Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpyrimidine nucleotide-sugar transmembrane transporter activity

SLC35D2 SLC35D1 SLC35D3

3.90e-05111263GO:0015165
GeneOntologyMolecularFunctionUDP-glucuronic acid transmembrane transporter activity

SLC35D2 SLC35D1

3.95e-0521262GO:0005461
GeneOntologyMolecularFunctionUDP-N-acetylgalactosamine transmembrane transporter activity

SLC35D2 SLC35D1

3.95e-0521262GO:0005463
GeneOntologyMolecularFunctionnucleotide-sugar transmembrane transporter activity

SLC35D2 SLC35D1 SLC35D3

8.49e-05141263GO:0005338
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

PGA4 PGA5 CNTNAP5 PGA3

8.50e-05371264GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

PGA4 PGA5 CNTNAP5 PGA3

9.45e-05381264GO:0070001
GeneOntologyMolecularFunctionUDP-glucose transmembrane transporter activity

SLC35D2 SLC35D3

1.18e-0431262GO:0005460
GeneOntologyMolecularFunctionUDP-N-acetylglucosamine transmembrane transporter activity

SLC35D2 SLC35D1

3.90e-0451262GO:0005462
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC35D2 SLC35D1 SLC35D3 SLC29A4

5.26e-04591264GO:1901505
GeneOntologyMolecularFunctionnucleobase-containing compound transmembrane transporter activity

SLC35D2 SLC35D1 SLC35D3 SLC29A4

5.26e-04591264GO:0015932
GeneOntologyMolecularFunctioninterleukin-1 receptor activity

IL18RAP IL1R2

1.08e-0381262GO:0004908
GeneOntologyMolecularFunctioncell adhesion mediator activity

NTNG1 SVEP1 CNTN6 CXADR

1.37e-03761264GO:0098631
GeneOntologyMolecularFunctionDEAD/H-box RNA helicase binding

AKAP8L ZC3HAV1

1.38e-0391262GO:0017151
GeneOntologyMolecularFunctionendopeptidase activity

PCSK1 PCSK5 PGA4 ADAM32 PGA5 CNTNAP5 PCSK6 TMPRSS7 PGA3

1.64e-034301269GO:0004175
GeneOntologyBiologicalProcessUDP-N-acetylgalactosamine transmembrane transport

SLC35D2 SLC35D1

3.64e-0521252GO:0015789
GeneOntologyBiologicalProcessUDP-glucuronic acid transmembrane transport

SLC35D2 SLC35D1

3.64e-0521252GO:0015787
GeneOntologyBiologicalProcesspyrimidine nucleotide-sugar transmembrane transport

SLC35D2 SLC35D1 SLC35D3

4.59e-05121253GO:0090481
GeneOntologyBiologicalProcessnucleotide-sugar transmembrane transport

SLC35D2 SLC35D1 SLC35D3

5.94e-05131253GO:0015780
GeneOntologyCellularComponentmultivesicular body lumen

PGA4 PGA5 PGA3

7.53e-0671273GO:0097486
GeneOntologyCellularComponentlate endosome lumen

PGA4 PGA5 PGA3

3.49e-05111273GO:0031906
GeneOntologyCellularComponentgrowth cone

MAPK8IP1 MAP1B NCAM1 ALS2 TSC1 GDPD5 SHANK2 CXADR

1.28e-042451278GO:0030426
GeneOntologyCellularComponentsomatodendritic compartment

PCSK1 PCSK5 MAPK8IP1 ARHGAP32 HTR1D MAP1B ANKS1B NCAM1 ALS2 GDPD5 DIP2A NELL2 SHANK2 SACS KDR LYNX1 GRIN3B USH2A IL6ST

1.55e-04122812719GO:0036477
GeneOntologyCellularComponentsite of polarized growth

MAPK8IP1 MAP1B NCAM1 ALS2 TSC1 GDPD5 SHANK2 CXADR

1.60e-042531278GO:0030427
GeneOntologyCellularComponentdistal axon

PCSK1 MAPK8IP1 MAP1B NCAM1 ALS2 TSC1 GDPD5 SHANK2 USH2A CXADR

3.29e-0443512710GO:0150034
GeneOntologyCellularComponentcell body

PCSK1 PCSK5 MAPK8IP1 MAP1B NCAM1 ALS2 GDPD5 NELL2 SHANK2 KDR GRIN3B USH2A WNK4 IL6ST CXADR

5.22e-0492912715GO:0044297
GeneOntologyCellularComponentdendrite

PCSK1 PCSK5 MAPK8IP1 ARHGAP32 HTR1D MAP1B ANKS1B ALS2 DIP2A NELL2 SHANK2 SACS LYNX1 IL6ST

7.29e-0485812714GO:0030425
GeneOntologyCellularComponentdendritic tree

PCSK1 PCSK5 MAPK8IP1 ARHGAP32 HTR1D MAP1B ANKS1B ALS2 DIP2A NELL2 SHANK2 SACS LYNX1 IL6ST

7.45e-0486012714GO:0097447
GeneOntologyCellularComponenthippocampal mossy fiber

MAPK8IP1 MAP1B

7.54e-0471272GO:0097457
GeneOntologyCellularComponentside of membrane

NTNG1 NCAM1 CR2 CNTN6 SCUBE1 THADA ANTXR2 SMPDL3B KDR LYNX1 FCRL5 ATP2A2 KLRB1 IL6ST

8.81e-0487512714GO:0098552
GeneOntologyCellularComponentaxon

PCSK1 MAPK8IP1 MAP1B MYOC NCAM1 ALS2 TSC1 CNTN6 GDPD5 SHANK2 SACS USH2A ADGRL3 CXADR

1.05e-0389112714GO:0030424
GeneOntologyCellularComponentneuronal cell body

PCSK1 PCSK5 MAPK8IP1 MAP1B NCAM1 ALS2 GDPD5 NELL2 SHANK2 KDR GRIN3B USH2A IL6ST

1.72e-0383512713GO:0043025
DomainIg-like_fold

FNDC3B SEMA3C VSIG2 FSTL4 NCAM1 IL18RAP CNTN6 FNDC7 CD7 SHANK2 IL1R2 SIGIRR KDR ADGRF5 FCRL5 USH2A SDK1 GPA33 IL6ST CXADR

