Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	KIF21B DYNC2H1 KIF21A FIGNL2 KIF4A ABCC9 UBA3 BTAF1 MSH2 FIGN ATP13A2 MYH14 MYO3B RECQL5 KIF4B DDX20 ATP2B1 ATP2B2 ABCC10 AQR KIF25	4.73e-08	614	167	21	GO:0140657
GeneOntologyMolecularFunction	ATP hydrolysis activity	KIF21B DYNC2H1 KIF21A FIGNL2 ABCC9 BTAF1 MSH2 FIGN ATP13A2 RECQL5 DDX20 ATP2B1 ATP2B2 ABCC10 AQR KIF25	9.65e-07	441	167	16	GO:0016887
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF21B DYNC2H1 KIF21A KIF4A MYH14 MYO3B KIF4B KIF25	6.78e-06	118	167	8	GO:0003774
GeneOntologyMolecularFunction	microtubule motor activity	KIF21B DYNC2H1 KIF21A KIF4A KIF4B KIF25	2.63e-05	70	167	6	GO:0003777
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	KIF21B DYNC2H1 KIF21A FIGNL2 ABCC9 BTAF1 MSH2 FIGN ATP13A2 RECQL5 RAB2B DDX20 RAB2A ATP2B1 ATP2B2 ABCC10 AQR KIF25	8.98e-05	775	167	18	GO:0017111
GeneOntologyMolecularFunction	pyrophosphatase activity	KIF21B DYNC2H1 KIF21A FIGNL2 ABCC9 BTAF1 MSH2 FIGN ATP13A2 RECQL5 RAB2B DDX20 RAB2A ATP2B1 ATP2B2 ABCC10 AQR KIF25	2.40e-04	839	167	18	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	KIF21B DYNC2H1 KIF21A FIGNL2 ABCC9 BTAF1 MSH2 FIGN ATP13A2 RECQL5 RAB2B DDX20 RAB2A ATP2B1 ATP2B2 ABCC10 AQR KIF25	2.43e-04	840	167	18	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	KIF21B DYNC2H1 KIF21A FIGNL2 ABCC9 BTAF1 MSH2 FIGN ATP13A2 RECQL5 RAB2B DDX20 RAB2A ATP2B1 ATP2B2 ABCC10 AQR KIF25	2.43e-04	840	167	18	GO:0016818
GeneOntologyBiologicalProcess	Golgi organization	DYNC2H1 SYNE1 OBSL1 CUL7 TRIP11 HACE1 RAB2B RAB2A CAMSAP2	1.04e-05	168	169	9	GO:0007030
HumanPheno	Hypoplastic ischia	OBSL1 ABCC9 CUL7 TRIP11	1.07e-05	16	47	4	HP:0003175
Domain	LRR_6	TCTE1 NLRP12 LRRC34 AMN1 CARMIL1 NLRX1 FBXL14 RNH1 CEP78	1.39e-09	55	168	9	PF13516
Domain	-	TCTE1 KCTD9 NLRP12 LRRC34 AMN1 PRAMEF19 CARMIL1 NLRX1 LRSAM1 FBXL14 PRAMEF17 ELFN2 AMIGO3 RNH1 CEP78 CD180	3.49e-08	321	168	16	3.80.10.10
Domain	L_dom-like	TCTE1 KCTD9 NLRP12 LRRC34 AMN1 PRAMEF19 CARMIL1 NLRX1 LRSAM1 FBXL14 PRAMEF17 ELFN2 AMIGO3 RNH1 CEP78 CD180	4.70e-08	328	168	16	IPR032675
Domain	Leu-rich_rpt	TCTE1 NLRP12 LRRC34 AMN1 CARMIL1 NLRX1 LRSAM1 FBXL14 ELFN2 AMIGO3 RNH1 CEP78 CD180	1.09e-06	271	168	13	IPR001611
Domain	P-loop_NTPase	KIF21B NLRP12 DYNC2H1 KIF21A FIGNL2 KIF4A ABCC9 BTAF1 MSH2 SLFN5 GAL3ST2 FIGN MYH14 MYO3B RECQL5 RAB2B AK2 KIF4B DDX20 RAB2A ABCC10 AQR KIF25	2.26e-06	848	168	23	IPR027417
Domain	Kinesin_motor_CS	KIF21B KIF21A KIF4A KIF4B KIF25	3.20e-05	41	168	5	IPR019821
Domain	Kinesin-like_fam	KIF21B KIF21A KIF4A KIF4B KIF25	4.05e-05	43	168	5	IPR027640
Domain	-	KIF21B KIF21A KIF4A KIF4B KIF25	4.54e-05	44	168	5	3.40.850.10
Domain	Kinesin	KIF21B KIF21A KIF4A KIF4B KIF25	4.54e-05	44	168	5	PF00225
Domain	KISc	KIF21B KIF21A KIF4A KIF4B KIF25	4.54e-05	44	168	5	SM00129
Domain	KINESIN_MOTOR_1	KIF21B KIF21A KIF4A KIF4B KIF25	4.54e-05	44	168	5	PS00411
Domain	Kinesin_motor_dom	KIF21B KIF21A KIF4A KIF4B KIF25	4.54e-05	44	168	5	IPR001752
Domain	KINESIN_MOTOR_2	KIF21B KIF21A KIF4A KIF4B KIF25	4.54e-05	44	168	5	PS50067
Domain	C8	MUC19 FCGBP OTOG	1.48e-04	12	168	3	PF08742
Domain	TIL	MUC19 FCGBP OTOG	1.48e-04	12	168	3	PF01826
Domain	Unchr_dom_Cys-rich	MUC19 FCGBP OTOG	1.91e-04	13	168	3	IPR014853
Domain	C8	MUC19 FCGBP OTOG	1.91e-04	13	168	3	SM00832
Domain	TIL_dom	MUC19 FCGBP OTOG	2.42e-04	14	168	3	IPR002919
Domain	VWF_type-D	MUC19 FCGBP OTOG	3.67e-04	16	168	3	IPR001846
Domain	VWFD	MUC19 FCGBP OTOG	3.67e-04	16	168	3	PS51233
Domain	VWD	MUC19 FCGBP OTOG	3.67e-04	16	168	3	SM00216
Domain	VWD	MUC19 FCGBP OTOG	3.67e-04	16	168	3	PF00094
Domain	ATP_Ca_trans_C	ATP2B1 ATP2B2	4.77e-04	4	168	2	IPR022141
Domain	5peptide_repeat	KCTD9 SV2C	4.77e-04	4	168	2	IPR001646
Domain	ATP_Ca_trans_C	ATP2B1 ATP2B2	4.77e-04	4	168	2	PF12424
Domain	P-type_ATPase_IIB	ATP2B1 ATP2B2	4.77e-04	4	168	2	IPR006408
Domain	Cation_ATPase_N	ATP13A2 ATP2B1 ATP2B2	5.28e-04	18	168	3	SM00831
Domain	Leu-rich_rpt_Cys-con_subtyp	AMN1 FBXL14 RNH1	6.23e-04	19	168	3	IPR006553
Domain	LRR_CC	AMN1 FBXL14 RNH1	6.23e-04	19	168	3	SM00367
Domain	VWC_out	MUC19 FCGBP OTOG	6.23e-04	19	168	3	SM00215
Domain	ATPase_P-typ_cation-transptr_N	ATP13A2 ATP2B1 ATP2B2	6.23e-04	19	168	3	IPR004014
Pathway	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	TPP2 CUL1 TRIM73 PSMA4 LRSAM1 FBXL14 UBA3 UFL1 MIB2 CUL7 HACE1 TRIM50 TRIM74	2.48e-06	299	125	13	MM15711
Pathway	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	TPP2 CUL1 TRIM73 PSMA4 LRSAM1 FBXL14 UBA3 UFL1 MIB2 CUL7 HACE1 TRIM50 TRIM74	1.10e-05	343	125	13	MM15712
Pathway	REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	TPP2 CUL1 PSMA4 LRSAM1 FBXL14 UBA3 UFL1 MIB2 CUL7 HACE1 TRIM50	9.20e-05	308	125	11	M1070
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	CUL1 CAD NRDC DYNC2H1 SYNE1 PSMA4 ANXA6 UFL1 MSH2 NEK9 TOE1 SART1 GTF3C2 CLCA2 XPO5 MYH14 CTR9 SF3A3 UTP20 DDX20 RAB2A ATP2B1 AQR EPB41L2 PCYOX1	3.63e-08	1425	171	25	30948266
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CUL1 CAD KIF21A PSMA4 TAF1C LRSAM1 KIF4A MSH2 NEK9 TOE1 SART1 GTF3C2 RNH1 MYH14 CTR9 RECQL5 SF3A3 ANKRD28 UTP20 POLR1B DDX20 ATP2B1 AQR EPB41L2	5.72e-08	1353	171	24	29467282
Pubmed	Gene structure variation in segmental duplication block C of human chromosome 7q 11.23 during primate evolution.	TRIM73 TRIM50 TRIM74	1.17e-07	3	171	3	26196062
Pubmed	TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells.	TRIM73 TRIM50 TRIM74	1.17e-07	3	171	3	22872646
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	TPP2 CUL1 CACNA1S NRDC KIF21A PSMA4 ANXA6 LRSAM1 APEH UBA3 MSH2 ARFIP2 POLA2 RUFY1 NEK9 RNH1 PDLIM1 XPO5 MYH14 CTR9 SF3A3 ANKRD28 LIMCH1 EPB41L2	2.17e-07	1455	171	24	22863883
