Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	low voltage-gated calcium channel activity	CACNA1I CACNA1G	1.05e-04	3	119	2	GO:0008332
HumanPheno	Broad alveolar ridges	OFD1 TBC1D24 SH3PXD2B SETBP1 RERE	3.25e-08	15	35	5	HP:0000187
HumanPheno	Abnormal alveolar ridge morphology	OFD1 TBC1D24 SH3PXD2B SETBP1 RERE	2.13e-05	51	35	5	HP:0006477
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	1.00e-06	4	119	3	IPR029423
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	1.00e-06	4	119	3	PF14914
Domain	LRRC37_N	LRRC37A3 LRRC37A2 LRRC37A	1.00e-06	4	119	3	IPR032754
Domain	LRRC37	LRRC37A3 LRRC37A2 LRRC37A	1.00e-06	4	119	3	PF15779
Domain	LRRC37A/B-like	LRRC37A3 LRRC37A2 LRRC37A	1.00e-06	4	119	3	IPR015753
Domain	DUF4704	NBEAL1 NBEAL2 WDFY3	2.50e-06	5	119	3	IPR031570
Domain	DUF4704	NBEAL1 NBEAL2 WDFY3	2.50e-06	5	119	3	PF15787
Domain	PH_BEACH	NBEAL1 NBEAL2 WDFY3	4.97e-06	6	119	3	PF14844
Domain	PH-BEACH_dom	NBEAL1 NBEAL2 WDFY3	1.38e-05	8	119	3	IPR023362
Domain	-	NBEAL1 NBEAL2 WDFY3	1.38e-05	8	119	3	2.30.29.40
Domain	PH_BEACH	NBEAL1 NBEAL2 WDFY3	1.38e-05	8	119	3	PS51783
Domain	BEACH	NBEAL1 NBEAL2 WDFY3	2.06e-05	9	119	3	PS50197
Domain	Beach	NBEAL1 NBEAL2 WDFY3	2.06e-05	9	119	3	PF02138
Domain	-	NBEAL1 NBEAL2 WDFY3	2.06e-05	9	119	3	1.10.1540.10
Domain	Beach	NBEAL1 NBEAL2 WDFY3	2.06e-05	9	119	3	SM01026
Domain	BEACH_dom	NBEAL1 NBEAL2 WDFY3	2.06e-05	9	119	3	IPR000409
Domain	MYB_LIKE	GON4L NCOR2 RERE JPT2	9.78e-05	38	119	4	PS50090
Domain	VDCC_T_a1	CACNA1I CACNA1G	1.20e-04	3	119	2	IPR005445
Domain	AT_hook	CECR2 PRR12 SETBP1	1.33e-04	16	119	3	PF02178
Domain	ZF_ZZ_2	DTNA DMD NBR1	1.92e-04	18	119	3	PS50135
Domain	ZF_ZZ_1	DTNA DMD NBR1	1.92e-04	18	119	3	PS01357
Domain	ZZ	DTNA DMD NBR1	1.92e-04	18	119	3	PF00569
Domain	Znf_ZZ	DTNA DMD NBR1	2.27e-04	19	119	3	IPR000433
Domain	ZnF_ZZ	DTNA DMD NBR1	2.27e-04	19	119	3	SM00291
Domain	SANT	GON4L NCOR2 RERE JPT2	2.88e-04	50	119	4	SM00717
Domain	SANT/Myb	GON4L NCOR2 RERE JPT2	3.35e-04	52	119	4	IPR001005
Domain	EF-hand_dom_typ1	DTNA DMD	5.94e-04	6	119	2	IPR015153
Domain	EF-hand_dom_typ2	DTNA DMD	5.94e-04	6	119	2	IPR015154
Domain	EF-hand_2	DTNA DMD	5.94e-04	6	119	2	PF09068
Domain	EF-hand_3	DTNA DMD	5.94e-04	6	119	2	PF09069
Domain	HMGI/Y_DNA-bd_CS	CECR2 PRR12 SETBP1	9.95e-04	31	119	3	IPR000637
Domain	Myb_DNA-binding	NCOR2 RERE JPT2	1.42e-03	35	119	3	PF00249
Domain	PH_dom-like	NBEAL1 DOK3 FRMPD1 DGKD SH2B1 ARHGEF10L NBEAL2 IRS2 WDFY3	1.63e-03	426	119	9	IPR011993
Domain	VDCCAlpha1	CACNA1I CACNA1G	1.75e-03	10	119	2	IPR002077
Domain	PTBI	DOK3 IRS2	2.13e-03	11	119	2	SM00310
Domain	IRS_PTB	DOK3 IRS2	2.55e-03	12	119	2	PS51064
Domain	WW	NEDD4L ARHGAP39 DMD	3.33e-03	47	119	3	PF00397
Domain	IRS	DOK3 IRS2	3.48e-03	14	119	2	PF02174
Domain	IRS_PTB	DOK3 IRS2	3.48e-03	14	119	2	IPR002404
Domain	DAGKc	SPHK2 DGKD	3.48e-03	14	119	2	SM00046
Domain	WW	NEDD4L ARHGAP39 DMD	3.54e-03	48	119	3	SM00456
Domain	Diacylglycerol_kinase_cat_dom	SPHK2 DGKD	4.00e-03	15	119	2	IPR001206
Domain	DAGK	SPHK2 DGKD	4.00e-03	15	119	2	PS50146
Domain	DAGK_cat	SPHK2 DGKD	4.00e-03	15	119	2	PF00781
Domain	WW_DOMAIN_1	NEDD4L ARHGAP39 DMD	4.20e-03	51	119	3	PS01159
Domain	WW_DOMAIN_2	NEDD4L ARHGAP39 DMD	4.20e-03	51	119	3	PS50020
Domain	WW_dom	NEDD4L ARHGAP39 DMD	4.44e-03	52	119	3	IPR001202
Domain	NAD/diacylglycerol_kinase	SPHK2 DGKD	5.14e-03	17	119	2	IPR016064
Domain	Nucleotide-bd_a/b_plait	ENOX1 RBMXL3 RBM42 TNRC6B ABT1 MCM3AP	6.21e-03	258	119	6	IPR012677
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2	HIPK2 TNRC6B GPRIN1 NCOR2 NOTCH1	3.37e-05	63	83	5	M27862
Pathway	REACTOME_SIGNALING_BY_NOTCH1	HDAC9 NCOR2 TLE1 NEURL1B NOTCH1	7.34e-05	74	83	5	M616
Pathway	REACTOME_RHOU_GTPASE_CYCLE	DLG5 GIT1 ARHGAP30 PEAK1	7.85e-05	39	83	4	MM15607
Pathway	REACTOME_RHOU_GTPASE_CYCLE	DLG5 GIT1 ARHGAP30 PEAK1	8.69e-05	40	83	4	M41816
Pathway	REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	HDAC9 NCOR2 TLE1 NOTCH1	1.78e-04	48	83	4	M611
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SPHK2 FOXK2 HIVEP2 GBF1 OFD1 ZBTB4 RELB TESK1 ARHGEF10L TBC1D24 FAM83H PRR12 NCOR2 SH3PXD2B KCNH2 NBEAL2 MCM3AP CTDP1 SEC16A ANKRD11 IRS2 WDFY3 CABIN1 NOTCH1	9.19e-13	1105	123	24	35748872
Pubmed	Human transcription factor protein interaction networks.	FOXK2 OFD1 DTNA MBNL1 ZBTB9 HIPK2 GON4L TNRC6B RELB ZNF318 KIAA1671 PRR12 NCOR2 CPSF4 FAM120A TRIM9 TLE1 YLPM1 SEC16A RERE CABIN1 L3MBTL3 MNT INO80B	1.87e-10	1429	123	24	35140242
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	DLG5 OFD1 TNRC6B ZNF318 PRR12 NCOR2 MCM3AP SEC16A NBR1 NOTCH1	1.20e-09	184	123	10	32908313
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FOXK2 HIVEP2 NEDD4L DTNA MBNL1 FRMPD1 HIPK2 TNRC6B ARHGAP39 SSPOP SH2B1 KIAA1671 NCOR2 FAM120A SLC35A4 SETBP1 XPNPEP3 ANKRD11 RERE PCDH1 CLEC16A NBR1	1.22e-08	1489	123	22	28611215
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	VGLL3 MBNL1 PRR12 NCOR2 MCM3AP YLPM1 SEC16A L3MBTL3 NOTCH1	1.73e-08	180	123	9	35198878
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	GBF1 TNRC6B PTPN23 TRIM9 SETBP1 SEC16A CACNA1G WDFY3 CLEC16A	1.17e-07	225	123	9	12168954
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A3 LRRC37A2 LRRC37A	1.72e-07	4	123	3	22419166
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZBTB9 TNRC6B ZNF318 KIAA1671 PRR12 NCOR2 TLE1 SEC16A IRS2 RERE L3MBTL3	3.06e-07	418	123	11	34709266
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DLG5 HIVEP2 GBF1 NEDD4L OFD1 GIT1 TESK1 FAM83H KIAA1671 SH3PXD2B TRIM9 SEC16A ANKRD11 IRS2 PEAK1	4.18e-07	861	123	15	36931259
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DLG5 CECR2 KIAA1549 ARHGEF10L TBC1D24 FMNL3 TRIM9 NBEAL2 SETBP1 CACNA1G L3MBTL3 NBR1	4.22e-07	529	123	12	14621295
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	DLG5 KIAA1549 TNRC6B ZNF318 KIAA1671 TRIM9 SEC16A PEAK1 NBR1	4.38e-07	263	123	9	34702444
Pubmed	Interaction network of human early embryonic transcription factors.	FOXK2 HIVEP2 ZBTB9 KIAA1671 PRR12 NCOR2 TLE1 MCM3AP SEC16A RERE	5.27e-07	351	123	10	38297188
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	DLG5 OFD1 TNRC6B KIAA1671 FAM120A SEC16A PEAK1 NBR1	8.48e-07	209	123	8	36779422
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	OFD1 DTNA KIAA1549 PTPN23 ARHGAP39 GPRIN1 KIAA1671 NCOR2 TRIM11 YLPM1 SEC16A PEAK1 DMD L3MBTL3 NBR1 NOTCH1	9.68e-07	1049	123	16	27880917
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	FOXK2 HIVEP2 FOXN4 DTX3 MBNL1 RELB ZNF318 CPSF4 PIAS3 PRICKLE3 TRIM9 ZNF580 MNT	1.48e-06	709	123	13	22988430
Pubmed	BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.	DLG5 HIVEP2 GBF1 OFD1 TNRC6B FAM120A TRIM9 IRS2	1.52e-06	226	123	8	25900982
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HDAC9 GBF1 ZBTB4 PTPN23 DGKD ARHGAP39 SH2B1 PRR12 FAM120A SACS PEAK1	1.54e-06	493	123	11	15368895
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	DLG5 LRRC37A3 SSPOP LRRC37A NBEAL2 MCM3AP	2.09e-06	105	123	6	9628581
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CECR2 ZBTB9 KIAA1549 TNRC6B ZNF318 C11orf16 FAM83H KIAA1671 NCOR2 FAM120A MCM3AP SEC16A IRS2 RERE WDFY3 INO80B	2.15e-06	1116	123	16	31753913
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXK2 GBF1 SF3A1 FRMPD1 RELB SH2B1 NCOR2 FAM120A TLE1 CABIN1 L3MBTL3 NBR1 MNT NOTCH1	2.21e-06	857	123	14	25609649
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	HDAC9 ELOA2 HIVEP2 ZBTB9 RELB NCOR2 PIAS3 DACH2 PRICKLE3 MZF1 TLE1 ZNF580 RERE L3MBTL3	2.88e-06	877	123	14	20211142
