Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoCentral apnea

RPGRIP1L NR4A2 STIL DISP1

4.46e-0542254HP:0002871
HumanPhenoAbnormal fifth toe morphology

RPGRIP1L PLAA CHSY1 LBR FREM1

7.63e-0594255HP:0010322
HumanPhenoAbnormal posterior pituitary morphogenesis

VANGL2 BRAF STIL DISP1

1.30e-0455254HP:0011751
HumanPhenoMedian cleft palate

INTU LBR STIL DISP1

1.40e-0456254HP:0009099
HumanPhenoMedian cleft upper lip

INTU LBR STIL DISP1

1.40e-0456254HP:0000161
HumanPhenoMedian cleft lip and palate

INTU LBR STIL DISP1

1.40e-0456254HP:0008501
HumanPhenoCentral diabetes insipidus

BRAF STIL DISP1

1.51e-0422253HP:0000863
MousePhenoabnormal floor plate morphology

VANGL2 INTU RPGRIP1L STIL DISP1

7.21e-0740605MP:0000925
MousePhenoabsent floor plate

INTU RPGRIP1L STIL DISP1

1.41e-0620604MP:0000926
MousePhenoabnormal intestine morphology

DENND5B PPARGC1A RPGRIP1L MYO1A TLR2 TLR5 NDST4 LGR4 CHSY1 FREM1 TNS3

1.76e-055466011MP:0000477
DomainGOLGA6L

GOLGA6L10 GOLGA6L19 GOLGA6L9 GOLGA6L4

2.70e-096704IPR026737
DomainGOLGA2L5

GOLGA6L10 GOLGA6L19 GOLGA6L9 GOLGA6L4

5.32e-0718704PF15070
DomainGolgin_A

GOLGA6L10 GOLGA6L19 GOLGA6L9 GOLGA6L4

5.32e-0718704IPR024858
DomainLRR_8

LRRC57 TLR2 TLR5 LGR4 LRRN2 LRRC7 ERBIN

3.52e-06171707PF13855
DomainLeu-rich_rpt_typical-subtyp

LRRC57 TLR2 TLR5 LGR4 LRRN2 LRRC7 ERBIN

4.42e-06177707IPR003591
DomainLRR_TYP

LRRC57 TLR2 TLR5 LGR4 LRRN2 LRRC7 ERBIN

4.42e-06177707SM00369
DomainLRR

LRRC57 TLR2 TLR5 LGR4 LRRN2 LRRC7 ERBIN

1.02e-05201707PS51450
DomainLRR_1

LRRC57 TLR2 TLR5 LGR4 LRRN2 LRRC7 ERBIN

1.77e-05219707PF00560
DomainLeu-rich_rpt

LRRC57 TLR2 TLR5 LGR4 LRRN2 LRRC7 ERBIN

6.89e-05271707IPR001611
Domain-

LRRC57 TLR2 TLR5 LGR4 LRRN2 LRRC7 ERBIN

1.97e-043217073.80.10.10
DomainL_dom-like

LRRC57 TLR2 TLR5 LGR4 LRRN2 LRRC7 ERBIN

2.24e-04328707IPR032675
DomainPH_dom-like

FRMPD4 ARHGAP12 PSD3 OSBPL11 SHC4 MTMR10 TNS3

1.06e-03426707IPR011993
DomainPDZ

INTU FRMPD4 LRRC7 ERBIN

2.31e-03148704SM00228
Domain-

INTU FRMPD4 LRRC7 ERBIN

2.43e-031507042.30.42.10
DomainPDZ

INTU FRMPD4 LRRC7 ERBIN

2.49e-03151704PS50106
DomainPDZ

INTU FRMPD4 LRRC7 ERBIN

2.55e-03152704IPR001478
DomainTIR

TLR2 TLR5

2.78e-0321702SM00255
DomainTIR

TLR2 TLR5

3.05e-0322702PF01582
Domain-

TLR2 TLR5

3.33e-03237023.40.50.10140
Domain-

ARHGAP12 PSD3 OSBPL11 SHC4 MTMR10 TNS3

3.44e-033917062.30.29.30
DomainJmjC

KDM5A KDM3B

3.62e-0324702PF02373
DomainTIR

TLR2 TLR5

3.62e-0324702PS50104
DomainTIR_dom

TLR2 TLR5

3.93e-0325702IPR000157
DomainCys-rich_flank_reg_C

TLR2 TLR5 LRRN2

4.69e-0390703IPR000483
DomainLRRCT

TLR2 TLR5 LRRN2

4.69e-0390703SM00082
DomainTudor

LBR TDRD12

5.63e-0330702IPR002999
DomainProt-tyrosine_phosphatase-like

PTPRJ MTMR10 TNS3

6.12e-0399703IPR029021
DomainJMJC

KDM5A KDM3B

6.39e-0332702PS51184
DomainLRRCT

TLR2 TLR5

6.39e-0332702PF01463
DomainJmjC_dom

KDM5A KDM3B

6.39e-0332702IPR003347
DomainJmjC

KDM5A KDM3B

6.78e-0333702SM00558
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

BRAF KDM5A PSD3 KDM3B LARP1 TNKS1BP1 LBR STIL RAB11FIP1 ERBIN PALLD TNS3

2.26e-07861731236931259
Pubmed

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.

ADAM19 PTPRJ ARHGAP12 PSD3 OSBPL11 FAM91A1 RAB11FIP1 ERBIN

5.81e-0733973837232246
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

VANGL2 AHCTF1 CPEB4 TMEM131L LRRC7 LBR ERBIN

1.39e-0626373734702444
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

VANGL2 AHCTF1 ARHGAP12 PSD3 LARP1 TNKS1BP1 LRRC7 LBR ERBIN PALLD

2.25e-06708731039231216
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

RPGRIP1L PSD3 TMEM131L CHSY1 PALLD

2.52e-0610273510231032
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

VANGL2 LRRC57 BRAF PTPRJ PSD3 RAB11FIP1 ERBIN MTMR10 TNS3

3.02e-0656973930639242
Pubmed

A novel pathway of rapid TLR-triggered activation of integrin-dependent leukocyte adhesion that requires Rap1 GTPase.

