Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transporter activity	MFSD14A SLC6A7 ATP8B3 SLC6A13 ANO9 TMEM120B PIEZO2 NALCN KCNC2 ABCA5 SLC17A9 SLC31A2 ABCA12 KCNJ1 KCNJ4 HCN3 SLC22A10 TRPM2 STARD3 ABCC11 SLC28A3 TRPM8 TRPV3 OCA2 SLC33A1 SLC7A10 ABCA9 MFSD5 ANO8	9.75e-16	1289	76	29	GO:0005215
GeneOntologyMolecularFunction	transmembrane transporter activity	MFSD14A SLC6A7 SLC6A13 ANO9 TMEM120B PIEZO2 NALCN KCNC2 ABCA5 SLC17A9 SLC31A2 ABCA12 KCNJ1 KCNJ4 HCN3 SLC22A10 TRPM2 ABCC11 SLC28A3 TRPM8 TRPV3 OCA2 SLC33A1 SLC7A10 ABCA9 MFSD5 ANO8	8.78e-15	1180	76	27	GO:0022857
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC6A7 SLC6A13 ANO9 NALCN KCNC2 SLC31A2 KCNJ1 KCNJ4 HCN3 TRPM2 ABCC11 SLC28A3 TRPM8 TRPV3 OCA2 MFSD5 ANO8	2.77e-09	758	76	17	GO:0015318
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC6A7 SLC6A13 ANO9 TMEM120B PIEZO2 NALCN KCNC2 SLC31A2 KCNJ1 KCNJ4 HCN3 TRPM2 SLC28A3 TRPM8 TRPV3 OCA2 ANO8	5.44e-09	793	76	17	GO:0015075
GeneOntologyMolecularFunction	monoatomic ion channel activity	ANO9 TMEM120B PIEZO2 NALCN KCNC2 KCNJ1 KCNJ4 HCN3 TRPM2 TRPM8 TRPV3 OCA2 ANO8	1.73e-08	459	76	13	GO:0005216
GeneOntologyMolecularFunction	lipid transporter activity	ATP8B3 ANO9 ABCA5 ABCA12 SLC22A10 STARD3 ABCC11 ABCA9 ANO8	5.69e-08	196	76	9	GO:0005319
GeneOntologyMolecularFunction	channel activity	ANO9 TMEM120B PIEZO2 NALCN KCNC2 KCNJ1 KCNJ4 HCN3 TRPM2 TRPM8 TRPV3 OCA2 ANO8	8.32e-08	525	76	13	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	ANO9 TMEM120B PIEZO2 NALCN KCNC2 KCNJ1 KCNJ4 HCN3 TRPM2 TRPM8 TRPV3 OCA2 ANO8	8.51e-08	526	76	13	GO:0022803
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC6A7 SLC6A13 NALCN KCNC2 SLC31A2 KCNJ1 KCNJ4 HCN3 TRPM2 SLC28A3 TRPM8 TRPV3	1.78e-07	465	76	12	GO:0046873
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC6A7 SLC6A13 PIEZO2 NALCN KCNC2 SLC31A2 KCNJ1 KCNJ4 HCN3 TRPM2 SLC28A3 TRPM8 TRPV3	1.20e-06	664	76	13	GO:0008324
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC6A7 SLC6A13 NALCN KCNC2 SLC31A2 KCNJ1 KCNJ4 HCN3 TRPM2 SLC28A3 TRPM8 TRPV3	4.09e-06	627	76	12	GO:0022890
GeneOntologyMolecularFunction	gated channel activity	ANO9 PIEZO2 KCNC2 KCNJ1 KCNJ4 HCN3 TRPM2 TRPM8 ANO8	4.90e-06	334	76	9	GO:0022836
GeneOntologyMolecularFunction	monoatomic cation channel activity	PIEZO2 NALCN KCNC2 KCNJ1 KCNJ4 HCN3 TRPM2 TRPM8 TRPV3	6.07e-06	343	76	9	GO:0005261
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	ANO9 KCNJ1 KCNJ4 HCN3 TRPM2 TRPM8 ANO8	8.80e-06	193	76	7	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	ANO9 KCNJ1 KCNJ4 HCN3 TRPM2 TRPM8 ANO8	1.01e-05	197	76	7	GO:0022834
GeneOntologyMolecularFunction	G protein-coupled receptor activity	GPR19 GPR32 OR4D9 MRGPRX1 OR6C1 TAS1R1 P2RY13 LGR4 MRGPRX2 P2RY14 CASR TAS2R41 C5AR1	2.64e-05	884	76	13	GO:0004930
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA5 ABCA12 ABCC11 ABCA9	3.61e-05	49	76	4	GO:0140359
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ATP8B3 ANO9 ABCA12 ANO8	4.23e-05	51	76	4	GO:0140303
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	SLC6A13 ANO9 ABCC11 OCA2 MFSD5 ANO8	4.81e-05	171	76	6	GO:0015103
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC6A7 SLC6A13 NALCN HCN3 TRPM2 SLC28A3	4.81e-05	171	76	6	GO:0015081
GeneOntologyMolecularFunction	nucleobase-containing compound transmembrane transporter activity	SLC17A9 ABCC11 SLC28A3 SLC33A1	7.52e-05	59	76	4	GO:0015932
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC6A7 SLC6A13 ABCA5 SLC17A9 ABCA12 SLC22A10 ABCC11 SLC28A3 ABCA9	8.10e-05	477	76	9	GO:0022804
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC6A7 SLC6A13 SLC17A9 SLC22A10 ABCC11 SLC33A1 SLC7A10	1.25e-04	293	76	7	GO:0008514
GeneOntologyMolecularFunction	purine nucleotide transmembrane transporter activity	SLC17A9 ABCC11 SLC33A1	1.80e-04	29	76	3	GO:0015216
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	KCNJ1 KCNJ4 HCN3 TRPM2 TRPM8	1.95e-04	140	76	5	GO:0099094
GeneOntologyMolecularFunction	nucleotide transmembrane transporter activity	SLC17A9 ABCC11 SLC33A1	2.66e-04	33	76	3	GO:0015215
GeneOntologyMolecularFunction	organophosphate ester transmembrane transporter activity	SLC17A9 ABCC11 SLC33A1	4.39e-04	39	76	3	GO:0015605
GeneOntologyMolecularFunction	ATPase-coupled lipid transmembrane transporter activity	ABCA12 ABCC11	5.06e-04	9	76	2	GO:0034040
GeneOntologyMolecularFunction	voltage-gated potassium channel activity	KCNC2 KCNJ1 KCNJ4 HCN3	6.21e-04	102	76	4	GO:0005249
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA5 ABCA12 ABCC11 ABCA9	7.97e-04	109	76	4	GO:0042626
GeneOntologyMolecularFunction	sodium channel activity	NALCN HCN3 TRPM2	1.02e-03	52	76	3	GO:0005272
GeneOntologyMolecularFunction	G protein-coupled purinergic nucleotide receptor activity	P2RY13 P2RY14	1.09e-03	13	76	2	GO:0045028
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC6A7 SLC6A13 SLC22A10 ABCC11 SLC7A10	1.16e-03	207	76	5	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC6A7 SLC6A13 SLC22A10 ABCC11 SLC7A10	1.19e-03	208	76	5	GO:0005342
GeneOntologyMolecularFunction	complement receptor activity	GPR32 C5AR1	1.26e-03	14	76	2	GO:0004875
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	SLC6A13 ANO9 OCA2 ANO8	1.33e-03	125	76	4	GO:0015108
GeneOntologyMolecularFunction	potassium channel activity	KCNC2 KCNJ1 KCNJ4 HCN3	1.45e-03	128	76	4	GO:0005267
GeneOntologyMolecularFunction	carbohydrate derivative transmembrane transporter activity	SLC17A9 SLC28A3 SLC33A1	1.48e-03	59	76	3	GO:1901505
GeneOntologyMolecularFunction	sulfur compound transmembrane transporter activity	SLC6A13 ABCC11 SLC33A1	1.63e-03	61	76	3	GO:1901682
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	GPR32 MRGPRX1 LGR4 MRGPRX2	1.67e-03	133	76	4	GO:0008528
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	GPR19 GPR32 OR4D9 MRGPRX1 OR6C1 TAS1R1 P2RY13 LGR4 MRGPRX2 P2RY14 CASR TAS2R41 C5AR1	1.67e-03	1353	76	13	GO:0004888
GeneOntologyMolecularFunction	peptide receptor activity	GPR32 MRGPRX1 LGR4 MRGPRX2	2.01e-03	140	76	4	GO:0001653
GeneOntologyMolecularFunction	adenylate cyclase activity	ADCY2 ADCY3	2.10e-03	18	76	2	GO:0004016
GeneOntologyMolecularFunction	intracellularly calcium-gated channel activity	ANO9 ANO8	2.60e-03	20	76	2	GO:0141147
GeneOntologyMolecularFunction	intracellularly calcium-gated chloride channel activity	ANO9 ANO8	2.60e-03	20	76	2	GO:0005229
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	SLC6A13 ANO9 OCA2 ANO8	2.64e-03	151	76	4	GO:0008509
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	KCNC2 KCNJ1 KCNJ4 HCN3	2.71e-03	152	76	4	GO:0022843
GeneOntologyMolecularFunction	lipid transmembrane transporter activity	ABCA12 SLC22A10 ABCC11	2.72e-03	73	76	3	GO:0170055
GeneOntologyMolecularFunction	phospholipid transporter activity	ATP8B3 ANO9 ANO8	2.83e-03	74	76	3	GO:0005548
GeneOntologyMolecularFunction	glucosyltransferase activity	GYS1 ALG10	3.14e-03	22	76	2	GO:0046527
GeneOntologyMolecularFunction	protein-hormone receptor activity	LGR4 EXTL3	3.14e-03	22	76	2	GO:0016500
GeneOntologyMolecularFunction	nucleotide receptor activity	P2RY13 P2RY14	3.14e-03	22	76	2	GO:0016502
GeneOntologyMolecularFunction	purinergic nucleotide receptor activity	P2RY13 P2RY14	3.14e-03	22	76	2	GO:0001614
GeneOntologyMolecularFunction	purine ribonucleotide transmembrane transporter activity	SLC17A9 SLC33A1	3.43e-03	23	76	2	GO:0005346
GeneOntologyMolecularFunction	amino acid:sodium symporter activity	SLC6A7 SLC6A13	3.43e-03	23	76	2	GO:0005283
GeneOntologyMolecularFunction	phospholipid scramblase activity	ANO9 ANO8	3.43e-03	23	76	2	GO:0017128
