Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Tyr_kinase_rcpt_ROR	ROR1 ROR2	5.26e-05	2	136	2	IPR016247
Domain	-	HSPG2 COL19A1 NBEAL1 LAMA2 CLSTN2 WDFY3	6.82e-05	95	136	6	2.60.120.200
Pubmed	Functional proteomics mapping of a human signaling pathway.	CALCOCO2 NID2 HSPG2 EGLN2 FLT4 MAN2B1 TUSC3 TWNK SIAH1 PDCD7 TGM2 KMT2D LDB1 RUBCN SMAD6	1.85e-08	591	140	15	15231748
Pubmed	Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.	ZNF444 TRIM73 TRIM74	2.21e-06	7	140	3	26025256
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	NID2 HSPG2 COL7A1 LAMA2	5.52e-06	29	140	4	22613833
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HSPG2 MAN2B1 ESYT1 POLR2A KHNYN KSR2 SHC1 TWNK FBXL19 RHPN1 GAS2L1 KMT2D OSBPL5 WDFY3 SPEN PKN3	1.04e-05	1105	140	16	35748872
Pubmed	ROR1 and ROR2 expression in pancreatic cancer.	ROR1 ROR2	1.61e-05	2	140	2	34763666
Pubmed	Tyrosinase is the modifier of retinoschisis in mice.	RS1 TYR	1.61e-05	2	140	2	20876567
Pubmed	SIAH1 ubiquitination-modified HMGCR inhibits lung cancer progression and promotes drug sensitivity through cholesterol synthesis.	SIAH1 HMGCR	1.61e-05	2	140	2	37062828
Pubmed	Loss of mRor1 enhances the heart and skeletal abnormalities in mRor2-deficient mice: redundant and pleiotropic functions of mRor1 and mRor2 receptor tyrosine kinases.	ROR1 ROR2	1.61e-05	2	140	2	11713269
Pubmed	Targeting p16-induced senescence prevents cigarette smoke-induced emphysema by promoting IGF1/Akt1 signaling in mice.	CDKN2A TYR	1.61e-05	2	140	2	31428695
Pubmed	The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation.	ROR1 ROR2	1.61e-05	2	140	2	34155901
Pubmed	Orphan receptor tyrosine kinases ROR1 and ROR2 in hematological malignancies.	ROR1 ROR2	1.61e-05	2	140	2	22988987
Pubmed	A strategy to study tyrosinase transgenes in mouse melanocytes.	CDKN2A TYR	1.61e-05	2	140	2	15826307
Pubmed	Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression.	ROR1 ROR2	1.61e-05	2	140	2	37430307
Pubmed	Spatio-temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system.	ROR1 ROR2	1.61e-05	2	140	2	10231392
Pubmed	Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells.	CDKN2A POLR2A	1.61e-05	2	140	2	15467727
Pubmed	Role of the Ror family receptors in Wnt5a signaling.	ROR1 ROR2	1.61e-05	2	140	2	38587578
Pubmed	Expression and subcellular localization of Ror tyrosine kinase receptors are developmentally regulated in cultured hippocampal neurons.	ROR1 ROR2	1.61e-05	2	140	2	12898527
Pubmed	Identification of a novel class of mammalian phosphoinositol-specific phospholipase C enzymes.	PLCH2 PLCH1	1.61e-05	2	140	2	15583837
Pubmed	Expression of the receptor tyrosine kinase genes, Ror1 and Ror2, during mouse development.	ROR1 ROR2	1.61e-05	2	140	2	11429290
Pubmed	A novel family of cell surface receptors with tyrosine kinase-like domain.	ROR1 ROR2	1.61e-05	2	140	2	1334494
Pubmed	Loss of collagen VII is associated with reduced transglutaminase 2 abundance and activity.	COL7A1 TGM2	1.61e-05	2	140	2	24732400
Pubmed	Neurite extension in central neurons: a novel role for the receptor tyrosine kinases Ror1 and Ror2.	ROR1 ROR2	1.61e-05	2	140	2	15654020
Pubmed	Evolutionary divergence in the catalytic activity of the CAM-1, ROR1 and ROR2 kinase domains.	ROR1 ROR2	1.61e-05	2	140	2	25029443
Pubmed	Characterization of a cDNA encoding a protein with limited similarity to beta1, 3-N-acetylglucosaminyltransferase.	B3GNTL1 B3GNT2	1.61e-05	2	140	2	15560372
Pubmed	Expression of the Ror1 and Ror2 receptor tyrosine kinase genes during mouse development.	ROR1 ROR2	1.61e-05	2	140	2	11455430
Pubmed	Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion.	ROR1 ROR2	1.61e-05	2	140	2	26515598
Pubmed	β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases.	ROR1 ROR2	1.61e-05	2	140	2	26862065
Pubmed	ROR1 and ROR2 play distinct and opposing roles in endometrial cancer.	ROR1 ROR2	1.61e-05	2	140	2	29395309
Pubmed	Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2.	ROR1 ROR2	1.61e-05	2	140	2	24104062
Pubmed	Mater encodes a maternal protein in mice with a leucine-rich repeat domain homologous to porcine ribonuclease inhibitor.	EGLN2 NLRP5	1.61e-05	2	140	2	10754103
Pubmed	Basement membrane composition in the early mouse embryo day 7.	NID2 HSPG2 LAMA2	2.80e-05	15	140	3	15895400
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ZNF444 B3GNTL1 KIF1A PPFIA2 TUSC3 ROR2 TRPM2 KSR2 POMT1 YEATS2 PTPN13 LDB1 MYH14 OSBPL5 BSCL2 ERMARD SLC2A11 KLHL26	3.17e-05	1489	140	18	28611215
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	USP9X POLR2A PTPN13 SVIL NFKBIL1 SPEN SLC2A11 PKN3	4.20e-05	313	140	8	38270169