TLR2 TLR5

4.35e-06273225057020
Pubmed

Senescence-Associated Secretory Phenotype Suppression Mediated by Small-Sized Mesenchymal Stem Cells Delays Cellular Senescence through TLR2 and TLR5 Signaling.

TLR2 TLR5

4.35e-06273233401590
Pubmed

Genetic variants of toll-like receptor 2 and 5, helicobacter pylori infection, and risk of gastric cancer and its precursors in a chinese population.

TLR2 TLR5

4.35e-06273221994405
Pubmed

Microbial patterns signaling via Toll-like receptors 2 and 5 contribute to epithelial repair, growth and survival.

TLR2 TLR5

4.35e-06273218167552
Pubmed

Activation of TLR2 and TLR5 did not affect tumor progression of an oral squamous cell carcinoma, YD-10B cells.

TLR2 TLR5

4.35e-06273220456615
Pubmed

Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans.

TLR2 TLR5

4.35e-0627329596645
Pubmed

Pseudomonas aeruginosa flagella activate airway epithelial cells through asialoGM1 and toll-like receptor 2 as well as toll-like receptor 5.

TLR2 TLR5

4.35e-06273214607814
Pubmed

Mucoid Pseudomonas aeruginosa caused by mucA mutations result in activation of TLR2 in addition to TLR5 in airway epithelial cells.

TLR2 TLR5

4.35e-06273223068105
Pubmed

REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps.

REV3L REV1

4.35e-06273234508659
Pubmed

ELYS regulates the localization of LBR by modulating its phosphorylation state.

AHCTF1 LBR

4.35e-06273227802161
Pubmed

[Association between toll-like receptors 2 and 5 polymorphisms and neonatal sepsis].

TLR2 TLR5

4.35e-06273226695672
Pubmed

Polymorphisms in translesion polymerase genes influence treatment outcome in malignant mesothelioma.

REV3L REV1

4.35e-06273224956248
Pubmed

Virus like particles of GII.4 norovirus bind Toll Like Receptors 2 and 5.

TLR2 TLR5

4.35e-06273231154053
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SEC16B UBN1 BRAF KDM5A OSBPL11 KDM3B LARP1 FAM91A1 TNKS1BP1 ERBIN

4.94e-06774731015302935
Pubmed

Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1.

REV3L REV1

1.30e-05373220164194
Pubmed

Increased expression of toll-like receptors (TLR) 2, 4 and 5 in gastric dysplasia.

TLR2 TLR5

1.30e-05373221455638
Pubmed

Helicobacter pylori induces interleukin-8 secretion by Toll-like receptor 2- and Toll-like receptor 5-dependent and -independent pathways.

TLR2 TLR5

1.30e-05373215731050
Pubmed

The vital role of polymerase ζ and REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and recruitment of polymerase ζ by REV1 to replication-stalled site.

REV3L REV1

1.30e-05373222303021
Pubmed

Attenuated TLRs in middle ear mucosa contributes to susceptibility of chronic suppurative otitis media.

TLR2 TLR5

1.30e-05373224882571
Pubmed

Histone lysine demethylases in breast cancer.

KDM5A KDM3B

1.30e-05373223266085
Pubmed

TLR expression on neutrophils at the pulmonary site of infection: TLR1/TLR2-mediated up-regulation of TLR5 expression in cystic fibrosis lung disease.

TLR2 TLR5

1.30e-05373218684966
Pubmed

Sertoli cells initiate testicular innate immune responses through TLR activation.

TLR2 TLR5

1.30e-05373217082629
Pubmed

Nuclear orphan receptor NR4A2 modulates fatty acid oxidation pathways in colorectal cancer.

PPARGC1A NR4A2

1.30e-05373221757690
Pubmed

The presence of functionally relevant toll-like receptor polymorphisms does not significantly correlate with development or outcome of sepsis.

TLR2 TLR5

1.30e-05373221721932
Pubmed

Ligand-induced differential cross-regulation of Toll-like receptors 2, 4 and 5 in intestinal epithelial cells.

TLR2 TLR5

1.30e-05373217493681
Pubmed

Induction of human β-defensin-2 in pulmonary epithelial cells by Legionella pneumophila: involvement of TLR2 and TLR5, p38 MAPK, JNK, NF-κB, and AP-1.

TLR2 TLR5

1.30e-05373220154223
Pubmed

Activation of toll-like receptors 2, 3 or 5 induces matrix metalloproteinase-1 and -9 expression with the involvement of MAPKs and NF-kappaB in human epidermal keratinocytes.

TLR2 TLR5

1.30e-05373219758322
Pubmed

Control of Pseudomonas aeruginosa in the lung requires the recognition of either lipopolysaccharide or flagellin.

TLR2 TLR5

1.30e-05373218566425
Pubmed

Polymorphisms in toll-like receptors 2, 4 and 5 are associated with Legionella pneumophila infection.

TLR2 TLR5

1.30e-05373223526294
Pubmed

REV3 and REV1 play major roles in recombination-independent repair of DNA interstrand cross-links mediated by monoubiquitinated proliferating cell nuclear antigen (PCNA).

REV3L REV1

1.30e-05373216571727
Pubmed

TLR2, TLR3 and TLR5 regulation of pro-inflammatory and pro-labour mediators in human primary myometrial cells.

TLR2 TLR5

1.30e-05373228844021
Pubmed

REV1 and polymerase ζ facilitate homologous recombination repair.

