Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	MAP kinase kinase kinase activity	RAF1 RIPK1 MAP3K8 MAP3K4 MAP3K15	8.40e-07	27	132	5	GO:0004709
GeneOntologyMolecularFunction	protein serine kinase activity	RAF1 RIPK3 RIPK1 MARK1 MARK3 MAP3K8 OBSCN MAP3K4 NRK MAP3K15 MARK2 DYRK2	5.36e-06	363	132	12	GO:0106310
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	RAF1 RIPK3 RIPK1 MARK1 MARK3 MAP3K8 OBSCN MAP3K4 NRK MAP3K15 MARK2 DYRK2	4.13e-05	446	132	12	GO:0004674
GeneOntologyMolecularFunction	steroid 11-beta-monooxygenase activity	CYP11B1 CYP11B2	4.34e-05	2	132	2	GO:0004507
GeneOntologyMolecularFunction	corticosterone 18-monooxygenase activity	CYP11B1 CYP11B2	4.34e-05	2	132	2	GO:0047783
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	RAF1 RIPK3 RIPK1 MARK1 MARK3 POLA1 MAP3K8 OBSCN MAP3K4 FCSK FKTN NRK MAP3K15 MARK2 POLQ DYRK2 DNTT	1.52e-04	938	132	17	GO:0016772
GeneOntologyMolecularFunction	tau-protein kinase activity	MARK1 MARK3 MARK2	3.97e-04	22	132	3	GO:0050321
GeneOntologyMolecularFunction	DNA-directed DNA polymerase activity	POLA1 POLQ DNTT	5.84e-04	25	132	3	GO:0003887
GeneOntologyMolecularFunction	protein kinase activity	RAF1 RIPK3 RIPK1 MARK1 MARK3 MAP3K8 OBSCN MAP3K4 NRK MAP3K15 MARK2 DYRK2	6.39e-04	600	132	12	GO:0004672
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	RAF1 RIPK3 RIPK1 MARK1 MARK3 MAP3K8 OBSCN MAP3K4 FCSK NRK MAP3K15 MARK2 DYRK2	8.52e-04	709	132	13	GO:0016773
MousePheno	increased myocardial fiber size	RAF1 XIRP1 CYP11B1 CYP11B2 XIRP2	4.27e-05	53	103	5	MP:0004564
MousePheno	abnormal urine progesterone level	CYP11B1 CYP11B2	5.38e-05	2	103	2	MP:0011545
MousePheno	abnormal urine deoxycorticosterone level	CYP11B1 CYP11B2	5.38e-05	2	103	2	MP:0011552
MousePheno	decreased urine corticosterone level	CYP11B1 CYP11B2	5.38e-05	2	103	2	MP:0011550
MousePheno	increased urine deoxycorticosterone level	CYP11B1 CYP11B2	5.38e-05	2	103	2	MP:0011553
MousePheno	increased urine progesterone level	CYP11B1 CYP11B2	5.38e-05	2	103	2	MP:0011546
MousePheno	increased circulating adrenocorticotropin level	CYP11B1 CYP11B2 CNR1	1.33e-04	14	103	3	MP:0001748
Domain	MARK/par1	MARK1 MARK3 MARK2	1.40e-06	4	133	3	IPR033624
Domain	KA1	MARK1 MARK3 MARK2	3.49e-06	5	133	3	PF02149
Domain	KA1_dom	MARK1 MARK3 MARK2	3.49e-06	5	133	3	IPR001772
Domain	KA1	MARK1 MARK3 MARK2	3.49e-06	5	133	3	PS50032
Domain	-	MARK1 MARK3 MARK2	3.49e-06	5	133	3	3.30.310.80
Domain	WD40_repeat_dom	KNTC1 DPH7 UBR4 APAF1 SPAG9 EIPR1 NUP37 STRN4 HERC1 DYNC1I2 FBXW7	9.24e-06	297	133	11	IPR017986
Domain	Ser/Thr_kinase_AS	RAF1 RIPK3 RIPK1 MARK1 MARK3 MAP3K8 OBSCN MAP3K4 NRK MAP3K15 MARK2 DYRK2	9.54e-06	357	133	12	IPR008271
Domain	S_TKc	RAF1 RIPK3 RIPK1 MARK1 MARK3 MAP3K8 OBSCN MAP3K4 NRK MAP3K15 MARK2 DYRK2	1.01e-05	359	133	12	SM00220
Domain	PROTEIN_KINASE_ST	RAF1 RIPK3 RIPK1 MARK1 MARK3 MAP3K8 OBSCN MAP3K4 NRK MAP3K15 MARK2 DYRK2	1.10e-05	362	133	12	PS00108
Domain	KA1/Ssp2_C	MARK1 MARK3 MARK2	1.21e-05	7	133	3	IPR028375