GeneOntologyMolecularFunction	solute:sodium symporter activity	SLC6A7 SLC6A13 SLC28A3	3.65e-03	81	76	3	GO:0015370
GeneOntologyMolecularFunction	cyclase activity	ADCY2 ADCY3	3.74e-03	24	76	2	GO:0009975
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	KCNC2 KCNJ1 KCNJ4 HCN3	3.79e-03	167	76	4	GO:0015079
GeneOntologyMolecularFunction	phosphorus-oxygen lyase activity	ADCY2 ADCY3	4.05e-03	25	76	2	GO:0016849
GeneOntologyMolecularFunction	chloride channel activity	ANO9 OCA2 ANO8	4.32e-03	86	76	3	GO:0005254
GeneOntologyMolecularFunction	adenine nucleotide transmembrane transporter activity	SLC17A9 SLC33A1	4.38e-03	26	76	2	GO:0000295
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	NALCN HCN3	4.38e-03	26	76	2	GO:0005248
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ABCA5 ABCA12 ABCC11 ABCA9	4.76e-03	178	76	4	GO:0015399
GeneOntologyMolecularFunction	monocarboxylic acid transmembrane transporter activity	SLC6A13 SLC22A10 ABCC11	4.91e-03	90	76	3	GO:0008028
GeneOntologyMolecularFunction	inward rectifier potassium channel activity	KCNJ1 KCNJ4	5.07e-03	28	76	2	GO:0005242
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ATP8B3 ABCA12	5.07e-03	28	76	2	GO:0140326
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	KCNC2 KCNJ1 KCNJ4 HCN3	5.14e-03	182	76	4	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	KCNC2 KCNJ1 KCNJ4 HCN3	5.34e-03	184	76	4	GO:0022832
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC6A7 SLC6A13 SLC17A9 SLC22A10 SLC28A3	5.42e-03	296	76	5	GO:0015291
GeneOntologyMolecularFunction	amino acid:monoatomic cation symporter activity	SLC6A7 SLC6A13	5.43e-03	29	76	2	GO:0005416
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	TRPM2 TRPM8	6.19e-03	31	76	2	GO:0099604
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	HCN3 TRPM2	6.99e-03	33	76	2	GO:0005217
GeneOntologyMolecularFunction	taste receptor activity	TAS1R1 TAS2R41	6.99e-03	33	76	2	GO:0008527
GeneOntologyMolecularFunction	monoatomic anion channel activity	ANO9 OCA2 ANO8	7.13e-03	103	76	3	GO:0005253
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	SLC6A7 SLC6A13 SLC7A10	7.52e-03	105	76	3	GO:0015171
GeneOntologyMolecularFunction	organic acid:sodium symporter activity	SLC6A7 SLC6A13	7.84e-03	35	76	2	GO:0005343
GeneOntologyMolecularFunction	hexosyltransferase activity	DPY19L3 GYS1 ALG10 EXTL3	8.60e-03	211	76	4	GO:0016758
GeneOntologyMolecularFunction	neuropeptide binding	MRGPRX1 MRGPRX2	8.74e-03	37	76	2	GO:0042923
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC6A7 SLC6A13 SLC28A3	1.06e-02	119	76	3	GO:0015294
GeneOntologyMolecularFunction	neutral L-amino acid transmembrane transporter activity	SLC6A7 SLC7A10	1.07e-02	41	76	2	GO:0015175
GeneOntologyBiologicalProcess	monoatomic ion transport	SLC6A7 SLC6A13 ANO9 PIEZO2 NALCN KCNC2 SLC31A2 KCNJ1 KCNJ4 ALG10 HCN3 SLC22A10 TRPM2 ABCC11 SLC28A3 CASR TRPM8 TRPV3 OCA2 MFSD5 ANO8	8.46e-09	1374	74	21	GO:0006811
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	SLC6A7 SLC6A13 ANO9 PIEZO2 NALCN KCNC2 SLC31A2 KCNJ1 KCNJ4 ALG10 HCN3 TRPM2 ABCC11 SLC28A3 CASR TRPM8 TRPV3 OCA2 ANO8	9.05e-09	1115	74	19	GO:0034220
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	SLC6A7 SLC6A13 ANO9 NALCN KCNC2 SLC31A2 KCNJ1 KCNJ4 ALG10 HCN3 TRPM2 SLC28A3 CASR TRPM8 TRPV3 OCA2 ANO8	8.46e-08	1017	74	17	GO:0098660
GeneOntologyBiologicalProcess	chemosensory behavior	MRGPRX1 MRGPRX2 CASR ADCY3	4.46e-06	31	74	4	GO:0007635
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	SLC6A7 SLC6A13 PIEZO2 NALCN KCNC2 SLC31A2 KCNJ1 KCNJ4 ALG10 HCN3 TRPM2 SLC28A3 TRPM8 TRPV3	5.51e-06	942	74	14	GO:0098655
GeneOntologyBiologicalProcess	metal ion transport	SLC6A7 SLC6A13 NALCN KCNC2 SLC31A2 KCNJ1 KCNJ4 ALG10 HCN3 TRPM2 SLC28A3 CASR TRPM8 TRPV3	1.09e-05	1000	74	14	GO:0030001
GeneOntologyBiologicalProcess	monoatomic cation transport	SLC6A7 SLC6A13 PIEZO2 NALCN KCNC2 SLC31A2 KCNJ1 KCNJ4 ALG10 HCN3 TRPM2 SLC28A3 CASR TRPM8 TRPV3	1.25e-05	1157	74	15	GO:0006812
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	SLC6A7 SLC6A13 NALCN KCNC2 SLC31A2 KCNJ1 KCNJ4 ALG10 HCN3 TRPM2 SLC28A3 TRPM8 TRPV3	2.18e-05	922	74	13	GO:0098662
GeneOntologyBiologicalProcess	organophosphate ester transport	ATP8B3 ANO9 SLC17A9 ABCA12 ABCC11 SLC33A1	2.55e-05	162	74	6	GO:0015748
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	GPR19 GPR32 OR4D9 MRGPRX1 OR6C1 MRAP TAS1R1 P2RY13 LGR4 MRGPRX2 P2RY14 CASR TAS2R41 C5AR1 ADCY2 ADCY3	2.80e-05	1395	74	16	GO:0007186
GeneOntologyBiologicalProcess	sodium ion transport	SLC6A7 SLC6A13 NALCN KCNJ1 HCN3 TRPM2 SLC28A3	5.83e-05	275	74	7	GO:0006814
GeneOntologyBiologicalProcess	regulation of adenylate cyclase activity	P2RY13 LGR4 ADCY2 ADCY3	5.98e-05	59	74	4	GO:0045761
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	SLC6A7 SLC6A13 NALCN HCN3 TRPM2 SLC28A3	1.02e-04	208	74	6	GO:0035725
GeneOntologyBiologicalProcess	regulation of cyclase activity	P2RY13 LGR4 ADCY2 ADCY3	1.11e-04	69	74	4	GO:0031279
GeneOntologyBiologicalProcess	response to chloroquine	MRGPRX1 MRGPRX2	1.26e-04	5	74	2	GO:1902349
GeneOntologyBiologicalProcess	regulation of lyase activity	P2RY13 LGR4 ADCY2 ADCY3	1.38e-04	73	74	4	GO:0051339
GeneOntologyBiologicalProcess	import across plasma membrane	SLC6A7 SLC6A13 KCNJ1 KCNJ4 TRPM2 TRPV3	1.77e-04	230	74	6	GO:0098739
GeneOntologyBiologicalProcess	potassium ion transmembrane transport	NALCN KCNC2 KCNJ1 KCNJ4 ALG10 HCN3	1.86e-04	232	74	6	GO:0071805
GeneOntologyBiologicalProcess	monoatomic anion transmembrane transport	ANO9 ABCC11 CASR OCA2 ANO8	2.24e-04	153	74	5	GO:0098656
GeneOntologyBiologicalProcess	activation of adenylate cyclase activity	LGR4 ADCY2 ADCY3	2.45e-04	34	74	3	GO:0007190
GeneOntologyBiologicalProcess	purine-containing compound transmembrane transport	SLC17A9 SLC28A3 SLC33A1	3.98e-04	40	74	3	GO:0072530
GeneOntologyBiologicalProcess	positive regulation of adenylate cyclase activity	LGR4 ADCY2 ADCY3	3.98e-04	40	74	3	GO:0045762
GeneOntologyBiologicalProcess	potassium ion transport	NALCN KCNC2 KCNJ1 KCNJ4 ALG10 HCN3	4.35e-04	272	74	6	GO:0006813
GeneOntologyBiologicalProcess	inorganic anion transport	ANO9 CASR OCA2 MFSD5 ANO8	4.74e-04	180	74	5	GO:0015698
GeneOntologyBiologicalProcess	organic anion transport	SLC6A7 SLC6A13 SLC17A9 SLC22A10 ABCC11 CASR SLC33A1 SLC7A10	5.08e-04	515	74	8	GO:0015711
GeneOntologyBiologicalProcess	monoatomic anion transport	ANO9 ABCC11 CASR OCA2 ANO8	5.11e-04	183	74	5	GO:0006820
GeneOntologyBiologicalProcess	purine nucleotide transport	SLC17A9 ABCC11 SLC33A1	5.28e-04	44	74	3	GO:0015865
GeneOntologyBiologicalProcess	positive regulation of cyclase activity	LGR4 ADCY2 ADCY3	6.83e-04	48	74	3	GO:0031281
GeneOntologyBiologicalProcess	cAMP biosynthetic process	ADCY2 ADCY3	6.84e-04	11	74	2	GO:0006171
GeneOntologyBiologicalProcess	chloride transmembrane transport	ANO9 CASR OCA2 ANO8	7.08e-04	112	74	4	GO:1902476
GeneOntologyBiologicalProcess	positive regulation of lyase activity	LGR4 ADCY2 ADCY3	7.25e-04	49	74	3	GO:0051349
GeneOntologyBiologicalProcess	nucleotide transport	SLC17A9 ABCC11 SLC33A1	7.70e-04	50	74	3	GO:0006862
GeneOntologyBiologicalProcess	G protein-coupled purinergic nucleotide receptor signaling pathway	P2RY13 P2RY14	9.65e-04	13	74	2	GO:0035589
GeneOntologyCellularComponent	endoplasmic reticulum membrane	ATP8B3 DPY19L3 CEPT1 FADS3 DHCR7 MRAP ALG10 MARCHF6 RDH10 STARD3 SLC28A3 TRPM8 XK OCA2 EXTL3 SLC33A1 TMCC1	4.38e-06	1293	78	17	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	ATP8B3 DPY19L3 CEPT1 FADS3 DHCR7 MRAP ALG10 MARCHF6 RDH10 STARD3 SLC28A3 TRPM8 XK OCA2 EXTL3 SLC33A1 TMCC1	4.66e-06	1299	78	17	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	ATP8B3 DPY19L3 CEPT1 FADS3 DHCR7 MRAP ALG10 MARCHF6 RDH10 STARD3 SLC28A3 TRPM8 XK OCA2 EXTL3 SLC33A1 TMCC1	6.19e-06	1327	78	17	GO:0042175
