Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K4 monomethyltransferase activity

KMT2C KMT2D SETD1B KMT2A

1.14e-088734GO:0140945
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

KMT2C KMT2D SETD1B KMT2A

3.39e-0810734GO:0140999
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

KMT2C KMT2D SETD1B KMT2A

7.62e-0720734GO:0042800
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

KMT2C KMT2D SETD1B KMT2A

2.00e-0544734GO:0140938
GeneOntologyMolecularFunctionmodification-dependent protein binding

BPTF ATAD2B BRD9 KMT2A CHD8 OTUD7B

1.07e-04206736GO:0140030
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

KMT2C KMT2D SETD1B KMT2A

1.12e-0468734GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

KMT2C KMT2D SETD1B KMT2A

1.19e-0469734GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

KMT2C KMT2D SETD1B KMT2A

1.33e-0471734GO:0042054
GeneOntologyMolecularFunctionlysine-acetylated histone binding

ATAD2B BRD9 KMT2A

1.77e-0430733GO:0070577
GeneOntologyMolecularFunctionacetylation-dependent protein binding

ATAD2B BRD9 KMT2A

1.96e-0431733GO:0140033
GeneOntologyMolecularFunctionhistone binding

BPTF ATAD2B BRD9 KMT2A CHD8 CHD3

4.18e-04265736GO:0042393
GeneOntologyMolecularFunctionprotein methyltransferase activity

KMT2C KMT2D SETD1B KMT2A

5.53e-04103734GO:0008276
GeneOntologyMolecularFunctionN-methyltransferase activity

KMT2C KMT2D SETD1B KMT2A

5.95e-04105734GO:0008170
GeneOntologyMolecularFunctiondelta-catenin binding

PLEKHA7 PTPRT

7.10e-0411732GO:0070097
GeneOntologyMolecularFunctionalpha-catenin binding

PTPRT VCL

8.50e-0412732GO:0045294
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

BPTF CHD8 CHD3 DHX9

1.21e-03127734GO:0008094
GeneOntologyMolecularFunctionhistone modifying activity

KMT2C KMT2D SETD1B KMT2A KDM4B

1.51e-03229735GO:0140993
GeneOntologyMolecularFunctionSUMO binding

PELP1 SOBP

2.17e-0319732GO:0032183
GeneOntologyCellularComponenthistone methyltransferase complex