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TPP2 CAD ANXA6 KIF4A MSH2 CUL7 SART1 RNH1 XPO5 MYH14 ANKRD28 UTP20 DDX20 AQR EPB41L2	9.28e-07	653	171	15	22586326
Pubmed	All kinesin superfamily protein, KIF, genes in mouse and human.	KIF21B KIF21A KIF4A KIF4B KIF25	1.04e-06	37	171	5	11416179
Pubmed	Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice.	TRIM73 TRIM50 TRIM74	1.16e-06	5	171	3	20049703
Pubmed	Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase.	TRIM73 TRIM50 TRIM74	1.16e-06	5	171	3	18398435
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	KIF21B TPP2 KCTD9 CAD SYNE1 KIF21A ZBTB22 KCNAB2 KIF4A TRIP11 NEK9 SART1 ANKRD28 KIF4B LIMCH1 RAB2A CAMSAP2 EPB41L2	1.42e-06	963	171	18	28671696
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CUL1 CAD DYNC2H1 LRSAM1 OBSL1 CEP192 CUL7 RUFY1 TRIP11 RIMBP3 ARFGEF3 CTR9 RECQL5 DDX20	1.43e-06	588	171	14	38580884
Pubmed	TRIM50 regulates Beclin 1 proautophagic activity.	TRIM73 TRIM50 TRIM74	2.31e-06	6	171	3	29604308
Pubmed	TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.	TRIM73 TRIM50 TRIM74	2.31e-06	6	171	3	36178239
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	DYNC2H1 CARMIL1 TTC21A OBSL1 MSH2 TRIP11 NEK9 SART1 TLK1 GTF3C2 RNH1 PDLIM1 XPO5 CTR9 SF3A3 ANKRD28 DDX20 PAN3 RAB2A CAMSAP2 ATP2B2	2.38e-06	1321	171	21	27173435
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	CUL1 NRDC DYNC2H1 PSMA4 TAF1C UBA3 ICE1 MSH2 CEP192 POLA2 SART1 RNH1 IFRD2 SF3A3 ANKRD28 POLR1B PAN3 AQR	2.58e-06	1005	171	18	19615732
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CAD KRT82 SYNE1 ANXA6 OBSL1 UFL1 BTAF1 MSH2 CUL7 SART1 AARS2 PDLIM1 MYH14 SF3A3 UTP20 ATP2B1 AQR EPB41L2	3.35e-06	1024	171	18	24711643
Pubmed	Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.	TRIM73 TRIM50 TRIM74	4.03e-06	7	171	3	26025256
Pubmed	Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.	CUL1 PSMA4 MSH2 RNH1 ANKRD28 DDX20	4.10e-06	85	171	6	19596235
Pubmed	Molecular cloning and characterization of a novel human Rab ( Rab2B) gene.	RAB2B RAB2A	2.40e-05	2	171	2	12376746
Pubmed	KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.	KIF4A KIF4B	2.40e-05	2	171	2	36482480
Pubmed	Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B.	KIF21B KIF21A	2.40e-05	2	171	2	10225949
Pubmed	Natural history of facial and skeletal features from neonatal period to adulthood in a 3M syndrome cohort with biallelic CUL7 or OBSL1 variants.	OBSL1 CUL7	2.40e-05	2	171	2	34597859
Pubmed	Promoter methylation status of MGMT, hMSH2, and hMLH1 and its relationship to corresponding protein expression and TP53 mutations in human esophageal squamous cell carcinoma.	MSH2 MGMT	2.40e-05	2	171	2	24366688
Pubmed	The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential.	KIF4A KIF4B	2.40e-05	2	171	2	30081192
Pubmed	Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.	KIF4A KIF4B	2.40e-05	2	171	2	31067151
Pubmed	α-2,8-Sialyltransferase Is Involved in the Development of Multidrug Resistance via PI3K/Akt Pathway in Human Chronic Myeloid Leukemia.	ST8SIA6 ST8SIA4	2.40e-05	2	171	2	25855199
Pubmed	Lack of Annexin A6 Exacerbates Liver Dysfunction and Reduces Lifespan of Niemann-Pick Type C Protein-Deficient Mice.	NPC1 ANXA6	2.40e-05	2	171	2	33345999
Pubmed	Cellular motor protein KIF-4 associates with retroviral Gag.	KIF4A KIF4B	2.40e-05	2	171	2	10559369
Pubmed	Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy.	RAB2B RAB2A	2.40e-05	2	171	2	28063257
Pubmed	Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1.	SYNE1 CSMD1	2.40e-05	2	171	2	24387768
Pubmed	KIF4 regulates midzone length during cytokinesis.	KIF4A KIF4B	2.40e-05	2	171	2	21565503
Pubmed	Further expanding the mutational spectrum and investigation of genotype-phenotype correlation in 3M syndrome.	OBSL1 CUL7	2.40e-05	2	171	2	30980518
Pubmed	A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.	KIF4A KIF4B	2.40e-05	2	171	2	7929562
Pubmed	Coupling of vesicle tethering and Rab binding is required for in vivo functionality of the golgin GMAP-210.	TRIP11 RAB2A	2.40e-05	2	171	2	25473115
Pubmed	Selective Degradation Permits a Feedback Loop Controlling Annexin A6 and Cholesterol Levels in Endolysosomes of NPC1 Mutant Cells.	NPC1 ANXA6	2.40e-05	2	171	2	32392809
Pubmed	Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells.	KIF4A KIF4B	2.40e-05	2	171	2	31486502
Pubmed	Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization.	KIF4A KIF4B	2.40e-05	2	171	2	10773663
Pubmed	Missense Pathogenic variants in KIF4A Affect Dental Morphogenesis Resulting in X-linked Taurodontism, Microdontia and Dens-Invaginatus.	KIF4A KIF4B	2.40e-05	2	171	2	31616463
Pubmed	Kif4 regulates the expression of VEGFR1 through the PI3K/Akt signaling pathway in RAW264.7 monocytes/macrophages.	KIF4A KIF4B	2.40e-05	2	171	2	28350061
Pubmed	Epidermal growth factor and trefoil factor family 2 synergistically trigger chemotaxis on BEAS-2B cells via different signaling cascades.	TFF2 EGF	2.40e-05	2	171	2	15256384
Pubmed	Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts.	KIF4A KIF4B	2.40e-05	2	171	2	24658398
Pubmed	Structural basis for the ATP-induced isomerization of kinesin.	KIF4A KIF4B	2.40e-05	2	171	2	23500491
Pubmed	Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein.	KIF4A KIF4B	2.40e-05	2	171	2	9658142
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	CAD PSMA4 ANXA6 KIF4A UFL1 MSH2 ANKRD28 RAB2A ATP2B1 EPB41L2	3.09e-05	399	171	10	37536630
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SYNE1 OBSL1 CEP192 VAT1L ARFGEF3 XPO5 LIMCH1 CAMSAP2 AQR SENP7	3.66e-05	407	171	10	12693553
