non-steroidal anti-inflammatory, angioedema

RIMS1 BANK1

1.25e-0391772EFO_0005531, EFO_0005532, EFO_0005533
DiseaseMyoclonic Epilepsy

SCN1A SCN9A

1.25e-0391772C0014550
DiseaseNephroblastoma

BCOR TRIP13 GPC3

1.31e-03361773C0027708
Diseasecalcium measurement

TET2 ABCC4 GPR39 CD109 TBC1D2B ABCG4 KIF14 MACF1 ABCC12 ASCC3 BANK1

1.51e-0362817711EFO_0004838
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A SCN9A

1.56e-03101772C0917800
DiseaseMalignant neoplasm of liver

TTLL9 APC TERT TMEM132D DDX54

1.70e-031421775C0345904
DiseaseLiver neoplasms

TTLL9 APC TERT TMEM132D DDX54

1.70e-031421775C0023903
Diseaseclostridium difficile infection

SLC25A33 APC EFR3A TMEM132D CCDC171

1.80e-031441775EFO_0009130
DiseaseSclerocystic Ovaries

TTLL9 CEP55 SPTBN4 DDX54 ASPM

1.80e-031441775C1136382
DiseasePolycystic Ovary Syndrome

TTLL9 CEP55 SPTBN4 DDX54 ASPM

1.80e-031441775C0032460
Diseaseplatelet crit

TET2 DENND2A DNAH3 ABCC4 INPP1 ZC3HC1 TBC1D22B NIBAN2 TERT ITGAX DENND2B CD226 KDM7A TM2D1

1.88e-0395217714EFO_0007985
DiseaseMyoclonic Astatic Epilepsy

SCN1A SCN9A

1.90e-03111772C0393702
Diseasenervous system disease (implicated_via_orthology)

KIF1A ATP12A

2.27e-03121772DOID:863 (implicated_via_orthology)
DiseaseSudden infant death syndrome

SCN5A PHOX2B

2.27e-03121772C0038644
Diseaselung carcinoma

PHACTR2 ATAD5 RFX6 OGDH TERT CCR6 RIMS1 ADGRL2 IL1RAP

2.63e-034821779EFO_0001071
DiseaseAcute Promyelocytic Leukemia

TET2 BCOR ITGAX

2.67e-03461773C0023487
DiseaseHereditary Motor and Sensory-Neuropathy Type II

KIF1A SCN9A

2.67e-03131772C0270914
DiseaseHamman-Rich syndrome

ABCA3 TERT

3.11e-03141772C0085786
Diseaseserum albumin measurement

SEMA3C TBC1D2B KAT2A TERT ABCG4 BCL2L12 ABCA5 MACF1 LNX1 BANK1

3.18e-0359217710EFO_0004535
Diseasecomplement factor H-related protein 4 measurement

KIF1A ASPM ADGRL2

3.19e-03491773EFO_0600091
DiseaseMedulloblastoma

APC NBN SMYD4

3.38e-03501773C0025149
DiseaseMMR-related febrile seizures

SCN1A SCN2A

3.57e-03151772EFO_0006519
Diseasephosphatidylcholine 36:3 measurement

CCDC39 TMEM132D

3.57e-03151772EFO_0010381
DiseaseDrug-induced agranulocytosis

SCN8A ADGRL2

4.06e-03161772HP_0012235
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

ASPM KIF14

4.06e-03161772DOID:0070296 (is_implicated_in)
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

4.06e-03161772C0393706
DiseaseEpilepsy

SCN1A SCN2A SCN8A SCN9A

4.27e-031091774C0014544
DiseaseCondition, Preneoplastic

TTLL9 TMEM132D DDX54 ATP5F1B

4.41e-031101774C0282313
DiseasePrecancerous Conditions

TTLL9 TMEM132D DDX54 ATP5F1B

4.41e-031101774C0032927
DiseaseVitiligo

IKZF4 CCR6

4.59e-03171772C0042900
DiseaseUterine leiomyoma, estrogen-receptor positive breast cancer

ATAD5 TERT

5.14e-03181772EFO_1000649, HP_0000131
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

