Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

STAB2 LDLR STAB1 SORL1

2.21e-06161214GO:0005041
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

STAB2 LDLR STAB1 SORL1

3.68e-06181214GO:0030169
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

STAB2 LDLR STAB1 SORL1

7.09e-06211214GO:0030228
GeneOntologyMolecularFunctionlipoprotein particle binding

STAB2 LDLR STAB1 SORL1

5.81e-05351214GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

STAB2 LDLR STAB1 SORL1

5.81e-05351214GO:0071814
GeneOntologyBiologicalProcessneuroinflammatory response

LDLR ZEB2 PTPRC CLU VPS13A PLCG2

2.89e-051011216GO:0150076
GeneOntologyBiologicalProcessmammillary body development

ZEB2 FOXB1

3.41e-0521212GO:0021767
GeneOntologyBiologicalProcessmammillary axonal complex development

ZEB2 FOXB1

3.41e-0521212GO:0061373
GeneOntologyCellularComponentcell projection membrane

TRPM6 TCTN3 PDE6A ANPEP EPB41L5 AQP1 SHANK2 CLTB ANTXR1 PLCG2 ATP1B2

3.90e-0543112011GO:0031253
GeneOntologyCellularComponentprocentriole

CEP192 CEP152

9.77e-0531202GO:0120098
GeneOntologyCellularComponentHULC complex

UBE2A UBE2B

1.95e-0441202GO:0033503
GeneOntologyCellularComponentdistal axon

AQP1 SLC1A1 ZNF804A TENM2 NEO1 SHANK2 FEZ1 CLU CDH8 AP3D1

2.08e-0443512010GO:0150034
GeneOntologyCellularComponentprocentriole replication complex

CEP192 CEP152

4.83e-0461202GO:0120099
DomainAlpha_kinase

TRPM6 ALPK1 EEF2K

4.97e-0661193PF02816
DomainMHCK_EF2_kinase

TRPM6 ALPK1 EEF2K

4.97e-0661193IPR004166
DomainALPHA_KINASE

TRPM6 ALPK1 EEF2K

4.97e-0661193PS51158
DomainAlpha_kinase

TRPM6 ALPK1 EEF2K

4.97e-0661193SM00811
DomainHud_Sxl_RNA

RBMS2 ELAVL2 ELAVL1

2.93e-05101193IPR002343
DomainFAS1

STAB2 STAB1

2.40e-0441192SM00554
DomainFAS1_domain

STAB2 STAB1

2.40e-0441192IPR000782
DomainELAD_HUD_SF

ELAVL2 ELAVL1

2.40e-0441192IPR006548
Domain-

STAB2 STAB1

2.40e-04411922.30.180.10
DomainFAS1

STAB2 STAB1

2.40e-0441192PS50213
DomainFasciclin

STAB2 STAB1

2.40e-0441192PF02469
DomainTF_Brachyury

TBX2 TBX6

5.94e-0461192IPR002070
DomainEGF-like_dom

STAB2 IMPG1 TENM2 LDLR STAB1 NRG3 SORL1

1.09e-032491197IPR000742
DomainProt_inh_cystat_CS

CST6 CSTB

1.41e-0391192IPR018073
DomainEGF-like_CS

STAB2 TENM2 LDLR ITGB7 STAB1 NRG3 SORL1

1.42e-032611197IPR013032
DomainPTPc

PTPN11 PTPN13 PTPRC

1.54e-03361193SM00194
DomainEGF_2

STAB2 TENM2 LDLR ITGB7 STAB1 NRG3 SORL1

1.55e-032651197PS01186
DomainE3_UB_ligase_RBR

ARIH2 ARIH1

1.75e-03101192IPR031127
DomainTYR_PHOSPHATASE_PTP

PTPN11 PTPN13 PTPRC

1.95e-03391193PS50055
Domain-

TENM2 LDLR SORL1

1.95e-033911932.120.10.30
DomainLDLR_class-A_CS

LDLR RXFP1 SORL1

2.10e-03401193IPR023415
DomainGFP-like

STAB2 STAB1

2.13e-03111192IPR023413
Domain-

STAB2 STAB1

2.13e-031111922.40.155.10
DomainPTPase_domain

PTPN11 PTPN13 PTPRC

2.25e-03411193IPR000242
DomainY_phosphatase

PTPN11 PTPN13 PTPRC

2.25e-03411193PF00102
DomainEGF_dom

STAB2 STAB1

2.55e-03121192IPR024731
DomainCYSTATIN

CST6 CSTB

2.55e-03121192PS00287
DomainEGF_3

STAB2 STAB1

2.55e-03121192PF12947
DomainLdl_recept_a

LDLR RXFP1 SORL1

2.94e-03451193PF00057
DomainLink_dom

STAB2 STAB1

3.00e-03131192IPR000538
DomainXlink

STAB2 STAB1

3.00e-03131192PF00193
DomainLINK_2

STAB2 STAB1

3.00e-03131192PS50963
DomainLINK

STAB2 STAB1

3.00e-03131192SM00445
DomainLINK_1

STAB2 STAB1

3.00e-03131192PS01241
Domain6-blade_b-propeller_TolB-like

TENM2 LDLR SORL1

3.14e-03461193IPR011042
Domain-

LDLR RXFP1 SORL1

3.14e-034611934.10.400.10
DomainIBR

ARIH2 ARIH1

3.48e-03141192PF01485
DomainSEA

IMPG1 MUC16

3.48e-03141192SM00200
DomainIBR

ARIH2 ARIH1

3.48e-03141192SM00647
DomainLdl_recept_b

LDLR SORL1

3.48e-03141192PF00058
DomainLDLRB

LDLR SORL1

3.48e-03141192PS51120
DomainLDLRA_1

LDLR RXFP1 SORL1

3.54e-03481193PS01209
DomainLDrepeatLR_classA_rpt

LDLR RXFP1 SORL1

3.75e-03491193IPR002172
DomainLDLa

LDLR RXFP1 SORL1

3.75e-03491193SM00192
DomainLDLRA_2

LDLR RXFP1 SORL1

3.75e-03491193PS50068
DomainZnf_RING_CS

ARIH2 RNF10 TRIM8 HLTF SCAF11

3.91e-031631195IPR017907
DomainEGF

STAB2 TENM2 LDLR STAB1 NRG3 SORL1

3.97e-032351196SM00181
DomainEGF_3

STAB2 TENM2 LDLR STAB1 NRG3 SORL1

3.97e-032351196PS50026
Domain-

IMPG1 MUC16

4.00e-031511923.30.70.960
DomainLY

LDLR SORL1

4.00e-03151192SM00135
DomainIBR_dom

ARIH2 ARIH1

4.00e-03151192IPR002867
DomainLDLR_classB_rpt

LDLR SORL1

4.00e-03151192IPR000033
Domainp53-like_TF_DNA-bd

NFAT5 TBX2 TBX6

4.69e-03531193IPR008967
DomainTF_T-box

TBX2 TBX6

5.14e-03171192IPR001699
DomainTBOX

TBX2 TBX6

5.14e-03171192SM00425
DomainTF_T-box_CS

TBX2 TBX6

5.14e-03171192IPR018186
Domain-

TBX2 TBX6

5.14e-031711922.60.40.820
DomainTBOX_3

TBX2 TBX6

5.14e-03171192PS50252
DomainT-box

TBX2 TBX6

5.14e-03171192PF00907
DomainCY

CST6 CSTB

5.14e-03171192SM00043
DomainTBOX_1

TBX2 TBX6

5.14e-03171192PS01283
DomainTBOX_2

TBX2 TBX6

5.14e-03171192PS01264
DomainCystatin_dom

CST6 CSTB

5.76e-03181192IPR000010
DomainCystatin

CST6 CSTB

5.76e-03181192PF00031
DomainEGF_1

STAB2 TENM2 LDLR ITGB7 STAB1 NRG3

5.88e-032551196PS00022
DomainPTPc_motif

PTPN11 PTPN13 PTPRC

6.33e-03591193SM00404
DomainTyr_Pase_cat

PTPN11 PTPN13 PTPRC

6.33e-03591193IPR003595
Pubmed

Systems biology of the 2-cell mouse embryo.

MBTD1 ELAVL2 ELAVL1 BTG4

1.01e-0713122415237213
Pubmed

Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression.

STAB2 LDLR STAB1

1.68e-074122336325910
Pubmed

Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions.

APOB LDLR PTPRC

1.68e-074122322144566
Pubmed

Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent.