2.65e-0870612120IPR013783
Domain-

FNDC3B SEMA3C VSIG2 FSTL4 NCAM1 IL18RAP CNTN6 FNDC7 CD7 IL1R2 SIGIRR KDR ADGRF5 FCRL5 USH2A SDK1 GPA33 IL6ST CXADR

5.15e-08663121192.60.40.10
DomainIGc2

VSIG2 FSTL4 NCAM1 CNTN6 IL1R2 KDR ADGRF5 FCRL5 SDK1 GPA33 CXADR

3.75e-0723512111SM00408
DomainIg_sub2

VSIG2 FSTL4 NCAM1 CNTN6 IL1R2 KDR ADGRF5 FCRL5 SDK1 GPA33 CXADR

3.75e-0723512111IPR003598
DomainIG

SEMA3C VSIG2 FSTL4 NCAM1 IL18RAP CNTN6 CD7 IL1R2 KDR ADGRF5 FCRL5 SDK1 GPA33 CXADR

5.96e-0742112114SM00409
DomainIg_sub

SEMA3C VSIG2 FSTL4 NCAM1 IL18RAP CNTN6 CD7 IL1R2 KDR ADGRF5 FCRL5 SDK1 GPA33 CXADR

5.96e-0742112114IPR003599
DomainIG_LIKE

SEMA3C VSIG2 FSTL4 NCAM1 IL18RAP CNTN6 CD7 IL1R2 SIGIRR KDR ADGRF5 FCRL5 SDK1 GPA33 CXADR

6.71e-0749112115PS50835
DomainIg-like_dom

SEMA3C VSIG2 FSTL4 NCAM1 IL18RAP CNTN6 CD7 IL1R2 SIGIRR KDR ADGRF5 FCRL5 SDK1 GPA33 CXADR

9.08e-0750312115IPR007110
DomainEGF

PCSK5 FRAS1 NTNG1 LAMC1 ADAM32 SVEP1 NELL2 SCUBE1 CNTNAP5 PCSK6

3.07e-0623512110SM00181
DomainIg_I-set

SEMA3C VSIG2 FSTL4 NCAM1 CNTN6 KDR ADGRF5 SDK1 CXADR

4.09e-061901219IPR013098
DomainI-set

SEMA3C VSIG2 FSTL4 NCAM1 CNTN6 KDR ADGRF5 SDK1 CXADR

4.09e-061901219PF07679
DomainEGF-like_dom

PCSK5 FRAS1 NTNG1 LAMC1 ADAM32 SVEP1 NELL2 SCUBE1 CNTNAP5 PCSK6

5.13e-0624912110IPR000742
DomainPeptidase_S8_Asp-AS

PCSK1 PCSK5 PCSK6

5.23e-0661213IPR023827
Domain-

PCSK1 PCSK5 NTNG1 LAMC1 CNTNAP5 PCSK6

7.80e-067312162.60.120.260
DomainP_proprotein

PCSK1 PCSK5 PCSK6

9.11e-0671213PF01483
DomainS8_pro-domain

PCSK1 PCSK5 PCSK6

9.11e-0671213IPR032815
DomainPrprotnconvertsP

PCSK1 PCSK5 PCSK6

9.11e-0671213IPR002884
DomainAspartic_peptidase_N

PGA4 PGA5 PGA3

9.11e-0671213IPR012848
Domain-

PCSK1 PCSK5 PCSK6

9.11e-06712133.30.70.850
DomainS8_pro-domain

PCSK1 PCSK5 PCSK6

9.11e-0671213PF16470
DomainA1_Propeptide

PGA4 PGA5 PGA3

9.11e-0671213PF07966
DomainPeptidase_S8_His-AS

PCSK1 PCSK5 PCSK6

2.17e-0591213IPR022398
DomainPeptidase_S8_Ser-AS

PCSK1 PCSK5 PCSK6

2.17e-0591213IPR023828
DomainAspartic_peptidase_A1

PGA4 PGA5 PGA3

3.08e-05101213IPR001461
DomainSugar_P_trans_dom

SLC35D2 SLC35D1 SLC35D3

3.08e-05101213IPR004853
DomainPeptidase_S8_subtilisin-rel

PCSK1 PCSK5 PCSK6

3.08e-05101213IPR015500
DomainPEPTIDASE_A1

PGA4 PGA5 PGA3

3.08e-05101213IPR033121
DomainAsp

PGA4 PGA5 PGA3

3.08e-05101213PF00026
DomainPEPTIDASE_A1

PGA4 PGA5 PGA3

3.08e-05101213PS51767
DomainSUBTILASE_ASP

PCSK1 PCSK5 PCSK6

3.08e-05101213PS00136
DomainSUBTILASE_HIS

PCSK1 PCSK5 PCSK6

3.08e-05101213PS00137
DomainSUBTILASE_SER

PCSK1 PCSK5 PCSK6

3.08e-05101213PS00138
DomainTPT

SLC35D2 SLC35D1 SLC35D3

3.08e-05101213PF03151
DomainGalactose-bd-like

PCSK1 PCSK5 NTNG1 LAMC1 CNTNAP5 PCSK6

3.34e-05941216IPR008979
Domainig

FSTL4 NCAM1 IL1R2 KDR ADGRF5 FCRL5 GPA33 CXADR

3.34e-051901218PF00047
DomainImmunoglobulin

FSTL4 NCAM1 IL1R2 KDR ADGRF5 FCRL5 GPA33 CXADR

3.34e-051901218IPR013151
DomainIL-1_rcpt_fam

IL18RAP IL1R2 SIGIRR

4.21e-05111213IPR015621
Domain-

PCSK1 PCSK5 PCSK6

4.21e-051112133.40.50.200
DomainPeptidase_S8/S53_dom

PCSK1 PCSK5 PCSK6

4.21e-05111213IPR000209
DomainPeptidase_S8

PCSK1 PCSK5 PCSK6

4.21e-05111213PF00082
Domain-

PGA4 PGA5 PGA3

5.59e-051212132.40.70.10
DomainASP_PROTEASE

PGA4 PGA5 PGA3

5.59e-05121213PS00141
DomainGrowth_fac_rcpt_

PCSK5 FRAS1 LAMC1 SVEP1 NELL2 SCUBE1 PCSK6

7.06e-051561217IPR009030
DomainAspartic_peptidase_AS

PGA4 PGA5 PGA3

7.23e-05131213IPR001969
Domainfn3

FNDC3B NCAM1 CNTN6 FNDC7 USH2A SDK1 IL6ST

8.95e-051621217PF00041
DomainLaminin_N

NTNG1 LAMC1 USH2A

1.40e-04161213IPR008211
DomainLamNT

NTNG1 LAMC1 USH2A

1.40e-04161213SM00136
DomainLAMININ_NTER

NTNG1 LAMC1 USH2A

1.40e-04161213PS51117
DomainLaminin_N

NTNG1 LAMC1 USH2A

1.40e-04161213PF00055
DomainPropept_inh

PCSK1 PCSK5 PCSK6

1.69e-04171213IPR009020
DomainPeptidase_aspartic_dom

PGA4 PGA5 PGA3

1.69e-04171213IPR021109
DomainFurin_repeat

PCSK5 FRAS1 PCSK6

2.02e-04181213IPR006212
DomainFU

PCSK5 FRAS1 PCSK6

2.02e-04181213SM00261
DomainFN3

FNDC3B NCAM1 CNTN6 FNDC7 USH2A SDK1 IL6ST

2.04e-041851217SM00060
DomainEGF_1

NTNG1 LAMC1 ADAM32 SVEP1 NELL2 SCUBE1 CNTNAP5 USH2A

2.58e-042551218PS00022
DomainFN3

FNDC3B NCAM1 CNTN6 FNDC7 USH2A SDK1 IL6ST

3.18e-041991217PS50853
DomainFN3_dom

FNDC3B NCAM1 CNTN6 FNDC7 USH2A SDK1 IL6ST

4.27e-042091217IPR003961
DomainEphrin_rec_like

PCSK5 SVEP1 SCUBE1

5.50e-04251213SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

PCSK5 SVEP1 SCUBE1

5.50e-04251213IPR011641
DomainGF_recep_IV

PCSK5 PCSK6

6.14e-0461212PF14843
DomainGF_recep_IV

PCSK5 PCSK6

6.14e-0461212IPR032778
DomainEGF_LAM_2

NTNG1 LAMC1 USH2A

9.48e-04301213PS50027
DomainEGF_LAM_1

NTNG1 LAMC1 USH2A

9.48e-04301213PS01248
DomainIGv

VSIG2 CD7 GPA33 CXADR

1.43e-03751214SM00406
DomainEGF_Lam

NTNG1 LAMC1 USH2A

1.49e-03351213SM00180
DomainLaminin_EGF

NTNG1 LAMC1 USH2A

1.49e-03351213PF00053
DomainEGF_2

NTNG1 LAMC1 ADAM32 SVEP1 NELL2 SCUBE1 CNTNAP5

1.71e-032651217PS01186
DomainVPS9

GAPVD1 ALS2

1.81e-03101212PS51205
DomainVPS9

GAPVD1 ALS2

1.81e-03101212PF02204
DomainVPS9

GAPVD1 ALS2

1.81e-03101212IPR003123
DomainLaminin_EGF

NTNG1 LAMC1 USH2A

1.90e-03381213IPR002049
DomainLaminin_G_2

NELL2 CNTNAP5 USH2A

2.20e-03401213PF02210
DomainEphrin_rec_like

SVEP1 SCUBE1

2.20e-03111212PF07699
DomainLamG

NELL2 CNTNAP5 USH2A

2.89e-03441213SM00282
DomainOLF

MYOC ADGRL3

3.10e-03131212PF02191
DomainOLF

MYOC ADGRL3

3.10e-03131212PS51132
DomainOlfac-like_dom

MYOC ADGRL3

3.10e-03131212IPR003112
DomainOLF

MYOC ADGRL3

3.10e-03131212SM00284
Domain-

SVEP1 NELL2 CNTNAP5 USH2A

3.39e-039512142.60.120.200
DomainPLAC

PCSK5 PCSK6

3.60e-03141212PF08686
Domain-

ADGRF5 TMPRSS7

4.14e-031512123.30.70.960
DomainEGF_3

NTNG1 ADAM32 SVEP1 NELL2 SCUBE1 CNTNAP5

4.30e-032351216PS50026
DomainVWA

VIT SVEP1 ANTXR2

5.73e-03561213PF00092
DomainLaminin_G

NELL2 CNTNAP5 USH2A

6.32e-03581213IPR001791
PathwayREACTOME_SURFACTANT_METABOLISM

PGA4 PGA5 ADGRF5 PGA3

3.13e-0530864M27566
PathwayWP_GASTRIC_ACID_PRODUCTION

PGA4 PGA5 PGA3

3.49e-0511863M39726
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLC35D2 SLC35D1 SLCO4C1 SLC29A4

1.10e-0441864MM15075
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLC35D2 SLC35D1 SLCO4C1 SLC29A4

1.33e-0443864M881
Pubmed

The epidemiology of low serum pepsinogen A levels and an international association with gastric cancer rates. EUROGAST Study Group.

PGA4 PGA5 PGA3

4.76e-08312737926498
Pubmed

Crystal structure of human pepsinogen A.

PGA4 PGA5 PGA3

4.76e-08312739561228
Pubmed

The combination of serum trefoil factor 3 and pepsinogen testing is a valid non-endoscopic biomarker for predicting the presence of gastric cancer: a new marker for gastric cancer risk.

PGA4 PGA5 PGA3

4.76e-083127321455714
Pubmed

Serum pepsinogen level, atrophic gastritis and the risk of incident pancreatic cancer--a prospective cohort study.

PGA4 PGA5 PGA3

4.76e-083127319800305
Pubmed

Serum pepsinogen reference intervals in apparently healthy Chinese population with latex enhanced turbidimetric immunoassay.

PGA4 PGA5 PGA3

4.76e-083127324170207
Pubmed

Relationships between the human pepsinogen DNA and protein polymorphisms.

PGA4 PGA5 PGA3

4.76e-08312733014868
Pubmed

The ratio of pepsinogen A to pepsinogen C: a sensitive test for atrophic gastritis.

PGA4 PGA5 PGA3

4.76e-08312732799289
Pubmed

CRYSTALLINE PEPSIN : I. ISOLATION AND TESTS OF PURITY.

