Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglutamine-fructose-6-phosphate transaminase (isomerizing) activity

GFPT1 GFPT2

6.06e-0521562GO:0004360
GeneOntologyMolecularFunctionSAM domain binding

DGKH SAMD11

1.81e-0431562GO:0032093
GeneOntologyMolecularFunctionL-glutamine aminotransferase activity

GFPT1 GFPT2

1.81e-0431562GO:0070548
GeneOntologyMolecularFunctionamino acid binding

CEP104 CAD SHMT2 GRIK1 GFPT1

2.67e-04731565GO:0016597
Domain-

SEMA6B DMXL1 GNB4 ELP2 LRBA WDR1 MAPKBP1 GNB1 GNB2 WDR13 PLRG1 BTRC PLXNA1 DCAF7

5.47e-07333151142.130.10.10
DomainWD40/YVTN_repeat-like_dom

SEMA6B DMXL1 GNB4 ELP2 LRBA WDR1 MAPKBP1 GNB1 GNB2 WDR13 PLRG1 BTRC PLXNA1 DCAF7

5.88e-0733515114IPR015943
DomainWD40

DMXL1 GNB4 ELP2 LRBA WDR1 MAPKBP1 GNB1 GNB2 WDR13 PLRG1 BTRC DCAF7

1.33e-0625915112PF00400
DomainWD40

DMXL1 GNB4 ELP2 LRBA WDR1 MAPKBP1 GNB1 GNB2 WDR13 PLRG1 BTRC DCAF7

1.91e-0626815112SM00320
DomainWD40_repeat

DMXL1 GNB4 ELP2 LRBA WDR1 MAPKBP1 GNB1 GNB2 WDR13 PLRG1 BTRC DCAF7

2.22e-0627215112IPR001680
DomainWD_REPEATS_1

DMXL1 GNB4 ELP2 LRBA WDR1 MAPKBP1 GNB1 GNB2 WDR13 PLRG1 BTRC DCAF7

2.79e-0627815112PS00678
DomainWD_REPEATS_2

DMXL1 GNB4 ELP2 LRBA WDR1 MAPKBP1 GNB1 GNB2 WDR13 PLRG1 BTRC DCAF7

2.89e-0627915112PS50082
DomainWD_REPEATS_REGION

DMXL1 GNB4 ELP2 LRBA WDR1 MAPKBP1 GNB1 GNB2 WDR13 PLRG1 BTRC DCAF7

2.89e-0627915112PS50294
DomainGuanine_nucleotide-bd_bsu

GNB4 GNB1 GNB2

5.12e-0651513IPR016346
DomainWD40_repeat_dom

DMXL1 GNB4 ELP2 LRBA WDR1 MAPKBP1 GNB1 GNB2 WDR13 PLRG1 BTRC DCAF7

5.49e-0629715112IPR017986
DomainARM-like

CEP104 RIPOR2 SARM1 ARFGEF1 MEI1 RIF1 PELP1 LRBA HECTD1 TBCD XPO7

1.27e-0527015111IPR011989
DomainARM-type_fold

CEP104 RIPOR2 SARM1 ARFGEF1 MEI1 ITPR1 RIF1 PELP1 LRBA HECTD1 TBCD XPO7

2.07e-0533915112IPR016024
DomainGprotein_B

GNB4 GNB1 GNB2

5.96e-05101513IPR001632
DomainAnnexinVIII

ANXA8L1 ANXA8

6.49e-0521512IPR009115
DomainGlmS_trans

GFPT1 GFPT2

6.49e-0521512IPR005855
DomainSIS

GFPT1 GFPT2

6.49e-0521512PF01380
DomainG-protein_beta_WD-40_rep

GNB4 WDR1 GNB1 GNB2 PLRG1 BTRC

6.54e-05851516IPR020472
DomainDUF4208

CHD1 CHD2

1.94e-0431512PF13907
DomainSIS

GFPT1 GFPT2

1.94e-0431512PS51464
DomainDUF4208

CHD1 CHD2

1.94e-0431512IPR025260
DomainSIS

GFPT1 GFPT2

1.94e-0431512IPR001347
DomainK_chnl_volt-dep_ELK

KCNH8 KCNH3

1.94e-0431512IPR003950
DomainDUF4208

CHD1 CHD2

1.94e-0431512SM01176
DomainLDLR_class-A_CS

HSPG2 TMPRSS15 SSPOP ST14

2.99e-04401514IPR023415
DomainWD40_repeat_CS

GNB4 WDR1 GNB1 GNB2 PLRG1 BTRC DCAF7

3.79e-041641517IPR019775
Domain-

CEP104 RIPOR2 SARM1 ARFGEF1 RIF1 LRBA HECTD1 TBCD

4.55e-0422215181.25.10.10
DomainLdl_recept_a

HSPG2 TMPRSS15 SSPOP ST14

4.73e-04451514PF00057
Domain-

HSPG2 TMPRSS15 SSPOP ST14

5.15e-044615144.10.400.10
DomainLDLRA_1

HSPG2 TMPRSS15 SSPOP ST14

6.06e-04481514PS01209
DomainBCDHK_Adom3

PDK3 PDK4

6.39e-0451512PF10436
DomainGATASE_TYPE_2

GFPT1 GFPT2

6.39e-0451512PS51278
DomainHis_kinase_dom

PDK3 PDK4

6.39e-0451512IPR005467
DomainHIS_KIN

PDK3 PDK4

6.39e-0451512PS50109
DomainBCDHK/PDK_N

PDK3 PDK4

6.39e-0451512IPR018955
Domain-

PDK3 PDK4

6.39e-04515121.20.140.20
DomainGATase_2_dom

GFPT1 GFPT2

6.39e-0451512IPR017932
DomainLDrepeatLR_classA_rpt

HSPG2 TMPRSS15 SSPOP ST14

6.56e-04491514IPR002172
DomainLDLa

HSPG2 TMPRSS15 SSPOP ST14

6.56e-04491514SM00192
DomainLDLRA_2

HSPG2 TMPRSS15 SSPOP ST14

6.56e-04491514PS50068
DomainSEA

HSPG2 TMPRSS15 ST14

7.13e-04221513PF01390
DomainSEA

HSPG2 TMPRSS15 ST14

8.15e-04231513PS50024
DomainSEA_dom

HSPG2 TMPRSS15 ST14

8.15e-04231513IPR000082
DomainEGF_1

HSPG2 LAMB2 SSPOP STAB1 TENM4 SUSD1 C1S MUC4

1.12e-032551518PS00022
DomainGlyco_hydro_31

MYORG MGAM2

1.33e-0371512IPR000322
DomainGlyco_hydro_31

MYORG MGAM2

1.33e-0371512PF01055
DomainGLYCOSYL_HYDROL_F31_1

MYORG MGAM2

1.33e-0371512PS00129
DomainEGF_2

HSPG2 LAMB2 SSPOP STAB1 TENM4 SUSD1 C1S MUC4

1.43e-032651518PS01186
DomainHelicase_C

CHD1 CHD2 INO80 FANCM DDX18

1.77e-031071515PF00271
DomainHELICc

CHD1 CHD2 INO80 FANCM DDX18

1.77e-031071515SM00490
DomainEGF_LAM_2

HSPG2 LAMB2 STAB1

1.79e-03301513PS50027
DomainEGF_LAM_1

HSPG2 LAMB2 STAB1

1.79e-03301513PS01248
DomainHelicase_C

CHD1 CHD2 INO80 FANCM DDX18

1.85e-031081515IPR001650
DomainHELICASE_CTER

CHD1 CHD2 INO80 FANCM DDX18

1.92e-031091515PS51194
DomainHELICASE_ATP_BIND_1

CHD1 CHD2 INO80 FANCM DDX18

1.92e-031091515PS51192
DomainDEXDc

CHD1 CHD2 INO80 FANCM DDX18

1.92e-031091515SM00487
DomainHelicase_ATP-bd

CHD1 CHD2 INO80 FANCM DDX18

2.00e-031101515IPR014001
DomainSNF2_N

CHD1 CHD2 INO80

2.16e-03321513IPR000330
DomainSNF2_N

CHD1 CHD2 INO80

2.16e-03321513PF00176
DomainAmidohydro_1

CAD AMDHD1

2.80e-03101512PF01979
DomainMetal-dep_hydrolase_composite

CAD AMDHD1

2.80e-03101512IPR011059
DomainPAS_9

KCNH8 KCNH3

2.80e-03101512PF13426
DomainEGF_Lam

HSPG2 LAMB2 STAB1

2.80e-03351513SM00180
DomainLaminin_EGF

HSPG2 LAMB2 STAB1

2.80e-03351513PF00053
DomainDNA/RNA_helicase_DEAH_CS

CHD1 CHD2 FANCM

2.80e-03351513IPR002464
DomainEGF_3

HSPG2 SSPOP STAB1 TENM4 SUSD1 C1S MUC4

3.05e-032351517PS50026
PathwayREACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING

GRIK1 GNB4 GNB1 GNB2

1.19e-04301214M18193
PathwayREACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING

GRIK1 GNB4 GNB1 GNB2

1.54e-04321214MM15143
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 GNB4 GNB1 GNB2

1.54e-04321214MM14983
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 GNB4 GNB1 GNB2

4.49e-04421214M791
PathwayREACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS

ECT2 GNB4 ARHGEF2 GNB1 GNB2

5.17e-04771215MM15044
PathwayREACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR

GNB4 GNB1 GNB2

5.41e-04191213MM15021
PathwayREACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR

GNB4 GNB1 GNB2

5.41e-04191213M926
PathwayREACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS

ECT2 GNB4 ARHGEF2 GNB1 GNB2

6.17e-04801215M800
PathwayREACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42

GNB4 GNB1 GNB2

6.32e-04201213MM15572
PathwayREACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42

GNB4 GNB1 GNB2

6.32e-04201213M27853
PathwayREACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS

GNB4 GNB1 GNB2

7.33e-04211213M27409
PathwayREACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS

GNB4 GNB1 GNB2

7.33e-04211213MM15159
PathwayREACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12

GNB4 GNB1 GNB2

8.43e-04221213MM15016
PathwayREACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12

GNB4 GNB1 GNB2

8.43e-04221213M841
PathwayREACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION

GNB4 GNB1 GNB2

9.64e-04231213MM15033
PathwayKEGG_MEDICUS_REFERENCE_LPAR_GNB_G_RHO_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

9.64e-04231213M47549
PathwayREACTOME_G_PROTEIN_ACTIVATION

GNB4 GNB1 GNB2

1.09e-03241213M13115
PathwayREACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR

GNB4 GNB1 GNB2

1.09e-03241213MM15088
PathwayREACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR

GNB4 GNB1 GNB2

1.09e-03241213M18308
PathwayKEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

1.09e-03241213M47460
PathwayREACTOME_G_PROTEIN_ACTIVATION

GNB4 GNB1 GNB2

1.09e-03241213MM14794
PathwayREACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1

GNB4 GNB1 GNB2

1.24e-03251213MM15056
PathwayREACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1

GNB4 GNB1 GNB2

1.24e-03251213M811
PathwayREACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA

GNB4 GNB1 GNB2

1.24e-03251213M14301
PathwayREACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA

GNB4 GNB1 GNB2

1.39e-03261213MM15017
PathwayKEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

1.39e-03261213M47561
PathwayKEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

1.39e-03261213M47562
PathwayKEGG_MEDICUS_REFERENCE_CCR5_GNB_G_PLCB_G_PKC_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

1.39e-03261213M47557
PathwayKEGG_MEDICUS_REFERENCE_CXCR_GNB_G_PI3K_AKT_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

1.39e-03261213M47456
PathwayREACTOME_PROTEIN_FOLDING

GNB4 GNB1 GNB2 TBCD DCAF7

1.54e-03981215M776
PathwayREACTOME_POTASSIUM_CHANNELS

KCNH8 KCNH3 GNB4 GNB1 GNB2

1.54e-03981215MM14545
PathwayKEGG_MEDICUS_REFERENCE_CXCR_GNB_G_ERK_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

1.55e-03271213M47454
PathwayREACTOME_GPER1_SIGNALING

GNB4 GNB1 GNB2

1.55e-03271213MM15664
PathwayREACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION

GNB4 GNB1 GNB2

1.73e-03281213M10679
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

ITPR1 GNB4 GNB1 GNB2

1.85e-03611214MM15071
PathwayKEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_JNK_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

1.92e-03291213M47466
PathwayREACTOME_POTASSIUM_CHANNELS

KCNH8 KCNH3 GNB4 GNB1 GNB2

1.92e-031031215M1073
PathwayREACTOME_CA2_PATHWAY

ITPR1 GNB4 GNB1 GNB2

1.96e-03621214M27321
PathwayREACTOME_SYNTHESIS_OF_UDP_N_ACETYL_GLUCOSAMINE

GFPT1 GFPT2

1.98e-0381212M27375
PathwayREACTOME_SYNTHESIS_OF_UDP_N_ACETYL_GLUCOSAMINE

GFPT1 GFPT2

1.98e-0381212MM15121
PathwayREACTOME_ACTIVATION_OF_G_PROTEIN_GATED_POTASSIUM_CHANNELS

GNB4 GNB1 GNB2

2.11e-03301213MM14542
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

HTR2A NMUR1 DGKH ITPR1 GNB4 GNB1 GNB2

2.22e-032101217MM15043
PathwayREACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS

GNB4 GNB1 GNB2

2.33e-03311213MM15094
PathwayKEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

2.33e-03311213M47554
PathwayKEGG_MEDICUS_REFERENCE_CCR_CXCR_GNB_G_PI3K_RAC_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

2.33e-03311213M47455
PathwayKEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_ERK_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

2.33e-03311213M47459
PathwayKEGG_MEDICUS_REFERENCE_CCR2_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

2.33e-03311213M47540
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

2.33e-03311213M47541
PathwayREACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS

GNB4 GNB1 GNB2

2.55e-03321213M861
PathwayREACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING

GNB4 GNB1 GNB2

2.55e-03321213M14309
PathwayREACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS

GNB4 GNB1 GNB2

2.55e-03321213MM15148
PathwayKEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM

CAD GFPT1 GFPT2

2.55e-03321213M17758
PathwayKEGG_MEDICUS_REFERENCE_GPCR_PI3K_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

2.55e-03321213M47962
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

HTR2A NMUR1 DGKH ITPR1 GNB4 GNB1 GNB2

2.67e-032171217M18437
PathwayREACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING

GNB4 GNB1 GNB2

2.79e-03331213MM15027
PathwayREACTOME_SIGNAL_AMPLIFICATION

GNB4 GNB1 GNB2

2.79e-03331213MM15020
PathwayREACTOME_G_ALPHA_Z_SIGNALLING_EVENTS

GNB4 GNB1 GNB2

2.79e-03331213MM15058
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY

GNB4 GNB1 GNB2

2.79e-03331213M47550
PathwayREACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS

GNB4 GNB1 GNB2

2.79e-03331213MM15066
PathwayREACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS

GNB4 GNB1 GNB2

2.79e-03331213M10322
PathwayREACTOME_SIGNAL_AMPLIFICATION

GNB4 GNB1 GNB2

2.79e-03331213M9379
PathwayREACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION

GNB4 GNB1 GNB2

2.79e-03331213M11575
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

NPC1 UNC13B SEMA6B HSPG2 LAMB2 INO80 ST14 MYORG KCNH3 MICALL1 PCNX2 SH3TC1 KLHL21 LRBA ARHGEF2 MAPKBP1 HECTD1 PLXNA1 TBCD CD276 BAHCC1

3.78e-0811051592135748872
Pubmed

Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA.

GNB4 GNB1 GNB2

3.74e-07415931543505
Pubmed

The role of G protein beta subunits in the release of ATP from human erythrocytes.

GNB4 GNB1 GNB2

3.74e-074159312512701
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

NPC1 TMEM59 SARM1 ARFGEF1 OSGEP GFPT1 KIDINS220 SLC12A9 ARHGEF2 GNB1 OGA HECTD1 WNK3 TBCD KIF11 SLC27A3 XPO7

1.66e-069421591731073040
Pubmed

Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.