SYCP2 UBE2B BRCA2 BRDT SPATA22

2.92e-0740122520378615
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

MECOM CEP192 LDLR ZEB2 BUB1B MKI67 CEP152 MED23

3.03e-07184122832908313
Pubmed

Alpha-kinases: a new class of protein kinases with a novel catalytic domain.

TRPM6 ALPK1 EEF2K

8.36e-076122310021370
Pubmed

Mature mRNA processing that deletes 3' end sequences directs translational activation and embryonic development.

GEMIN5 ELAVL2 ELAVL1

1.46e-067122338000026
Pubmed

Intra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis.

MECOM PTPRC MKI67

2.33e-068122322558218
Pubmed

Tagging genes with cassette-exchange sites.

MBTD1 GEMIN5 RFX7 PTPN11 MKI67 NAV2 SECISBP2 MED23 ZNF292

3.01e-06335122915741177
Pubmed

Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.

LDLR CLU SORL1

3.48e-069122320005821
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

PLXNA3 PTBP3 TCTN3 MBTD1 CDV3 GJC1 MECOM PTPN11 FEZ1 RALGPS1 ARIH2 CLTB VPS13A ELAVL2 CEP152 CCDC33

5.68e-0612151221615146197
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TRPM6 MBTD1 MBNL1 AKNAD1 GEMIN5 APOB CEP192 LDLR PPARGC1A PTPN13 PTPRC RASSF1 PEAK1 NFAT5 BTG4

6.34e-0610841221511544199
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

PTBP3 CDV3 RBMS2 MBNL1 EPB41L5 GEMIN5 DARS1 PTPN13 MKI67 SECISBP2 MAP2K3 ZNF292

9.74e-067241221236232890
Pubmed

Comparison of apolipoprotein B metabolism in familial defective apolipoprotein B and heterogeneous familial hypercholesterolemia.

APOB LDLR

1.22e-052122211947895
Pubmed

Increased production of VLDL apoB-100 in subjects with familial hypercholesterolemia carrying the same null LDL receptor gene mutation.

APOB LDLR

1.22e-052122214967814
Pubmed

[A genetic and clinical study in a family with familial hypercholesterolemia].

APOB LDLR

1.22e-052122221418831
Pubmed

Lymphatic insufficiency leads to distinct myocardial infarct content assessed by magnetic resonance TRAFFn, T1ρ and T2 relaxation times.

APOB LDLR

1.22e-052122236709358
Pubmed

Exploiting Glutamine Consumption in Atherosclerotic Lesions by Positron Emission Tomography Tracer (2S,4R)-4-18F-Fluoroglutamine.

APOB LDLR

1.22e-052122235145523
Pubmed

Common mutations of familial hypercholesterolemia patients in Taiwan: characteristics and implications of migrations from southeast China.

APOB LDLR

1.22e-052122222353362
Pubmed

The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.

UBE2A UBE2B

1.22e-052122215169909
Pubmed

FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products.

STAB2 STAB1

1.22e-052122212473645
Pubmed

Targeting HuR-Vav3 mRNA interaction prevents Pseudomonas aeruginosa adhesion to the cystic fibrosis airway epithelium.

ELAVL1 VAV3

1.22e-052122236602863
Pubmed

Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase.

UBE2A UBE2B

1.22e-052122212556476
Pubmed

Deletion of the murine ortholog of human 9p21.3 locus promotes atherosclerosis by increasing macrophage proinflammatory activity.

APOB LDLR

1.22e-052122236950286
Pubmed

LDLR and ApoB are major genetic causes of autosomal dominant hypercholesterolemia in a Taiwanese population.

APOB LDLR

1.22e-052122217964958
Pubmed

Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.

UBE2A UBE2B

1.22e-05212221717990
Pubmed

Immunization of Chlamydia pneumoniae (Cpn)-infected Apob(tm2Sgy)Ldlr(tm1Her)/J mice with a combined peptide of Cpn significantly reduces atherosclerotic lesion development.

APOB LDLR

1.22e-052122224349031
Pubmed

Safeguarding genome stability: RASSF1A tumor suppressor regulates BRCA2 at stalled forks.

BRCA2 RASSF1

1.22e-052122225927241
Pubmed

Novel mutations identification in exon 4 of LDLR gene in patients with moderate hypercholesterolemia in a Venezuelan population.

APOB LDLR

1.22e-052122220019594
Pubmed

Echium oil reduces atherosclerosis in apoB100-only LDLrKO mice.

APOB LDLR

1.22e-052122222100249
Pubmed

Immunotherapy with tolerogenic apolipoprotein B-100-loaded dendritic cells attenuates atherosclerosis in hypercholesterolemic mice.

APOB LDLR

1.22e-052122221357823
Pubmed

Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr-/-:hApoB+/+ mice and improves cerebral blood flow.

APOB LDLR

1.22e-052122222268108
Pubmed

Capillary Dynamics Regulate Post-Ischemic Muscle Damage and Regeneration in Experimental Hindlimb Ischemia.

APOB LDLR

1.22e-052122237626870
Pubmed

Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31.

UBE2A UBE2B

1.22e-05212221559696
Pubmed

Complete deficiency of the low-density lipoprotein receptor is associated with increased apolipoprotein B-100 production.

APOB LDLR

1.22e-052122215637307
Pubmed

Immunization with a combination of 2 peptides derived from the C5a receptor significantly reduces early atherosclerotic lesion in Ldlr(tm1Her) Apob(tm2Sgy) J mice.

APOB LDLR

1.22e-052122222837469
Pubmed

Hypercholesterolemia Induced Immune Response and Inflammation on Progression of Atherosclerosis in Apob(tm2Sgy) Ldlr(tm1Her)/J Mice.

APOB LDLR

1.22e-052122226178198
Pubmed

Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver.

STAB2 STAB1

1.22e-052122221427291
Pubmed

Combined therapy of dietary fish oil and stearoyl-CoA desaturase 1 inhibition prevents the metabolic syndrome and atherosclerosis.

APOB LDLR

1.22e-052122219834103
Pubmed

Modulation of recombinant antigenic constructs containing multi-epitopes towards effective reduction of atherosclerotic lesion in B6;129S-Ldlr(tm1Her)Apob(tm2Sgy)/J mice.

APOB LDLR

1.22e-052122225830298
Pubmed

[Low density lipoprotein receptor gene mutations in patients with clinical diagnosis of familial hypercholesterolemia.].

APOB LDLR

1.22e-052122215477777
Pubmed

The NMR structure of the class I human ubiquitin-conjugating enzyme 2b.

UBE2A UBE2B

1.22e-052122211885984
Pubmed

Cytoplasmic accumulation of the RNA-binding protein HuR stabilizes the ornithine decarboxylase transcript in a murine nonmelanoma skin cancer model.

ODC1 ELAVL1

1.22e-052122220685649
Pubmed

Impact of genetic defects on atherosclerosis in patients suspected of familial hypercholesterolaemia.

APOB LDLR

1.22e-052122211737238
Pubmed

Detection of hypoxia by [18F]EF5 in atherosclerotic plaques in mice.

APOB LDLR

1.22e-052122221372297
Pubmed

Early development of calcific aortic valve disease and left ventricular hypertrophy in a mouse model of combined dyslipidemia and type 2 diabetes mellitus.

APOB LDLR

1.22e-052122225231636
Pubmed

Molecular genetic testing for familial hypercholesterolemia in the Netherlands: a stepwise screening strategy enhances the mutation detection rate.

APOB LDLR

1.22e-052122216792510
Pubmed

Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding.

STAB2 STAB1

1.22e-052122215572036
Pubmed

Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin-deficient mice.

STAB2 STAB1

1.22e-052122238946049
Pubmed

Influence of an asparagine to lysine mutation at amino acid 3516 of apolipoprotein B on low-density lipoprotein receptor binding.

APOB LDLR

1.22e-052122212031600
Pubmed

ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation.

ELAVL2 ELAVL1

1.22e-05212229763509
Pubmed

Gene transfers of vascular endothelial growth factor-A, vascular endothelial growth factor-B, vascular endothelial growth factor-C, and vascular endothelial growth factor-D have no effects on atherosclerosis in hypercholesterolemic low-density lipoprotein-receptor/apolipoprotein B48-deficient mice.

APOB LDLR

1.22e-052122216129816
Pubmed

Potential role of BRCA2 in a mitotic checkpoint after phosphorylation by hBUBR1.

BRCA2 BUB1B

1.22e-052122210749118
Pubmed

Recombinant RXFP1-LDL-A module does not form dimers.