REV3L REV1

1.30e-05373221926160
Pubmed

Translesion synthesis mechanisms depend on the nature of DNA damage in UV-irradiated human cells.

REV3L REV1

1.30e-05373227095204
Pubmed

Association between TLR2, TLR4, and TLR5 genetic variants and the risk of hepatocellular carcinoma in Moroccan population.

TLR2 TLR5

1.30e-05373237330637
Pubmed

Repair of cisplatin-induced DNA interstrand crosslinks by a replication-independent pathway involving transcription-coupled repair and translesion synthesis.

REV3L REV1

1.30e-05373222810206
Pubmed

Structural basis of recruitment of DNA polymerase ζ by interaction between REV1 and REV7 proteins.

REV3L REV1

1.30e-05373222859296
Pubmed

Toll-like receptor (TLR2, TLR4 and TLR5) gene polymorphisms and Helicobacter pylori infection in children with and without duodenal ulcer.

TLR2 TLR5

1.30e-05373218809506
Pubmed

Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.

PPARGC1A BRAF

1.30e-05373223477830
Pubmed

Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7.

REV3L REV1

1.30e-05373211485998
Pubmed

Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links.

REV3L REV1

1.30e-05373220028736
Pubmed

Activation of Toll-like receptor 5 in microglia modulates their function and triggers neuronal injury.

TLR2 TLR5

1.30e-05373232912327
Pubmed

Crystallization and X-ray diffraction analysis of the ternary complex of the C-terminal domain of human REV1 in complex with REV7 bound to a REV3 fragment involved in translesion DNA synthesis.

REV3L REV1

1.30e-05373222869133
Pubmed

TLR 5, but neither TLR2 nor TLR4, is involved in lung epithelial cell response to Burkholderia cenocepacia.

TLR2 TLR5

1.30e-05373218680520
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

INTU FRMPD4 PSD3 FAM91A1 LRRC7 ULK2 ERBIN

2.39e-0540773712693553
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

LRRC57 PTPRJ LARP1 FAM91A1 TNKS1BP1 LRRC7 LBR ERBIN

2.46e-0556573825468996
Pubmed

Induction of TLR-2 and TLR-5 expression by Helicobacter pylori switches cagPAI-dependent signalling leading to the secretion of IL-8 and TNF-α.

TLR2 TLR5

2.60e-05473221573018
Pubmed

Metagenomic analysis of the effects of toll-like receptors on bacterial infection in the peritoneal cavity following cecum ligation and puncture in mice.

TLR2 TLR5

2.60e-05473231348811
Pubmed

Upregulation of Toll-Like Receptors 2, 5, 7, and 9 in the Cervical Epithelial Cells of Iranian Women Infected with High-Risk Human Papilloma Virus.

TLR2 TLR5

2.60e-05473236377984
Pubmed

Lgr4/Gpr48 negatively regulates TLR2/4-associated pattern recognition and innate immunity by targeting CD14 expression.

TLR2 LGR4

2.60e-05473223589304
Pubmed

Damaged spermatogenic cells induce inflammatory gene expression in mouse Sertoli cells through the activation of Toll-like receptors 2 and 4.

TLR2 TLR5

2.60e-05473223123736
Pubmed

The C-terminal domain of human Rev1 contains independent binding sites for DNA polymerase η and Rev7 subunit of polymerase ζ.

REV3L REV1

2.60e-05473222828282
Pubmed

Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells.

TLR2 TLR5

2.60e-05473217128265
Pubmed

NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection.

PPARGC1A NR4A2

2.60e-05473220566846
Pubmed

Nod2 is required for antigen-specific humoral responses against antigens orally delivered using a recombinant Lactobacillus vaccine platform.

TLR2 TLR5

2.60e-05473229734365
Pubmed

Source of biomass cooking fuel determines pulmonary response to household air pollution.

TLR2 TLR5

2.60e-05473224102120
Pubmed

Distinct roles for MyD88 and Toll-like receptors 2, 5, and 9 in phagocytosis of Borrelia burgdorferi and cytokine induction.

TLR2 TLR5

2.60e-05473218378636
Pubmed

Differences in the expression of TLRs and inflammatory cytokines in pre-eclamptic compared with healthy pregnant women.

TLR2 TLR5

2.60e-05473225549591
Pubmed

Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) ζ, and Pol κ.

REV3L REV1

2.60e-05473222859295
Pubmed

Toll-like receptor signaling in airborne Burkholderia thailandensis infection.

TLR2 TLR5

2.60e-05473219797072
Pubmed

Rev1 contributes to proper mitochondrial function via the PARP-NAD+-SIRT1-PGC1α axis.

PPARGC1A REV1

2.60e-05473228970491
Pubmed

Expression patterns and functions of toll-like receptors in mouse sertoli cells.

TLR2 TLR5

2.60e-05473218499758
Pubmed

Suppression of Toll-like receptor-mediated innate immune responses at the ocular surface by the membrane-associated mucins MUC1 and MUC16.

TLR2 TLR5

2.60e-05473225563498
Pubmed

The effects of oral and enteric Campylobacter concisus strains on expression of TLR4, MD-2, TLR2, TLR5 and COX-2 in HT-29 cells.

TLR2 TLR5

4.33e-05573223437263
Pubmed

The toll-like receptor signaling molecule Myd88 contributes to pancreatic beta-cell homeostasis in response to injury.

TLR2 TLR5

4.33e-05573219357791
Pubmed

Toll-like receptor 11 (TLR11) prevents Salmonella penetration into the murine Peyer patches.

TLR2 TLR5

4.33e-05573223135279
Pubmed

Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice.

TLR2 TLR5

4.33e-05573222826298
Pubmed

A comprehensive genotype-phenotype interaction of different Toll-like receptor variations in a renal transplant cohort.

TLR2 TLR5

4.33e-05573220604744
Pubmed

Rev7 dimerization is important for assembly and function of the Rev1/Polζ translesion synthesis complex.