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	GBF1 NEDD4L RELB SH2B1 KIAA1671 NCOR2 PIAS3 SETBP1 YLPM1 NOTCH1	3.26e-06	430	123	10	35044719
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	GBF1 GIT1 SF3A1 ZNF318 ARHGAP39 GPRIN1 NCOR2 PRICKLE3 YLPM1 CTDP1 SEC16A IRS2 RERE	3.86e-06	774	123	13	15302935
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A3 LRRC37A2 LRRC37A	5.09e-06	10	123	3	23064749
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	FOXK2 MBNL1 TNRC6B FAM83H PRR12 NCOR2 TLE1 MCM3AP YLPM1 SEC16A	5.56e-06	457	123	10	32344865
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	SPHK2 FOXK2 ELOA2 RBM42 ZBTB9 FAM120A CABIN1 L3MBTL3	7.59e-06	281	123	8	24163370
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	ELOA2 DTNA RBM42 TNRC6B SSPOP TDRD7 SACS CACNA1G RERE NBR1 NOTCH1	1.12e-05	608	123	11	16713569
Pubmed	Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases.	HDAC9 SETBP1 SLC14A2	1.20e-05	13	123	3	22693459
Pubmed	Tumor Suppressor HIPK2 Regulates Malignant Growth via Phosphorylation of Notch1.	HIPK2 NOTCH1	1.24e-05	2	123	2	27335110
Pubmed	Ubiquitination Destabilizes Protein Sphingosine Kinase 2 to Regulate Glioma Malignancy.	SPHK2 NEDD4L	1.24e-05	2	123	2	34305532
Pubmed	Muscarinic receptor activation increases hERG channel expression through phosphorylation of ubiquitin ligase Nedd4-2.	NEDD4L KCNH2	1.24e-05	2	123	2	24688054
Pubmed	Contribution of postsynaptic T-type calcium channels to parallel fibre-Purkinje cell synaptic responses.	CACNA1I CACNA1G	1.24e-05	2	123	2	26627919
Pubmed	Abnormal splicing switch of DMD's penultimate exon compromises muscle fibre maintenance in myotonic dystrophy.	MBNL1 DMD	1.24e-05	2	123	2	26018658
Pubmed	Absence of glial α-dystrobrevin causes abnormalities of the blood-brain barrier and progressive brain edema.	DTNA DMD	1.24e-05	2	123	2	23043099
Pubmed	The human protein kinase HIPK2 phosphorylates and downregulates the methyl-binding transcription factor ZBTB4.	ZBTB4 HIPK2	1.24e-05	2	123	2	19448668
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NEDD4L FRMPD1 GON4L TNRC6B SEMA6D MCM3AP SEC16A RERE CLEC16A	1.53e-05	407	123	9	12693553
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXK2 HIVEP2 FOXN4 ZBTB4 KIAA1549 GON4L RELB DACH2 MZF1 BHLHE22 SETBP1 RERE MNT	2.10e-05	908	123	13	19274049
Pubmed	Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.	ZFAT ARHGAP39 SH2B1 SEMA6D RERE	2.18e-05	94	123	5	25201988
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	NEDD4L ERN1 TNRC6B DGKD NCOR2 ANKRD11 RERE WDFY3 PEAK1 NBR1	2.20e-05	536	123	10	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	NEDD4L ERN1 TNRC6B DGKD NCOR2 ANKRD11 RERE WDFY3 PEAK1 NBR1	2.27e-05	538	123	10	10512203
Pubmed	Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.	PIK3AP1 GIT1 SH3PXD2B IRS2 PEAK1	3.38e-05	103	123	5	21706016
Pubmed	Dystrobrevin and dystrophin: an interaction through coiled-coil motifs.	DTNA DMD	3.71e-05	3	123	2	9356463
Pubmed	Ethanol inhibition of a T-type Ca²+ channel through activity of protein kinase C.	CACNA1I CACNA1G	3.71e-05	3	123	2	23488970
Pubmed	Identification of the t-type calcium channel (Ca(v)3.1d) in developing mouse heart.	CACNA1I CACNA1G	3.71e-05	3	123	2	11230107
Pubmed	Protective role of microRNA-374 against myocardial ischemia-reperfusion injury in mice following thoracic epidural anesthesia by downregulating dystrobrevin alpha-mediated Notch1 axis.	DTNA NOTCH1	3.71e-05	3	123	2	30565678
Pubmed	Specific Knockout of Notch-1 in Macrophages Modulate the Progression of Hepatic Insulin Resistance in HFD Fed Mice via Regulating IRE1α-XBP1 Signals.	ERN1 NOTCH1	3.71e-05	3	123	2	38720211
Pubmed	Dystrophins in vertebrates and invertebrates.	DTNA DMD	3.71e-05	3	123	2	9499411
Pubmed	Cerebellar synaptic defects and abnormal motor behavior in mice lacking alpha- and beta-dystrobrevin.	DTNA DMD	3.71e-05	3	123	2	16540561
Pubmed	Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.	CACNA1I CACNA1G	3.71e-05	3	123	2	33547341
Pubmed	Calmodulin regulates Cav3 T-type channels at their gating brake.	CACNA1I CACNA1G	3.71e-05	3	123	2	28972185
Pubmed	Dystrobrevin increases dystrophin's binding to the dystrophin-glycoprotein complex and provides protection during cardiac stress.	DTNA DMD	3.71e-05	3	123	2	25158611
Pubmed	Growth differentiation factor-15 promotes glutamate release in medial prefrontal cortex of mice through upregulation of T-type calcium channels.	CACNA1I CACNA1G	3.71e-05	3	123	2	27353765
Pubmed	Interaction of α-catulin with dystrobrevin contributes to integrity of dystrophin complex in muscle.	DTNA DMD	3.71e-05	3	123	2	22577143
Pubmed	The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.	ERN1 DMD	3.71e-05	3	123	2	34812145
Pubmed	Role for alpha-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies.	DTNA DMD	3.71e-05	3	123	2	10559919
Pubmed	Spatial distribution and molecular dynamics of dystrophin glycoprotein components at the neuromuscular junction in vivo.	DTNA DMD	3.71e-05	3	123	2	28364093
Pubmed	Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice.	CACNA1I CACNA1G	3.71e-05	3	123	2	11897840
Pubmed	The role of Notch signaling in muscle progenitor cell depletion and the rapid onset of histopathology in muscular dystrophy.	DMD NOTCH1	3.71e-05	3	123	2	25678553
Pubmed	[Molecular mechanism of SH2B1 in regulating JAK2/IRS2 during obesity development].	SH2B1 IRS2	3.71e-05	3	123	2	20360640
Pubmed	T-type channels: release a brake, engage a gear.	CACNA1I CACNA1G	3.71e-05	3	123	2	26488564
Pubmed	SH2B1 enhances insulin sensitivity by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of insulin receptor substrate proteins.	SH2B1 IRS2	3.71e-05	3	123	2	19542202
Pubmed	The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L.	NEDD4L NOTCH1	3.71e-05	3	123	2	29662198
Pubmed	Differential interactions of Na+ channel toxins with T-type Ca2+ channels.	CACNA1I CACNA1G	3.71e-05	3	123	2	18591418
Pubmed	Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation.	CACNA1I CACNA1G	3.71e-05	3	123	2	28846697
Pubmed	Consequences of MEGF10 deficiency on myoblast function and Notch1 interactions.	DMD NOTCH1	3.71e-05	3	123	2	28498977
Pubmed	Cell surface expression of human ether-a-go-go-related gene (hERG) channels is regulated by caveolin-3 protein via the ubiquitin ligase Nedd4-2.	NEDD4L KCNH2	3.71e-05	3	123	2	22879586
Pubmed	Global genetic deletion of CaV3.3 channels facilitates anaesthetic induction and enhances isoflurane-sparing effects of T-type calcium channel blockers.	CACNA1I CACNA1G	3.71e-05	3	123	2	33299036
Pubmed	Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability.	CACNA1I CACNA1G	3.71e-05	3	123	2	11927664
Pubmed	Increased cAMP in monocytes augments Notch signaling mechanisms by elevating RBP-J and transducin-like enhancer of Split (TLE).	TLE1 NOTCH1	3.71e-05	3	123	2	23775085
Pubmed	beta-dystrobrevin, a member of the dystrophin-related protein family.	DTNA DMD	3.71e-05	3	123	2	9419360
Pubmed	Regulation of the human ether-a-go-go-related gene (hERG) channel by Rab4 protein through neural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2).	NEDD4L KCNH2	3.71e-05	3	123	2	23792956
Pubmed	Maturation and maintenance of the neuromuscular synapse: genetic evidence for roles of the dystrophin--glycoprotein complex.	DTNA DMD	3.71e-05	3	123	2	10719885
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	DLG5 DTNA SF3A1 TNRC6B PTPN23 ARHGAP39 GPRIN1 SEC16A IRS2 PEAK1 NOTCH1	4.51e-05	708	123	11	39231216