Domain	Pkinase	RAF1 RIPK3 RIPK1 MARK1 MARK3 MAP3K8 OBSCN MAP3K4 NRK MAP3K15 MARK2 DYRK2	1.83e-05	381	133	12	PF00069
Domain	Actin-binding_Xin_repeat	XIRP1 XIRP2	5.03e-05	2	133	2	IPR012510
Domain	Cyt_P450_mitochondrial	CYP11B1 CYP11B2	5.03e-05	2	133	2	IPR002399
Domain	XIRP1/XIRP2	XIRP1 XIRP2	5.03e-05	2	133	2	IPR030072
Domain	XIN	XIRP1 XIRP2	5.03e-05	2	133	2	PS51389
Domain	Xin	XIRP1 XIRP2	5.03e-05	2	133	2	PF08043
Domain	Kinase-like_dom	RAF1 RIPK3 RIPK1 MARK1 MARK3 MAP3K8 OBSCN MAP3K4 NRK MACF1 MAP3K15 MARK2 DYRK2	1.34e-04	542	133	13	IPR011009
Domain	-	DPH7 APAF1 SPAG9 EIPR1 NUP37 STRN4 HERC1 DYNC1I2 SEMA3E FBXW7	1.38e-04	333	133	10	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	DPH7 APAF1 SPAG9 EIPR1 NUP37 STRN4 HERC1 DYNC1I2 SEMA3E FBXW7	1.45e-04	335	133	10	IPR015943
Domain	RHIM	RIPK3 RIPK1	1.50e-04	3	133	2	PF12721
Domain	RHIM_dom	RIPK3 RIPK1	1.50e-04	3	133	2	IPR025735
Domain	WD40_repeat_CS	DPH7 APAF1 EIPR1 NUP37 STRN4 HERC1 FBXW7	1.74e-04	164	133	7	IPR019775
Domain	Prot_kinase_dom	RAF1 RIPK3 RIPK1 MARK1 MARK3 MAP3K8 OBSCN MAP3K4 NRK MAP3K15 MARK2 DYRK2	1.98e-04	489	133	12	IPR000719
Domain	PROTEIN_KINASE_DOM	RAF1 RIPK3 RIPK1 MARK1 MARK3 MAP3K8 OBSCN MAP3K4 NRK MAP3K15 MARK2 DYRK2	2.13e-04	493	133	12	PS50011
Domain	Protein_kinase_ATP_BS	RAF1 RIPK3 MARK1 MARK3 OBSCN MAP3K4 NRK MAP3K15 MARK2 DYRK2	3.88e-04	379	133	10	IPR017441
Domain	PROTEIN_KINASE_ATP	RAF1 RIPK3 MARK1 MARK3 MAP3K8 OBSCN MAP3K4 NRK MAP3K15 MARK2 DYRK2	4.49e-04	459	133	11	PS00107
Domain	WD40	DPH7 APAF1 EIPR1 NUP37 STRN4 HERC1 DYNC1I2 FBXW7	5.41e-04	259	133	8	PF00400
Domain	WD40	DPH7 APAF1 EIPR1 NUP37 STRN4 HERC1 DYNC1I2 FBXW7	6.77e-04	268	133	8	SM00320
Domain	WD40_repeat	DPH7 APAF1 EIPR1 NUP37 STRN4 HERC1 DYNC1I2 FBXW7	7.46e-04	272	133	8	IPR001680
Domain	WD_REPEATS_1	DPH7 APAF1 EIPR1 NUP37 STRN4 HERC1 DYNC1I2 FBXW7	8.59e-04	278	133	8	PS00678
Domain	WD_REPEATS_2	DPH7 APAF1 EIPR1 NUP37 STRN4 HERC1 DYNC1I2 FBXW7	8.79e-04	279	133	8	PS50082
Domain	WD_REPEATS_REGION	DPH7 APAF1 EIPR1 NUP37 STRN4 HERC1 DYNC1I2 FBXW7	8.79e-04	279	133	8	PS50294
Domain	GAF	PDE6A PDE11A	1.03e-03	7	133	2	PF01590
Domain	UBA	MARK1 MARK3 MARK2	1.25e-03	30	133	3	SM00165
Domain	GAF	PDE6A PDE11A	1.37e-03	8	133	2	IPR003018
Domain	GAF	PDE6A PDE11A	1.37e-03	8	133	2	SM00065
Domain	-	PDE6A PDE11A	1.75e-03	9	133	2	3.30.450.40
Domain	GAF_dom-like	PDE6A PDE11A	1.75e-03	9	133	2	IPR029016
Domain	UBA	MARK1 MARK3 MARK2	2.12e-03	36	133	3	PF00627
Domain	ARM-type_fold	USP34 UBR4 CKAP5 ARFGEF2 TSC2 THADA RNPEP XPO6	2.98e-03	339	133	8	IPR016024
Domain	UBA	MARK1 MARK3 MARK2	3.78e-03	44	133	3	IPR015940
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH7	4.33e-03	14	133	2	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DNAH7	4.33e-03	14	133	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH7	4.33e-03	14	133	2	IPR013602
Domain	DHC_N2	DNAH3 DNAH7	4.33e-03	14	133	2	PF08393
Domain	MT	DNAH3 DNAH7	4.33e-03	14	133	2	PF12777
Domain	AAA_8	DNAH3 DNAH7	4.33e-03	14	133	2	PF12780