KMT2C KMT2D SETD1B PELP1 KMT2A CHD8

3.12e-0775766GO:0035097
GeneOntologyCellularComponentmethyltransferase complex

KMT2C KMT2D SETD1B PELP1 KMT2A CHD8

2.69e-06108766GO:0034708
GeneOntologyCellularComponentMLL1 complex

PELP1 KMT2A CHD8

2.12e-0432763GO:0071339
GeneOntologyCellularComponentMLL1/2 complex

PELP1 KMT2A CHD8

2.33e-0433763GO:0044665
GeneOntologyCellularComponentMLL3/4 complex

KMT2C KMT2D

8.41e-0412762GO:0044666
MousePhenoabnormal ectoderm development

BPTF ZBTB17 CHD8 VCL DHX9

4.27e-0655625MP:0001675
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2

2.48e-074753PF14914
DomainLRRC37_N

LRRC37A LRRC37A3 LRRC37A2

2.48e-074753IPR032754
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2

2.48e-074753IPR029423
DomainLRRC37

LRRC37A LRRC37A3 LRRC37A2

2.48e-074753PF15779
DomainLRRC37A/B-like

LRRC37A LRRC37A3 LRRC37A2

2.48e-074753IPR015753
DomainPost-SET_dom

KMT2C KMT2D SETD1B KMT2A

4.21e-0716754IPR003616
DomainPostSET

KMT2C KMT2D SETD1B KMT2A

4.21e-0716754SM00508
DomainPOST_SET

KMT2C KMT2D SETD1B KMT2A

4.21e-0716754PS50868
DomainPHD

BPTF KMT2C KMT2D KMT2A CHD3 KDM4B

5.53e-0775756PF00628
DomainFYrich_C

KMT2C KMT2D KMT2A

6.18e-075753IPR003889
DomainFYrich_N

KMT2C KMT2D KMT2A

6.18e-075753IPR003888
DomainFYRC

KMT2C KMT2D KMT2A

6.18e-075753SM00542
DomainFYRN

KMT2C KMT2D KMT2A

6.18e-075753SM00541
DomainFYRN

KMT2C KMT2D KMT2A

6.18e-075753PF05964
DomainFYRC

KMT2C KMT2D KMT2A

6.18e-075753PF05965
DomainFYRC

KMT2C KMT2D KMT2A

6.18e-075753PS51543
DomainFYRN

KMT2C KMT2D KMT2A

6.18e-075753PS51542
DomainPHD

BPTF KMT2C KMT2D KMT2A CHD3 KDM4B

1.53e-0689756SM00249
DomainEPHD

KMT2C KMT2D KMT2A KDM4B

1.66e-0622754PS51805
DomainZnf_PHD

BPTF KMT2C KMT2D KMT2A CHD3 KDM4B

1.74e-0691756IPR001965
DomainZF_PHD_2

BPTF KMT2C KMT2D KMT2A CHD3 KDM4B

2.24e-0695756PS50016
DomainZF_PHD_1

BPTF KMT2C KMT2D KMT2A CHD3 KDM4B

2.38e-0696756PS01359
DomainZnf_PHD-finger

BPTF KMT2C KMT2D KMT2A CHD3

1.63e-0579755IPR019787
DomainSET

KMT2C KMT2D SETD1B KMT2A

2.17e-0541754PF00856
DomainBROMODOMAIN_2

BPTF ATAD2B BRD9 KMT2A

2.17e-0541754PS50014
DomainBROMO

BPTF ATAD2B BRD9 KMT2A

2.39e-0542754SM00297
DomainBromodomain

BPTF ATAD2B BRD9 KMT2A

2.39e-0542754IPR001487
Domain-

BPTF ATAD2B BRD9 KMT2A

2.39e-05427541.20.920.10
DomainZnf_FYVE_PHD

BPTF KMT2C KMT2D KMT2A CHD3 KDM4B

2.76e-05147756IPR011011
DomainSET

KMT2C KMT2D SETD1B KMT2A

3.44e-0546754SM00317
DomainDUF4592

KIAA1210 CRACDL

4.76e-053752IPR028030
DomainDUF4592

KIAA1210 CRACDL

4.76e-053752PF15262
DomainSET_dom

KMT2C KMT2D SETD1B KMT2A

4.80e-0550754IPR001214
DomainSET

KMT2C KMT2D SETD1B KMT2A

4.80e-0550754PS50280
DomainDNA/RNA_helicase_DEAH_CS

CHD8 CHD3 DHX9

3.71e-0435753IPR002464
DomainBROMODOMAIN_1

BPTF ATAD2B BRD9

4.38e-0437753PS00633
DomainDEAH_ATP_HELICASE

CHD8 CHD3 DHX9

4.74e-0438753PS00690
DomainBromodomain

BPTF ATAD2B BRD9

4.74e-0438753PF00439
DomainAT_hook

KMT2C KMT2A

1.84e-0316752PF02178
DomainC1

KMT2C STAC3 DEF8

2.27e-0365753SM00109
DomainHMG_box_dom

KMT2C KMT2D CHD3

2.27e-0365753IPR009071
DomainPE/DAG-bd

KMT2C STAC3 DEF8

2.37e-0366753IPR002219
Domainfn3

CMYA5 DSCAML1 PTPRT MYBPC1

4.11e-03162754PF00041
DomainChromo_domain

CHD8 CHD3

4.15e-0324752IPR023780
DomainSH3_1

AHI1 STAC3 MAP3K11 TXK

4.29e-03164754PF00018
DomainBromodomain_CS

BPTF ATAD2B

4.86e-0326752IPR018359
DomainChromo

CHD8 CHD3

4.86e-0326752PF00385
DomainAT_hook

KMT2C KMT2A

5.23e-0327752SM00384
DomainAT_hook_DNA-bd_motif

KMT2C KMT2A

5.23e-0327752IPR017956
DomainCHROMO_1

CHD8 CHD3

5.62e-0328752PS00598
DomainCHROMO_2

CHD8 CHD3

5.62e-0328752PS50013
DomainZnF_U1

ZFHX2 ZFHX3

6.02e-0329752SM00451
DomainZnf_U1

ZFHX2 ZFHX3

6.02e-0329752IPR003604
DomainFN3

CMYA5 DSCAML1 PTPRT MYBPC1

6.56e-03185754SM00060
DomainSNF2_N

CHD8 CHD3

7.30e-0332752IPR000330
DomainChromodomain-like

CHD8 CHD3

7.30e-0332752IPR016197
DomainSNF2_N

CHD8 CHD3

7.30e-0332752PF00176
DomainChromo/shadow_dom

CHD8 CHD3

7.75e-0333752IPR000953
DomainCHROMO

CHD8 CHD3

7.75e-0333752SM00298
PathwayREACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES

KMT2C KMT2D SETD1B KMT2A

1.11e-0542474M48018
PathwayWP_HISTONE_MODIFICATIONS

KMT2C KMT2D SETD1B KMT2A

6.33e-0565474M39374
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

KMT2C KMT2D SETD1B KMT2A

8.46e-0570474M27231
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

KMT2C KMT2D SETD1B KMT2A CHD3 KDM4B

2.70e-04272476M29619
PathwayREACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES

KMT2D SETD1B KMT2A

2.70e-0438473MM17073
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

KMT2D SETD1B KMT2A CHD3 KDM4B

2.80e-04175475MM14941
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

KMT2C KMT2D SETD1B KMT2A

2.88e-0496474M27792
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

KMT2D SETD1B KMT2A

4.18e-0444473MM15527
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

KMT2D SETD1B KMT2A

4.77e-0446473MM14933
Pubmed

Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.

KMT2C KMT2D SETD1B KMT2A

1.54e-09877423130995
Pubmed

The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.

KMT2C KMT2D SETD1B KMT2A

1.54e-09877422266653
Pubmed

Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.

KMT2C KMT2D SETD1B KMT2A

2.77e-09977422665483
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

PPP1R10 BPTF KMT2C KMT2D SETD1B SFSWAP KMT2A ACIN1 CHD8

4.84e-0925177931076518
Pubmed

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

KMT2C KMT2D KMT2A

1.04e-08377323932714
Pubmed

Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.

KMT2C KMT2D SETD1B KMT2A

1.08e-081277427563068
Pubmed

A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.

KMT2C KMT2D KMT2A

4.17e-08477323129768
Pubmed

The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.

KMT2C KMT2D KMT2A

4.17e-08477324081332
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A LRRC37A3 LRRC37A2

4.17e-08477322419166
Pubmed

Impact of WIN site inhibitor on the WDR5 interactome.

KMT2C KMT2D KMT2A CHD8 KIF2A

4.20e-084377533472061
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

BPTF KMT2D SETD1B BRD9 CHD8 CHD3 KDM4B

6.16e-0815777730186101
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

PPP1R10 BPTF KMT2C KMT2D PELP1 KMT2A ACIN1 CHD8 CHD3 CCNB1

8.85e-08469771027634302
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KMT2C KMT2D KMT2A KDM4B

1.29e-072177427626377
Pubmed

Structural basis for activity regulation of MLL family methyltransferases.

KMT2C KMT2D SETD1B KMT2A

1.58e-072277426886794
Pubmed

New nomenclature for chromatin-modifying enzymes.

KMT2C KMT2D SETD1B KMT2A KDM4B

1.78e-075777518022353
Pubmed

Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.

PPP1R10 BPTF KMT2C KMT2D SETD1B KMT2A

2.75e-0711977623508102
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

BPTF PELP1 PABPN1 BRD9 KMT2A ACIN1 CHD8 CHD3 LTBP1 KIF2A

2.87e-07533771030554943
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

ANTXR2 PELP1 KMT2A ACIN1 CHD3 DHX9 OTUD7B

3.43e-0720277724639526
Pubmed

Clustered PHD domains in KMT2/MLL proteins are attracted by H3K4me3 and H3 acetylation-rich active promoters and enhancers.