Pubmed	Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis.	CDKN2A POLR2A	4.81e-05	3	140	2	21088222
Pubmed	PKCθ-JunB axis via upregulation of VEGFR3 expression mediates hypoxia-induced pathological retinal neovascularization.	FLT4 PRKCQ	4.81e-05	3	140	2	32382040
Pubmed	Ror1-Ror2 complexes modulate synapse formation in hippocampal neurons.	ROR1 ROR2	4.81e-05	3	140	2	19958813
Pubmed	Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation.	ROR1 ROR2	4.81e-05	3	140	2	26690702
Pubmed	Long noncoding RNA LNC473 inhibits the ubiquitination of survivin via association with USP9X and enhances cell proliferation and invasion in hepatocellular carcinoma cells.	LINC00473 USP9X	4.81e-05	3	140	2	29605299
Pubmed	E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells.	CDKN2A POLR2A	4.81e-05	3	140	2	21708927
Pubmed	Role of tyrosine residues and protein interaction domains of SHC adaptor in VEGF receptor 3 signaling.	FLT4 SHC1	4.81e-05	3	140	2	9927207
Pubmed	Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors.	FLT4 SHC1	4.81e-05	3	140	2	7970715
Pubmed	Osteopontin promotes age-related adipose tissue remodeling through senescence-associated macrophage dysfunction.	CDKN2A TYR	4.81e-05	3	140	2	37092554
Pubmed	Mutation at tyrosine residue 1337 abrogates ligand-dependent transforming capacity of the FLT4 receptor.	FLT4 SHC1	4.81e-05	3	140	2	7675451
Pubmed	A serine/arginine-rich nuclear matrix cyclophilin interacts with the C-terminal domain of RNA polymerase II.	POLR2A PPIG	4.81e-05	3	140	2	9153302
Pubmed	Trex1 prevents cell-intrinsic initiation of autoimmunity.	TREX1 IRF3	4.81e-05	3	140	2	18724932
Pubmed	Gene structure variation in segmental duplication block C of human chromosome 7q 11.23 during primate evolution.	TRIM73 TRIM74	4.81e-05	3	140	2	26196062
Pubmed	Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors.	SHC1 GRB7	4.81e-05	3	140	2	8940081
Pubmed	PPAR alpha-activation results in enhanced carnitine biosynthesis and OCTN2-mediated hepatic carnitine accumulation.	SLC22A5 BBOX1	4.81e-05	3	140	2	17692817
Pubmed	Extensive cooperation of immune master regulators IRF3 and NFκB in RNA Pol II recruitment and pause release in human innate antiviral transcription.	POLR2A IRF3	4.81e-05	3	140	2	23994473
Pubmed	Rubicon Modulates Antiviral Type I Interferon (IFN) Signaling by Targeting IFN Regulatory Factor 3 Dimerization.	IRF3 RUBCN	4.81e-05	3	140	2	28468885
Pubmed	Interaction with the phosphotyrosine binding domain/phosphotyrosine interacting domain of SHC is required for the transforming activity of the FLT4/VEGFR3 receptor tyrosine kinase.	FLT4 SHC1	4.81e-05	3	140	2	8662748
Pubmed	Evidence for an interaction between the insulin receptor and Grb7. A role for two of its binding domains, PIR and SH2.	SHC1 GRB7	4.81e-05	3	140	2	10803466
Pubmed	Inactivation of the polycomb group protein Ring1B unveils an antiproliferative role in hematopoietic cell expansion and cooperation with tumorigenesis associated with Ink4a deletion.	CDKN2A POLR2A	4.81e-05	3	140	2	18039844
Pubmed	TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells.	TRIM73 TRIM74	4.81e-05	3	140	2	22872646
Pubmed	Contribution of genetic factors for melanoma susceptibility in sporadic US melanoma patients.	CDKN2A TYR	9.60e-05	4	140	2	19320745
Pubmed	The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress.	EGLN2 POLR2A	9.60e-05	4	140	2	18285459
Pubmed	In vivo imaging of lymphatic vessels in development, wound healing, inflammation, and tumor metastasis.	FLT4 TYR	9.60e-05	4	140	2	22474390
Pubmed	Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates.	ROR1 ROR2	9.60e-05	4	140	2	28885975
Pubmed	K-Ras(V14I) -induced Noonan syndrome predisposes to tumour development in mice.	CDKN2A POLR2A	9.60e-05	4	140	2	27174785
Pubmed	TRIM11 negatively regulates IFNβ production and antiviral activity by targeting TBK1.	IRF3 TRIM11	9.60e-05	4	140	2	23675467
Pubmed	A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors.	CDKN2A POLR2A	9.60e-05	4	140	2	17299132
Pubmed	Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival.	PDGFRL TUSC3	9.60e-05	4	140	2	16270321
Pubmed	KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition.	TYR KMT2D	9.60e-05	4	140	2	36525973
Pubmed	The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family protein Dlxin-1 and regulates its intracellular distribution.	ROR1 ROR2	9.60e-05	4	140	2	12754255
Pubmed	Essential role of Wnt5a-Ror1/Ror2 signaling in metanephric mesenchyme and ureteric bud formation.	ROR1 ROR2	9.60e-05	4	140	2	26840931
Pubmed	Coat color dilution in mice because of inactivation of the melanoma antigen MART-1.	CDKN2A TYR	9.60e-05	4	140	2	21943097