Domain	UBA	MARK1 MARK3 MARK2	4.55e-03	47	133	3	PS50030
Domain	DHC_fam	DNAH3 DNAH7	4.97e-03	15	133	2	IPR026983
Domain	Dynein_heavy	DNAH3 DNAH7	4.97e-03	15	133	2	PF03028
Domain	Dynein_heavy_dom	DNAH3 DNAH7	4.97e-03	15	133	2	IPR004273
Pubmed	Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions.	MARK1 MARK3 CKAP5 MARK2	1.50e-08	8	135	4	22298430
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	RAF1 KNTC1 ERCC6L MARK3 UBR4 HNRNPA3 TSC2 SPAG9 PRPF6 EIPR1 LOXHD1 GANAB CLEC2L TIMP2 XPO6 STRN4 MARK2 HERC1 POLQ DYNC1I2	1.28e-07	1284	135	20	17353931
Pubmed	Role of individual MARK isoforms in phosphorylation of tau at Ser²⁶² in Alzheimer's disease.	MARK1 MARK3 MARK2	1.13e-06	6	135	3	23666762
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	RAF1 PDE6A UBR4 OBSCN CKAP5 TNS2 SPAG9 PRPF6 FCSK	3.16e-06	304	135	9	32235678
Pubmed	14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK.	RAF1 MARK1 MARK3 MARK2	5.50e-06	30	135	4	16306228
Pubmed	LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.	RIPK3 RIPK1 RBCK1	9.22e-06	11	135	3	29695863
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP34 POLA1 UBR4 HNRNPA3 CKAP5 YTHDC2 SPAG9 PRPF6 GANAB RNPEP DLAT MACF1	9.84e-06	653	135	12	22586326
Pubmed	LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L.	RIPK3 RIPK1 RBCK1	1.23e-05	12	135	3	30254289
Pubmed	RIP1K and RIP3K provoked by shikonin induce cell cycle arrest in the triple negative breast cancer cell line, MDA-MB-468: necroptosis as a desperate programmed suicide pathway.	RIPK3 RIPK1	1.50e-05	2	135	2	26496737
Pubmed	The Bcr-Abl inhibitor GNF-7 inhibits necroptosis and ameliorates acute kidney injury by targeting RIPK1 and RIPK3 kinases.	RIPK3 RIPK1	1.50e-05	2	135	2	32247850
Pubmed	Common polymorphisms in the CYP11B1 and CYP11B2 genes: evidence for a digenic influence on hypertension.	CYP11B1 CYP11B2	1.50e-05	2	135	2	23150505
Pubmed	GRAde: a long-read sequencing approach to efficiently identifying the CYP11B1/CYP11B2 chimeric form in patients with glucocorticoid-remediable aldosteronism.	CYP11B1 CYP11B2	1.50e-05	2	135	2	35012455
Pubmed	Role of genetic variation in regulation of aldosterone biosynthesis.	CYP11B1 CYP11B2	1.50e-05	2	135	2	21164264
Pubmed	RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome.	RIPK3 RIPK1	1.50e-05	2	135	2	28176780
Pubmed	Concerted action of CB1 cannabinoid receptor and deleted in colorectal cancer in axon guidance.	DCC CNR1	1.50e-05	2	135	2	21273433
Pubmed	Positive and negative phosphorylation regulates RIP1- and RIP3-induced programmed necrosis.	RIPK3 RIPK1	1.50e-05	2	135	2	24059293
Pubmed	The Role of RIPK1/3 in Adult Onset Still's Disease Patients With Liver Damage: A Preliminary Study.	RIPK3 RIPK1	1.50e-05	2	135	2	33329521
Pubmed	The hamster adrenal cytochrome P450C11 has equipotent 11beta-hydroxylase and 19-hydroxylase activities, but no aldosterone synthase activity.	CYP11B1 CYP11B2	1.50e-05	2	135	2	8645611
Pubmed	Emergence of Xin demarcates a key innovation in heart evolution.	XIRP1 XIRP2	1.50e-05	2	135	2	18682726