GNB4 GNB1 GNB2

1.86e-066159316371464
Pubmed

Identification of Gnr1p, a negative regulator of G alpha signalling in Schizosaccharomyces pombe, and its complementation by human G beta subunits.

GNB4 GNB1 GNB2

1.86e-066159316884933
Pubmed

The gene for the beta-subunit of retinal transducin (Gnb-1) maps to distal mouse chromosome 4, and related sequences map to mouse chromosomes 5 and 8.

GNB4 GNB1 GNB2

5.16e-06815932328987
Pubmed

Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11.

GNB4 GNB1 GNB2

7.72e-069159310339615
Pubmed

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner.

SLAIN2 MYF6 CAD CHD2 RIF1 SELENOF PLRG1 KIF11

9.01e-06222159835941108
Pubmed

Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.

GNB4 GNB1 GNB2

1.10e-0510159328334111
Pubmed

Expression of olfactory receptors, G-proteins and AxCAMs during the development and maturation of olfactory sensory neurons in the mouse.

GNB4 GNB1 GNB2

1.10e-051015939733924
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

MPST SEMA6B ELOB HSPG2 COL6A2 PDGFRA PDK3 SHMT2 LAMB2 CHD2 GFPT1 ITPR1 NEIL3 GFPT2 GNB1 GNB2 PLXNA1 SLC27A3 DCAF7 XPO7

1.13e-0514511592030550785
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

HSPG2 COL6A2 LAMB2 COL6A5 SSPOP

1.15e-0564159522261194
Pubmed

The G protein subunit gene families.

GNB4 GNB1 GNB2

1.51e-0511159310644457
Pubmed

Specificities of Gβγ subunits for the SNARE complex before and after stimulation of α2a-adrenergic receptors.

GNB4 GNB1 GNB2

1.51e-0511159334932372
Pubmed

A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation.

GNB4 GNB1 GNB2

1.51e-0511159325982117
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

KCNH8 DGKH GRIK1 CHD2 ATP8B1 ZSWIM6 SSPOP PCNX2 PLEKHG4B CCNG2 PPARGC1B KIDINS220 SH3TC1 SH3PXD2A LRBA WDR13 HECTD1 ZDHHC13 TBCD XPO7

1.64e-0514891592028611215
Pubmed

Human Multisubunit E3 Ubiquitin Ligase Required for Heterotrimeric G-Protein β-Subunit Ubiquitination and Downstream Signaling.

GNB4 GNB1 GNB2

2.00e-0512159334342229
Pubmed

Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice.

GNB4 GNB1 GNB2

2.00e-0512159320186915
Pubmed

Differential sensitivity of P-Rex1 to isoforms of G protein betagamma dimers.

GNB4 GNB1 GNB2

2.00e-0512159316301321
Pubmed

Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families.

GNB4 GNB1 GNB2

2.00e-051215938636150
Pubmed

Butyrate elicits a metabolic switch in human colon cancer cells by targeting the pyruvate dehydrogenase complex.

PDK3 PDK4

2.08e-052159220715114
Pubmed

TaqI polymorphisms at the annexin VIII locus (ANX8).

ANXA8L1 ANXA8

2.08e-05215921364010
Pubmed

Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils.

GNB1 GNB2

2.08e-052159220525682
Pubmed

Role of RhoA-specific guanine exchange factors in regulation of endomitosis in megakaryocytes.

ECT2 ARHGEF2

2.08e-052159222387001
Pubmed

The neuronal protein Kidins220/ARMS associates with ICAM-3 and other uropod components and regulates T-cell motility.

ICAM3 KIDINS220

2.08e-052159221381019
Pubmed

Cooperative binding promotes demand-driven recruitment of AnxA8 to cholesterol-containing membranes.

ANXA8L1 ANXA8

2.08e-052159229306076
Pubmed

Therapeutic Potential for CFTR Correctors in Autosomal Recessive Polycystic Kidney Disease.

CFTR PKHD1

2.08e-052159234329764
Pubmed

Bone matrix regulates osteoclast differentiation and annexin A8 gene expression.

ANXA8L1 ANXA8

2.08e-052159221344395
Pubmed

Annexin A8 is up-regulated during mouse mammary gland involution and predicts poor survival in breast cancer.

ANXA8L1 ANXA8

2.08e-052159216203777
Pubmed

The phospholipid flippase ATP8B1 mediates apical localization of the cystic fibrosis transmembrane regulator.

CFTR ATP8B1

2.08e-052159227301931
Pubmed

TBCD may be a causal gene in progressive neurodegenerative encephalopathy with atypical infantile spinal muscular atrophy.

TBCD BAHCC1

2.08e-052159227928163
Pubmed

Annexins: from structure to function.

ANXA8L1 ANXA8

2.08e-052159211917092
Pubmed

Kv12-encoded K+ channels drive the day-night switch in the repetitive firing rates of SCN neurons.

KCNH8 KCNH3

2.08e-052159237516908
Pubmed

Annexin A8 controls leukocyte recruitment to activated endothelial cells via cell surface delivery of CD63.

ANXA8L1 ANXA8

2.08e-052159224769558
Pubmed

CHD1 and CHD2 are positive regulators of HIV-1 gene expression.

CHD1 CHD2

2.08e-052159225297984
Pubmed

Cloning and partial characterization of the mouse glutamine:fructose-6-phosphate amidotransferase (GFAT) gene promoter.

GFPT1 GFPT2

2.08e-05215929060444
Pubmed

MUC4 expression is regulated by cystic fibrosis transmembrane conductance regulator in pancreatic adenocarcinoma cells via transcriptional and post-translational mechanisms.

CFTR MUC4

2.08e-052159216799633
Pubmed

Mammalian INO80 chromatin remodeler cooperates with FANCM to mediate DNA interstrand crosslink-induced checkpoint activation and repair.

INO80 FANCM

2.08e-052159230606611
Pubmed

Cardiomyocyte protein O-GlcNAcylation is regulated by GFAT1 not GFAT2.

GFPT1 GFPT2

2.08e-052159234735873
Pubmed

Annexins: linking Ca2+ signalling to membrane dynamics.

ANXA8L1 ANXA8

2.08e-052159215928709
Pubmed

An anillin-Ect2 complex stabilizes central spindle microtubules at the cortex during cytokinesis.

ECT2 ANLN

2.08e-052159222514687
Pubmed

A novel spliced fusion of MLL with CT45A2 in a pediatric biphenotypic acute leukemia.

CT45A2 KMT2A

2.08e-052159220920256
Pubmed

Annexin A8 identifies a subpopulation of transiently quiescent c-kit positive luminal progenitor cells of the ductal mammary epithelium.

ANXA8L1 ANXA8

2.08e-052159225803307
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NPC1 UNC13B TMEM59 GRIK1 GFPT1 STAB1 SETDB1 TXNDC15 DDX18 C1S GFPT2 LRBA ZNF606 GNB1 WDR13 HECTD1 BTRC MAPK8IP2

2.59e-0512851591835914814
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

NPC1 HSPG2 CAD LAMB2 MYORG TXNDC15 SUSD1 DDX18 GNB4 ARHGEF2 PLXNA1 KIF11

2.74e-056131591222268729
Pubmed

VHL negatively regulates SARS coronavirus replication by modulating nsp16 ubiquitination and stability.

STAB1 SETDB1 GNB2

3.29e-0514159325732088
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

KCNH8 DNAH10 SHMT2 DGKH GFPT1 GIPC3 KCNH3 DMXL1 KMT2A GFPT2 PLXNA1 WNK3 KIF11

3.37e-057301591334857952
Pubmed

Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta.

GNB4 GNB1 GNB2

4.10e-0515159312486123
Pubmed

Identification of cancer/testis-antigen genes by massively parallel signature sequencing.

CT45A2 CT45A9 CT45A8

4.10e-0515159315905330
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SLAIN2 PDGFRA ECT2 MICALL1 ANLN SH3PXD2A SAMD11 KMT2A ARHGEF2 HECTD1 WNK3 PHLDB2 KIF11 DCAF7

4.48e-058611591436931259
Pubmed

Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.