Pubmed	von Hippel-Lindau-dependent patterns of RNA polymerase II hydroxylation in human renal clear cell carcinomas.	EGLN2 POLR2A	9.60e-05	4	140	2	20978146
Pubmed	Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins.	NID2 LAMA2	9.60e-05	4	140	2	10022829
Pubmed	Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma.	CDKN2A KMT2D	9.60e-05	4	140	2	33086062
Pubmed	NBR1 mediates autophagic degradation of IRF3 to negatively regulate type I interferon production.	CALCOCO2 IRF3	9.60e-05	4	140	2	35914352
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	ESYT1 ROR1 KHNYN ROR2 TBC1D22B PTPN13 SVIL	9.97e-05	263	140	7	34702444
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	HSPG2 TSPOAP1 SIAH1 HHATL PPIG	1.20e-04	118	140	5	21078624
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	NID2 HSPG2 COL7A1 LAMA2	1.32e-04	64	140	4	22261194
Pubmed	Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes.	TREX1 IRF3	1.60e-04	5	140	2	23160154
Pubmed	Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism.	TREX1 IRF3	1.60e-04	5	140	2	28069950
Pubmed	Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice.	TRIM73 TRIM74	1.60e-04	5	140	2	20049703
Pubmed	Role of Polycomb RYBP in Maintaining the B-1-to-B-2 B-Cell Lineage Switch in Adult Hematopoiesis.	CDKN2A POLR2A	1.60e-04	5	140	2	26711264
Pubmed	A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice.	TREX1 NFKBIL1	1.60e-04	5	140	2	27233670
Pubmed	Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.	CDKN2A POLR2A	1.60e-04	5	140	2	19421407
Pubmed	Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase.	TRIM73 TRIM74	1.60e-04	5	140	2	18398435
Pubmed	The SH2 domain protein GRB-7 is co-amplified, overexpressed and in a tight complex with HER2 in breast cancer.	SHC1 GRB7	1.60e-04	5	140	2	7907978
Pubmed	USP9X counteracts differential ubiquitination of NPHP5 by MARCH7 and BBS11 to regulate ciliogenesis.	USP9X IQCB1	1.60e-04	5	140	2	28498859
Pubmed	A genome-wide gene-environment interaction analysis for tobacco smoke and lung cancer susceptibility.	NID2 SMAD6	1.60e-04	5	140	2	24658283
Pubmed	Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens.	NID2 HSPG2	1.60e-04	5	140	2	12243745
Pubmed	Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan.	NID2 HSPG2	1.60e-04	5	140	2	11493006
Pubmed	Appropriate crypt formation in the uterus for embryo homing and implantation requires Wnt5a-ROR signaling.	ROR1 ROR2	1.60e-04	5	140	2	25043182
Pubmed	IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication.	TREX1 IRF3	1.60e-04	5	140	2	24154727
Pubmed	A genome-wide study reveals rare CNVs exclusive to extreme phenotypes of Alzheimer disease.	NLRP8 NLRP5	1.60e-04	5	140	2	22166940
Pubmed	OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to regulate antiviral immunity.	CALCOCO2 IRF3	1.60e-04	5	140	2	35100065
Pubmed	Genomic analysis of mouse retinal development.	POLR2A MPEG1 IRF3 SAMD7 FZD6 RHPN1 LDB1 BAZ2A KCNJ14 TMEM59L WDFY3 RASL10B PLCH1	2.24e-04	1006	140	13	15226823
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	NID2 HSPG2 COL7A1 LAMA2 TGM2	2.24e-04	135	140	5	28675934
Pubmed	Ror family receptor tyrosine kinases regulate the maintenance of neural progenitor cells in the developing neocortex.	ROR1 ROR2	2.39e-04	6	140	2	22328498
Pubmed	The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.	NID2 HSPG2	2.39e-04	6	140	2	11956183
Pubmed	NDP52 activates nuclear myosin VI to enhance RNA polymerase II transcription.	CALCOCO2 POLR2A	2.39e-04	6	140	2	29187741
Pubmed	TRIM50 regulates Beclin 1 proautophagic activity.	TRIM73 TRIM74	2.39e-04	6	140	2	29604308
Pubmed	Activation of Epithelial Signal Transducer and Activator of Transcription 1 by Interleukin 28 Controls Mucosal Healing in Mice With Colitis and Is Increased in Mucosa of Patients With Inflammatory Bowel Disease.	IRF3 IFNL2	2.39e-04	6	140	2	28342759
Pubmed	MLL associates specifically with a subset of transcriptionally active target genes.	POLR2A KMT2D	2.39e-04	6	140	2	16199523
Pubmed	Deubiquitylase USP9X maintains centriolar satellite integrity by stabilizing pericentriolar material 1 protein.	USP9X IQCB1	2.39e-04	6	140	2	30584065
Pubmed	Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteins.	NID2 HSPG2	2.39e-04	6	140	2	10544250
Pubmed	TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.	TRIM73 TRIM74	2.39e-04	6	140	2	36178239
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 FLT4 PDGFRL ROR1 ROR2 ADAMTSL3 SIGLEC6	2.23e-05	161	95	7	593
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 WDFY3	9.60e-04	9	95	2	1230
GeneFamily	C2 domain containing protein kinases	PRKCQ PKN3	1.20e-03	10	95	2	835