5.14e-03181772HP_0002373
Diseaseschizophrenia, inflammatory bowel disease

BCL2L12 BANK1

5.14e-03181772EFO_0003767, MONDO_0005090
DiseaseLibman-Sacks Disease

TERT CD226 BANK1

5.14e-03581773C0242380
Diseaseamyloid-beta measurement

ABCC4 EFR3A PHACTR3 PRKDC ATP12A LNX1 ANKFN1

5.78e-033551777EFO_0005194

Protein segments in the cluster

PeptideGeneStartEntry
RTAFKNRKRAAILTT

ABCA5

1476

Q8WWZ7
VEVEFTSSNKRIRTR

BANK1

226

Q8NDB2
LQIRKSARASVSRFS

ALG11

461

Q2TAA5
RISVIKSVFSSRSLL

ATAD5

1771

Q96QE3
ILFKRTFLSILRDTV

ABCG4

376

Q9H172
TISKVTSNLRIRSRL

BDP1

2086

A6H8Y1
IVRTFRIETRKASKA

EIF3G

81

O75821
AIRVLRRLSFLTSVQ

CATSPER1

556

Q8NEC5
LLRRQTSELEFSTQR

CCDC171

251

Q6TFL3
RSLRLEVTEFKRSVN

CCDC171

991

Q6TFL3
RTTTIAKKRQIFLRD

GRAP

136

Q13588
RLRDQLKARYSTTTL

CEP55

86

Q53EZ4
AIVQATKSFRLRSRT

CCR6

146

P51684
LDNFKTRTRSTVSVR

CNTN4

121

Q8IWV2
TRQLFQRLTVTIKRF

ABCA3

231

Q99758
RKTVLSLRSIVDFTE

ABCA13

2251

Q86UQ4
QRIVNRLRTSLFSSI

ABCB10

241

Q9NRK6
RLRTSLFSSILRQEV

ABCB10

246

Q9NRK6
SKLVRLSSDSFARLV

BCL2L12

236

Q9HB09
TRNIVKFDLRTRIKS

ADGRL2

226

O95490
VSERFLATLLSRVRS

ARHGEF15

471

O94989
RKSVASKSIRRFLEV

DENND2B

1061

P78524
RRKQKVSRIERSSSF

DVL3

221

Q92997
RNRFSEILETSSTKL

BCOR

761

Q6W2J9
AEVTRLRELTRTLQT

CCDC14

631

Q49A88
DRLSRRKSIVDTVSI

EFR3A

691

Q14156
KLERTRFLNVRASAI

ASPM

2991

Q8IZT6
LKFLTRTRSTVAESV

RPS19BP1

76

Q86WX3
RIQTQIRVVKAFRSS

ATP2B2

1136

Q01814
LTRVARNKSRLRVST

GRAMD1B

486

Q3KR37
RQKRSVSIERFVETL

ADAMTS6

241

Q9UKP5
KLTVSRARKIQRFLS

ATP5F1B

451

P06576
RENISTEFRERLSKI

CCDC39

621

Q9UFE4
RSTLLRTVKSVLNRT

GALNT16

136

Q8N428
RDSQLRSQARTLITF

NUP93

781

Q8N1F7
RQTFLLQTTKLTRLA

MTA2

451

O94776
RITARRKLLESVASA

RUBCNL

646

Q9H714
LKRSFSSIVEVARFL

RFX5

216

P48382
VRRFVSSLKRQTSFL

RFX6

376

Q8HWS3
TFQETKNRSLSRVRV

ITGAX

691

P20702
FTVTRRQLLEKFRVE

KAT2A

326

Q92830
SVRKRFFREALLQIS

NIBAN2

486

Q96TA1
TRLIAAATSVLKTRF

CCNC

106

P24863
SRKLVSFTLSDLRAV

HECW2

181

Q9P2P5
KRIREQSSARITISE

PCBP4

41

P57723
RSRKRLETFLSLLVQ

INPP1

376

P49441
TEKTAETRLTLQRRA

KIF14

111

Q15058
ARNVALTTFLKRREA

NOP9

601

Q86U38
QAGTRTFIKELRSRV

KDM7A

116

Q6ZMT4
RVRTTLSVLKRIVTS

MKKS

21

Q9NPJ1
RTKQIRDRLLETFTF

OR52W1

301

Q6IF63
SEESRTARRQTIIFL

GPR39

271

O43194
SRRQSSARRTEKIFL

GPR39

396

O43194
RDSSLTLTRLFDRLK

LSM11

216

P83369
EFTKATNIRLRFLRT

LAMA3

251

Q16787
SVRFLKTSENRAELR

EPHB4

481

P54760
VKSLRSERLIRTSLD

WWC1

976

Q8IX03
LTKLTRRTTDRKSEF

GPBP1L1