GeneOntologyCellularComponent	endoplasmic reticulum-endosome membrane contact site	STARD3 TMCC1	8.21e-05	4	78	2	GO:0140284
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	SLC6A7 ATP8B3 ZDHHC11B ABCA5 SLC17A9 SLC31A2 ABCA12 KCNJ4 TRPM2 STARD3 ABCC11 OCA2 C5AR1 MCTP2 SYNGR4	8.43e-05	1307	78	15	GO:0030659
GeneOntologyCellularComponent	vesicle membrane	SLC6A7 ATP8B3 ZDHHC11B ABCA5 SLC17A9 SLC31A2 ABCA12 KCNJ4 TRPM2 STARD3 ABCC11 OCA2 C5AR1 MCTP2 SYNGR4	9.83e-05	1325	78	15	GO:0012506
GeneOntologyCellularComponent	neuronal cell body membrane	KCNC2 MRGPRX1 MRGPRX2	5.54e-04	43	78	3	GO:0032809
GeneOntologyCellularComponent	cell body membrane	KCNC2 MRGPRX1 MRGPRX2	7.20e-04	47	78	3	GO:0044298
GeneOntologyCellularComponent	basolateral plasma membrane	SLC6A13 KCNC2 KCNJ4 SLC22A10 CASR C5AR1	1.25e-03	320	78	6	GO:0016323
GeneOntologyCellularComponent	basal plasma membrane	SLC6A13 KCNC2 KCNJ4 SLC22A10 CASR C5AR1	2.09e-03	354	78	6	GO:0009925
GeneOntologyCellularComponent	vacuolar membrane	ABCA5 SLC17A9 SLC31A2 TRPM2 STARD3 ABCC11 OCA2	2.84e-03	507	78	7	GO:0005774
GeneOntologyCellularComponent	basal part of cell	SLC6A13 KCNC2 KCNJ4 SLC22A10 CASR C5AR1	2.89e-03	378	78	6	GO:0045178
GeneOntologyCellularComponent	voltage-gated potassium channel complex	KCNC2 KCNJ4 HCN3	4.80e-03	91	78	3	GO:0008076
GeneOntologyCellularComponent	transport vesicle membrane	SLC6A7 SLC17A9 ABCA12 MCTP2 SYNGR4	4.80e-03	293	78	5	GO:0030658
Domain	Ion_trans_dom	NALCN KCNC2 HCN3 TRPM2 TRPM8 TRPV3	6.47e-06	114	75	6	IPR005821
Domain	Ion_trans	NALCN KCNC2 HCN3 TRPM2 TRPM8 TRPV3	6.47e-06	114	75	6	PF00520
Domain	ABC_A	ABCA5 ABCA12 ABCA9	1.33e-05	12	75	3	IPR026082
Domain	ABC_TRANSPORTER_2	ABCA5 ABCA12 ABCC11 ABCA9	4.08e-05	48	75	4	PS50893
Domain	ABC_tran	ABCA5 ABCA12 ABCC11 ABCA9	4.08e-05	48	75	4	PF00005
Domain	ABC_TRANSPORTER_1	ABCA5 ABCA12 ABCC11 ABCA9	4.43e-05	49	75	4	PS00211
Domain	P2Y13_rcpt	P2RY13 P2RY14	4.76e-05	3	75	2	IPR008109
Domain	ABC_transporter-like	ABCA5 ABCA12 ABCC11 ABCA9	4.80e-05	50	75	4	IPR003439
Domain	DUF846	TVP23C TVP23B	9.50e-05	4	75	2	PF05832
Domain	DUF846_euk	TVP23C TVP23B	9.50e-05	4	75	2	IPR008564
Domain	MFS_dom	MFSD14A SLC17A9 SLC22A10 SLC33A1 MFSD5	2.04e-04	134	75	5	IPR020846
Domain	GPCR_Rhodpsn_7TM	GPR19 GPR32 OR4D9 MRGPRX1 OR6C1 P2RY13 LGR4 MRGPRX2 P2RY14 C5AR1	3.34e-04	670	75	10	IPR017452
Domain	7tm_1	GPR19 GPR32 OR4D9 MRGPRX1 OR6C1 P2RY13 LGR4 MRGPRX2 P2RY14 C5AR1	3.62e-04	677	75	10	PF00001
Domain	G_PROTEIN_RECEP_F1_1	GPR19 GPR32 OR4D9 MRGPRX1 OR6C1 P2RY13 LGR4 MRGPRX2 P2RY14 C5AR1	3.98e-04	685	75	10	PS00237
Domain	G_PROTEIN_RECEP_F1_2	GPR19 GPR32 OR4D9 MRGPRX1 OR6C1 P2RY13 LGR4 MRGPRX2 P2RY14 C5AR1	4.26e-04	691	75	10	PS50262
Domain	GPCR_Rhodpsn	GPR19 GPR32 OR4D9 MRGPRX1 OR6C1 P2RY13 LGR4 MRGPRX2 P2RY14 C5AR1	4.31e-04	692	75	10	IPR000276
Domain	AC_N	ADCY2 ADCY3	4.39e-04	8	75	2	IPR032628
Domain	Adcy	ADCY2 ADCY3	4.39e-04	8	75	2	IPR030672
Domain	AC_N	ADCY2 ADCY3	4.39e-04	8	75	2	PF16214
Domain	ABC_transporter_CS	ABCA5 ABCA12 ABCC11	6.38e-04	42	75	3	IPR017871
Domain	Anoctamin	ANO9 ANO8	7.01e-04	10	75	2	PF04547
Domain	Anoctamin	ANO9 ANO8	7.01e-04	10	75	2	IPR007632
Domain	Formyl_rcpt-rel	GPR32 C5AR1	7.01e-04	10	75	2	IPR000826
Domain	MRGPCRFAMILY	MRGPRX1 MRGPRX2	8.55e-04	11	75	2	IPR026234
Domain	MFS	MFSD14A SLC17A9 SLC22A10 MFSD5	9.37e-04	108	75	4	PS50850
Domain	NCD3G	TAS1R1 CASR	1.21e-03	13	75	2	PF07562
Domain	GPCR_3_9-Cys_dom	TAS1R1 CASR	1.21e-03	13	75	2	IPR011500
Domain	GPCR_3_CS	TAS1R1 CASR	1.40e-03	14	75	2	IPR017979
Domain	K_chnl_inward-rec_Kir_cyto	KCNJ1 KCNJ4	1.84e-03	16	75	2	IPR013518
Domain	IRK	KCNJ1 KCNJ4	1.84e-03	16	75	2	PF01007
Domain	-	KCNJ1 KCNJ4	1.84e-03	16	75	2	2.60.40.1400
Domain	K_chnl_inward-rec_Kir	KCNJ1 KCNJ4	1.84e-03	16	75	2	IPR016449
Domain	A/G_cyclase_CS	ADCY2 ADCY3	2.08e-03	17	75	2	IPR018297
Domain	Nucleotide_cyclase	ADCY2 ADCY3	2.34e-03	18	75	2	IPR029787
Domain	NA_NEUROTRAN_SYMP_2	SLC6A7 SLC6A13	2.34e-03	18	75	2	PS00754
Domain	-	ADCY2 ADCY3	2.34e-03	18	75	2	3.30.70.1230
Domain	GUANYLATE_CYCLASE_2	ADCY2 ADCY3	2.60e-03	19	75	2	PS50125
Domain	NA_NEUROTRAN_SYMP_3	SLC6A7 SLC6A13	2.60e-03	19	75	2	PS50267
Domain	GUANYLATE_CYCLASE_1	ADCY2 ADCY3	2.60e-03	19	75	2	PS00452
Domain	A/G_cyclase	ADCY2 ADCY3	2.60e-03	19	75	2	IPR001054
Domain	SNF	SLC6A7 SLC6A13	2.60e-03	19	75	2	PF00209
Domain	CYCc	ADCY2 ADCY3	2.60e-03	19	75	2	SM00044
Domain	Guanylate_cyc	ADCY2 ADCY3	2.60e-03	19	75	2	PF00211
Domain	Na/ntran_symport	SLC6A7 SLC6A13	2.60e-03	19	75	2	IPR000175
Domain	NA_NEUROTRAN_SYMP_1	SLC6A7 SLC6A13	2.60e-03	19	75	2	PS00610
Domain	AAA+_ATPase	ABCA5 ABCA12 ABCC11 ABCA9	2.70e-03	144	75	4	IPR003593
Domain	AAA	ABCA5 ABCA12 ABCC11 ABCA9	2.70e-03	144	75	4	SM00382
Domain	GPCR_3	TAS1R1 CASR	3.18e-03	21	75	2	IPR000337
Domain	G_PROTEIN_RECEP_F3_4	TAS1R1 CASR	3.49e-03	22	75	2	PS50259
Domain	7tm_3	TAS1R1 CASR	3.49e-03	22	75	2	PF00003
Domain	GPCR_3_C	TAS1R1 CASR	3.49e-03	22	75	2	IPR017978
Domain	G_PROTEIN_RECEP_F3_2	TAS1R1 CASR	3.49e-03	22	75	2	PS00980
Domain	G_PROTEIN_RECEP_F3_3	TAS1R1 CASR	3.49e-03	22	75	2	PS00981
Domain	G_PROTEIN_RECEP_F3_1	TAS1R1 CASR	3.49e-03	22	75	2	PS00979
Domain	MFS	MFSD14A SLC17A9 SLC22A10	3.68e-03	77	75	3	IPR011701
Domain	MFS_1	MFSD14A SLC17A9 SLC22A10	3.68e-03	77	75	3	PF07690
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC6A7 ATP8B3 SLC6A13 ANO9 NALCN ABCA5 ABCA12 TRPM2 ABCC11 SLC28A3 TRPM8 TRPV3 ADCY2 SLC33A1 SLC7A10 ADCY3 ABCA9 ANO8	1.58e-10	736	55	18	M27287
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC6A7 ATP8B3 SLC6A13 ANO9 NALCN ABCA5 ABCA12 TRPM2 SLC28A3 TRPM8 TRPV3 SLC33A1 SLC7A10 ABCA9 ANO8	3.06e-08	681	55	15	MM14985
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	ANO9 NALCN TRPM2 TRPM8 TRPV3 ANO8	2.26e-06	99	55	6	MM14910
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	ANO9 NALCN TRPM2 TRPM8 TRPV3 ANO8	3.37e-06	106	55	6	M27200
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP8B3 ANO9 NALCN TRPM2 TRPM8 TRPV3 ANO8	5.14e-06	176	55	7	MM15718
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP8B3 ANO9 NALCN TRPM2 TRPM8 TRPV3 ANO8	6.64e-06	183	55	7	M997
Pathway	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	TAS1R1 P2RY13 P2RY14 CASR TAS2R41 C5AR1 ADCY2 ADCY3	1.49e-05	289	55	8	MM15057
Pathway	KEGG_ABC_TRANSPORTERS	ABCA5 ABCA12 ABCC11 ABCA9	2.51e-05	44	55	4	M11911
Pathway	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	TAS1R1 P2RY13 P2RY14 CASR TAS2R41 C5AR1 ADCY2 ADCY3	2.71e-05	314	55	8	M600
Pathway	REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	ABCA5 ABCA12 ABCA9	3.68e-05	17	55	3	MM14552
Pathway	REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	ABCA5 ABCA12 ABCA9	4.40e-05	18	55	3	M524
Pathway	REACTOME_TRP_CHANNELS	TRPM2 TRPM8 TRPV3	1.72e-04	28	55	3	MM14943
Pathway	REACTOME_TRP_CHANNELS	TRPM2 TRPM8 TRPV3	1.72e-04	28	55	3	M27241
Pathway	KEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY	MRAP ADCY2 ADCY3	2.34e-04	31	55	3	M47507
Pathway	KEGG_MEDICUS_REFERENCE_ACTH_CORTISOL_SIGNALING_PATHWAY	MRAP ADCY2 ADCY3	2.57e-04	32	55	3	M47506
Pathway	REACTOME_NEURONAL_SYSTEM	SLC6A13 KCNC2 KCNJ1 KCNJ4 HCN3 ADCY2 ADCY3	3.06e-04	335	55	7	MM14503
Pathway	REACTOME_SIGNALING_BY_GPCR	GPR32 TAS1R1 P2RY13 P2RY14 CASR XK TAS2R41 C5AR1 ADCY2 ADCY3	3.36e-04	702	55	10	M746
Pathway	WP_GPCRS_ODORANT	GPR19 MRGPRX1 TAS1R1 LGR4 MRGPRX2	3.57e-04	157	55	5	MM15872