KMT2C KMT2D KMT2A

3.63e-07777336598580
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

PPP1R10 BPTF KMT2C UBE2O KMT2D CAST KMT2A ACIN1 CHD8 VCL

3.77e-07549771038280479
Pubmed

Four enzymes cooperate to displace histone H1 during the first minute of hormonal gene activation.

BPTF KMT2C KMT2D

5.80e-07877321447625
Pubmed

Identification and characterization of a novel human PP1 phosphatase complex.

PPP1R10 KMT2C KMT2D SETD1B

6.68e-073177420516061
Pubmed

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

KMT2D PELP1 KMT2A CHD8

6.68e-073177415960975
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

BPTF ATAD2B BRD9 KMT2A DHX9

7.13e-077577525593309
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

PPP1R10 BPTF KMT2D PEG10 KMT2A ACIN1 CHD8 CHD3

9.20e-0734177832971831
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BPTF KMT2D SFSWAP CAST KMT2A ACIN1 CHD3 ZNF579 KDM4B DHX9 OTUD7B

1.09e-06774771115302935
Pubmed

Interaction network of human early embryonic transcription factors.

BPTF KMT2C KMT2D SOBP BRD9 KMT2A ZFHX3 CHD8

1.14e-0635177838297188
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

PPP1R10 BPTF SFSWAP PELP1 ATAD2B BRD9 CAST KMT2A ACIN1 CHD8 CHD3 DHX9

1.21e-06954771236373674
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A LRRC37A3 LRRC37A2

1.24e-061077323064749
Pubmed

Human transcription factor protein interaction networks.

BPTF KMT2C UBE2O KMT2D PABPN1 SOBP PEG10 BRD9 KMT2A ZFHX3 CHD8 CHD3 SMG5 VCL

2.73e-061429771435140242
Pubmed

Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis.

KMT2C KMT2D KDM4B

2.94e-061377321502505
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

PPP1R10 BPTF ACIN1 ZFHX3 CHD8 CHD3 DHX9

3.24e-0628377730585729
Pubmed

Enzymatic nucleosome acetylation selectively affects activity of histone methyltransferases in vitro.

KMT2C SETD1B KMT2A

4.66e-061577335907431
Pubmed

Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.

KMT2C KMT2D SETD1B KMT2A

4.73e-065077437974198
Pubmed

Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.

KMT2C KMT2D

4.84e-06277228483418
Pubmed

The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.

KMT2C KMT2D

4.84e-06277234156443
Pubmed

KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.

KMT2C KMT2D

4.84e-06277231924266
Pubmed

Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.

KMT2C KMT2D

4.84e-06277227280393
Pubmed

Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.

KMT2C KMT2D

4.84e-06277236869380
Pubmed

Set1 and MLL1/2 Target Distinct Sets of Functionally Different Genomic Loci In Vivo.

KMT2D KMT2A

4.84e-06277226711341
Pubmed

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.

KMT2C KMT2D

4.84e-06277228967912
Pubmed

Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant.

KMT2D KMT2A

4.84e-06277224423662
Pubmed

Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.

KMT2C KMT2D

4.84e-06277225346535
Pubmed

Overexpression of TMEM79 combined with SMG5 is related to prognosis, tumor immune infiltration and drug sensitivity in hepatocellular carcinoma.

TMEM79 SMG5

4.84e-06277237936239
Pubmed

Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.

KMT2C KMT2D

4.84e-06277236601880
Pubmed

Stac3 has a direct role in skeletal muscle-type excitation-contraction coupling that is disrupted by a myopathy-causing mutation.

STAC3 RYR1

4.84e-06277227621462
Pubmed

SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.

KMT2C SETD1B KMT2A

5.72e-061677323870121
Pubmed

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.

KMT2C KMT2D SETD1B

5.72e-061677324368734
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

PPP1R10 BPTF UBE2O ATAD2B BRD9 KMT2A CHD8 CHD3 KDM4B

8.06e-0660877936089195
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

BPTF PELP1 CAST ACIN1 CHD8 CHD3 KIF2A

9.20e-0633277732786267
Pubmed

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.

KMT2C KMT2D SETD1B

1.16e-052077329785026
Pubmed

Bayesian modeling to predict malignant hyperthermia susceptibility and pathogenicity of RYR1, CACNA1S and STAC3 variants.

STAC3 RYR1

1.45e-05377231559918
Pubmed

Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.

KMT2D KMT2A

1.45e-05377226902498
Pubmed

Malignant Hyperthermia Susceptibility

STAC3 RYR1

1.45e-05377220301325
Pubmed

MLL histone methylases regulate expression of HDLR-SR-B1 in presence of estrogen and control plasma cholesterol in vivo.

KMT2D KMT2A

1.45e-05377223192982
Pubmed

STAC3 incorporation into skeletal muscle triads occurs independent of the dihydropyridine receptor.

STAC3 RYR1

1.45e-05377230071129
Pubmed

Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.

KMT2C KMT2D

1.45e-05377222183980
Pubmed

STAC proteins: The missing link in skeletal muscle EC coupling and new regulators of calcium channel function.

STAC3 RYR1

1.45e-05377230543836
Pubmed

The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome.

KMT2D CHD3

1.45e-05377226551667
Pubmed

Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.

KMT2D KMT2A

1.45e-05377230315824
Pubmed

HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.

KMT2C KMT2D

1.45e-05377221683083
Pubmed

Genetic interaction mapping in mammalian cells using CRISPR interference.

KMT2D SETD1B BRD9 KMT2A

1.72e-056977428481362
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

PPP1R10 BPTF KMT2C KMT2D ZBTB17 SFSWAP PELP1 PABPN1 KMT2A ACIN1 CHD3 DHX9

2.63e-051294771230804502
Pubmed

Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.

KMT2C KMT2D

2.89e-05477219221051
Pubmed

Cancer gene mutation frequencies for the U.S. population.