HSPG2 COL6A2 FREM2

5.03e-0516159316880404
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

NPC1 CT45A2 ARFGEF1 SHMT2 TIPRL GFPT1 SETDB1 PELP1 ANLN DDX18 NUDCD1 WDR1 GNB1 PLRG1 PHLDB2 TBCD KIF11 XPO7

5.76e-0513671591832687490
Pubmed

Role of molecular chaperones in G protein beta5/regulator of G protein signaling dimer assembly and G protein betagamma dimer specificity.

GNB4 GNB1 GNB2

6.08e-0517159319376773
Pubmed

GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway.

GFPT1 GFPT2

6.21e-053159235229715
Pubmed

Specific expression of annexin A8 in adult murine stratified epithelia.

ANXA8L1 ANXA8

6.21e-053159217082908
Pubmed

Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.

GNB1 GNB2

6.21e-053159225485910
Pubmed

MgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesis.

ECT2 ANLN

6.21e-053159216129829
Pubmed

Vascular anticoagulant beta: a novel human Ca2+/phospholipid binding protein that inhibits coagulation and phospholipase A2 activity. Its molecular cloning, expression and comparison with VAC-alpha.

ANXA8L1 ANXA8

6.21e-05315922530088
Pubmed

Pyruvate dehydrogenase activation and kinase expression in human skeletal muscle during fasting.

PDK3 PDK4

6.21e-053159214966024
Pubmed

Deacetylation of serine hydroxymethyl-transferase 2 by SIRT3 promotes colorectal carcinogenesis.

PDGFRA SHMT2

6.21e-053159230367038
Pubmed

CHD1 and SPOP synergistically protect prostate epithelial cells from DNA damage.

CHD1 CHD2

6.21e-053159233022763
Pubmed

Cytokinetic diversity in mammalian cells is revealed by the characterization of endogenous anillin, Ect2 and RhoA.

ECT2 ANLN

6.21e-053159236416720
Pubmed

Human RNA polymerase II-association factor 1 (hPaf1/PD2) regulates histone methylation and chromatin remodeling in pancreatic cancer.

CHD1 KMT2A

6.21e-053159222046413
Pubmed

Distribution and functional properties of human KCNH8 (Elk1) potassium channels.

KCNH8 KCNH3

6.21e-053159212890647
Pubmed

Selective association of G protein beta(4) with gamma(5) and gamma(12) subunits in bovine tissues.

GNB4 GNB2

6.21e-053159210409705
Pubmed

Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer.

CHD1 BTRC

6.21e-053159228166537
Pubmed

Genomic organization of the murine G protein beta subunit genes and related processed pseudogenes.

GNB1 GNB2

6.21e-053159211913780
Pubmed

Recurrent YAP1 and KMT2A Gene Rearrangements in a Subset of MUC4-negative Sclerosing Epithelioid Fibrosarcoma.

KMT2A MUC4

6.21e-053159231592798
Pubmed

Taking the next step forward - Diagnosing inherited infantile cholestatic disorders with next generation sequencing.

NPC1 PKHD1

6.21e-053159225771912
Pubmed

G protein beta gamma subunits. Simplified purification and properties of novel isoforms.

GNB1 GNB2

6.21e-05315928308009
Pubmed

Adhesion G protein-coupled receptor G2 is dispensable for lumicrine signaling regulating epididymal initial segment differentiation and gene expression†.

ADGRG2 ROS1

6.21e-053159237531264
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

ELOB CAD SHMT2 OSGEP ECT2 GFPT1 RIF1 KLHL21 GNB4 ELP2 GNB1 GNB2 OGA HECTD1 PLRG1 TBCD DCAF7

6.77e-0512571591737317656
Pubmed

Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities.

GRIK1 AK9 TENM4

7.27e-0518159320602751
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

SLAIN2 ELOB SHMT2 CHD1 ECT2 PLEKHG4B RIF1 SH3PXD2A KMT2A WDR1 ARHGEF2 PLRG1 BTRC DCAF7

8.65e-059161591432203420
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UNC13B RIPOR2 ZSWIM6 SETDB1 KIRREL3 KIDINS220 TENM4 MAPKBP1 XPO7

1.15e-04407159912693553
Pubmed

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.

HSPG2 PDGFRA FREM2

1.17e-0421159327856617
Pubmed

Tissue-specific kinase expression and activity regulate flux through the pyruvate dehydrogenase complex.

PDK3 PDK4

1.24e-044159230482839
Pubmed

Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta.

PDK3 PDK4

1.24e-044159217669420
Pubmed

Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis.

FANCM BTRC

1.24e-044159219270156
Pubmed

Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation.

PDK3 PDK4

1.24e-044159225991547
Pubmed

Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.

CFTR ADGRG2

1.24e-044159229393851
Pubmed

Rho and anillin-dependent control of mDia2 localization and function in cytokinesis.

ECT2 ANLN

1.24e-044159220660154
Pubmed

Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice.

CFTR ITPR1

1.24e-044159223542070
Pubmed

Diversity of the pyruvate dehydrogenase kinase gene family in humans.

PDK3 PDK4

1.24e-04415927499431
Pubmed

Segmental and restricted localization pattern of Fras1 in the developing meningeal basement membrane in mouse.

LAMB2 FREM2

1.24e-044159224101214
Pubmed

Characterization of the CHD family of proteins.

CHD1 CHD2

1.24e-04415929326634
Pubmed

Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish.

GFPT1 GFPT2

1.24e-044159217542649
Pubmed

ECSASB2 mediates MLL degradation during hematopoietic differentiation.

ELOB KMT2A

1.24e-044159222174154
Pubmed

G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus.

GNB1 GNB2

1.24e-044159215955845
Pubmed

NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression.

SETDB1 PELP1

1.24e-044159216567619
Pubmed

The cationic region of Rhes mediates its interactions with specific Gbeta subunits.

GNB1 GNB2

1.24e-044159219255495
Pubmed

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.

ANAPC16 ELP2 LRBA DCAF7 XPO7

1.31e-04106159531024071
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

NPC1 HSPG2 TMEM59 ARFGEF1 LAMB2 MYORG DMXL1 ITPR1 TSKU TXNDC15 SELENOF HECTD1 ZDHHC13 PLXNA1 SLC27A3 CD276

1.33e-0412011591635696571
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

HSPG2 COL6A2 LAMB2 COL6A5 SSPOP MUC4

1.61e-04175159628071719
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

CAD SHMT2 CHD1 CHD2 ECT2 GFPT1 RIF1 ANLN DDX18 WDR1 ARHGEF2 GNB2 WDR13 PLRG1 BTRC PHLDB2 KIF11

1.64e-0413531591729467282
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

SHMT2 LAMB2 CHD1 OSGEP TIPRL GFPT1 MYORG KIDINS220 WDR1 HECTD1 BTRC KIF11 SLC27A3 DCAF7

1.64e-049741591428675297
Pubmed

KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression.

GNB4 GNB1 GNB2

1.77e-0424159323209302
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

CAD GFPT1 ITPR1 SETDB1 PELP1 DDX18 GFPT2 ARHGEF2 HECTD1

2.05e-04440159934244565
Pubmed

Gbeta gamma isoforms selectively rescue plasma membrane localization and palmitoylation of mutant Galphas and Galphaq.