Pubmed	Expression and localization of cytochrome P450(11beta,aldo) mRNA in the frog brain.	CYP11B1 CYP11B2	1.50e-05	2	135	2	12231255
Pubmed	A de novo unequal cross-over mutation between CYP11B1 and CYP11B2 genes causes familial hyperaldosteronism type I.	CYP11B1 CYP11B2	1.50e-05	2	135	2	20634641
Pubmed	Hereditary hypertension caused by chimaeric gene duplications and ectopic expression of aldosterone synthase.	CYP11B1 CYP11B2	1.50e-05	2	135	2	1303253
Pubmed	Mosaic composition of RIP1-RIP3 signalling hub and its role in regulating cell death.	RIPK3 RIPK1	1.50e-05	2	135	2	35256774
Pubmed	Distinctive roles of receptor-interacting protein kinases 1 and 3 in caspase-independent cell death of L929.	RIPK3 RIPK1	1.50e-05	2	135	2	23584955
Pubmed	Necroptosis in cardiovascular disease - a new therapeutic target.	RIPK3 RIPK1	1.50e-05	2	135	2	29524460
Pubmed	The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis.	RIPK3 RIPK1	1.50e-05	2	135	2	24314238
Pubmed	Role of steroid 11 beta-hydroxylase and steroid 18-hydroxylase in the biosynthesis of glucocorticoids and mineralocorticoids in humans.	CYP11B1 CYP11B2	1.50e-05	2	135	2	1741400
Pubmed	The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclophosphamide and busulphan in mice.	RIPK3 RIPK1	1.50e-05	2	135	2	25674205
Pubmed	RIP1 kinase mediates angiogenesis by modulating macrophages in experimental neovascularization.	RIPK3 RIPK1	1.50e-05	2	135	2	31685620
Pubmed	Effects of intron conversion in the human CYP11B2 gene on its transcription and blood pressure regulation in transgenic mice.	CYP11B1 CYP11B2	1.50e-05	2	135	2	32540969
Pubmed	Investigation on the expression regulation of RIPK1/RIPK3 in the retinal ganglion cells (RGCs) cultured in high glucose.	RIPK3 RIPK1	1.50e-05	2	135	2	34281454
Pubmed	Inhibition of aldosterone synthase (CYP11B2) by torasemide prevents atrial fibrosis and atrial fibrillation in mice.	CYP11B1 CYP11B2	1.50e-05	2	135	2	26047574
Pubmed	Aldosterone synthase knockout mouse as a model for sodium-induced endothelial sodium channel up-regulation in vascular endothelium.	CYP11B1 CYP11B2	1.50e-05	2	135	2	26324851
Pubmed	Microsatellite polymorphism analysis allows the individual assignment of the rat 11 beta-hydroxylase gene (Cyp11b1) and the rat aldosterone synthase gene (Cyp11b2) to chromosome 7 using rat x mouse somatic cell hybrids and identifies differences between and within various rat strains.	CYP11B1 CYP11B2	1.50e-05	2	135	2	7669222
Pubmed	Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron.	CYP11B1 CYP11B2	1.50e-05	2	135	2	22933298
Pubmed	Structural and functional analysis of the promoter region of the gene encoding mouse steroid 11 beta-hydroxylase.	CYP11B1 CYP11B2	1.50e-05	2	135	2	2783417
Pubmed	Cloning and expression of a cDNA for human cytochrome P-450aldo as related to primary aldosteronism.	CYP11B1 CYP11B2	1.50e-05	2	135	2	2256920
Pubmed	K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo.	RIPK3 RIPK1	1.50e-05	2	135	2	27258786
