Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	hemoglobin binding	CUBN HBB HBD	3.46e-05	11	121	3	GO:0030492
GeneOntologyMolecularFunction	hemoglobin beta binding	HBB HBD	3.64e-05	2	121	2	GO:0031722
GeneOntologyMolecularFunction	phosphatidylinositol phosphate binding	FLII ANKFY1 TPCN2 WASHC2C TOM1 RPH3A ZFYVE28	2.13e-04	199	121	7	GO:1901981
GeneOntologyMolecularFunction	hemoglobin alpha binding	HBB HBD	3.60e-04	5	121	2	GO:0031721
Domain	Znf_FYVE_PHD	ANKFY1 TCF20 PHF20 BAZ2B NSD1 CHD4 KDM5D RPH3A ZFYVE28 KMT2D KDM2A DNMT3B	1.36e-10	147	117	12	IPR011011
Domain	PHD	TCF20 PHF20 BAZ2B NSD1 CHD4 KDM5D KMT2D KDM2A	8.62e-08	89	117	8	SM00249
Domain	Znf_PHD	TCF20 PHF20 BAZ2B NSD1 CHD4 KDM5D KMT2D KDM2A	1.03e-07	91	117	8	IPR001965
Domain	ZF_PHD_2	TCF20 PHF20 BAZ2B NSD1 CHD4 KDM5D KMT2D KDM2A	1.44e-07	95	117	8	PS50016
Domain	ZF_PHD_1	TCF20 PHF20 BAZ2B NSD1 CHD4 KDM5D KMT2D KDM2A	1.56e-07	96	117	8	PS01359
Domain	Znf_PHD-finger	PHF20 BAZ2B NSD1 CHD4 KDM5D KMT2D KDM2A	6.31e-07	79	117	7	IPR019787
Domain	PHD	PHF20 BAZ2B NSD1 CHD4 KDM5D KMT2D	7.52e-06	75	117	6	PF00628
Domain	-	ANKFY1 HDAC6 PHF20 BAZ2B NSD1 CHD4 KDM5D RPH3A ZFYVE28 KMT2D KDM2A DNMT3B	2.52e-05	449	117	12	3.30.40.10
Domain	Znf_RING/FYVE/PHD	ANKFY1 HDAC6 PHF20 BAZ2B NSD1 CHD4 KDM5D RPH3A ZFYVE28 KMT2D KDM2A DNMT3B	3.13e-05	459	117	12	IPR013083
Domain	Zinc_finger_PHD-type_CS	PHF20 NSD1 CHD4 KDM5D KDM2A	5.42e-05	65	117	5	IPR019786
Domain	Haemoglobin_b	HBB HBD	3.84e-04	5	117	2	IPR002337
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF536 ANKFY1 TCF20 MSANTD2 CHD4 IDH3A TXNL1 KMT2D AHNAK SEC16A MRTFA HOMEZ	3.36e-08	418	123	12	34709266
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	EPRS1 TCF20 MAP4 BAZ2B NSD1 CHD4 PAF1 RFX5 EEF1A1 EEF1A1P5 ZNF512B AHNAK SEC16A HBB HBD TADA3	2.77e-07	954	123	16	36373674
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FLII ABL1 ZNF628 NSD1 TESK1 ITPR2 MSX2 HEYL KMT2D INF2 BTBD7 AHNAK SEC16A NAV2 KCNK5 DOT1L SIPA1L2	3.81e-07	1105	123	17	35748872
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ABL1 TCF20 MAP4 TESK1 EPN2 EEF1A1 SYNJ2 PLEKHG3 SYDE2 AHNAK SEC16A NAV2 SIPA1L2 DOP1A SAMD4A	4.18e-07	861	123	15	36931259
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	FLII EPRS1 MAP4 TOM1 NCAM1 IDH3A RPH3A EPN2 EEF1A1 ITPR2 MAGI2 STXBP1 FAM120A INF2 SEC16A SIPA1L2 HBB HBD PCDH1	6.91e-07	1431	123	19	37142655
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	EPRS1 TBX3 TCF20 PHF20 BAZ2B NSD1 CHD4 PAF1 RFX5 EEF1A1P5 ZNF512B THAP4 KMT2D AHNAK KDM2A TADA3 HOMEZ SAMD4A	7.23e-07	1294	123	18	30804502
Pubmed	Identification of atrogin-1-targeted proteins during the myostatin-induced skeletal muscle wasting.	EPRS1 MAP4 EEF1A1 INF2 AHNAK HBB HBD	1.40e-06	155	123	7	22673621
Pubmed	ZNF410 represses fetal globin by singular control of CHD4.	CHD4 HBB HBD	1.50e-06	7	123	3	33859416
Pubmed	Early mammalian erythropoiesis requires the Dot1L methyltransferase.	DOT1L HBB HBD	1.50e-06	7	123	3	20798234
Pubmed	New nomenclature for chromatin-modifying enzymes.	NSD1 KDM5D KMT2D KDM2A DOT1L	1.84e-06	57	123	5	18022353
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	EPRS1 ZFAND3 TCF20 MAP4 BAZ2B MSANTD2 CHD4 PAF1 RFX5 EEF1A1 THAP4 TXNL1 KMT2D FAM120A TADA3 HOMEZ	1.85e-06	1103	123	16	34189442
Pubmed	Aerobic glycolysis tunes YAP/TAZ transcriptional activity.	EPRS1 MAP4 EEF1A1 EEF1A1P5 FAM120A AHNAK SEC16A	1.89e-06	162	123	7	25796446
Pubmed	Functional proteomics mapping of a human signaling pathway.	TOM1 APLP2 RGS3 EPN2 EEF1A1 ZNF512B HEYL KMT2D TM9SF2 KDM2A PCDH1	8.61e-06	591	123	11	15231748
Pubmed	Activator-mediated recruitment of the MLL2 methyltransferase complex to the beta-globin locus.	KMT2D HBB HBD	9.28e-06	12	123	3	17707229
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BAZ2B WDFY4 AMIGO1 EPN2 SHROOM4 FAM120A PLEKHG3 ARHGAP28 KDM2A DOP1A	1.08e-05	493	123	10	15368895
Pubmed	An E3 ubiquitin ligase, Really Interesting New Gene (RING) Finger 41, is a candidate gene for anxiety-like behavior and beta-carboline-induced seizures.	COG2 HBB HBD	1.20e-05	13	123	3	18986647
Pubmed	Perturbations in lipid metabolism and gut microbiota composition precede cardiac dysfunction in a mouse model of thalassemia.	HBB HBD	1.24e-05	2	123	2	37902616
Pubmed	Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences.	HBB HBD	1.24e-05	2	123	2	270684
Pubmed	Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice.	HBB HBD	1.24e-05	2	123	2	21099112
Pubmed	A large upstream region is not necessary for gene expression or hypersensitive site formation at the mouse beta -globin locus.	HBB HBD	1.24e-05	2	123	2	11121056
Pubmed	Decreased hepcidin mRNA expression in thalassemic mice.	HBB HBD	1.24e-05	2	123	2	14675418
Pubmed	Nucleotide sequences of the mouse globin beta gene cDNAs in a wild derived new haplotype Hbb(w1).	HBB HBD	1.24e-05	2	123	2	10441738
Pubmed	Hematopoietic stem cell function in β-thalassemia is impaired and is rescued by targeting the bone marrow niche.	HBB HBD	1.24e-05	2	123	2	32344432
Pubmed	Responses of primary osteoblasts and osteoclasts from hemizygous β-globin knockout thalassemic mice with elevated plasma glucose to 1,25-dihydroxyvitamin D3.	HBB HBD	1.24e-05	2	123	2	31562377
Pubmed	Effects of human gamma-globin in murine beta-thalassaemia.	HBB HBD	1.24e-05	2	123	2	16803575
Pubmed	The adult beta-globin genes of the "single" type mouse C57BL.	HBB HBD	1.24e-05	2	123	2	7237554
Pubmed	Hepcidin and 1,25(OH)2D3 effectively restore Ca2+ transport in β-thalassemic mice: reciprocal phenomenon of Fe2+ and Ca2+ absorption.	HBB HBD	1.24e-05	2	123	2	27245334
Pubmed	Co-inheritance of alpha- and beta-thalassaemia in mice ameliorates thalassaemic phenotype.	HBB HBD	1.24e-05	2	123	2	17493845
Pubmed	An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression.	HBB HBD	1.24e-05	2	123	2	28641125
Pubmed	A mouse model for beta 0-thalassemia.	HBB HBD	1.24e-05	2	123	2	8524813