GNB4 GNB1

2.06e-045159211294873
GeneFamilyWD repeat domain containing

DMXL1 GNB4 ELP2 LRBA WDR1 MAPKBP1 GNB1 GNB2 WDR13 PLRG1 BTRC DCAF7

3.94e-0826210512362
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS15 COL19A1 DNAH10 CFTR SSPOP FREM2 TENM4 PKHD1 ROS1

2.09e-0818415892cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS15 COL19A1 DNAH10 CFTR SSPOP FREM2 TENM4 PKHD1 ROS1

2.09e-081841589ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS15 COL19A1 DNAH10 CFTR SSPOP FREM2 TENM4 PKHD1 ROS1

2.09e-0818415892b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldistal-mesenchymal-Adventitial_Fibroblast-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A2 HTR2A PDGFRA GRIK1 TSKU LMX1A SAMD11 C1S GFPT2

4.11e-0819915896e8a44e46b46e87b81dbfc56fcbbcde166fd00fe
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ARFGEF1 CHD1 DGKH CHD2 ITPR1 KMT2A NOCT LRBA

3.77e-071881588ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDGFRA CENPL ECT2 HOXB2 TENM4 ANLN NEIL3 KIF11

3.77e-07188158895d0a796d62ce6d121e2028c378faffc14b35275
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B MACC1 KCNH8 RFX6 ECT2 FREM2 PKHD1 NEIL3

4.43e-07192158825378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDGFRA CENPL ECT2 HOXB2 TENM4 ANLN NEIL3 KIF11

4.61e-071931588a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

UNC13B MACC1 KCNH8 ST14 PLEKHG4B FREM2 PKHD1 ROS1

4.79e-071941588c011cd59bb4ca4134331cba0f5d73bdbd7011d64
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B LANCL3 MACC1 KCNH8 CFTR ST14 FREM2 PKHD1

4.79e-071941588f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCellPCW_10-12-Epithelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

UNC13B LANCL3 MACC1 KCNH8 ST14 FREM2 PKHD1 CATSPERB

5.18e-0719615889bfb31ff3e4f2c0a9405c418c86bfec5dbca23e2
ToppCelldistal-3-mesenchymal-Adventitial_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A2 HTR2A PDGFRA TSKU LMX1A SAMD11 C1S GFPT2

5.81e-071991588547a7c30abc730af2670aee00c7a6af60426c9ac
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHFPL4 DNAH10 PAPOLB ECT2 TENM4 ANLN PLXNA1

1.94e-0616315878dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHFPL4 DNAH10 PAPOLB ECT2 TENM4 ANLN PLXNA1

1.94e-061631587fd243ca223079033be480a24817a399f281fa4d4
ToppCellBasal_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

GRK4 PERM1 ANXA8 DGKH ATP8B1 PLEKHG4B RAPGEFL1

2.56e-061701587776d4224a682b6c648041827efd69794f88906f0
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACC1 DGKH CHD2 SH3PXD2A CATSPERB MUC4 RAPGEFL1

3.61e-0617915876e965e424eebef50f0202cff75f458be395cfca1
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

UNC13B LANCL3 MACC1 KCNH8 FREM2 PKHD1 ROS1

4.64e-061861587bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

UNC13B LANCL3 MACC1 KCNH8 CFTR FREM2 PKHD1

4.98e-0618815870d86044bc340e3efb90d0022dd299873639d831c
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

UNC13B LANCL3 MACC1 KCNH8 CFTR FREM2 PKHD1

4.98e-061881587beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCellCOPD-Epithelial-Mesothelial|Epithelial / Disease state, Lineage and Cell class

COL6A2 ANXA8L1 ANXA8 PPARGC1B C1S GFPT2 PHLDB2

4.98e-061881587159d63ecc3653a7449fc6acefd6ef0464845260e
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MACC1 KCNH8 RFX6 ECT2 ST14 FREM2 PKHD1

5.16e-061891587c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UNC13B CFTR FREM2 PKHD1 ROS1 LRBA ARHGEF2

5.34e-0619015878aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B MACC1 RFX6 ST14 PLEKHG4B FREM2 PKHD1

5.34e-061901587625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LANCL3 MACC1 KCNH8 CFTR ATP8B1 FREM2 PKHD1

5.53e-06191158760ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

UNC13B ECT2 FREM2 ANLN PKHD1 NEIL3 KIF11

5.53e-06191158739220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UNC13B MACC1 CFTR FREM2 PKHD1 ROS1 ARHGEF2

5.53e-061911587ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PDGFRA CENPL ECT2 HOXB2 ANLN NEIL3 KIF11

5.72e-0619215875ef79faddb433c09ff36660d8bf7a3af5a67bf1d
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B MACC1 KCNH8 RFX6 ST14 FREM2 PKHD1

5.72e-061921587d3634574b2e8d2ded6446969361b70761b331aea
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B MACC1 KCNH8 RFX6 ST14 FREM2 PKHD1

5.72e-0619215871aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

UNC13B MACC1 KCNH8 ST14 FREM2 PKHD1 CATSPERB

6.12e-061941587c5ef4ff73b4e51530656002e3a2fb7264cdf533d
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

UNC13B MACC1 ECT2 FREM2 ANLN PKHD1 NEIL3

6.12e-061941587c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

UNC13B MACC1 KCNH8 RFX6 ST14 FREM2 PKHD1

6.12e-061941587acd5ba9a097595d4caab4f05440531c65a4aa7bc
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

COL6A2 PCNX2 KIRREL3 TENM4 LMX1A C1S GFPT2

6.12e-061941587d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B MACC1 KCNH8 RFX6 ST14 FREM2 PKHD1

6.12e-061941587f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

UNC13B LANCL3 MACC1 ST14 FREM2 PKHD1 ROS1

6.12e-061941587c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RFX6 ATP8B1 GFPT1 IGFALS SH3PXD2A MUC4 MAPK8IP2

6.33e-061951587bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

UNC13B LANCL3 MACC1 ST14 FREM2 PKHD1 ROS1

6.33e-06195158798dd3b7d5ef587825dac052dea4d4ff883f6d4d6
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFRA CENPL ECT2 ANLN NEIL3 KIF11 DCAF7

6.33e-061951587742c82c86487314cdb3178012004adb1164bcbdb
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

UNC13B MACC1 ST14 FREM2 PKHD1 CATSPERB ROS1

6.55e-0619615877b17d47b7758d8ccf9dbefd097aeb553791a1eed
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

UNC13B COL6A2 LAMB2 FREM2 C1S GFPT2 PLXNA1

6.55e-061961587b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A2 PDGFRA CENPL ECT2 HOXB2 ANLN KIF11

6.77e-06197158729b0a5927f80455eef7b793feabef69fba1a3df1
ToppCellPCW_10-12-Epithelial-Epithelial_airway|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LANCL3 MACC1 KCNH8 CFTR FREM2 PKHD1 CATSPERB

6.99e-0619815879a12e5e47236433e512c668005fe3f8be6fde95c
ToppCellTransverse-T_cell-Tfh|Transverse / Region, Cell class and subclass

DGKH ECT2 THAP9 ZNF563 SH3TC1 WDR1 PLXNA1

7.23e-061991587cbef8f95edf2e86e16c448a76068d7ed8f6b7748
ToppCellTransverse-(1)_T_cell-(16)_Tfh|Transverse / shred on region, Cell_type, and subtype

DGKH ECT2 THAP9 ZNF563 SH3TC1 WDR1 PLXNA1

7.23e-061991587aa31e26d48066f865ca33251a33a28934c0a7a44
ToppCellTransverse-T_cell-Tfh|T_cell / Region, Cell class and subclass

DGKH ECT2 THAP9 ZNF563 SH3TC1 WDR1 PLXNA1

7.23e-06199158733ffea12b8228e0b5bd8942531c3b21d24224725
ToppCellTCGA-Stomach-Primary_Tumor|TCGA-Stomach / Sample_Type by Project: Shred V9

CAD CENPL ECT2 ANLN DDX18 NUDCD1 KIF11

7.23e-06199158738f1f612b29feb868322999ceeda78e52447ec4f
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma|TCGA-Stomach / Sample_Type by Project: Shred V9

CAD CENPL ECT2 ANLN DDX18 NUDCD1 KIF11

7.23e-061991587b10698aee2e6c17bc559eb4f723024141f914b90
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 COL19A1 POM121L2 COL6A5 STAB1 MUC4

1.93e-0515515868fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LHFPL4 DNAH10 PAPOLB ECT2 TENM4 PLXNA1

2.08e-051571586ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Hippocampus / BrainAtlas - Mouse McCarroll V32

LANCL3 HTR2A COL19A1 GRIK1 GFPT1 GFPT2

2.40e-051611586b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RIPOR2 KCNH8 COL19A1 ITPR1 SELENOF OGA

2.75e-051651586fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPL SARM1 FANCM NEIL3 NOCT KIF11

3.47e-051721586ba36581ae339191a12a6d3ead39eaf69d78be10e
ToppCellmetastatic_Brain-B_lymphocytes-MALT_B_cells|metastatic_Brain / Location, Cell class and cell subclass

MYF6 IGHV3-43 IGHV3-20 ICAM3 MEI1 TXNDC15

3.95e-05176158650e207403d48ce1b55a78897adb5519a2430a626
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYF6 ANXA8 KCNH3 FREM2 NEIL3 GFPT2