KMT2C KMT2D

2.89e-05477234645806
Pubmed

Carm1 regulates Pax7 transcriptional activity through MLL1/2 recruitment during asymmetric satellite stem cell divisions.

KMT2D KMT2A

2.89e-05477222863532
Pubmed

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.

KMT2C KMT2D

2.89e-05477228398509
Pubmed

Behavioral abnormalities observed in Zfhx2-deficient mice.

ZFHX2 ZFHX3

2.89e-05477223300874
Pubmed

KDM5A noncanonically binds antagonists MLL1/2 to mediate gene regulation and promotes epithelial to mesenchymal transition.

KMT2D KMT2A

2.89e-05477237722486
Pubmed

Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.

KMT2C KMT2A

2.89e-05477219703992
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

SFSWAP PELP1 PABPN1 KMT2A KIF2A VCL DHX9

4.46e-0542577724999758
Pubmed

Evolving Catalytic Properties of the MLL Family SET Domain.

KMT2D KMT2A

4.82e-05577226320581
Pubmed

Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.

SETD1B KMT2A

4.82e-05577225561738
Pubmed

Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.

KMT2C KMT2D

4.82e-05577231127101
Pubmed

MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.

KMT2D KMT2A

4.82e-05577228609655
Pubmed

NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler.

BPTF CHD8

4.82e-05577226626481
Pubmed

MLL3/MLL4-Associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBPβ and C/EBPδ.

KMT2C KMT2D

4.82e-05577232601106
Pubmed

A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex.

KMT2C KMT2D

4.82e-05577226744420
Pubmed

An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.

ACIN1 ZFHX3 CHD3 DHX9

5.13e-059177420362542
Pubmed

CHARGE and Kabuki syndromes: a phenotypic and molecular link.

KMT2D CHD8

7.22e-05677224705355
Pubmed

Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs.

KMT2D KMT2A

7.22e-05677224176642
Pubmed

GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi's Sarcoma-Associated Herpesvirus-Induced Cellular Transformation.

KMT2D KMT2A

7.22e-05677234933446
Pubmed

Skeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractility.

STAC3 RYR1

7.22e-05677223818578
Pubmed

MLL associates specifically with a subset of transcriptionally active target genes.

KMT2D KMT2A

7.22e-05677216199523
Pubmed

Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.

KMT2C KMT2D

7.22e-05677217021013
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

PPP1R10 BPTF ZBTB17 ACIN1 ZFHX3 CHD3 FBLIM1 ZC3H6 KDM4B

7.42e-0580877920412781
Pubmed

A protein interaction landscape of breast cancer.

PPP1R10 BRD9 ACIN1 LTBP1 SMG5 PLEKHA7 CCNB1 DHX9

8.13e-0563477834591612
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

KMT2A ACIN1 ZFHX3 CHD3

8.31e-0510377432744500
Pubmed

Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.

ZFHX3 CHD3 ZNF579

8.32e-053877333283408
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SETD1B PEG10 ZFHX2 SMG5

8.63e-0510477410470851
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

BPTF UBE2O PELP1 ATAD2B KMT2A ACIN1 CHD8 VCL

9.97e-0565377822586326
Pubmed

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.

CHD8 CHD3

1.01e-04777226816381
Pubmed

Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4.

KMT2C KMT2D

1.01e-04777230604749
Pubmed

Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes.

KMT2D KMT2A

1.01e-04777219219072
Pubmed

Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex.

KMT2C KMT2A

1.01e-04777226324722
Pubmed

Histone recognition and large-scale structural analysis of the human bromodomain family.

ATAD2B BRD9

1.01e-04777222464331
Pubmed

ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.

KMT2C KMT2D

1.01e-04777219556342
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

KMT2C FAF2 SPEF2 KMT2A RYR1

1.02e-0420877533230847
Pubmed

Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.