Pubmed	Reversal of hemochromatosis by apotransferrin in non-transfused and transfused Hbbth3/+ (heterozygous B1/B2 globin gene deletion) mice.	HBB HBD	1.24e-05	2	123	2	25616571
Pubmed	Neutralizing the function of a β-globin-associated cis-regulatory DNA element using an artificial zinc finger DNA-binding domain.	HBB HBD	1.24e-05	2	123	2	23074246
Pubmed	High phosphate intake induces bone loss in nephrectomized thalassemic mice.	HBB HBD	1.24e-05	2	123	2	35622784
Pubmed	A humanized mouse model for a common beta0-thalassemia mutation.	HBB HBD	1.24e-05	2	123	2	15780748
Pubmed	Evolution of the mouse beta-globin genes: a recent gene conversion in the Hbbs haplotype.	HBB HBD	1.24e-05	2	123	2	3870864
Pubmed	Molecular characterization of (deltabeta)(0)/beta(0)-thalassemia and (deltabeta)(0)-thalassemia/hemoglobin E in Thai patients.	HBB HBD	1.24e-05	2	123	2	11860449
Pubmed	Model mice for Presbyterian hemoglobinopathy (Asn(beta108)-->Lys) confer hemolytic anemia with altered oxygen affinity and instability of Hb.	HBB HBD	1.24e-05	2	123	2	12127975
Pubmed	The chromatin "landscape" of a murine adult β-globin gene is unaffected by deletion of either the gene promoter or a downstream enhancer.	HBB HBD	1.24e-05	2	123	2	24817273
Pubmed	Ligation-mediated amplification of RNA from murine erythroid cells reveals a novel class of beta globin mRNA with an extended 5'-untranslated region.	HBB HBD	1.24e-05	2	123	2	8041612
Pubmed	A 66-base pair insert bridges the deletion responsible for a mouse model of beta-thalassemia.	HBB HBD	1.24e-05	2	123	2	3017971
Pubmed	Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene.	HBB HBD	1.24e-05	2	123	2	273235
Pubmed	Mild-intensity physical activity prevents cardiac and osseous iron deposition without affecting bone mechanical property or porosity in thalassemic mice.	HBB HBD	1.24e-05	2	123	2	35396390
Pubmed	Molecular characterization of a novel homozygous deletion in β-globin cluster causing (δβ)0-Thalassemia among Tunisian family.	HBB HBD	1.24e-05	2	123	2	36214153
Pubmed	The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA.	HBB HBD	1.24e-05	2	123	2	728996
Pubmed	CNTO 530 increases expression of HbA and HbF in murine models of β-thalassemia and sickle cell anemia.	HBB HBD	1.24e-05	2	123	2	23157711
Pubmed	HbA2-Partinico or delta(A2)Pro-->Thr, a new genetic variation in the delta-globin gene in cis to the beta(+) thal IVS-I-110 G>A, and the heterogeneity of delta-globin alleles in double heterozygotes for beta- and delta-globin gene defects.	HBB HBD	1.24e-05	2	123	2	19609526
Pubmed	Discovery of a new HBB haplotype w2 in a wild-derived house mouse, Mus musculus.	HBB HBD	1.24e-05	2	123	2	18299925
Pubmed	Transposition of a long member of the L1 major interspersed DNA family into the mouse beta globin gene locus.	HBB HBD	1.24e-05	2	123	2	2991851
Pubmed	A negative regulatory sequence near the mouse beta-maj globin gene associated with a region of potential Z-DNA.	HBB HBD	1.24e-05	2	123	2	6086313
Pubmed	Thrombocytopenia and erythrocytosis in mice with a mutation in the gene encoding the hemoglobin β minor chain.	HBB HBD	1.24e-05	2	123	2	22203977
Pubmed	A humanized BAC transgenic/knockout mouse model for HbE/beta-thalassemia.	HBB HBD	1.24e-05	2	123	2	16631345
Pubmed	A novel murine model of Cooley anemia and its rescue by lentiviral-mediated human beta-globin gene transfer.	HBB HBD	1.24e-05	2	123	2	12480689
Pubmed	Comparison of total sequence of a cloned rabbit beta-globin gene and its flanking regions with a homologous mouse sequence.	HBB HBD	1.24e-05	2	123	2	482942
Pubmed	Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity.	HBB HBD	1.24e-05	2	123	2	11830454
Pubmed	Second generation knockout sickle mice: the effect of HbF.	HBB HBD	1.24e-05	2	123	2	11154217
Pubmed	The complete nucleotide sequence of a beta-globin-like structure, beta h2, from the [Hbb]d mouse BALB/c.	HBB HBD	1.24e-05	2	123	2	6736028
Pubmed	Running exercise alleviates trabecular bone loss and osteopenia in hemizygous β-globin knockout thalassemic mice.	HBB HBD	1.24e-05	2	123	2	24780610
Pubmed	First report on the co-inheritance of beta-globin IVS-I-5 (G-->C) thalassemia with delta globin CD12 {Asn-->Lys (AAT-->AAA)}HbA₂-NYU in Iran.	HBB HBD	1.24e-05	2	123	2	21194254
Pubmed	Significance of borderline hemoglobin A2 values in an Italian population with a high prevalence of beta-thalassemia.	HBB HBD	1.24e-05	2	123	2	18603555
Pubmed	Comparison of cloned rabbit and mouse beta-globin genes showing strong evolutionary divergence of two homologous pairs of introns.	HBB HBD	1.24e-05	2	123	2	264241
Pubmed	Lack of neighborhood effects from a transcriptionally active phosphoglycerate kinase-neo cassette located between the murine beta-major and beta-minor globin genes.	HBB HBD	1.24e-05	2	123	2	11418464
Pubmed	Mechanisms of enhanced thrombus formation in cerebral microvessels of mice expressing hemoglobin-S.	HBB HBD	1.24e-05	2	123	2	21304105
Pubmed	In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia.	HBB HBD	1.24e-05	2	123	2	30422819
Pubmed	β-Globin cis-elements determine differential nuclear targeting through epigenetic modifications.	HBB HBD	1.24e-05	2	123	2	24297746
Pubmed	Cloning and amplification of alpha and beta mouse globin gene sequences synthesised in vitro.	HBB HBD	1.24e-05	2	123	2	338418
Pubmed	Nephrectomy Does not Exacerbate Cancellous Bone loss in Thalassemic Mice.	HBB HBD	1.24e-05	2	123	2	32385316
Pubmed	The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes.	HBB HBD	1.24e-05	2	123	2	519759
Pubmed	Humanized beta-thalassemia mouse model containing the common IVSI-110 splicing mutation.	HBB HBD	1.24e-05	2	123	2	16421096
Pubmed	Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy.	HBB HBD	1.24e-05	2	123	2	7935410
Pubmed	Successful treatment of murine beta-thalassemia intermedia by transfer of the human beta-globin gene.	HBB HBD	1.24e-05	2	123	2	11877258
Pubmed	Tracking of mouse cell lineage using microinjected DNA sequences: analyses using genomic Southern blotting and tissue-section in situ hybridizations.	HBB HBD	1.24e-05	2	123	2	3428512