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	FLT4 ROR1 ROR2	1.21e-03	40	95	3	321
GeneFamily	ATAC complex	YEATS2 KAT14	2.05e-03	13	95	2	1058
GeneFamily	Potassium voltage-gated channel subfamily J	KCNJ14 KCNJ16	3.12e-03	16	95	2	276
GeneFamily	Wiskott-Aldrich Syndrome protein family	WHAMM WASF1	3.12e-03	16	95	2	14
Coexpression	GSE20715_0H_VS_6H_OZONE_LUNG_DN	NID2 HSPG2 EGLN2 DRD4 CP POMT1 RS1 NUS1 SPEN	1.20e-06	200	138	9	M4365
Coexpression	SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP	HMGCR B3GNT2 BYSL AK4	1.58e-05	29	138	4	M1592
Coexpression	SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP	HMGCR B3GNT2 BYSL AK4	2.07e-05	31	138	4	MM677
ToppCell	Frontal_cortex-Endothelial\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	NID2 HSPG2 ESYT1 HCAR1 SHC1 CP FZD6 TGM2 SMAD6	8.76e-09	188	140	9	a43392dbd10fc7dbfb31be39b8af8a7ea121c894
ToppCell	LPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GRB7 CP CLSTN2 VARS2 PTPN13 MYH14 PRKCQ PLCH1	1.12e-07	181	140	8	0513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCell	PND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NID2 FLT4 SHC1 CP FZD6 KCNJ14 AK4	1.19e-06	171	140	7	686f95892c3909973c66c9a27159a070a068f175
ToppCell	PND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NID2 FLT4 SHC1 CP FZD6 KCNJ14 AK4	1.19e-06	171	140	7	f7ba03e7bdb687f93782c936c7b3374cc5b3b77c
ToppCell	PND14-Endothelial-Endothelial_lymphatic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NID2 FLT4 SHC1 CP FZD6 KCNJ14 AK4	1.19e-06	171	140	7	d0ac50071a3854d02113c455fcc940a6ec59bbb9
ToppCell	PND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NID2 FLT4 SHC1 CP FZD6 KCNJ14 AK4	1.19e-06	171	140	7	fbf8e9db00573adcada4b25730e191417b7c9999
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CP CLSTN2 VARS2 PTPN13 MYH14 PRKCQ PLCH1	1.61e-06	179	140	7	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CP CLSTN2 VARS2 PTPN13 MYH14 PRKCQ PLCH1	1.61e-06	179	140	7	7db6b97a1c4c7a163d5da4351ba36ac1785d9d7b
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CP CLSTN2 VARS2 PTPN13 MYH14 PRKCQ PLCH1	1.67e-06	180	140	7	b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCell	LPS_only-Epithelial_alveolar-AT_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CP CLSTN2 VARS2 PTPN13 MYH14 PRKCQ PLCH1	1.87e-06	183	140	7	e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCell	Control-Epithelial_alveolar-AT_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ROR1 CP VARS2 PTPN13 MYH14 PRKCQ PLCH1	1.94e-06	184	140	7	51e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCell	Control-Epithelial_alveolar-AT_2-AT2_Progenitor\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ROR1 CP VARS2 PTPN13 MYH14 PRKCQ PLCH1	2.01e-06	185	140	7	8ca1374501eca01d8468130b74d50abfd4329fbe
ToppCell	Control_saline-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor\|Control_saline / Treatment groups by lineage, cell group, cell type	GRB7 CP CPM VARS2 PTPN13 MYH14 SLC2A11	3.15e-06	198	140	7	030ef63e2fc5b3d601c1a48462d797aa19ee7ff5
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 FLT4 COL19A1 NEK10 ROR2 MMEL1	9.73e-06	155	140	6	8fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NID2 HSPG2 COL7A1 PDGFRL ROR2 HCAR1	1.13e-05	159	140	6	92049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDKN2A KIF1A TSPOAP1 TRPM2 DNAAF3 GPR157	1.39e-05	165	140	6	c39f0479955c4e23921f7a450d3bc251a002200f
ToppCell	Control-Myeloid-MoAM1,_IL1R2\|Control / Condition, Lineage and Cell class	DRD4 PDGFRL TRPM2 LAMA2 MMP25 WASF1	1.49e-05	167	140	6	ab6029ba037b6a499da8758864c44e174cde5587
ToppCell	Control-Myeloid-MoAM1,_IL1R2\|Myeloid / Condition, Lineage and Cell class	DRD4 PDGFRL TRPM2 LAMA2 MMP25 WASF1	1.49e-05	167	140	6	6e5140527437193f441ca96893b9a00d346614f3
ToppCell	Adult-Mesenchymal-chondrocyte-D175\|Adult / Lineage, Cell type, age group and donor	ENTPD7 PDGFRL ROR1 LAMA2 TWNK CLSTN2	1.54e-05	168	140	6	14071b961c9bdb54a8259b12a88237b802cbde36
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9\|TCGA-Bladder / Sample_Type by Project: Shred V9	ENTPD7 CP FZD6 PTPN13 GPR157 SPEN	1.70e-05	171	140	6	adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 GRB7 CP RHPN1 KCNJ14 PRKCQ	1.94e-05	175	140	6	f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ENTPD7 TREX1 NBEAL1 MMP25 GPR157 PKN3	2.07e-05	177	140	6	d34b086a5931d7f1737a504952d51c47693e91a8
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LINC00473 ROR2 KSR2 ADAMTSL3 PTPN13 TRPM5	2.34e-05	181	140	6	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLT4 CP FZD6 TGM2 PRKCQ PSPN	2.42e-05	182	140	6	d22ab50b135482915687c70e6dad29bfe2bb2c68