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	KIF21B CUL1 CARMIL1 LRSAM1 OBSCN RUFY1 TOE1 SART1 RPIA ANKRD28 LIMCH1	3.86e-05	497	171	11	36774506
Pubmed	Integral and associated lysosomal membrane proteins.	NPC1 ATP13A2 EGF CLCN6 RAB2A ABCC10	3.91e-05	126	171	6	17897319
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	CAD SYNE1 TAF1C KIF4A UFL1 ICE1 ANKZF1 LIN9 TOE1 GTF3C2 CTR9 RECQL5 IFRD2 UTP20 POLR1B DDX20 LIMCH1 CAMSAP2 AQR EPB41L2	5.09e-05	1497	171	20	31527615
Pubmed	The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.	TRIM73 TRIM50 TRIM74	6.24e-05	16	171	3	22792322
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	CAD ICE1 BTAF1 MSH2 XPO5 MYH14 UTP20	6.74e-05	202	171	7	33005030
Pubmed	Effect of DNA repair host factors on temozolomide or dacarbazine melanoma treatment in Caucasians.	MSH2 MGMT	7.19e-05	3	171	2	19741564
Pubmed	Expression of DNA repair proteins MSH2, MLH1 and MGMT in human benign and malignant thyroid lesions: an immunohistochemical study.	MSH2 MGMT	7.19e-05	3	171	2	21358597
Pubmed	PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex.	TAF1C POLR1B	7.19e-05	3	171	2	16055704
Pubmed	Tumor formation via loss of a molecular motor protein.	KIF4A KIF4B	7.19e-05	3	171	2	16890532
Pubmed	A rare cause of syndromic short stature: 3M syndrome in three families.	OBSL1 CUL7	7.19e-05	3	171	2	33258289
Pubmed	KIF4 mediates anterograde translocation and positioning of ribosomal constituents to axons.	KIF4A KIF4B	7.19e-05	3	171	2	19158085
Pubmed	Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex.	OBSCN OBSL1	7.19e-05	3	171	2	20133654
Pubmed	Identification of the human homologue of mouse KIF4, a kinesin superfamily motor protein.	KIF4A KIF4B	7.19e-05	3	171	2	10978527
Pubmed	Three M Syndrome	OBSL1 CUL7	7.19e-05	3	171	2	20301654
Pubmed	TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes.	TRPM5 CD180	7.19e-05	3	171	2	32521253
Pubmed	Trafficking of presynaptic PMCA signaling complexes in mouse photoreceptors requires Cav1.4 α1 subunits.	ATP2B1 ATP2B2	7.19e-05	3	171	2	22183401
Pubmed	Beyond the inflammasome: regulatory NOD-like receptor modulation of the host immune response following virus exposure.	NLRP12 NLRX1	7.19e-05	3	171	2	26763980
Pubmed	Protein kinase C phosphorylates the carboxyl terminus of the plasma membrane Ca(2+)-ATPase from human erythrocytes.	ATP2B1 ATP2B2	7.19e-05	3	171	2	1827443
Pubmed	Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions.	NPC1 ANXA6	7.19e-05	3	171	2	35022465
Pubmed	Plasma membrane Ca2+ ATPase isoform 2b interacts preferentially with Na+/H+ exchanger regulatory factor 2 in apical plasma membranes.	ATP2B1 ATP2B2	7.19e-05	3	171	2	11786550
Pubmed	Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.	OBSCN OBSL1	7.19e-05	3	171	2	27989621
Pubmed	The mouse fidgetin gene defines a new role for AAA family proteins in mammalian development.	FIGNL2 FIGN	7.19e-05	3	171	2	11017077
Pubmed	Promoter methylation status of hMLH1, hMSH2, and MGMT genes in colorectal cancer associated with adenoma-carcinoma sequence.	MSH2 MGMT	7.19e-05	3	171	2	21706233
Pubmed	Skeletal muscle delimited myopathy and verapamil toxicity in SUR2 mutant mouse models of AIMS.	CACNA1S ABCC9	7.19e-05	3	171	2	37154692
Pubmed	Plasma Membrane Calcium ATPase-Neuroplastin Complexes Are Selectively Stabilized in GM1-Containing Lipid Rafts.	ATP2B1 ATP2B2	7.19e-05	3	171	2	34948386
Pubmed	TNIP1/ANXA6 and CSMD1 variants interacting with cigarette smoking, alcohol intake affect risk of psoriasis.	ANXA6 CSMD1	7.19e-05	3	171	2	23541940
Pubmed	Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.	OBSCN OBSL1	7.19e-05	3	171	2	31098411
Pubmed	The genetics of 3-M syndrome: unravelling a potential new regulatory growth pathway.	OBSL1 CUL7	7.19e-05	3	171	2	22156540
Pubmed	Aberrant methylation of different DNA repair genes demonstrates distinct prognostic value for esophageal cancer.	MSH2 MGMT	7.19e-05	3	171	2	21674174
Pubmed	Interaction of AnxA6 with isolated and artificial lipid microdomains; importance of lipid composition and calcium content.	NPC1 ANXA6	7.19e-05	3	171	2	23360953
Pubmed	KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity.	KIF4A KIF4B	7.19e-05	3	171	2	16630823
Pubmed	Expression of DNA repair proteins, MSH2, MLH1 and MGMT in mobile tongue squamous cell carcinoma: associations with clinicopathological parameters and patients' survival.	MSH2 MGMT	7.19e-05	3	171	2	21029181
Pubmed	Exome sequencing identifies CCDC8 mutations in 3-M syndrome, suggesting that CCDC8 contributes in a pathway with CUL7 and OBSL1 to control human growth.	OBSL1 CUL7	7.19e-05	3	171	2	21737058
Pubmed	Mutations in CUL7, OBSL1 and CCDC8 in 3-M syndrome lead to disordered growth factor signalling.	OBSL1 CUL7	7.19e-05	3	171	2	23018678
Pubmed	CircKIF4A enhances osteosarcoma proliferation and metastasis by sponging MiR-515-5p and upregulating SLC7A11.	KIF4A KIF4B	7.19e-05	3	171	2	35579738
Pubmed	Mutation analysis of K-ras and beta-catenin genes related to O6-methylguanin-DNA methyltransferase and mismatch repair protein status in human gallbladder carcinoma.	MSH2 MGMT	7.19e-05	3	171	2	12469220
Pubmed	Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titin.	OBSCN OBSL1	7.19e-05	3	171	2	20489725
Pubmed	Whole exome sequencing identifies MAP3K1, MSH2, and MLH1 as potential cancer-predisposing genes in familial early-onset colorectal cancer.	MSH2 MAP3K1	7.19e-05	3	171	2	37314251
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	TPP2 CAD NRDC CARMIL1 KIF21A PSMA4 KIF4A UFL1 MSH2 ANKZF1 NEK9 TOE1 SART1 CTR9 SF3A3 AK2 DDX20 AQR EPB41L2	7.42e-05	1415	171	19	28515276