Pubmed	ABL1-dependent OTULIN phosphorylation promotes genotoxic Wnt/β-catenin activation to enhance drug resistance in breast cancers.	ABL1 OTULIN	1.24e-05	2	123	2	32770022
Pubmed	The molecular characterization of an A:T to G:C transition in the Hbb-b1 gene of the murine homologue of hemoglobin Rainier.	HBB HBD	1.24e-05	2	123	2	1820025
Pubmed	Super-resolution imaging reveals three-dimensional folding dynamics of the β-globin locus upon gene activation.	HBB HBD	1.24e-05	2	123	2	22767512
Pubmed	Transgene copy number-dependent rescue of murine beta-globin knockout mice carrying a 183 kb human beta-globin BAC genomic fragment.	HBB HBD	1.24e-05	2	123	2	15820143
Pubmed	The beta-delta crossover leading to the beta delta hybrid gene of hemoglobin P-Nilotic is located within 54 base-pairs of the 5' end of exon 2 or between codons 31 and 50.	HBB HBD	1.24e-05	2	123	2	3620470
Pubmed	The sequence of the chromosomal mouse beta-globin major gene: homologies in capping, splicing and poly(A) sites.	HBB HBD	1.24e-05	2	123	2	569555
Pubmed	The pyruvate kinase activator mitapivat reduces hemolysis and improves anemia in a β-thalassemia mouse model.	HBB HBD	1.24e-05	2	123	2	33822774
Pubmed	Evaluation of Stem Cell-Derived Red Blood Cells as a Transfusion Product Using a Novel Animal Model.	HBB HBD	1.24e-05	2	123	2	27959920
Pubmed	Mouse haemoglobin beta chains. Comparative sequence data on adult major and minor beta chains from two species, Mus musculus and Mus cervicolor.	HBB HBD	1.24e-05	2	123	2	999642
Pubmed	Integrated protein quality-control pathways regulate free α-globin in murine β-thalassemia.	HBB HBD	1.24e-05	2	123	2	22427201
Pubmed	Heparanase Level and Procoagulant Activity Are Increased in Thalassemia and Attenuated by Janus Kinase 2 Inhibition.	HBB HBD	1.24e-05	2	123	2	32745462
Pubmed	Expression of HbC and HbS, but not HbA, results in activation of K-Cl cotransport activity in transgenic mouse red cells.	HBB HBD	1.24e-05	2	123	2	14615383
Pubmed	Hemoglobin induction in mouse macrophages.	HBB HBD	1.24e-05	2	123	2	10359765
Pubmed	Evolution of duplicated beta-globin genes and the structural basis of hemoglobin isoform differentiation in Mus.	HBB HBD	1.24e-05	2	123	2	19675095
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FLII EPRS1 COG2 HDAC6 CHD4 RFX5 RPH3A EEF1A1 ZNF512B THAP4 MAGI2 STXBP1 FAM120A MVP ECE2 SOS2	1.27e-05	1285	123	16	35914814
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	FLII EPRS1 HDAC6 WASHC2C MAP4 TACC2 FAM120A SEC16A NAV2 MRTFA	1.28e-05	503	123	10	16964243
Pubmed	TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77.	HDAC6 CHD4 EEF1A1	1.90e-05	15	123	3	19321449
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	COL5A1 ZFAND3 ZNF444 TPCN2 IMPA2 MAP4 TOM1 THAP4 FAM120A SYNJ2 INF2 PLEKHG3 KDM2A PCDH1 NBR1 DOP1A SOS2	2.02e-05	1489	123	17	28611215
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FLII EPRS1 EXO5 HDAC6 WASHC2C TCF20 MAP4 CHD4 KMT2D SEC16A MRTFA HOMEZ	2.05e-05	774	123	12	15302935
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	HDAC6 BAZ2B CHD4 KDM5D KMT2D DNMT3B	2.11e-05	157	123	6	30186101
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	EPRS1 TCF20 MAP4 NSD1 PAF1 KMT2D AHNAK SEC16A KDM2A DOT1L	2.70e-05	549	123	10	38280479
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	NSD1 KDM5D KDM2A DOT1L	2.79e-05	49	123	4	34368113
Pubmed	The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.	EPRS1 MAP4 NCAM1 IDH3A RPH3A EEF1A1 STXBP1 FAM120A HBB HBD	2.82e-05	552	123	10	36293380
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	EPRS1 DNAH3 MAP4 CHD4 KDM5D EEF1A1 TG FAM120A AHNAK HBB MVP SOS2	2.93e-05	803	123	12	36517590
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	EPRS1 ZFAND3 HDAC6 WASHC2C MAP4 NSD1 TACC2 CUBN WDFY4 INF2 RNASEH2C SEC16A DOT1L MRTFA	3.09e-05	1084	123	14	11544199
Pubmed	Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.	NCAM1 IDH3A EEF1A1 STXBP1 HBB HBD	3.20e-05	169	123	6	17634366
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	ZNF536 TACC2 TPGS2 CRACR2B MAGI2 TM9SF2 RP1L1 MACROD2 NAV2 KCNK5 ARHGAP28 SAMD4A	3.34e-05	814	123	12	23251661
Pubmed	An erythroid chaperone that facilitates folding of alpha-globin subunits for hemoglobin synthesis.	HBB HBD	3.71e-05	3	123	2	17607360
Pubmed	Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice.	HBB HBD	3.71e-05	3	123	2	28151426
Cytoband	Ensembl 112 genes in cytogenetic band chr9q34	COL5A1 ABL1 CEL EEF1A1P5 STXBP1 SEC16A	2.55e-04	325	123	6	chr9q34
GeneFamily	PHD finger proteins	PHF20 BAZ2B NSD1 CHD4 KDM5D KMT2D KDM2A	1.19e-07	90	78	7	88
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	NSD1 KMT2D DOT1L	4.20e-04	34	78	3	487
GeneFamily	PDZ domain containing	RGS3 SHROOM4 MAGI2 AHNAK SIPA1L2	5.07e-04	152	78	5	1220
GeneFamily	Hemoglobin subunits	HBB HBD	8.09e-04	10	78	2	940
GeneFamily	PWWP domain containing	NSD1 DNMT3B	4.01e-03	22	78	2	1147
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM5D KDM2A	4.77e-03	24	78	2	485
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	ANKFY1 ZFYVE28	7.88e-03	31	78	2	81
GeneFamily	Phosphoinositide phosphatases	IMPA2 SYNJ2	8.38e-03	32	78	2	1079
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL5A1 TBX3 ZNF536 TACC2 SYNJ2 NAV2 MRTFA SAMD4A	5.15e-08	185	124	8	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC6 NSD1 CHD4 KDM5D STXBP1 FAM120A SEC16A NAV2	7.73e-08	195	124	8	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD1 APLP2 CRACR2B RGS3 ITPR2 SHROOM4 AHNAK	9.23e-07	186	124	7	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL5A1 TBX3 ZNF536 NCAM1 PTH1R MAGI2 ARHGAP28	9.57e-07	187	124	7	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	COL5A1 TBX3 COL15A1 CHD4 ITPR2 FAM120A AHNAK	1.50e-06	200	124	7	5ba4ed490c64b3bb738e7729669f893fa73aa56f