LDLR RXFP1

1.22e-052122224640556
Pubmed

siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids.

APOB LDLR

1.22e-052122221398511
Pubmed

Diagnosis of families with familial hypercholesterolaemia and/or Apo B-100 defect by means of DNA analysis of LDL-receptor gene mutations.

APOB LDLR

1.22e-052122217347910
Pubmed

Mucosal tolerance to a combination of ApoB and HSP60 peptides controls plaque progression and stabilizes vulnerable plaque in Apob(tm2Sgy)Ldlr(tm1Her)/J mice.

APOB LDLR

1.22e-052122223505495
Pubmed

Genetic screening for familial hypercholesterolemia identifies patients not meeting cholesterol treatment guidelines.

APOB LDLR

1.22e-052122233394692
Pubmed

Upregulation of liver VLDL receptor and FAT/CD36 expression in LDLR-/- apoB100/100 mice fed trans-10,cis-12 conjugated linoleic acid.

APOB LDLR

1.22e-052122216957181
Pubmed

Spectrum of mutations in index patients with familial hypercholesterolemia in Singapore: Single center study.

APOB LDLR

1.22e-052122229353225
Pubmed

FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities.

STAB2 STAB1

1.22e-052122212077138
Pubmed

Differential Promoter Methylation of Macrophage Genes Is Associated With Impaired Vascular Growth in Ischemic Muscles of Hyperlipidemic and Type 2 Diabetic Mice: Genome-Wide Promoter Methylation Study.

APOB LDLR

1.22e-052122226085133
Pubmed

Reliable low-density DNA array based on allele-specific probes for detection of 118 mutations causing familial hypercholesterolemia.

APOB LDLR

1.22e-052122215890894
Pubmed

Genetic diagnosis of familial hypercholesterolemia using a DNA-array based platform.

APOB LDLR

1.22e-052122219318025
Pubmed

Combined BubR1 protein down-regulation and RASSF1A hypermethylation in Wilms tumors with diverse cytogenetic changes.

RASSF1 BUB1B

1.22e-052122218286482
Pubmed

Mutational analysis of the LDL receptor and APOB genes in Mexican individuals with autosomal dominant hypercholesterolemia.

APOB LDLR

1.22e-052122221722902
Pubmed

Alternative Splicing of RAD6B and Not RAD6A is Selectively Increased in Melanoma: Identification and Functional Characterization.

UBE2A UBE2B

1.22e-052122231683936
Pubmed

CLU (clusterin) and PPARGC1A/PGC1α coordinately control mitophagy and mitochondrial biogenesis for oral cancer cell survival.

PPARGC1A CLU

1.22e-052122238447939
Pubmed

Familial hypercholesterolemia and coronary heart disease: a HuGE association review.

APOB LDLR

1.22e-052122215321838
Pubmed

Genetic causes of monogenic heterozygous familial hypercholesterolemia: a HuGE prevalence review.

APOB LDLR

1.22e-052122215321837
Pubmed

Familial hypercholesterolemia, peripheral arterial disease, and stroke: a HuGE minireview.

APOB LDLR

1.22e-052122215321839
Pubmed

A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus.

LDLR ELAVL1

1.22e-052122233262333
Pubmed

Molecular testing for familial hypercholesterolaemia-associated mutations in a UK-based cohort: development of an NGS-based method and comparison with multiplex polymerase chain reaction and oligonucleotide arrays.

APOB LDLR

1.22e-052122226748104
Pubmed

Scavenging Endothelium of Pancreatic Islets: Differential Expression of Stabilin-1 and Stabilin-2 in Mice and Humans.

STAB2 STAB1

1.22e-052122227977633
Pubmed

Radiosynthesis and preclinical evaluation of [68Ga]Ga-NOTA-folate for PET imaging of folate receptor β-positive macrophages.

APOB LDLR

1.22e-052122232788595
Pubmed

Linkage genetics of mouse ornithine decarboxylase (Odc).

APOB ODC1

1.22e-05212222575591
Pubmed

Monounsaturated fatty acyl-coenzyme A is predictive of atherosclerosis in human apoB-100 transgenic, LDLr-/- mice.

APOB LDLR

1.22e-052122217277381
Pubmed

Familial defective apolipoprotein B versus familial hypercholesterolemia: an assessment of risk.

APOB LDLR

1.22e-052122215630635
Pubmed

Therapeutic effects of rosuvastatin in hypercholesterolemic prediabetic mice in the absence of low density lipoprotein receptor.

APOB LDLR

1.22e-052122230508567
Pubmed

RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance.

UBE2A UBE2B

1.22e-052122228806395
Pubmed

Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis.

APOB LDLR

1.22e-052122218794388
Pubmed

Increased atherosclerotic lesion calcification in a novel mouse model combining insulin resistance, hyperglycemia, and hypercholesterolemia.

APOB LDLR

1.22e-052122217872464
Pubmed

Liver damage promotes pro-inflammatory T-cell responses against apolipoprotein B-100.

APOB LDLR

1.22e-052122234914849
Pubmed

Functionality of sequence variants in the genes coding for the low-density lipoprotein receptor and apolipoprotein B in individuals with inherited hypercholesterolemia.

APOB LDLR

1.22e-052122220506408
Pubmed

Familial hypercholesterolemia in St-Petersburg: the known and novel mutations found in the low density lipoprotein receptor gene in Russia.

APOB LDLR

1.22e-052122215701167
Pubmed

Identifying Stabilin-1 and Stabilin-2 Double Knockouts in Reproduction and Placentation: A Descriptive Study.

STAB2 STAB1

1.22e-052122233008099
Pubmed

ApoB100,LDLR-/- mice exhibit reduced electroretinographic response and cholesteryl esters deposits in the retina.

APOB LDLR

1.22e-052122218385042
Pubmed

Frequency of low-density lipoprotein receptor gene mutations in patients with a clinical diagnosis of familial combined hyperlipidemia in a clinical setting.

APOB LDLR

1.22e-052122219007590
Pubmed

The expression of aquaporin-1 in the medulla of the kidney is dependent on the transcription factor associated with hypertonicity, TonEBP.

AQP1 NFAT5

1.22e-052122220639513
Pubmed

Impact of sex and sex hormones on pathophysiology and progression of aortic stenosis in a murine model.

APOB LDLR

1.22e-052122236029186
Pubmed

Exploring the transcriptomic network of multi-ligand scavenger receptor Stabilin-1- and Stabilin-2-deficient liver sinusoidal endothelial cells.

STAB2 STAB1

1.22e-052122233130055
Pubmed

The relationship of molecular genetic to clinical diagnosis of familial hypercholesterolemia in a Danish population.

APOB LDLR

1.22e-052122215823288
Pubmed

Sterol-independent repression of low density lipoprotein receptor promoter by peroxisome proliferator activated receptor gamma coactivator-1alpha (PGC-1alpha).

LDLR PPARGC1A

1.22e-052122219322023
Pubmed

Mutational analysis in UK patients with a clinical diagnosis of familial hypercholesterolaemia: relationship with plasma lipid traits, heart disease risk and utility in relative tracing.

APOB LDLR

1.22e-052122216389549
Pubmed

Impact of genetic defects on coronary atherosclerosis in patients suspected of having familial hypercholesterolaemia.

APOB LDLR

1.22e-052122212492446
Pubmed

Increased intestinal cholesterol absorption in autosomal dominant hypercholesterolemia and no mutations in the low-density lipoprotein receptor or apolipoprotein B genes.

APOB LDLR

1.22e-052122217566095
Pubmed

Screening of APOB gene mutations in subjects with clinical diagnosis of familial hypercholesterolemia.

APOB LDLR

1.22e-052122216596945
Pubmed

Comparison of genetic versus clinical diagnosis in familial hypercholesterolemia.

APOB LDLR

1.22e-052122218940289
Pubmed

T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation.

OLFM4 ITGB7

1.22e-052122231278057
Pubmed

Mutation in apolipoprotein B associated with hypobetalipoproteinemia despite decreased binding to the low density lipoprotein receptor.