Pubmed	The diverse role of RIP kinases in necroptosis and inflammation.	RIPK3 RIPK1	1.50e-05	2	135	2	26086143
Pubmed	Association of DNA polymorphisms within the CYP11B2/CYP11B1 locus and postoperative hypertension risk in the patients with aldosterone-producing adenomas.	CYP11B1 CYP11B2	1.50e-05	2	135	2	20708777
Pubmed	Molecular genetic studies on the biosynthesis of aldosterone in humans.	CYP11B1 CYP11B2	1.50e-05	2	135	2	22217843
Pubmed	Mechanistic study of polychlorinated biphenyl 126-induced CYP11B1 and CYP11B2 up-regulation.	CYP11B1 CYP11B2	1.50e-05	2	135	2	16396990
Pubmed	Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo.	RIPK3 RIPK1	1.50e-05	2	135	2	25015821
Pubmed	FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2.	DYRK2 FBXW7	1.50e-05	2	135	2	36934104
Pubmed	Structural variations in the catalytic and ubiquitin-associated domains of microtubule-associated protein/microtubule affinity regulating kinase (MARK) 1 and MARK2.	MARK1 MARK2	1.50e-05	2	135	2	16803889
Pubmed	Programmed necrosis and necroptosis signalling.	RIPK3 RIPK1	1.50e-05	2	135	2	25327580
Pubmed	RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury.	RIPK3 RIPK1	1.50e-05	2	135	2	34404478
Pubmed	[123 I]Iodometomidate for molecular imaging of adrenocortical cytochrome P450 family 11B enzymes.	CYP11B1 CYP11B2	1.50e-05	2	135	2	18397978
Pubmed	Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2.	CYP11B1 CYP11B2	1.50e-05	2	135	2	1518866
Pubmed	Sensitizing acute myeloid leukemia cells to induced differentiation by inhibiting the RIP1/RIP3 pathway.	RIPK3 RIPK1	1.50e-05	2	135	2	27748372
Pubmed	Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury.	RIPK3 RIPK1	1.50e-05	2	135	2	25950489
Pubmed	Procollagen I-expressing renin cell precursors.	CYP11B1 CYP11B2	1.50e-05	2	135	2	23761669
Pubmed	Characterization of two genes encoding human steroid 11 beta-hydroxylase (P-450(11) beta).	CYP11B1 CYP11B2	1.50e-05	2	135	2	2592361
Pubmed	Lactobacillus rhamnosus 76 alleviates airway inflammation in ovalbumin-allergic mice and improves mucus secretion by down-regulating STAT6/SPDEF pathway.	STAT6 SPDEF	1.50e-05	2	135	2	37515878
Pubmed	Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice.	CYP11B1 CYP11B2	1.50e-05	2	135	2	23314847
Pubmed	Effect of variation in CYP11B1 and CYP11B2 on corticosteroid phenotype and hypothalamic-pituitary-adrenal axis activity in hypertensive and normotensive subjects.	CYP11B1 CYP11B2	1.50e-05	2	135	2	17980006
Pubmed	Association between aldosterone production and variation in the 11beta-hydroxylase (CYP11B1) gene.	CYP11B1 CYP11B2	1.50e-05	2	135	2	16984984
Pubmed	Evidence for local aldosterone synthesis in the large intestine of the mouse.	CYP11B1 CYP11B2	1.50e-05	2	135	2	35288482
Pubmed	Homeostatic responses in the adrenal cortex to the absence of aldosterone in mice.	CYP11B1 CYP11B2	1.50e-05	2	135	2	15731365
Pubmed	Targeting RIP Kinases in Chronic Inflammatory Disease.	RIPK3 RIPK1	1.50e-05	2	135	2	33924766