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	TAS1R1 CASR TAS2R41	3.98e-04	37	55	3	MM15067
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	TAS1R1 CASR TAS2R41	4.65e-04	39	55	3	M793
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNC2 KCNJ1 KCNJ4 HCN3	5.71e-04	98	55	4	MM14545
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	KCNJ4 ADCY2 ADCY3	6.21e-04	43	55	3	M954
Pathway	REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY	ADCY2 ADCY3	6.59e-04	10	55	2	M19522
Pathway	REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY	ADCY2 ADCY3	6.59e-04	10	55	2	MM14668
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	KCNJ4 ADCY2 ADCY3	6.65e-04	44	55	3	MM15709
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNC2 KCNJ1 KCNJ4 HCN3	6.89e-04	103	55	4	M1073
Pathway	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	ABCA5 ABCA12 ABCC11 ABCA9	6.89e-04	103	55	4	M758
Pathway	REACTOME_P2Y_RECEPTORS	P2RY13 P2RY14	8.04e-04	11	55	2	MM15049
Pathway	REACTOME_SIGNALING_BY_GPCR	TAS1R1 P2RY13 P2RY14 CASR XK TAS2R41 C5AR1 ADCY2 ADCY3	8.09e-04	646	55	9	MM14962
Pathway	REACTOME_P2Y_RECEPTORS	P2RY13 P2RY14	9.62e-04	12	55	2	M10960
Pathway	REACTOME_NEURONAL_SYSTEM	SLC6A13 KCNC2 KCNJ1 KCNJ4 HCN3 ADCY2 ADCY3	1.03e-03	411	55	7	M735
Pathway	REACTOME_INDUCTION_OF_CELL_CELL_FUSION	ANO9 ANO8	1.13e-03	13	55	2	M46426
Pathway	REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY	ADCY2 ADCY3	1.32e-03	14	55	2	MM14669
Pathway	REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY	ADCY2 ADCY3	1.32e-03	14	55	2	M750
Pathway	REACTOME_GPCR_LIGAND_BINDING	TAS1R1 P2RY13 P2RY14 CASR XK TAS2R41 C5AR1	1.34e-03	430	55	7	MM15160
Pathway	KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY	ADCY2 ADCY3	1.52e-03	15	55	2	M47794
Pathway	PID_LPA4_PATHWAY	ADCY2 ADCY3	1.52e-03	15	55	2	M56
Pathway	KEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY	ADCY2 ADCY3	1.52e-03	15	55	2	M47504
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	KCNJ4 ADCY2 ADCY3	1.64e-03	60	55	3	M976
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	KCNJ4 ADCY2 ADCY3	1.64e-03	60	55	3	MM15708
Pathway	REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS	P2RY13 P2RY14	1.73e-03	16	55	2	M6786
Pathway	REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS	P2RY13 P2RY14	1.73e-03	16	55	2	MM15050
Pathway	WP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE	ADCY2 ADCY3	1.73e-03	16	55	2	M39849
Pathway	KEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY	ADCY2 ADCY3	1.73e-03	16	55	2	M47645
Pathway	KEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY	ADCY2 ADCY3	1.73e-03	16	55	2	M47650
Pathway	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	ADCY2 ADCY3	1.73e-03	16	55	2	MM14492
Pathway	REACTOME_PKA_ACTIVATION_IN_GLUCAGON_SIGNALLING	ADCY2 ADCY3	1.96e-03	17	55	2	M26995
Pathway	KEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY	ADCY2 ADCY3	1.96e-03	17	55	2	M47544
Pathway	REACTOME_GPCR_LIGAND_BINDING	TAS1R1 P2RY13 P2RY14 CASR XK TAS2R41 C5AR1	2.05e-03	463	55	7	M507
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC6A7 SLC6A13 SLC28A3 SLC33A1 SLC7A10	2.30e-03	238	55	5	MM15076
Pathway	REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS	SLC6A7 SLC6A13	2.45e-03	19	55	2	M27362
Pathway	REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS	SLC6A7 SLC6A13	2.45e-03	19	55	2	MM15107
Pathway	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	ADCY2 ADCY3	2.71e-03	20	55	2	M759
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC6A7 SLC6A13 SLC28A3 SLC33A1 SLC7A10	2.80e-03	249	55	5	M5988
Pathway	WP_GPCRS_NONODORANT	P2RY13 P2RY14 CASR TAS2R41 C5AR1	3.71e-03	266	55	5	MM15843
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY	ADCY2 ADCY3	3.90e-03	24	55	2	M47520
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY	ADCY2 ADCY3	4.57e-03	26	55	2	M47553
Pathway	REACTOME_CA_DEPENDENT_EVENTS	ADCY2 ADCY3	4.57e-03	26	55	2	MM14495
Pathway	KEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY	ADCY2 ADCY3	4.93e-03	27	55	2	M47518
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY	ADCY2 ADCY3	4.93e-03	27	55	2	M47519
Pathway	KEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY	ADCY2 ADCY3	5.29e-03	28	55	2	M47647
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY	ADCY2 ADCY3	5.67e-03	29	55	2	M47515
Pathway	KEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY	ADCY2 ADCY3	5.67e-03	29	55	2	M47627
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	GPR19 P2RY13 P2RY14 C5AR1	5.93e-03	186	55	4	MM15994
Pathway	REACTOME_SENSORY_PERCEPTION_OF_TASTE	TAS1R1 TAS2R41	6.46e-03	31	55	2	MM15691
Pathway	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	ABCA5 ABCA12 ABCA9	6.77e-03	99	55	3	MM14986
Pathway	WP_PURINERGIC_SIGNALING	P2RY13 P2RY14	7.30e-03	33	55	2	M39855
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	ADCY2 ADCY3	7.30e-03	33	55	2	MM15058
Pathway	REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION	ADCY2 ADCY3	7.30e-03	33	55	2	M11575
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	KCNJ1 KCNJ4	8.19e-03	35	55	2	M1075
Pathway	KEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY	ADCY2 ADCY3	8.19e-03	35	55	2	M47969
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	KCNC2 ADCY2 ADCY3	8.59e-03	108	55	3	M17034
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	KCNJ1 KCNJ4	8.65e-03	36	55	2	MM14544
Pathway	REACTOME_CA_DEPENDENT_EVENTS	ADCY2 ADCY3	9.12e-03	37	55	2	M749
Pathway	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES	SLC6A13 KCNJ4 ADCY2 ADCY3	9.17e-03	211	55	4	MM14502
Pubmed	The human ATP-binding cassette (ABC) transporter superfamily.	ABCA5 ABCA12 ABCC11 ABCA9	4.86e-09	10	78	4	11435397
Pubmed	C-LTMRs mediate wet dog shakes via the spinoparabrachial pathway.	PIEZO2 MRGPRX1 MRGPRX2 TRPM8	8.84e-08	19	78	4	38915692
Pubmed	Involvement of TRPM2 and TRPM8 in temperature-dependent masking behavior.	TRPM2 TRPM8 TRPV3	1.08e-07	5	78	3	30842533
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	MFSD14A SHLD2 ANO9 FADS3 SLC17A9 KCNJ1 TMEM254 PHTF2 LGR4 P2RY14 SLC33A1 ADCY3 TMEM181	8.23e-07	1084	78	13	11544199
Pubmed	DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon.	PIEZO2 MRGPRX1 MRGPRX2	4.84e-06	15	78	3	37541195
Pubmed	The transmembrane segment S6 determines cation versus anion selectivity of TRPM2 and TRPM8.	TRPM2 TRPM8	4.97e-06	2	78	2	17604279
Pubmed	Mas-Related G-Protein Coupled Receptors and Cowhage-Induced Itch.	MRGPRX1 MRGPRX2	4.97e-06	2	78	2	28988117
Pubmed	Importance of a conserved sequence motif in transmembrane segment S3 for the gating of human TRPM8 and TRPM2.	TRPM2 TRPM8	4.97e-06	2	78	2	23185472
Pubmed	Contribution of the S5-pore-S6 domain to the gating characteristics of the cation channels TRPM2 and TRPM8.	TRPM2 TRPM8	4.97e-06	2	78	2	20587417
Pubmed	Incoherent feed-forward regulatory loops control segregation of C-mechanoreceptors, nociceptors, and pruriceptors.	MRGPRX1 MRGPRX2 TRPM8	7.21e-06	17	78	3	25834056
Pubmed	Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia.	TRPM2 TRPM8 TRPV3	8.64e-06	18	78	3	31911949
Pubmed	Tlx3 and Runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors.	MRGPRX1 MRGPRX2 TRPM8	1.02e-05	19	78	3	22787056
Pubmed	Uncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptor.	MRGPRX1 MRGPRX2 TRPM8	1.02e-05	19	78	3	24516396
Pubmed	ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons.	MRGPRX1 MRGPRX2 TRPM8	1.40e-05	21	78	3	25369838
Pubmed	Molecular Sensors of Temperature, Pressure, and Pain with Special Focus on TRPV1, TRPM8, and PIEZO2 Ion Channels.	PIEZO2 TRPM8	1.49e-05	3	78	2	34825354