PELP1 KMT2A ACIN1

1.13e-044277335705031
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

BPTF KMT2C UBE2O KMT2D SETD1B KMT2A CHD3

1.16e-0449577727705803
InteractionASH2L interactions

KMT2C KMT2D SETD1B PELP1 KMT2A CHD8 KDM4B MYBPC1

6.34e-06265758int:ASH2L
InteractionDPY30 interactions

BPTF KMT2C KMT2D SETD1B KMT2A CHD3 CCNB1

1.09e-05204757int:DPY30
InteractionRBBP5 interactions

KMT2C KMT2D SETD1B PELP1 KMT2A CHD8 CHD3 KDM4B

1.13e-05287758int:RBBP5
InteractionHCFC1 interactions

KMT2C UBE2O KMT2D SETD1B ZBTB17 PELP1 KMT2A CHD8

1.32e-05293758int:HCFC1
InteractionNUP43 interactions

BPTF KMT2D SETD1B PELP1 ATAD2B KMT2A ACIN1 ZFHX3 CHD8 CHD3 KIF2A

1.89e-056257511int:NUP43
InteractionH3-3A interactions

PPP1R10 BPTF KMT2C KMT2D SETD1B PELP1 ATAD2B BRD9 KMT2A CHD8 CHD3 KDM4B

1.94e-057497512int:H3-3A
InteractionCLIP4 interactions

UBE2O PEG10 CMYA5 MYBPC1

2.80e-0547754int:CLIP4
InteractionPHF20 interactions

KMT2C SETD1B KMT2A CHD8

4.51e-0553754int:PHF20
InteractionWDR5 interactions

KMT2C UBE2O KMT2D SETD1B PELP1 PABPN1 BRD9 KMT2A ACIN1 CHD8 CHD3 KIF2A KDM4B DHX9

4.77e-0511017514int:WDR5
InteractionLGR4 interactions

ANTXR2 PELP1 KMT2A ACIN1 CHD3 DHX9 OTUD7B

5.41e-05262757int:LGR4
InteractionNSD3 interactions

BPTF STAC3 BRD9 CHD8 DHX9

7.55e-05117755int:NSD3
InteractionBRD3 interactions

BPTF SFSWAP PABPN1 BRD9 KMT2A ACIN1 CHD8 LTBP1 KIF2A

8.88e-05494759int:BRD3
InteractionH3C3 interactions

BPTF UBE2O ATAD2B BRD9 KMT2A CHD8 CHD3 FBLIM1 KDM4B

9.02e-05495759int:H3C3
InteractionMEN1 interactions

PPP1R10 BPTF KMT2C KMT2D SETD1B PELP1 PABPN1 PEG10 KMT2A ACIN1 CHD8 CHD3 DHX9

9.86e-0510297513int:MEN1
InteractionUHRF2 interactions

BPTF KMT2A CHD8 CHD3 KDM4B CCNB1

1.01e-04200756int:UHRF2
InteractionEPB41L2 interactions

PPP1R10 BPTF UBE2O BRD9 FAM83G ACIN1 CHD3

1.24e-04299757int:EPB41L2
InteractionKMT2C interactions

KMT2C KMT2D SETD1B KMT2A KDM4B

1.43e-04134755int:KMT2C
InteractionPHF20L1 interactions

KMT2C SETD1B KMT2A CHD3

1.76e-0475754int:PHF20L1
InteractionSETD1B interactions

KMT2C KMT2D SETD1B KMT2A

1.76e-0475754int:SETD1B
InteractionNFIX interactions

BPTF KMT2C KMT2D KMT2A ZFHX3 VCL

2.01e-04227756int:NFIX
InteractionKLF3 interactions

BPTF KMT2D SOBP KMT2A ZFHX3 CHD3

2.06e-04228756int:KLF3
InteractionBOD1L1 interactions

KMT2C UBE2O KMT2D SETD1B KMT2A

2.35e-04149755int:BOD1L1
Cytoband14q11.2

PABPN1 ZFHX2 ACIN1 CHD8

2.47e-0418077414q11.2
Cytoband11q23

KMT2A DSCAML1

1.69e-033677211q23
CytobandEnsembl 112 genes in cytogenetic band chr14q11

PABPN1 ZFHX2 ACIN1 CHD8

2.40e-03332774chr14q11
Cytoband1p31.3

KANK4 DNAI4

3.36e-03517721p31.3
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2C KMT2D SETD1B KMT2A

1.34e-0634444487
GeneFamilyPHD finger proteins

BPTF KMT2C KMT2D KMT2A CHD3

2.55e-069044588
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZFHX2 ZFHX3

5.96e-0415442529
GeneFamilyFibronectin type III domain containing

CMYA5 DSCAML1 PTPRT MYBPC1

6.09e-04160444555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

DSCAML1 MFAP3L MYBPC1

7.03e-03161443593
CoexpressionMONNIER_POSTRADIATION_TUMOR_ESCAPE_UP

PPP1R10 AEBP1 PABPN1 SLC19A1 FAM83G LTBP1 SMG5 DHX9 OTUD7B

3.11e-06408779M11891
CoexpressionMONNIER_POSTRADIATION_TUMOR_ESCAPE_UP

PPP1R10 AEBP1 PABPN1 SLC19A1 FAM83G LTBP1 SMG5 DHX9 OTUD7B

3.58e-06415779MM1028
CoexpressionGSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP

BPTF SOBP BRD9 ZFHX3 CHD8 VCL

2.69e-05199776M7259
CoexpressionSTEARMAN_LUNG_CANCER_EARLY_VS_LATE_UP

ANTXR2 CAST KMT2A CHD8 SLC4A5

3.83e-05128775M4925
CoexpressionSTEARMAN_LUNG_CANCER_EARLY_VS_LATE_UP

ANTXR2 CAST KMT2A CHD8 SLC4A5

4.77e-05134775MM748
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

SPEF2 ZFHX2 SAXO2 DNAI4 KIAA2012 DSCAML1 PTPRT

3.35e-0818577730f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AEBP1 FAM83G LTBP1 PTPRT CCNB1 MYBPC1

6.62e-07178776c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 ANTXR2 AEBP1 LTBP1 FBLIM1 VCL

1.06e-06193776c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 ANTXR2 AEBP1 LTBP1 FBLIM1 VCL

1.06e-061937765b602b1702283184bd3943c2a6f2290b7c37e407
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 ANTXR2 AEBP1 LTBP1 FBLIM1 VCL

1.09e-0619477690efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 ANTXR2 AEBP1 LTBP1 FBLIM1 VCL

1.09e-06194776df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 ANTXR2 AEBP1 LTBP1 FBLIM1 VCL

1.13e-06195776cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 ANTXR2 AEBP1 LTBP1 FBLIM1 VCL

1.13e-06195776783bfa8110161cbd6def50ce849cae676c39c458
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRACDL SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.13e-061957769651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 ANTXR2 AEBP1 LTBP1 FBLIM1 VCL

1.16e-061967763a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 ANTXR2 AEBP1 LTBP1 FBLIM1 VCL

1.16e-06196776bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 ANTXR2 AEBP1 LTBP1 FBLIM1 VCL

1.20e-0619777609946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 ANTXR2 AEBP1 LTBP1 FBLIM1 VCL

1.23e-0619877679576525a10ed3e3a9d1608077cd16ecda23376f
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BPTF KMT2C ATAD2B CAST KMT2A ACIN1

1.31e-0620077612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAG1 BRD9 CHD8 CNGB1 TXK

2.38e-06123775511b7c20a4a85e49980936d52af7dbca19bb848e
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|COVID-19 / Disease (COVID-19 only), tissue and cell type

SCN4A STAC3 GBX1 RYR1 MYBPC1

5.14e-06144775f92e03dd784e31a9e5dbd4f4c3a6517ea19210cf
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KMT2C ZFHX2 ZFHX3 CMYA5 PTPRT

1.09e-051687758072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.12e-0516977514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellPND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UBE2O PEG10 KIF2A MFAP3L OTUD7B

1.29e-05174775a3f4981b10afa9d41a1c66c7f98522a8a534f82b
ToppCellPND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UBE2O PEG10 KIF2A MFAP3L OTUD7B

1.29e-051747756cc108dde4b3f98a78a6040280f0d5e4aaa5bd75
ToppCellPND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UBE2O PEG10 KIF2A MFAP3L OTUD7B