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	HDAC9 TNFRSF25 HIVEP2 GIT1 ZBTB4 SH2B1 VPS9D1 FAM120A PIAS3 SACS TRIM9 YLPM1 WDFY3 USPL1 CABIN1	5.04e-05	1285	123	15	35914814
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	PIK3AP1 DLG5 OFD1 GIT1 TNRC6B PTPN23 FAM83H KIAA1671 SH3PXD2B FAM120A CLEC16A JPT2	5.24e-05	853	123	12	28718761
Pubmed	Genomic analysis of mouse retinal development.	FOXN4 DTNA MBNL1 TDRD7 NCOR2 FAM120A PIAS3 BHLHE22 WDFY3 JPT2 MNT NOTCH1 IPMK	6.00e-05	1006	123	13	15226823
Pubmed	Characterization of the pVHL Interactome in Human Testis Using High-Throughput Library Screening.	TDRD7 ZNF668 ANKRD11 RERE	6.65e-05	61	123	4	35205757
Pubmed	Pharmacogenetics of antiepileptic drug efficacy in childhood absence epilepsy.	CACNA1I CACNA1G	7.41e-05	4	123	2	28165634
Pubmed	RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD1.	L3MBTL3 NOTCH1	7.41e-05	4	123	2	29030483
Pubmed	Wnt5a controls Notch1 signaling through CaMKII-mediated degradation of the SMRT corepressor protein.	NCOR2 NOTCH1	7.41e-05	4	123	2	22888005
Pubmed	Differential targeting of nNOS and AQP4 to dystrophin-deficient sarcolemma by membrane-directed alpha-dystrobrevin.	DTNA DMD	7.41e-05	4	123	2	18057022
Pubmed	SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function.	NCOR2 NOTCH1	7.41e-05	4	123	2	10713164
Pubmed	Regulation of the human ether-a-go-go-related gene (hERG) potassium channel by Nedd4 family interacting proteins (Ndfips).	NEDD4L KCNH2	7.41e-05	4	123	2	26363003
Pubmed	Syntrophin binds directly to multiple spectrin-like repeats in dystrophin and mediates binding of nNOS to repeats 16-17.	DTNA DMD	7.41e-05	4	123	2	29790927
Pubmed	Dach2-Hdac9 signaling regulates reinnervation of muscle endplates.	HDAC9 DACH2	7.41e-05	4	123	2	26483211
Pubmed	Characterisation of alpha-dystrobrevin in muscle.	DTNA DMD	7.41e-05	4	123	2	9701558
Pubmed	Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis.	DTX3 NOTCH1	7.41e-05	4	123	2	11226752
Pubmed	4E-BP2/SH2B1/IRS2 Are Part of a Novel Feedback Loop That Controls β-Cell Mass.	SH2B1 IRS2	7.41e-05	4	123	2	27217487
Pubmed	Syntrophin binds to an alternatively spliced exon of dystrophin.	DTNA DMD	7.41e-05	4	123	2	7844150
Pubmed	Nedd4-2-dependent ubiquitylation and regulation of the cardiac potassium channel hERG1.	NEDD4L KCNH2	7.41e-05	4	123	2	21463633
Pubmed	Stage-specific effects of Notch activation during skeletal myogenesis.	DMD NOTCH1	7.41e-05	4	123	2	27644105
Pubmed	The functional interactome landscape of the human histone deacetylase family.	HDAC9 SF3A1 NCOR2 YLPM1 SEC16A ANKRD11 RERE	7.95e-05	289	123	7	23752268
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	GIT1 DTNA SF3A1 ARHGAP30 ARHGAP39 ARHGEF10L KIAA1671 CPSF4 SEC16A PEAK1 DMD JPT2	1.03e-04	916	123	12	32203420
Pubmed	A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.	OFD1 DTNA TNRC6B FAM83H KIAA1671 YLPM1 NBR1	1.04e-04	302	123	7	30561431
Pubmed	Prolyl isomerase Pin1 and protein kinase HIPK2 cooperate to promote cortical neurogenesis by suppressing Groucho/TLE:Hes1-mediated inhibition of neuronal differentiation.	HIPK2 TLE1	1.23e-04	5	123	2	24270405
Pubmed	G-Protein-Coupled Receptor-2-Interacting Protein-1 Controls Stalk Cell Fate by Inhibiting Delta-like 4-Notch1 Signaling.	GIT1 NOTCH1	1.23e-04	5	123	2	27926858
Pubmed	NKX2-5, a modifier of skeletal muscle pathology due to RNA toxicity.	MBNL1 DMD	1.23e-04	5	123	2	25168381
Pubmed	Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology.	DTNA DMD	1.23e-04	5	123	2	24014171
Pubmed	Targeted splice sequencing reveals RNA toxicity and therapeutic response in myotonic dystrophy.	MBNL1 DMD	1.23e-04	5	123	2	33503262
Pubmed	SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin.	SH2B1 IRS2	1.23e-04	5	123	2	15316008
Interaction	TOP3B interactions	SPHK2 FOXK2 HIVEP2 GBF1 OFD1 ZBTB4 TNRC6B RELB TESK1 ARHGEF10L TBC1D24 FAM83H PRR12 NCOR2 SH3PXD2B FAM120A KCNH2 NBEAL2 MCM3AP CTDP1 SEC16A ANKRD11 IRS2 WDFY3 CABIN1 NOTCH1	4.16e-07	1470	120	26	int:TOP3B
Interaction	TLE3 interactions	HIVEP2 CECR2 MBNL1 ZBTB4 ZNF318 FAM83H PRR12 NCOR2 TLE1 MCM3AP RERE NOTCH1	2.58e-06	376	120	12	int:TLE3
Interaction	DTX2 interactions	VGLL3 DTX3 MBNL1 DOK3 PRR12 NCOR2 MCM3AP YLPM1 SEC16A L3MBTL3 NOTCH1	4.56e-06	330	120	11	int:DTX2
Interaction	EGR2 interactions	HIVEP2 ZBTB9 PRR12 NCOR2 TLE1 SEC16A RERE JPT2	8.55e-06	171	120	8	int:EGR2
Interaction	LZTS2 interactions	DLG5 OFD1 GIT1 HIPK2 TNRC6B ABT1 FAM83H KIAA1671 CPSF4 SEC16A ANKRD11 CLEC16A INO80B	1.16e-05	512	120	13	int:LZTS2
Interaction	ALG13 interactions	TNRC6B PRR12 NCOR2 FAM120A TLE1 SEC16A RERE WDFY3	1.40e-05	183	120	8	int:ALG13
Interaction	AMOT interactions	DLG5 FOXK2 NEDD4L OFD1 KIAA1549 TNRC6B KIAA1671 CTDP1 SEC16A NBR1	1.77e-05	312	120	10	int:AMOT
Interaction	SMG7 interactions	OFD1 TNRC6B ZNF318 PRR12 NCOR2 FAM120A TLE1 YLPM1 SEC16A CLEC16A	2.14e-05	319	120	10	int:SMG7
Interaction	TRIM37 interactions	DLG5 ELOA2 NEDD4L OFD1 TNRC6B ZNF318 FAM83H PRR12 NCOR2 MCM3AP SEC16A ANKRD11 NBR1 NOTCH1	2.34e-05	630	120	14	int:TRIM37
Interaction	NCK2 interactions	PIK3AP1 GIT1 DTX3 ARHGAP39 FAM83H SH3PXD2B YLPM1 PEAK1 MNT	2.75e-05	262	120	9	int:NCK2
Interaction	ZYX interactions	DLG5 FOXK2 GBF1 HIPK2 TNRC6B PTPN23 KIAA1671 SEC16A PEAK1 NBR1	2.78e-05	329	120	10	int:ZYX
Interaction	TRIM66 interactions	ZNF318 FAM83H KIAA1671 FAM120A MCM3AP SEC16A IRS2 WDFY3	3.17e-05	205	120	8	int:TRIM66
Interaction	SAV1 interactions	DLG5 OFD1 TNRC6B ABT1 FAM83H SEC16A CLEC16A	3.38e-05	151	120	7	int:SAV1
Interaction	WWTR1 interactions	HDAC9 TNRC6B PTPN23 ABT1 ZNF318 GPRIN1 KIAA1671 SH3PXD2B SEC16A PEAK1 NOTCH1	4.47e-05	422	120	11	int:WWTR1
Interaction	ODF2 interactions	DLG5 OFD1 TNRC6B FAM83H KIAA1671 TRIM9 INO80B	4.52e-05	158	120	7	int:ODF2
Interaction	MEX3B interactions	OFD1 GIT1 TNRC6B TDRD7 KIAA1671 FAM120A SEC16A NBR1	5.58e-05	222	120	8	int:MEX3B
Interaction	VASP interactions	OFD1 TNRC6B PTPN23 KIAA1671 TRIM9 SEC16A IRS2 PEAK1 NBR1	6.73e-05	294	120	9	int:VASP
Interaction	TEAD1 interactions	VGLL3 FOXK2 ZBTB9 PRR12 NCOR2 TLE1 L3MBTL3	8.93e-05	176	120	7	int:TEAD1
Interaction	GOLGA1 interactions	DLG5 GBF1 OFD1 KIAA1671 SEC16A PEAK1 NBR1	1.14e-04	183	120	7	int:GOLGA1
Interaction	ENTR1 interactions	DLG5 OFD1 GIT1 TNRC6B PTPN23 KIAA1671 CLEC16A	1.35e-04	188	120	7	int:ENTR1
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 NBEAL2 WDFY3	5.66e-06	9	75	3	1230
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	DTNA DMD NBR1	5.35e-05	18	75	3	91
GeneFamily	Ataxins\|Trinucleotide repeat containing	TNRC6B NCOR2 BHLHE22	1.48e-04	25	75	3	775
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	GON4L NCOR2 RERE	1.38e-03	53	75	3	532
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFAT HIVEP2 ZBTB4 ZBTB9 ZNF318 ZNF710 ZNF668 MZF1 ZNF580	2.82e-03	718	75	9	28
GeneFamily	Calcium voltage-gated channel subunits	CACNA1I CACNA1G	5.17e-03	26	75	2	253
Coexpression	RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN	HIVEP2 OFD1 DTNA MBNL1 ZBTB4 LRRC37A2 HIPK2 GON4L TNRC6B PGF TBC1D24 KIAA1671 FMNL3 RERE DMD CABIN1	1.24e-06	807	123	16	M16651
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	HDAC9 VGLL3 NBEAL1 DTNA MBNL1 ARHGEF10L DMD	9.72e-07	189	123	7	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3AP1 HDAC9 CECR2 DOK3 DGKD TRIM11 IRS2	1.16e-06	194	123	7	11709704079f24a730476572dc2f01e9d2226e2c
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3AP1 HDAC9 CECR2 DOK3 DGKD TRIM11 IRS2	1.16e-06	194	123	7	3a1f95639d5f239f001bd67d4213e8938e7f299d