REV3L REV1

4.33e-05573230111544
Pubmed

Long-range comparison of human and mouse SCL loci: localized regions of sensitivity to restriction endonucleases correspond precisely with peaks of conserved noncoding sequences.

CYP4X1 STIL

4.33e-05573211156618
Pubmed

Differential regulation of the PGC family of genes in a mouse model of Staphylococcus aureus sepsis.

PPARGC1A TLR2

4.33e-05573220657826
Pubmed

The expression of Toll-like receptors 2, 4, 5, 7 and 9 in Merkel cell carcinoma.

TLR2 TLR5

4.33e-05573225862837
Pubmed

Microbial antigen mimics activate diabetogenic CD8 T cells in NOD mice.

TLR2 TLR5

4.33e-05573227621416
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

RPGRIP1L UBN1 STIL NNT PALLD

4.41e-0518473532908313
Pubmed

Lynch Syndrome

BRAF PTPRJ TLR2

4.63e-053373320301390
Pubmed

Host PDZ-containing proteins targeted by SARS-CoV-2.

FRMPD4 LRRC7 ERBIN

5.53e-053573333864728
Pubmed

Systems biology of innate immunity.

TLR2 TLR5

6.48e-05673219120490
Pubmed

Validation of the use of DNA pools and primer extension in association studies of sporadic colorectal cancer for selection of candidate SNPs.

GSTP1 PPARGC1A

6.48e-05673216395669
Pubmed

Interaction of hREV1 with three human Y-family DNA polymerases.

REV3L REV1

6.48e-05673215189446
Pubmed

MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists.

TLR2 TLR5

6.48e-05673217202381
Pubmed

Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors.

TLR2 TLR5

6.48e-05673210426995
Pubmed

Contributions of MyD88-dependent receptors and CD11c-positive cells to corneal epithelial barrier function against Pseudomonas aeruginosa.

TLR2 TLR5

6.48e-05673229062042
Pubmed

PKC-alpha controls MYD88-dependent TLR/IL-1R signaling and cytokine production in mouse and human dendritic cells.

TLR2 TLR5

6.48e-05673219950169
Pubmed

Delineation of the role of Toll-like receptor signaling during peritonitis by a gradually growing pathogenic Escherichia coli.

TLR2 TLR5

6.48e-05673221690093
Pubmed

The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota.

TLR2 TLR5

6.48e-05673235028606
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

CPEB4 CNTNAP3 ZFHX2 TNKS1BP1

6.50e-0510273411214970
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

PPARGC1A PLAA BRAF AHCTF1 OSBPL11 LGR4 TMEM131L FAM91A1 ULK2 ERBIN

8.70e-051084731011544199
Pubmed

Polymorphisms of toll like receptors in the genetics of severe RSV associated diseases.

TLR2 TLR5

9.06e-05773218776592
Pubmed

Transitions in oral and intestinal microflora composition and innate immune receptor-dependent stimulation during mouse development.

TLR2 TLR5

9.06e-05773219933833
Pubmed

Paired Ig-like receptors bind to bacteria and shape TLR-mediated cytokine production.

TLR2 LILRB5

9.06e-05773217371981
Pubmed

IL1RN VNTR and IL2-330 polymorphic genes are independently associated with chronic immune thrombocytopenia.

TLR2 TLR5

9.06e-05773220626741
Pubmed

Gene polymorphisms in Toll-like receptors, interleukin-10, and interleukin-10 receptor alpha and lymphoma risk.

TLR2 TLR5

9.06e-05773216971956
Pubmed

IL2-330G polymorphic allele is associated with decreased risk of Helicobacter pylori infection in adulthood.

TLR2 TLR5

9.06e-05773219638314
Pubmed

Pseudomonas aeruginosa LPS or flagellin are sufficient to activate TLR-dependent signaling in murine alveolar macrophages and airway epithelial cells.

TLR2 TLR5

9.06e-05773219806220
Pubmed

Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.

TLR2 TLR5

9.06e-05773220016852
InteractionRAC1 interactions

VANGL2 GSTP1 PTPRJ ARHGAP12 TLR2 PSD3 OSBPL11 LGR4 FAM91A1 LBR RAB11FIP1 ERBIN MTMR10 TNS3

8.42e-0610636714int:RAC1
InteractionYWHAH interactions

RPGRIP1L BRAF KDM5A PSD3 KDM3B LARP1 TNKS1BP1 LBR STIL RAB11FIP1 ERBIN MTMR10 PALLD TNS3

1.27e-0511026714int:YWHAH
InteractionKCNA3 interactions

VANGL2 AHCTF1 ARHGAP12 PSD3 LARP1 TNKS1BP1 LRRC7 TRPM1 LBR ERBIN PALLD TDRD12

2.64e-058716712int:KCNA3
Cytoband15q25.2

GOLGA6L10 GOLGA6L9 GOLGA6L4

4.36e-054372315q25.2
Cytoband15q13.3

TRPM1 MTMR10

7.69e-042672215q13.3
Cytoband9q33.2

OR1L6 OR1L4

1.73e-03397229q33.2
CytobandEnsembl 112 genes in cytogenetic band chr15q25

GOLGA6L10 GOLGA6L9 GOLGA6L4

2.08e-03160723chr15q25
GeneFamilyCD molecules|Toll like receptors

TLR2 TLR5

3.46e-0410512948
GeneFamilyPDZ domain containing

INTU FRMPD4 LRRC7 ERBIN

8.83e-041525141220
GeneFamilyDNA polymerases

REV3L REV1

1.90e-0323512535
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5A KDM3B

2.07e-0324512485
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RPGRIP1L RAB11FIP1