PGA4 PGA5 PGA3

4.76e-083127319872561
Pubmed

Human pepsinogen A (PGA): an informative gene complex located at 11q13.

PGA4 PGA5 PGA3

4.76e-08312731968039
Pubmed

Helicobacter pylori infection and serum pepsinogen A, pepsinogen C, and gastrin in gastritis and peptic ulcer: significance of inflammation and effect of bacterial eradication.

PGA4 PGA5 PGA3

4.76e-08312738053437
Pubmed

Family and population studies on the human pepsinogen A multigene family.

PGA4 PGA5 PGA3

4.76e-08312732566575
Pubmed

Immunoblot technique to visualise serum pepsinogen A isozymogen patterns.

PGA4 PGA5 PGA3

4.76e-08312732229438
Pubmed

Prediction of gastric cancer development by serum pepsinogen test and Helicobacter pylori seropositivity in Eastern Asians: a systematic review and meta-analysis.

PGA4 PGA5 PGA3

4.76e-083127325314140
Pubmed

Validation of the pepsinogen test method for gastric cancer screening using a follow-up study.

PGA4 PGA5 PGA3

4.76e-083127319890696
Pubmed

Diagnostic value of serum pepsinogen C in patients with raised serum concentrations of pepsinogen A.

PGA4 PGA5 PGA3

4.76e-08312738244094
Pubmed

Plasma pepsinogens, antibodies against Helicobacter pylori, and risk of gastric cancer in the Shanghai Women's Health Study Cohort.

PGA4 PGA5 PGA3

4.76e-083127321407214
Pubmed

Isolation of an activation intermediate and determination of the amino acid sequence of the activation segment of human pepsinogen A.

PGA4 PGA5 PGA3

4.76e-08312736774973
Pubmed

Primary structure of human pepsinogen gene.

PGA4 PGA5 PGA3

4.76e-08312736300126
Pubmed

Pepsinogen I/II ratio is related to glucose, triacylglycerol, and uric acid levels.

PGA4 PGA5 PGA3

4.76e-083127322304859
Pubmed

Pepsinogen I and II expressions in situ and their correlations with serum pesignogen levels in gastric cancer and its precancerous disease.

PGA4 PGA5 PGA3

4.76e-083127324004680
Pubmed

Effect of enprostil on serum gastrin and pepsinogen A and C levels in patients on long-term treatment with omeprazole.

PGA4 PGA5 PGA3

4.76e-08312738038355
Pubmed

Human pepsinogen A isozymogen patterns in serum and gastric mucosa.

PGA4 PGA5 PGA3

4.76e-08312732227273
Pubmed

Identification of a high risk gastric cancer group using serum pepsinogen after successful eradication of Helicobacter pylori.

PGA4 PGA5 PGA3

4.76e-083127323034090
Pubmed

A possible association of low pepsinogen I and pepsinogen I/II with low and high body weight in Japanese men.

PGA4 PGA5 PGA3

4.76e-083127324125879
Pubmed

Effects of omeprazole and lansoprazole on fasting and postprandial serum gastrin and serum pepsinogen A and C.

PGA4 PGA5 PGA3

4.76e-08312738751234
Pubmed

Enzyme-linked immunosorbent assay and radioimmunoassay of serum pepsinogen A.

PGA4 PGA5 PGA3

4.76e-08312733554488
Pubmed

Expression of serum miR-20a-5p, let-7a, and miR-320a and their correlations with pepsinogen in atrophic gastritis and gastric cancer: a case-control study.

PGA4 PGA5 PGA3

4.76e-083127323521833
Pubmed

Close linkage of human chromosomal pepsinogen A genes.

PGA4 PGA5 PGA3

4.76e-08312733017318
Pubmed

Serum pepsinogen test for early detection of gastric cancer in a European country.

PGA4 PGA5 PGA3

4.76e-083127321989121
Pubmed

Serum antibodies to H+,K+-ATPase, serum pepsinogen A and Helicobacter pylori in relation to gastric mucosa morphology in patients with low or low-normal concentrations of serum cobalamins.

PGA4 PGA5 PGA3

4.76e-08312739855083
Pubmed

Advantages of serum pepsinogen A combined with gastrin or pepsinogen C as first-line analytes in the evaluation of suspected cobalamin deficiency: a study in patients previously not subjected to gastrointestinal surgery.

PGA4 PGA5 PGA3

4.76e-08312739797498
Pubmed

The glomerular sieving of pepsinogen A and C in man.

PGA4 PGA5 PGA3

4.76e-08312732478370
Pubmed

Clinical significance of pepsinogen A isozymogens, serum pepsinogen A and C levels, and serum gastrin levels.

PGA4 PGA5 PGA3

4.76e-08312733815274
Pubmed

Pepsinogens: physiology, pharmacology pathophysiology and exercise.

PGA4 PGA5 PGA3

4.76e-083127310675278
Pubmed

Pepsinogen A polymorphism in gastric mucosa and urine, with special reference to patients with gastric cancer.

PGA4 PGA5 PGA3

4.76e-08312733780036
Pubmed

Identification of a Glu greater than Lys substitution in the activation segment of human pepsinogen A-3 and -5 isozymogens by peptide mapping using endoproteinase Lys-C.

PGA4 PGA5 PGA3

4.76e-08312732901984
Pubmed

Assignment of human pepsinogen A locus to the q12-pter region of chromosome 11.

PGA4 PGA5 PGA3

4.76e-08312733839486
Pubmed

Assignment of the pepsinogen gene complex (PGA) to human chromosome region 11q13 by in situ hybridization.

PGA4 PGA5 PGA3

4.76e-08312733467902
Pubmed

The pepsinogens of human gastric mucosa.

PGA4 PGA5 PGA3

4.76e-08312734586732
Pubmed

Genomic structure and evolution of the human pepsinogen A multigene family.

PGA4 PGA5 PGA3

4.76e-08312732892778
Pubmed

The value of serum pepsinogen levels for the diagnosis of gastric diseases in Chinese Han people in midsouth China.

PGA4 PGA5 PGA3

4.76e-083127324383519
Pubmed

Gene structures of pepsinogens A and C.

PGA4 PGA5 PGA3

4.76e-08312731455184
Pubmed

Hypomethylation and expression of pepsinogen A genes in the fundic mucosa of human stomach.

PGA4 PGA5 PGA3

4.76e-08312732831884
Pubmed

Localization of pepsinogen (A and C) and cellular differentiation of pepsinogen-synthesizing cells in the human gastric mucosa.

PGA4 PGA5 PGA3

4.76e-08312732032552
Pubmed

Analysis of the promoter of a human pepsinogen A gene.

PGA4 PGA5 PGA3

4.76e-08312731812762
Pubmed

O6-methylguanine in blood leucocyte DNA: an association with the geographic prevalence of gastric cancer and with low levels of serum pepsinogen A, a marker of severe chronic atrophic gastritis. The EUROGAST Study Group.

PGA4 PGA5 PGA3

4.76e-08312737923573
Pubmed

Fast detection of phosphorylation of human pepsinogen A, human pepsinogen C and swine pepsinogen using a combination of reversed-phase high-performance liquid chromatography and capillary zone electrophoresis for peptide mapping.

PGA4 PGA5 PGA3

4.76e-08312739061458
Pubmed

Ratio between serum IL-8 and pepsinogen A/C: a marker for atrophic body gastritis.

PGA4 PGA5 PGA3

4.76e-083127312588289
Pubmed

Gastric cancer detection using gastric juice pepsinogen and melanoma-associated gene RNA.

PGA4 PGA5 PGA3

4.76e-083127323897256
Pubmed

An aspartic proteinase expressed in the yolk sac and neonatal stomach of the mouse.

PGA4 PGA5 PGA3

4.76e-083127311566730
Pubmed

The effect of acute and chronic protein loading on urinary pepsinogen A excretion.

PGA4 PGA5 PGA3

4.76e-08312731956484
Pubmed

Transcription regulation of human and porcine pepsinogen A.

PGA4 PGA5 PGA3

4.76e-08312738540382
Pubmed

Exploratory findings of audiometry in adult patients with otitis media with high pepsinogen concentrations: a preliminary study.

PGA4 PGA5 PGA3

4.76e-083127322992016
Pubmed

The role of serum pepsinogen in the detection of gastric cancer.

PGA4 PGA5 PGA3

4.76e-083127320981206
Pubmed

Gastric chief cell-specific transcription of the pepsinogen A gene.

PGA4 PGA5 PGA3

4.76e-08312738504820
Pubmed

Detection of pepsinogen in the neonatal lung and stomach by immunohistochemistry.

PGA4 PGA5 PGA3

4.76e-083127321970995
Pubmed

Serum pepsinogens in gastric cancer screening.

PGA4 PGA5 PGA3

4.76e-083127320428942
Pubmed

The relationship of Helicobacter pylori colonization, the serum pepsinogen A level, and gastric resection.

PGA4 PGA5 PGA3

4.76e-08312739525001
Pubmed

Evaluation of pepsinogen A and gastrin-17 as markers of gastric cancer and high-risk pathologic conditions.

PGA4 PGA5 PGA3

4.76e-08312737886402
Pubmed

Serum pepsinogen and gastric cancer screening.