ToppCell	Sepsis-URO\|Sepsis / Disease, condition lineage and cell class	PIK3AP1 NBEAL1 HIPK2 SH3PXD2B NBEAL2 IRS2 WDFY3	1.37e-06	199	123	7	8e6dac82d1d0e759cd567f9c95b70cb4801d7caf
ToppCell	mild-B_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HDAC9 DGKD ZNF318 TLE1 SETBP1 C12orf42 RERE	1.42e-06	200	123	7	222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOXN4 DTNA CECR2 KIAA1549 FAM83H ZNF668	7.59e-06	169	123	6	606aa4ff25380d9470ec116ca86cd20f8b19587a
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOXN4 DTNA CECR2 KIAA1549 FAM83H ZNF668	7.59e-06	169	123	6	052aae2af5446a0de071d5dda5381b0b9a0ed54d
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	ZBTB4 HIPK2 TNRC6B TMED8 WDFY3 NBR1	9.89e-06	177	123	6	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC37A3 HIPK2 TLE1 SETBP1 RERE SLC14A2	1.48e-05	190	123	6	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	343B-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PIK3AP1 ZBTB4 TBC1D24 MZF1 SETBP1 L3MBTL3	1.57e-05	192	123	6	445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-memory_B_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PIK3AP1 NBEAL1 DOK3 HIPK2 TLE1 SETBP1	1.66e-05	194	123	6	f0c113edb706d53792892115b67277a285219942
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	NEDD4L LRRC37A3 RERE WDFY3 PEAK1 DMD	1.87e-05	198	123	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	HIPK2 KIAA1549 FAM120A IRS2 DMD NOTCH1	1.92e-05	199	123	6	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal-Mesoderm\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	ERN1 LRRC37A2 FMNL3 KCNH2 PCDH1 IPMK	1.97e-05	200	123	6	0f4b8b0868bda406fe6bf01d1b722510fdfd0168
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-7\|TCGA-Bladder / Sample_Type by Project: Shred V9	DOK3 ESPNL DGKD FMNL3 CACNA1G	6.07e-05	150	123	5	3ab17045b2c43bb4f0ebba6aa0cfb22e076a24f9
ToppCell	E16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FOXK2 DOK3 ARHGAP30 NBEAL2 MCM3AP	6.66e-05	153	123	5	6a2a2379238133ce0ad714af130ffe02dd317247
ToppCell	E16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FOXK2 DOK3 ARHGAP30 NBEAL2 MCM3AP	6.66e-05	153	123	5	faa442dd925b2b09919e93c492ccc3f19803ad24
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNFRSF25 LRRC37A2 SACS PRR33 SETBP1	7.30e-05	156	123	5	a5930b455e5c8586c43c50106ab4d8a1e5e9e3d6
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HDAC9 KIAA1549 KCNH2 NEURL1B DMD	8.48e-05	161	123	5	8ec923c230a7a3cce5edf2a736b3a00d607c698a
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-ILC3\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TNFRSF25 ERN1 FRMPD1 TLE1 CRACDL	8.48e-05	161	123	5	584e44e6048c2678eb72cd23a86f48f2466c5da4
ToppCell	normal-na-Lymphocytic_B-B_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ENPP7 NEDD4L DGKD ARHGAP39 TLE1	8.73e-05	162	123	5	ae292318d339305932457bb0e91430594f7a3dfa
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	HDAC9 DGKD TLE1 SETBP1 RERE	8.98e-05	163	123	5	6bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOK3 ARHGAP30 MZF1 TMED8 CACNA1G	1.01e-04	167	123	5	f5bffa77061baec0ba87bd688a047595f32534db
ToppCell	Control-B_cells-Activated_B_cells\|Control / group, cell type (main and fine annotations)	PIK3AP1 HDAC9 TNRC6B SETBP1 C12orf42	1.04e-04	168	123	5	a7159a35fe37f8c241cf8d391debe271e0698105
ToppCell	Mild/Remission-B_naive-4\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MBNL1 DGKD ZNF318 IRS2 RERE	1.06e-04	169	123	5	c3a6179a64589a370108fea809b157839347759c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 HDAC9 ZFAT ERN1 FMNL3	1.13e-04	171	123	5	af1c93eb75f45c042ea475d93db56e4da207e31f
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	DTNA KCNH2 SETBP1 NEURL1B DMD	1.16e-04	172	123	5	c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-Alox5+_Lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF25 ERN1 OFD1 ZC3HC1 DACH2	1.22e-04	174	123	5	a8bd1fa08bf061a627529a38e5a23a68b6d80697
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF25 ERN1 OFD1 ZC3HC1 DACH2	1.22e-04	174	123	5	7f8f6a15a823809effd37c1a5b09ef19b6d67755
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXN4 C11orf16 SSPOP DACH2 CRACDL	1.22e-04	174	123	5	f1510b0f7771936adf29ae3572feab55db31832b
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXN4 C11orf16 SSPOP DACH2 CRACDL	1.22e-04	174	123	5	5d5d2fc60afff47f997751e8e9ca1367a22d19ec
ToppCell	COVID-19-kidney-REN+Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HDAC9 NBEAL1 PGF TRIM9 SETBP1	1.22e-04	174	123	5	8393f0b43c767839c1630bcb952d62b42efc788d
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	HDAC9 ZFAT ERN1 SETBP1 ANKRD11	1.25e-04	175	123	5	37c2d4e0b6e9a3171931797ce9a54f3347288e57
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	FRMPD1 GPRIN1 DACH2 TRIM9 KCNH2	1.25e-04	175	123	5	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	FRMPD1 GPRIN1 DACH2 TRIM9 KCNH2	1.25e-04	175	123	5	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	facs-MAT-Fat-3m-Lymphocytic-T_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF25 ERN1 DACH2 SACS C12orf42	1.29e-04	176	123	5	71b3309ddadd035a1224fca4fc5946dc4c0283fe
ToppCell	Control-B_cells-B_cells\|Control / group, cell type (main and fine annotations)	PIK3AP1 HDAC9 ZNF318 SETBP1 C12orf42	1.29e-04	176	123	5	d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-B_cells-Memory_B\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIK3AP1 DOK3 ESPNL ARHGAP30 TMED8	1.32e-04	177	123	5	0d1c39e99144fdb9c7f6f98a1ade41c73db45b65
ToppCell	facs-Thymus-Epithelium-3m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3AP1 CECR2 TDRD7 TLE1 IRS2	1.32e-04	177	123	5	c2b8a3a149d70f77612759dea34df9e43953c566
ToppCell	facs-Thymus-Epithelium-3m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3AP1 CECR2 TDRD7 TLE1 IRS2	1.32e-04	177	123	5	384f841aa7b2d05815af7885e481f5affc55d897
ToppCell	facs-Thymus-Epithelium-3m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3AP1 CECR2 TDRD7 TLE1 IRS2	1.32e-04	177	123	5	0e9e44119653abfd270e602e5e477a15e774638f
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRRC37A3 DTNA ARHGEF10L NCOR2 PCDH1	1.43e-04	180	123	5	c72f15763ba707189e29c85db533557f01c7fdb1
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CECR2 FMNL3 NCOR2 PRICKLE3 NBEAL2	1.47e-04	181	123	5	f6629fa71bb94405f523f63a9264cacf6d15c5f4
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	HIVEP2 ENOX1 DTNA SETBP1 RERE	1.51e-04	182	123	5	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	COVID-19-Heart-CM_4\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HDAC9 ENOX1 DTNA DGKD DMD	1.54e-04	183	123	5	2902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	HDAC9 NBEAL1 DTNA HIPK2 DMD	1.54e-04	183	123	5	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	NBEAL1 HIPK2 TLE1 SETBP1 NEURL1B	1.58e-04	184	123	5	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	NEDD4L DTNA SEMA6D NBEAL2 DMD	1.58e-04	184	123	5	561592edc3083fad41b91811151b442207c65dd9
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ENOX1 HIPK2 SEMA6D CACNA1G CABIN1	1.63e-04	185	123	5	1ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell	facs-SCAT-Fat-3m-Lymphocytic-B_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3AP1 DOK3 ZNF318 CACNA1I IRS2	1.67e-04	186	123	5	d5d990d8b6ccd8ca8fe7d0d7dedbe2359ae7b582
ToppCell	tumor_Lung-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	ZFAT ERN1 OFD1 SETBP1 ANKRD11	1.67e-04	186	123	5	3d7c1a281fb82db4471283f39937007d889a5f38