APOB LDLR

1.22e-052122215797858
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

PTBP3 SMG1 CDV3 EP400 DCP2 MBNL1 EVI2B DARS1 ODC1 RFX7 ITGB7 ZEB2 PTPN11 SAMD9L PTPRC SECISBP2 SCAF11 VAV3 GPR171 ARIH1 NFAT5 ZNF292 SORL1

3.53e-07149212223M40023
CoexpressionAZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP

PTBP3 CDV3 AOX1 PTPN11 FEZ1 ELAVL2 SORL1

2.13e-061261227M2309
CoexpressionPUJANA_ATM_PCC_NETWORK

CDV3 EP400 RBMS2 DCP2 MBNL1 DARS1 ODC1 ZNF804A ITGB7 PTPRC RASSF1 ARIH2 CLTB MKI67 ELAVL1 SCAF11 GPR171 PLCG2 CDH8 TBX6

6.71e-06139412220M9585
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN

MON2 PLXNA3 CDV3 CEP192 SLC1A1 ZEB2 NEO1 SAMD9L UBE2B LRRC42 RALGPS1 NAV2 ELAVL1 TMEM108 ATP1B2 TBX2 SORL1

1.42e-05110212217M2369
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN

MON2 PLXNA3 CDV3 CEP192 SLC1A1 ZEB2 NEO1 SAMD9L UBE2B LRRC42 RALGPS1 NAV2 ELAVL1 TMEM108 ATP1B2 TBX2 SORL1

1.83e-05112412217MM1070
CoexpressionGSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_DN

EVI2B RFX7 BUB1B MKI67 TMEM108 ZNF292 SORL1

4.33e-052001227M8088
CoexpressionGSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP

MBTD1 USP22 DCP2 TRIM8 HLTF ELAVL1 SORL1

4.33e-052001227M3277
CoexpressionWEBER_METHYLATED_HCP_IN_FIBROBLAST_DN

CABYR SYCP2 BRDT SPATA22

4.79e-05431224M16646
CoexpressionLAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE

TRPM6 MECOM CA10 ZNF518A PPARGC1A NAV2 VAV3

5.55e-052081227M39233
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000

EPB41L5 MECOM AQP1 CA10 TENM2 PPARGC1A FOXB1 PTPN13 FEZ1 CLU ANTXR1 ELAVL2 TMEM108 PEAK1 NRG3 ARHGAP20 CDH8 CCDC33 TBX2

2.32e-0697612019Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_200

EPB41L5 PPARGC1A SAMD9L HLTF VAV3 NFAT5 SORL1

3.00e-051561207gudmap_developingKidney_e15.5_cortic collect duct_200
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000

ANPEP MUC16 ALPK1 ZEB2 NEO1 PTPN13 CLU NAV2 ANTXR1 PEAK1 ARHGAP20 ATP1B2 NFAT5 AKAP7

7.60e-0574012014gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_100

MUC16 PPARGC1A CLU ARHGAP20 ATP1B2

8.05e-05781205gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_100
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500

MECOM AQP1 TENM2 PPARGC1A FEZ1 ANTXR1 PEAK1 NRG3 ARHGAP20 CDH8 TBX2

1.05e-0448912011Facebase_RNAseq_e8.5_Paraxial Mesoderm_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000

EPB41L5 MECOM AQP1 TENM2 PPARGC1A FEZ1 RALGPS1 NAV2 ANTXR1 ELAVL2 PEAK1 NRG3 ARHGAP20 CDH8 CCDC33 TBX2

1.35e-0498412016Facebase_RNAseq_e10.5_Olfactory Pit_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

ANPEP DCP2 MUC16 ALPK1 ZEB2 NEO1 PTPN13 NAV2 ANTXR1 PEAK1 ARHGAP20 ATP1B2 NFAT5 AKAP7

1.38e-0478312014gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#2

EPB41L5 MECOM PPARGC1A FEZ1 RALGPS1 ELAVL2 NRG3 CDH8

1.90e-042791208Facebase_RNAseq_e10.5_Olfactory Pit_1000_K2
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_200

PPARGC1A SAMD9L HLTF

2.17e-04211203gudmap_developingKidney_e15.5_cortic collect duct_200_k4
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_100

PPARGC1A CLU ATP1B2

2.17e-04211203gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k3_100
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200

MUC16 PPARGC1A CLU TMEM108 ARHGAP20 ATP1B2

2.36e-041531206gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_200
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#3_top-relative-expression-ranked_200

EPB41L5 PPARGC1A VAV3 NFAT5

2.47e-04541204gudmap_developingKidney_e15.5_cortic collect duct_200_k3
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000_k-means-cluster#4

MECOM PPARGC1A FEZ1 CLTB NRG3 ATP1B2 CDH8

2.79e-042231207Facebase_RNAseq_e9.5_Facial Mesenchyne_1000_K4
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#2_top-relative-expression-ranked_500

ZNF518A SYCP2 BRCA2 BRDT

2.84e-04561204gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k2_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500_k-means-cluster#2

MECOM PPARGC1A FEZ1 NRG3 CDH8

2.98e-041031205Facebase_RNAseq_e8.5_Paraxial Mesoderm_500_K2
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_500

SMG1 EPB41L5 PPARGC1A VPS13A VAV3 NFAT5

3.31e-041631206gudmap_developingKidney_e15.5_cortic collect duct_500_k4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#4

CDV3 EPB41L5 TENM2 LDLR VPS13A ELAVL2 CDH8

3.46e-042311207Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K4
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#4

MECOM PPARGC1A FEZ1 CLTB NRG3 ATP1B2 CDH8

3.55e-042321207Facebase_RNAseq_e9.5_Maxillary Arch_1000_K4
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29965_top-relative-expression-ranked_1000

PTBP3 STAB2 EVI2B AQP1 ZEB2 STAB1 EHBP1L1 SAMD9L PTPRC HLTF VAV3 PEAK1 NFAT5

3.74e-0476112013gudmap_developingKidney_e15.5_Endothelial cells_1000
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_500

SMG1 EPB41L5 PPARGC1A SAMD9L VPS13A HLTF VAV3 NFAT5 SORL1

3.78e-043901209gudmap_developingKidney_e15.5_cortic collect duct_500
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 CDV3 MBNL1 ZEB2 SAMD9L PTPRC SCAF11 PLCG2 ZNF292

4.47e-09200122912f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

EPB41L5 MECOM SLC1A1 PPARGC1A SHANK2 NAV2 NRG3 AKAP7

2.82e-081741228548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EPB41L5 MECOM SLC1A1 PPARGC1A SHANK2 NAV2 PEAK1 NRG3

4.35e-08184122857c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EPB41L5 MECOM SLC1A1 PPARGC1A SHANK2 NAV2 PEAK1 NRG3

4.35e-081841228d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

MON2 SMG1 MBNL1 LDLR ZEB2 PTPRC ARIH1 NFAT5

5.13e-081881228ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellIPF-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

RBMS2 ZEB2 NEO1 ANTXR1 TMEM108 RXFP1 NRG3 ADAMTSL2

7.08e-0819612288f0f72ead06abe02b575e443552eacc2151077ef
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 MBNL1 AQP1 PTPRC VPS13A PLCG2 MED23 ZNF292

7.36e-08197122857ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 PTBP3 OLFM4 PPARGC1A PTPN13 CLU NFAT5 TBX2

7.96e-0819912283cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHIA AOX1 MECOM LDLR BRCA2 CLU BUB1B

3.85e-071661227575c325db88d6909cdf0d5e664bd9098b89d4401
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

EPB41L5 MECOM LDLR SHANK2 NAV2 NRG3 AKAP7

4.52e-071701227e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 OLFM4 MECOM PPARGC1A PTPN13 CLU CST6

7.69e-0718412279690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCellControl-Epithelial-Club|World / Disease state, Lineage and Cell class

EPB41L5 MECOM LDLR PTPN13 SHANK2 NAV2 TMEM108

8.27e-0718612279798428691408e17ff2af2fe2d1b345f074d67e4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 OLFM4 MECOM PPARGC1A PTPN13 CLU TBX2

8.27e-071861227b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 MECOM CA10 PPARGC1A RANBP3L TMEM108 VAV3

8.88e-071881227bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

EPB41L5 MECOM SLC1A1 LDLR PTPN13 SHANK2 NAV2

8.88e-071881227c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellkidney_cells-Hypertensive_with+without-CKD|kidney_cells / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 MECOM PTPN13 RANBP3L CLU NFAT5 SORL1

8.88e-07188122790188b60ff893754f7938fe8edab79758827168e
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

EPB41L5 MECOM SLC1A1 LDLR PTPN13 SHANK2 AGBL1

8.88e-071881227707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 MECOM CA10 PPARGC1A RANBP3L RALGPS1 NAV2

9.20e-071891227f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTBP3 CDV3 APOB ZNF518A SAMD9L SCAF11 ARHGAP20