PGA4 PGA5 PGA3

4.76e-083127317379991
Pubmed

Low serum pepsinogen I and pepsinogen I/II ratio and Helicobacter pylori infection are associated with increased risk of gastric cancer: 14-year follow up result in a rural Chinese community.

PGA4 PGA5 PGA3

4.76e-083127321547904
Pubmed

Serum pepsinogen I/II ratio is correlated with albuminuria in patients with type 2 diabetes.

PGA4 PGA5 PGA3

1.90e-074127323047493
Pubmed

Pepsinogens, progastricsins, and prochymosins: structure, function, evolution, and development.

PGA4 PGA5 PGA3

1.90e-074127311915945
Pubmed

Pepsinogen A and C serum levels in relation to acute NSAID-associated mucosal lesions in healthy volunteers.

PGA4 PGA5 PGA3

1.90e-07412738322031
Pubmed

Transcription factor SOX2 up-regulates stomach-specific pepsinogen A gene expression.

PGA4 PGA5 PGA3

1.90e-074127317136346
Pubmed

Pepsinogen A, pepsinogen C, and gastrin as markers of atrophic chronic gastritis in European dyspeptics.

PGA4 PGA5 PGA3

1.90e-074127312698190
Pubmed

Processing of prothyrotropin-releasing hormone by the family of prohormone convertases.

PCSK1 PCSK5 PCSK6

4.73e-07512739242664
Pubmed

Accuracy and cut-off values of pepsinogens I, II and gastrin 17 for diagnosis of gastric fundic atrophy: influence of gastritis.

PGA4 PGA5 PGA3

4.73e-075127322066020
Pubmed

Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network.

PCSK5 OAS3 SCUBE1 SHANK2

6.30e-0719127423149075
Pubmed

Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines.

PCSK1 PCSK5 PCSK6

9.43e-07612738940009
Pubmed

Murine subtilisin-like proteinase SPC6 is expressed during embryonic implantation, somitogenesis, and skeletal formation.

PCSK1 PCSK5 PCSK6

9.43e-07612739291583
Pubmed

Proteolytic processing in the secretory pathway.

PCSK1 PCSK5 PCSK6

1.65e-067127310409610
Pubmed

The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.

PCSK1 PCSK5 PCSK6

1.65e-06712737819324
Pubmed

Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.

PCSK1 PCSK5 PCSK6

2.63e-06812739885250
Pubmed

Cellular localization and role of prohormone convertases in the processing of pro-melanin concentrating hormone in mammals.

PCSK1 PCSK5 PCSK6

2.63e-068127310037747
Pubmed

The activation and physiological functions of the proprotein convertases.

PCSK1 PCSK5 PCSK6

3.93e-069127318343183
Pubmed

The biology and therapeutic targeting of the proprotein convertases.

PCSK1 PCSK5 PCSK6

3.93e-069127322679642
Pubmed

The prohormone theory and the proprotein convertases: it is all about serendipity.

PCSK1 PCSK5 PCSK6

3.93e-069127321805236
Pubmed

The proprotein convertases, 20 years later.

PCSK1 PCSK5 PCSK6

3.93e-069127321805237
Pubmed

The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions.

PCSK1 PCSK5 PCSK6

3.93e-069127323775089
Pubmed

SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis.

PCSK1 PCSK5 PCSK6

3.93e-06912738698813
Pubmed

Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development.

PCSK1 PCSK5 PCSK6

5.60e-0610127316163737
Pubmed

Nucleotide sequence comparison of five human pepsinogen A (PGA) genes: evolution of the PGA multigene family.

PGA4 PGA5

1.32e-05212722714789
Pubmed

Activation of human pepsinogens.

PGA4 PGA5

1.32e-05212723197840
Pubmed

Crystal structure of human pepsin and its complex with pepstatin.

PGA4 PGA5

1.32e-05212727663352
Pubmed

Cell-surface processing of extracellular human immunodeficiency virus type 1 Vpr by proprotein convertases.

PCSK5 PCSK6

1.32e-052127218061232
Pubmed

ANTXR2 and IL-1R2 polymorphisms are not associated with ankylosing spondylitis in Chinese Han population.

ANTXR2 IL1R2

1.32e-052127220652271
Pubmed

Identification of an isoform with an extremely large Cys-rich region of PC6, a Kex2-like processing endoprotease.

PCSK5 PCSK6

1.32e-05212728335106
Pubmed

Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4.

PCSK5 PCSK6

1.32e-05212728468318
Pubmed

Isolation of human, swine, and rat prepepsinogens and calf preprochymosin, and determination of the primary structures of their NH2-terminal signal sequences.

PGA4 PGA5

1.32e-05212722415509
Pubmed

DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing.

MAP1B DAPK1

1.32e-052127218195017
Pubmed

A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa.

HTR1D NTNG1 CNTN6

1.32e-0513127321079607
Pubmed

Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst.

PCSK1 PCSK5 PCSK6

2.57e-0516127320876279
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PCSK5 FNDC3B SEMA3C FRAS1 PDE3B ATRX MAP1B EWSR1 AKAP8L DIP2A ZC3HAV1

2.80e-056501271138777146
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

VSIG2 FSTL4 CNTN6 KDR ADGRF5 CXADR

3.02e-05162127625826454
Pubmed

Glypican-6 and Glypican-4 stimulate embryonic stomach growth by regulating Hedgehog and noncanonical Wnt signaling.

PGA4 PGA5 PGA3

3.73e-0518127336057966
Pubmed

Hereditary spastic paraplegias: identification of a novel SPG57 variant affecting TFG oligomerization and description of HSP subtypes in Sudan.

ALS2 SACS

3.96e-053127227601211
Pubmed

Genetic studies of ankylosing spondylitis in Koreans confirm associations with ERAP1 and 2p15 reported in white patients.

ANTXR2 IL1R2

3.96e-053127221041274
Pubmed

Loss of neural recognition molecule NB-3 delays the normal projection and terminal branching of developing corticospinal tract axons in the mouse.

NCAM1 CNTN6

3.96e-053127221935948
Pubmed

Comparative cellular processing of the human immunodeficiency virus (HIV-1) envelope glycoprotein gp160 by the mammalian subtilisin/kexin-like convertases.

PCSK5 PCSK6

3.96e-05312728670066
GeneFamilyImmunoglobulin like domain containing

FSTL4 IL18RAP IL1R2 SIGIRR KDR ADGRF5 FCRL5 SDK1 GPA33 CXADR

3.34e-081938810594
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

SEMA3C VSIG2 FSTL4 NCAM1 CNTN6 KDR ADGRF5 SDK1

1.17e-06161888593
GeneFamilyProprotein convertase subtilisin/kexin family

PCSK1 PCSK5 PCSK6

9.16e-069883973
GeneFamilyFibronectin type III domain containing

FNDC3B NCAM1 CNTN6 FNDC7 USH2A SDK1 IL6ST

1.30e-05160887555
GeneFamilyADAM metallopeptidase domain containing|CD molecules

NCAM1 LAMP2 CR2 IL18RAP CD7 IL1R2 KDR FCRL5 KLRB1 IL6ST

2.14e-053948810471
GeneFamilySolute carriers

SLC35D2 SLC35D1 SLCO4C1 SLC35D3 SLC25A44 SLC5A8 SLC29A4 SLC44A3

6.78e-04395888752
GeneFamilyVPS9 domain containing

GAPVD1 ALS2

1.03e-0310882928
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL18RAP IL1R2 IL6ST

1.12e-0342883602
GeneFamilyAdenosine receptors|V-set domain containing

VSIG2 CD7 KDR GPA33 CXADR

1.20e-03163885590
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL18RAP SIGIRR

2.36e-03158821296
GeneFamilyNLR family

NLRC4 NLRP4

6.53e-0325882666
GeneFamilyAnkyrin repeat domain containing

ANKS1B DAPK1 SHANK2 AGAP7P AGAP4

6.56e-03242885403
CoexpressionHAHTOLA_SEZARY_SYNDROM_DN

NCAM1 IL18RAP NELL2 VAV3 KLRB1

2.05e-06431275M18968
CoexpressionNABA_ECM_GLYCOPROTEINS

FRAS1 NTNG1 LAMC1 VIT SVEP1 NELL2 FNDC7 USH2A

5.31e-061961278M3008
CoexpressionGSE22886_CD8_TCELL_VS_BCELL_NAIVE_UP

SLC35D2 NELL2 CD7 DENND1B SACS SIGIRR SLC25A44 KLRB1

5.94e-061991278M4427
CoexpressionDESCARTES_FETAL_HEART_LYMPHOID_CELLS

CR2 IL18RAP CD7 FCRL5 KLRB1 GPA33

1.90e-051131276M40195
CoexpressionGOZGIT_ESR1_TARGETS_DN

SEMA3C FRAS1 WIPI1 RUBCNL SGK3 DIP2A NELL2 DENND1B SHANK2 PCSK6 KDR VAV3 MPPED2 SDK1

2.87e-0578612714M10961
CoexpressionNABA_ECM_GLYCOPROTEINS

FRAS1 NTNG1 LAMC1 VIT SVEP1 NELL2 FNDC7

4.18e-051911277MM17059
CoexpressionGSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_DN

PDE3B WDR70 ALS2 TSC1 IL18RAP NBAS NELL2

5.08e-051971277M8271
CoexpressionGSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_DN