4.62e-0336512823
GeneFamilyTudor domain containing

LBR TDRD12

4.88e-0337512780
GeneFamilyOlfactory receptors, family 1

OR1L6 OR1L4

5.68e-0340512147
CoexpressionLAKE_ADULT_KIDNEY_C20_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_A_CORTEX

PPARGC1A BRAF PTPRJ CPEB4 PSD3 LGR4 FREM1

1.53e-07152697M39239
CoexpressionLAKE_ADULT_KIDNEY_C21_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_B

PPARGC1A PTPRJ PSD3 LGR4 FREM1

7.82e-06103695M39240
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

PPARGC1A ADAM19 CPEB4 PSD3 LRRC7 PALLD

6.63e-071887366d249fe92d51a19da19ec14bb2262d394255d577
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Serpinf1-Serpinf1_Aqp5_Vip|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GLYAT INTU CNTNAP3 ERBIN FREM1

2.98e-061367358f5682422ba0b477c1e0700212948457f106cb10
ToppCellfacs-Skin-nan-24m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 ODAD2 KIAA2012 PALLD TNS3

1.02e-05175735f1166b567bca80dac3abe90c3dc544c831006640
ToppCellCOVID-19-kidney-CD-IC-A|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPARGC1A PSD3 LGR4 LRRN2 FREM1

1.05e-0517673545028197364c64e93e3ffe86aff773d47a477d49
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A FRMPD4 PSD3 LGR4 FREM1

1.17e-05180735cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A CPEB4 PSD3 LGR4 FREM1

1.37e-05186735a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A CPEB4 PSD3 LGR4 FREM1

1.44e-05188735e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAM19 NDST4 LGR4 LRRC7 PALLD

1.44e-051887353004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

PPARGC1A CPEB4 PSD3 LRRC7 PALLD

1.56e-051917355d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GLYAT PPARGC1A PTPRJ CPEB4 LGR4

1.63e-0519373582e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYO1A TLR2 PSD3 LILRB5 TNS3

1.85e-05198735c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VANGL2 PPARGC1A LRRN2 MTMR10 FREM1

1.89e-051997353cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRJ PSD3 LRRN2 FREM1

1.08e-0415073487968ce885a4959616f0321f58517fe8029ba1b1
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND5B PPARGC1A INTU TCAIM

1.29e-04157734bd45590da540a557dc8096980a45220fccb99505
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND5B PPARGC1A INTU TCAIM

1.29e-0415773400c9a58b033b8b95b0d838f233dd077b62d8b02a
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

INTU RPGRIP1L CNTNAP3 STIL

1.29e-04157734410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 SHC4 LRRC7 TRPM1

1.42e-041617347d1bc73f4c82465b3f489d6737048b0cd54f22cf
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 SHC4 LRRC7 TRPM1

1.42e-04161734410eef62c83c704cbfc5a1b643c4db11bbdcd81f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 SHC4 LRRC7 TRPM1

1.42e-0416173471022485da6754a2b57b4c3e758e3de4c95cc292
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 SHC4 LRRC7 TRPM1

1.42e-0416173459ae8a7c9a04ecaa335b8064852a5a91a21780bd
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A CPEB4 LGR4 LRRN2

1.45e-0416273436ddebe3bb172c992739353b7b049b2dde98b559
ToppCellBasal_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

VANGL2 FRMPD4 CHSY1 TDRD12

1.52e-0416473485487a303194f5244956ec1ca2d1758d38117f41
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A PTPRJ CPEB4 ODAD2

1.52e-04164734d847d509bb1791638032ade6755d8164586b5bd5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A PTPRJ CPEB4 ODAD2

1.60e-041667346fe8db8d45177a78605681f22e04fa8d0594f2df
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WSCD2 GDF9 PALLD FREM1

1.71e-0416973416c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYO1A GDF9 PALLD FREM1

1.75e-041707347fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

PTPRJ TLR2 CPEB4 PALLD

1.75e-041707344232fe937909f93d3736988c707b8f95ce993398
ToppCellileum|World / shred on tissue and cell subclass

DENND5B SEC16B MYO1A KDM5A

1.75e-041707349f1211bd4287620e19a59f21e6ecdca3e42e0260
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP12 LGR4 LRRC7 LILRB5

1.79e-041717347c8304573b892ef9ea4e048cba9ea9fbab848dcd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRJ PSD3 ODAD2 FREM1

1.95e-041757341d8da48236549c01381f777ce5b2937f9f86acc2
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MYO1A TLR5 STIL

2.07e-0470733e1ac00f4a519b6ada89f591e549874bd3eed0ca1
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MYO1A TLR5 STIL

2.07e-047073327e12c0f43a996bcbed285c5ee668bef5a786d80
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MYO1A TLR5 STIL

2.07e-0470733b6815131e87e81c10e65bc398a84dab5a74b32ac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRJ PSD3 LGR4 FREM1

2.22e-0418173430729f0364f719c044712a51453e22dc2c1a232b
ToppCellCOVID-19-kidney-CD-IC-B|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPARGC1A FRMPD4 LGR4 FREM1

2.27e-04182734ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 NDST4 TMEM131L PALLD

2.27e-04182734f00eec1f434d92d44787d3d3343476c98c3de5b4
ToppCell5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLR2 TLR5 NR4A2 LILRB5

2.27e-04182734de15a77b8d3527638bea5b04e0b2af03ac93bc18
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A CPEB4 LGR4 NNT

2.32e-041837342f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A CPEB4 LGR4 FREM1

2.32e-041837342e831a4d99c6f983793df71c0994124c943c6da9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A FRMPD4 ODAD2 FREM1

2.36e-041847342cbed6462fea2622871bb7e49b0df3d984239281
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TLR2 NR4A2 CHSY1 LILRB5

2.36e-04184734d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A FRMPD4 ODAD2 FREM1

2.36e-04184734ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A FRMPD4 ODAD2 FREM1

