Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
PathwaySA_CASPASE_CASCADE

SREBF2 BIRC2

2.04e-0419162M7997
Pubmed

Zinc finger proteins orchestrate active gene silencing during embryonic stem cell differentiation.

ZNF217 ZNF516

2.25e-07217229846698
Pubmed

MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression.

MMP13 BIRC2

6.74e-07317219276372
Pubmed

WNT7B promotes bone formation in part through mTORC1.

MMP13 WNT7B

1.48e-051217224497849
Pubmed

An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation.

ZNF217 ZNF516

1.75e-051317216079794
Pubmed

Coordinated histone modifications mediated by a CtBP co-repressor complex.

ZNF217 ZNF516

2.35e-051517212700765
Pubmed

Noncanonical Wnt signaling through G protein-linked PKCdelta activation promotes bone formation.

MMP13 WNT7B

3.05e-051717217199045
Pubmed

Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.

SREBF2 DIO3

5.66e-052317226508642
Pubmed

Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base.

MMP13 WNT7B

9.70e-053017221911092
Cytoband22q13

SREBF2 WNT7B

4.17e-052617222q13
CytobandEnsembl 112 genes in cytogenetic band chr11q22

MMP13 BIRC2

7.15e-04107172chr11q22
CytobandEnsembl 112 genes in cytogenetic band chr22q13

SREBF2 WNT7B

6.52e-03330172chr22q13
GeneFamilyEndogenous ligands

MMP13 GDF9 WNT7B

7.28e-04237143542
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF217 ZNF516 ZNF563

1.64e-0271814328
ToppCellICU-NoSEP-Lymphocyte-T_NK-NK_CD56bright|ICU-NoSEP / Disease, Lineage and Cell Type

TBC1D16 TSR1 GPR174

3.29e-05167173f4f188a8efca8cdd0ecfb857fe4538c10847eadd
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

WNT7B ALG10B C16orf89

3.65e-05173173ef8d720b99470fe1953661f6e66bc0366266bdb6
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

WNT7B ALG10B C16orf89

3.71e-05174173110369f6b78de34a6d934b5b47cecd023347bc80
ToppCelldistal-Epithelial-Club-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TMPRSS6 WNT7B C16orf89

5.54e-05199173685cefbe6ff5db8b578e50b5849524ac2f347d0c
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-NK_CD56bright|ICU-NoSEP / Disease, condition lineage and cell class

TBC1D16 TSR1 GPR174

5.62e-05200173c2df917900872453ea17a39928e39d071a6d3339
Diseasecervical cancer (is_marker_for)

MMP13 BIRC2

1.95e-0436172DOID:4362 (is_marker_for)
Diseaseurinary bladder cancer (is_marker_for)

MMP13 WNT7B

1.71e-03107172DOID:11054 (is_marker_for)
Diseasecongestive heart failure (biomarker_via_orthology)

MMP13 DIO3

1.71e-03107172DOID:6000 (biomarker_via_orthology)
Diseasebilirubin measurement

UGT2B10 TMPRSS6 ZNF563

1.94e-03442173EFO_0004570
DiseaseMalignant neoplasm of breast

SREBF2 DIO3 BIRC2 TMPRSS6

2.84e-031074174C0006142
DiseaseMammary Neoplasms, Human

SREBF2 DIO3 BIRC2

3.16e-03525173C1257931
DiseaseMammary Carcinoma, Human

SREBF2 DIO3 BIRC2

3.16e-03525173C4704874
DiseaseMammary Neoplasms

SREBF2 DIO3 BIRC2

3.20e-03527173C1458155
DiseaseBreast Carcinoma

SREBF2 DIO3 BIRC2

3.39e-03538173C0678222
Diseaseprostate cancer (is_marker_for)

SREBF2 MMP13

3.59e-03156172DOID:10283 (is_marker_for)
Diseaseobsolete_red blood cell distribution width

UGT2B10 TMPRSS6 ZNF217 ZNF516

6.38e-031347174EFO_0005192
DiseaseNeoplasm Metastasis

SREBF2 DIO3

6.81e-03217172C0027627

Protein segments in the cluster

PeptideGeneStartEntry
CLSHQLLFFLWARMR

C16orf89

196

Q6UX73
KPIFWNLMFFICLFI

ALG10B

391

Q5I7T1
AFMLWLLDFLCIRKH

DIO3

56

P55073
MIFKDRFFWRLHPQQ

MMP13

301

P45452
FLMLWNFKPHARAYR

POC1B

41

Q8TC44
RFWFLMYPFRFHDCK

GPR174

116

Q9BXC1
MARPNKFLLWFCCFA

GDF9

1

O60383
HAKWFPRCEFLIRMK

BIRC2

326

Q13490
MHRNFRKWIFYVFLC

WNT7B

1

P56706
CGRRFKEPWFLKNHM

ZNF516

281

Q92618
NFMLLCPRLKHRWFF

TSR1

121

Q2NL82
QFKHNFLLLFMKLRW

SOGA1

666

O94964
LCHPLGQKFFMERSW

SREBF2

761

Q12772
FCHRWLLLCFKREFP

TBC1D16

606

Q8TBP0
LCGKAFFWPSLLRMH

ZNF563

201

Q8TA94
LMRNSWNFKFPHPFL

UGT2B10

256

P36537
CGRRFKEPWFLKNHM

ZNF217

161

O75362
FFWFILQIPEHRRLM

TMPRSS6

151

Q8IU80