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LINC00473 ROR2 KSR2 ADAMTSL3 PTPN13 TRPM5	2.42e-05	182	140	6	f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCell	Control-Epithelial_alveolar-AT_2-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CP VARS2 PTPN13 MYH14 PRKCQ PLCH1	2.42e-05	182	140	6	e97681a4102f3095d5d9e90ad70f1dc46e90983a
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CP VARS2 PTPN13 MYH14 PRKCQ PLCH1	2.42e-05	182	140	6	17ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCell	Cerebellum-Macroglia\|Cerebellum / BrainAtlas - Mouse McCarroll V32	TMBIM1 HHATL SLC22A5 KCNJ16 PRKCQ BBOX1	2.57e-05	184	140	6	91b047a01d2cad231308279ca37fa699630f7864
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ROR1 CP PTPN13 MYH14 PRKCQ PLCH1	2.65e-05	185	140	6	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CP VARS2 PTPN13 MYH14 PRKCQ PLCH1	2.65e-05	185	140	6	fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CP VARS2 PTPN13 MYH14 PRKCQ PLCH1	2.65e-05	185	140	6	929b68b05b7686341329ac756d7df172cb4b810b
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLT4 CP TBC1D22B TGM2 PRKCQ PKN3	2.65e-05	185	140	6	59acaf025353405948dc34ccccf37ec5c08ea903
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ROR1 GRB7 CP PTPN13 MYH14 PRKCQ	2.73e-05	186	140	6	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	Thalamus-Endothelial\|Thalamus / BrainAtlas - Mouse McCarroll V32	NID2 HSPG2 ESYT1 HCAR1 CP TGM2	2.73e-05	186	140	6	dcc6e4417c4123d5ca6b96fa8ca4874626aaebdb
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CP VARS2 PTPN13 MYH14 PRKCQ PLCH1	2.73e-05	186	140	6	e83718fabb057100835d3357df407f283d23fe16
ToppCell	Ciliated_cells-B-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	NEK10 AKAP14 CP DNAAF3 KCNJ16 GRIN3B	2.81e-05	187	140	6	2b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ROR1 GRB7 CP PTPN13 MYH14 PRKCQ	2.81e-05	187	140	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ROR1 GRB7 CP PTPN13 MYH14 PRKCQ	2.90e-05	188	140	6	43a0508d2524a5b310e89e9422843dcaab999bc3
ToppCell	facs-Heart-LV-3m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VARS2 MSTO1 HHATL YEATS2 PTPN13 IQCB1	2.90e-05	188	140	6	40ce7125fca6f6b6b5cc1637c87d43c29b08f4f1
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CP CLSTN2 PTPN13 MYH14 PRKCQ PLCH1	2.90e-05	188	140	6	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	facs-Heart-LV-3m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VARS2 MSTO1 HHATL YEATS2 PTPN13 IQCB1	2.90e-05	188	140	6	ba7f7ce034c0f42742bf2461f68f8d343ee593a5
ToppCell	Globus_pallidus-Endothelial\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	HSPG2 ESYT1 HCAR1 CP FZD6 TGM2	2.99e-05	189	140	6	ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIA2 ROR1 ROR2 LAMA2 ADAMTSL3 SVIL	3.08e-05	190	140	6	562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCell	facs-GAT-Fat-3m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN2B1 PDGFRL USP9X TGM2 SVIL DYNC1I2	3.08e-05	190	140	6	1d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIA2 ROR1 ROR2 LAMA2 ADAMTSL3 SVIL	3.08e-05	190	140	6	f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	NBEAL1 ROR1 CPM FZD6 PTPN13 MYH14	3.17e-05	191	140	6	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	Hippocampus-Endothelial\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ESYT1 HCAR1 SHC1 CP FZD6 TGM2	3.26e-05	192	140	6	36deadab892d3e639a71f33697bb2d3cbbaa5372
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NID2 PDGFRL ROR2 LAMA2 CLSTN2 ADAMTSL3	3.26e-05	192	140	6	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL7A1 CPM MYH14 SVIL PRKCQ BBOX1	3.56e-05	195	140	6	938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell	Cerebellum-Endothelial\|Cerebellum / BrainAtlas - Mouse McCarroll V32	HSPG2 ESYT1 HCAR1 CASP6 CP TGM2	3.56e-05	195	140	6	2192fd9b4682054776f0716933aed5a4a9412657
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL7A1 CPM MYH14 SVIL PRKCQ BBOX1	3.56e-05	195	140	6	d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID2 HSPG2 PDGFRL ROR1 LAMA2 CP	3.66e-05	196	140	6	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 HSPG2 FLT4 MMP25 TGM2 SVIL	3.66e-05	196	140	6	ed818de15f84f7f28bd06fd69d7876710da232a0
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID2 HSPG2 PDGFRL ROR1 LAMA2 CP	3.66e-05	196	140	6	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LINC00473 PPFIA2 HCAR1 CLSTN2 TGM2 AK4	3.76e-05	197	140	6	3332b9b5bf78f0203ebbd94257a36e9054d896c3
ToppCell	Control_saline-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	GRB7 CP CPM VARS2 PTPN13 MYH14	3.76e-05	197	140	6	44a59dfb889577b3160a5b13ada1276771a00241