9.88e-07191122760c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellAdult-Immune-monocyte-D175|Adult / Lineage, Cell type, age group and donor

ZNF804A ZEB2 STAB1 EHBP1L1 PTPRC VAV3 PLCG2

9.88e-071911227cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTBP3 CDV3 APOB ZNF518A SAMD9L SCAF11 ARHGAP20

9.88e-07191122709db184cb90fe282a14474d7217068c58092c6f8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MECOM CA10 PPARGC1A SHANK2 RANBP3L RALGPS1 NAV2

9.88e-071911227963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

EPB41L5 MECOM SLC1A1 PTPN13 SHANK2 NAV2 AKAP7

9.88e-071911227d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTBP3 CDV3 APOB ZNF518A SAMD9L SCAF11 ARHGAP20

9.88e-071911227973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

EPB41L5 MECOM LDLR PTPN13 SHANK2 NAV2 AGBL1

1.02e-061921227499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

MON2 SMG1 MBNL1 LDLR PTPRC ARIH1 SORL1

1.02e-06192122747646d7e4990be85072987f92bf18d52f8da752e
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

ZEB2 STAB1 PTPRC BRCA2 BUB1B MKI67 VAV3

1.02e-061921227a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

EPB41L5 MECOM LDLR PTPN13 SHANK2 NAV2 AGBL1

1.02e-061921227efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

ZEB2 STAB1 PTPRC BRCA2 BUB1B MKI67 VAV3

1.06e-06193122712bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

MON2 MBNL1 UBE2B SCAF11 PLCG2 NFAT5 ZNF292

1.06e-061931227e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 OLFM4 PPARGC1A PTPN13 VAV3 ATP1B2 TBX2

1.13e-0619512273f517c6fc372bdcaf45b3af373414f13cbebd4ba
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TENM2 ZEB2 NEO1 ANTXR1 TMEM108 ARHGAP20 TBX2

1.13e-0619512270e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPB41L5 MECOM PPARGC1A PTPN13 SHANK2 RALGPS1 VAV3

1.13e-0619512276477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EPB41L5 MECOM SLC1A1 LDLR PTPN13 SHANK2 NAV2

1.13e-0619512279406866f99555198a9be311fbd65751b70f35446
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 NEK10 MECOM PTPN13 SHANK2 VAV3 SORL1

1.17e-061961227c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPB41L5 MECOM PPARGC1A PTPN13 SHANK2 RALGPS1 VAV3

1.17e-061961227eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

EPB41L5 MECOM PTPN13 SHANK2 NAV2 PEAK1 AGBL1

1.26e-0619812271996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 OLFM4 PPARGC1A ELAVL2 PLCG2 CDH8

2.16e-06137122681cdb216e6c81acf9c2072f9d39e1a42612e1258
ToppCellLPS-antiTNF-Endothelial-Mes-Like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NEK10 EVI2B ACOX2 PPARGC1A ADAMTSL2 TBX6

4.93e-06158122650df52d64d07178975563abd98ce4fddb9f2f7ef
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MECOM CA10 PPARGC1A RANBP3L RALGPS1 VAV3

5.29e-06160122603b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE6A ODC1 AQP1 UBE2B RALGPS1 RNF10

5.69e-06162122608ee7ae56e4927874515c47adc86dd845bf29a26
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPB41L5 MECOM PTPN13 SHANK2 TMEM108 AKAP7

6.54e-061661226c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 PTPN13 SHANK2 MKI67 TMEM108 CEP152

7.00e-061681226a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell367C-Fibroblasts-Fibroblast-G-|367C / Donor, Lineage, Cell class and subclass (all cells)

APOB NEO1 RANBP3L ANTXR1 ELAVL2 TBX2

7.00e-061681226b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCellControl|World / group, cell type (main and fine annotations)

EPB41L5 MECOM LDLR SHANK2 NAV2 AGBL1

7.00e-061681226a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell367C-Fibroblasts-Fibroblast-G|367C / Donor, Lineage, Cell class and subclass (all cells)

APOB NEO1 RANBP3L ANTXR1 ELAVL2 TBX2

7.00e-0616812268c95093b1ea45826f62893edd3c410fe53b563a4
ToppCellTCGA-Prostate-Solid_Tissue_Normal-Prostate_normal_tissue-Prostate_normal_tissue-4|TCGA-Prostate / Sample_Type by Project: Shred V9

AOX1 ZNF804A ACOX2 PPARGC1A TMEM108 ARHGAP20

7.75e-061711226cafcb7714110cb361808dbe4b9a4963bb71f5129
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SMG1 MBNL1 APOB LDLR PTPRC ARIH1

7.75e-0617112262e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellfacs-Aorta-Heart-3m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVI2B ITGB7 PTPRC MKI67 GPR171 PLCG2

8.28e-061731226513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCellfacs-Heart-RA-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDV3 EP400 LDLR RNF10 TRIM8 VAV3

9.74e-061781226b505e2550860e777535ee95f29c936242fd607f1
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC CST6 NAV2 TMEM108 PLCG2 AGBL1

9.74e-06178122609a215a0d6e98e4bb920cabda12af08ff4de3c98
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SMG1 MUC16 LDLR FER1L6 PLCG2 SORL1

1.01e-0517912266e965e424eebef50f0202cff75f458be395cfca1
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPB41L5 MECOM SLC1A1 SHANK2 NAV2 AKAP7

1.01e-051791226cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellfacs-Aorta-Heart-3m-Myeloid-macrophage|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVI2B ITGB7 PTPRC MKI67 GPR171 PLCG2

1.11e-051821226df26388c0c46d1c4775103c8e802937b4d4e7470
ToppCellfacs-Aorta-Heart-3m-Myeloid-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVI2B ITGB7 PTPRC MKI67 GPR171 PLCG2

1.14e-051831226062ec08d66c923f90fee771b1bf8d98bdc7e6c1b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 SLC1A1 PPARGC1A NAV2 VAV3 ATP1B2

1.14e-0518312262f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 MBNL1 ZEB2 SAMD9L PTPRC SCAF11

1.18e-0518412261154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

EPB41L5 MECOM PTPN13 SHANK2 TMEM108 AGBL1

1.21e-051851226673f0c688ae6984bc8027df2da335787924f4137
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPB41L5 MECOM PTPN13 SHANK2 TMEM108 AGBL1

1.21e-05185122698b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

MON2 LDLR ZEB2 PTPRC NFAT5 ZNF292

1.21e-051851226a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 ZEB2 SAMD9L PTPRC SCAF11 VAV3

1.21e-0518512267adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 MECOM LDLR PPARGC1A PTPN13 TBX2

1.25e-051861226d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 MECOM LDLR PPARGC1A PTPN13 TBX2

1.25e-05186122608632045d499e61dd96ff29a5a9a208afe58dc58
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MECOM LDLR PTPN13 NAV2 AGBL1 AP3D1

1.25e-051861226acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellCOPD-Epithelial-Club|World / Disease state, Lineage and Cell class

EPB41L5 MECOM LDLR PTPN13 SHANK2 NAV2

1.25e-0518612263006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCellfacs-Skin-Telogen-3m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDV3 LDLR CLU RASSF1 ANTXR1 MAP2K3

1.29e-0518712269c1013720c248ef201d010806b6e7ad24205e8ee
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

FEZ1 NAV2 TMEM108 ARHGAP20 ADAMTSL2 TBX2

1.29e-051871226e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MECOM CA10 PPARGC1A RANBP3L RALGPS1 NAV2

1.29e-0518712267ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LDLR ZEB2 PTPN13 TMEM108 ARHGAP20 TBX2

1.29e-051871226a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MECOM CA10 PPARGC1A RANBP3L RALGPS1 NAV2

1.33e-0518812262ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 MECOM CA10 PPARGC1A RANBP3L VAV3

1.33e-051881226eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 PTBP3 MECOM PTPN13 NFAT5 TBX2

1.37e-05189122690aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 MECOM CA10 PPARGC1A NAV2 TMEM108

1.37e-051891226975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 MECOM CA10 PPARGC1A NAV2 TMEM108

1.37e-0518912267eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

MECOM PPARGC1A PTPN13 RANBP3L VAV3 NFAT5

1.37e-051891226830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

EPB41L5 MECOM PTPN13 SHANK2 NAV2 TMEM108

1.37e-051891226f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 MECOM CA10 PPARGC1A RANBP3L RALGPS1

1.41e-051901226b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellControl-Lymphoid-NK|Lymphoid / Disease state, Lineage and Cell class