Pubmed	An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning.	CUL1 OBSL1 CUL7	7.55e-05	17	171	3	21572988
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	NPC1 TPP2 CAD NRDC P3H3 KIF21A PSMA4 APEH UFL1 POLA2 ANKZF1 PM20D2 SART1 XPO5 RAB2A AQR EPB41L2 PCYOX1	7.66e-05	1297	171	18	33545068
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	LRRC34 RASGRF1 ICE1 MIB2 SLFN5 SART1 ARFGEF3 SYCP2 ADAMTS18	8.07e-05	361	171	9	26167880
Pubmed	Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.	PSMA4 MSH2 NEK9 GTF3C2 RNH1 XPO5 DDX20	8.85e-05	211	171	7	17314511
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	TPP2 NRDC KIF4A CUL7 TRIP11 RPUSD4 RPIA	9.12e-05	212	171	7	33853758
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	CUL1 OBSL1 KIF4A UFL1 BTAF1 CUL7 LIN9 SART1 GTF3C2 AARS2 SF3A3 ANKRD28 UTP20 ATP2B1	9.39e-05	857	171	14	25609649
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	CUL1 NRDC POLA2 GTF3C2 AARS2 XPO5 CTR9 ANKRD28 AQR EPB41L2 PCYOX1	1.11e-04	560	171	11	35241646
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	CAD NRDC MSH2 SF3A3 ANKRD28 DDX20	1.15e-04	153	171	6	26365490
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TPP2 CUL1 CAD PSMA4 ANXA6 KCNAB2 APEH KIF4A MSH2 LIN9 SART1 TLK1 RNH1 XPO5 CTR9 RAB2A	1.18e-04	1103	171	16	34189442
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SYNE1 OBSL1 STAB1 TLK1 CLCN6 XPO5 ANKRD28	1.32e-04	225	171	7	12168954
Pubmed	Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.	ATP2B1 ATP2B2	1.43e-04	4	171	2	12209837
Pubmed	The E3 ubiquitin ligase SCFFBXL14 complex stimulates neuronal differentiation by targeting the Notch signaling factor HES1 for proteolysis.	CUL1 FBXL14	1.43e-04	4	171	2	29070679
Pubmed	Expression and role of calcium-ATPase pump and sodium-calcium exchanger in differentiated trophoblasts from human term placenta.	ATP2B1 ATP2B2	1.43e-04	4	171	2	12784250
Pubmed	FAM71F1 binds to RAB2A and RAB2B and is essential for acrosome formation and male fertility in mice.	RAB2B RAB2A	1.43e-04	4	171	2	34714330
Pubmed	The plasma membrane calcium pump in health and disease.	ATP2B1 ATP2B2	1.43e-04	4	171	2	23413890
Pubmed	PSD95beta regulates plasma membrane Ca2+ pump localization at the photoreceptor synapse.	ATP2B1 ATP2B2	1.43e-04	4	171	2	19233278
Cytoband	6p21.1	TCTE1 CUL7 AARS2 XPO5 ABCC10	1.30e-05	80	171	5	6p21.1
Cytoband	Ensembl 112 genes in cytogenetic band chr2p23	CAPN14 CAD TP53I3 RBKS GTF3C2	2.51e-04	149	171	5	chr2p23
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF21B KIF21A KIF4A KIF4B KIF25	1.11e-05	46	116	5	622
GeneFamily	Cullins	CUL1 CUL7	1.11e-03	8	116	2	1032
GeneFamily	ATPases Ca2+ transporting	ATP2B1 ATP2B2	1.43e-03	9	116	2	1209
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	MFSD4A HUNK PLEKHG4B ARFGEF3 SYCP2 FCGBP CLCA2 CNTN3	4.75e-07	179	171	8	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1S KRT82 MFSD4A RPIA ST8SIA6 POLI ANO7	3.70e-06	166	171	7	139bf49eb3624d9eec7e8a2cb33d69716d63a7c5
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-plasma_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1S KRT82 MFSD4A RPIA ST8SIA6 POLI ANO7	3.70e-06	166	171	7	85f59c3cc7db8863ec0044f1fcc14580834f830b
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2\|TCGA-Skin / Sample_Type by Project: Shred V9	NPC1 RASGRF1 KCNAB2 ST8SIA6 PLXNC1 FMN1 ANKRD28	6.53e-06	181	171	7	9d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRP2 OBSCN FIGN ARFGEF3 SYCP2 CSMD1 OTOG	7.27e-06	184	171	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRP2 OBSCN FIGN ARFGEF3 SYCP2 CSMD1 OTOG	7.27e-06	184	171	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRP2 OBSCN FIGN ARFGEF3 SYCP2 CSMD1 OTOG	7.27e-06	184	171	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MFSD4A VAT1L PLEKHG4B ARFGEF3 MYH14 CNTN3 LIMCH1	1.06e-05	195	171	7	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRR5L SYNE1 KIF21A ANXA6 MIB2 CEP78 SPON2	1.06e-05	195	171	7	14a6466524c22920daa622fbc710daf1defb46c3
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRR5L SYNE1 KIF21A ANXA6 MIB2 CEP78 SPON2	1.10e-05	196	171	7	bc4628d959d76c16981ac3b943f7c3fbbba49391
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRR5L SYNE1 KIF21A ANXA6 MIB2 CEP78 SPON2	1.13e-05	197	171	7	8e41e6cda38eace961cb1a56f4df24468c66b956
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRR5L SYNE1 KIF21A ANXA6 MIB2 CEP78 SPON2	1.13e-05	197	171	7	a44501cac24c2f4a53b413e92bd060eed6514616
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRR5L SYNE1 KIF21A ANXA6 MIB2 CEP78 SPON2	1.13e-05	197	171	7	2abe27f6722fa0dab801bca4cd19e34c1fb4173e
ToppCell	Sepsis-Leuk-UTI-Myeloid-cDC2\|Leuk-UTI / Disease, condition lineage and cell class	PSMA4 GIPR RNH1 PDLIM1 LIMCH1 CD180 EPB41L2	1.25e-05	200	171	7	1f1611c590230cd50b9bdca6b58291ab3aab85f2
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRR5L FIGNL2 OBSL1 FIGN SDR9C7 PLXNC1	2.42e-05	149	171	6	defe2e4a2f3118f8b42e99a4f2bf03e54c1b698f
ToppCell	RSV-Healthy-6\|Healthy / Virus stimulation, Condition and Cluster	TAF1C OBSCN WDR27 PM20D2 CLCN6 MYO3B	4.14e-05	164	171	6	1b9c5a6dc4e09b90f92e98b81a5ee620f8479cc7
ToppCell	RSV-Healthy-6\|RSV / Virus stimulation, Condition and Cluster	TAF1C OBSCN WDR27 PM20D2 CLCN6 MYO3B	4.14e-05	164	171	6	ab312b8c2f828ea7331f2a340c4df81587a23b5c
ToppCell	10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	NPTX1 CYP26A1 CC2D2B ZFYVE9 PLXNC1 KIF25	5.06e-05	170	171	6	97df5ffb328196c46568975d2d97722bcc753bf5
ToppCell	T_cells-GNLY+GZMB+_T_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	PRR5L SYNE1 CEP78 MYH14 SPON2 MYO3B	5.23e-05	171	171	6	04c811817cfec45af5f2891793106cc7ddb0300e