ToppCell	Control_saline-Epithelial_alveolar-AT_2\|Control_saline / Treatment groups by lineage, cell group, cell type	GRB7 CP CPM VARS2 PTPN13 MYH14	3.76e-05	197	140	6	b8f62fcd6eb8f47b3cc41f616126f82c68a36e87
ToppCell	Control_saline-Epithelial_alveolar-AT_2-AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	CP CPM VARS2 PTPN13 MYH14 SLC2A11	3.76e-05	197	140	6	f870a26f322668781e3d2832c5d9ef2c7c91011f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 HSPG2 FLT4 TUSC3 MMP25 SMIM43	3.87e-05	198	140	6	72e8b9cccb7b0a2ea9d415218fff4fa2f09728f4
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	NID2 NBEAL1 ROR1 GRB7 CPM MYH14	3.87e-05	198	140	6	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 TUSC3 FZD6 TGM2 PKN3 SMAD6	3.87e-05	198	140	6	8a55589b9244283e4b0b423a4a6d6202e8e0fec9
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NID2 HSPG2 NBEAL1 ROR1 CP MYH14	3.87e-05	198	140	6	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	368C-Endothelial_cells\|368C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 FLT4 TUSC3 TGM2 PKN3 SMAD6	3.87e-05	198	140	6	9a2c2201baee51581733e183065298a97eba4553
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GANC ROR1 CPM PTPN13 MYH14 PLCH1	3.98e-05	199	140	6	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 HSPG2 FLT4 TUSC3 MMP25 SMIM43	3.98e-05	199	140	6	9c40b3ee39860e9d8edafd007daec11abdd95435
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Mesothelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	LINC00473 NID2 PDGFRL ROR2 BRINP2 AK4	3.98e-05	199	140	6	ca970114b5aef4518ce580897a62ac88688b2671
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 HSPG2 FLT4 TUSC3 MMP25 SMIM43	3.98e-05	199	140	6	72b34bce8157abe389e95cd3ed8ba578dce0cbf6
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PGS1 VARS2 TTL RHBDD3 TRIM74 SMAD6	3.98e-05	199	140	6	079931e7196719f22a89cfad82f452ec67219ee5
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HSPG2 FZD6 TGM2 KCND1 PKN3 SMAD6	3.98e-05	199	140	6	6a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	GRB7 CP VARS2 PTPN13 P4HA1 PRKCQ	4.10e-05	200	140	6	e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	GRB7 CP VARS2 PTPN13 MYH14 SLC2A11	4.10e-05	200	140	6	c89f3cb36bb14c476d6a392bfd3ded1c8feecfeb
ToppCell	Biopsy_Other_PF-Epithelial-KRT5-/KRT17+\|Biopsy_Other_PF / Sample group, Lineage and Cell type	CDKN2A COL7A1 KIF1A GRB7 MYH14 TMEM59L	4.10e-05	200	140	6	077e6b9340686de9d0f11b035a8954e1f6a1b790
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NID2 NBEAL1 ROR1 GRB7 CP MYH14	4.10e-05	200	140	6	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CP PTPN13 TRPM5 MYH14 NLRP5	5.09e-05	127	140	5	5b0adbcafad31a6759c9bdce2f7f9591a8edc450
ToppCell	Control-Lymphocytic_NKT-T_cells-iNKT-MAIT\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DRD4 MMP25 TBC1D10C PRKCQ KLHL26	1.15e-04	151	140	5	7e5e35ce601ca3d3722063566e89664909171b8d
ToppCell	Adult-Epithelial-basal_cell-D122\|Adult / Lineage, Cell type, age group and donor	COL7A1 CP KHDC1 PLCH2 TMEM59L	1.27e-04	154	140	5	38d346402417960044ae999e61f0092b46f2b591
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN2A TRPM2 MPEG1 P4HA1 KCNJ16	1.34e-04	156	140	5	d72c2f5f72d269e29033f8728d924e0d4c8772c7
ToppCell	Bronchial_Brush-Epithelial-Goblet_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	GRB7 SIAH1 CPM ADAMTSL3 GPR157	1.47e-04	159	140	5	a8fa49dc2e6ad726d1f4f2b30693fecd1151a485
ToppCell	Bronchial_Brush-Epithelial-Goblet_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	GRB7 SIAH1 CPM ADAMTSL3 GPR157	1.47e-04	159	140	5	95834b767cfb4fb8c5aeea89c10f3e14a1fd15c1
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEK10 TUSC3 CHST6 GRIN3B PLCH1	1.47e-04	159	140	5	5543f5aec6352a7c5923e55daf3ed40ff5cc0f0c
ToppCell	Basal_cells-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	COL7A1 COL19A1 CP KHDC1 RASL10B	1.51e-04	160	140	5	b223cc47e68a29df4758c5ccf8f6dbffe2a6fa1d
ToppCell	368C-Fibroblasts-Fibroblast-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	PDGFRL LAMA2 HHATL TMEM59L PLCH1	1.60e-04	162	140	5	e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell	368C-Fibroblasts-Fibroblast-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	PDGFRL LAMA2 HHATL TMEM59L PLCH1	1.60e-04	162	140	5	ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCell	Basal_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	HCAR1 WHAMM CP ADAMTSL3 KHDC1	1.70e-04	164	140	5	b15a26130a1ea1b370b6e3be21f02a0d6aaf6b3c
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	ENTPD7 COL7A1 PPFIA2 CHST6 TMEM59L	1.70e-04	164	140	5	9b4a6007abae992db871d9f6f731d5af724de30d