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A1 COL15A1 ZFP69 PTH1R HEYL KDM2A	1.10e-05	179	124	6	ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCell	RA-16._Neuronal\|RA / Chamber and Cluster_Paper	TBX3 ZNF536 NPTX2 NCAM1 AHNAK KCNK5	1.14e-05	180	124	6	5842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCell	RA-16._Neuronal\|World / Chamber and Cluster_Paper	TBX3 ZNF536 NPTX2 NCAM1 AHNAK KCNK5	1.18e-05	181	124	6	7d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL5A1 TBX3 ZNF536 TACC2 PTH1R SAMD4A	1.21e-05	182	124	6	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL5A1 TBX3 ZNF536 COL15A1 TACC2 NAV2	1.46e-05	188	124	6	4d1e5f85342ae550086609d7680e32730b78b5d2
ToppCell	wk_08-11-Epithelial-PNS-Early_Schwann\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ZNF536 NPTX2 TPCN2 NCAM1 HEYL KCNK5	1.55e-05	190	124	6	8190674a48607984726974765aafbca116f437e0
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 ERICH3 COL15A1 HSF5 MSX2 HEYL	1.55e-05	190	124	6	8a53f4d3c9aca45b5826f53f7dcdfb8bc8280acb
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A1 ZFAND3 SYNJ2 DOT1L MRTFA SAMD4A	1.64e-05	192	124	6	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	ZNF536 NCAM1 TACC2 RGS3 MYO18B SAMD4A	1.74e-05	194	124	6	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC6 CHD4 KDM5D FAM120A SEC16A NAV2	1.79e-05	195	124	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL5A1 NPTX2 NCAM1 RGS3 PTH1R MAGI2	1.85e-05	196	124	6	760885dc608c82768fe0decd63ed9fda8315f453
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 ERICH3 TM9SF2 AHNAK HBB PCDH1	1.90e-05	197	124	6	5c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL5A1 COL15A1 NCAM1 RGS3 PTH1R HEYL	1.90e-05	197	124	6	63b63c6b2f842adb87bc83222ff86796bd9b58f6
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL5A1 COL15A1 NCAM1 RGS3 PTH1R HEYL	1.90e-05	197	124	6	fb50903b87498b400c8e16e6a561b6d9458e5d97
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 ZNF536 NPTX2 HEYL KCNK5 PCDH1	1.95e-05	198	124	6	c8272ac4d90f2367f538f66db40de911ad73ea7f
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	COL15A1 TACC2 MCTP1 SYNJ2 NAV2 SAMD4A	1.95e-05	198	124	6	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP4 SHROOM4 STXBP1 MCTP1 AHNAK SIPA1L2	2.07e-05	200	124	6	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP4 SHROOM4 STXBP1 MCTP1 AHNAK SIPA1L2	2.07e-05	200	124	6	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	ZNF536 HTR3A BAZ2B KDM5D RPH3A EPN2	2.07e-05	200	124	6	e16bde12326f0cfc4d03f9307cba0e21ea2389cb
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-immature_T_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPCN2 NCAM1 KDM5D C3orf33 NAV2	3.43e-05	132	124	5	9936078c328b1e1d59f9dfdd69d36926a0cdaf0d
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NPTX2 HBD PTH1R SMTNL1 HBB	5.55e-05	146	124	5	03a6a442f1f6d173a41aeebbfe41ee08853d9585
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Cpa6\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COL5A1 SPTBN5 MCTP1 INF2 AHNAK	7.14e-05	154	124	5	12cbc38bc1f7231c67e1d2d5e86e95bc12e24682
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBX3 SH3D21 ITPR2 HEYL PLEKHG3	7.36e-05	155	124	5	ced64e26962c5c6e6d539f361fe57ab0b399e999
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBX3 SH3D21 ITPR2 HEYL PLEKHG3	7.36e-05	155	124	5	0f24ef6486aef354f0911c06932cb01d1a0525ac
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell-Peri\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBX3 SH3D21 ITPR2 HEYL PLEKHG3	7.36e-05	155	124	5	d8b5145258f075b15080f8739f537f48dd22225e
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_CT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COL5A1 SPTBN5 MCTP1 INF2 AHNAK	7.59e-05	156	124	5	fe383ce3a0c37f7343d7026cb51260a04d4c2829
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Crispld2_(Neuron.Gad1Gad2.Synpr-Crispld2)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	COL15A1 HTR3A C3orf62 TG	8.14e-05	82	124	4	7f0ee8dafc37c3628506397f88fbb98fc6420bfb
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Crispld2_(Neuron.Gad1Gad2.Synpr-Crispld2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	COL15A1 HTR3A C3orf62 TG	8.14e-05	82	124	4	c8242d273513e99107c154afb489980d11008555
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	MAP4 PAF1 WDFY4 STXBP3 AHNAK	9.07e-05	162	124	5	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_bronchial_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL15A1 RGS3 MCTP1 RP1L1 MVP	1.02e-04	166	124	5	a697460dfe72e08fbf7d8e734a16b7dd2c6d86f9
ToppCell	Adult-Mesenchymal-myofibroblast_cell\|Adult / Lineage, Cell type, age group and donor	COL5A1 ZNF536 PTH1R HEYL SYNJ2	1.05e-04	167	124	5	d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCell	droplet-Fat-Bat-18m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXO5 KDM5D ZFP69 TG IGSF23	1.08e-04	168	124	5	6fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP4 TACC2 SH3D21 INF2 AHNAK	1.08e-04	168	124	5	03896466698a79f7f1ad862cb7e05585260e2a5a
ToppCell	droplet-Fat-Bat-18m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXO5 KDM5D ZFP69 TG IGSF23	1.08e-04	168	124	5	794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCell	droplet-Fat-Bat-18m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EXO5 KDM5D ZFP69 TG IGSF23	1.08e-04	168	124	5	1e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCell	Mesenchymal_cells-Osteo-CAR\|Mesenchymal_cells / Lineage and Cell class	NCAM1 WDFY4 RGS3 PTH1R NAV2	1.27e-04	174	124	5	430e3cd61bc2a471959faa40e817aa4dd7d82d28
ToppCell	droplet-Kidney-nan-21m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APLP2 CUBN THAP4 TM9SF2 CDH16	1.34e-04	176	124	5	0475db3f860de1e216cbdeb886f7a75b9f4fc801
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	COL5A1 PHF20 SHROOM4 HEYL KDM2A	1.41e-04	178	124	5	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL5A1 COL15A1 NCAM1 PTH1R MAGI2	1.49e-04	180	124	5	f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCell	IIH-CD8-CD4_Treg\|IIH / Condition, Cell_class and T cell subcluster	AMIGO1 ZNF512B SHROOM4 PLEKHG3 HBB	1.49e-04	180	124	5	d1a8b25115c80e5a5bd0b8244167a98250ab9778