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MFSD4A FCGBP EGF FMN1 MYO3B TRIM50	5.58e-05	173	171	6	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	HUNK ARFGEF3 SYCP2 FCGBP CLCA2 CNTN3	5.76e-05	174	171	6	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CARMIL1 POLA2 ARFGEF3 XPO5 MYH14 ABCC10	5.94e-05	175	171	6	96219e58dcb327fd27190be78193e7a0d611e62b
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CARMIL1 POLA2 ARFGEF3 XPO5 MYH14 ABCC10	5.94e-05	175	171	6	cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRR5L NRDC SYNE1 ICE1 SLFN5 SPON2	6.33e-05	177	171	6	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRR5L NRDC SYNE1 ICE1 SLFN5 SPON2	6.33e-05	177	171	6	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	PRR5L NRDC SYNE1 ICE1 SLFN5 SPON2	6.33e-05	177	171	6	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	PRR5L NRDC SYNE1 ICE1 SLFN5 SPON2	6.33e-05	177	171	6	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PRR5L NRDC SYNE1 ICE1 SLFN5 SPON2	6.33e-05	177	171	6	d5aeda113afaa2425874394610344570c9078478
ToppCell	3'-Adult-Appendix-Epithelial-epithelial_progenitor_cell-Stem_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PSMA4 TAF1C RPIA HACE1 UTP20 DDX20	6.33e-05	177	171	6	34458f1eb7f3b1fd0cb9904529c01a9ca2f15500
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NPTX1 MFSD4A VAT1L ARFGEF3 MYH14 LIMCH1	6.53e-05	178	171	6	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A OBSL1 CLSTN2 ARFGEF3 MYH14 FMN1	6.73e-05	179	171	6	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MFSD4A VAT1L ARFGEF3 EGF FMN1 MYO3B	6.94e-05	180	171	6	9e09b3dfe344b5d50520711513d389865d73a861
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	RASGRF1 SYNE1 ABCC9 HUNK ARFGEF3 LIMCH1	6.94e-05	180	171	6	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MFSD4A VAT1L ARFGEF3 EGF FMN1 MYO3B	6.94e-05	180	171	6	a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HUNK PLEKHG4B ARFGEF3 FCGBP CLCA2 CNTN3	7.38e-05	182	171	6	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MFSD4A VAT1L ARFGEF3 EGF FMN1 MYO3B	7.38e-05	182	171	6	041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCell	Epithelial-lung_goblet_cell\|World / Lineage, Cell type, age group and donor	HUNK PLEKHG4B ARFGEF3 SYCP2 FCGBP CLCA2	7.61e-05	183	171	6	940cbe298e9c53b5622af09264586ed823d3141f
ToppCell	LPS_only-Epithelial_alveolar-AT_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A OBSL1 CLSTN2 ARFGEF3 MYH14 FMN1	7.61e-05	183	171	6	e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A OBSL1 CLSTN2 ARFGEF3 MYH14 FMN1	7.84e-05	184	171	6	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DRP2 P3H3 INHBA OBSL1 ABCC9 ARHGEF25	8.08e-05	185	171	6	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MFSD4A VAT1L ARFGEF3 EGF FMN1 MYO3B	8.08e-05	185	171	6	03f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MFSD4A VAT1L ARFGEF3 EGF FMN1 MYO3B	8.32e-05	186	171	6	1850583d23903d08226aeb0edb3e07b0994330e4
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	HUNK FIGN SLC35F4 FMN1 MYO3B ATP2B1	8.57e-05	187	171	6	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A CLSTN2 FIGN ARFGEF3 MYH14 FMN1	8.82e-05	188	171	6	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	MFSD4A VAT1L HUNK PLEKHG4B ARFGEF3 CNTN3	9.35e-05	190	171	6	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	AZIN2 TAF1C HPS3 IFRD2 UTP20 AQR	9.35e-05	190	171	6	2434b8ad2976eab7d9147012c28454ab29670709
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DYNC2H1 MFSD4A EGF FMN1 LIMCH1 TRIM50	9.35e-05	190	171	6	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CARMIL1 OBSL1 TRPM5 ADAMTS18 ANO7 CSMD1	9.63e-05	191	171	6	54f07e4de61735051498846afb44b1798bed8144
ToppCell	Leuk-UTI-Lymphocyte-T_NK-CD8_TEM\|Leuk-UTI / Disease, Lineage and Cell Type	SYNE1 KIF21A MIB2 SLFN5 CEP78 SPON2	9.91e-05	192	171	6	2787b52546eedada4aa413025b86841c351273f4
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMH+\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PRR5L SYNE1 KIF21A ANXA6 MIB2 CEP78	9.91e-05	192	171	6	01d01c9293f2439dc4c34c648273319c9beee5c7
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMH+-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PRR5L SYNE1 KIF21A ANXA6 MIB2 CEP78	9.91e-05	192	171	6	0f8c63de26128694f4522f9f6d029e4628c890bc
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	KIF21A TRIP11 ARFGEF3 CTR9 POLR1B AQR	1.02e-04	193	171	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	IIH-CD8\|IIH / Condition, Cell_class and T cell subcluster	PRR5L SYNE1 KIF21A MIB2 CEP78 PDLIM1	1.02e-04	193	171	6	343ac8c6dc6d7c7a944a14de65f1d4ea3dfafe86
ToppCell	IIH-CD8-CD8_1\|IIH / Condition, Cell_class and T cell subcluster	PRR5L SYNE1 KIF21A MIB2 CEP78 PDLIM1	1.02e-04	193	171	6	c5a4926003906d6726155f19061b73fb45d9962c
ToppCell	COVID-CD8-CD8_1\|COVID / Condition, Cell_class and T cell subcluster	PRR5L SYNE1 KIF21A ANXA6 MIB2 SLFN5	1.02e-04	193	171	6	221690901cb214c8ee186ff527c80dcc52d1fb1c
ToppCell	356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	PRR5L SYNE1 STAB1 FCGBP PLXNC1 ST8SIA4	1.05e-04	194	171	6	11ff53a748160570d2908ea9eb9779c038e5b676
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DYNC2H1 MFSD4A EGF FMN1 MYO3B TRIM50	1.08e-04	195	171	6	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NPTX1 CARMIL1 CLSTN2 CSMD1 ATP2B1 ATP2B2	1.08e-04	195	171	6	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	healthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	PRR5L SYNE1 KIF21A ANXA6 SLFN5 CEP78	1.11e-04	196	171	6	af00c31612e4fe068e5fccae05368edba46bbd20