3.95e-0517615868e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYF6 ANXA8 KCNH3 FREM2 NEIL3 GFPT2

3.95e-051761586ed575330a08a6748ea4b28433292c8cfd157d444
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UNC13B MACC1 CFTR FREM2 ROS1 LRBA

4.34e-051791586815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell390C-Lymphocytic-ILC-ILC-1|390C / Donor, Lineage, Cell class and subclass (all cells)

ZNF678 AMDHD1 MEI1 KCTD11 ZNF16 IFNL1

4.34e-051791586e7045e27f0eb88f552b31c04b56d78e5ccd7a36c
ToppCell(05)_Ciliated-(4)_1wkpi|(05)_Ciliated / shred by cell type and Timepoint

DNAH10 AK9 ST14 NUDCD1 NOCT MAPKBP1

4.48e-05180158685fc9b164147b28545e2397d32302eea03ef6346
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CENPL DGKH ECT2 ANLN NEIL3 KIF11

4.48e-051801586334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 MACC1 ECT2 C1S GFPT2 KIF11

4.62e-051811586c26d3cbbc592299786d79d1b15fc6bead2aafb9a
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 ECT2 NEIL3 MAPKBP1 PLXNA1 KIF11

4.62e-0518115863fe648db1cb8326066d8bde3ca1287c5c9af19bd
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass

MACC1 RIPOR2 KCNH3 CCNG2 CATSPERB LRBA

4.62e-051811586cc7ae1221a28bc404138a7efee0ad08a19cc3d86
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

UNC13B MACC1 CFTR FREM2 ROS1 MUC4

4.62e-051811586c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPL ECT2 ST14 SUSD1 NEIL3 KIF11

4.76e-0518215863948422707d6d5e021bcd7158e2eb69143613f62
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPL ECT2 ST14 SUSD1 NEIL3 KIF11

4.76e-051821586fe46819c153a81911864473badc794f243705f98
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

UNC13B MACC1 KCNH8 ST14 FREM2 PKHD1

4.91e-051831586c5b10571599dc26476170b54b53f09c23e6b3117
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A2 PDGFRA ADGRG2 SAMD11 C1S GFPT2

4.91e-05183158606a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCellIPF-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

COL6A2 ANXA8L1 ANXA8 C1S GFPT2 PHLDB2

4.91e-0518315867df20e3172a1220ff427f30181f4f0c3b7fe2d42
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 MACC1 PLEKHG4B SLC12A9 PKHD1 PHLDB2

5.06e-05184158642ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellCOPD-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

COL6A2 ANXA8L1 ANXA8 C1S GFPT2 PHLDB2

5.21e-05185158623579988036fc1925992c31919750f9b3fe9f790
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

UNC13B CFTR ACSS2 PLEKHG4B ROS1 MUC4

5.21e-051851586cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UNC13B MACC1 CFTR FREM2 ROS1 LRBA

5.37e-0518615862ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 PDGFRA LAMB2 TSKU C1S GFPT2

5.37e-051861586a7ab70b049742dfe7ee30557031bfac6412edf52
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A2 TSKU ADGRG2 LMX1A C1S GFPT2

5.37e-05186158607d94d5d1c2fe7bb909a07ca81058a0eabc65c60
ToppCelldroplet-Marrow-nan-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPST CENPL ECT2 SAMD11 NEIL3 KIF11

5.53e-05187158699724aa3dbdcb073ea3bfe80cc825ecae5495db8
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UNC13B CFTR FREM2 PKHD1 ROS1 ARHGEF2

5.53e-0518715865df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDGFRA PAPOLB ATP8B1 ADGRG2 C1S GFPT2

5.70e-051881586aa516273cdde53c8c0295f06830972388f890c97
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NPC1 HSPG2 MACC1 ST14 CATSPERB MUC4

5.70e-05188158643a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ELOB PDGFRA AK9 DDX18 BTN2A3P CATSPERB

5.70e-0518815860476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

UNC13B LANCL3 MACC1 KCNH8 FREM2 PKHD1

5.70e-0518815863cfba3addcc9058f4ec31ad96261f79988f551a0
ToppCellCOPD-Epithelial-Mesothelial|COPD / Disease state, Lineage and Cell class

COL6A2 ANXA8L1 ANXA8 C1S GFPT2 PHLDB2

5.87e-05189158679bb2593ad5d17f94b17972884241f03a0f43770
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

CHD1 SYAP1 SH3PXD2A CATSPERB GFPT2 PHLDB2

5.87e-0518915863922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B KCNH8 RFX6 ST14 FREM2 PKHD1

5.87e-0518915865d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

COL6A2 CHD1 SH3PXD2A CATSPERB GFPT2 PHLDB2

5.87e-05189158646e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

COL6A2 PDGFRA PAPOLB C1S GFPT2 PHLDB2

5.87e-05189158687189275234b5d59484c58acbb14a09903f2b578
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B MACC1 KCNH8 CFTR FREM2 PKHD1

5.87e-0518915867659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ECT2 ANLN NEIL3 GNB4 KIF11

6.04e-05190158631de1727822e9818652946dfb962daee77ffad68
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B MACC1 KCNH8 ST14 FREM2 PKHD1

6.04e-051901586c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 PDGFRA LAMB2 ANXA8 C1S GFPT2

6.04e-051901586d13fd234caa3fc69d8a59bc0060cdacdf716ee55
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PDK4 ITPR1 STAB1 SH3PXD2A MAPKBP1 BAHCC1

6.04e-05190158663018acb7ad80415e861643162abdc2e55968ee4
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPST CENPL SAMD11 NEIL3 NOCT KIF11

6.04e-0519015864288189e3a499c395896c950598810b02f401685
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 PDK4 ZSWIM6 SUSD1 PKHD1 LRBA

6.22e-0519115863e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A2 PDGFRA PDK4 C1S GFPT2 PHLDB2

6.22e-051911586f5ce33af56178333730be308253943c54a0724cf
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

UNC13B MACC1 KCNH8 ST14 FREM2 PKHD1

6.22e-05191158605731ece7867659c662f952812805f947032fe10
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

NPC1 UNC13B CFTR ACSS2 FREM2 ROS1

6.22e-051911586a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 PDGFRA ATP8B1 ITPR1 C1S GFPT2

6.22e-051911586b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

UNC13B LANCL3 MACC1 KCNH8 FREM2 PKHD1

6.22e-05191158663aa671837b79d2feb7ed1e67712cc01caf72bef
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

UNC13B MACC1 CFTR FREM2 PKHD1 ARHGEF2

6.22e-051911586d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PDGFRA CENPL ECT2 ANLN NEIL3 KIF11

6.22e-051911586b978afe76754cc56e1672abca27be289bb56375b
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CENPL ECT2 HOXB2 ANLN NEIL3 KIF11

6.22e-051911586f764cc21fef87ebad765011098f647ae1bdf6158
DrugAvl-FMDP

ICAM3 GFPT1 GFPT2

2.86e-0731513CID006473933
DrugAC1O5Y0I

ICAM3 GFPT1 GFPT2

1.14e-0641513CID006442853
DrugProparacaine hydrochloride [5875-06-9]; Down 200; 12uM; MCF7; HT_HG-U133A

CEP104 PDK3 PDK4 SETDB1 KIDINS220 GFPT2 NOCT MAPK8IP2 BAHCC1

7.52e-0619915196492_DN
DiseaseParoxysmal atrial fibrillation

HSPG2 DNAH10 SH3PXD2A GNB4 WDR1 PHLDB2 XPO7

1.44e-051561487C0235480
Diseasefamilial atrial fibrillation

HSPG2 DNAH10 SH3PXD2A GNB4 WDR1 PHLDB2 XPO7

1.44e-051561487C3468561
DiseasePersistent atrial fibrillation

HSPG2 DNAH10 SH3PXD2A GNB4 WDR1 PHLDB2 XPO7

1.44e-051561487C2585653
DiseaseAtrial Fibrillation

HSPG2 DNAH10 SH3PXD2A GNB4 WDR1 PHLDB2 XPO7

1.70e-051601487C0004238
Diseaseatrial fibrillation

HSPG2 DNAH10 PERM1 MEI1 LMX1A SH3PXD2A GNB4 WDR1 PHLDB2 XPO7

1.92e-0537114810EFO_0000275
DiseaseCongenital bilateral aplasia of vas deferens

CFTR ADGRG2

2.50e-0521482C0403814
Diseaseglucose-dependent insulinotropic peptide measurement