ZEB2 FEZ1 VAV3 PLCG2 NFAT5 SORL1

1.41e-0519012261584c68b58c7f406d9b0e8451beea3e6f8980c56
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 PTBP3 MECOM PPARGC1A PTPN13 TBX2

1.41e-0519012264836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 MECOM PTPN13 PLCG2 NFAT5 TBX2

1.41e-051901226b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPB41L5 SLC1A1 PPARGC1A SHANK2 NAV2 NRG3

1.41e-05190122630b50d183d7649146eb1e79b47ba897355f1998a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MECOM CA10 PPARGC1A RANBP3L RALGPS1 NAV2

1.41e-0519012263dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTBP3 MBNL1 PTPRC MKI67 GPR171 RXFP1

1.45e-051911226912e2d10d3423aa7f708fcf2b11da1845f12d7d3
ToppCellIPF-Epithelial-Club|World / Disease state, Lineage and Cell class

MECOM PPARGC1A PTPN13 SHANK2 NAV2 TMEM108

1.45e-0519112263c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTBP3 MBNL1 PTPRC MKI67 GPR171 RXFP1

1.45e-05191122677a2746b6d9c53b08d4405411c16fcc5a6c734ce
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AOX1 RANBP3L NAV2 ANTXR1 TMEM108 TBX2

1.45e-0519112266688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

MON2 LDLR ZEB2 PTPRC NFAT5 ZNF292

1.45e-0519112269454f642c3621370fa23640b631301346b300950
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EPB41L5 MECOM SLC1A1 SHANK2 NAV2 AGBL1

1.45e-051911226ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

MECOM AQP1 SLC1A1 CLU TMEM108 NRG3

1.50e-051921226c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ZNF804A TENM2 SHANK2 ELAVL2 NRG3 CDH8

1.50e-0519212264c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellcontrol-Lymphoid-Treg|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

EVI2B CA10 ITGB7 ZEB2 PTPRC GPR171

1.50e-0519212269067e90b7c2d734100d6e5026d753113bf9428a3
ToppCellControl-Epithelial-Club|Control / Disease state, Lineage and Cell class

EPB41L5 MECOM PTPN13 SHANK2 NAV2 TMEM108

1.50e-051921226d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCellCOVID-19-kidney-CNT|kidney / Disease (COVID-19 only), tissue and cell type

TRPM6 OLFM4 MECOM PPARGC1A PTPN13 TBX2

1.50e-051921226d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AOX1 RANBP3L NAV2 ANTXR1 TMEM108 TBX2

1.50e-05192122699ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 MECOM PTPN13 CLU TBX2 SORL1

1.50e-051921226d5ec4cdb15620a5abfc83577353501186c2bc86a
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

RBMS2 MECOM SLC1A1 TMEM108 VAV3 NRG3

1.54e-0519312262531266bc57339d4e2b22a88817008e32b8c1598
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 MECOM PTPN13 CLU TBX2 SORL1

1.54e-0519312265da60321bcf761913eb30779b6d8b1e933c5e51e
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

RBMS2 MECOM SLC1A1 TMEM108 VAV3 NRG3

1.54e-05193122601c2df9206f1527c578e808978e58196c35e72f5
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 MBNL1 AQP1 VPS13A PLCG2 ZNF292

1.54e-0519312269337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

AOX1 TENM2 NAV2 TMEM108 ADAMTSL2 TBX2

1.54e-05193122699525545552b371c86b18b6ea6f4897dc6e9a9ec
DrugSuccimer

SMG1 MBTD1 ANPEP AOX1 ZBTB8A MECOM ODC1 RFX7 ZNF804A ITGB7 ZEB2 ZNF518A PTPN11 SAMD9L PTPRC BRCA2 FEZ1 CLU RASSF1 MKI67 NAV2 VAV3 NFAT5 ZNF292 SORL1

9.91e-09126412125ctd:D004113
DrugMagnetite Nanoparticles

SMG1 MBTD1 ANPEP AOX1 ZBTB8A MECOM ODC1 RFX7 ZNF804A ITGB7 ZEB2 ZNF518A PTPN11 SAMD9L PTPRC BRCA2 FEZ1 CLU RASSF1 MKI67 NAV2 VAV3 NFAT5 ZNF292 SORL1

2.01e-08131012125ctd:D058185
Drugmesna

ANPEP MBNL1 OLFM4 AQP1 SHANK2

6.83e-06501215CID000000598
DrugGabazine [105538-73-6]; Down 200; 10.8uM; MCF7; HT_HG-U133A

MBTD1 SYCP2 EHBP1L1 BRCA2 RALGPS1 RASSF1 CEP152 MAP2K3

8.17e-0619012183253_DN
DrugHydrastine hydrochloride [5936-28-7]; Up 200; 9.6uM; PC3; HT_HG-U133A

PTBP3 CDV3 EPB41L5 BRCA2 ARIH2 CLTB AKAP7 TBX2

9.88e-0619512187309_UP
DrugProxyphylline [603-00-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A

PTBP3 MBNL1 ZNF804A BRCA2 FEZ1 ELAVL1 CDH8 AKAP7

1.06e-0519712186494_DN
DrugLoperamide hydrochloride [34552-83-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A

PLXNA3 PTBP3 ALPK1 SYCP2 EHBP1L1 RASSF1 CLTB NFAT5

1.10e-0519812181533_DN
DrugProcaine hydrochloride [51-05-8]; Down 200; 14.6uM; HL60; HT_HG-U133A

PTBP3 TCTN3 MBTD1 EP400 ALPK1 ZNF804A LDLR MAP2K3

1.10e-0519812181838_DN
Diseasemagnesium measurement

TRPM6 MECOM ALPK1 SKOR2 ELAVL2

7.81e-06661215EFO_0004845
Diseaselate-onset Alzheimers disease

NEK10 CEP295NL AOX1 MECOM SHANK2 CLU PLCG2 SORL1

2.86e-052921218EFO_1001870
Diseaseovarian cancer (is_implicated_in)

MUC16 APOB BRCA2 RASSF1

8.38e-05561214DOID:2394 (is_implicated_in)
DiseaseMuckle-Wells Syndrome

ZEB2 PLCG2

1.65e-0451212C0268390
Diseasealcohol consumption measurement

ENTHD1 ALPK1 ZNF804A TENM2 BRDT RALGPS1 ARIH2 ELAVL2 SCAF11 PEAK1 NFAT5 AGBL1 CCDC33 SORL1 TBX6

1.75e-04124212115EFO_0007878
DiseaseProstate cancer, familial

MBNL1 MECOM RFX7 BRCA2

1.89e-04691214C2931456
DiseaseSeizures

PIGP SLC1A1 CLU TRIM8 AP3D1 ZNF292

2.88e-042181216C0036572
DiseaseLDL cholesterol change measurement

APOB LDLR

3.46e-0471212EFO_0007804
Diseaseatherosclerosis (implicated_via_orthology)

LDLR CLU

3.46e-0471212DOID:1936 (implicated_via_orthology)
Diseasebreast cancer (is_implicated_in)

PTPN13 BRCA2 CLU RASSF1 MKI67

3.93e-041501215DOID:1612 (is_implicated_in)
Diseasethalamus volume

RFX7 PPARGC1A NAV2 NFAT5

4.22e-04851214EFO_0006935
Diseasenon-alcoholic fatty liver disease (implicated_via_orthology)

PPARGC1A UBE2A UBE2B

4.35e-04361213DOID:0080208 (implicated_via_orthology)
Diseasechronic kidney disease, diabetic nephropathy

TENM2 PTPN13 NRG3

4.35e-04361213EFO_0000401, EFO_0003884
DiseaseGrowth Disorders

BUB1B SECISBP2 ADAMTSL2

4.35e-04361213C0018273
Diseasecerebellar ataxia (implicated_via_orthology)

GEMIN5 VPS13A

4.59e-0481212DOID:0050753 (implicated_via_orthology)
DiseaseFamilial hypercholesterolemia

APOB LDLR

4.59e-0481212cv:C0020445
DiseaseMental deterioration

CLU SORL1

5.89e-0491212C0234985
DiseaseMild cognitive disorder

CLU SORL1

5.89e-0491212C1270972
Diseasemyocardial infarction

APOB CA10 LDLR ZEB2 EHBP1L1 PLCG2 AP3D1

6.18e-043501217EFO_0000612
Diseasemean corpuscular hemoglobin concentration

EP400 MECOM ENTHD1 ZEB2 NEO1 EHBP1L1 PTPRC BRDT VPS13A ANTXR1 MAP2K3 AKAP7 TBX6

6.20e-04110512113EFO_0004528
DiseaseColorectal Carcinoma

APOB ODC1 ZNF804A ZEB2 CABYR BUB1B VPS13A MKI67 ZNF292 SORL1

6.45e-0470212110C0009402
Diseaseproteinuria (biomarker_via_orthology)