ToppCell	Leuk-UTI-Myeloid-cDC2\|Leuk-UTI / Disease, Lineage and Cell Type	PSMA4 GIPR RNH1 LIMCH1 CD180 EPB41L2	1.11e-04	196	171	6	50465a082f03201936733c55af73bc32e1bdd024
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NLRP12 MAP3K1 STAB1 PLXNC1 FMN1 ST8SIA4	1.11e-04	196	171	6	cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRR5L SYNE1 KIF21A ANXA6 CEP78 SPON2	1.11e-04	196	171	6	51c750a0fb2b87e17e62b984c91fb16f676d7e76
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRR5L SYNE1 KIF21A SLFN5 CEP78 SPON2	1.11e-04	196	171	6	0f3c7fd450aaa1f866b8558692534c0ea2a34e75
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PRR5L SYNE1 KIF21A SLFN5 CEP78 SPON2	1.11e-04	196	171	6	4e1f8828413896ab8a4ec92a89d6789e8e37e05a
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PRR5L SYNE1 KIF21A SLFN5 CEP78 SPON2	1.14e-04	197	171	6	2b3a56bb1d40bc1284a5931c4e7b373660de5402
ToppCell	COVID-19_Severe-Lymphoid_T/NK-CD8+_Tem\|COVID-19_Severe / Disease group, lineage and cell class	PRR5L SYNE1 KIF21A SLFN5 CEP78 SPON2	1.14e-04	197	171	6	f0bac4d5c3160933ac3786cec8dadffb35d711ea
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	PRR5L SYNE1 KIF21A SLFN5 CEP78 SPON2	1.14e-04	197	171	6	836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PRR5L SYNE1 KIF21A SLFN5 CEP78 SPON2	1.14e-04	197	171	6	f73ece3aca28c0db5db0f12e026d42c6c36b9efb
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRR5L SYNE1 KIF21A ANXA6 CEP78 SPON2	1.14e-04	197	171	6	ff34be81ee77efe60618641fa7c1084442b991d7
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRR5L SYNE1 KIF21A SLFN5 CEP78 SPON2	1.14e-04	197	171	6	e70e7d97823a762def3970d94a0e897981a6c922
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2H1 SYNE1 TTC21A CLSTN2 PLEKHG4B GIPR	1.14e-04	197	171	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRR5L SYNE1 KIF21A SLFN5 CEP78 SPON2	1.14e-04	197	171	6	bce0135a96910d2bace62a3408a1a6fdac0cf0df
ToppCell	severe_COVID-19-CD4+_CTL\|severe_COVID-19 / disease group, cell group and cell class (v2)	PRR5L SYNE1 KIF21A SLFN5 CEP78 SPON2	1.14e-04	197	171	6	e51b7cd03b1450dc8601b4be0453b104d6a5f955
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRR5L SYNE1 KIF21A MIB2 CEP78 SPON2	1.14e-04	197	171	6	35004d4728d33f15cc3be99a073b1ea965365c32
ToppCell	T_cells-CTLs\|World / Immune cells in Kidney/Urine in Lupus Nephritis	PRR5L SYNE1 ANXA6 SLFN5 CEP78 SPON2	1.14e-04	197	171	6	2de34e20915a247bee75aa40495e23c20bb23e18
ToppCell	COVID_vent-Lymphocytic-T_cell-CD8+_Memory_T_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	PRR5L SYNE1 KIF21A SLFN5 CEP78 SPON2	1.14e-04	197	171	6	d4dfb3b561d0783cdbee4e8d27009ad81df695cb
ToppCell	(05)_Ciliated-(2)_48hpi\|(05)_Ciliated / shred by cell type and Timepoint	MIB2 ARHGEF25 ARFGEF3 SYCP2 OTOG	1.17e-04	124	171	5	fc8cce8c1809edafbc4e69e501dd4f016f5dfc0b
ToppCell	TCGA-Skin-Metastatic-Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	KIF21B ABCC9 MSH2 ST8SIA4 CD180 EPB41L2	1.17e-04	198	171	6	af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCell	healthy_donor-Lymphocytic-ILC-NK_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	PRR5L SYNE1 ANXA6 SLFN5 CEP78 SPON2	1.17e-04	198	171	6	d7053a898e04478c577381085f615edaad3cdc5b
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCTD9 CLSTN2 BDKRB2 PDLIM1 LIMCH1 EPB41L2	1.17e-04	198	171	6	447d7182edb2cd8a72ebd3c0d16bc6e4ddcaaa5c
ToppCell	mild-Lymphocytic-NK_cells\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PRR5L SYNE1 ANXA6 SLFN5 CEP78 SPON2	1.17e-04	198	171	6	dce3c008757786aa6bd4a869456b76b4cbbb1d5b
ToppCell	TCGA-Skin-Metastatic\|TCGA-Skin / Sample_Type by Project: Shred V9	KIF21B ABCC9 MSH2 ST8SIA4 CD180 EPB41L2	1.17e-04	198	171	6	ad39cce004867f083f8da1954e0cf5a263815184
ToppCell	severe_COVID-19-NK\|World / disease group, cell group and cell class (v2)	PRR5L SYNE1 SLFN5 ST8SIA6 CEP78 SPON2	1.17e-04	198	171	6	36b1370ef68c4bbe0268933a6ef5e6022d992bdf
ToppCell	healthy_donor-Lymphocytic-ILC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	PRR5L SYNE1 ANXA6 SLFN5 CEP78 SPON2	1.17e-04	198	171	6	aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	KIF21B ABCC9 MSH2 ST8SIA4 CD180 EPB41L2	1.17e-04	198	171	6	62cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCell	COVID-19-COVID-19_Severe-Others-HSPC\|COVID-19_Severe / Disease, condition lineage and cell class	OBSL1 FIGN ST8SIA6 ANKRD28 LIMCH1 CBX2	1.20e-04	199	171	6	25de67b6c9c8d6bb9a538e071a40ef865906c95d
ToppCell	Sepsis-Bac-SEP-Lymphocyte-T/NK-gd_T\|Bac-SEP / Disease, condition lineage and cell class	NPTX1 SYNE1 KIF21A ANXA6 SLFN5 SPON2	1.20e-04	199	171	6	29b2242be49a9640bfbae459edbfcc9f21d1a309
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD8+_Tem\|COVID-19_Severe / Disease, condition lineage and cell class	PRR5L SYNE1 KIF21A SLFN5 CEP78 SPON2	1.24e-04	200	171	6	31859b8db7ea17e48b7b54e92f0d76aeb755e7ca
ToppCell	mild-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NPC1 PRR5L SYNE1 KIF21A SLFN5 CEP78	1.24e-04	200	171	6	d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCell	Children_(3_yrs)-Immune-monocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NLRP12 MAP3K1 STAB1 PLXNC1 FMN1 ST8SIA4	1.24e-04	200	171	6	881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCell	severe-CD8+_Tem\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PRR5L SYNE1 KIF21A SLFN5 CEP78 SPON2	1.24e-04	200	171	6	aaa2cd326dc15dee2fd975ca133359c5826f6a75
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-NK\|Int-URO / Disease, condition lineage and cell class	SYNE1 ANXA6 MIB2 SLFN5 CEP78 SPON2	1.24e-04	200	171	6	3ae0f3dc4f6c9e0315155de80967134b2c1b3364