Pubmed	Gi- and Gq-coupled ADP (P2Y) receptors act in opposition to modulate nociceptive signaling and inflammatory pain behavior.	P2RY13 P2RY14	1.49e-05	3	78	2	20398327
Pubmed	Involvement of TRPV3 and TRPM8 ion channel proteins in induction of mammalian cold-inducible proteins.	TRPM8 TRPV3	1.49e-05	3	78	2	29175331
Pubmed	Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.	ABCA5 ABCA12 ABCA9	1.62e-05	22	78	3	8894702
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	SLC6A7 SLC6A13 KCNJ1 KCNJ4 CASR	1.82e-05	143	78	5	20424473
Pubmed	Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation.	MRGPRX1 MRGPRX2 TRPM8	1.86e-05	23	78	3	20096094
Pubmed	Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain.	MRGPRX1 MRGPRX2 TRPM8	1.86e-05	23	78	3	16446141
Pubmed	Mapping the expression of transient receptor potential channels across murine placental development.	TRPM2 TRPM8 TRPV3	2.12e-05	24	78	3	33884443
Pubmed	A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons.	MRGPRX1 MRGPRX2 TRPM8	2.12e-05	24	78	3	17553423
Pubmed	International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.	TRPM2 TRPM8 TRPV3	2.41e-05	25	78	3	16382100
Pubmed	Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy.	TRPM8 TRPV3	2.97e-05	4	78	2	17521436
Pubmed	Cloning and functional expression of a novel Gi protein-coupled receptor for adenine from mouse brain.	MRGPRX1 MRGPRX2	2.97e-05	4	78	2	17975009
Pubmed	Characterization of new G protein-coupled adenine receptors in mouse and hamster.	MRGPRX1 MRGPRX2	2.97e-05	4	78	2	23608776
Pubmed	Voltage-gated potassium channels involved in regulation of physiological function in MrgprA3-specific itch neurons.	MRGPRX1 MRGPRX2	2.97e-05	4	78	2	26874069
Pubmed	Acute digoxin loading reduces ABCA8A mRNA expression in the mouse liver.	ABCA5 ABCA9	2.97e-05	4	78	2	16445568
Pubmed	MrgprA3 shows sensitization to chloroquine in an acetone-ether-water mice model.	MRGPRX1 MRGPRX2	2.97e-05	4	78	2	29064954
Pubmed	Low maternal care enhances the skin barrier resistance of offspring in mice.	MRGPRX1 MRGPRX2	2.97e-05	4	78	2	31295326
Pubmed	Activation of MrgprA3 and MrgprC11 on Bladder-Innervating Afferents Induces Peripheral and Central Hypersensitivity to Bladder Distension.	MRGPRX1 MRGPRX2	2.97e-05	4	78	2	33727332
Pubmed	A mechanically activated ion channel is functionally expressed in the MrgprB4 positive sensory neurons, which detect stroking of hairy skin in mice.	MRGPRX1 MRGPRX2	2.97e-05	4	78	2	28545921
Pubmed	CFTR and TMEM16A are separate but functionally related Cl- channels.	ANO9 ANO8	2.97e-05	4	78	2	22178883
Pubmed	Substance P activates Mas-related G protein-coupled receptors to induce itch.	MRGPRX1 MRGPRX2	2.97e-05	4	78	2	28219706
Pubmed	Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection.	MRGPRX1 MRGPRX2	2.97e-05	4	78	2	35882236
Pubmed	Molecular Signature of Pruriceptive MrgprA3+ Neurons.	MRGPRX1 MRGPRX2	2.97e-05	4	78	2	32234460
Pubmed	An introduction to TRP channels.	TRPM2 TRPM8 TRPV3	3.05e-05	27	78	3	16460286
Pubmed	Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-beta signaling.	MRGPRX1 MRGPRX2 TRPM8	4.66e-05	31	78	3	21300867
Pubmed	2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3.	TRPM8 TRPV3	4.94e-05	5	78	2	15194687
Pubmed	Mammalian adenylyl cyclase family members are randomly located on different chromosomes.	ADCY2 ADCY3	4.94e-05	5	78	2	7959689
Pubmed	Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus.	MRGPRX1 MRGPRX2	4.94e-05	5	78	2	20004959
Pubmed	Hippocampal short- and long-term plasticity are not modulated by astrocyte Ca2+ signaling.	MRGPRX1 MRGPRX2	4.94e-05	5	78	2	20203048
Pubmed	Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch.	MRGPRX1 MRGPRX2	4.94e-05	5	78	2	17618277
Pubmed	Regional Differences in Itch Transmission.	MRGPRX1 MRGPRX2	4.94e-05	5	78	2	38735364
Pubmed	Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.	ABCA5 ABCA9	4.94e-05	5	78	2	12532264
Pubmed	An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors.	P2RY13 P2RY14	4.94e-05	5	78	2	11273702
Pubmed	MrgprB4 in trigeminal neurons expressing TRPA1 modulates unpleasant sensations.	MRGPRX1 MRGPRX2	4.94e-05	5	78	2	34116733
Pubmed	Common variants in genes underlying monogenic hypertension and hypotension and blood pressure in the general population.	KCNJ1 CASR	4.94e-05	5	78	2	18443236
Pubmed	Astrocytes modulate neural network activity by Ca²+-dependent uptake of extracellular K+.	MRGPRX1 MRGPRX2	4.94e-05	5	78	2	22472648
Pubmed	Cross-sensitization of histamine-independent itch in mouse primary sensory neurons.	MRGPRX1 MRGPRX2	4.94e-05	5	78	2	23000623
Pubmed	The Sensory Coding of Warm Perception.	TRPM2 TRPM8	4.94e-05	5	78	2	32208171
Pubmed	Structure of the GOLD-domain seven-transmembrane helix protein family member TMEM87A.	TMEM87B TMEM181	4.94e-05	5	78	2	36373655
Pubmed	Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress.	TRPM2 TRPM8 TRPV3	5.64e-05	33	78	3	30037926
Pubmed	A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.	TRPM2 TRPM8 TRPV3	5.64e-05	33	78	3	19834762
Pubmed	Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo.	MRGPRX1 MRGPRX2	7.40e-05	6	78	2	23364746
Pubmed	A subpopulation of nociceptors specifically linked to itch.	MRGPRX1 MRGPRX2	7.40e-05	6	78	2	23263443
Pubmed	Mapping of adenylyl cyclase genes type I, II, III, IV, V, and VI in mouse.	ADCY2 ADCY3	7.40e-05	6	78	2	7766992
Pubmed	Identification of a bilirubin receptor that may mediate a component of cholestatic itch.	MRGPRX1 MRGPRX2	7.40e-05	6	78	2	30657454
Pubmed	Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland.	ADCY2 ADCY3	7.40e-05	6	78	2	11549699
Pubmed	Enhanced excitability of MRGPRA3- and MRGPRD-positive nociceptors in a model of inflammatory itch and pain.	MRGPRX1 MRGPRX2	7.40e-05	6	78	2	24549959
Pubmed	Visualizing the Itch-Sensing Skin Arbors.	MRGPRX1 MRGPRX2	7.40e-05	6	78	2	33091423
Pubmed	Touch neurons underlying dopaminergic pleasurable touch and sexual receptivity.	MRGPRX1 MRGPRX2	1.04e-04	7	78	2	36693373
Pubmed	Differential expression of adenylyl cyclase mRNAs in lacrimal glands of NZB/NZW and NOD pre-autoimmune mice.	ADCY2 ADCY3	1.04e-04	7	78	2	12613887
Pubmed	Proinflammatory mediators modulate the heat-activated ion channel TRPV1 via the scaffolding protein AKAP79/150.	TRPM8 TRPV3	1.04e-04	7	78	2	18701070
Pubmed	Adenosine A2A Receptors Contribute to the Radial Migration of Cortical Projection Neurons through the Regulation of Neuronal Polarization and Axon Formation.	SLC17A9 NT5E	1.04e-04	7	78	2	34184030
Pubmed	Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.	TRPM2 TRPM8 TRPV3	1.35e-04	44	78	3	19322198
Pubmed	Expression of TMEM16 paralogs during murine embryogenesis.	ANO9 ANO8	1.38e-04	8	78	2	18729231
Pubmed	The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels.	ANO9 ANO8	1.38e-04	8	78	2	21984732
Pubmed	Anoctamins are a family of Ca2+-activated Cl- channels.	ANO9 ANO8	1.38e-04	8	78	2	22946059
Pubmed	Expression and function of epithelial anoctamins.	ANO9 ANO8	1.38e-04	8	78	2	20056604
Pubmed	Comparative genomic analysis of eutherian Mas-related G protein-coupled receptor genes.	MRGPRX1 MRGPRX2	1.38e-04	8	78	2	24583173
Pubmed	Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.	MRGPRX1 MRGPRX2	1.38e-04	8	78	2	12909716
Pubmed	Identification of G protein-coupled receptor genes from the human genome sequence.	MRGPRX1 P2RY13 MRGPRX2	1.54e-04	46	78	3	12044878
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	MFSD14A SLC31A2 KCNJ4 MRAP MARCHF6 ADCY2 KIAA2013 ANO8	1.71e-04	697	78	8	28298427