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ENOX1 DTNA SEMA6D TLE1 CACNA1G	1.71e-04	187	123	5	5258674d0346e5c51a4b965efcdc1790c970845d
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DTNA HIPK2 SEMA6D DACH2 SETBP1	1.71e-04	187	123	5	13731298bc562ec29582f5da1b4c97261284f6f1
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	DGKD CACNA1I RERE WDFY3 CABIN1	1.71e-04	187	123	5	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	HIVEP2 NEDD4L ERN1 MBNL1 DGKD	1.71e-04	187	123	5	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	HDAC9 NBEAL1 DTNA MBNL1 DMD	1.75e-04	188	123	5	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	343B-Lymphocytic-ILC-ILC-1\|343B / Donor, Lineage, Cell class and subclass (all cells)	PIK3AP1 TBC1D24 MZF1 SETBP1 L3MBTL3	1.75e-04	188	123	5	8f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF318 TLE1 SETBP1 C12orf42 RERE	1.75e-04	188	123	5	d8decd9b5967873ca8320c2f9f07365f163c777f
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DTNA SEMA6D DACH2 KCNH2 DMD	1.75e-04	188	123	5	f54b063025d80de631382bf5326bc40aab7f7d00
ToppCell	LV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	HIVEP2 NCOR2 SH3PXD2B TLE1 CACNA1G	1.80e-04	189	123	5	3922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HDAC9 DGKD ZNF318 TLE1 C12orf42	1.80e-04	189	123	5	e2bb5900d210386b7b74938e7a3636d0c7ba1bcf
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	NEDD4L SEMA6D SETBP1 RERE WDFY3	1.80e-04	189	123	5	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	CTRL-Lymphoid-B_cell\|Lymphoid / Disease state, Lineage and Cell class	PIK3AP1 HDAC9 DOK3 DGKD SETBP1	1.80e-04	189	123	5	14f3a8c0f4f057ad4e6839b4c3eeaf956d6dc92e
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	HIPK2 OAZ2 PGF NEURL1B CABIN1	1.80e-04	189	123	5	f4865b7db16de15120504147a8016ac522ad242a
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FOXK2 DGKD SACS TLE1 RERE	1.84e-04	190	123	5	ed100e271aac82806f59e0c613ccda63f59100c1
ToppCell	Adult-Immune-monocyte-D175\|Adult / Lineage, Cell type, age group and donor	PIK3AP1 HDAC9 ARHGAP30 ZNF710 FMNL3	1.88e-04	191	123	5	cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3AP1 CECR2 DOK3 DGKD TRIM11	1.88e-04	191	123	5	318323a12029a7992f16382cb0c186f5b2e1ca47
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	FOXK2 GBF1 HIPK2 ARHGAP30 TLE1	1.88e-04	191	123	5	2b427741a58921e161101a282d1fe526cd9e760d
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3AP1 CECR2 DOK3 DGKD TRIM11	1.88e-04	191	123	5	4aa29337f4d2528577bb90dc4abfb6eab93e120f
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3AP1 HDAC9 CECR2 DGKD IRS2	1.93e-04	192	123	5	2de242d81dc085ae734eb7d1f091af9a542e0866
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 HDAC9 DTNA ARHGAP30 C12orf42	1.93e-04	192	123	5	86d792682ba51696f503c79625dd20f87bcf651f
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	TNFRSF25 DLG5 HIPK2 TLE1 CRACDL	1.93e-04	192	123	5	e16035b3328f9b1b2e28d234c62ba88387540550
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 HDAC9 DTNA ARHGAP30 C12orf42	1.93e-04	192	123	5	d0ad6a205ad50a3c523fa68676996b289eabc5de
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3AP1 HDAC9 CECR2 DGKD IRS2	1.93e-04	192	123	5	ba2a683472a8b785dbf666dc6e94356d879486c3
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	HDAC9 TLE1 SETBP1 RERE IPMK	1.98e-04	193	123	5	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC9 ARHGAP30 ZNF710 FMNL3 C12orf42	1.98e-04	193	123	5	3e3d7cb3e7242ec9c9677e07e303835649852b52
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D122\|Adult / Lineage, Cell type, age group and donor	PIK3AP1 DOK3 HIPK2 ARHGEF10L SH3PXD2B	1.98e-04	193	123	5	cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCell	URO\|World / Disease, Lineage and Cell Type	PIK3AP1 HIPK2 SH3PXD2B NBEAL2 IRS2	1.98e-04	193	123	5	421dc0996c6c973f88e90197b651255ae4dd13a2
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)\|Adult / Lineage, Cell type, age group and donor	PIK3AP1 HDAC9 ARHGEF10L ZNF710 SH3PXD2B	1.98e-04	193	123	5	31c0978ba78c9516d498aec0798902e57555e557
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 HDAC9 DTNA ARHGAP30 C12orf42	1.98e-04	193	123	5	f597fefc54327a1ad136e2f66b6e81cc5c761eb7
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PIK3AP1 DOK3 TNRC6B ZNF318 SETBP1	2.03e-04	194	123	5	ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell	LV-14._Fibroblast_III\|LV / Chamber and Cluster_Paper	HIVEP2 NCOR2 SH3PXD2B TLE1 CACNA1G	2.03e-04	194	123	5	927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 HDAC9 DTNA ARHGAP30 C12orf42	2.07e-04	195	123	5	91a3c439f10c03c5d51d904f512b6a08040edc76
ToppCell	Biopsy_Control_(H.)-Immune-pDCs\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	HDAC9 ZFAT ERN1 RELB FER1L6	2.07e-04	195	123	5	47d139215f0b51f5ea9b5fb09b1100e320e3f1e2
ToppCell	wk_08-11-Hematologic-Myeloid-Myelocyte-like\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MBNL1 ZBTB4 VPS9D1 ZNF668 RGL4	2.12e-04	196	123	5	4b88c96b737a747422674ad99c073b28e6febc7c
ToppCell	Tracheal-10x5prime-Stromal-Schwann\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DTNA ARHGAP39 SEMA6D TRIM9 DMD	2.12e-04	196	123	5	b6226163d9fc93ecfff2115bb74408303a000490
ToppCell	facs-Brain_Non-Myeloid-Cortex\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DTNA HIPK2 SEMA6D TRIM9 IRS2	2.12e-04	196	123	5	256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_cell-B_naive\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HDAC9 FOXN4 ESPNL SETBP1 C12orf42	2.12e-04	196	123	5	de43dd0697e1daf4d50800957cf0b27b54a7a333
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PIK3AP1 HDAC9 ESPNL SETBP1 C12orf42	2.18e-04	197	123	5	da61afba697ec49ca86e062d35a825280da558ac
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VGLL3 NBEAL1 PGF RTL1 PEAK1	2.18e-04	197	123	5	2872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DTNA ARHGEF10L SETBP1 NEURL1B DMD	2.23e-04	198	123	5	bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4\|GI_small-bowel / Manually curated celltypes from each tissue	TNFRSF25 HIVEP2 ERN1 RELB IRS2	2.23e-04	198	123	5	6333e46cd1ccf5841ce15aea98a4b2f5e3ae4675
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Trm_Th1/Th17\|GI_small-bowel / Manually curated celltypes from each tissue	TNFRSF25 HIVEP2 ERN1 RELB IRS2	2.28e-04	199	123	5	508a6efc11b1b45899a968888865731088cac668
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	LRRC37A3 TNRC6B RERE WDFY3 DMD	2.28e-04	199	123	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DTNA ARHGEF10L SETBP1 NEURL1B DMD	2.28e-04	199	123	5	b1753474152b82a0b811b9878c890a359e14919a
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Intermediate\|10w / Sample Type, Dataset, Time_group, and Cell type.	ZBTB9 HIPK2 SEMA6D CRACDL TMED8	2.33e-04	200	123	5	e5a8647c47a49c8c90c78d681193946de103d8ff
Computational	Neighborhood of MAP4K4	DTNA HIPK2 OAZ2 SH2B1 ZNF710 PEAK1 CLEC16A	6.19e-05	172	63	7	GCM_MAP4K4
Drug	Foliosidine [2520-38-9]; Down 200; 13uM; PC3; HT_HG-U133A	TNFRSF25 GBF1 NEDD4L DTNA RBM42 RELB ZNF668 YLPM1 PCDH1 CLEC16A	1.20e-07	197	123	10	4295_DN
Drug	Dipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A	TNFRSF25 SPHK2 HIVEP2 DTNA HIPK2 SH2B1 SEMA6D IRS2 CABIN1	1.03e-06	192	123	9	3929_DN
Drug	Domperidone maleate; Down 200; 7.4uM; PC3; HT_HG-U133A	TNFRSF25 DLG5 ELOA2 FRMPD1 HIPK2 GON4L PRICKLE3 MZF1 CACNA1I	1.27e-06	197	123	9	4640_DN