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TBX3 ZNF536 NCAM1 TACC2 ARHGAP28	1.52e-04	181	124	5	25915e2500430a902db37d79a749ce2990b69810
ToppCell	NS-critical-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IMPA2 PAF1 ITPR2 SYDE2 PCDH1	1.52e-04	181	124	5	cfc3ed541d93158ce26641ea30b7573d93600a11
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TBX3 ZFP69 SHROOM4 STXBP1 PCDH1	1.52e-04	181	124	5	9cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL15A1 RGS3 MCTP1 SYNJ2 PCDH1	1.56e-04	182	124	5	0346f81bbb1f309f3e9d063b20547d548d09472c
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF536 NCAM1 MACROD2 NAV2 KCNK5	1.56e-04	182	124	5	6fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 MAGI2 SYNJ2 INF2 ARHGAP28	1.60e-04	183	124	5	848fc6dd129150897ee339343e83c645b6e779eb
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	IDH3A WDFY4 MACROD2 DOP1A SAMD4A	1.60e-04	183	124	5	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TBX3 COL15A1 PTH1R HEYL AHNAK	1.65e-04	184	124	5	9f524f0a1e7eb50e3b97a35c0ea7e183a4e99aa8
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	MAP4 NCAM1 TACC2 MYO18B SAMD4A	1.65e-04	184	124	5	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TBX3 COL15A1 PTH1R HEYL AHNAK	1.65e-04	184	124	5	779016341dbd6d54b5fdb8711692d31a9b2cec4b
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF536 HTR3A CALY ARHGAP28 ECE2	1.69e-04	185	124	5	16e9ccea0e3b95d90dc48ef74206c805681dac0b
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERICH3 HTR3A RPH3A CALY ECE2	1.73e-04	186	124	5	18fd311252299d6d30ddb32002ed069056108206
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TBX3 ZNF536 PTH1R MAGI2 SAMD4A	1.73e-04	186	124	5	e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 MAGI2 SYNJ2 PLEKHG3 SIPA1L2	1.82e-04	188	124	5	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TBX3 ZNF536 NPTX2 COL15A1 NCAM1	1.82e-04	188	124	5	c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF536 MAGI2 SYNJ2 PLEKHG3 SIPA1L2	1.82e-04	188	124	5	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	(0)_NK_CD160pos\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	COG2 BAZ2B NCAM1 CRACR2B RGS3	1.86e-04	189	124	5	713991025bb92d38cb0507ff01fd91b48c8af45a
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	COL5A1 TBX3 ZNF536 PTH1R ARHGAP28	1.86e-04	189	124	5	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	droplet-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 NCAM1 CRACR2B STXBP1 PCDH1	1.86e-04	189	124	5	7b6cb745c0a637d6addc105a79059ed488fced39
ToppCell	droplet-Tongue-nan-24m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 ERICH3 HSF5 MSX2 HEYL	1.91e-04	190	124	5	86ab845a7fae2111c0b01e1aec235e19c4c0ef5c
ToppCell	droplet-Tongue-nan-3m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 ERICH3 HSF5 MSX2 HEYL	1.91e-04	190	124	5	251e3a33041023bfc4b547c7eb68cfb8f421636f
ToppCell	lymphoid-NK_cell-TNFRSF18+IL7R+_NK_cell\|NK_cell / Lineage, cell class and subclass	HBD INF2 RNASEH2C EID1 HBB	1.91e-04	190	124	5	16e408436fa663cdf86e38311a7aed4e02c28579
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KDM5D KMT2D MCTP1 SYNJ2 PLEKHG3	1.91e-04	190	124	5	3f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	NCAM1 TACC2 MACROD2 MYO18B SAMD4A	1.96e-04	191	124	5	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	NCAM1 TACC2 RGS3 MYO18B SAMD4A	1.96e-04	191	124	5	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	NCAM1 TACC2 MACROD2 MYO18B SAMD4A	2.01e-04	192	124	5	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TBX3 ZNF536 NCAM1 PTH1R ARHGAP28	2.01e-04	192	124	5	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KDM5D KMT2D MCTP1 SYNJ2 PLEKHG3	2.01e-04	192	124	5	c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 APLP2 CRACR2B EPN2 PCDH1	2.05e-04	193	124	5	2218833749576ba1a0fc95bd155c781e7e1163c6
ToppCell	Control-Myeloid-Monocyte-derived_macrophages\|Control / group, cell type (main and fine annotations)	WASHC2C DISC1 WDFY4 ITPR2 MCTP1	2.05e-04	193	124	5	a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCell	E15.5-Mesenchymal-myocytic_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TBX3 ZNF536 NPTX2 PTH1R HEYL	2.05e-04	193	124	5	3316d6a39abb6a518d45b846254325fc7a8b2035
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 BAZ2B SHROOM4 MCTP1 SIPA1L2	2.05e-04	193	124	5	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 BAZ2B SHROOM4 MCTP1 SIPA1L2	2.05e-04	193	124	5	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 BAZ2B SHROOM4 MCTP1 SIPA1L2	2.05e-04	193	124	5	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL5A1 PTH1R MAGI2 NAV2 ARHGAP28	2.05e-04	193	124	5	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BAZ2B SHROOM4 STXBP1 MCTP1 SIPA1L2	2.10e-04	194	124	5	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	facs-Lung-Endomucin_-18m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 APLP2 CRACR2B EPN2 PCDH1	2.10e-04	194	124	5	df56e23f1dcf1902d29392fcc947e0e268e1648b
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL5A1 NCAM1 RGS3 PTH1R MAGI2	2.10e-04	194	124	5	292ce9021678534c9eedb367b9772a9d976208a8
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	NCAM1 TACC2 RGS3 MYO18B SAMD4A	2.10e-04	194	124	5	c3535f7cc0076653c72db582047cff053c322397
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical\|TCGA-Thryoid / Sample_Type by Project: Shred V9	FLII SHROOM4 INF2 SIPA1L2 MVP	2.10e-04	194	124	5	b46c54802b8d1e0a0a17f9ed8e82eaf5e7f4849d
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	NCAM1 TACC2 MACROD2 MYO18B SAMD4A	2.15e-04	195	124	5	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAM1 EEF1A1 HEYL NAV2 SAMD4A	2.15e-04	195	124	5	5ed995717bd3d35cd66442e6e84fe18fe0f7cf96
ToppCell	Fibroblast-B_(Myofibroblast)\|World / shred on cell class and cell subclass (v4)	COL5A1 ZNF536 COL15A1 PTH1R SAMD4A	2.15e-04	195	124	5	a8d6416518f226e1ec2d6bdc9d4b90cef5cb1365