1.29e-051747754b8bc5568e36031c8ecf001bb646809038c23919
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_RORB_CARTPT|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANTXR2 CRACDL CNGB1 MYBPC1 TXK

1.52e-051807755e78b29fa1cbdcf502fee3577e5b45766b90d1dc
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.60e-051827757ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.60e-05182775fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AEBP1 SAXO2 DNAI4 PLEKHA7 KIAA2012

1.69e-05184775264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAG1 ANTXR2 CRACDL CMYA5 TXK

1.69e-051847756475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AEBP1 SAXO2 DNAI4 PLEKHA7 KIAA2012

1.69e-05184775d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AEBP1 SAXO2 DNAI4 PLEKHA7 KIAA2012

1.69e-0518477522010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CRACDL SPEF2 SAXO2 DNAI4 KIAA2012

1.73e-05185775f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.73e-0518577518a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CRACDL SPEF2 SAXO2 DNAI4 PTPRT

1.78e-0518677576033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellCiliated_cells-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.82e-051877756fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.87e-0518877561a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.87e-0518877534b11f72ca73153d02edcd09b38983ad1a504659
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.87e-051887752b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.92e-05189775a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.92e-0518977568a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.92e-05189775dc440015949a768188c67661b6be63b1ead1a0f0
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.92e-05189775b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.92e-0518977527329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

1.92e-051897753e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellCiliated_cells-A|World / lung cells shred on cell class, cell subclass, sample id

CRACDL SPEF2 SAXO2 DNAI4 PTPRT

1.97e-05190775cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAG1 DNAI4 CHD8 KIF2A TXK

2.02e-051917759bb6a6b88f351217455765ba07a6acf11fda98f4
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

2.02e-05191775e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

2.02e-051917759d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

2.02e-051917751c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAG1 DNAI4 CHD8 KIF2A TXK

2.07e-051927751c0ce299cee9ab5cdea256f3e8c1e5598577a8b6
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

2.07e-05192775d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

2.07e-05192775354adc1354bf596fbc60dd45c0169688e6f45165
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRACDL SPEF2 SAXO2 DNAI4 KIAA2012

2.12e-05193775e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

2.12e-051937750e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

2.12e-05193775ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

CRACDL SPEF2 SAXO2 DNAI4 PTPRT

2.23e-05195775fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRACDL SPEF2 SAXO2 DNAI4 KIAA2012

2.23e-05195775649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRACDL SPEF2 SAXO2 DNAI4 KIAA2012

2.23e-05195775d211a836cf711fdb91b10d512f09d462be937cc5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANTXR2 AEBP1 LTBP1 FBLIM1 VCL

2.23e-0519577549c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

CRACDL SPEF2 SAXO2 DNAI4 PTPRT

2.23e-0519577521dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellMild/Remission-B_naive-8|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

BPTF AEBP1 PEG10 ATAD2B KDM4B

2.23e-051957750a3221e4d1fa31a35868bdda0f0cc873c233b407
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANTXR2 AEBP1 LTBP1 FBLIM1 VCL

2.23e-05195775dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

CRACDL SPEF2 SAXO2 DNAI4 PTPRT

2.23e-05195775eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRACDL SPEF2 SAXO2 DNAI4 KIAA2012

2.23e-05195775129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRACDL SPEF2 SAXO2 DNAI4 KIAA2012

2.23e-051957753e70ee987d66d450062d5df3d7c733ccc7344470
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

2.28e-05196775de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 AEBP1 ZFHX3 LTBP1 VCL

2.28e-05196775b8759e6231e0254797d6c30930407b79440c57bb
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

BPTF KMT2C AHI1 PABPN1 KMT2A

2.28e-051967757bced0cc2112697593c478fa291b8ed3941fb811
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

CRACDL SPEF2 SAXO2 DNAI4 PTPRT

2.28e-0519677587d9881cfec461a5d89b688a83749b618c519485
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KMT2C PAG1 KMT2A CHD3 TXK

2.34e-0519777557ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRRC37A LRRC37A3 SPEF2 ZFHX2 SAXO2

2.34e-051977756e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPEF2 ERRFI1 DNAI4 KIAA2012 PTPRT

2.34e-05197775d83c61d2b5742e463122e1a98c7197a5b5b3d41b
ToppCell11.5-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

PAG1 AEBP1 ZFHX3 LTBP1 VCL

2.46e-051997751a8c77d241bd817a195e1532fd25f51358cb1ff1
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

REC8 BPTF SOBP KIF2A VCL

2.46e-05199775a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

2.52e-05200775926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPEF2 SAXO2 DNAI4 KIAA2012 PTPRT

2.52e-0520077506ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCellmLN-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

SETD1B ANTXR2 LAD1 CHD3 KIF2A

2.52e-052007753813fa1ee1462ba83fd8b6253070f46f0b063084
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal|6m / Sample Type, Dataset, Time_group, and Cell type.

STAC3 DNAI4 SLC4A5 RYR1 MYBPC1

2.52e-0520077513ec8afea86e4a10599c924871ba4e325b0a8013
ToppCellCOVID-19-Heart-Fib_+_CM|Heart / Disease (COVID-19 only), tissue and cell type

STAC3 ERRFI1 RYR1 MYBPC1

3.20e-051047740b60a56a46f1fe3f8224ec6399d009a34a117a21
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PEG10 LTBP1 DSCAML1 PTPRT

1.26e-041487745e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

SPEF2 DNAI4 KIAA2012 PTPRT

1.36e-041517748216462e723fec2797387929dde095370947e10a
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-liver_dendritic_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRRC37A C16orf86 TMEM79 STAC3

1.47e-04154774acfbde0fbc09fd69af62a81f8f63e14e36dd1ae0
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

SCN4A STAC3 RYR1 MYBPC1

1.51e-04155774d7e26696fd9c0a759524f331243db43059b33ed9
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PAG1 ZFHX3 CMYA5 CNGB1

1.58e-04157774b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REC8 DEF8 SAXO2 MFAP3L