Drug	S(-)-terguride hydrogen maleate [37686-85-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A	DTNA HIPK2 RELB SH2B1 TDRD7 PRICKLE3 KCNH2 CACNA1I CLEC16A	1.33e-06	198	123	9	6473_DN
Drug	Dimethisoquin hydrochloride [2773-92-4]; Down 200; 13uM; MCF7; HT_HG-U133A	DLG5 GBF1 DTNA GON4L TNRC6B ZNF318 SH2B1 ZNF710 PRICKLE3	1.33e-06	198	123	9	4791_DN
Drug	6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine	PTPN23 PGF PRR12 SH3PXD2B RTL1 RERE NOTCH1	1.56e-06	104	123	7	ctd:C000595015
Drug	Ethambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; PC3; HT_HG-U133A	TNFRSF25 GBF1 DTNA SH2B1 MZF1 RERE CABIN1 INO80B	1.07e-05	194	123	8	4001_DN
Drug	Oxprenolol hydrochloride [6452-73-9]; Down 200; 13.2uM; MCF7; HT_HG-U133A	NEDD4L DTNA GON4L ZNF318 SH2B1 ZNF710 ZNF668 NBEAL2	1.16e-05	196	123	8	3568_DN
Drug	(+/-)-blebbistatin; Down 200; 17uM; MCF7; HT_HG-U133A_EA	MBNL1 TNRC6B ZNF710 ZNF668 PRICKLE3 MZF1 ZNF580 INO80B	1.16e-05	196	123	8	837_DN
Drug	Deptropine citrate [2169-75-7]; Up 200; 7.6uM; HL60; HT_HG-U133A	SPHK2 RBM42 C11orf16 ZNF710 NCOR2 YLPM1 CACNA1I ZNF580	1.16e-05	196	123	8	3144_UP
Drug	Alcuronium chloride [15180-03-7]; Up 200; 5.4uM; MCF7; HT_HG-U133A	HDAC9 TNFRSF25 ERN1 GIT1 ZNF710 NCOR2 TLE1 IRS2	1.16e-05	196	123	8	7345_UP
Drug	Thioperamide maleate [106243-16-7]; Down 200; 9.8uM; PC3; HT_HG-U133A	TNFRSF25 DTNA FRMPD1 SH2B1 TLE1 CACNA1G IRS2 RERE	1.16e-05	196	123	8	4675_DN
Drug	Etofylline [519-37-9]; Up 200; 17.8uM; MCF7; HT_HG-U133A	ELOA2 GIT1 ZNF318 VPS9D1 MZF1 KCNH2 NBEAL2 PCDH1	1.20e-05	197	123	8	5467_UP
Drug	Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A	TNFRSF25 SPHK2 VGLL3 DOK3 FRMPD1 KCNH2 SETBP1 PCDH1	1.20e-05	197	123	8	5641_UP
Drug	U-62066 [87151-85-7]; Down 200; 1uM; PC3; HT_HG-U133A	TNFRSF25 FOXK2 GON4L RELB TESK1 PRICKLE3 RERE CABIN1	1.20e-05	197	123	8	4553_DN
Drug	Chlorzoxazone [95-25-0]; Down 200; 23.6uM; PC3; HT_HG-U133A	GBF1 HIPK2 DGKD ZNF318 SH2B1 CTDP1 CALML4 CABIN1	1.24e-05	198	123	8	2100_DN
Drug	Harmol hydrochloride monohydrate [40580-83-4]; Up 200; 15.8uM; PC3; HT_HG-U133A	HDAC9 ELOA2 RELB CTDP1 CALML4 CABIN1 JPT2 INO80B	1.24e-05	198	123	8	7320_UP
Drug	Tribenoside [10310-32-4]; Up 200; 8.4uM; PC3; HT_HG-U133A	TNFRSF25 ELOA2 DTNA FRMPD1 RELB NBEAL2 CACNA1G INO80B	1.24e-05	198	123	8	6328_UP
Drug	Dimaprit dihydrochloride [23256-33-9]; Up 200; 17uM; MCF7; HT_HG-U133A	TNFRSF25 DLG5 HIVEP2 DTNA TNRC6B ZNF318 ZNF710 SEMA6D	1.24e-05	198	123	8	6520_UP
Drug	arachidonic acid sodium salt; Up 200; 10uM; MCF7; HG-U133A	TNFRSF25 DTNA RELB TLE1 YLPM1 CTDP1 CACNA1I RERE	1.24e-05	198	123	8	443_UP
Drug	Sulfabenzamide [127-71-9]; Down 200; 14.4uM; PC3; HT_HG-U133A	TNFRSF25 GON4L SH2B1 NCOR2 PRICKLE3 MZF1 IRS2 INO80B	1.29e-05	199	123	8	6634_DN
Drug	themisone	CACNA1I CACNA1G DMD	3.27e-05	12	123	3	CID000016235
Drug	fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA	HIVEP2 DTNA PRICKLE3 MZF1 TLE1 IRS2 ZNF580	4.23e-05	172	123	7	1017_UP
Drug	Mibefradil	KCNH2 CACNA1I CACNA1G	4.23e-05	13	123	3	ctd:D020748
Drug	17-AAG; Down 200; 1uM; PC3; HT_HG-U133A	HDAC9 TNFRSF25 SF3A1 TNRC6B TDRD7 SETBP1 XPNPEP3	7.67e-05	189	123	7	1206_DN
Drug	Verapamil	KCNH2 CACNA1I CACNA1G	8.18e-05	16	123	3	DB00661
Drug	Lanatoside C [17575-22-3]; Down 200; 4uM; PC3; HT_HG-U133A	TNFRSF25 SPHK2 ZNF710 PRICKLE3 CABIN1 PCDH1 INO80B	8.19e-05	191	123	7	4328_DN
Drug	NSC759576	HIVEP2 DGKD RELB SACS KCNH2 CACNA1I CACNA1G	8.19e-05	191	123	7	CID000003075
Drug	thioridazine hydrochloride; Down 200; 10uM; PC3; HT_HG-U133A	DLG5 VGLL3 GIT1 ZNF668 TRIM9 TLE1 MCM3AP	8.19e-05	191	123	7	4454_DN
Drug	Metergoline [17692-51-2]; Up 200; 10uM; MCF7; HT_HG-U133A	GBF1 DTNA ZNF710 VPS9D1 MZF1 CTDP1 IRS2	8.19e-05	191	123	7	5344_UP
Drug	1,3-dioxoisoindoline-5-carboxamide	CACNA1I CACNA1G	8.65e-05	3	123	2	CID010679219
Drug	Cimetidine [51481-61-9]; Down 200; 15.8uM; MCF7; HT_HG-U133A	ERN1 VPS9D1 CTDP1 IRS2 RERE NOTCH1 INO80B	8.75e-05	193	123	7	1464_DN
Drug	Mebeverine hydrochloride [2753-45-9]; Up 200; 8.6uM; PC3; HT_HG-U133A	TNFRSF25 DLG5 ZNF318 MZF1 CALML4 RERE CABIN1	8.75e-05	193	123	7	7147_UP
Drug	Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A	TNFRSF25 SPHK2 DGKD CTDP1 CALML4 RERE INO80B	8.75e-05	193	123	7	3262_UP
Drug	ICI 182,780; Up 200; 0.01uM; MCF7; HT_HG-U133A	TNFRSF25 DLG5 SH2B1 VPS9D1 PRICKLE3 TLE1 XPNPEP3	8.75e-05	193	123	7	6997_UP
Drug	Graveoline [485-61-0]; Down 200; 14.4uM; MCF7; HT_HG-U133A	DLG5 HIVEP2 DTX3 SH2B1 ZNF710 PRICKLE3 WDFY3	8.75e-05	193	123	7	3614_DN
Drug	Trazodone hydrochloride [25332-39-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A	TNFRSF25 DLG5 SPHK2 GBF1 ERN1 TLE1 IRS2	9.03e-05	194	123	7	7410_UP
Drug	Butoconazole nitrate [32872-77-1]; Down 200; 8.4uM; HL60; HT_HG-U133A	DLG5 DTNA TNRC6B TESK1 PIAS3 MZF1 INO80B	9.03e-05	194	123	7	2427_DN
Drug	Neomycin sulfate [1405-10-3]; Down 200; 4.2uM; MCF7; HT_HG-U133A	HIVEP2 DTNA ZNF318 TESK1 ZNF668 MZF1 CABIN1	9.03e-05	194	123	7	7221_DN
Drug	radicicol; Down 200; 0.1uM; PC3; HT_HG-U133A	TNFRSF25 DLG5 SH2B1 NCOR2 SEMA6D RERE PCDH1	9.03e-05	194	123	7	5952_DN
Drug	Pentoxifylline [6493-05-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A	TNFRSF25 SEMA6D CACNA1I CACNA1G RERE SLC14A2 INO80B	9.33e-05	195	123	7	2290_UP
Drug	Naringenine [480-41-1]; Down 200; 14.6uM; PC3; HT_HG-U133A	TNFRSF25 GIT1 HIPK2 GON4L ZNF318 SETBP1 IRS2	9.33e-05	195	123	7	4597_DN
Drug	Leflunomide [75706-12-6]; Up 200; 14.8uM; PC3; HT_HG-U133A	TNFRSF25 ENOX1 RELB ZNF710 CACNA1G CABIN1 INO80B	9.33e-05	195	123	7	5884_UP
Drug	Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; MCF7; HT_HG-U133A	SPHK2 DTX3 HIPK2 KCNH2 MCM3AP CACNA1I IRS2	9.33e-05	195	123	7	5665_UP
Drug	Sulfamerazine [127-79-7]; Down 200; 15.2uM; PC3; HT_HG-U133A	TNFRSF25 DTNA RELB NCOR2 TRIM9 MCM3AP PCDH1	9.33e-05	195	123	7	3718_DN
Drug	Boldine [476-70-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A	TNFRSF25 DLG5 ELOA2 RELB SH2B1 RERE NOTCH1	9.63e-05	196	123	7	4122_DN
Drug	Quinethazone [73-49-4]; Up 200; 13.8uM; PC3; HT_HG-U133A	TNFRSF25 SPHK2 DTNA C11orf16 VPS9D1 CACNA1I RERE	9.63e-05	196	123	7	3793_UP
Drug	Aminocaproic acid [60-32-2]; Up 200; 30.4uM; MCF7; HT_HG-U133A	TNFRSF25 ELOA2 RELB ZNF318 TLE1 CABIN1 INO80B	9.63e-05	196	123	7	6501_UP
Drug	Hydrochlorothiazide [58-93-5]; Down 200; 13.4uM; MCF7; HT_HG-U133A	GBF1 ERN1 ZNF318 XPNPEP3 YLPM1 CABIN1 INO80B	9.63e-05	196	123	7	1487_DN
Drug	Piretanide [55837-27-9]; Down 200; 11uM; MCF7; HT_HG-U133A	NEDD4L ERN1 GON4L KCNH2 YLPM1 CTDP1 INO80B	9.63e-05	196	123	7	3567_DN
Drug	Thiamphenicol [15318-45-3]; Up 200; 11.2uM; HL60; HT_HG-U133A	SPHK2 GIT1 DTNA SF3A1 DOK3 C11orf16 ZNF668	9.63e-05	196	123	7	1867_UP
Drug	Benfotiamine [22457-89-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A	TNFRSF25 SPHK2 NCOR2 KCNH2 MCM3AP RERE WDFY3	9.63e-05	196	123	7	3837_UP
Drug	1-phenylbiguanide hydrochloride; Up 200; 10uM; MCF7; HG-U133A	TNFRSF25 DGKD ZNF318 ZNF710 YLPM1 CABIN1 PCDH1	9.94e-05	197	123	7	22_UP
Drug	3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A	NEDD4L HIPK2 GON4L SEMA6D KCNH2 CTDP1 CACNA1I	9.94e-05	197	123	7	6060_DN
Drug	Diloxanide furoate [3736-81-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A	TNRC6B PGF ZNF710 TLE1 XPNPEP3 IRS2 CABIN1	9.94e-05	197	123	7	5025_DN
Drug	Xamoterol hemifumarate [73210-73-8]; Down 200; 5uM; MCF7; HT_HG-U133A	ELOA2 HIVEP2 ERN1 SH2B1 NCOR2 RERE WDFY3	9.94e-05	197	123	7	3401_DN
Drug	Alfaxalone [23930-19-0]; Up 200; 12uM; MCF7; HT_HG-U133A	DLG5 DTNA RELB ZNF318 NCOR2 KCNH2 CTDP1	9.94e-05	197	123	7	6514_UP