ToppCell	droplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN2A KIF1A TSPOAP1 DNAAF3 GPR157	1.70e-04	164	140	5	78de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCell	Control-Epithelial_cells-Airway_basal\|Control / group, cell type (main and fine annotations)	COL7A1 COL19A1 CP KHDC1 PLCH2	2.06e-04	171	140	5	3965ced4be6db14265a90673502fceee425837ca
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HSPG2 CHST6 BRINP2 PKN3 SMAD6	2.06e-04	171	140	5	1597459c971d6befa991d59dc66b41b6a522f797
ToppCell	ASK440-Epithelial-Transformed_epithelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	NID2 COL7A1 LAMA2 NFKBIL1 RHBDD3	2.12e-04	172	140	5	df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NID2 LAMA2 CLSTN2 ADAMTSL3 GRIN3B	2.18e-04	173	140	5	f9d6e892d66f9b94e4d5beb9f5dec9b606bc868a
ToppCell	droplet-Heart-HEART-1m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 GRB7 TBC1D22B FZD6 PRKCQ	2.18e-04	173	140	5	9dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NID2 LAMA2 CLSTN2 ADAMTSL3 GRIN3B	2.18e-04	173	140	5	cbd65dd5b01cc959e3ccbc89330ddd0122296ea3
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	HSPG2 FZD6 TGM2 PKN3 SMAD6	2.18e-04	173	140	5	3a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCell	Adult-Epithelial-basal_cell-D231\|Adult / Lineage, Cell type, age group and donor	COL7A1 TUSC3 WDR87 PLCH2 TMEM59L	2.23e-04	174	140	5	a4f98afe7d1cc2617f6f7bc8092c41df57474b30
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 GANC CP RHPN1 PRKCQ	2.29e-04	175	140	5	9d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EGLN2 FLT4 SHC1 TRIM11 PSPN	2.29e-04	175	140	5	43be63976da5ad0764d24d90919a77ce46068f52
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 GANC CP RHPN1 PRKCQ	2.29e-04	175	140	5	f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCell	droplet-Liver-Npc-18m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN2A MAN2B1 TRPM2 MPEG1 KCNJ16	2.29e-04	175	140	5	1973fff0d7e1a94b31f461a39b91cc7984ebd8f1
ToppCell	droplet-Liver-Npc-18m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN2A MAN2B1 TRPM2 MPEG1 KCNJ16	2.29e-04	175	140	5	92a4a3fd323ee8360edd659f9e16dfddc8788e2f
ToppCell	COVID-19_Mild-Neu_3\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	NBEAL1 FBXL19 KMT2D RHBDD3 SLX4	2.36e-04	176	140	5	2049767fd591045cfcf5b1071d80798e52843f27
Disease	retinoschisis (is_implicated_in)	RS1 TYR	2.02e-05	2	133	2	DOID:8465 (is_implicated_in)
Disease	autosomal recessive limb-girdle muscular dystrophy (is_implicated_in)	LAMA2 HMGCR	2.00e-04	5	133	2	DOID:0110274 (is_implicated_in)
Disease	hereditary spastic paraplegia (is_implicated_in)	KIF1A BSCL2	4.17e-04	7	133	2	DOID:2476 (is_implicated_in)
Disease	n-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 measurement	B3GNTL1 B3GNT2	7.11e-04	9	133	2	EFO_0801817
Disease	Adenocarcinoma of large intestine	PDGFRL ROR1 ROR2 PRKCQ	9.51e-04	96	133	4	C1319315
Disease	Rheumatoid Arthritis	CP MMEL1 B3GNT2 NFKBIL1 PRKCQ	1.18e-03	174	133	5	C0003873
Disease	Congenital muscular dystrophy	LAMA2 POMT1	1.29e-03	12	133	2	cv:C0699743
Disease	skin melanoma (is_implicated_in)	CDKN2A TYR	1.77e-03	14	133	2	DOID:8923 (is_implicated_in)
Disease	glycodeoxycholate measurement	COL7A1 SVIL	1.77e-03	14	133	2	EFO_0010493
Disease	Metastatic melanoma	FLT4 NEK10 ROR1	1.88e-03	54	133	3	C0278883
Disease	Diffuse Large B-Cell Lymphoma	CDKN2A KMT2D SPEN	1.98e-03	55	133	3	C0079744
Disease	head and neck squamous cell carcinoma (is_implicated_in)	CDKN2A PTPN13	2.04e-03	15	133	2	DOID:5520 (is_implicated_in)
Disease	muscular dystrophy (is_implicated_in)	LAMA2 POMT1	2.62e-03	17	133	2	DOID:9884 (is_implicated_in)
Disease	cerebral microbleeds	HSPG2 OSBPL5	3.28e-03	19	133	2	EFO_0010059
Disease	cardiomyopathy (is_implicated_in)	POMT1 SLC22A5	3.28e-03	19	133	2	DOID:0050700 (is_implicated_in)
Disease	anorectal malformation	TRPM2 NLRP8	3.28e-03	19	133	2	MONDO_0019938
Disease	Malignant neoplasm of breast	CDKN2A NID2 COL7A1 COL19A1 ROR1 LAMA2 GRB7 TGM2 KMT2D RASL10B SPEN NLRP8	3.45e-03	1074	133	12	C0006142
Disease	diaphragmatic hernia	TMEM59L KLHL26	4.00e-03	21	133	2	EFO_0008561
Disease	Granulomatous Slack Skin	CDKN2A PRKCQ	4.39e-03	22	133	2	C0376407

Protein segments in the cluster

Peptide	Gene	Start	Entry
RLQRVEVTWRGSHPE	TMEM59L	201	Q9UK28
ALVHRPGMVRFRENW	AKAP14	161	Q86UN6
SFRSHVVREDLNPRW	ESYT1	686	Q9BSJ8
VRAREGVWIPVSLHR	ERVK13-1	251	Q9NX77
EVRLPLQHGWRREVR	BAZ2A	551	Q9UIF9
RVFVVHIPRLTGEWA	CDKN2A	21	Q8N726
WILRAPRRHSEDIAA	C13orf42	201	A0A1B0GVH6
WLESLRIAFQQHRRP	BTBD11	826	A6QL63
LERRNHQPIVEGLRW	ARL13A	171	Q5H913
IEPRITLRGTDHFWR	CLSTN2	631	Q9H4D0