ToppCell	Neuronal-Excitatory\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NPTX1 CARMIL1 MFSD4A CLSTN2 ATP2B1 EPB41L2	1.24e-04	200	171	6	4409065bc7aa995354c71e0f9d6f3726cf393d6b
ToppCell	mild-CD8+_Tem\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PRR5L SYNE1 KIF21A ANXA6 SLFN5 CEP78	1.24e-04	200	171	6	a7870c5728b2c17d1d0e4fe728599f186966861b
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-CD8+_Tem\|Leuk-UTI / Disease, condition lineage and cell class	SYNE1 KIF21A MIB2 SLFN5 CEP78 SPON2	1.24e-04	200	171	6	aa8104dcb2ba5756a23c25a580bef2360ff25b13
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gpr149_Islr\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TCTE1 HUNK TSPAN9 MYH14 ST8SIA4	1.26e-04	126	171	5	3539a8fdbb52d191f36dce68c38798ad4d2b491a
ToppCell	TCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3\|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9	DYNC2H1 SYNE1 TAF1C BTAF1 PM20D2	1.74e-04	135	171	5	ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DYNC2H1 EGF FMN1 LIMCH1 TRIM50	2.06e-04	140	171	5	5e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_8\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RASGRF1 CC2D2B DPEP3 LIMCH1 EPB41L2	2.13e-04	141	171	5	737237db115721524c44ea4c55aed000e1b00ee5
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-MyoFB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	KIF21A OBSL1 SLC35F4 CLCA2 SPON2	2.13e-04	141	171	5	7ae8ead02e5aeb4106c4a30c08a7a061da3a5d6a
Disease	triacylglycerol 46:2 measurement	GTF3C2 MYO3B CSMD1	5.87e-05	14	164	3	EFO_0010402
Disease	voltage-gated potassium channel subunit beta-2 measurement	NLRP12 KCNAB2	9.18e-05	3	164	2	EFO_0802219
Disease	3-M syndrome	OBSL1 CUL7	9.18e-05	3	164	2	cv:C1848862
Disease	3-M syndrome (is_implicated_in)	OBSL1 CUL7	9.18e-05	3	164	2	DOID:0060241 (is_implicated_in)
Disease	oligodendroglioma (is_implicated_in)	EGF MGMT	9.18e-05	3	164	2	DOID:3181 (is_implicated_in)
Disease	S-warfarin measurement	CLCA2 FMN1 HACE1 CNTN3 ST8SIA4	2.13e-04	97	164	5	EFO_0803323
Disease	Pure gonadal dysgenesis 46,XY	MAP3K1 CBX2	4.54e-04	6	164	2	cv:C2936694
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2B1 ATP2B2	4.54e-04	6	164	2	DOID:0050429 (implicated_via_orthology)
Disease	lumbar disc degeneration	DYNC2H1 MYH14 CSMD1	4.99e-04	28	164	3	EFO_0004994
Disease	urinary albumin to creatinine ratio	CACNA1S CYP26A1 TSPAN9 STAB1 GTF3C2 ST8SIA6	5.12e-04	179	164	6	EFO_0007778
Disease	triacylglycerol 50:4 measurement	MBL2 RBKS MGMT	6.13e-04	30	164	3	EFO_0010411
Disease	toll/interleukin-1 receptor domain-containing adapter protein measurement	NLRP12 RPUSD4	6.33e-04	7	164	2	EFO_0802134
Disease	Swyer Syndrome	MAP3K1 CBX2	6.33e-04	7	164	2	C2936694
Disease	Gonadal Dysgenesis, 46,XY	MAP3K1 CBX2	8.41e-04	8	164	2	C0018054
Disease	Disproportionate short stature	DYNC2H1 OBSL1 CUL7 TRIP11	9.08e-04	77	164	4	C0878659
Disease	nicotine dependence	PSMA4 ICE1 AK2 CAMSAP2	9.53e-04	78	164	4	EFO_0003768
Disease	atopic eczema, psoriasis	PRR5L ANXA6 MGMT	1.05e-03	36	164	3	EFO_0000274, EFO_0000676
Disease	mean corpuscular hemoglobin concentration	CUL1 PRR5L CARMIL1 LRSAM1 PPCDC LIN9 DMXL1 GIPR EGF CLCN6 KIF4B PAN3 ABCC10 EPB41L2 SENP7	1.33e-03	1105	164	15	EFO_0004528
Disease	triacylglycerol 50:3 measurement	MGMT GTF3C2 CSMD1	1.33e-03	39	164	3	EFO_0010410
Disease	diabetes mellitus biomarker	RASGRF1 GIPR	1.34e-03	10	164	2	EFO_0006842
Disease	mean reticulocyte volume	CAD NLRX1 PPCDC DRAM2 HPS3 GIPR CLCN6 IFRD2 LPIN2 POLI ABCC10 EPB41L2	1.77e-03	799	164	12	EFO_0010701
Disease	Colorectal Carcinoma	CAD SYNE1 WNT8B OBSCN CLSTN2 MSH2 HPS3 VRTN ADAMTS18 ST8SIA4 CAMSAP2	1.97e-03	702	164	11	C0009402
Disease	esophagus squamous cell carcinoma (is_implicated_in)	MSH2 MAP3K1 MGMT	2.02e-03	45	164	3	DOID:3748 (is_implicated_in)
Disease	mean arterial pressure, alcohol drinking	ICE1 FIGN CLCN6 ATP2B1	2.21e-03	98	164	4	EFO_0004329, EFO_0006340
Disease	systolic blood pressure, alcohol consumption measurement	FIGN CLCN6 ATP2B1	2.28e-03	47	164	3	EFO_0006335, EFO_0007878
Disease	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	GIPR ST8SIA6	2.67e-03	14	164	2	EFO_0004307, EFO_0008464
Disease	Alzheimer disease, visuospatial impairment	AARS2 CSMD1	2.67e-03	14	164	2	EFO_0009752, MONDO_0004975
Disease	mean arterial pressure, alcohol consumption measurement	FIGN CLCN6 ATP2B1	3.05e-03	52	164	3	EFO_0006340, EFO_0007878
Disease	health literacy measurement	TLK1 UTP20 CSMD1	3.22e-03	53	164	3	EFO_0010104
Disease	response to cisplatin, platinum measurement	FIGN MYH14 CSMD1	3.22e-03	53	164	3	EFO_0010154, GO_0072718
Disease	neuritic plaque measurement	DYNC2H1 KIF21A MBL2 ICE1 TLK1 HACE1 CSMD1	3.49e-03	349	164	7	EFO_0006798
Disease	migraine disorder	INHBA SDR9C7 MYO3B SV2C LIMCH1 ATP2B1 EPB41L2	3.94e-03	357	164	7	MONDO_0005277
Disease	triacylglycerol 48:1 measurement	GTF3C2 CSMD1	3.95e-03	17	164	2	EFO_0010404
Disease	Hallux valgus	WDR27 CLCA2 HACE1	4.57e-03	60	164	3	HP_0001822
Disease	triacylglycerol 46:1 measurement	GTF3C2 CSMD1	5.46e-03	20	164	2	EFO_0010401

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGNLAAADLILACGL	BDKRB2	96	P30411
DLLTAEKGGLCIFLN	nan	461	Q9N2K0
LALNCQLLKIIDLGG	AMN1	136	Q8IY45
SIKVSCLGLEGNLQG	ARHGEF25	411	Q86VW2
RDCLSQSGKLAEELG	C8orf86	26	Q6ZUL3
NNKPGDALCVLGLTL	AMZ1	166	Q400G9
ARLLTAAKGQNCGGL	CSMD1	21	Q96PZ7
GVLKVLAQLGLGFSC	AZIN2	76	Q96A70
GADLKVLCNEAGLCA	SPATA5	561	Q8NB90
NQKCGLLGKDSLLRD	CCDC96	496	Q2M329
ALCLELLVGNGADVN	ANKRD28	286	O15084
AAAAGGNLECLNLLL	ANKRD28	411	O15084
CGLLLQRAETGSKGQ	GIPR	16	P48546
QVGCGKSSLLLAILG	ABCC9	706	O60706
LLCKNGETLLGAVNF	ARFIP2	191	P53365