ZEB2 CLU

7.35e-04101212DOID:576 (biomarker_via_orthology)
Diseaseresponse to carboplatin, response to antineoplastic agent

AKNAD1 PLCG2

7.35e-04101212GO_0097327, GO_0097328
Diseasefamilial hypercholesterolemia (is_implicated_in)

APOB LDLR

7.35e-04101212DOID:13810 (is_implicated_in)
DiseaseAtrophic

SLC1A1 CLU

7.35e-04101212C0333641
DiseaseAlzheimer disease

TENM2 CLU CST6 CSTB ANTXR1 PLCG2 ARHGAP20 SORL1

8.96e-044851218MONDO_0004975
Diseasesystemic lupus erythematosus (is_marker_for)

LDLR CLU MKI67

9.56e-04471213DOID:9074 (is_marker_for)
DiseaseProstatic Neoplasms

STAB2 PIGP AOX1 PTPRC BRCA2 CLU CST6 VAV3 ZNF292

1.01e-036161219C0033578
DiseaseMalignant neoplasm of prostate

STAB2 PIGP AOX1 PTPRC BRCA2 CLU CST6 VAV3 ZNF292

1.01e-036161219C0376358
Diseasered blood cell density measurement

EP400 MBNL1 EPB41L5 MECOM RFX7 ZEB2 PPARGC1A PTPRC ANTXR1 AP3D1 TBX6

1.01e-0388012111EFO_0007978
Diseaseurate measurement, bone density

TRPM6 CA10 TENM2 PPARGC1A ARIH2 ELAVL2 VWA3B TMEM108 PEAK1

1.05e-036191219EFO_0003923, EFO_0004531
Diseaseforced expiratory volume, traffic air pollution measurement

CA10 NAV2

1.07e-03121212EFO_0004314, EFO_0007908
Diseasereticulocyte count

GEMIN5 PTPN11 PTPRC RANBP3L RASSF1 DNAH17 VPS13A RNF10 ANTXR1 PLCG2 MAP2K3 TBX6

1.24e-03104512112EFO_0007986
DiseaseHyperlipoproteinemia Type IIb

APOB LDLR

1.26e-03131212C1704417
Diseaselow density lipoprotein cholesterol measurement, lipid measurement

APOB LDLR PTPN11 BRCA2

1.27e-031141214EFO_0004529, EFO_0004611
Diseasesusceptibility to bacterial meningitis measurement

CA10 NFAT5 AKAP7

1.28e-03521213EFO_0008411
Diseaselung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma

NEK10 MECOM BRCA2

1.28e-03521213EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575
Diseaseobsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa

OLFM4 ENTHD1 ZNF804A TENM2 TRIM8

1.43e-032001215EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351
DiseaseImpaired cognition

CLU SORL1

1.47e-03141212C0338656
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

APOB LDLR

1.47e-03141212EFO_0004611, EFO_0008589
Diseasememory performance

MECOM LDLR STAB1 NEO1 VAV3 AGBL1 SORL1

1.52e-034091217EFO_0004874
Diseaselow density lipoprotein cholesterol measurement, phospholipid measurement

APOB LDLR PTPN11 BRCA2

1.53e-031201214EFO_0004611, EFO_0004639
Diseaseresponse to statin, LDL cholesterol change measurement

APOB LDLR

1.69e-03151212EFO_0007804, GO_0036273
Diseasecholesteryl ester measurement, low density lipoprotein cholesterol measurement

APOB LDLR PTPN11 BRCA2

1.83e-031261214EFO_0004611, EFO_0010351
Diseaseadverse effect, response to xenobiotic stimulus

STAB2 NAV2 VWA3B

1.85e-03591213EFO_0009658, GO_0009410
Diseasedepressive symptom measurement

MBNL1 OLFM4 ZNF804A TENM2 STAB1 PPARGC1A ELAVL2

1.92e-034261217EFO_0007006
DiseaseHyperlipoproteinemia Type IIa

APOB LDLR

1.93e-03161212C0745103
Diseasesyndromic intellectual disability (implicated_via_orthology)

UBE2A UBE2B

1.93e-03161212DOID:0050888 (implicated_via_orthology)
DiseaseSchizoaffective disorder-bipolar type

STAB2 ZNF804A

1.93e-03161212EFO_0009965
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

PIGP TRIM8

1.93e-03161212C0393706
DiseasePROSTATE CANCER, HEREDITARY, 1

MBNL1 MECOM RFX7

1.94e-03601213C4722327
DiseaseLipidemias

APOB LDLR

2.18e-03171212C1706412
Diseaserespiratory symptom change measurement, response to placebo

PPARGC1A NAV2

2.18e-03171212EFO_0008344, EFO_0010068
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

RFX7 ZNF292

2.18e-03171212DOID:0060307 (is_implicated_in)
DiseaseHyperlipidemia

APOB LDLR

2.18e-03171212C0020473
Diseaseovarian neoplasm

MUC16 MECOM BRCA2 MKI67

2.29e-031341214C0919267
DiseaseFeeding difficulties

PIGP ZNF292

2.44e-03181212C0232466
DiseaseHypercholesterolemia, Familial

APOB LDLR

2.44e-03181212C0020445
DiseaseMalignant neoplasm of ovary

MUC16 MECOM BRCA2 MKI67

2.48e-031371214C1140680
DiseaseIntellectual Disability

PIGP ODC1 SHANK2 TRIM8 CSTB MED23 ZNF292

2.51e-034471217C3714756
Diseasecarotid artery intima media thickness

APOB BOD1L2 ZNF804A TENM2 NAV2 SPATA22 CDH8

2.61e-034501217EFO_0007117
DiseaseMYELODYSPLASTIC SYNDROME

MECOM PTPN11 BRCA2

2.66e-03671213C3463824
Diseasesodium-coupled monocarboxylate transporter 1 measurement

APOB LDLR

2.72e-03191212EFO_0802076
DiseaseMalignant neoplasm of urinary bladder

ANPEP BRCA2 RALGPS1 RASSF1

2.76e-031411214C0005684
Diseasehematocrit

LYPLAL1 RBMS2 MBNL1 EPB41L5 MECOM APOB STAB1 PPARGC1A NFAT5 AP3D1 TBX6

3.00e-03101112111EFO_0004348
Diseasecholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage

APOB LDLR

3.33e-03211212EFO_0022246
Diseasecortical surface area measurement

MON2 TRPM6 MECOM TENM2 NEO1 RALGPS1 TRIM8 NAV2 ELAVL2 MED23 AGBL1 CCDC33 TBX6

3.54e-03134512113EFO_0010736
Diseasediet measurement, fasting blood insulin measurement

NRG3 AGBL1

3.65e-03221212EFO_0004466, EFO_0008111
Diseaseclinical and behavioural ideal cardiovascular health

LDLR NFAT5

3.99e-03231212EFO_0007654
Diseasediet measurement, HOMA-IR

NRG3 AGBL1

3.99e-03231212EFO_0004501, EFO_0008111
Diseasegut microbiome measurement, bone density