1.83e-04163774132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

SPEF2 SAXO2 DNAI4 PTPRT

1.87e-041647740e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

REC8 LRRC37A SCN4A SAXO2

2.05e-041687748f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM79 LAD1 FAM83G CCNB1

2.05e-04168774f150beee37e0252951a88adcd9e3f0a22e5cfdd9
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOST STAC3 RBP3 FBLIM1

2.05e-04168774a8958b94ffc3423d56c250796dd253884b46f9d9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANTXR2 CMYA5 CNGB1 PTPRT

2.15e-04170774985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

SPEF2 DNAI4 CMYA5 PLEKHA7

2.20e-0417177474be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRACDL ZFHX2 CNGB1 PTPRT

2.20e-041717741854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AEBP1 GBX1 LTBP1 MYBPC1

2.30e-0417377430d67738633493d47f06ae452424382f069b6c0a
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAC3 LAD1 DNAI4 CMYA5

2.30e-04173774b6aed736d8480e3a6a5718aabd2fb79b1b75fa48
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REC8 FAM83G ZFHX2 PTPRT

2.35e-04174774f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LRRC37A PEG10 LRRC37A2 OTUD7B

2.35e-04174774a79ebb01a5849c314e02594a9c95009dbb03cb8c
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AEBP1 GBX1 LTBP1 ZNF579

2.35e-04174774a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RBP3 FAM83G CNGB1

2.43e-04707732121ba6a0beb2a8fdc589ff1063e7d8c2c3c68f6
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RBP3 FAM83G CNGB1

2.43e-0470773cd6bca68fe52f451716fc8c0b1745984bc9ec057
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RBP3 FAM83G CNGB1

2.43e-0470773be300c0447735aba89df4c3082b81eb5abf22770
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R10 CAST CMYA5 DHX9

2.45e-04176774749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOST ZFHX3 LTBP1 FBLIM1

2.50e-041777744553ee8cd9c24db6511b09fe49ed11a89e7cde9e
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SAXO2 DNAI4 KIAA2012 PTPRT

2.56e-04178774de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
DrugCaptopril [62571-86-2]; Down 200; 17.2uM; PC3; HT_HG-U133A

BPTF FAF2 SFSWAP PEG10 KMT2A LTBP1 KDM4B DHX9

1.49e-071797684585_DN
DrugNeostigmine bromide [114-80-7]; Down 200; 13.2uM; PC3; HT_HG-U133A

BPTF FAF2 SFSWAP PEG10 KMT2A LTBP1 DHX9

3.16e-061887676735_DN
Drughaloperidol; Up 200; 10uM; PC3; HT_HG-U133A

REC8 AHI1 CHMP6 CAST ZFHX2 SMG5 MFAP3L

4.45e-061987671203_UP
DrugNafcillin sodium salt monohydrate [7177-50-6]; Up 200; 8.8uM; HL60; HT_HG-U133A

TPSD1 CHMP6 SETD1B SLC19A1 PEG10 KMT2A MFAP3L

4.45e-061987672983_UP
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

BPTF CHMP6 SETD1B SLC19A1 ACIN1 SMG5

2.18e-051697665231_DN
DiseaseSezary Syndrome

KMT2C KMT2D BRD9 CHD3

7.19e-0727774C0036920
Diseasecongenital heart disease (implicated_via_orthology)

KMT2C KMT2D KMT2A CHD8 MYBPC1

1.05e-0669775DOID:1682 (implicated_via_orthology)
DiseaseKleefstra syndrome 2 (implicated_via_orthology)

KMT2C KMT2D

6.72e-062772DOID:0080598 (implicated_via_orthology)
DiseaseBladder Neoplasm

BPTF KMT2C KMT2D SLC19A1 KMT2A

3.36e-05140775C0005695
DiseaseMalignant neoplasm of urinary bladder

BPTF KMT2C KMT2D SLC19A1 KMT2A

3.48e-05141775C0005684
DiseaseRare disease with malignant hyperthermia

STAC3 RYR1

4.02e-054772cv:C5681128
Diseasemacula measurement

BPTF ATAD2B RBP3 CHD3 PLEKHA7

1.39e-04189775EFO_0008375
DiseaseProstatic Neoplasms

REC8 KMT2C KMT2D ANTXR2 FAF2 KMT2A ZFHX3 CHD3

2.05e-04616778C0033578
DiseaseMalignant neoplasm of prostate

REC8 KMT2C KMT2D ANTXR2 FAF2 KMT2A ZFHX3 CHD3

2.05e-04616778C0376358
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

KMT2C KMT2D PTPRT

2.24e-0445773DOID:3748 (is_implicated_in)
DiseaseL2 Acute Lymphoblastic Leukemia

PAG1 SLC19A1 KMT2A

3.07e-0450773C0023453
DiseaseChildhood Acute Lymphoblastic Leukemia

PAG1 SLC19A1 KMT2A

3.44e-0452773C0023452
DiseaseMacrocephaly

CHD8 CHD3

3.64e-0411772C0221355
DiseaseCongenital myopathy (disorder)

SCN4A RYR1

4.36e-0412772C0270960
DiseasePrecursor Cell Lymphoblastic Leukemia Lymphoma

PAG1 SLC19A1 KMT2A

5.51e-0461773C1961102
Diseaseprostate cancer (is_marker_for)

KMT2C KMT2D KMT2A KDM4B

7.54e-04156774DOID:10283 (is_marker_for)
DiseaseIntellectual Disability

BPTF KMT2C AHI1 ACIN1 CHD8 CHD3

1.12e-03447776C3714756
Diseasebreast cancer (is_marker_for)

KMT2D ZFHX3 KDM4B CCNB1

1.42e-03185774DOID:1612 (is_marker_for)
Diseasesensory peripheral neuropathy, remission