311

Q9HC44
SRRRELIQKLKSFIS

GPC3

386

P51654
SQTVARLKDVARRIS

HERC2

1021

O95714
TDETLSFIQKSRRLL

IL1RAP

451

Q9NPH3
LRRSASLATKVFIQR

GOLGA7B

11

Q2TAP0
IADLIIRKTRRNSIF

ATP12A

946

P54707
YITRRSVRTRTNLKE

KMT5B

536

Q4FZB7
RLVDSIKNYRSRATI

DDX54

561

Q8TDD1
RTREIQSSFIKARKS

FSIP2

3876

Q5CZC0
KELETLFRIRTIRSF

CD1A

81

P06126
IRSVLSIASSEERRK

OR51F2

236

Q8NH61
ILRTVLSIASRAERF

OR51G2

226

Q8NGK0
AVETKLQAIFSRARR

PEX6

506

Q13608
RASQLRVLSAITRKF

PEX6

876

Q13608
FERSTIRSRSFKKIN

LNX1

211

Q8TBB1
IRSRSFKKINRALSV

LNX1

216

Q8TBB1
KSQVGTLLFRSRSRL

CDC25B

71

P30305
LSRVRNTASFRKTAE

DSE

761

Q9UL01
RQSSLLFKILSSVRN

TUBGCP4

621

Q9UGJ1
RETSAVLERKISTRQ

PHACTR2

56

O75167
VQELQARRFSSRTTL

DPY19L2

96

Q6NUT2
ERRNLKRTFLLVDSV

GTPBP8

186

Q8N3Z3
TSIETNIRLTLEKRF

POU2F3

286

Q9UKI9
KSLRLVLSTFSNIRE

POF1B

326

Q8WVV4
FKKSNIRTRSESIRS

GPR87

326

Q9BY21
LIRRSSFSDRKFSVT

MEDAG

246

Q5VYS4
RFNSTLVSRKRVLER

PEG3

376

Q9GZU2
RVVKRIQSLASSRTD

MACF1

1066

Q9UPN3
FKTTRSREQVLRVFE

ITPKA

346

P23677
ALAQKLTIRLSSRYR

TRIP13

191

Q15645
RSSLSAKVVAIVSRR

RIMS1

1431

Q86UR5
LRSKTATFTDARIRT

ABCC4

261

O15439
FTNEEKRTLLARLVR

OGDH

246

Q02218
KRTLLARLVRSTRFE

OGDH

251

Q02218
SIKRVRKSVDRSLLF

QTRT2

156

Q9H974
KRFASLSRFVETLVV

ADAMTS4

211

O75173
RLSFETKRISVFIQT

CD109

121

Q6YHK3
NTLRASVFLVRRAIK

CEP104

476

O60308
KNRRRRTAFTSEQLL

GBX2

246

P52951
IITILLVRFKSRNSS

IGSF3

1141

O75054
SFDETRTAVRSITKR

C2orf92

31

A0A1B0GVN3
KQRRVIDLAFSRSSL

CYP46A1

136

Q9Y6A2
KSSAVTVFKLRRQLR

DNAH3

731

Q8TD57
RTLQREAFRKAVSSK

DENND2A

926

Q9ULE3
LVVSRFRELRTTTNL

GHSR

66

Q92847
TSRNYTEIREKLRSR

FAM193B

431

Q96PV7
NRTVEVRTLKSFSTL

IL24

126

Q13007
TEVLTTRIKEIQRRF

LYG1

131

Q8N1E2
SSQRSQIIRSKFRSV

MAMSTR

6

Q6ZN01
SRIAQLLRDTFSSVR

MAPKBP1

1451

O60336
KRERLTSFTDLQVIR

DNAI4

206

Q5VTH9
LTLTFNRTRQAVITK

ATP5F1C

271

P36542
LRRLKRATLNTFLDS

LINC01545

41

Q5VT33
SITTIIVIFLNRRRR

CD226

266

Q15762
SISRQKQIFLRDRTR

GRAP2

136

O75791
ASRARSKTFINLREV

CAPN9

441

O14815
KEVRNLTSRAFRSLA

C4orf54

621

D6RIA3
TFIDRLANSLTKRKR

IKZF4

311

Q9H2S9
SRTVVRDVRLISAKT

NOA1

306

Q8NC60
TLETPTFAQKRRRTL

GARNL3

386

Q5VVW2
TLSTLRYADRAKQIR

KIF1A

341

Q12756
FTQRKVELSKELRRS

KLHL30-AS1

11

Q8NEE0
AVQRFLVSRVTRSLD

PKD1

451

P98161
SLRNKEFKSALRRTI

OR10K1

291

Q8NGX5
IASLREFVRSTDRKI

MAP3K5

1091

Q99683
KRLDVRLSRTSSVER

PHACTR3

321

Q96KR7
RTFTRIFSAKRLVSI

HSFX1

171

Q9UBD0
REVTTFKELRSRSRA

RUSC1

366

Q9BVN2
LLKRRRSDSTLFSTV