Pubmed	Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis.	RIPK3 RIPK1	1.50e-05	2	135	2	21098270
Pubmed	Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis.	MARK3 MARK2	1.50e-05	2	135	2	20733003
Pubmed	The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation.	RAF1 HERC1	1.50e-05	2	135	2	30140388
Pubmed	Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study.	CYP11B1 CYP11B2	1.50e-05	2	135	2	17651452
Pubmed	Receptor-interacting protein 1 and 3 kinase activity are required for high-fat diet induced liver injury in mice.	RIPK3 RIPK1	1.50e-05	2	135	2	38161978
Pubmed	Expression of CYP11B1 and CYP11B2 in adrenal adenoma correlates with clinical characteristics of primary aldosteronism.	CYP11B1 CYP11B2	1.50e-05	2	135	2	34743356
Pubmed	Evaluation of RIP1K and RIP3K expressions in the malignant and benign breast tumors.	RIPK3 RIPK1	1.50e-05	2	135	2	26749282
Pubmed	Polymorphisms in CYP11B2 and CYP11B1 genes associated with primary hyperaldosteronism.	CYP11B1 CYP11B2	1.50e-05	2	135	2	20339375
Pubmed	RIP3 S-nitrosylation contributes to cerebral ischemic neuronal injury.	RIPK3 RIPK1	1.50e-05	2	135	2	26319693
Pubmed	Lysosomal damage after spinal cord injury causes accumulation of RIPK1 and RIPK3 proteins and potentiation of necroptosis.	RIPK3 RIPK1	1.50e-05	2	135	2	29686269
Pubmed	Genetic analyses of the chimeric CYP11B1/CYP11B2 gene in a Korean family with glucocorticoid-remediable aldosteronism.	CYP11B1 CYP11B2	1.50e-05	2	135	2	20808686
Pubmed	RIPK1 and RIPK3 regulate TNFα-induced β-cell death in concert with caspase activity.	RIPK3 RIPK1	1.50e-05	2	135	2	36030035
Pubmed	Molecular Pathways: The Necrosome-A Target for Cancer Therapy.	RIPK3 RIPK1	1.50e-05	2	135	2	27932417
Pubmed	Expression of Protein Kinases RIPK-1 and RIPK-3 in Mouse and Human Hair Follicle.	RIPK3 RIPK1	1.50e-05	2	135	2	33119828
Pubmed	Aldosterone decreases glucose-stimulated insulin secretion in vivo in mice and in murine islets.	CYP11B1 CYP11B2	1.50e-05	2	135	2	21519965
Pubmed	Cell Death and Inflammation - A Vital but Dangerous Liaison.	RIPK3 RIPK1	1.50e-05	2	135	2	31003931
Pubmed	Diagnosis of glucocorticoid-remediable aldosteronism in hypertensive children.	CYP11B1 CYP11B2	1.50e-05	2	135	2	21625068
Pubmed	Genetic screening for glucocorticoid-remediable aldosteronism (GRA): experience of three clinical centres in Poland.	CYP11B1 CYP11B2	1.50e-05	2	135	2	16110193
Pubmed	Chimeric CYP11B2/CYP11B1 causing 11β-hydroxylase deficiency in Chinese patients with congenital adrenal hyperplasia.	CYP11B1 CYP11B2	1.50e-05	2	135	2	26066897
Pubmed	Astrocyte-Derived TNF-α-Activated Platelets Promote Cerebral Ischemia/Reperfusion Injury by Regulating the RIP1/RIP3/AKT Signaling Pathway.	RIPK3 RIPK1	1.50e-05	2	135	2	35781632
Pubmed	RIPK3 and RIPK1 gene expression in pterygium: unveiling molecular insights into pathogenesis.	RIPK3 RIPK1	1.50e-05	2	135	2	38630344