PCSK5 IL18RAP FRMD4B SLC35D1 SLC25A44 ATP2A2 PHLPP2

5.25e-051981277M6068
CoexpressionGSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN

ANKS1B NTNG1 VIT SVEP1 CCDC136 IL6ST SLC44A3

5.42e-051991277M6066
CoexpressionGSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_STIM_DN

SLC35D2 VPS50 CNTN6 SLC35D3 TIFA LYNX1 PHLPP2

5.59e-052001277M8001
CoexpressionNABA_CORE_MATRISOME

FRAS1 NTNG1 LAMC1 VIT SVEP1 NELL2 FNDC7 USH2A

6.05e-052751278M5884
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

FNDC3B ARHGAP32 PDE3B ANKS1B LAMC1 VIT SVEP1 PCSK6 ADGRL3

5.11e-091951279ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellLA|World / Chamber and Cluster_Paper

PCSK5 MAP1B ANKS1B LAMC1 VIT SVEP1 PCSK6 SDK1

8.59e-081931278d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

FNDC3B ANKS1B LAMC1 VIT SVEP1 ANTXR2 PCSK6 ADGRL3

9.30e-081951278f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FSTL4 NTNG1 DAPK1 NELL2 CNTNAP5 ANTXR2 VAV3 CCDC136

9.30e-081951278787e95fb59c40bba784544b662fac37606ae1427
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 DAPK1 DENND1B SHANK2 VAV3 MPPED2 SDK1 CXADR

9.67e-081961278c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_late|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

VSIG2 DAPK1 NELL2 SMPDL3B SHANK2 ADGRF5 CXADR SLC44A3

1.05e-0719812781851b7f4198b42c21c934e2fbda39dbd65e2625c
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK1 FRAS1 ANKS1B UNC93A CNTN6 CNTNAP5 USH2A

4.28e-071621277bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellTCGA-Lung-Solid_Tissue_Normal|TCGA-Lung / Sample_Type by Project: Shred V9

MYOC SOX17 NLRC4 CNTN6 SCUBE1 ANGPTL7 GPA33

5.05e-071661277a8ebdd3cb7f59b3feeaacda45ce6d40d10db556f
ToppCellTCGA-Lung-Solid_Tissue_Normal-Lung|TCGA-Lung / Sample_Type by Project: Shred V9

MYOC SOX17 NLRC4 CNTN6 SCUBE1 ANGPTL7 GPA33

5.05e-071661277c64971c27cb445dffc5a636d4b6a60261b93a2db
ToppCellTCGA-Lung-Solid_Tissue_Normal-Lung-Lung_normal_tissue|TCGA-Lung / Sample_Type by Project: Shred V9

MYOC SOX17 NLRC4 CNTN6 SCUBE1 ANGPTL7 GPA33

5.05e-0716612772f3072a7af048f184d33065fdd36153fd563155a
ToppCellTCGA-Lung-Solid_Tissue_Normal-Lung-Lung_normal_tissue-6|TCGA-Lung / Sample_Type by Project: Shred V9

MYOC SOX17 NLRC4 CNTN6 SCUBE1 ANGPTL7 GPA33

5.05e-071661277188f2575511f418216874aed9118aa6f165252cb
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NCAM1 IL18RAP DIP2A CD7 SIGIRR VAV3 KLRB1

6.93e-07174127733d6b81f31bfcb9c4b30206d88e20b9a94fba4a2
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C HTR1D MYOC VIT CNTN6 NELL2 FCRL5

8.71e-0718012773d95232b5785c705f41e01e3ffe0fa8dce1ff0a7
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C HTR1D MYOC VIT CNTN6 NELL2 FCRL5

8.71e-07180127747e345359064dc8ceec982b062e47802e728b43f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCSK5 FRAS1 RUBCNL ANKS1B NELL2 MPPED2 SLC44A3

9.37e-071821277ecb5624c9074cc6449fad961df54c926c2681d54
ToppCellIPF-Lymphoid-ILC_A|World / Disease state, Lineage and Cell class

NCAM1 IL18RAP SLC35D1 DIP2A CD7 VAV3 KLRB1

9.37e-071821277f91bb45baaec76cb3bb26eedbcf0709b2492e93f
ToppCellIPF-Lymphoid-ILC_A|IPF / Disease state, Lineage and Cell class

NCAM1 IL18RAP SLC35D1 DIP2A CD7 VAV3 KLRB1

9.72e-07183127749bfeaae13eb236f61a5486ee75c39789936bb8a
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_bright-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

FRAS1 NCAM1 IL18RAP SLC35D1 CD7 KLRB1 SLC29A4

1.05e-0618512773b2da51aec057b462749ae39afb8f253afcf38d5
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

PCSK5 PDE3B ANKS1B LAMC1 VIT SVEP1 PCSK6

1.12e-0618712774ea486991f66c29728d127171a07b81404ec0b78
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANKS1B LAMC1 VIT SVEP1 ANTXR2 PCSK6 ADGRL3

1.16e-061881277fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SEMA3C FRAS1 SMPDL3B SHANK2 VAV3 CXADR SLC44A3

1.25e-061901277625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

FNDC3B PDE3B LAMC1 VIT SVEP1 PCSK6 ADGRL3

1.29e-061911277d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

FNDC3B ANKS1B LAMC1 VIT SVEP1 PCSK6 ADGRL3

1.29e-06191127770c067c54084bfb02c29bab085f4defd477194fb
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FSTL4 DIPK1B PCSK6 KDR VAV3 MPPED2 ADGRL3

1.34e-0619212777197e401e563441ab94815f7619e032ebef9e586
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-NK|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NCAM1 IL18RAP DIP2A CD7 VAV3 KLRB1 ZC3HAV1

1.34e-061921277a06d5d3c2537f8d2b1dc6b6f3e88a80b5c2a1850
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

FNDC3B PDE3B ANKS1B LAMC1 VIT SVEP1 ADGRL3

1.44e-06194127711c79a8c56ece42713b04b321982e41e239f07a5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 DAPK1 SHANK2 SLCO4C1 VAV3 MPPED2 SLC44A3

1.44e-06194127793c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

PCSK5 PDE3B ANKS1B LAMC1 VIT SVEP1 PCSK6

1.49e-061951277a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell10x5'-lymph-node_spleen-Lymphocytic_NK-NK_CD16|lymph-node_spleen / Manually curated celltypes from each tissue

FNDC3B NCAM1 IL18RAP DIP2A CD7 SLCO4C1 KLRB1

1.54e-061961277f7e5a7fad4547e8ab9ab8b140239281832fb4260
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-natural_killer_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NCAM1 IL18RAP DIP2A CD7 SLCO4C1 VAV3 KLRB1

1.59e-061971277550cce374332c49893bcf4ce4b7dceb7f5fe26aa
ToppCellmLN-B_cell-B_cell_IgG_Plasma|B_cell / Region, Cell class and subclass

FNDC3B WIPI1 DAPK1 IGLV3-1 SMPDL3B FCRL5 SLC44A3

1.59e-061971277bd1d01d6c49f68f5c85d84df96c90dd04b9de09b
ToppCell(0)_NK_FCGR3Apos|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PCSK5 NCAM1 IL18RAP DIP2A CD7 SLCO4C1 KLRB1

1.64e-06198127713f10f9233fc1523f0da2d9d59f3ced9c51a603a
ToppCellNS-critical-d_07-13|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARHGAP32 SEMA3C VSIG2 PITX1 LYNX1 SLC5A8 CXADR

1.64e-061981277a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

VSIG2 DAPK1 NELL2 SMPDL3B SHANK2 CXADR SLC44A3

1.64e-061981277c477405b093f4e5374e57bcacf1fb204a0f7eb3b
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-natural_killer_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NCAM1 IL18RAP DIP2A CD7 SLCO4C1 VAV3 KLRB1

1.64e-0619812775607e36f393cb399fcc2504502498453fd32d96b
ToppCellCaecum-T_cell-Treg|Caecum / Region, Cell class and subclass

ANKS1B FRMD4B CD7 IL1R2 VAV3 KLRB1 IL6ST

1.70e-061991277ab0b32c077ac26d32a293dcf686af6984980793f
ToppCellCaecum-(1)_T_cell-(15)_Treg|Caecum / shred on region, Cell_type, and subtype

ANKS1B FRMD4B CD7 IL1R2 VAV3 KLRB1 IL6ST

1.70e-06199127712c22b07a231c9dc548e9dc37e0a60296a4a6273
ToppCellNeuron-Postmitotic-Excitatory_Neuron_|World / Primary Cells by Cluster

SEMA3C ATRX MAP1B NCAM1 FRMD4B NELL2 CXADR

1.70e-061991277058373b4ac3cec2108cb24265628ff0a50646e33
ToppCellsevere-NK_CD56bright|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FRAS1 NCAM1 IL18RAP CD7 VAV3 KLRB1 SLC29A4

1.76e-06200127782818ab1796fdd0b8be02b341818897595eed841
ToppCellURO-Lymphocyte-T_NK-NK_CD56bright|URO / Disease, Lineage and Cell Type

NCAM1 IL18RAP CD7 ANGPTL7 KLRB1 SLC29A4

4.10e-061471276a6ca90e8dc37a016572ff68f34ab227b020eef70
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Trm_Tgd|lymph-node_spleen / Manually curated celltypes from each tissue