2.36e-041847342b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

ADAM19 AHCTF1 TMEM131L LBR

2.41e-04185734a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellP03|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NR4A2 PALLD FREM1 TNS3

2.41e-04185734a07dbe1f76e40734a28826423a5cc64b8e56af5e
ToppCell5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLR2 TLR5 NR4A2 LILRB5

2.46e-04186734c0a58e43a813441d3a1708236737b15db8bea10e
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ADAM19 CNTNAP3 PALLD FREM1

2.46e-04186734cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TLR2 TLR5 CNTNAP3 RAB11FIP1

2.51e-0418773475bc05a0ba2727fecc236903ace792a28f3d3c9a
ToppCellCOVID-19-kidney-CD-IC-B|kidney / Disease (COVID-19 only), tissue and cell type

PPARGC1A FRMPD4 PSD3 FREM1

2.51e-04187734ce05b89860573fe0356102e2998d1ef6d1968034
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TLR2 TLR5 CNTNAP3 RAB11FIP1

2.51e-04187734a0d59bf1043ff5a1e8110b39ecc2d3932675edd4
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LGR4 SHC4 PALLD DISP1

2.57e-04188734116ca07ee4413dcc0e9e5ac99bfee6ed7b7847c6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A CPEB4 LGR4 FREM1

2.57e-04188734bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A CPEB4 LGR4 FREM1

2.57e-04188734eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A CPEB4 LGR4 FREM1

2.62e-04189734977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A CPEB4 LGR4 FREM1

2.62e-04189734975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A CPEB4 LGR4 FREM1

2.62e-041897347eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

LGR4 PALLD FREM1 TNS3

2.62e-041897340c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

PPARGC1A CPEB4 PSD3 PALLD

2.62e-041897340a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

PPARGC1A CPEB4 PSD3 PALLD

2.67e-0419073493c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

PPARGC1A CPEB4 PSD3 PALLD

2.67e-04190734de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 TMEM131L LRRC7 PALLD

2.67e-04190734562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

INTU RPGRIP1L CNTNAP3 STIL

2.67e-04190734250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 TMEM131L LRRC7 PALLD

2.67e-04190734f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

PPARGC1A CPEB4 PSD3 PALLD

2.67e-04190734fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A CPEB4 LGR4 FREM1

2.67e-04190734e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

PPARGC1A CPEB4 PSD3 PALLD

2.72e-0419173425f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

CHSY1 PALLD FREM1 TNS3

2.72e-041917343379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

ADAM19 AHCTF1 TMEM131L LBR

2.72e-041917349454f642c3621370fa23640b631301346b300950
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

PPARGC1A CPEB4 NNT PALLD

2.78e-04192734ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

BRAF ARHGAP12 MAP4K2 GOLGA6L4

2.78e-04192734efbd52b3d2b6d3fb9ed6bc3f36aca9f4f1fcbc49
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRMPD4 LRRC7 REV3L PALLD

2.83e-041937344aa976b596830b585e8d9c808d5072ed23d13a7c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND5B ADAM19 BRAF NR4A2

2.83e-04193734bbea475d2c4c7b29674ff302529f8f83dd666dcb
ToppCellCTRL-Myeloid-Alveolar_Macrophage|Myeloid / Disease state, Lineage and Cell class

GSTP1 PSD3 OSBPL11 TMEM131L

2.83e-0419373480871d963c23a6befe58e5e60b7f7d1a1b227ce2
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

PPARGC1A ADAM19 CPEB4 PALLD

2.83e-04193734dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAM19 FRMPD4 NDST4 LGR4

2.83e-04193734000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRMPD4 LRRC7 REV3L PALLD

2.83e-041937345578f7cb3ec68c9a38cc5304b618b81283024d5e
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PPARGC1A ARHGAP12 CNTNAP3 TMEM131L

2.83e-04193734c4b22b62f3cc7bf0ec0eba76e1504c236290bbc9
ToppCellCOVID-19-Heart-Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

PTPRJ TLR2 LILRB5 TNS3

2.89e-04194734f09675cd472200363c458952f00d2e41990800ee
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PSD3 SHC4 RAB11FIP1 FREM1

2.89e-041947344579b4a44f7c731553a284843c296866027d7c0e
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

PPARGC1A ADAM19 PSD3 PALLD

2.89e-0419473489812fb164065041357bb37a3c2d87028ec3de4e
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

PPARGC1A CPEB4 PSD3 PALLD

2.89e-04194734c3535f7cc0076653c72db582047cff053c322397
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ADAM19 FRMPD4 NDST4 LGR4

2.89e-0419473467f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

PPARGC1A CPEB4 PSD3 PALLD

2.95e-0419573475fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellControl-Classical_Monocyte-cMono_2|Control / Disease condition and Cell class

TLR2 NR4A2 RAB11FIP1 ERBIN

2.95e-041957340fea64ee3eedf3929abb0dd9c5f5fc72f181eed9
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 NR4A2 LGR4 PALLD

2.95e-04195734f41a68b7c2621594db8d8952e301eeadc96be26f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PSD3 SHC4 RAB11FIP1 FREM1

2.95e-041957343d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCellCOVID-19-lung-Macrophage_metabolically_active|lung / Disease (COVID-19 only), tissue and cell type

PTPRJ TLR2 LILRB5 TNS3

3.01e-04196734a753d76d764c181eecb0e17a794a2e7d0ff70136
ToppCellcontrol-immature_Neutrophil|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TLR5 NR4A2 FAM91A1 TNS3

3.01e-04196734e34fd3e7a5b1c22a81fd3208e6d58bdb846d51c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A PTPRJ CPEB4 LGR4

3.01e-041967346ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A PTPRJ CPEB4 LGR4

3.01e-04196734eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

INTU LRRC7 REV3L FREM1

3.06e-04197734fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellMonocytes-cDCs|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