TCTN3 IMPG1 PPARGC1A

4.09e-03781213EFO_0003923, EFO_0007874

Protein segments in the cluster

PeptideGeneStartEntry
DPYDCNKNNQALKIV

BUB1B

896

O60566
QNQKYQGTVKPTFRN

CEP295NL

431

Q96MC4
QQKVAYAAQPALKTQ

EP400

3006

Q96L91
KVLDYQTQQQKLFPQ

ACOX2

336

Q99424
NKVTYKPYQSSAQNN

CEP152

191

O94986
AQKLANQASNYAESP

nan

491

Q9N2J8
RVKNNQPAKYPLNNA

ANTXR1

486

Q9H6X2
QAQQPQAALLKQYQG

CCDC33

731

Q8N5R6
KNVLPDSQQQYNVVK

BRDT

251

Q58F21
AVQQYLEETQNKNKP

AKAP7

311

Q9P0M2
KPAYQNLSQKADNFV

BOD1L2

66

Q8IYS8
QFNRPFNEAASKNKQ

C4orf47

31

A7E2U8
KYPVGNNQTAVQDNV

AQP1

36

P29972
LYQAFNGLKNKNSQL

CHIA

76

Q9BZP6
ENKPLTLSNYQTNKA

CSTB

76

P04080
LKTNPSNINQFAAAY

CABYR

26

O75952
NQSQQAQAREALKKY

ARIH2

351

O95376
VVYSQEKNKNANSSP

ANPEP

31

P15144
YQDSPNQKKRTNGLQ

DCP2

326

Q8IU60
SKNQALKLQLDNQYA

CDV3

231

Q9UKY7
KNDYEKFKNNPQINL

ALPK1

251

Q96QP1
KKNPGVNLYQNVQSN

AGBL1

431

Q96MI9
ARKQEQANNPFYIKS

AP3D1

671

O14617
QTPYKQEINAKNLIQ

AOX1

961

Q06278
YNRNNKKPYVSLAQQ

RBMS2

16

Q15434
QKIKEYNAQINSNLF

RASSF1

141

Q9NS23
QLNNPDKGNVYKFQT

RALGPS1

511

Q5JS13
LQNLASINNKKEYSN

MECOM

626

Q03112
YLKKNNQSIIFENNQ

ARIH1

481

Q9Y4X5
QIQEQLKVPQNGKSY

NRG3

391

P56975
VINKAYQKPAQSSIQ

ENTHD1

381

Q8IYW4
QDKAQPGTTNYQRNK

MUC16

14336

Q8WXI7
QYQATLQNQAKTKAA

MBTD1

121

Q05BQ5
QAYKTSVKKFQNQQN

IMPG1

756

Q17R60
NKFLEPYNDSIQAQK

ATP1B2

111

P14415
AKNLPQPQSGQKNYE

PLXNA3

706

P51805
ENIESINQNKAPLKY

NEK10

501

Q6ZWH5
KPSEDIYKNWQQQQQ

FAM157A

61

C9JC47
KSPNLSEIKFNSYNN

PEAK1

586

Q9H792
TNNLYQMKSQNPLAK

PDE6A

606

P16499
LDTTSNKQTPQKNNY

EVI2B

186

P34910
NKQTPQKNNYNSIAA

EVI2B

191

P34910
DNENYPNVKKALINI

GPR171

211

O14626
NNVPQESRFNLKKNV

MED23

746

Q9ULK4
YASLDPLNIKQNNKQ

EHBP1L1

1086

Q8N3D4
NGNYKVDSPKNFNIA

ADAMTSL2

266

Q86TH1
NYNAKTENLAPVKNQ

FEZ1

76

Q99689
TEQNNSSQPSKQKYV

LRRC42

401

Q9Y546
VKFAANPNQNKNVAL

ELAVL1

181

Q15717
NPNQNKNVALLSQLY

ELAVL1

186

Q15717
KTPVQYSQQQNSPQK

MKI67

346

P46013
YSQQQNSPQKHKNKD

MKI67

351

P46013
NTYNVVKAPQGKNQK

PLCG2

856

P16885
QENKNKNRYKNILPF

PTPN11

271

Q06124
ANAKYNQIQLFAPAE

MON2

1386

Q7Z3U7
PSENEKQQQIQPKAY

NFAT5

656

O94916
KPADAAQYLQQQAKL

FOXB1

121

Q99853
QQLNWKQDSNPLYKS

ITGB7

766

P26010
SNQYNNEPSNIFEKI

PPARGC1A

66

Q9UBK2
SDKFYKQTVNLQLQP

APOB

1776

P04114
QTPAQAETNYLNKAK

EPB41L5

211

Q9HCM4
ISNVKDANAYPQTVN

BRCA2

1791

P51587
KYLNFQQQKEIPDSA

DNAH17

686

Q9UFH2
NDLNKINPVYQFSLK

DNAH17

3666

Q9UFH2
NAKIAYKQNKANTAQ

GJC1

306

P36383
QSVFKEPNNENKNAL

GOLGA8J

371

A6NMD2
KSYQGQSPQKQQTEK

AKNAD1

226

Q5T1N1
KFANNPSQKTNQAIL

ELAVL2

201

Q12926
KIKAAQYQVNQAAAA

MBNL1

246

Q9NR56
LNKASAVYQALQKSN

LYPLAL1

151

Q5VWZ2
NKDKTDLPQSVVYQN

CEP192

461

Q8TEP8
PQVQKAAQAAVASYN

CST6

46

Q15828
PSSNQNVNSKVNKYY

EEF2K

46

O00418
NPYDKNAIKVNNVNG

HLTF

91

Q14527
NNPNFTIKKNEDNSL

CDH8

541

P55286
QGKDCPNNRAQKLQY

CA10

306

Q9NS85
SQQVNYIASQPDGKQ

SCAF11

1286

Q99590
NQQQKKYQEEAIPAL

PIGP

121

P57054
ANPCKQVSQIKYAAN

ODC1

111

P11926
PENLVQACFQQYKTK

SLC1A1

151

P43005
SLYQPLQNSSKEKND

PTPN13

941

Q12923
INPELNQKGYNVKSD

MAP2K3

236

P46734
IQSYKNNPNFSIQAD

FER1L6

1031

Q2WGJ9
SQKDEDYLKQNQPLQ

ARHGAP20

736

Q9P2F6
PQGYQLKNNTCVKQE

SORL1

1061

Q92673
ALQTLKPNFQQNQYK

SPATA22

196

Q8NHS9
VNEYAFLLQQNSKKP

SAMD9L

1361

Q8IVG5
AALQAQKAQDSYQTP

SMG1

2226

Q96Q15
KTNIPANTKYKNANA

NEO1

896

Q92859
SLSRYKQQQQQPQKQ

NAV2

186

Q8IVL1
KFQSKQQPQDNFKNN

SECISBP2

426

Q96T21
SKNKPVLNAFNQYEA

TENM2

1571

Q9NT68
KNNAYLAQSPQLYKQ

DARS1

241

P14868
EKVQSINYNPFDQKL

OLFM4

476

Q6UX06
NKELKNYNSQTPFQV

SHANK2

356

Q9UPX8
KSIYQVENLKQPFQS

BTG4

166

Q9NY30
KINNRIADKAFYQQP

CLTB

151

P09497
NQGSKYVNKEIQNAV

CLU

36

P10909
QQPTDSLNNDNKYSL

USP22

451

Q9UPT9
EKAFNQFPNLTRQNK

ZNF846

176

Q147U1
KNVPDLKSTYNNVLQ

VPS13A

971

Q96RL7
NKYNYHPASQKNTQQ

ZBTB8A

181

Q96BR9
AAQKLIYTFNQVKPQ

TRPM6

1836

Q9BX84
YQNDKITQLKIDNNP

TBX2

266

Q13207
QKLTQPQLENDSYAK

RANBP3L

226

Q86VV4
QQNHPKYSGQKNTEN

SYCP2

696

Q9BX26
KRELSYPKNESFNNQ

RNF10

66

Q8N5U6
QKLQNIKYPSATNNT

GEMIN5

1181

Q8TEQ6
KANNLNTPNNGKFVY

ZNF292

1141

O60281
PANSQAAQLYQENKR

UBE2A

121

P49459
LSYNPIQKIQANQFD

RXFP1

326

Q9HBX9
KDQPQQTFNIYKANN

STAB1

466

Q9NY15
APNNNAIENYIREKK

STAB2

1176

Q8WWQ8
AYQNPQITQLKIAAN

TBX6

251

O95947
QTAFPNALQKQANSK

RFX7

1136

Q2KHR2
KLVQNSTYQNIQPKK

ZNF518A

1121

Q6AHZ1
KNNQFQALLQYADPV

PTBP3

216

O95758
QPSYKDSQKTKENNQ

SKOR2

866

Q2VWA4
KNYANKAPGEQQKLQ

VWA3B

1006

Q502W6
KQANPRRKNVVNYDN

ZEB2

16

O60315
NSNLNYFQKLQKVNA

TCTN3

166

Q6NUS6
NQAYNQKPGLEKNLK

TRIM8

56

Q9BZR9
EENKSKNRNSNVIPY

PTPRC

966

P08575
ASTYPAQNGQVKKNN

PTPRC

1226

P08575
PANSQAAQLYQENKR

UBE2B

121

P63146
KKTANPENNLSYWNN

TMEM108

496

Q6UXF1
DPESANNYTAKNNQV

ZNF804A

186

Q7Z570
DLQQYKIANNPTTDK

VAV3

446

Q9UKW4
KNINSINFDNPVYQK

LDLR

816

P01130