RAAWLRVFQHLGPRE	FBXL19	426	Q6PCT2
DPYRNWRHRISGRIL	NBEAL1	161	Q6ZS30
FKWPHSQIREIHLRR	NBEAL1	1931	Q6ZS30
EFWRRPDGQPATREH	HSPG2	1466	P98160
EPLALGRWHRVSAER	HSPG2	4006	P98160
EGPQWLHVRDFDRLL	TSPOAP1	251	O95153
QTHQWRLGEPIELRR	MPEG1	626	Q2M385
LWRGERRDTANLFPQ	CP	666	P00450
GQLVSPRPARLHRFW	MMP25	346	Q9NPA2
LHRFWEGLPAQVRVV	MMP25	356	Q9NPA2
SSLRQRLWRAFENPH	KCND1	166	Q9NSA2
GDIRQHPLFREINWE	PRKCQ	626	Q04759
VITVRQHRWVFPNRG	DUSP13	156	Q6B8I1
EPVRREGELWHIRAQ	HHATL	236	Q9HCP6
PGEWDDRKVRHTFIR	TMBIM1	86	Q969X1
TWHFSIRQHRELIPR	LDB1	196	Q86U70
IIDFRHWSASLPRDR	ENTPD7	46	Q9NQZ7
WAEVVHLLIERFPGR	NLRP8	81	Q86W28
HLLIERFPGRRAWDV	NLRP8	86	Q86W28
FQRVPRGEILWSHLE	GABPA	231	Q06546
FETLKDRLSRRWIHP	AK4	116	P27144
SREGRPIWQLSHFAR	HMGCR	226	P04035
GRLWRTVIIGEQEHR	ATCAY	151	Q86WG3
LDGFPQLRHWFRIVD	KSR2	86	Q6VAB6
NHERFFWHLTLPERR	CASP6	51	P55212
PALNRVRWTHSGREI	DYNC1I2	571	Q13409
TARRLVWVPSELHGF	MYH14	51	Q7Z406
LPRIFHVNWFRRDEA	PCK2	526	Q16822
LRDRQWLEAVFGTPR	PDCD7	141	Q8N8D1
REWVNRAPSIHFLRV	NEK10	121	Q6ZWH5
KIWQGEPARVRRSHL	PIN1P1	46	O15428
IRVWSDFLRVHLHPR	MSTO1	161	Q9BUK6
GVHRFQWIRNLVPEF	PGS1	76	Q32NB8
ELGRAGIRWEVEPRH	EEF2KMT	296	Q96G04
ISFLFVHPEWRRAGI	KAT14	701	Q9H8E8
RWRADGRSLEKLPVH	NUS1	86	Q96E22
KRREPWLFGEEHTRL	GANC	651	Q8TET4
PRGRRRAVFAAVLHW	DPY19L1	21	Q2PZI1
RRVLRPGGVLFFWEH	METTL7B	161	Q6UX53
ESCWPRHRRVNGTIF	LAMA2	736	P24043
DSDRWGFRPRTVVLH	NLRP5	271	P59047
RWSRFPDLNRILKGH	TWNK	391	Q96RR1
WHPDRFLQRFRSQIE	NFKBIL1	341	Q9UBC1
GGWLRRHVIPETNSR	MMEL1	121	Q495T6
RWEVARRAKLHGRAP	DRD4	221	P21917
WFHGRISREESQRLI	GRB7	431	Q14451
LWGHRFEPVLFQRGS	KCNJ14	326	Q9UNX9
DRFRRSETPPHWRQE	PPIG	351	Q13427
WLHERGQEFRRPCTL	P4HA1	516	P13674
RWRENLLEHYGGTPR	NID2	1021	Q14112
RRRNVHDLPQDAWLR	POMT1	621	Q9Y6A1
EQVQRDIGFWCPRHL	FZD6	151	O60353
PWELFQHRALRRQVT	SLC2A11	261	Q9BYW1
LFRAAVRWLQHDPAR	KLHL26	226	Q53HC5
GAQVIHPQEFRRWRD	DNAAF3	221	Q8N9W5
NLWVLVVGRFPKEHR	CPM	56	P14384
RQAPWREFTGRHRTE	LINC00473	11	A8K010
RELRPLFDRQWHKLG	COL19A1	161	Q14993
LVRRDRDGQHSWVPR	GAS2L1	446	Q99501
HSRLFPRTWDLRQLQ	IFNL2	76	Q8IZJ0
AARGPRTDRLLWAFH	GPR157	111	Q5UAW9
DVITFDNWRLLHGRR	BBOX1	336	O75936
QHFIPRRKDWIGIFR	CALCOCO2	46	Q13137
VRLYPGQRHLELEWS	MAN2B1	701	O00754
FAPWRGLQELTDARR	IQCB1	441	Q15051
IGTVSFHLWIRRNRE	KHDC1	41	Q4VXA5
DRGHRDITVFVPQWR	KHNYN	471	O15037
LRRRHWAFGDIPCRV	HCAR1	76	Q9BXC0
VQRGEHSLRLRWEPV	COL7A1	876	Q02388
LWDFLNHQEGPRIRD	ERMARD	356	Q5T6L9
RLLIFWSDRRNPHEV	EGLN2	346	Q96KS0
GIWPRHRFSLQVNIR	BSCL2	261	Q96G97
RLPEESRREHWQLLG	RUBCN	16	Q92622
SAVIAIREHLGRPWR	SBK2	316	P0C263
IREHLGRPWRQREGE	SBK2	321	P0C263
AWRNHTVPLRLRDGR	SLC22A5	61	O76082
GFRTEKRELPVLWHQ	BYSL	366	Q13895
EPHTSGWARRFVVVR	KIF1A	1586	Q12756
TWRRQFPPREVHGIS	PPFIA2	1196	O75334
EVHNGVRTLVLRFPW	PTPN13	806	Q12923
PLERARELEIGVHWR	PKN3	361	Q6P5Z2
WTPSGEVRRQRLRQH	OSBPL5	621	Q9H0X9
RTRFRIPWKHGLRQD	IRF3	31	Q14653
RHFKVWSLRRDPRGA	GRIN3B	366	O60391
QWIGKHRRPRFVSLR	MRPL57	16	Q9BQC6
DLQRGRVIPRWNVSH	RASL10B	131	Q96S79
LEHWRQPELERRFSR	VARS2	891	Q5ST30
FRLWGEPVNLREQHD	USP9X	1671	Q93008
PALRRASRFAQWAIH	RNF135	246	Q8IUD6
FERILFIWAIRHPAS	TBC1D22B	291	Q9NU19
LGRLFRWPDLQHAVE	SMAD6	226	O43541
GRPDWAIFGRLTEHN	SVIL	1656	O95425
PHFEESWGQRCRRLR	SAMD7	171	Q7Z3H4
GRLSVHREPWGFSRE	SMIM43	46	Q4W5P6
QEETRGRFHLLWDPR	SIGLEC6	86	O43699
ELNGHRRRLTWEATP	SIAH1	226	Q8IUQ4
AEPERHRLRFLVAWN	WHAMM	21	Q8TF30
RPRFKDIHSRLRAWG	ROR2	736	Q01974
RPVTIQDTWRLIHRG	PDGFRL	316	Q15198
NRWRLVGPVHLTRGE	RHPN1	506	Q8TCX5
VRERGLEVSHRLAPW	SLX4	1011	Q8IY92
DWLLTDRGPFHRAQE	BRINP2	56	Q9C0B6
LTPHFARRQAIRESW	B3GNT2	151	Q9NY97
WTHRVRFLEEQALPR	B3GNTL1	246	Q67FW5
RHIPFWTARGVQRAF	APOL5	266	Q9BWW9
QAWRHALPFAKIRRV	CHST6	331	Q9GZX3
GAFRWLEPSERRLQV	RHBDD3	181	Q9Y3P4
RPRFKDIHVRLRSWE	ROR1	736	Q01973
LVVRRGQPFWLTLHF	TGM2	31	P21980
FSWVIRREFQELRHP	TRIM74	171	Q86UV6
WIADRTDVHIRVFRP	TUSC3	181	Q13454
AEGLALDSPWHRFRR	ZNF444	11	Q8N0Y2
FTRQEWHRLDPAQRT	ZNF157	36	P51786
RSGEHWAHRVRPLQD	TRIM11	116	Q96F44
PWAKGDPREFIRVHR	WDFY3	2881	Q8IZQ1
HPHDGRLEWIFRRVL	TRPM5	896	Q9NZQ8
RHLWVGNLPENVREE	SPEN	6	Q96T58
IWRRGHEPQSFIRRN	TSPYL1	356	Q9H0U9
ALVRFLVWDHDPIGR	PLCH2	831	O75038
WMETIGRDLHRQFPL	TBC1D10C	131	Q8IV04
LIHNERRVDWLFRGA	TRPM2	956	O94759
GHRVRILPWSTFRLN	POLR2A	471	P24928
SQWEFPRERLHLGRV	FLT4	836	P35916
PREILWGHRFNDVLE	KCNJ16	301	Q9NPI9
IFEQWLRRHRPLQEV	TYR	396	P14679
VFPSREFWHRLRVIR	MRPL18	71	Q9H0U6
LVRFLVWDHDPIGRD	PLCH1	806	Q4KWH8
FSWVIRREFQELRHP	TRIM73	171	Q86UV7
EKVPRAPHDRRREWQ	WASF1	191	Q92558
SRFIRLIPLGWHVRI	RS1	196	O15537
LRWVDAHARPFGTIR	TREX1	216	Q9NSU2
LLEPGHRKFDIRSWV	TTL	191	Q8NG68
VRIWDFHGRLIGILD	WDR87	591	Q6ZQQ6
DVAFLDDRHRWQRLP	PSPN	131	O60542
EQLRGEPWFHGKLSR	SHC1	481	P29353
HLTRRGWGEFPVRVQ	YEATS2	276	Q9ULM3
ERRWPESRIVFLQGH	ADAMTSL3	1386	P82987
RFPHLGSGRWEQEDR	KMT2D	4721	O14686