NCAM1 IL18RAP SCUBE1 CD7 SLCO4C1 KLRB1

5.36e-06154127651ffb3fa0250bd31be764ed048728aa064056e16
ToppCellBronchial_Brush-Epithelial-Goblet_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

FRAS1 VSIG2 FSTL4 PCDHB4 LYNX1 PHLPP2

6.44e-061591276a8fa49dc2e6ad726d1f4f2b30693fecd1151a485
ToppCellBronchial_Brush-Epithelial-Goblet_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

FRAS1 VSIG2 FSTL4 PCDHB4 LYNX1 PHLPP2

6.44e-06159127695834b767cfb4fb8c5aeea89c10f3e14a1fd15c1
ToppCellcontrol-NK_CD56bright|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FRAS1 NCAM1 TOGARAM1 IL18RAP CD7 KLRB1

6.67e-061601276f49c810072604c4dee51025073c9e088c00daf4a
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PCSK1 ARHGAP32 FRAS1 NTNG1 NELL2 TMPRSS7

6.92e-061611276ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCell390C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ZNF507 DIPK1B NCAM1 CD7 ADGRF5 MPPED2

7.17e-06162127645be019b50e3727fc9d3fad2ff78e74e4f2d746b
ToppCell390C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ZNF507 DIPK1B NCAM1 CD7 ADGRF5 MPPED2

7.17e-061621276fbb0cc2b1434a340dc35058b77c73ea61004c252
ToppCellTCGA-Stomach-Solid_Tissue_Normal-Stomach_normal_tissue-Stomach_normal_tissue-7|TCGA-Stomach / Sample_Type by Project: Shred V9

MYOC ANKS1B NCAM1 SCUBE1 MPPED2 ANGPTL7

7.17e-061621276b115b5799137122bd60696f8ae2aebadad6cd044
ToppCell10x5'-blood-Lymphocytic_NK-NK_CD56bright_CD16-|blood / Manually curated celltypes from each tissue

FRAS1 NCAM1 IL18RAP CD7 SMPDL3B KLRB1

8.24e-061661276ba42349a68b22e91a0340bda1ccecd6c7592392f
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

VSIG2 SHANK2 SLCO4C1 ADGRF5 SLC5A8 CXADR

8.82e-061681276e20e1936573fdde78426d7a4eb45c458d5c4dbb4
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

VSIG2 SHANK2 SLCO4C1 ADGRF5 SLC5A8 CXADR

8.82e-06168127616b517e3159ad6e6d25fd48f7d5f46e77b2b318d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FNDC3B NTNG1 GMNC ANTXR2 ADGRF5 VAV3

9.12e-061691276319cba07263bf41fcbcbfecd117f91b729394241
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-natural_killer_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

WIPI1 NCAM1 IL18RAP SLC35D1 CD7 KLRB1

1.01e-05172127668fd03f2c8ee01fe46194400f74ede3830e00f34
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-NK_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FSTL4 IL18RAP CD7 AGAP4 KLRB1 SLC44A3

1.01e-051721276a126dacd94939851de1403d30f0b63eaad48bfa1
ToppCellCOPD-Lymphoid-ILC_A|World / Disease state, Lineage and Cell class

NCAM1 IL18RAP SLC35D1 CD7 VAV3 KLRB1

1.11e-051751276e773e330de36f8a0aa9398a176ed7edb5599c582
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA3C FRAS1 ANKS1B VIT ANGPTL7 CXADR

1.15e-0517612768e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA3C FRAS1 ANKS1B VIT ANGPTL7 CXADR

1.15e-051761276ed575330a08a6748ea4b28433292c8cfd157d444
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTNG1 GMNC CNTNAP5 ANTXR2 ADGRF5 VAV3

1.15e-05176127640993c41c1017b53039a337174fc56632b278609
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTNG1 GMNC CNTNAP5 ANTXR2 ADGRF5 VAV3

1.19e-051771276f902600c639087664316b3cf30cab243bc3d1c5c
ToppCellControl|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 PDE3B CNTN6 KDR MPPED2 ADGRL3

1.19e-051771276b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRAS1 RUBCNL ANKS1B NELL2 MPPED2 SLC44A3

1.19e-051771276d05497d2c80a66ec6a4e1733fea3a5534877a6a7
ToppCellHealthy_Control-Lymphoid-NK-NK|Healthy_Control / Condition, Lineage, Cell class and cell subclass

NCAM1 CD7 KLRB1 CCDC136 SLC29A4 TRAV18

1.23e-05178127671e99f143009b2d29cb47b96393b58b514c8cfc6
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK8IP1 MAP1B SLC35D3 ADGRF5 CCDC136 SLC29A4

1.23e-05178127630ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 MAP1B ZNF507 KDR ADGRF5 IL6ST

1.27e-051791276025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKS1B NCAM1 KDR ADGRF5 FCRL5 SLC29A4

1.31e-051801276dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKS1B NCAM1 KDR ADGRF5 FCRL5 SLC29A4

1.31e-051801276423454e3390080ae03bb3cbb267255ebfe4df080
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAP1B ANKS1B LAMC1 VIT SVEP1 ADGRL3

1.39e-051821276fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK1 VSIG2 NTNG1 NELL2 ANTXR2 VAV3

1.48e-0518412766475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP32 SEMA3C DAPK1 NELL2 SHANK2 SLC44A3

1.53e-0518512760d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAP1B LAMC1 VIT SVEP1 PCSK6 ADGRL3

1.53e-0518512768f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellnormal-na-Lymphocytic_NK-NK_dim-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

NCAM1 IL18RAP DIP2A CD7 VAV3 KLRB1

1.53e-051851276b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCellCOVID-19_Moderate-NK_activated|World / disease group, cell group and cell class

OAS3 NCAM1 CD7 SLCO4C1 SIGIRR KLRB1

1.57e-051861276ff8f32f69516bf785224fa12f8139a95359b0279
ToppCellPCW_05-06-Endothelial-Endothelial_mature-lymphatic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SOX17 GDPD5 PCSK6 KDR ADGRF5 VAV3

1.57e-05186127686b218a400f9c64f92b050f00b49f09647b17437
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 DAPK1 CNTN6 SHANK2 EML5 CXADR

1.57e-0518612764e94158db52df41d71e67b02b9895a358eebee0f
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GDPD5 PCSK6 KDR ADGRF5 VAV3 CXADR

1.57e-0518612765d94e6dd2c92e0c46badeb1e6eb54b69af855a66
ToppCellPCW_05-06-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SOX17 GDPD5 PCSK6 KDR ADGRF5 VAV3

1.57e-051861276f51c76b1c3c6c49e0ebc9a913d8413e0b6a04d80
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GDPD5 PCSK6 KDR ADGRF5 VAV3 CXADR

1.57e-0518612761da52e13096dfe4eb08bd0e7461cb3809b3b3deb
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NCAM1 IL18RAP DIP2A CD7 SLCO4C1 KLRB1

1.62e-0518712760bca79cea4886b66350c56c61859bd71e1e7a85c
ToppCellP03-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX17 NHLRC2 KDR ADGRF5 VAV3 MPPED2

1.62e-05187127655618ceec367c1c51ed5c447063d7fbd5c7e0808
ToppCellCOPD-Lymphoid-NK|COPD / Disease state, Lineage and Cell class

NCAM1 IL18RAP DIP2A CD7 VAV3 KLRB1

1.67e-051881276c9a227c8e71b69929d43e9afb8306a95c8163778
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B NELL2 CD7 KLRB1 IL6ST ZC3HAV1

1.72e-0518912769ab77c6fcb573854da5922412f53d2168bda6b58
ToppCellEC-Sinusoidal_ECs|World / Lineage and Cell class

VSIG2 SOX17 KDR ADGRF5 IL6ST CXADR

1.72e-0518912769a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCellCOPD-Lymphoid-NK|World / Disease state, Lineage and Cell class

NCAM1 IL18RAP DIP2A CD7 VAV3 KLRB1

1.72e-051891276c0ac160fa7e68b92414fb1600abcac8ad1a42232
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B NELL2 CD7 KLRB1 IL6ST ZC3HAV1

1.72e-0518912765a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCellIPF-Lymphoid-NK|IPF / Disease state, Lineage and Cell class

NCAM1 IL18RAP DIP2A CD7 VAV3 KLRB1

1.72e-051891276d92e880162450f8d01e4b8784eb625275cb8e03e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B DIP2A NELL2 CD7 IL6ST ZC3HAV1

1.72e-051891276e9df7ecd36bee1fedce23bb188c68a94fa60462c
ToppCellControl-Lymphoid-NK|World / Disease state, Lineage and Cell class

NCAM1 IL18RAP DIP2A CD7 VAV3 KLRB1

1.72e-05189127689ef0d0e66dc96cacaae6be7aacdaa884e8e66a8
ToppCellLPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B SOX17 PCSK6 KDR ADGRF5 ADGRL3

1.72e-051891276e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B SOX17 ANTXR2 KDR VAV3 ADGRL3

1.72e-0518912765d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCellCOVID-19-T_cells-NK_cells|COVID-19 / group, cell type (main and fine annotations)

NCAM1 IL18RAP DIP2A CD7 VAV3 KLRB1

1.72e-051891276b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX17 DIPK1B CALHM4 GDPD5 KDR ADGRF5