DENND5B GSTP1 ADAM19 RAB11FIP1

3.06e-0419773415cb9fe1c3bab80bd24728fd9ac7ba385912ac33
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VANGL2 FRMPD4 PSD3 LGR4

3.06e-04197734107cb153ea7fc74bbd244dbb9d0499c0a8506724
ToppCellcontrol-Myeloid-Non-resident_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TLR2 KDM3B RAB11FIP1 ERBIN

3.06e-04197734df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCellCaecum-(6)_Macrophage-(61)_LYVE1_Macrophage|Caecum / shred on region, Cell_type, and subtype

TLR2 TLR5 PALLD LILRB5

3.12e-04198734e684c3934c163aef4d284b69435832d2c9614f2a
ToppCellCaecum-Macrophage-LYVE1_Macrophage|Caecum / Region, Cell class and subclass

TLR2 TLR5 PALLD LILRB5

3.12e-04198734a92c0cacb775aca6bbb302bd9e22c081a112a44d
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SEC16B WSCD2 LRRN2 DISP1

3.18e-04199734fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ADAM19 NR4A2 LRRN2 PALLD

3.18e-04199734a207b4891881149d4c50721310690fd794157723
ToppCell5'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GSTP1 CYP4X1 RAB11FIP1 FREM1

3.18e-04199734f544229f471b4717166dd4b588399afe45cc31b5
ToppCellMild/Remission-B_intermediate-0|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PTPRJ NR4A2 RAB11FIP1 TNS3

3.18e-04199734592111591f0f6816fc56620cb555eb48dabf0758
DiseaseColorectal cancer

BRAF PTPRJ TLR2

2.87e-0527653cv:C0346629
DiseaseCOLORECTAL CANCER

BRAF PTPRJ TLR2

2.87e-0527653114500
DiseaseNeoplasm of the large intestine

BRAF PTPRJ TLR2

2.87e-0527653cv:C0009404
Diseasemalignant astrocytoma (is_implicated_in)

GSTP1 BRAF

4.76e-055652DOID:3069 (is_implicated_in)
Diseaseciliopathy (implicated_via_orthology)

VANGL2 RPGRIP1L MAP4K2

9.51e-0540653DOID:0060340 (implicated_via_orthology)
DiseaseColon Carcinoma

BRAF PTPRJ

1.70e-049652C0699790
Diseasecocaine use measurement

PSD3 OR1L4

2.59e-0411652EFO_0010553
Diseasemean platelet volume

ADAM19 UBN1 PTPRJ CPEB4 PSD3 TMEM131L STIL NNT ULK2

3.83e-041020659EFO_0004584
Diseasesevere acute respiratory syndrome, COVID-19

PPARGC1A FRMPD4 PSD3 OSBPL11 TRPM1 ODAD2

4.54e-04447656EFO_0000694, MONDO_0100096
DiseaseMalignant Glioma

GSTP1 BRAF PSD3

5.03e-0470653C0555198
Diseasemixed gliomas

GSTP1 BRAF PSD3

5.03e-0470653C0259783
DiseaseAbnormal behavior

NR4A2 KDM3B

5.62e-0416652C0233514
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

TLR2 TLR5

6.36e-0417652DOID:8677 (biomarker_via_orthology)
DiseaseParkinson's disease (is_implicated_in)

GSTP1 PPARGC1A NR4A2

6.39e-0476653DOID:14330 (is_implicated_in)
DiseaseCannabis use, age at onset

LARP1 LRRC7

7.98e-0419652EFO_0004847, EFO_0007585
Diseasealcohol use disorder (implicated_via_orthology)

KDM5A PSD3 KDM3B MAP4K2

9.14e-04195654DOID:1574 (implicated_via_orthology)
DiseaseGlioma

GSTP1 BRAF PSD3

9.48e-0487653C0017638
Diseasecholangiocarcinoma (is_implicated_in)

GSTP1 BRAF

1.07e-0322652DOID:4947 (is_implicated_in)
Diseaselung disease (is_implicated_in)

GSTP1 TLR2

1.07e-0322652DOID:850 (is_implicated_in)
Diseaseobesity (implicated_via_orthology)

GSTP1 PPARGC1A SEC16B ZFHX2

1.31e-03215654DOID:9970 (implicated_via_orthology)
DiseaseAcute kidney injury

TLR5 DISP1

1.39e-0325652HP_0001919
Diseaseatopic dermatitis (is_implicated_in)

GSTP1 TLR2

1.50e-0326652DOID:3310 (is_implicated_in)
DiseaseL lactate dehydrogenase measurement

PTPRJ LILRB5

1.50e-0326652EFO_0004808
Diseaseforced expiratory volume

ADAM19 ARHGAP12 PSD3 LARP1 STIL KIAA2012 NNT

1.73e-03789657EFO_0004314
Diseasecorneal topography

INTU CHSY1 STIL

1.81e-03109653EFO_0004345
DiseaseMyeloid Leukemia, Chronic

GSTP1 BRAF

1.87e-0329652C0023473
Diseasepancreatic cancer (is_implicated_in)

GSTP1 BRAF PALLD

1.96e-03112653DOID:1793 (is_implicated_in)
DiseaseHuntington disease, disease progression measurement

TRPM1 MTMR10

2.00e-0330652EFO_0008336, MONDO_0007739
Diseaseosteoporosis (is_implicated_in)

GSTP1 LGR4

2.13e-0331652DOID:11476 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
YNPALLNLPKSVLAK