Pubmed	Diverse Targets of β-Catenin during the Epithelial-Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse.	ABCA5 ABCC11	1.77e-04	9	78	2	26122848
Pubmed	Role of the calcium modulated cyclases in the development of the retinal projections.	ADCY2 ADCY3	1.77e-04	9	78	2	17229090
Pubmed	Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.	ADCY2 ADCY3	1.77e-04	9	78	2	9417641
Pubmed	Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.	ADCY2 ADCY3	1.77e-04	9	78	2	12503609
Pubmed	Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway.	MRGPRX1 MRGPRX2	1.77e-04	9	78	2	12397184
Pubmed	Multiplexed peroxidase-based electron microscopy labeling enables simultaneous visualization of multiple cell types.	MRGPRX1 MRGPRX2	1.77e-04	9	78	2	30886406
Pubmed	The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids.	TAS1R1 CASR	2.21e-04	10	78	2	17156446
Pubmed	Anoctamin/TMEM16 family members are Ca2+-activated Cl- channels.	ANO9 ANO8	2.21e-04	10	78	2	19015192
Pubmed	Purification and characterization of a soluble form of mammalian adenylyl cyclase.	ADCY2 ADCY3	2.21e-04	10	78	2	8663304
Pubmed	Mechanism of human immunodeficiency virus-induced complement expression in astrocytes and neurons.	ADCY2 ADCY3	2.21e-04	10	78	2	11884542
Pubmed	Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members.	ANO9 ANO8	2.21e-04	10	78	2	23532839
Pubmed	Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain.	ADCY2 ADCY3	2.21e-04	10	78	2	16615126
Pubmed	Structure and function of TMEM16 proteins (anoctamins).	ANO9 ANO8	2.21e-04	10	78	2	24692353
Pubmed	Expression of olfactory receptors in the cribriform mesenchyme during prenatal development.	OR6C1 ADCY3	2.21e-04	10	78	2	15261832
Pubmed	Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens.	MRGPRX1 MRGPRX2	2.21e-04	10	78	2	33098765
Pubmed	A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons.	MRGPRX1 MRGPRX2	2.70e-04	11	78	2	11551509
Pubmed	Involvement of adenylate cyclase and p70(S6)-kinase activation in IL-10 up-regulation in human monocytes by gp41 envelope protein of human immunodeficiency virus type 1.	ADCY2 ADCY3	2.70e-04	11	78	2	10089566
Pubmed	gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression.	ADCY2 ADCY3	2.70e-04	11	78	2	10808179
Pubmed	Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures.	ADCY2 ADCY3	2.70e-04	11	78	2	11299302
Pubmed	An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates.	MRGPRX1 MRGPRX2	2.70e-04	11	78	2	21151121
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	KCNC2 KCNJ1 KCNJ4 HCN3	2.77e-04	139	78	4	16985003
Pubmed	Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons.	TRPM2 TRPM8	3.23e-04	12	78	2	19850157
Pubmed	HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones.	ADCY2 ADCY3	3.23e-04	12	78	2	10807185
Pubmed	Isoforms of mammalian adenylyl cyclase: multiplicities of signaling.	ADCY2 ADCY3	4.44e-04	14	78	2	14993377
Pubmed	Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.	SLC6A13 FADS3	4.44e-04	14	78	2	23378610
Interaction	LPAR1 interactions	TMEM120B TNFSF18 TMEM87B ALG10 EXTL3 MFSD5 KIAA2013	1.10e-05	210	73	7	int:LPAR1
Interaction	TTYH1 interactions	DPY19L3 TMEM120B ALG10 HCN3 STARD3 TVP23C PHTF2 ADCY3	1.28e-05	300	73	8	int:TTYH1
Interaction	SPPL2B interactions	TXNDC15 ALG10 TVP23C EXTL3 MFSD5 TMEM181 KIAA2013	2.15e-05	233	73	7	int:SPPL2B
Interaction	ENTPD7 interactions	TMEM120B TMEM87B SLC33A1 TMEM181	4.06e-05	53	73	4	int:ENTPD7
Interaction	TSPAN15 interactions	TMEM120B ALG10 TVP23C LGR4 EXTL3 TMEM181 KIAA2013	6.31e-05	276	73	7	int:TSPAN15
Interaction	VIPR1 interactions	TMEM87B STARD3 TVP23C SLC33A1 MFSD5 KIAA2013	9.94e-05	205	73	6	int:VIPR1
GeneFamily	G protein-coupled receptors, Class A orphans	GPR19 GPR32 MRGPRX1 LGR4 MRGPRX2	3.52e-06	78	54	5	262
GeneFamily	ATP binding cassette subfamily A	ABCA5 ABCA12 ABCA9	8.96e-06	14	54	3	805
GeneFamily	Solute carriers	SLC6A7 SLC6A13 SLC17A9 SLC31A2 SLC22A10 SLC28A3 SLC33A1 SLC7A10	2.09e-05	395	54	8	752
GeneFamily	Transient receptor potential cation channels	TRPM2 TRPM8 TRPV3	7.83e-05	28	54	3	249
GeneFamily	Adenylate cyclases\|Deafness associated genes	ADCY2 ADCY3	3.88e-04	10	54	2	53
GeneFamily	Purinergic receptors P2Y	P2RY13 P2RY14	3.88e-04	10	54	2	213
GeneFamily	Anoctamins	ANO9 ANO8	3.88e-04	10	54	2	865
GeneFamily	Potassium voltage-gated channel subfamily J	KCNJ1 KCNJ4	1.02e-03	16	54	2	276
ToppCell	droplet-Lung-3m-Hematologic-myeloid-neutrophil-neutrophil\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A13 TRPM2 P2RY13 C5AR1 TMCC1	7.36e-06	153	78	5	ce6e462ce4dbaf9d265f1f9e2f791efbba8c1dd0
ToppCell	droplet-Lung-3m-Hematologic-myeloid-neutrophil\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A13 TRPM2 P2RY13 C5AR1 TMCC1	7.36e-06	153	78	5	9dba38574908f31a1194b8a339868f5e4be1be71
ToppCell	droplet-Lung-nan-3m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A13 TRPM2 P2RY13 C5AR1 TMCC1	8.34e-06	157	78	5	3cffedafff31efb5b3259194157b54a768367459
ToppCell	droplet-Lung-nan-3m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A13 TRPM2 P2RY13 C5AR1 TMCC1	8.34e-06	157	78	5	f87e867a394b0453ebd92c592e80450caf5902cb
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A13 TRPM2 C5AR1 ADTRP MCTP2	8.34e-06	157	78	5	320d5ac063fd90e26f537475c328b3ae73974bc1
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid-mast_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A13 TRPM2 C5AR1 ADTRP MCTP2	8.34e-06	157	78	5	e4b17c267b754c5af95cdf17f629354d1a8a8ad7
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-cDC2\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC31A2 TRPM2 TVP23C P2RY13 P2RY14	1.13e-05	167	78	5	1bd0aa7a3c8649f342bb856cf861c4c5984ad889
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 P2RY13 ADCY3 ABCA9 ANO8	1.16e-05	168	78	5	04e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCell	facs-Skin-Anagen-3m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEPT1 SLC31A2 ABCA12 ADTRP MFSD5	1.57e-05	179	78	5	4a072526c3a524a7aed99bdb32a07a1ce1f48972
ToppCell	facs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 ABCA5 P2RY13 P2RY14 MCTP2	1.62e-05	180	78	5	bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCell	facs-Marrow-B-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 ABCA5 P2RY13 P2RY14 MCTP2	1.62e-05	180	78	5	839defb40f7cfb2711e9025194de636533f51bcd
ToppCell	facs-Marrow-B-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 ABCA5 P2RY13 P2RY14 MCTP2	1.62e-05	180	78	5	82965ed1b72a1873c24dd4553d39681596057316
ToppCell	Immune_cells-Dendritic_cells\|Immune_cells / Lineage and Cell class	FADS3 ABCA5 P2RY13 P2RY14 MCTP2	1.70e-05	182	78	5	99c7d4f1e7cd745643ba64b59190113bcd4e348e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 KCNJ1 LGR4 CASR ABCA9	1.94e-05	187	78	5	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 KCNJ1 LGR4 CASR ABCA9	1.94e-05	187	78	5	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	ABCA5 KCNJ1 LGR4 CASR ABCA9	1.99e-05	188	78	5	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	medial-2-Hematologic-IGSF21+_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KCNJ1 P2RY13 P2RY14 C5AR1 ADCY2	2.37e-05	195	78	5	bb612979360b2322289545dda3d3c343d005ee6f
ToppCell	medial-Hematologic-IGSF21+_Dendritic-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KCNJ1 P2RY13 P2RY14 C5AR1 ADCY2	2.37e-05	195	78	5	779130c2cfcbc603955b0c0332b855b22ab6e9e6
ToppCell	medial-Hematologic-IGSF21+_Dendritic\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KCNJ1 P2RY13 P2RY14 C5AR1 ADCY2	2.37e-05	195	78	5	330b688d703d53cb7feb29373b5a6e6e529169ec