1.77e-05190127692fdfed12061ee9f6c7171cf8a7f3344921f2d40
ToppCellP03-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX17 NHLRC2 KDR ADGRF5 VAV3 MPPED2

1.77e-051901276347c7bf67ade235a4e2320db6a75ce0dab8744f9
ToppCellControl-Lymphoid-NK|Lymphoid / Disease state, Lineage and Cell class

FNDC3B NCAM1 DIP2A CD7 VAV3 KLRB1

1.77e-0519012761584c68b58c7f406d9b0e8451beea3e6f8980c56
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA3C GAPVD1 ATRX MAP1B ADGRF5 ADGRL3

1.77e-051901276d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

FNDC3B ANKS1B LAMC1 VIT SVEP1 ADGRL3

1.77e-05190127612992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellASK428-Immune-NK_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

NCAM1 EWSR1 IL18RAP CD7 SIGIRR KLRB1

1.77e-051901276d649f7e17c4227787465dfc02037f791ff85378b
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

FRAS1 PDE3B NTNG1 NCAM1 FRMD4B NELL2

1.77e-05190127671e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTNG1 DAPK1 CNTNAP5 ANTXR2 VAV3 CCDC136

1.77e-0519012761bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCellCOVID-19-Heart-T_cell|Heart / Disease (COVID-19 only), tissue and cell type

FSTL4 IL18RAP CNTNAP5 CD7 SHANK2 SLCO4C1

1.77e-051901276e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCellControl-Lymphoid-NK|Control / Disease state, Lineage and Cell class

NCAM1 IL18RAP DIP2A CD7 VAV3 KLRB1

1.77e-051901276f7bd8521a40ac30a64dc439f17e2f6c7d021ef65
Drugpyriproxyfen

ARHGAP32 RFX1 ANTXR2 SLC5A8 ATP2A2

1.32e-07231235CID000091753
Diseasesarcoma (is_marker_for)

ATRX KDR

1.55e-0451172DOID:1115 (is_marker_for)
DiseaseRecurrent infections

CR2 IL6ST

1.55e-0451172C0239998
Diseaseclubfoot (implicated_via_orthology)

FRAS1 PITX1

2.31e-0461172DOID:11836 (implicated_via_orthology)
Diseasecoronary artery disease

FNDC3B SEMA3C WIPI1 MAP1B LAMC1 TUB SVEP1 ZNF77 GDPD5 SCUBE1 THADA DENND1B NLRP4 ADGRL3

2.77e-04119411714EFO_0001645
Diseasehypothyroidism (biomarker_via_orthology)

PCSK1 MAP1B NCAM1 ATP2A2

2.94e-04801174DOID:1459 (biomarker_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

ARHGAP32 LAMC1 TSC1 CNTNAP5 SHANK2

3.58e-041521175DOID:0060041 (implicated_via_orthology)
Diseasemyocardial infarction

FNDC3B LAMC1 OAS3 ZNF77 THADA ATP2A2 ADGRL3

5.06e-043501177EFO_0000612
Diseasenon-syndromic X-linked intellectual disability (implicated_via_orthology)

FTSJ1 THADA

5.51e-0491172DOID:0050776 (implicated_via_orthology)
Diseasecerebral palsy (implicated_via_orthology)

AGAP7P AGAP4

6.87e-04101172DOID:1969 (implicated_via_orthology)
Diseaseglucose measurement

PCSK1 MAPK8IP1 PDE3B WIPI1 RFX1 THADA SLC35D3

8.20e-043801177EFO_0004468
DiseaseAnkylosing spondylitis

ANTXR2 IL1R2

8.38e-04111172C0038013
Diseaseserum ST2 measurement

IL18RAP DENND1B

8.38e-04111172EFO_0005416
DiseaseMyopia

FRAS1 ANKS1B FRMD4B SLC35D1 CNTNAP5 ANTXR2 FCRL5

8.85e-043851177HP_0000545
DiseaseSecondary Open Angle Glaucoma

FNDC3B MYOC

1.00e-03121172C0271148
DiseaseGlaucoma, Open-Angle

FNDC3B MYOC

1.00e-03121172C0017612
Diseaseresponse to fenofibrate

PCSK5 SCUBE1 SHANK2

1.04e-03501173GO_1901557
DiseaseGlaucoma, Primary Open Angle

FNDC3B MYOC

1.18e-03131172C0339573
Diseasesugar consumption measurement

WIPI1 MYOC FSTL4 NBAS

1.35e-031201174EFO_0010158
Diseaseamyotrophic lateral sclerosis, age at onset

PCSK5 ANKS1B

1.58e-03151172EFO_0004847, MONDO_0004976
Diseaseobesity (implicated_via_orthology)

PCSK1 TSC1 TUB THADA SDK1

1.70e-032151175DOID:9970 (implicated_via_orthology)
DiseaseCannabis use

NCAM1 SDK1

1.80e-03161172EFO_0007585
Diseaserhinitis

IL18RAP EMSY

2.04e-03171172EFO_0008521
DiseaseFamilial Progressive Myoclonic Epilepsy

TSC1 SACS

2.04e-03171172C0751777
DiseaseAtypical Inclusion-Body Disease

TSC1 SACS

2.04e-03171172C0751776
DiseaseMyoclonic Epilepsies, Progressive

TSC1 SACS

2.04e-03171172C0751778
DiseaseBiotin-Responsive Encephalopathy

TSC1 SACS

2.04e-03171172C0751780
DiseaseMay-White Syndrome

TSC1 SACS

2.04e-03171172C0751782
DiseaseDentatorubral-Pallidoluysian Atrophy

TSC1 SACS

2.04e-03171172C0751781
Diseaseglucuronate measurement

FNDC3B IL1R2

2.29e-03181172EFO_0010486
DiseaseAction Myoclonus-Renal Failure Syndrome

TSC1 SACS

2.29e-03181172C0751779
Diseaseobstructive sleep apnea

PCSK1 GAPVD1 THADA

2.32e-03661173EFO_0003918
Diseasebipolar I disorder

MAPK8IP1 ANKS1B SHANK2 ATP2A2

2.44e-031411174EFO_0009963
Diseasecortical surface area change measurement, age at assessment

VIT PCSK6

2.55e-03191172EFO_0008007, EFO_0021503
Diseasepentachlorophenol measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022071
Diseaseparathion measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022070
Diseasepotassium chromate measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022072
Diseasemercuric chloride measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022068
Diseaseheptachlor epoxide measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022067
Diseasemethoxychlor measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022069
Disease4,6-dinitro-o-cresol measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022053
Disease2,4,5-trichlorophenol measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022052
Diseaseazinphos methyl measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022055
Diseasealdrin measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022054
Diseasedicofol measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022060
Diseasedisulfoton measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022062
Diseasedieldrin measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022061
Diseaseendrin measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022064
Diseaseendosulfan measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022063
Diseaseheptachlor measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022066
Diseaseethion measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022065
Diseasechlorpyrifos measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022057
Diseasecadmium chloride measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022056
Diseasediazinon measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022059
Diseasedibutyl phthalate measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0022058
Diseaseenvironmental exposure measurement