Drug	Glipizide [29094-61-9]; Down 200; 9uM; MCF7; HT_HG-U133A	SPHK2 HIVEP2 DTNA GON4L SH2B1 CTDP1 IRS2	9.94e-05	197	123	7	1508_DN
Drug	Moxonidine [75438-57-2]; Up 200; 16.6uM; MCF7; HT_HG-U133A	TNFRSF25 ERN1 DTNA ZNF710 VPS9D1 PRICKLE3 TLE1	9.94e-05	197	123	7	7343_UP
Drug	Pirenperone [ 75444-65-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A	RELB C11orf16 SEMA6D SETBP1 IRS2 RERE PEAK1	9.94e-05	197	123	7	5274_UP
Drug	Oxyphenbutazone [129-20-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A	NEDD4L ERN1 TNRC6B SH2B1 KCNH2 YLPM1 CTDP1	9.94e-05	197	123	7	3582_DN
Drug	Alprostadil [745-65-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A	GBF1 TNRC6B RELB ZNF318 MZF1 KCNH2 CABIN1	9.94e-05	197	123	7	7358_DN
Drug	Hydroflumethiazide [135-09-1]; Down 200; 12uM; PC3; HT_HG-U133A	GBF1 GIT1 SF3A1 RBM42 ZNF318 ZNF580 NOTCH1	9.94e-05	197	123	7	1809_DN
Drug	Procaine hydrochloride [51-05-8]; Up 200; 14.6uM; PC3; HT_HG-U133A	TNFRSF25 SPHK2 TRIM9 NBEAL2 RERE PCDH1 INO80B	9.94e-05	197	123	7	1796_UP
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A	TNFRSF25 NEDD4L SF3A1 HIPK2 VPS9D1 NCOR2 CACNA1I	9.94e-05	197	123	7	5207_UP
Drug	Methyldopate hydrochloride [2508-79-4]; Down 200; 14.6uM; MCF7; HT_HG-U133A	ELOA2 DTNA VPS9D1 ZNF668 YLPM1 CTDP1 RERE	9.94e-05	197	123	7	4986_DN
Drug	Baclofen (R,S) [1134-47-0]; Down 200; 18.8uM; PC3; HT_HG-U133A	DLG5 ZNF318 MZF1 MTRR CALML4 WDFY3 NOTCH1	9.94e-05	197	123	7	6313_DN
Drug	Cefixime [79350-37-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A	DTNA SF3A1 HIPK2 DGKD ZNF318 VPS9D1 IRS2	9.94e-05	197	123	7	3247_UP
Drug	Dipyrone [5907-38-0]; Down 200; 12uM; PC3; HT_HG-U133A	TNFRSF25 SPHK2 HIVEP2 RELB ARHGEF10L MZF1 MCM3AP	1.03e-04	198	123	7	3754_DN
Drug	Xylometazoline hydrochloride [1218-35-5]; Up 200; 14.2uM; PC3; HT_HG-U133A	GIT1 DTNA ZNF668 TRIM9 CABIN1 PCDH1 NOTCH1	1.03e-04	198	123	7	2107_UP
Drug	(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; PC3; HT_HG-U133A	GBF1 GIT1 DTNA GON4L RELB CTDP1 NOTCH1	1.03e-04	198	123	7	4546_DN
Drug	Roxarsone [121-19-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A	SPHK2 FRMPD1 ZNF318 PRICKLE3 MZF1 IRS2 WDFY3	1.03e-04	198	123	7	5470_UP
Drug	(S)-propranolol hydrochloride [4199-10-4]; Down 200; 13.6uM; PC3; HT_HG-U133A	HDAC9 TNFRSF25 HIVEP2 TNRC6B MZF1 CABIN1 NOTCH1	1.03e-04	198	123	7	6343_DN
Drug	SR-95639A [115767-94-7]; Up 200; 10uM; MCF7; HT_HG-U133A	DLG5 NEDD4L HIPK2 CACNA1I RERE CABIN1 PCDH1	1.03e-04	198	123	7	4977_UP
Drug	Mebendazole [31431-39-7]; Down 200; 13.6uM; PC3; HT_HG-U133A	HIPK2 ZNF318 TLE1 NBEAL2 SETBP1 XPNPEP3 WDFY3	1.03e-04	198	123	7	7370_DN
Drug	Trapidil [15421-84-8]; Up 200; 19.4uM; MCF7; HT_HG-U133A	DLG5 SPHK2 ERN1 DTNA HIPK2 SETBP1 RERE	1.03e-04	198	123	7	7475_UP
Drug	Atropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	TNFRSF25 ERN1 TNRC6B VPS9D1 SEMA6D PCDH1 INO80B	1.03e-04	198	123	7	2216_UP
Drug	Karakoline [39089-30-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A	TNFRSF25 SPHK2 NEDD4L C11orf16 NCOR2 RERE INO80B	1.03e-04	198	123	7	3638_UP
Drug	cis-4,7,10,13,16,19-Docosahexaenoic acid ethyl ester; Down 200; 100uM; PC3; HG-U133A	TNFRSF25 NEDD4L HIPK2 SH2B1 MZF1 KCNH2 JPT2	1.03e-04	198	123	7	664_DN
Drug	Pepstatin A [26305-03-3]; Up 200; 5.8uM; MCF7; HT_HG-U133A	TNFRSF25 ELOA2 HIVEP2 ERN1 FRMPD1 KCNH2 CACNA1G	1.03e-04	198	123	7	4790_UP
Drug	(S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; HL60; HT_HG-U133A	GIT1 FRMPD1 C11orf16 ZNF710 ZNF668 CACNA1I INO80B	1.03e-04	198	123	7	3067_UP
Drug	Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; PC3; HT_HG-U133A	TNFRSF25 DLG5 HIVEP2 MZF1 YLPM1 ZNF580 NOTCH1	1.03e-04	198	123	7	2074_DN
Drug	Ethynodiol diacetate [297-76-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A	TNFRSF25 SPHK2 DTNA HIPK2 ZNF710 PRICKLE3 INO80B	1.03e-04	198	123	7	6479_DN
Drug	Butirosin disulfate salt [51022-98-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A	ERN1 ZNF710 TDRD7 SEMA6D CTDP1 IRS2 PCDH1	1.03e-04	198	123	7	6080_DN
Drug	Azapropazone [13539-59-8]; Up 200; 13.4uM; MCF7; HT_HG-U133A	NEDD4L DTNA RELB CTDP1 RERE PCDH1 INO80B	1.03e-04	198	123	7	6522_UP
Drug	9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A	TNFRSF25 ELOA2 DTNA HIPK2 ZNF710 VPS9D1 NCOR2	1.06e-04	199	123	7	7552_DN
Drug	Baclofen (R,S) [1134-47-0]; Down 200; 18.8uM; MCF7; HT_HG-U133A	SPHK2 HIVEP2 DTNA TNRC6B SH2B1 CTDP1 INO80B	1.06e-04	199	123	7	1536_DN
Drug	Isradipine [75695-93-1]; Up 200; 10.8uM; HL60; HT_HG-U133A	ELOA2 ERN1 DOK3 C11orf16 TESK1 YLPM1 INO80B	1.06e-04	199	123	7	3129_UP
Drug	Glutethimide, para-amino [125-84-8]; Down 200; 17.2uM; MCF7; HT_HG-U133A	TNRC6B ZNF318 TESK1 ZNF710 ZNF668 CLEC16A NOTCH1	1.06e-04	199	123	7	7421_DN
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; PC3; HT_HG-U133A	SPHK2 DTNA ZNF710 CTDP1 IRS2 CABIN1 INO80B	1.06e-04	199	123	7	4297_DN
Drug	Isometheptene mucate; Up 200; 8.2uM; MCF7; HT_HG-U133A	DTNA RELB ZNF710 KCNH2 CTDP1 RERE CABIN1	1.06e-04	199	123	7	6524_UP
Drug	Methoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; PC3; HT_HG-U133A	DTNA TESK1 ZNF710 NCOR2 PRICKLE3 CACNA1G INO80B	1.06e-04	199	123	7	6355_UP
Drug	Tetracaone hydrochloride [136-47-0]; Down 200; 13.2uM; HL60; HG-U133A	FOXK2 HIPK2 ABT1 MZF1 TRIM9 MTRR IRS2	1.06e-04	199	123	7	1739_DN
Drug	Prenylamine lactate [69-43-2]; Down 200; 9.6uM; HL60; HG-U133A	TNFRSF25 HIPK2 TNRC6B MZF1 TRIM9 YLPM1 MTRR	1.06e-04	199	123	7	1737_DN
Drug	Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; PC3; HT_HG-U133A	GBF1 ZNF318 ZNF710 MZF1 SETBP1 YLPM1 WDFY3	1.06e-04	199	123	7	6308_DN
Drug	Methyldopa (L,-) [555-30-6]; Down 200; 19uM; MCF7; HT_HG-U133A	ELOA2 DTNA ZNF710 MZF1 CACNA1I IRS2 CABIN1	1.06e-04	199	123	7	5637_DN
Drug	Meptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A	NEDD4L FRMPD1 NCOR2 SETBP1 CACNA1I RERE CABIN1	1.06e-04	199	123	7	4774_UP
Drug	U-62066 [87151-85-7]; Down 200; 1uM; MCF7; HT_HG-U133A	TNFRSF25 C11orf16 NCOR2 SETBP1 CACNA1I IRS2 INO80B	1.06e-04	199	123	7	4375_DN
Drug	Khellin [82-02-0]; Up 200; 15.4uM; MCF7; HT_HG-U133A	DTNA FRMPD1 KCNH2 MCM3AP CACNA1I IRS2 WDFY3	1.09e-04	200	123	7	1504_UP
Drug	Noscapine [128-62-1]; Up 200; 9.6uM; PC3; HT_HG-U133A	VGLL3 DOK3 ZNF668 PRICKLE3 CTDP1 CACNA1I INO80B	1.09e-04	200	123	7	5851_UP
Disease	lymphocyte percentage of leukocytes	PIK3AP1 HDAC9 SPHK2 GBF1 ERN1 CECR2 MBNL1 ZNF710 CPSF4 RERE NEURL1B	7.02e-05	665	117	11	EFO_0007993
Disease	eosinophil count	ZFAT HIVEP2 SF3A1 ZBTB9 ZC3HC1 NCOR2 SH3PXD2B TMED8 SEC16A ANKRD11 CALML4 RERE PEAK1 NEURL1B CLEC16A NOTCH1	2.64e-04	1488	117	16	EFO_0004842
Disease	comparative body size at age 10, self-reported	LRRC37A2 TNRC6B SH2B1 ZNF710 FAM120A SEMA6D C12orf42 RERE	2.78e-04	420	117	8	EFO_0009819
Disease	waist-hip ratio	VGLL3 ZFAT FOXK2 TNRC6B ZNF318 SH2B1 TDRD7 SH3PXD2B SETBP1 RERE NEURL1B L3MBTL3 CLEC16A SLC14A2	3.62e-04	1226	117	14	EFO_0004343
Disease	Craniofacial Abnormalities	FAM83H SH3PXD2B SETBP1 MNT NOTCH1	4.03e-04	156	117	5	C0376634
Disease	body weight	ZFAT HIVEP2 NBEAL1 MBNL1 GON4L TNRC6B SH2B1 SH3PXD2B SEMA6D DACH2 KCNH2 SETBP1 DMD L3MBTL3	4.79e-04	1261	117	14	EFO_0004338
Disease	Neurodevelopmental Disorders	TNRC6B SETBP1 ANKRD11 WDFY3	5.22e-04	93	117	4	C1535926
Disease	lymphocyte count	PIK3AP1 HDAC9 SPHK2 ZFAT GBF1 MBNL1 TNRC6B DGKD ZNF710 MCM3AP ANKRD11 RERE NEURL1B L3MBTL3 CLEC16A	6.86e-04	1464	117	15	EFO_0004587
Disease	body surface area	ZFAT MBNL1 ZBTB4 ZBTB9 NCOR2 KCNH2 ANKRD11 C12orf42 L3MBTL3	1.07e-03	643	117	9	EFO_0022196