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NT5E TRPM2 C5AR1 TMCC1	8.79e-05	133	78	4	f6e9a1301a3379847b215303a9b0c028841e2cc0
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NT5E TRPM2 C5AR1 TMCC1	8.79e-05	133	78	4	292ecfcadbaf15e0d34a3ab9bf511ab1065888bd
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 TRPV3 OCA2 C5AR1	1.04e-04	139	78	4	27dd36f5ef03fa97f0fdb19fbd259cb60e7962b3
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 TRPV3 OCA2 C5AR1	1.04e-04	139	78	4	2a54627947f8c6597c041f4785f8a4e52d0edfba
ToppCell	PND07-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC6A13 TRPM2 C5AR1 ADTRP	1.07e-04	140	78	4	90298cac4bcec614a48e60b5c139c86daa9f0321
ToppCell	PND07-Immune-Immune_Myeloid-Granulocytic-Neutrophil\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC6A13 TRPM2 C5AR1 ADTRP	1.07e-04	140	78	4	671ab1f5cbd8568bf93ebdf961c2a1ede06d2bcb
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	SLC6A7 TMEM120B TVP23C ADTRP	1.47e-04	152	78	4	7a1072315cce71eefe2d32149a107d5648999968
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRAP TRPM2 P2RY13 ABCA9	1.62e-04	156	78	4	d72c2f5f72d269e29033f8728d924e0d4c8772c7
ToppCell	droplet-Lung-LUNG-1m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A13 TRPM2 C5AR1 TMCC1	1.71e-04	158	78	4	30cceb73cf5e24b692da84d33342fd3b1ad5efe5
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A13 TRPM2 C5AR1 TMCC1	1.71e-04	158	78	4	47793463640f98ee5f680a1ee5786b453355fd57
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	GPR19 PHTF2 ADTRP ADCY2	1.75e-04	159	78	4	ae53ab7a1339007d0b245c6c291ac61e5ff5b682
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	GPR19 PHTF2 ADTRP ADCY2	1.75e-04	159	78	4	b05fda31b77536a1878f55d3199563b53f9420b2
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZDHHC11B RDH10 TAS1R1 ADCY2	1.75e-04	159	78	4	60b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid-cardiac_mast_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 C5AR1 ADTRP MCTP2	1.75e-04	159	78	4	766dfb9f9c0783e740a4fd395e99669310b33371
ToppCell	droplet-Lung-1m-Hematologic-myeloid-neutrophil-neutrophil\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A13 TRPM2 C5AR1 TMCC1	1.75e-04	159	78	4	be54b910ccb73e37eb81945bbad9a89d2bcec34b
ToppCell	droplet-Lung-1m-Hematologic-myeloid-neutrophil\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A13 TRPM2 C5AR1 TMCC1	1.75e-04	159	78	4	178678173b005cb8225472306657f0d8289b133b
ToppCell	facs-Lung-EPCAM-3m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A13 TRPM2 P2RY13 C5AR1	1.79e-04	160	78	4	b73f07a0088936fbc3656a05710a67f38b4ae551
ToppCell	facs-MAT-Fat-18m-Myeloid-myeloid_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 P2RY13 C5AR1 TMCC1	1.79e-04	160	78	4	bd5fa7959bfe81011b8d798535b73ea1eee008b3
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A13 TRPM2 P2RY13 C5AR1	1.79e-04	160	78	4	b88876a58fea2066468e74dcc439c8561130a910
ToppCell	droplet-Spleen-nan-24m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC31A2 C5AR1 ADTRP TMCC1	2.01e-04	165	78	4	3cdb921f5b9facf04f81995d5641ac14ef3dbb6f
ToppCell	droplet-Marrow-BM-30m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC31A2 C5AR1 ADTRP TMCC1	2.06e-04	166	78	4	019d365df44c3bbd88c1f4bdceb3de0ff76d3e8d
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNC2 C5AR1 ABCA9 SYNGR4	2.06e-04	166	78	4	bb8135119dc37fdbba476599a56d368f422688dc
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PIEZO2 ABCA12 ADTRP MCTP2	2.06e-04	166	78	4	739dfbe927f409821ff23aca6e47ebe78f57e859
ToppCell	droplet-Marrow-BM-30m-Hematologic-proerythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NT5E TRPM2 C5AR1 TMCC1	2.11e-04	167	78	4	f90cf0f29c14df4f211193326699e599ef955fa4
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 P2RY13 ADCY3 ABCA9	2.16e-04	168	78	4	4ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC31A2 C5AR1 ADTRP TMCC1	2.16e-04	168	78	4	c0ff30e2c47005514131a0866cf10a1c228128fc
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 P2RY13 ADCY3 ABCA9	2.21e-04	169	78	4	454b92b9b67299a64278c010db033ca5b9d217a0
ToppCell	droplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 P2RY13 P2RY14 MCTP2	2.21e-04	169	78	4	7962165cab84af73d20b56eb70b1ed87c94025ef
ToppCell	facs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA5 P2RY13 P2RY14 MCTP2	2.31e-04	171	78	4	6a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Mast_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA12 SLC22A10 P2RY14 EXTL3	2.31e-04	171	78	4	ac37c80c832504986c7a201d84f4b6aff5e5f323
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA12 SLC22A10 P2RY14 EXTL3	2.31e-04	171	78	4	b6502a81df4f25660f3ae4b7443a1d999df2d32b
ToppCell	facs-Marrow-T-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA5 P2RY13 P2RY14 MCTP2	2.31e-04	171	78	4	e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCell	droplet-Marrow-BM-1m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A9 NT5E C5AR1 TMCC1	2.31e-04	171	78	4	8a0c08f0aa3a80cd6346c81deb242e430ebd897b
ToppCell	356C-Lymphocytic-ILC-ILC-2\|ILC / Donor, Lineage, Cell class and subclass (all cells)	CEPT1 SLC17A9 GYS1 KIAA2013	2.36e-04	172	78	4	4977e1f4deae781750e27a8054deccd336cfb74a
ToppCell	367C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	GPR19 HID1 TBC1D8B ANO8	2.36e-04	172	78	4	fb8ab2576b5c38db63573a3bf46b8d9d634c4999
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 P2RY13 P2RY14 MCTP2	2.36e-04	172	78	4	30916a902c151907745756d14327e24adc34afef
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 KCNJ1 LGR4 ABCA9	2.41e-04	173	78	4	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FADS3 ABCA5 P2RY14 MCTP2	2.41e-04	173	78	4	4f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FADS3 ABCA5 P2RY14 MCTP2	2.41e-04	173	78	4	9bbea566964281f47bf75d665b7d69ba8326e207
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA5 MRAP HID1 ABCA9	2.47e-04	174	78	4	019eae059bd9eb107dee8f0d0f574ca36c2c26e1
ToppCell	facs-Heart-RV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR19 MRAP P2RY14 ADCY3	2.52e-04	175	78	4	bfac175b79bb7d3d81074a2407c206a7647ee75d
ToppCell	droplet-Spleen-nan-3m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 P2RY13 P2RY14 MCTP2	2.52e-04	175	78	4	21bc0e59a9509d38751ce6aad2325f341bc70eff
ToppCell	facs-Heart-RV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR19 MRAP P2RY14 ADCY3	2.52e-04	175	78	4	c94fb35bbac95123201ca87ca835aecaefc0c490
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 P2RY13 P2RY14 MCTP2	2.58e-04	176	78	4	d4075796c38b775fe721abb47426e662a0d415e3
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a7-Slc17a8.Fezf2-Slc17a8_(Layer_5,_Retrosplenial_cortex_(RSG)_and_Subiculum,_Tshz2+)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ATP8B3 ABCA12 OCA2	2.74e-04	72	78	3	e3f4d1df43cc41b0424f27485a00ddca9e905f95
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 P2RY13 P2RY14 MCTP2	2.81e-04	180	78	4	df60970520fba2ac0639faa54096766d07418ca4
ToppCell	BAL-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TXNDC15 SLC17A9 TRPV3 HID1	2.81e-04	180	78	4	6a777a308fa3160d31eda468db930e71862020b2
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Macrophages\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC31A2 P2RY13 TRPM8 C5AR1	2.87e-04	181	78	4	08bc6fe2a11d31a7e5e4a4552b04c0ebc2aefc59
ToppCell	facs-Marrow-T-cells-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNFT2 RDH10 TVP23B SLC33A1	2.87e-04	181	78	4	57f0cc749ae8b6a3d77e2af31f9a6e4739c57049