VANGL2

286

Q9ULK5
AFGETKTKTLPLPNL

AZI2

361

Q9H6S1
PISKLPDGFSQLLNL

ERBIN

126

Q96RT1
LPGSLTNVKALQKSP

BRAF

406

P15056
GKLKLSLFQPGQSPR

CNTNAP3

426

Q9BZ76
LKPQQPGLKPFLQSA

AMBN

116

Q9NP70
QNNKLGQLKPSALPS

ADAM19

726

Q9H013
GQLKPSALPSKLRQQ

ADAM19

731

Q9H013
GQIPLPKKLQCSAFS

DISP1

1141

Q96F81
KLTPLILKPFGNSIS

LBR

116

Q14739
SNNKIESLPPLLIGK

LRRC57

46

Q8N9N7
LQKFLLLKNFSSPLP

MAP4K2

631

Q12851
SNLKTLPKGLSASLP

LARP1

536

Q6PKG0
KKDFIATQGPLPNTL

PTPRJ

1106

Q12913
PISKNIKQSLALSPG

RPGRIP1L

1091

Q68CZ1
LGPNQKLKFNPTELI

MTMR10

121

Q9NXD2
PISKLPDGFTQLLNL

LRRC7

126

Q96NW7
KFLLGLKNNLPSTNV

MYO1A

786

Q9UBC5
PGLKFLDLNKNPLQR

LRRN2

261

O75325
FLLKSKILSPNGGKP

GLYAT

146

Q6IB77
PLPAKNLIFKDGVLS

FAM91A1

806

Q658Y4
LPSFPKNCTLELKGL

FREM1

2006

Q5H8C1
PKLFNSLLLGPTASN

KDM3B

1271

Q7LBC6
LPPASLGNLTLKGSK

KIAA2012

496

Q0VF49
PQAIKALPSLKELGF

LGR4

241

Q9BXB1
SLFKLKNQTAEPLAP

GOLGA6L3

136

A6NEY3
SLFKLKNQTAEPLAP

GOLGA6L4

136

A6NEF3
SLFKLKNQTAEPLAP

GOLGA6L9

136

A6NEM1
SLFKLKNQTAEPLAP

GOLGA6L10

136

A6NI86
SLFKLKNQTAEPLAP

GOLGA6L19

136

H0YKK7
LYSQKLPKGPSQALF

LILRB5

166

O75023
SLPSTQLKGFPLNLF

NDST4

171

Q9H3R1
AKNIPAFLPNVLSLK

KDM5A

981

P29375
NVNKLPELSSFGKPS

ARHGAP12

106

Q8IWW6
KKSTLPNPFHLGNLK

INTU

761

Q9ULD6
PSLLKKLLLAPANTQ

PPARGC1A

141

Q9UBK2
KANSNKSLPTPAVLL

PALLD

626

Q8WX93
QNLVPPGKKLSALQA

FRMPD4

391

Q14CM0
QYLQKFSPPLLGKGL

CYP4X1

111

Q8N118
LGKNLRQPKLSDLSP

DENND5B

711

Q6ZUT9
KALPGQLKPFETLLS

GSTP1

121

P09211
TPLNSISPLKKNFAS

CPEB4

326

Q17RY0
SELKKPLGPASFNLS

GDF9

326

O60383
TFLKKSGPSLNELIP

AHCTF1

501

Q8WYP5
KGCLPPLKLQASSNA

CCDC168

3751

Q8NDH2
LGKTQFSFPPLKIQD

CCDC168

4966

Q8NDH2
SLKPSKNFEILGQLP

FAM166A

91

Q6J272
IGKNNPPLKSRSFSL

OSBPL11

161

Q9BXB4
LGLSSNPKLQKPLFA

OR1L4

16

Q8NGR5
LLGLSSNPQLQKPLF

OR1L6

51

Q8NGR2
LNRPNYLSKLLGKLP

NR4A2

546

P43354
NKAKKQPLFGSLSPA

NUTM2E

816

B1AL46
STALIPGKKAPVLFN

NNT

316

Q13423
ALGSLFKQPSFPANK

RAB11FIP1

651

Q6WKZ4
NLQKPGFKSLKPTQL

TCAIM

71

Q8N3R3
GSAKQLPNAYFLLPK

TMEM131L

196

A2VDJ0
AFLKQLKNPIDSLPG

BMT2

221

Q1RMZ1
LNIKSAPSFNKLNPA

TDRD12

226

Q587J7
KNGQPLLFLSVPQIK

ODAD2

86

Q5T2S8
LLPGQSVTKSDFLPK

PPP1R32

231

Q7Z5V6
PPSVLQLNKKAGDLA

TNS3

1216

Q68CZ2
LNKPGLRFKPLTNQI

AKR1E2

181

Q96JD6
FLSNSLKKLVPFQLP

CHSY1

506

Q86X52
PPVKFLSTVLGKSNL

SHC4

241

Q6S5L8
AFLVKNLKPSPAVNL

STIL

1216

Q15468
NLKPSPAVNLRTGKA

STIL

1221

Q15468
TPASLPKFNLLLGKV

ZFHX2

1936

Q9C0A1
KNGSFTPRTANILKP

REV3L

1866

O60673
GSPKRIQSPLNNKLL

REV1

1081

Q9UBZ9
NNKLLNSPAKTLPGA

REV1

1091

Q9UBZ9
LPKALLSKNTAPDNG

TBL3

451

Q12788
NLFPGLSPSALKAKL

TNKS1BP1

1646

Q9C0C2
LLNPKGKPANQLLAL

PLAA

646

Q9Y263
LFPGSLLAEAQKNKP

SEC16B

201

Q96JE7
TLYNNLFGPKRPKAL

TRPM1

556

Q7Z4N2
APFKIPKTQASSNLL

ULK2

606

Q8IYT8
SLPGSLNPAFLKKSR

UBN1

11

Q9NPG3
LPGKSKQLIALASFP

WSCD2

336

Q2TBF2
PDIFLSGNKLVTLPK

TLR5

406

O60602
KPLSSLTFLNLLGNP

TLR2

121

O60603
PAAIGSQKKFSRPLL

PSD3

906

Q9NYI0