ToppCell	PCW_05-06-Mesenchymal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL5A1 TBX3 PTH1R MAGI2 ARHGAP28	2.21e-04	196	124	5	dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CEL RGS3 PTH1R NAV2 CDH16	2.21e-04	196	124	5	f40d10ea7714067585493fdc89744714aa427de8
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A1 TBX3 ZNF536 COL15A1 SAMD4A	2.21e-04	196	124	5	9d7b631f24a19a7dc7a28f28525d4019fc8fcf8a
ToppCell	MatrixFB-Fibroblast-B_(Myofibroblast)\|MatrixFB / shred on cell class and cell subclass (v4)	COL5A1 TBX3 ZNF536 COL15A1 SAMD4A	2.21e-04	196	124	5	38ea0eaf42f95c321ca23570d0d7752980cf00f8
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A1 TBX3 ZNF536 COL15A1 SAMD4A	2.26e-04	197	124	5	7d97c2d51a543c02d679e9257b22d0581e73a11d
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 ZNF536 NPTX2 HEYL KCNK5	2.26e-04	197	124	5	bb35a2b7320fda92e9cd42f536b7bd54e3a73a32
ToppCell	facs-Brain_Non-Myeloid\|facs / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAM1 APLP2 EPN2 INF2 AHNAK	2.26e-04	197	124	5	a1f7eec1aca03432caa8fe817ff6d24b29d4062d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	APLP2 EEF1A1 EID1 HBB CDH16	2.26e-04	197	124	5	02cc9d39afefa5e5b6f5d93f9adc3a20050b70dd
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A1 TBX3 ZNF536 COL15A1 SAMD4A	2.26e-04	197	124	5	671d6b5effbac2dd71d18f48d23c523738db1828
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A1 ZNF536 COL15A1 PTH1R SAMD4A	2.26e-04	197	124	5	9d7a1c7dc70ba5e35645f19f9e056e4fa2494aa0
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A1 ZNF536 COL15A1 PTH1R SAMD4A	2.26e-04	197	124	5	090a251194da3e2806989d9a522588f83f52da7f
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A1 ZNF536 COL15A1 PTH1R SAMD4A	2.26e-04	197	124	5	43b5f8e917506c1717f9311584901b506ffd2c79
Drug	Isopropamide iodide [71-81-8]; Down 200; 8.4uM; MCF7; HT_HG-U133A	COL5A1 DNAH3 ZNF444 MAP4 DISC1 EPN2 BTBD7 TADA3 MRTFA SAMD4A SOS2	1.02e-08	197	123	11	6781_DN
Drug	Etilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; HL60; HT_HG-U133A	COL15A1 NSD1 SYNJ2 INF2 AHNAK KCNK5 MRTFA SOS2	1.03e-05	193	123	8	2930_DN
Drug	Dirithromycin [62013-04-1]; Up 200; 4.8uM; MCF7; HT_HG-U133A	NPTX2 PHF20 SH3D21 PLEKHG3 BTBD7 PCDH1 DOP1A SAMD4A	1.07e-05	194	123	8	2863_UP
Drug	Coralyne chloride hydrate [38989-38-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A	COL5A1 MAP4 DISC1 EPN2 ITPR2 SYNJ2 BTBD7 SOS2	1.16e-05	196	123	8	5418_DN
Drug	Zuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; HL60; HT_HG-U133A	CEL DISC1 IDH3A ITPR2 FAM120A INF2 AHNAK EID1	1.16e-05	196	123	8	2936_DN
Drug	Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; PC3; HT_HG-U133A	PHF20 CENPO RGS3 SPTBN5 ARHGAP28 MRTFA CCDC40 SOS2	1.20e-05	197	123	8	4598_UP
Drug	Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; PC3; HT_HG-U133A	COL5A1 NPTX2 HDAC6 SH3D21 SPTBN5 ARHGAP28 SAMD4A SOS2	1.20e-05	197	123	8	3801_UP
Drug	Riboflavine [83-88-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A	TBX3 MAP4 RPH3A SH3D21 EPN2 ITPR2 MAGI2 CCDC40	1.24e-05	198	123	8	2760_UP
Drug	Edrophonium chloride [116-38-1]; Up 200; 19.8uM; MCF7; HT_HG-U133A	EXO5 MAP4 CENPO SH3D21 SYNJ2 MRTFA DOP1A SOS2	1.24e-05	198	123	8	1519_UP
Drug	Methiazole; Up 200; 15uM; MCF7; HT_HG-U133A	HDAC6 PHF20 CEL CENPO RPH3A EPN2 AHNAK SAMD4A	1.29e-05	199	123	8	3878_UP
Drug	AC1LADZE	ABL1 HBB HBD	1.80e-05	10	123	3	CID000486298
Drug	tricapryl(methyl)ammonium	HBB HBD	2.89e-05	2	123	2	CID011071504
Drug	allyl 2,4,6-tribromophenyl ether	HBB HBD	2.89e-05	2	123	2	CID000076767
Drug	1,3,5-tribromobenzene	HBB HBD	2.89e-05	2	123	2	CID000012279
Drug	2-(alpha-hydroxybenzyl)-benzimidazole	HBB HBD	2.89e-05	2	123	2	CID000005792
Drug	NSC-334295	HBB HBD	2.89e-05	2	123	2	CID000100107
Drug	AC1L3OJQ	HBB HBD	2.89e-05	2	123	2	CID000119294
Drug	pentabromobenzene	HBB HBD	2.89e-05	2	123	2	CID000011854
Drug	tribromobenzene	HBB HBD	2.89e-05	2	123	2	CID000011842
Drug	Bromkal 73-5 PE	HBB HBD	2.89e-05	2	123	2	CID000118216
Drug	cerium dimer	NSD1 TMEM245 HBB HBD	4.67e-05	37	123	4	CID000139339
Drug	L-870,810	KDM5D HBB HBD	6.68e-05	15	123	3	CID000457930
Drug	wortmannin; Down 200; 1uM; MCF7; HT_HG-U133A_EA	DNAH3 ZNF444 EXO5 MAP4 EBLN2 SAMD4A SOS2	7.67e-05	189	123	7	869_DN
Drug	Gm(5')ppp	EEF1A1 HBB HBD	8.18e-05	16	123	3	CID000173813
Drug	LY294002; Up 200; 10uM; PC3; HT_HG-U133A	COL5A1 SH3D21 AHNAK ARHGAP28 TADA3 SAMD4A SOS2	8.19e-05	191	123	7	5970_UP
Drug	furyl-dihydropyridine I	HBB HBD	8.65e-05	3	123	2	CID000125806
Drug	pentabromoethylbenzene	HBB HBD	8.65e-05	3	123	2	CID000006800
Drug	Nx-D	HBB HBD	8.65e-05	3	123	2	CID006914638
Drug	mer13	HBB HBD	8.65e-05	3	123	2	CID000107453
Drug	BTBPE	HBB HBD	8.65e-05	3	123	2	CID000037840
Drug	Carcinine [56897-53-1]; Down 200; 22uM; MCF7; HT_HG-U133A	DNAH3 EXO5 MAP4 SYNJ2 MVP DOP1A SOS2	8.75e-05	193	123	7	3242_DN
Drug	Butoconazole nitrate [32872-77-1]; Down 200; 8.4uM; HL60; HT_HG-U133A	DNAH3 ZNF444 MAP4 TESK1 ITPR2 AHNAK TADA3	9.03e-05	194	123	7	2427_DN
Drug	Nitrofurantoin [67-20-9]; Down 200; 16.8uM; PC3; HT_HG-U133A	PHF20 MAP4 PLEKHG3 BTBD7 TADA3 MRTFA SOS2	9.03e-05	194	123	7	3674_DN
Drug	Omeprazole [73590-58-6]; Down 200; 11.6uM; HL60; HT_HG-U133A	ZFAND3 ANKFY1 PHF20 MAP4 MSANTD2 INF2 DNMT3B	9.03e-05	194	123	7	2467_DN
Drug	2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A	COL5A1 MAP4 APLP2 STXBP1 MVP MRTFA SOS2	9.33e-05	195	123	7	6999_UP
Drug	Chelidonine monohydrate (+) [476-32-4]; Up 200; 10.8uM; PC3; HT_HG-U133A	HEYL PLEKHG3 AHNAK ARHGAP28 MRTFA SAMD4A SOS2	9.33e-05	195	123	7	5760_UP
Drug	Berberine chloride [633-65-8]; Up 200; 10.8uM; MCF7; HT_HG-U133A	COL5A1 PHF20 MAP4 ITPR2 KMT2D SYNJ2 BTBD7	9.33e-05	195	123	7	2770_UP
Drug	Amitryptiline hydrochloride [549-18-8]; Down 200; 12.8uM; PC3; HT_HG-U133A	DNAH3 DISC1 TOM1 CHD4 ZNF512B INF2 PLEKHG3	9.33e-05	195	123	7	1823_DN
Drug	H-89, Dihydrochloride; Down 200; 0.5uM; PC3; HT_HG-U133A	FLII SYNJ2 PLEKHG3 BTBD7 KCNK5 HBB PCDH1	9.63e-05	196	123	7	6873_DN