RIPOR2 GRIK1 SETDB1 TBCD

1.47e-04531484EFO_0008464
DiseaseMachado-Joseph disease (implicated_via_orthology)

GFPT1 GFPT2

1.49e-0441482DOID:1440 (implicated_via_orthology)
DiseaseS-formylglutathione hydrolase measurement

HTR2A SARM1

2.47e-0451482EFO_0008275
DiseaseCholedochal Cyst, Type I

CFTR PKHD1

2.47e-0451482C0009439
DiseaseCholedochal Cyst, Type II

CFTR PKHD1

2.47e-0451482C1257796
DiseaseCholedochal Cyst, Type III

CFTR PKHD1

2.47e-0451482C1257797
DiseaseCholedochal Cyst, Type IV

CFTR PKHD1

2.47e-0451482C1257798
DiseaseCholedochal Cyst, Type V

CFTR PKHD1

2.47e-0451482C1257799
DiseaseCholedochal Cyst

CFTR PKHD1

2.47e-0451482C0008340
Diseaseclusterin measurement

SARM1 C1S

5.16e-0471482EFO_0007655
DiseaseDyskinetic syndrome

HTR2A MYORG

5.16e-0471482C0013384
DiseaseAutosomal Recessive Polycystic Kidney Disease

CFTR PKHD1

8.79e-0491482C0085548
Diseaseautism spectrum disorder (implicated_via_orthology)

HTR2A CHD1 CHD2 ELP2 LRBA

1.04e-031521485DOID:0060041 (implicated_via_orthology)
DiseaseProstatic Neoplasms

LAMB2 CHD1 RFX6 ST14 ITPR1 SETDB1 KMT2A ZNF160 MUC4 CD276

1.14e-0361614810C0033578
DiseaseMalignant neoplasm of prostate

LAMB2 CHD1 RFX6 ST14 ITPR1 SETDB1 KMT2A ZNF160 MUC4 CD276

1.14e-0361614810C0376358
Diseaseautosomal recessive polycystic kidney disease (biomarker_via_orthology)

CFTR PKHD1

1.33e-03111482DOID:0110861 (biomarker_via_orthology)
Diseasecannabis dependence measurement

MEI1 DDX18 PKHD1

1.81e-03481483EFO_0008457
Diseaseneuroticism measurement

UNC13B COL19A1 POM121L2 GRIK1 KCNH3 ITPR1 STAB1 KIRREL3 PKHD1 KMT2A NOCT WDR1

2.16e-0390914812EFO_0007660
Diseaseserum gamma-glutamyl transferase measurement

PERM1 ATP8B1 ITPR1 STAB1 TENM4 PKHD1 KMT2A C1S LRBA ARHGEF2 CD276 BAHCC1

2.26e-0391414812EFO_0004532
Diseaseidiopathic scoliosis (implicated_via_orthology)

DNAH10 SSPOP

2.86e-03161482DOID:0060250 (implicated_via_orthology)
DiseaseCongenital Myasthenic Syndromes, Postsynaptic