Pubmed	Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3.	RIPK3 RIPK1	1.50e-05	2	135	2	11734559
Pubmed	Cytotoxicity and decreased corticosterone production in adrenocortical Y-1 cells by 3-methylsulfonyl-DDE and structurally related molecules.	CYP11B1 CYP11B2	1.50e-05	2	135	2	18651133
Pubmed	A new presentation of the chimeric CYP11B1/CYP11B2 gene with low prevalence of primary aldosteronism and atypical gene segregation pattern.	CYP11B1 CYP11B2	1.50e-05	2	135	2	22083159
Pubmed	Role of receptor-interacting protein 1/receptor-interacting protein 3 in inflammation and necrosis following chronic constriction injury of the sciatic nerve.	RIPK3 RIPK1	1.50e-05	2	135	2	30192300
Pubmed	Editorial: polymorphisms in CYP11B genes and 11-hydroxylase activity.	CYP11B1 CYP11B2	1.50e-05	2	135	2	15699546
Pubmed	Cyp11b1 is induced in the murine gonad by luteinizing hormone/human chorionic gonadotropin and involved in the production of 11-ketotestosterone, a major fish androgen: conservation and evolution of the androgen metabolic pathway.	CYP11B1 CYP11B2	1.50e-05	2	135	2	18162527
Pubmed	Chronic activation of adrenal Gq signaling induces Cyp11b2 expression in the zona fasciculata and hyperaldosteronism.	CYP11B1 CYP11B2	1.50e-05	2	135	2	38341019
Pubmed	Adrenal CYP11B1/2 expression in primary aldosteronism: immunohistochemical analysis using novel monoclonal antibodies.	CYP11B1 CYP11B2	1.50e-05	2	135	2	24837548
Pubmed	Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity.	CYP11B1 CYP11B2	1.50e-05	2	135	2	30046010
Pubmed	Familial and phenotypic associations of the aldosterone Renin ratio.	CYP11B1 CYP11B2	1.50e-05	2	135	2	19820005
Pubmed	The Mast Cell-SCF-CB1 Interaction Is a Key Player in Seborrheic Keratosis.	KITLG CNR1	1.50e-05	2	135	2	32578480
Pubmed	RIP3, a novel apoptosis-inducing kinase.	RIPK3 RIPK1	1.50e-05	2	135	2	10358032
Pubmed	Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.	CYP11B1 CYP11B2	1.50e-05	2	135	2	22622494
Pubmed	Receptor-interacting protein kinases modulate noise-induced sensory hair cell death.	RIPK3 RIPK1	1.50e-05	2	135	2	24874734
Pubmed	Mutation analysis of CYP11B1 and CYP11B2 in patients with increased 18-hydroxycortisol production.	CYP11B1 CYP11B2	1.50e-05	2	135	2	15062555
Pubmed	Disturbed homeostasis in sodium-restricted mice heterozygous and homozygous for aldosterone synthase gene disruption.	CYP11B1 CYP11B2	1.50e-05	2	135	2	17075030
Pubmed	Polymorphic variation in the 11beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency.	CYP11B1 CYP11B2	1.50e-05	2	135	2	17075029
Pubmed	Herpes simplex virus suppresses necroptosis in human cells.	RIPK3 RIPK1	1.50e-05	2	135	2	25674983
Pubmed	RIP1/RIP3 binding to HSV-1 ICP6 initiates necroptosis to restrict virus propagation in mice.	RIPK3 RIPK1	1.50e-05	2	135	2	25674982
Interaction	C3orf18 interactions	KNTC1 CKAP5 ARFGEF2 TSC2 SPAG9 THADA COG1 XPO6	1.01e-06	115	134	8	int:C3orf18
Interaction	NPTN interactions	KNTC1 VPS50 ARFGEF2 TSC2 FCSK THADA GANAB COG1 XPO6 ZFYVE26 TFB2M	2.59e-06	278	134	11	int:NPTN