Drug	N-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; MCF7; HT_HG-U133A	DNAH3 DISC1 TOM1 RGS3 MCTP1 MRTFA SAMD4A	9.63e-05	196	123	7	6462_DN
Drug	Deferoxamine mesylate [138-14-7]; Down 200; 6uM; PC3; HT_HG-U133A	COL5A1 ZNF444 PHF20 DISC1 CHD4 SYNJ2 SOS2	9.63e-05	196	123	7	3760_DN
Drug	haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A_EA	COL5A1 MAP4 BAZ2B TACC2 INF2 KDM2A SOS2	9.63e-05	196	123	7	1082_UP
Drug	Trioxsalen [3902-71-4]; Down 200; 17.6uM; HL60; HT_HG-U133A	DNAH3 MAP4 INF2 KCNK5 KDM2A MRTFA SOS2	9.63e-05	196	123	7	2516_DN
Drug	S-1360	KDM5D HBB HBD	9.90e-05	17	123	3	CID006451047
Drug	Cefotiam hydrochloride; Down 200; 7.2uM; MCF7; HT_HG-U133A	APLP2 SYNJ2 BTBD7 KCNK5 MVP SAMD4A SOS2	9.94e-05	197	123	7	3319_DN
Drug	Gelsemine [509-15-9]; Up 200; 12.4uM; PC3; HT_HG-U133A	ADAM20 DISC1 ITPR2 PLEKHG3 HBB PCDH1 CCDC40	9.94e-05	197	123	7	4097_UP
Drug	rosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A	DNAH3 ZNF444 ANKFY1 MAP4 EPN2 SYNJ2 BTBD7	9.94e-05	197	123	7	1658_DN
Drug	Clopamide [636-54-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A	BAZ2B MCTP1 HBB PCDH1 MRTFA CCDC40 SOS2	9.94e-05	197	123	7	5402_UP
Drug	2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; HL60; HT_HG-U133A	PTH1R ITPR2 TG SPTBN5 HEYL SYNJ2 MVP	9.94e-05	197	123	7	3063_UP
Drug	Glycopyrrolate [596-51-0]; Down 200; 10uM; HL60; HT_HG-U133A	ZNF444 MAP4 TOM1 SYNJ2 MRTFA DNMT3B SOS2	9.94e-05	197	123	7	2565_DN
Drug	Carbimazole [22232-54-8]; Up 200; 21.4uM; MCF7; HT_HG-U133A	COL5A1 MAP4 CENPO TESK1 KCNK5 MRTFA SOS2	1.03e-04	198	123	7	5399_UP
Drug	(cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; MCF7; HT_HG-U133A	RPH3A SH3D21 ITPR2 SPTBN5 SCN4A ZNF264 CCDC40	1.03e-04	198	123	7	4363_UP
Drug	LY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	DNAH3 MAP4 EPN2 ZNF512B INF2 BTBD7 MRTFA	1.03e-04	198	123	7	996_DN
Drug	Benperidol [2062-84-2]; Up 200; 10.4uM; PC3; HT_HG-U133A	HDAC6 DISC1 ITPR2 PLEKHG3 AHNAK HBB DOP1A	1.03e-04	198	123	7	4196_UP
Drug	Mafenide hydrochloride [138-37-4]; Up 200; 18uM; MCF7; HT_HG-U133A	TBX3 MAP4 ADAM20 NCAM1 SYNJ2 HBB MRTFA	1.06e-04	199	123	7	2287_UP
Drug	aspirin, USP; Up 200; 100uM; HL60; HT_HG-U133A	NPTX2 SH3D21 ITPR2 SCN4A PCDH1 CCDC40 ZNF646	1.06e-04	199	123	7	6164_UP
Drug	Leucomisine [17946-87-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A	COL15A1 DISC1 CUBN RPH3A MAGI2 SCN4A MRTFA	1.06e-04	199	123	7	3546_UP
Drug	Amiprilose hydrochloride [60414-06-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A	TBX3 CEL DISC1 TOM1 MAGI2 PLEKHG3 BTBD7	1.06e-04	199	123	7	4119_DN
Drug	Iopromide [73334-07-3]; Down 200; 5uM; MCF7; HT_HG-U133A	DNAH3 ZNF444 BAZ2B DISC1 TOM1 TESK1 ITPR2	1.06e-04	199	123	7	3481_DN
Drug	Canavanine sulfate monohydrate (L,+) [206996-57-8]; Up 200; 13.6uM; PC3; HT_HG-U133A	ZNF536 EXO5 HTR3A DISC1 ITPR2 AHNAK PCDH1	1.06e-04	199	123	7	4197_UP
Drug	Tetracycline hydrochloride [64-75-5]; Up 200; 8.4uM; HL60; HG-U133A	CEL EBLN2 TOM1 CUBN TESK1 ZNF512B SOS2	1.09e-04	200	123	7	1397_UP
Drug	Sulfathiazole [72-14-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A	TBX3 NCAM1 SPTBN5 SYNJ2 HBB MVP SOS2	1.09e-04	200	123	7	4769_UP
Drug	Carteolol hydrochloride [51781-21-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A	MAP4 DISC1 TOM1 ITPR2 BTBD7 MVP MRTFA	1.09e-04	200	123	7	3276_DN
Drug	HPED	HBB HBD	1.72e-04	4	123	2	CID000125856
Drug	4-(2-carboxyvinyl)benzoic acid	HBB HBD	1.72e-04	4	123	2	CID000089196
Drug	1,4-dibromobenzene	HBB HBD	1.72e-04	4	123	2	CID000007804
Drug	AC1L4CDO	HBB HBD	1.72e-04	4	123	2	CID000154482
Drug	AF-30	HTR3A PAF1	1.72e-04	4	123	2	CID000129993
Drug	PTU-23	HBB HBD	1.72e-04	4	123	2	CID000853760
Drug	AC1L9JVG	HBB HBD	1.72e-04	4	123	2	CID000446603
Drug	1,2,4,5-tetrabromobenzene	HBB HBD	1.72e-04	4	123	2	CID000012486
Drug	AC1NBUB1	CEL CHD4 KDM5D	1.91e-04	21	123	3	CID004473866
Disease	Delta-Beta Thalassemia	HBB HBD	4.83e-05	3	119	2	C0271985
Disease	developmental and epileptic encephalopathy 33 (implicated_via_orthology)	EEF1A1 EEF1A1P5	4.83e-05	3	119	2	DOID:0080463 (implicated_via_orthology)
Disease	beta thalassemia (implicated_via_orthology)	HBB HBD	4.83e-05	3	119	2	DOID:12241 (implicated_via_orthology)
Disease	irritable bowel syndrome, anorexia nervosa	NCAM1 FAM120A	4.83e-05	3	119	2	EFO_0000555, MONDO_0005351
Disease	urate measurement	DNAH3 TPCN2 MAP4 NSD1 CUBN RPH3A PTH1R TBC1D10A RNASEH2C KCNK5 MYO18B HBB SOS2	6.81e-05	895	119	13	EFO_0004531
Disease	hemoglobin measurement, hemoglobin A2 measurement	HBD HBD	1.60e-04	5	119	2	EFO_0004509, EFO_0005845
Disease	necrotizing enterocolitis	TCF20 MCTP1 MACROD2	1.74e-04	27	119	3	EFO_0003928
Disease	bipolar disorder (is_implicated_in)	IMPA2 DISC1 NCAM1	2.16e-04	29	119	3	DOID:3312 (is_implicated_in)
Disease	hemoglobin E disease	HBD HBD	2.39e-04	6	119	2	MONDO_0016243
Disease	Chloracne	AHNAK HBB HBD	3.19e-04	33	119	3	C0263454
Disease	anemia (biomarker_via_orthology)	HBB HBD	3.34e-04	7	119	2	DOID:2355 (biomarker_via_orthology)
Disease	Mood Disorders	IMPA2 HTR3A DISC1 NCAM1 DNMT3B	6.10e-04	168	119	5	C0525045
Disease	cognitive function measurement	COL5A1 ZNF536 ANKFY1 TCF20 CEL MAP4 NCAM1 RGS3 KMT2D FAM120A TMEM245 MACROD2 MYO18B PCDH1 MRTFA	6.64e-04	1434	119	15	EFO_0008354
Disease	Autistic Disorder	HTR3A DISC1 NSD1 CHD4 WDFY4 MACROD2	6.82e-04	261	119	6	C0004352
Disease	Anxiety States, Neurotic	DISC1 TG MAGI2	7.51e-04	44	119	3	C0376280
Disease	schizophrenia (is_marker_for)	DISC1 NCAM1 CALY	7.51e-04	44	119	3	DOID:5419 (is_marker_for)
Disease	Anxiety neurosis (finding)	DISC1 TG MAGI2	7.51e-04	44	119	3	C1279420
Disease	Anxiety Disorders	DISC1 TG MAGI2	7.51e-04	44	119	3	C0003469
Disease	early infantile epileptic encephalopathy (implicated_via_orthology)	IDH3A STXBP1	8.66e-04	11	119	2	DOID:0050709 (implicated_via_orthology)
Disease	pathological myopia	ZNF536 TACC2 CHD4 PCDH1	1.08e-03	111	119	4	EFO_0004207
Disease	Depressive disorder	HDAC6 IMPA2 HTR3A DISC1 NCAM1 TG	1.15e-03	289	119	6	C0011581
Disease	peripheral arterial disease, traffic air pollution measurement	IMPA2 ITPR2 MCTP1 MACROD2 NAV2	1.16e-03	194	119	5	EFO_0004265, EFO_0007908