GEGCLALPKLNLQFL	AQR	446	O60306
CGLTNEGAKALLEAL	CEP78	266	Q5JTW2
GRCGLDLIVQAKSGT	DDX20	96	Q9UHI6
AADLLSCTGLGLQDV	AMIGO3	41	Q86WK7
LGVGCLEKLGNLQTL	CD180	361	Q99467
CKEGLDINSLESLGQ	CLSTN2	541	Q9H4D0
GNGTEELCLLTSGKL	CC2D2B	606	Q6DHV5
QGGETLDECGLKFLL	DMXL1	1531	Q9Y485
AASCQKRGLALDGKL	ARR3	276	P36575
VGNKTECALLGLLLD	ATP2B1	541	P20020
GNKTECGLLGFVLDL	ATP2B2	566	Q01814
GLAGLGRVAKALQLC	ADAMTS18	21	Q8TE60
ACQGILALLDLNASG	CAPN14	561	A8MX76
DTSGDFLKALLALCG	ANXA6	656	P08133
QCQESGASLVLLGKK	INHBA	246	P08476
IIGDTGVGKSCLLLQ	RAB2A	11	P61019
IIGDTGVGKSCLLLQ	RAB2B	11	Q8WUD1
KGAGVNLILDCIGGS	TP53I3	206	Q53FA7
EKGNLLPNGALACSL	FMN1	216	Q68DA7
AECGVLLQLAKDAAG	P3H3	476	Q8IVL6
ALLALCLLGAGAQDF	NPTX1	11	Q15818
DAGEAALVLLKRGCQ	RBKS	216	Q9H477
CAAGGCLIELAQELL	ANO7	631	Q6IWH7
LVLNGLGLADSGCVS	OBSL1	1596	O75147
GCGKSSLLAAIAGEL	ABCC10	636	Q5T3U5
GKTLLGRCIASQLGA	FIGN	531	Q5HY92
SCNHIGLDGGKQLLE	TCTE1	426	Q5JU00
TLLGNGAIVCAVKLD	OR11H6	56	Q8NGC7
KNCNLRGATLAGTDL	KCTD9	336	Q7L273
LLEGGNGLSCISSEL	KLHL31	36	Q9H511
NSSLEKLDLGDCDLG	LRRC34	206	Q8IZ02
DLLCHTGGLSKLGLE	PRAMEF17	396	Q5VTA0
LLQIKCLAEGGDLNS	LIN9	471	Q5TKA1
LLTQSGKVLACGLNE	NEK9	546	Q8TD19
NSLGEQEACLDLGSK	FER1L6-AS1	36	Q8NA97
QLCLLLGSALGGVFK	MFSD4A	61	Q8N468
GTAAILQFLCKESGL	LRSAM1	196	Q6UWE0
LSGCEQGLHEIKLLG	MGMT	21	P16455
NLETPLCKNGFLLDG	AK2	86	P54819
GVDIKLGVCANGLLI	EPB41L2	416	O43491
AAQKLCRLLGLGVTD	MYH14	396	Q7Z406
EGGNKLVCSGLLQAS	PCYOX1	251	Q9UHG3
ATQELGRLKLCEGAG	PLXNC1	216	O60486
DQLVGQKFSSLLEGC	MUC19	1566	Q7Z5P9
ALQNGCAGALLKLPF	CUL7	1196	Q14999
KCSLLGDISDGKNLV	FAM214A	546	Q32MH5
LNKAGLVLGILSCLG	DRAM2	91	Q6UX65
KEGISINCGLLALGN	KIF21B	291	O75037
GSVECLVLLLKKGAN	HACE1	76	Q8IYU2
AGSDEDCVLLLKNGQ	MBL2	216	P11226
GEAALNDAKCKLAGL	KRT82	371	Q9NSB4
DSFLELLGGKNGVCQ	PLA2G12B	51	Q9BX93
GLQLNSLGPEACKDL	NLRX1	756	Q86UT6
YLKGLEVLELGGCSN	FBXL14	141	Q8N1E6
SAAEGCLGLEQLTLQ	FBXL14	196	Q8N1E6
NLGKSGLRVSCLGLG	KCNAB2	41	Q13303
GLGEEASSENKCLLL	PRR5L	311	Q6MZQ0
KALGLLCGKDADACN	NPC1	171	O15118
GQVLCKAELLVLGGD	OBSCN	6436	Q5VST9
GKVVLALACNSLAGI	PAN3	691	Q58A45
VVAGVLGNLLLDKCL	OR6S1	311	Q8NH40
VLLNLAGFILGCQGA	FAM189A2	16	Q15884
ELASLCLQDGGALKN	GAL3ST2	316	Q9H3Q3
KISGLLLEGCSFDGN	DYNC2H1	4216	Q8NCM8
NDCGALKAADVGISL	ATP13A2	881	Q9NQ11
SQKGCLALSLLELLG	CLCN6	121	P51797
DCNGKDTGSLLLLNV	ICE1	1276	Q9Y2F5
LKAQATNKCGLGLDL	CBX2	276	Q14781
TGCDSGFGNLLAKQL	SDR9C7	31	Q8NEX9
LSALKQLLLDCGLGN	BTAF1	1616	O14981
QLLLDCGLGNGSTSE	BTAF1	1621	O14981
DGKTCLALDGHQLLA	EGF	776	P01133
ACRAGDVGVLKLQLA	ANKZF1	501	Q9H8Y5
LGCLNLGSSLGSLDQ	CACNA1S	1846	Q13698
LKDCIFDLCLGGGNL	FCGBP	3886	Q9Y6R7
NQGLAAIEKCGEAAL	CUL1	346	Q13616
CTLLGALDELSQGKG	ARFGEF3	431	Q5TH69
KLIDFGLSNCAGILG	HUNK	201	P57058
ELNSKCVGALVGLAV	CTR9	226	Q6PD62
GEEQALAAAVLGLLC	IFRD2	196	Q12894
RLALLGKSGLSCQVG	CEP192	1166	Q8TEP8
GLLCLGNVISALGDD	KIF4A	266	O95239
GLLCLGNVISALGDD	KIF4B	266	Q2VIQ3
LGLACNHNLKGVSLD	CARMIL1	446	Q5VZK9
SEAGQGCKDALQLLI	CYP26A1	261	O43174
QEVLGCQAKLLSGGL	C19orf54	181	Q5BKX5
AGKALLGRCLATQLG	FIGNL2	436	A6NMB9
EGLNSSQKLACLIGV	DPEP3	181	Q9H4B8
LGLTGCAGVASNKLL	POLI	216	Q9UNA4
DCILARVGAGDSQLK	MSH2	706	P43246
AGTCLGILANDGVLL	PSMA4	31	P25789
ENLLKDGTDGCALAA	CAMSAP2	246	Q08AD1
KQLILLSFIGCLGGE	CNTN3	6	Q9P232
QDGAGVPCLSLKLLN	DRP2	51	Q13474
TGLENGILLCELLNA	LIMCH1	46	Q9UPQ0
GSKAALANLCIGDVI	PDLIM1	36	O00151
LAAEGRVLKALQGCA	MIB2	776	Q96AX9
LCLSLELLLEAGAGN	PCDHGA1	16	Q9Y5H4
LAGLCGNFDLKTINE	OTOG	1111	Q6ZRI0
LLELCKGQAGELAVG	MAP3K1	706	Q13233
DADLNLIKGGGGCLT	RPIA	166	P49247
ALGSGKEELNLVCKL	RPUSD4	331	Q96CM3
GLTNKLQVGDLDSCL	UTP20	1911	O75691
TKGGLGVTNEDLECL	SENP7	756	Q9BQF6
GKALCALLLATLGAA	SPON2	11	Q9BUD6
ALCKAAAVLGNLIFG	SV2C	676	Q496J9
CNDLLKGLGTVKDSL	SYNE1	7286	Q8NF91
GDLLVGCTNKLVLFS	HPS3	146	Q969F9
LLSGKAQGVVDRGLC	RIMBP3	931	Q9UFD9
LLLFRLGAEASCQKG	TAF1C	421	Q15572
LQTLFLVDCGIGDSK	PRAMEF19	351	Q5SWL8
LVGLNVLDANLCLKG	RUFY1	256	Q96T51
GNSGILLDSECGKEI	ST8SIA4	146	Q92187
NGGILNKSLCGTEID	ST8SIA6	191	P61647
VTLLGQIGCDSNGKL	POLA2	251	Q14181
THLLQDCLGGDAKLL	KIF25	321	Q9UIL4
NGNDQALLLLCGKET	MRGPRX2	16	Q96LB1
KLTSGRQLAAGNGLC	SLC35F4	11	A4IF30
GGKALDLAALSCNSN	RASGRF1	766	Q13972
GGACNGRSELELLKL	PM20D2	11	Q8IYS1
VASVGKGQRCGLLLD	AARS2	546	Q5JTZ9
DLIGGKCELLSDDSL	APEH	286	P13798
ILVTSGDDKLLGNCL	CLCA2	416	Q9UQC9
NTLGKVASGICDNLL	PPCDC	106	Q96CD2
CLKALGQEADKGLSG	RECQL5	246	O94762
EKDQELICGLCGLLG	TRIM74	101	Q86UV6
GAGGLGCELLKNLAL	UBA3	76	Q8TBC4
DLKPGNILLVDGTAC	TLK1	586	Q9UKI8
CLENKTLGLLGTEGR	WNT8B	256	Q93098
EGGKVILGSCDLLQL	ZNF132	196	P52740
GQEGVAAALAACKIL	TRPM5	541	Q9NZQ8
AKEGISINCGLLALG	KIF21A	291	Q7Z4S6
LKEASCGLAQGQELG	PLEKHG4B	951	Q96PX9
CSLNTLLLGGVNKIA	SPINT4	16	Q6UDR6
CGKNISVLGQAGLLT	SYCP2	76	Q9BX26
GLFLLGCIKNDIQCS	TRIM49C	376	P0CI26
ALLVLGLCALAGSEK	TFF2	11	Q03403
CGGIALILSGLKANN	TPP2	456	P29144
LCALGNQLCALLGAD	XPO5	326	Q9HAV4
KANLVLLSGANEGKC	NRDC	606	O43847
SDNLLGDAGLQLLCE	RNH1	121	P13489
DGISTCNGKLLDVLA	STAB1	2316	Q9NY15
LDCLCGDNTGKGLSL	VAT1L	251	Q9HCJ6
INGQDFLCCDLGKLL	TTC21A	791	Q8NDW8
RGLAAALLLCQNKGL	SART1	636	O43290
ALNCGVELTKAGVLA	CAD	481	P27708
GQLCNTKDLLLGKLD	TRIP11	1296	Q15643
EKDQELICGLCGLLG	TRIM73	101	Q86UV7
ALLALGLKCGGTLEE	SF3A3	266	Q12874
LGLLALACSDGKVLL	GTF3C2	496	Q8WUA4
LGGECDKAVASQLGL	ZMYM1	6	Q5SVZ6
ADQKVLCLLASLFGG	WDR27	366	A2RRH5
SKTGLGLLQDSGLCV	POLR1B	441	Q9H9Y6
GLLQDSGLCVVADKL	POLR1B	446	Q9H9Y6
CEGLEGLIGASLEAK	VRTN	21	Q9H8Y1
EKDQELICGLCGLLG	TRIM50	101	Q86XT4
VQLLASCIDKGDLSG	XIRP1	926	Q702N8
AVCALLNSGGGIIKA	SLFN5	46	Q08AF3
ELSGLGDRKSLLNQC	TOE1	66	Q96GM8
GATSGKLLLEADELC	ZBTB22	251	O15209
GLADAGLDLKGTCIS	ZFYVE9	441	O95405
TQLLFLKAACVGQGL	UFL1	291	O94874
GCLGAIKENKCLLLS	TSPAN9	71	O75954
CIDALKLDSASFLGG	ELFN2	551	Q5R3F8
LSLCGGLSENGEISK	LPIN2	471	Q92539
TNNALGDTGVRLLCK	NLRP12	1006	P59046
LELCNGGSVTELVKG	MYO3B	106	Q8WXR4