NTNG1 CNTNAP5 USH2A

3.09e-03731173EFO_0008360
DiseaseST2 protein measurement

IL18RAP IL1R2

3.12e-03211172EFO_0010599
Diseaseelectroencephalogram measurement

FNDC3B FRMD4B NELL2

3.21e-03741173EFO_0004357
DiseaseDDT metabolite measurement

NTNG1 CNTNAP5 USH2A

3.21e-03741173EFO_0007886
Diseasediffuse plaque measurement

PCSK5 SEMA3C FSTL4 ANKS1B DAPK1 FRMD4B SHANK2 KDR GPA33

3.27e-037581179EFO_0010699
Diseaseresponse to alcohol

PCSK1 UNC93A SHANK2

3.33e-03751173EFO_0005526
Diseasenucleus accumbens volume

GMNC USH2A

3.42e-03221172EFO_0006931
DiseasePR interval

FNDC3B LAMC1 NHLRC2 FRMD4B CNTN6 MPPED2 ADGRL3

3.65e-034951177EFO_0004462
Diseasechronic widespread pain

WDR70 AGAP7P

3.73e-03231172EFO_0010099
DiseaseDepression, Bipolar

NTNG1 NCAM1 SHANK2

3.86e-03791173C0005587

Protein segments in the cluster

PeptideGeneStartEntry
YVTLCSNGVLTYYSS

AGAP4

281

Q96P64
TTTQASYAAQSAYGT

EWSR1

106

Q01844
YASSCNSGTSYNSIS

DAPK1

1411

P53355
SASCTYEGENTVLYL

ACOX2

431

Q99424
TYTCQAITEVNVYGS

CD7

111

P09564
SVGTSYSVYDSSAVQ

CFAP77

71

Q6ZQR2
SLFLDSYTEYCTSIT

ALS2

776

Q96Q42
SYSIASGEYLSNCVQ

ADGRL3

1206

Q9HAR2
GSVLCTYTVNETYTT

ANTXR2

251

P58335
YASQSSSEGSTQTYA

ADAM32

731

Q8TC27
CETTLANVGYTATYD

DIPK1B

296

Q5VUD6
STSTGTILNCYTCAY

ACRV1

181

P26436
STYSDTSAQPTCDYG

AKAP8L

16

Q9ULX6
SSTSSYSGYEGCAVL

RUBCNL

266

Q9H714
YQSTSETVSITYGTG

PGA5

126

P0DJD9
TQTSADAIYDCSSLY

ANGPTL7

121

O43827
EYFEINTSTGCTSFT

ANKS1B

546

Q7Z6G8
LAYCTGSVASYELTQ

IGLV3-1

11

P01715
TDGYTTYINASTCTV

MPPED2

261

Q15777
QGTYVCDYTQSDTVS

IL18RAP

216

O95256
GDLSYESSVRCYTQS

FRAS1

2941

Q86XX4
TTRTPDTSTYCYETA

MAP1B

2031

P46821
TPQASTYSYETSDLC

MAP1B

2051

P46821
RNTVYSSSGVCVLYE

NELL2

346

Q99435
TYSSLLRYTCGSSVE

NLRC4

486

Q9NPP4
ISTDTSGYYICTSSN

GPA33

201

Q99795
TVYDNCASVSSPYES

MAPK8IP1

411

Q9UQF2
SATGLTADCSYQSYF

FNDC7

611

Q5VTL7
DIDAYTTCLYASGTT

SMPDL3B

421

Q92485
TVQYISSFYASCLSG

GAPVD1

1441

Q14C86
SPGRVYEYTSCTTFS

FBXO3

356

Q9UK99
CSCDGYTNSIYTISI

PCSK5

321

Q92824
CSSTLATTYSSGESY

PCSK5

351

Q92824
SCDGYTNSIYTISVS

PCSK6

356

P29122
YLEECASTLATTYSS

PCSK6

381

P29122
ISFSLTTENSGNYYC

FCRL5

341

Q96RD9
SVTLTCTLSSGYSNY

IGLV9-49

36

A0A0B4J1Y8
SCVSLGETAASYYGS

PDE3B

296

Q13370
IICGTLYTVSSYTSA

MYOC

431

Q99972
FSCTDGYVLVYSTDS

NKIRAS2

76

Q9NYR9
ASTYSIDSVSFSYNT

LAMP2

106

P13473
CSDNSYDTYANSTAT

GDPD5

571

Q8WTR4
LALTCQSTTSVYSSF

NLRP4

361

Q96MN2
EYVSSLSSSVRNTCY

ARHGAP32

1556

A7KAX9
LSSVTAADTAVYYCA

IGHV4-59

101

P01825
SYDCTLLAYAESTGT

NBAS

141

A2RRP1
SVSVFLYYCSADSSA

NHLRC2

681

Q8NBF2
YQSTSETVSITYGTG

PGA3

126

P0DJD8
TGTLSQSYQYEVCLT

PCDHB4

741

Q9Y5E5
SYVFSVSYCSSNIIN

OR8J1

161

Q8NGP2
CTQSYSVDSNLLSDY

OSGIN2

361

Q9Y236
SYTSQSSTEYYCVTP

FRMD4B

731

Q9Y2L6
TCSLNEFTITGSTYA

ATP2A2

376

P16615
LDDSCSGSVTYSYSA

ATRX

331

P46100
RDTPTSCTVDYSTVY

IL6ST

176

P40189
SLANVSYGSIVTYTC

CR2

291

P20023
SSIYKSSCTTVYNGY

FNDC3B

211

Q53EP0
NASSEYSGTYSCTVR

CXADR

201

P78310
SSVRYEDTGAYTCIA

FSTL4

401

Q6MZW2
VTLLTGTYYECAASE

CALHM4

121

Q5JW98
SDCLVNTSQISYTIY

HTR1D

186

P28221
NTSQISYTIYSTCGA

HTR1D

191

P28221
YVTLCSNGVLTYYSS

AGAP7P

281

Q5VUJ5
IYNITRSDAGSYTCI

CNTN6

466

Q9UQ52
TVYDGYSKHASTTSC

LYNX1

71

P0DP58
SSVCTNAVGYSVYSI

LAMC1

501

P11047
AYTTTAINGTDFCTS

SLC44A3

496

Q8N4M1
TGSKEVVCYSYTSTT

EMSY

136

Q7Z589
SADSSYLQVSSGCYK

EML5

1831

Q05BV3
TSSYASQQSKVSGYS

FAM102B

206

Q5T8I3
GEICVSSSATGTAYY

DIP2A

746

Q14689
NEEDYGTCSSSVQYT

DENND1B

471

Q6P3S1
ASPTSITTYETCQTY

SCUBE1

861

Q8IWY4
YTCYAANTEGSLNAS

SDK1

551

Q7Z5N4
VSEVSSTCYNTADIY

SACS

1656

Q9NZJ4
ETVPYSVCVSSDYSI

SGK3

456

Q96BR1
TTFYCNCSDTSYTGA

CNTNAP5

566

Q8WYK1
SYTGATCHNSIYEQS

CNTNAP5

576

Q8WYK1
YQSTSETVSITYGTG

PGA4

126

P0DJD7
SYSNAGEYSTCFTEL

OAS3

916

Q9Y6K5
CTEEYSTGYTTNSKI

NTNG1

206

Q9Y2I2
STVFSYSSALNLCYA

GRIN3B

611

O60391
YSVYRDTCNSSLASL

PITX1

271

P78337
TGSASFYDCYTSQSE

MEIOC

56

A2RUB1
YTNYSFTLTACTSAG

USH2A

3651

O75445
CTYINSAVTTSFVGV

SLC35D3

246

Q5M8T2
SSVVSDASSAVYYCN

SOX17

396

Q9H6I2
YSTVLCSYYNSALTT

SLC35D2

256

Q76EJ3
CSYYNSALTTAVVGA

SLC35D2

261

Q76EJ3
LSTSTKPYDCVTASY

THADA

836

Q6YHU6
TTSSSVFKGSAVCVY

SEMA3C

326

Q99985
PEYGTYSLCSSQSSS

TIFA

161

Q96CG3
QSYNCPYSTTTSESS

GMNC

16

A6NCL1
TASTSYYEAAGTATQ

RFX1

326

P22670
NVTSTEVYGAFTCSI

SIGIRR

86

Q6IA17
FVACAYSGTLSTVSS

SLC5A8

341

Q8N695
TFTLISGQCYVTTYE

SLC25A44

81

Q96H78
YATVLCTQYNSALTT

SLC35D1

271

Q9NTN3
ITYSCRSGYVIQGSS

SVEP1

3086

Q4LDE5
EDSGTYVCTTRNASY

IL1R2

101

P27930
YTVGSYDSFDTSSDC

SHANK2

606

Q9UPX8
SGTTVIYTCEFISAY

ADGRF5

441

Q8IZF2
DSSTSASEAYGKSYC

CCDC136

791

Q96JN2
ASEAYGKSYCTTSNS

CCDC136

796

Q96JN2
QYTDAGEYICTASNT

NCAM1

386

P13591
TSSKTVTLFEQYCSG

VPS50

506

Q96JG6
YSESLLCSNLESATY

TOMM34

216

Q15785
PYADTQNSYGCATST

TSC1

296

Q92574
QNSYGCATSTPYSTS

TSC1

301

Q92574
ASLDCYIYVRTSGSS

ZNF77

41

Q15935
YQVLGSSSKTYTCLA

ZSWIM7

66

Q19AV6
GCVYLYGADTTTATT

PHLPP2

31

Q6ZVD8
DYSSTIGSDKGCSQY

TMPRSS7

236

Q7RTY8
TSCTSSTSSLSNYLY

SLCO4C1

216

Q6ZQN7
TSCVTFSYDGNVLAS

WDR70

381

Q9NW82
SYSSYKTCVSSLCVN

FAM170A

106

A1A519
SCSVVGAISSYYVQR

XYLB

251

O75191
QGFLSSEYTRSYVTC

UNC93A

271

Q86WB7
SEYTRSYVTCTLGIQ

UNC93A

276

Q86WB7
TDVYASYSSVCGAAV

VIT

76

Q6UXI7
AALTLNCTYQSSYST

TRAV18

36

A0A075B6X5
VTCGDLSSYDSDRSY

FTSJ1

236

Q9UET6
DVCDYTSTTYVGVRN

ZNF507

761

Q8TCN5
TLGSAVAYCTYSLTR

SLC29A4

496

Q7RTT9
QYGTTQTLTCTVYAI

KDR

436

P35968
SNVDSSYLESLYQSC

ZC3HAV1

631

Q7Z2W4
CLTSVSEYISSDGSY

ZNF12

146

P17014
GTYCYTSSSLSHILQ

ZMYM1

236

Q5SVZ6
YSESGVYSQESLTSS

TOGARAM1

1021

Q9Y4F4
GTEICNYSYSSNILS

WIPI1

91

Q5MNZ9
AELTCTYSTSVGDSF

VSIG2

41

Q96IQ7
VESYLSSSGSTSYQV

TUB

71

P50607
YSSTTSDCETDGYLS

WNK4

576

Q96J92
VCNEYGTTFSQSTYL

ZNF473

266

Q8WTR7
YCSGVESAISSLDYI

VAV3

281

Q9UKW4
SISQTSVYSEYCSTE

KLRB1

191

Q12918
ISFCSQTTSYVAESS

KIAA1522

106

Q9P206
KCSSTLATSYSSGDY

PCSK1

346

P29120