Disease	trimethylamine-N-oxide measurement	CUBN ITPR2	1.42e-03	14	119	2	EFO_0010541
Disease	comparative body size at age 10, self-reported	ZNF536 MAGI2 STXBP1 FAM120A BTBD7 MACROD2 SIPA1L2	1.61e-03	420	119	7	EFO_0009819
Disease	Down syndrome (implicated_via_orthology)	SYNJ2 DOP1A	1.64e-03	15	119	2	DOID:14250 (implicated_via_orthology)
Disease	Yu-Zhi constitution type	RRN3P2 MACROD2	1.64e-03	15	119	2	EFO_0007638
Disease	MAJOR AFFECTIVE DISORDER 2	TOM1 MAGI2	2.11e-03	17	119	2	C1839839
Disease	cannabis dependence	TCF20 NCAM1 MAGI2 TMEM245	2.22e-03	135	119	4	EFO_0007191
Disease	Tourette syndrome, schizophrenia	ZNF536 TCF20	2.37e-03	18	119	2	EFO_0004895, MONDO_0005090
Disease	Schizophrenia	IMPA2 HTR3A DISC1 NCAM1 CHD4 MAGI2 STXBP1 TMEM245 CALY DNMT3B	3.10e-03	883	119	10	C0036341
Disease	obsolete_red blood cell distribution width	ABL1 CEL C3orf62 BAZ2B CENPO HBD CHD4 EEF1A1 EEF1A1P5 RNASEH2C RP1L1 HBB HBD	3.10e-03	1347	119	13	EFO_0005192
Disease	type 1 diabetes mellitus (is_marker_for)	CEL NCAM1 DNMT3B	3.11e-03	72	119	3	DOID:9744 (is_marker_for)
Disease	uric acid measurement	DNAH3 CEL CUBN RPH3A HSF5 RNASEH2C KCNK5 SOS2	3.36e-03	610	119	8	EFO_0004761
Disease	hair colour measurement	FLII TPCN2 TOM1 RGS3 MSX2 KMT2D AHNAK SIPA1L2	3.53e-03	615	119	8	EFO_0007822
Disease	Mental Depression	HDAC6 IMPA2 HTR3A DISC1 NCAM1	3.74e-03	254	119	5	C0011570
Disease	schizophrenia (is_implicated_in)	IMPA2 DISC1 DNMT3B	3.90e-03	78	119	3	DOID:5419 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
PIPDMSGKESGADGA	TADA3	281	O75528
KAPPNEMGSDAENEA	ERICH3	1116	Q5RHP9
TTPNHDPMAGGDKDD	AMIGO1	421	Q86WK6
GEDGDGSDTPVMPKL	DNMT3B	76	Q9UBC3
SADSGPPPKNNMEGL	ADAM20	671	O43506
ESEVMTPKPNAGANG	BAZ2B	1481	Q9UIF8
SHMGGPQDFEKSPRD	HTR3A	386	P46098
EGPEVDMNLPKADLG	AHNAK	1526	Q09666
MEQPKDGAGPEGNNL	C19orf84	1	I3L1E1
ESDMGSPGSRKSPNF	DOP1A	1346	Q5JWR5
EGKVAGPADAPMDSG	DOT1L	361	Q8TEK3
FAKTGDPNMGDSAVP	CEL	491	P19835
SPQEMGAKAASLDGP	DISC1	241	Q9NRI5
SPHMEQSSLDPGKEG	MSANTD2	436	Q6P1R3
GAEDPSKEDPLQIMG	NSD1	1081	Q96L73
MAEDEPDAKSPKTGG	RFX5	1	P48382
MALEEGKGPGAEDSP	RGS3	691	P49796
LLQQMLKPGSDPDEG	ITPR2	2121	Q14571
CSSDKMGPEAAPAAT	ZFYVE28	691	Q9HCC9
ENPTEPGSDGTMSDK	APLP2	286	Q06481
TRGADMSVPDEKGNP	ANKFY1	676	Q9P2R3
VNMPGPSSESLGKDD	EXO5	41	Q9H790
GEGLPKTDLMAFSPS	PCDHA3	761	Q9Y5H8
AAAAAAGSGPKDPMA	FLII	411	Q13045
AGTSNAEVPLADPGM	MCTP1	246	Q6DN14
AGQNDPLKDSYGMSP	MAP4	166	P27816
IPDGPAAQDGKMETG	MAGI2	456	Q86UL8
DLMDALPSSGPAAQK	EPN2	336	O95208
GDSVTSPENMAPGKG	KDM5D	1341	Q9BY66
SPENMAPGKGSDLEL	KDM5D	1346	Q9BY66
ASPDAMEVGKGASPF	ECE2	36	P0DPD6
MAAPEGKRSLANGPN	EID1	66	Q9Y6B2
QGAEAKAPLNMGEFP	KCNK5	451	O95279
SLKFNLMSDAPGDSP	PCDH1	936	Q08174
LRKDSQPSSPGDDAM	EBLN2	51	Q6P2I7
MKRPKEPSGSDGESD	HEYL	1	Q9NQ87
AEEKPAPQMNGSTGD	FAM120A	1056	Q9NZB2
EETKTACLGDPGSPM	PRSS54	211	Q6PEW0
MKPSGEDQAALAAGP	IMPA2	1	O14732
TDGGSKAASMDPPRA	INF2	996	Q27J81
FETSEAKGPDGMALP	MVP	606	Q14764
DPAPKDTSGAAALEM	PAF1	226	Q8N7H5
DGGKAAASGQPRPEM	OTULIN	31	Q96BN8
GDEKPPLIRSSGDSM	CUBN	1241	O60494
GTAPDIAGKDMANPT	IDH3A	291	P50213
PMLEKDAAGGDFPAN	IGSF23	26	A1L1A6
SDGLGIKMPDPDFTV	KDM2A	81	Q9Y2K7
PGDQDGAAMDSVPLI	CALY	16	Q9NYX4
SPSADPMAGLLKFAD	DNAH3	3526	Q8TD57
AGDSKNDPPMEAAGF	EEF1A1	326	P68104
MDKSPQKATDADPGS	C3orf62	221	Q6ZUJ4
GEKEGNNESHMVSPP	CCDC40	21	Q4G0X9
MASPGKPGADEAQEE	CRACR2B	1	Q8N4Y2
DVPEMPHSKGQGESD	ABL1	546	P00519
EAAPMPETSEGAGKE	COL5A1	316	P20908
PSDMLPTTEGGKSNA	BTBD7	546	Q9P203
AATGSPSADKDGMEP	C3orf33	6	Q6P1S2
AGDSKNDPPMEAAGF	EEF1A1P5	326	Q5VTE0
MEQANPLRPDGESKG	CENPO	1	Q9BU64
FGDLSSPDAVMGNPK	HBD	46	P02042
FGDLSTPDAVMGNPK	HBB	46	P68871
SEGTMPPNKEASGLS	HOMEZ	21	Q8IX15
ANPVGPSGGMSDDDK	COG2	676	Q14746
DALQGDPKGEMAATP	HDAC6	346	Q9UBN7
DPKGEMAATPAGFAQ	HDAC6	351	Q9UBN7
RKNDMDEPPSGDFGG	CHD4	576	Q14839
EKGDINGSFLMSGPP	COL15A1	1041	P39059
MPGKQSEEGPAEAGA	SBK2	1	P0C263
SGKATEGPFAMDPDS	CDH16	61	O75309
FHGMEKSLEPEESPG	PHF20	476	Q9BVI0
MASPSKGNDLFSPDE	MSX2	1	P35548
PRMPGKSEGSSDLEN	MACROD2	391	A1Z1Q3
PLKMSSNGCENDPGD	SYDE2	921	Q5VT97
GFLISEMGPASKPSE	HSF5	536	Q4G112
EMGPASKPSEDTGLA	HSF5	541	Q4G112
TARDQDLEPGAPSMG	EPRS1	1461	P07814
DLEPGAPSMGAKSLC	EPRS1	1466	P07814
AKGLKPMDSNGLADP	RPH3A	416	Q9Y2J0
NSKGNMKSDDDPPAI	SOS2	1161	Q07890
PSMAAAAGPLDGKVA	TBX3	661	O15119
SPEEKGEAGDAGPTM	SCN4A	1791	P35499
NDKGGLGNPDMPSVS	SH3D21	26	A4FU49
SPDSDGTKAMKPEAA	SYNJ2	1391	O15056
MTFALPEGPLGNEKE	NBR1	676	Q14596
MEEPSSSEAPAKNGA	PLEKHG3	36	A1L390
GSTSKQMPPSDAEGD	NAV2	2431	Q8IVL1
PLCVDPGSGKEFMDT	SIPA1L2	1631	Q9P2F8
AMEGPSNPGDNKELK	SHROOM4	741	Q9ULL8
GATGKDTMGDLPRDP	NPTX2	106	P47972
SPDPGNAKGKDAIME	STXBP3	161	O00186
DPTMGEGPDKARSQL	STXBP1	216	P61764
LTGKPGALPANLDDM	MRTFA	336	Q969V6
DPQDAKGTPTMEGSL	SPTBN5	3526	Q9NRC6
EPSAPKLEGQMGEDG	NCAM1	611	P13591
GKEDSGMIPLAGTAP	ZNF444	126	Q8N0Y2
GASENLENPPKMGEE	SEC16A	786	O15027
TPAQSGPLVAGDDMK	RP1L1	296	Q8IWN7
NPEMSGGGAPAEETK	SMTNL1	21	A8MU46
TPPAMAAPKDDGFLN	PTH1R	551	Q03431
DLIDMGPDPAATGNL	TOM1	321	O60784
ESIKDSSMGGQEEPP	ARHGAP28	86	Q9P2N2
DAAMFRDGKEPQPSA	WDFY4	1936	Q6ZS81
ADKAPSPLGVAGDAM	ZNF646	986	O15015
VSMGKPDPLRDSGTD	RNASEH2C	91	Q8TDP1
GEDMQPKDPAALGSS	nan	221	A8MX80
AKSPMFPALGEASSD	WASHC2C	1146	Q9Y4E1
SKREMASGNTGEAPP	TACC2	1031	O95359
GPSAEEKMECEGSSP	TESK1	461	Q15569
PGDAAASPSAVKMLG	RRN3P2	11	A6NIE6
ATSPGAKDMPLSSDG	TCF20	581	Q9UGU0
GKESEGSRSPDPEQM	MYO18B	106	Q8IUG5
MEEEASSPGLGCSKP	TPGS2	1	Q68CL5
SGFMTPDKAGLSEPS	ZNF536	436	O15090
GEDMQPKDPAVLGSS	nan	191	A8MV72
PGKMSPECDGLGTAD	ZNF264	151	O43296
SGGMEALKAAGPASP	ZNF512B	396	Q96KM6
MADGGGPKDAPSLRS	TMEM245	1	Q9H330
SGPPMDISNKASGEI	TM9SF2	251	Q99805
GEDMQPKDPAALGSS	nan	221	Q8N9G6
GEDMQPKDPAALGSS	nan	221	A8MUI8
GEDMQPKDPAALGSS	nan	221	A8MUA0
MAKSNGENGPRAPAA	TBC1D10A	1	Q9BXI6
GDKSPPQCSAEGEFM	TG	176	P01266
MGDAGSERSKAPSLP	ZFAND3	1	Q9H8U3
MGPESQSPDCKDGAA	SAMD4A	441	Q9UPU9
ISMDDFTPPGSGACK	THAP4	216	Q8WY91
MAEPQAESEPLLGGA	TPCN2	1	Q8NHX9
PQTMLGEDSAPGNGK	VWA5B1	946	Q5TIE3
MAEKEGPGDPSSDLK	ZFP69	136	Q49AA0
DMAPASTAEGAGEKP	ZNF628	11	Q5EBL2
PGSNEDTDIPKGYMD	TXNL1	111	O43396
EKPGTPGEGMLSSDL	KMT2D	1861	O14686
LVGPEEKMGLPGSDS	KIAA1522	1016	Q9P206