Disease	Malignant neoplasm of breast	DTX3 FRMPD1 LRRC37A2 ZNF318 TESK1 ZNF668 LRRC37A PRICKLE3 SETBP1 DMD L3MBTL3 NOTCH1	1.17e-03	1074	117	12	C0006142
Disease	balding measurement	HDAC9 DLG5 MBNL1 VPS9D1 NCOR2 SH3PXD2B SETBP1 RERE L3MBTL3 SLC14A2	1.24e-03	792	117	10	EFO_0007825
Disease	gamma-glutamylglutamate measurement	ZNF318 IPMK	1.38e-03	14	117	2	EFO_0021137
Disease	mean corpuscular hemoglobin concentration	HDAC9 ZFAT FOXK2 LRRC37A2 GON4L TNRC6B ZNF318 SH2B1 SEC16A CACNA1I IRS2 NEURL1B	1.48e-03	1105	117	12	EFO_0004528
Disease	sexual dimorphism measurement	ZFAT HIVEP2 ZBTB4 PTPN23 ABT1 RELB ZNF710 NCOR2 KCNH2 SEC16A ANKRD11 L3MBTL3	1.50e-03	1106	117	12	EFO_0021796
Disease	insomnia measurement	HDAC9 NEDD4L ZBTB9 ARHGEF10L ZNF580 PCDH1 MNT	1.97e-03	443	117	7	EFO_0007876
Disease	coronary artery disease, plasminogen activator inhibitor 1 measurement	HDAC9 NBEAL1 ZC3HC1	2.03e-03	63	117	3	EFO_0001645, EFO_0004792
Disease	Familial Progressive Myoclonic Epilepsy	TBC1D24 SACS	2.04e-03	17	117	2	C0751777
Disease	Atypical Inclusion-Body Disease	TBC1D24 SACS	2.04e-03	17	117	2	C0751776
Disease	Myoclonic Epilepsies, Progressive	TBC1D24 SACS	2.04e-03	17	117	2	C0751778
Disease	response to cyclophosphamide	HIPK2 TRIM9	2.04e-03	17	117	2	GO_1902518
Disease	Biotin-Responsive Encephalopathy	TBC1D24 SACS	2.04e-03	17	117	2	C0751780
Disease	May-White Syndrome	TBC1D24 SACS	2.04e-03	17	117	2	C0751782
Disease	Dentatorubral-Pallidoluysian Atrophy	TBC1D24 SACS	2.04e-03	17	117	2	C0751781
Disease	Intellectual Disability	HIVEP2 GON4L PTPN23 PRR12 SACS SETBP1 CACNA1G	2.08e-03	447	117	7	C3714756
Disease	biological sex	ARHGAP39 SEMA6D SETBP1 PEAK1 SLC14A2	2.28e-03	230	117	5	PATO_0000047
Disease	Carcinoma of bladder	PEAK1 NOTCH1	2.29e-03	18	117	2	C0699885
Disease	Tourette syndrome, schizophrenia	CACNA1I RERE	2.29e-03	18	117	2	EFO_0004895, MONDO_0005090
Disease	Action Myoclonus-Renal Failure Syndrome	TBC1D24 SACS	2.29e-03	18	117	2	C0751779
Disease	hematocrit	HIVEP2 NBEAL1 MBNL1 TNRC6B ZC3HC1 DGKD PRR12 NCOR2 IRS2 L3MBTL3 SLC14A2	2.31e-03	1011	117	11	EFO_0004348
Disease	monocyte percentage of leukocytes	PIK3AP1 CECR2 ARHGAP30 MCM3AP CTDP1 SEC16A RERE WDFY3 IPMK	2.57e-03	731	117	9	EFO_0007989
Disease	susceptibility to mononucleosis measurement	HDAC9 ZBTB9 DMD	2.63e-03	69	117	3	EFO_0008403
Disease	tissue plasminogen activator measurement, coronary artery disease	HDAC9 NBEAL1 ZC3HC1	2.85e-03	71	117	3	EFO_0001645, EFO_0004791
Disease	social deprivation, COVID-19	CECR2 PGF	3.12e-03	21	117	2	EFO_0009696, MONDO_0100096
Disease	disease	SETBP1 SLC14A2	3.12e-03	21	117	2	EFO_0000408
Disease	sleep duration	HDAC9 GBF1 ZBTB9 ARHGAP30 PRR12 SEMA6D	3.27e-03	362	117	6	EFO_0005271
Disease	serum gamma-glutamyl transferase measurement	PIK3AP1 DLG5 NEDD4L GON4L NCOR2 SH3PXD2B SEMA6D NBEAL2 CABIN1 L3MBTL3	3.50e-03	914	117	10	EFO_0004532
Disease	vital capacity	HDAC9 ZFAT HIVEP2 MBNL1 ZBTB4 FRMPD1 ABT1 SH2B1 NCOR2 NEURL1B L3MBTL3 SLC14A2	3.72e-03	1236	117	12	EFO_0004312
Disease	age of onset of asthma	HDAC9 RERE CLEC16A	3.86e-03	79	117	3	OBA_2001001

Protein segments in the cluster

Peptide	Gene	Start	Entry
DREGVPPTALFHPMP	CTDP1	746	Q9Y5B0
AHLPGPLLSMREPAP	ARHGEF10L	1181	Q9HCE6
MPPHPLPLAEGMDRD	C8orf74	146	Q6P047
AGPHMKEVLPASPRP	ANKRD11	1681	Q6UB99
MAAEHLLPGPPPSLA	CALML4	1	Q96GE6
GMDLSLAPPPRERPA	BHLHE22	41	Q8NFJ8
PPLPSERAEHTPMAP	GIT1	481	Q9Y2X7
HEHKGLSPLPSPPEM	DMD	3531	P11532
DGTPTMSLERPPRVP	PIK3AP1	766	Q6ZUJ8
HPLLPVSLPPASVAM	DACH2	321	Q96NX9
LPPELSHLDPNSPMR	CECR2	411	Q9BXF3
PTRVDDMPPGISLLP	NBEAL1	46	Q6ZS30
PPLGSMAALRPPLEE	RBM42	216	Q9BTD8
MEGPELRHSQPPTPL	ARHGAP39	451	Q9C0H5
MLDLLPPAPPHASAV	RELB	501	Q01201
CPDRMPLPSPTESRH	OFD1	766	O75665
PPEELRSLPPDMVAG	PTPN23	741	Q9H3S7
RSLPPDMVAGPRLPD	PTPN23	746	Q9H3S7
SPPGLPREALEPMLT	KIAA1549	181	Q9HCM3
TGHPLQPPLSPLELM	L3MBTL3	536	Q96JM7
PVSPPEGMTEPGHSR	NCOR2	2221	Q9Y618
VRPGHPCVPSRPDVM	OAZ2	161	O95190
SPTRTAPLRMPEGPE	ELOA2	171	Q8IYF1
PGHPDQPLPREQMTS	ESPNL	376	Q6ZVH7
LMTTAPPPGHPEVTL	LRRC37A3	686	O60309
SPSVPLNHLPGMPDT	NOTCH1	2226	P46531
VSMGPRVLPSPTIHP	HIPK2	1146	Q9H2X6
PPGDMAHARVSEPRP	KIAA1671	636	Q9BY89
LMTTAPPPGHPEVTL	LRRC37A2	686	A6NM11
LMTTAPPPGHPEVTL	LRRC37A	686	A6NMS7
IPDTMAHLISPLPSP	FOXK2	186	Q01167
EHQLPMPPPGVRLDS	KCNQ1DN	11	Q9H478
TRHRMLGPESVPPPK	MYG1	21	Q9HB07
PMPTVDSHEPRLGPR	JPT2	156	Q9H910
HLPDDPSIPIIMVGP	MTRR	531	Q9UBK8
PSPVHGAGPSVMEIP	MCM3AP	1726	O60318
MRAGVLPPPPRHAST	KCNH2	291	Q12809
LMSDAPGDSPRIHLP	PCDH1	941	Q08174
DGTVIHMLPPPPVQR	PEAK1	956	Q9H792
DPGEPMHASPPRKAR	DLG5	1056	Q8TDM6
HTLPVEEPRMEAPPL	MNT	51	Q99583
LPSLDTPGELREMPP	DOK3	331	Q7L591
GPEPPTSRKMHLAEP	DOK3	346	Q7L591
PTRNHMDITTPPLPP	FAM120A	536	Q9NZB2
PRSPPEMSLLHDVGP	CRACDL	161	Q6NV74
MATEPPSPLRVEAPG	IPMK	1	Q8NFU5
VEAPGPPEMRTSPAI	IPMK	11	Q8NFU5
IPEGPRSPSPLMVVD	INO80B	91	Q9C086
HSMPELGLRSVPEPP	PRICKLE3	436	O43900
EGLPSLPSMHEYPLP	IRS2	896	Q9Y4H2
PAPRPGQHALTMPAL	RGL4	126	Q8IZJ4
EMHRAGPPPLRAAPL	DTX3	116	Q8N9I9
APPPSESMEGPSLVR	ABT1	256	Q9ULW3
PPRPHRPEATPSMAS	CABIN1	1996	Q9Y6J0
HVSPRAPLAPLASMP	C5orf60	161	A6NFR6
MQPHPTELPGPDLLT	CACNA1G	2021	O43497
PAHAPARPEAPVDSM	ERN1	426	O75460
RDLEAHPMAPLTSPP	FRMPD1	1356	Q5SYB0
EGMPPSDLDLLAPAP	FMNL3	496	Q8IVF7
IPMTPNGHLDPSLPL	CACNA1I	906	Q9P0X4
IRHISAEVVPMGPPP	GON4L	436	Q3T8J9
LPPVPMVHGATPATV	MBNL1	336	Q9NR56
PRPPSCSLHPEMLSE	DGKD	961	Q16760
SSREPLHPMFPDQPE	DTNA	311	Q9Y4J8
PPRHMTKVTPGSELP	GBF1	236	Q92538
HPRFELPMGTTEQPP	CPSF4	166	O95639
SVLPHPAMDRPLQPG	HDAC9	616	Q9UKV0
REEPPRMPGGALEPH	FAM83H	356	Q6ZRV2
PMLHTESALPPDGRP	ENPP7	411	Q6UWV6
PPRHTPDQSPGMESR	GPRIN1	56	Q7Z2K8
LELPMPGTPIPAEIH	SACS	4151	Q9NZJ4
EEDRLRPPSPPAIMH	ENOX1	246	Q8TC92
RASGSPEDLMPRPLP	ARHGAP30	236	Q7Z6I6
ALPDLSPSPLPHPAM	FOXN4	386	Q96NZ1
PDSSPMLEPEHTPVA	FER1L6	1161	Q2WGJ9
RPPPPCIALERHGMS	RTL1	536	A6NKG5
HFDSMELLPPELPPR	SH2B1	461	Q9NRF2
TLPPGMAAVTVVPPH	SSPOP	2356	A2VEC9
TPCMSPLPHDSPLIE	NBR1	586	Q14596
LHPMDTAPTPAPTRP	NBEAL2	611	Q6ZNJ1
GSVPEPAMPHPLELS	SCP2D1	26	Q9UJQ7
RDLPGAIPPPMSAAH	RERE	1501	Q9P2R6
LPPPVHLSKPGEHMD	TDRD7	901	Q8NHU6
PRLRPEESLDPPGAM	PRR12	866	Q9ULL5
GSVIAPMPPIIHAPR	SF3A1	611	Q15459
MESALAVPRLPPHDP	L3HYPDH	1	Q96EM0
PPHDPGTPVLSVVDM	L3HYPDH	11	Q96EM0
APEMLPKHPHTPRDR	C12orf42	281	Q96LP6
PPVDPHSLRSLTGMP	CLEC16A	1011	Q2KHT3
THMKPPRTPPGEAEH	C11orf16	436	Q9NQ32
LLGPKREVDMHPPLP	PIAS3	106	Q9Y6X2
PPLMAAEPTAPLSHS	TBC1D24	456	Q9ULP9
SPSPDRFGMLPLDEP	ZC3HC1	161	Q86WB0
HMRVPTIPPNLAGIP	TLE1	426	Q04724
LGMGDSHIPPPVPSE	USPL1	996	Q5W0Q7
APGEMPAPAVHLASP	ZFAT	551	Q9P243
EMARRLHPPSPVPQG	TRIM11	76	Q96F44
ERTHPVPMGTPTPLE	ZNF668	591	Q96K58
TLPPNMHEPIIPRGA	WDFY3	2581	Q8IZQ1
PLPMETGSPPLHDSY	RBMXL3	1026	Q8N7X1
TLPDGPLASPARVPM	SEC16A	1956	O15027
LTLTPDPAPPMAHSP	SPHK2	401	Q9NRA0
SSPVPEEIPRMHPGR	PGF	181	P49763
PSRPLPDAPHGVMDS	SH3PXD2B	466	A1X283
MGNTVHRTLPDPSPP	NEURL1B	1	A8MQ27
PHLAPLSDPEAPSME	ZNF710	221	Q8N1W2
MPPPAEVTDPSHAPA	ZBTB4	1	Q9P1Z0
PPPAAAASPMPLHIT	SLC35A4	171	Q96G79
SPELPRRMETALPGP	TESK1	441	Q15569
PSHPAAALPLPMRGE	STH	106	Q8IWL8
MEALTPPPATHLSPL	TNFRSF25	241	Q93038
LVPMGPGREHLEEPP	PRR33	136	A8MZF0
PGREHLEEPPMAGPA	PRR33	141	A8MZF0
ERMPLPAPSLSHQPP	YLPM1	1791	P49750
MPPPATHLSPALAPV	TRIM9	106	Q9C026
HPLPMTATPRKLPEG	ZBTB9	251	Q96C00
HDTPDMPRSLPLQPG	XPNPEP3	431	Q9NQH7
LHCMLSPPEPSAAPR	VPS9D1	331	Q9Y2B5
PLLMPSVHAARIPAP	VGLL3	261	A8MV65
SLHPSPTLPLPMEGF	HIVEP2	2246	P31629
HPLMDSAVPPIADEP	SEMA6D	396	Q8NFY4
AVIHMAREAPPLPPP	SETBP1	1511	Q9Y6X0
PRPPHPRSSSPEAMD	ZNF580	6	Q9UK33
MSDPHSSPLLPEPLS	SLC14A2	1	Q15849
MLPSAPSAPIRLPHT	ZNF318	741	Q5VUA4
LGDHRKVSPPLMAPP	TMED8	146	Q6PL24
PTVEDPHRMGSPAPL	TNRC6B	1806	Q9UPQ9
MRPAVLGSPDRAPPE	MZF1	1	P28698
PLSHLPTEDPTMERP	NEDD4L	111	Q96PU5