AK9 GFPT1

3.23e-03171482C0751883
Diseaseparahippocampal gyrus volume measurement

FREM2 NOCT

3.63e-03181482EFO_0010318
DiseaseLiver carcinoma

PDK4 ECT2 IGFALS ANLN KMT2A NEIL3 KIF11 CD276

4.18e-035071488C2239176
Diseasewhite matter hyperintensity measurement

ZSWIM6 ZNF16 PPARGC1B SH3PXD2A KLHL21 CATSPERB

4.29e-033021486EFO_0005665
Diseaseresponse to ziprasidone

TENM4 NOCT

4.47e-03201482GO_0097337
DiseasePrecursor B-cell lymphoblastic leukemia

PDGFRA KMT2A

4.93e-03211482C1292769
Diseaselung cancer

GRIK1 ATP8B1

4.93e-03211482MONDO_0008903

Protein segments in the cluster

PeptideGeneStartEntry
RFDSQLCVLGQESFA

BTN2A3P

336

Q96KV6
DDFLEDFLCFLNLTS

FAM200B

251

P0CF97
RAFACREEGSQLASE

BAHCC1

1781

Q9P281
LEDGSERFLCESVFS

ANAPC16

46

Q96DE5
GCDSFDQFSAERRNS

CFTR

646

P13569
LSFSRADFCGFERVD

CATSPERB

276

Q9H7T0
FLAAFSVGLQDCDDT

ARFGEF1

956

Q9Y6D6
RTFNGSIELCRADSD

ARHGEF2

706

Q92974
LFDSFEASRRACDQL

GRIK1

86

P39086
GALTAFQNSSEREDC

BTRC

46

Q9Y297
SCLLADDNFVLIGSF

HTR2A

226

P28223
NLSSICNDSAFFRGE

ADGRG2

111

Q8IZP9
EDLRSLANFFGSCTE

CCNG2

61

Q16589
FSGECSNLADRGFDR

CRYBB1

76

P53674
DDADELSVFCSSRNL

IGFALS

51

P35858
AQEFARCLDSVLGEF

GIPC3

276

Q8TF64
DEGSFTCFVSIRDFG

CD276

116

Q5ZPR3
FAGFSSESLCERILD

ACSS2

191

Q9NR19
CVDDFTARALGADFL

DPH1

116

Q9BZG8
NAEGSEDFCFLLSTR

CHD1

851

O14646
FCSDAEELQSAFGRN

DMXL1

2076

Q9Y485
GLDEESSEFICRNTF

DCAF7

51

P61962
QREDTLATFDGFIEC

ATP8B1

251

O43520
ASRRFSDTCFLDTDG

HSPG2

821

P98160
TEQQLSRDFFSGSCA

RFX6

731

Q8HWS3
SEAGQCRFSREEFEQ

RILP

236

Q96NA2
FQDCILSFLGFSDEE

ECT2

271

Q9H8V3
SENFCSRAALEALGS

SHMT2

76

P34897
GINEESCFSFLRFID

INO80

881

Q9ULG1
DIFFEESSSLCRFDG

NUDCD1

411

Q96RS6
SDGFCDLTGFSRAEV

KCNH3

46

Q9ULD8
LDFGSENACERTSFA

PDK4

41

Q16654
CLLQGSRDDVSSFVD

ANXA8

161

P13928
LTDLNDSSFDLSAGC

PAPOLB

516

Q9NRJ5
LNSSFSLRCFGESEV

PDGFRA

41

P16234
ANFTLRDSCTDLELF

MUC4

4981

Q99102
LSDACEREFGFLATR

KIDINS220

621

Q9ULH0
SLRLSCAASGFTFDD

IGHV3-43D

36

P0DP04
SRFRETFQEALCLGA

NMUR1

361

Q9HB89
DLICFFDSSVELRNS

NEIL3

126

Q8TAT5
FLCLEDARGSSFGVF

MGAM2

261

Q2M2H8
TGESLASEFLFSDVC

ITPR1

2491

Q14643
ASEFLFSDVCRVESG

ITPR1

2496

Q14643
FLSTLNFSGEDLRCV

NLRP11

406

P59045
NFSGEDLRCVGFTEA

NLRP11

411

P59045
KFCADSDGFSQELRN

KIF11

771

P52732
EATFCSQRDGDASLN

ANLN

256

Q9NQW6
SLRLSCAASGFTFDD

IGHV3-9

36

P01782
GSDEADCVRFFNGTT

TMPRSS15

671

P98073
FDCSRDLFSVTFDLG

FANCM

1221

Q8IYD8
DRFVFRCSDGINFSE

FREM2

1161

Q5SZK8
ESFGLFSCLVNGEER

MAPK8IP2

591

Q13387
AATQCEFSRKEFLDG

DCUN1D2

111

Q6PH85
GDCFILASDDLNAFV

PCNX2

1416

A6NKB5
SESGIFACAFDQSES

PLRG1

461

O43660
DLSAGVNCSFEDFTE

PLXNA1

591

Q9UIW2
DDTSLSNLGDCFLAT

LMX1A

341

Q8TE12
QENLEGADFLRTCSS

MYF6

171

P23409
SFLECGSDELFVGRA

LANCL3

161

Q6ZV70
DKCFLGSSETADANR

LRBA

341

P50851
QCRDGFFGLSISDRL

LAMB2

451

P55268
DLSSSFRDGLAFCAI

MICALL1

26

Q8N3F8
FTTGSDDATCRLFDL

GNB2

241

P62879
FATGSDDATCRLFDL

GNB4

241

Q9HAV0
CTLGEAFNRLDFSSA

FBXO25

101

Q8TCJ0
SLRLSCAASGFTFDD

IGHV3-20

36

A0A0C4DH32
TGAFEDTSFASLCNL

DDX18

171

Q9NVP1
IALNSTDSDGFCRAT

DGKH

311

Q86XP1
GARLFATDERFCIDN

OSGEP

281

Q9NPF4
SLGQREDSLEVSSFC

PELP1

606

Q8IZL8
AGRELTCRGSFTDFS

LHFPL4

71

Q7Z7J7
SLRLSCAASGFTFDD

IGHV3-43

36

A0A0B4J1X8
QLNATESDDGRSFFC

ICAM3

361

P32942
ESDDGRSFFCSATLE

ICAM3

366

P32942
EGFRSACRLAIEFQS

MEI1

506

Q5TIA1
DLNFFAADSCLQLSG

HOXB2

306

P14652
DGTSVQASESCLFRF

NPC1

806

O15118
DNLCIFCGERSESFT

CEP104

751

O60308
SFSGDDLECRETAFS

CT45A9

101

P0DMV2
QVSDGALRCFASLAD

HECTD1

201

Q9ULT8
EAFSCSGLASAAQRF

KLHL21

146

Q9UJP4
CLLQGSRDDVSSFVD

ANXA8L1

161

Q5VT79
DVCFFISQSGETADT

GFPT2

416

O94808
FGDSLLETVSEDFTC

CENPL

166

Q8N0S6
CLDFTSSRSGDLEAA

DTX3L

276

Q8TDB6
FATGSDDATCRLFDL

GNB1

241

P62873
GLAFRADDTFEALCI

ELOB

76

Q15370
DGSEDFCFLLSTRAG

CHD2

856

O14647
GFDLGDSFSLRRAFC

COL19A1

56

Q14993
VIFLCDGSDRVSNSD

COL6A5

1006

A8TX70
SFSGDDLECRETAFS

CT45A2

101

Q5DJT8
SSFRRGTFTDCALAN

COL6A2

126

P12110
SAGCLEASVTFNLFR

IFNL1

161

Q8IU54
EAADSAGNCLDSLVF

C1S

226

P09871
FLFCREIENGNSFDS

MACC1

101

Q6ZN28
RQFSGETFEEIIDCS

AMDHD1

61

Q96NU7
SDKNLSIFDFSSGEC

MAPKBP1

681

O60336
SFSGDDLECRETAFS

CT45A8

101

P0DMV1
LCEREFQRGSLSDSS

KIRREL3

706

Q8IZU9
FEISSDDGFQICAES

KMT2A

3671

Q03164
AAFGRDLFLASCSQD

ELP2

216

Q6IA86
EDRSDCGLSILDRFF

GRK4

96

P32298
GCFDEFNRIDASVLS

DNAH10

1881

Q8IVF4
AEFSATADECGLLQA

PERM1

16

Q5SV97
SLVCDFSFTEESDGL

NOCT

416

Q9UK39
TFRANLFCTDSECLG

KCTD11

121

Q693B1
QELFDCSATDSLEFA

AK9

1651

Q5TCS8
CSATDSLEFAAEFRG

AK9

1656

Q5TCS8
GAAFFDIDQCSDRTS

MPST

56

P25325
CNSTRRGTFSDQELD

SLAIN2

306

Q9P270
LCGDFDGDASNDLRS

SSPOP

1146

A2VEC9
SLENLAAETCFFSGA

SPATA5L1

676

Q9BVQ7
AAETCFFSGADLRNL

SPATA5L1

681

Q9BVQ7
FFSGADLRNLCTEAA

SPATA5L1

686

Q9BVQ7
RDDVCFFLSQSGETA

GFPT1

431

Q06210
VSQFGCRSFALLFDD

OGA

161

O60502
CGVSDERFFLSLESL

RIF1

596

Q5UIP0
GRNFLVTDFATCDEL

PNPLA5

126

Q7Z6Z6
CGALLDEELSSFFLN

PPARGC1B

6

Q86YN6
QLDASDFDSATCFGE

PPARGC1B

46

Q86YN6
FSEGCFSEEDARQLL

SH3TC1

386

Q8TE82
DVNISFREASCSQDG

SAMD11

91

Q96NU1
FNCDESLLASSDASG

WDR13

461

Q9H1Z4
RLATGSDDNCAAFFE

WDR1

161

O75083
SCRDFGIDVLESDAN

PKHD1

2421

P08F94
GVSEFVSDAFDACNL

SYAP1

271

Q96A49
RNFSCGSVEFDEADL

PHLDB2

381

Q86SQ0
QFLDFGRDNACEKTS

PDK3

31

Q15120
TCDTFLLGTAQAFRA

POM121L2

661

Q96KW2
CRSFLDGSLEDAFNG

RIPOR2

596

Q9Y4F9
LFDDASRAVTNCESL

SETDB1

81

Q15047
RDESTLFVCGSNAFN

SEMA6B

136

Q9H3T3
FLEDGESDGFLRCLS

TMEM59

221

Q9BXS4
EECGSAFRAFSTLTE

ZNF273

461

Q14593
CEECGRTFTQFSNLT

ZNF678

351

Q5SXM1
NDCGRAFSDRSSLTF

ZNF160

596

Q9HCG1
LAETGSLDFRTFCTS

ZDHHC13

416

Q8IUH4
GRFARCLVDASDTSQ

SARM1

306

Q6SZW1
SEETECLLRAQFSDF

THAP9

181

Q9H5L6
TGDLLVCDDQGFLRF

SLC27A3

526

Q5K4L6
SGFGIEFNATDALRC

TIPRL

61

O75663
FVDSCQLTADLDGSF

PLEKHG4B

321

Q96PX9
IAEFQSCISDGISFR

SH3PXD2A

456

Q5TCZ1
AFGAEFSSEACRELG

SELENOF

31

O60613
FSSEACRELGFSSNL

SELENOF

36

O60613
EDDGSFNISIFNETC

SUSD1

396

Q6UWL2
SFTCDRTLLQEDYGF

SLC12A9

321

Q9BXP2
LSLTFRSFDLASCDE

ST14

256

Q9Y5Y6
DSRCNVRESLFSLDG

TXNDC15

121

Q96J42
QEAEEFCRTGANFTL

TENM4

66

Q6N022
TEAFSRFETILENCG

STAB1

516

Q9NY15
DALSFNEFIVGCDLS

ROS1

521

P08922
DFLDGNLTLFATVCE

UNC13B

1271

O14795
IGSALFDCRLFEDTF

PHF11

261

Q9UIL8
GARCDFALFLGASSE

CAD

1526

P27708
FASCAFGTEDIRTSG

ZMYND12

201

Q9H0C1
QSFGLAFLRVCSSLD

XNDC1N

141

Q6ZNB5
DSSQCGETFSLIRDS

ZNF563

76

Q8TA94
ACRIDDENLSGFSDF

ZSWIM6

646

Q9HCJ5
CLNFDFIGTSTDESS

XPO7

226

Q9UIA9
KDLDCNGFDSRFSLS

ZNF16

151

P17020
ADDVVGSVLDCFSFQ

TBCD

396

Q9BTW9
DSCLQTRVAFRGSDE

RAPGEFL1

301

Q9UHV5
FGLFDSFSLTRVDCS

TSKU

31

Q8WUA8
SQRSSEFCGLGAEFS

ZNF606

206

Q8WXB4
GDNFLSFSAACETDV

WNK3

1416

Q9BYP7
SDGFCELAGFARTEV

KCNH8

46

Q96L42
FRLAFRSGALDLDSC

MYORG

111

Q6NSJ0