KMT2A PTPRT

1.64e-0323772EFO_0009785, MONDO_0002321
DiseaseRetinitis Pigmentosa

AHI1 RBP3 CNGB1

2.58e-03104773C0035334

Protein segments in the cluster

PeptideGeneStartEntry
EKEPEAEPPVPPQVS

ACIN1

941

Q9UKV3
GPIKPEPILPEPVQE

CHD8

606

Q9HCK8
AELPPKLPLQEEEPE

C16orf86

126

Q6ZW13
DPGKKVEVEPPPDRP

BRD9

111

Q9H8M2
PPEIKERSPPLSPEE

AHI1

1116

Q8N157
EKAPAPAPEERIEPP

AEBP1

276

Q8IUX7
PAPEERIEPPVKPLL

AEBP1

281

Q8IUX7
PAPAPKEEEEEPLPT

ANTXR2

356

P58335
PEVPSEPLPEKIPEN

CHMP6

171

Q96FZ7
SPILEEKDIPPLEFP

BPTF

216

Q12830
EAPEAPALPVVPELP

REC8

446

O95072
PPPAKKPEPDAREEQ

OTUD7B

661

Q6GQQ9
EAPIEPPVPPMEHEL

LRRC37A3

341

O60309
RLPSVEEAEVPKPLP

LAD1

61

O00515
EEPTPVEVPDKVLPP

MFAP3L

371

O75121
LSLVKEEPPEPVPSP

KMT2C

4021

Q8NEZ4
EAPIEPPVPPMEHEL

LRRC37A2

341

A6NM11
EAPIEPPVPPMEHEL

LRRC37A

341

A6NMS7
EEPPAEILPPPAEKS

FSCB

361

Q5H9T9
ELVPEEPSEPVPPLI

ATAD2B

1381

Q9ULI0
PPPLPAKEEPVEALT

LTBP1

771

Q14766
PLIDPKPVLEKPDEP

FAM47B

566

Q8NA70
PPPIEEECPEDLPEK

PEG10

71

Q86TG7
PEVPSEELEAKPRPI

KDM4B

511

O94953
KLPPISEEPPRVLEP

KIAA2012

391

Q0VF49
PPVPAKEEPEELPAA

PELP1

821

Q8IZL8
KEEPEELPAAPGPLP

PELP1

826

Q8IZL8
PKEAEPTPPVLPDEE

CRACDL

436

Q6NV74
AELIVKEPPTPIAPP

PTPRT

281

O14522
LVPDEEIEPSPETPP

KIF2A

66

O00139
EPEELLLEPEPEPEP

PABPN1

56

Q86U42
LLEPEPEPEPEEEPP

PABPN1

61

Q86U42
PEPEPEPEPVKEEKL

CCNB1

101

P14635
DELLPAREKVAEPPP

GBX1

151

Q14549
EPPDPPELEIREVKA

DSCAML1

886

Q8TD84
EPRKIPLEDEVPGVP

CHD3

1611

Q12873
LEEPKILVPPEPSEE

CMYA5

3396

Q8N3K9
PLLPEPEEKPKPRSE

CAST

351

P20810
VPDVTPEEALPELPP

DEF8

96

Q6ZN54
LPVLKEPEPEEPEDV

DNAI4

426

Q5VTH9
PMEEELPPPPAEPVE

FBLIM1

161

Q8WUP2
EEIELNISEIPPPPP

KANK4

301

Q5T7N3
DAEPLAPPIKPIKPV

KMT2A

1121

Q03164
PLPVEPKEEEPNLPL

KIAA1210

456

Q9ULL0
ELPPEPEPEPEPELE

RYR1

4486

P21817
PSLEPEEPKRPVPAE

MAP3K11

616

Q16584
EILPPPEDPSVPVAL

DHX9

296

Q08211
PMEKEPEPEPIVLPS

FAM83G

316

A6ND36
PAPPPEPEKEKEIHQ

SPEF2

916

Q9C093
PPPPDVQPVIDKLAE

SFSWAP

451

Q12872
LPPPYPLKEVEVPVV

TPSD1

176

Q9BZJ3
PPPEVIGIPLEDLDP

SCN4A

71

P35499
PVEKEEEPDPEPPPV

SMG5

426

Q9UPR3
ETEETPVPEPPKIAP

TMEM185A

306

Q8NFB2
KLECLPPEPSPDDPE

FAF2

346

Q96CS3
PPEPSPDDPESVKII

FAF2

351

Q96CS3
AKPKVEDEAPPRPPL

PLEKHA7

911

Q6IQ23
PPAKEVEARPPLSPE

SETD1B

1286

Q9UPS6
IIPELGEYPEPPPEL

SOST

36

Q9BQB4
DPEEEAPPPVPVKLL

PAG1

251

Q9NWQ8
SDEDKPEVPPRVPIP

ERRFI1

276

Q9UJM3
DVVPPIKPPKEIEDP

CLGN

256

O14967
LQPKEEPKEAPAPEP

CNGB1

221

Q14028
PEDLLPVPLPKPDPV

ZC3H6

881

P61129
LPEPPLASVEVPDKP

ZFHX2

1101

Q9C0A1
GELVVEEAPPPPPAV

RBP3

706

P10745
IPPPFIKPPAEDDVS

SOBP

131

A7XYQ1
PAVEKQVPVEPGPDP

SLC19A1

6

P41440
DIEPEPPESEPLTKL

TMEM79

96

Q9BSE2
PPESEPLTKLEELPE

TMEM79

101

Q9BSE2
DELAPPKPPLPEGEV

VCL

856

P18206
EHPKIEEPPIPPLEQ

UBE2O

751

Q9C0C9
DEEPQFPPPSVIKIP

SLC4A5

1096

Q9BY07
EIPPPEVKKVPEYVP

SAXO2

226

Q658L1
PLPPLPPSEVAEEKI

TXK

71

P42681
ADAPREPPPVELKPD

ZBTB17

186

Q13105
EEEEEEPPPEPPKLV

STAC3

71

Q96MF2
PPPPPLKAEQEEEGL

ZNF579

486

Q8NAF0
EPDPEPYEPIPPKLI

PPP1R10

506

Q96QC0
PYEPIPPKLIPLDEE

PPP1R10

511

Q96QC0
VSPLLPKLPEEPEAE

ZFHX3

3431

Q15911
EPLVELPTEPLAEPP

KMT2D

4931

O14686
KKEENEVPAPAPPPE

MYBPC1

6

Q00872