SENP2

26

Q9HC62
ISTVATIRASQRIRK

SMYD4

551

Q8IYR2
TRSLRRAETETKVLQ

SPAG5

1076

Q96R06
REKTRLEKFRQLLSS

TBC1D22B

181

Q9NU19
PDRRQKRLIFSTITS

PSMC4

336

P43686
SALRTFRVLRALKTI

SCN4A

216

P35499
AAIFRSLTKRNAVRT

SEMA3C

196

Q99985
RRTLLLTVVDFDKFS

SYT17

271

Q9BSW7
NSLFRRILNVTKARI

TMEM126A

51

Q9H061
ISRNSTEDRFTLRAK

TMEM132D

311

Q14C87
LTEFRSLVIKNSTSR

NBN

656

O60934
NLLSLRFNSRIRVKT

NDUFS3

131

O75489
KRTFLRQALEARLVS

PSMD11

121

O00231
SSRTQRKESLFREIR

GDF7

271

Q7Z4P5
REITRSLFSSRVAEI

SMG1

2456

Q96Q15
SIRRFINSQFVLKTR

GUCY1B2

246

O75343
SALRTFRVLRALKTI

SCN5A

216

Q14524
SALRTFRVLRALKTI

SCN9A

211

Q15858
SIRKAFITSTRQVVR

STX6

86

O43752
TCSRIQTLFRRVKTL

SLC25A41

11

Q8N5S1
RRSLTCIKESLRIFI

SH3TC2

1021

Q8TF17
NVSALRTFRVLRALK

SCN3A

211

Q9NY46
LRERLRKTRFSFNSS

SFR1

51

Q86XK3
AFRRSAILVTDKRVQ

ABCC12

286

Q96J65
FITKDKRRRISATTN

HOXA13

346

P31271
KTRLQSSRLALRTVY

SLC25A33

36

Q9BSK2
NVSALRTFRVLRALK

SCN1A

211

P35498
TRTDRLSLRKTSVNF

ANKFN1

121

Q8N957
RSERPVLVRQSTFIK

APC

2431

P25054
FVSSRRQTRLTALEL

ASCC3

1561

Q8N3C0
SSILREVREKNVRSS

TRAK1

816

Q9UPV9
SLSEKSRKVFRIFRQ

ZC3HC1

481

Q86WB0
DFLRSKQILSTTTVR

SLC17A6

371

Q9P2U8
SLFVRNSTERRSLRV

WWC2

1031

Q6AWC2
LTDIEIVRRVFSSKR

RALGAPA1

391

Q6GYQ0
RLNRSSVSKEVFLSL

REV3L

1776

O60673
LRRQTLTFTTNRLKE

SPEG

3226

Q15772
LTTRLELFTSRFKDR

STAG3

376

Q9UJ98
LLSLLKRVTRTQARF

SAMD4B

26

Q5PRF9
KEVRFVVRSVSARSR

SHANK3

1621

Q9BYB0
RQKESREFLSVSRTV

TMPRSS7

126

Q7RTY8
RELQFRRKVLAVTDS

SLCO2B1

306

O94956
YSSRKKTRTRSNLRI

SYCP2L

531

Q5T4T6
EKRKQRRIRTTFTSA

PHOX2A

86

O14813
RRIRTTFTSAQLKEL

PHOX2A

91

O14813
KTFSRSTKQITFIRI

ZNF274

486

Q96GC6
LRTFRVLRALKTISV

SCN2A

216

Q99250
TRLSITNETFRKTQL

TM2D1

191

Q9BX74
VSALRTFRVLRALKT

SCN8A

216

Q9UQD0
EERFSSLRRLTTIEK

SPTBN4

2101

Q9H254
RFEDVRTFLRAVTKL

RRP8

396

O43159
TKDTRIFLQVTSRAI

TBCC

266

Q15814
TSLETRRQLALKAFT

ATIC

166

P31939
SRKSRRRSSEVEIFV

TPH2

96

Q8IWU9
RLSFTRQSFVDRSLL

PRKDC

1811

P78527
KRLRLYRNTLKESSS

ZIC4

11

Q8N9L1
KEREQRASIRFKTTL

TTLL9

36

Q3SXZ7
LRTFRVFRALKAISV

SCN11A

221

Q9UI33
KRDVSISRLREAFSL

PMS2CL

26

Q68D20
ANRFSTSSLLLRIRK

GTF3C5

76

Q9Y5Q8
ERKRALLSQRATRFI

TECRL

11

Q5HYJ1
SRAFTNLVRKALRLI

VEZT

211

Q9HBM0
SGAIQVLSSFRRKVR

TET2

1441

Q6N021
RKQRRIRTTFTSAQL

PHOX2B

96

Q99453
FTRTILDARKLISIS

TBC1D2B

891

Q9UPU7
AERLTSRVKALFSVL

TERT

651

O14746
YLRSRQILTTTAVRK

SLC17A8

376

Q8NDX2
TTDRLKEIIFRERNS

LRRCC1

471

Q9C099