ToppCell	facs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 P2RY13 P2RY14 MCTP2	2.87e-04	181	78	4	782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCell	facs-Marrow-B-cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 P2RY13 P2RY14 MCTP2	2.87e-04	181	78	4	e2481291c236105774c53883e6f20da11941df9b
ToppCell	facs-Marrow-T-cells-3m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNFT2 RDH10 TVP23B SLC33A1	2.87e-04	181	78	4	d01b35cc2fc57991a35be6a06cb7351fbabd9a11
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY13 P2RY14 C5AR1 ADCY3	2.93e-04	182	78	4	3dec003bad0f3716cf8163861a9d4302a7d6df8c
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A13 GYS1 C5AR1 ADTRP	2.93e-04	182	78	4	9025178ede571e3808d4657ad4892152f336c9b4
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A13 GYS1 C5AR1 ADTRP	2.93e-04	182	78	4	c075756cd4bb484ede1be2bcdb9eac60eab0573a
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-5\|TCGA-Breast / Sample_Type by Project: Shred V9	ABCA12 STARD3 ABCC11 HID1	2.93e-04	182	78	4	9e48d5b634603bc7a8d29290202a311457678328
ToppCell	Globus_pallidus-Neuronal-Inhibitory\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SLC6A7 KCNC2 HCN3 ADCY2	2.93e-04	182	78	4	04ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNC2 TMEM69 P2RY14 ADCY3	2.99e-04	183	78	4	0e8fb371d8eac777451c76f41d53577f5dfb740d
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FADS3 ABCA5 LGR4 HID1	2.99e-04	183	78	4	351d575339038bd4a66f408da518c567444208e8
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNC2 TMEM69 P2RY14 ADCY3	2.99e-04	183	78	4	cbc3b00faa7e4e0dbbbc8ee105467c65241c7470
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZDHHC11B KCNJ1 LGR4 CASR	3.05e-04	184	78	4	8fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC17A9 RDH10 SLC28A3 HID1	3.05e-04	184	78	4	01c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY13 P2RY14 C5AR1 ADCY3	3.11e-04	185	78	4	afbb88325e4a81c15ac1d0a004e3e1f4ba2ee87b
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY13 P2RY14 C5AR1 ADCY3	3.11e-04	185	78	4	775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCell	LAM-Lymphoid-B-cell-2\|Lymphoid / Condition, Lineage and Cell class	TXNDC15 TRPV3 HID1 ADTRP	3.18e-04	186	78	4	bcfe0bf2f7f745146b74496a4fcfccd869ad7c6f
ToppCell	343B-Fibroblasts-Fibroblast-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	TVP23C ADCY2 ADCY3 ABCA9	3.18e-04	186	78	4	1bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell	343B-Fibroblasts-Fibroblast-E\|343B / Donor, Lineage, Cell class and subclass (all cells)	TVP23C ADCY2 ADCY3 ABCA9	3.18e-04	186	78	4	59db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNC2 NT5E P2RY14 CASR	3.24e-04	187	78	4	39756ab418267151d86f9c2553db859f71900bb1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 KCNJ1 LGR4 CASR	3.31e-04	188	78	4	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 KCNJ1 LGR4 CASR	3.31e-04	188	78	4	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	COVID-19-kidney-DCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCA5 KCNJ1 LGR4 CASR	3.31e-04	188	78	4	1d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 KCNJ1 LGR4 CASR	3.38e-04	189	78	4	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	343B-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TMEM87B TMEM254 EXTL3 ADCY3	3.38e-04	189	78	4	c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 KCNJ1 LGR4 CASR	3.38e-04	189	78	4	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 KCNJ1 LGR4 CASR	3.38e-04	189	78	4	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 KCNJ1 LGR4 CASR	3.38e-04	189	78	4	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 KCNJ1 LGR4 ABCA9	3.38e-04	189	78	4	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 KCNJ1 LGR4 CASR	3.44e-04	190	78	4	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC17A9 RDH10 SLC28A3 HID1	3.44e-04	190	78	4	23f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC17A9 RDH10 SLC28A3 HID1	3.44e-04	190	78	4	3c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 KCNJ1 LGR4 CASR	3.44e-04	190	78	4	e252e925600e6457fa6e362a55217f4cffa75cdb
Drug	8-phenyltheophylline	NT5E P2RY13 P2RY14 ADCY2 ADCY3	2.16e-06	62	77	5	CID000001922
Disease	Parkinson disease, disease progression measurement	GPR19 GPR32 SLC28A3 MCTP2	2.51e-06	39	72	4	EFO_0008336, MONDO_0005180
Disease	ARTHROGRYPOSIS, DISTAL, TYPE 2B	PIEZO2 NALCN	8.75e-05	6	72	2	C1834523
Disease	Distal arthrogryposis	PIEZO2 NALCN	2.09e-04	9	72	2	cv:C0265213

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSVQEILFPLFFLFW	ABCA5	31	Q8WWZ7
TLSDFLFFWGTVFLI	SLC33A1	256	O00400
LVFWAFLLVFSFISE	SLC7A10	431	Q9NS82
SGIWSFFFLIVVIFS	ABCA9	1136	Q8IUA7
FFAWLIESVGFLLVT	ABCA12	1111	Q86UK0
FITFSMLIFFIVWIS	CASR	806	P41180
ATASIFFGILWLFSI	GPR19	66	Q15760
RLLLVLVSAFFIFWS	GPR32	256	O75388
AFPVSTFVFLAFWIL	ADTRP	91	Q96IZ2
FLGVFVWAVFEHFLT	AADACL4	16	Q5VUY2
SVAAESFFVFWSFLI	ATP8B3	421	O60423
SFFVFWSFLILLSVT	ATP8B3	426	O60423
AIFISTFLFSLTWQF	DPY19L3	246	Q6ZPD9
FSEQFWFLLAIRLAF	ANO9	691	A1A5B4
LKVVVAVVASFFIFW	C5AR1	241	P21730
DWFSLASVIFLLLFA	DHCR7	36	Q9UBM7
VFALFNVIWSTLFLE	ANO8	286	Q9HCE9
RVEWATLLFFAALFV	OCA2	676	Q04671
LLVFTSWLVSFLIIF	OR6C1	141	Q96RD1
IFSAAFLVSWLFFGL	KCNJ4	61	P48050
VWFTFEFLVRIVFSP	KCNC2	291	Q96PR1
TIAFAVFLITVWNFE	MCTP2	691	Q6DN12
FFVVLIVFLTIFSFW	ABCC11	811	Q96J66
FLEHVFWVVSLNTLF	MARCHF6	286	O60337
FWVVSLNTLFILVFA	MARCHF6	291	O60337
IRLTVWFIFLVALFF	LGR4	541	Q9BXB1
WFIFLVALFFNLLVI	LGR4	546	Q9BXB1
WIVFNVLSDTFFLLD	HCN3	126	Q9P1Z3
VIVIFLEFFAWGLLT	MFSD14A	41	Q96MC6
FIWFFLFFISLPNTI	P2RY13	166	Q9BPV8
VSWFVFFFLLISYTV	OR4D9	206	Q8NGE8
VSPWDQVSFFLFIIF	ADCY2	131	Q08462
IVLWIALVFSFFDLI	CEPT1	371	Q9Y6K0
LDLWLFILFDVVVFL	C4orf3	46	Q8WVX3
WLSFTLFVILVFFPL	EXTL3	31	O43909
IFSDTAVLLFDFWSV	SLC31A2	6	O15432
WQVFFVFSFFITLPL	ADCY3	171	O60266
FRIFIFIFHSWILLF	CXorf1	56	O96002
AAVLWALGFIFLFTV	MT-CO1	336	P00395
FLTTWFLGEFLAQSE	GYS1	156	P13807
LLFFVAVRVLESHWF	FADS3	321	Q9Y5Q0
QALFESVIFIFVFLW	MFSD5	256	Q6N075
DFFLLIFATAVVAWA	FOCAD	1671	Q5VW36
LLVFSFFFLLTWASF	nan	881	A6NNC1
FFDLLWIVGIADFVL	RNFT2	256	Q96EX2
GSVLISFIITLLFFW	TAS2R41	136	P59536
SFVVRVSLVWIFFFL	PHTF2	556	Q8N3S3
WQVFVLAFTFLILFL	TMEM120B	301	A0PK00
FPLDFVSNLFWIFAS	TMEM191A	26	Q9H0A3
VSNLFWIFASKFIIV	TMEM191A	31	Q9H0A3
SVPFFVFFLLSRWLV	SLC22A10	266	Q63ZE4
LLHLLEAFSTTWFLF	HID1	506	Q8IV36
AFWVSLAAFVVLLFL	MRAP	41	Q8TCY5
FSWFAFLISERLSEA	TMEM69	171	Q5SWH9
TAAFWAFTVFLGDII	SHLD2	491	Q86V20
FILLSWLPTFFEETF	SLC17A9	256	Q9BYT1
LFVITVAAIFFVVWD	SLC28A3	131	Q9HAS3
FFLFLWIHVDREVLF	MRGPRX1	236	Q96LB2
QTFDFITAAWLIFLF	MRGPRX2	181	Q96LB1
FVAIFWIVFLLLIVF	P2RY14	191	Q15391
EFFVVTFKVLWAFVL	RDH10	6	Q8IZV5
SPFWSFLFFFMLLTL	SLC6A7	381	Q99884
FVTFDLLFISLLWII	STARD3	56	Q14849
GSFSLIFLSLWAVIF	NT5E	556	P21589
FFVVTLVSVFLVWKF	ALG10	326	Q5BKT4
VLWVIFAFSALFSFT	TVP23C	136	Q96ET8
LLFNFVSWIAFFTTA	TAS1R1	766	Q7RTX1
FFSSVSLSWFLTLFI	TBC1D8B	641	Q0IIM8
RLEIWFRFFFVVLTF	TMEM181	311	Q9P2C4
FSWLIFIFLQLETAK	TNFSF18	41	Q9UNG2
FFLFLLAVWVVSFGV	TRPM2	936	O94759
IVLAWALFYLFSSFT	SLC6A13	131	Q9NSD5
SVDWLLVFSLFFLIS	TXNDC15	321	Q96J42
FNILKFTWVLFLATV	PIEZO2	1646	Q9H5I5
TFSTLFLVVFIAFLW	TMCC1	621	O94876
AIAFTFFSILVWIFQ	SYNGR4	146	O95473
IILAVIDSIFVWFIF	TMEM87B	356	Q96K49
IDSIFVWFIFISLAQ	TMEM87B	361	Q96K49
VDDAFWSFLFSLILI	TMEM87B	431	Q96K49
ILSDAWFHFVFFIQA	TRPV3	516	Q8NET8
WFHFVFFIQAVLVIL	TRPV3	521	Q8NET8
VLWVIFAFSALFSFR	TVP23B	136	Q9NYZ1
DVFFFLFLFAVWMVA	TRPM8	866	Q7Z2W7
WAVFVGLSLATFRIF	ZDHHC11B	46	P0C7U3
LWFLQTFFFGIASLT	TMEM254	96	Q8TBM7
WVVVIILINFFSFFL	XK	236	P51811
PFLFWFSVASLITLF	KIAA2013	591	Q8IYS2
RFIFFVDIWTTVLDL	KCNJ1	61	P48048
EQIWSVSIFLLFFLL	NALCN	176	Q8IZF0