Interaction	DHRS12 interactions	MARK1 MARK3 CALHM4 MARK2	1.02e-05	21	134	4	int:DHRS12
Interaction	SIGLECL1 interactions	KNTC1 ARFGEF2 TSC2 DEPDC1 MAP3K4 THADA XPO6	1.06e-05	113	134	7	int:SIGLECL1
Interaction	USP21 interactions	RIPK1 MARK1 MARK3 CKAP5 RTKN RBCK1 FUCA1 MARK2	1.24e-05	161	134	8	int:USP21
Interaction	BCKDK interactions	RAF1 TNS2 MAP3K4 DLAT SMPD2 TAFAZZIN DYNC1I2 FBXW7	1.55e-05	166	134	8	int:BCKDK
Interaction	FUCA1 interactions	MARK1 MARK3 FUCA1 MARK2	2.91e-05	27	134	4	int:FUCA1
Interaction	EEF1AKMT3 interactions	RAF1 KNTC1 USP34 RIPK1 ERCC6L APAF1 TSC2 RTKN RBCK1 STRN4 HERC1	3.25e-05	364	134	11	int:EEF1AKMT3
Interaction	CLASP1 interactions	RAF1 MARK3 CKAP5 MACF1 MARK2 DYNC1I2 FBXW7	3.86e-05	138	134	7	int:CLASP1
Interaction	CDH19 interactions	MARK1 MARK3 MARK2 FBXW7	4.48e-05	30	134	4	int:CDH19
Interaction	ZNF550 interactions	USP34 YTHDC2 STRN4 PSAPL1 ZNF714	7.23e-05	65	134	5	int:ZNF550
Interaction	OPALIN interactions	RAF1 KNTC1 VPS50 ARFGEF2 TSC2 THADA XPO6 TFB2M	7.98e-05	209	134	8	int:OPALIN
Interaction	TFDP3 interactions	ERCC6L POLA1 UBR4 HERC1	9.33e-05	36	134	4	int:TFDP3
Cytoband	11q13.1	NUDT22 ACTN3 MARK2 SLC22A20P	3.72e-05	63	135	4	11q13.1
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	RAF1 MAP3K8 MAP3K4 MAP3K15	4.94e-06	24	87	4	654
GeneFamily	WD repeat domain containing	DPH7 APAF1 EIPR1 NUP37 STRN4 HERC1 DYNC1I2 FBXW7	3.80e-05	262	87	8	362
GeneFamily	Cytochrome P450 family 11	CYP11B1 CYP11B2	6.85e-05	3	87	2	1007
GeneFamily	DNA polymerases	POLA1 POLQ DNTT	1.78e-04	23	87	3	535
GeneFamily	Speedy/RINGO cell cycle regulator family	SPDYE7P SPDYE3	1.46e-03	12	87	2	756
GeneFamily	Dyneins, axonemal	DNAH3 DNAH7	2.97e-03	17	87	2	536
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ADCY10 APAF1 OBSCN DCC GPR88 HS6ST3	1.24e-07	77	134	6	a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
ToppCell	PBMC-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	KNTC1 DPY19L2 ERCC6L POLA1 DEPDC1 CLCN4 POLQ	1.73e-06	189	134	7	946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ADCY10 APAF1 OBSCN GPR88 HS6ST3	2.25e-06	70	134	5	8d6bdf2e773e894a0db39fdff1fafc2474e03fcf
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-Neurons\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	AAGAB PTX3 SPDYE3 DLAT TMEM108 HS6ST3 CNR1	2.35e-06	198	134	7	90ebefc9ba8dc2a81471e5693384f5ce56f06298
ToppCell	facs-Marrow-B-cells-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC43A1 OOSP2 TG CLEC2L KEL ACMSD	1.08e-05	165	134	6	361a605d8f833d9ec54b120480dce397da35f9c3
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 ERCC6L CKAP5 DEPDC1 SLFN13 POLQ	1.46e-05	174	134	6	dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
Disease	visual impairment and progressive phthisis bulbi (implicated_via_orthology)	MARK1 MARK3 MARK2	3.49e-07	4	132	3	DOID:0070356 (implicated_via_orthology)
Disease	Glucocorticoid-remediable aldosteronism	CYP11B1 CYP11B2	1.99e-05	2	132	2	C1260386
Disease	adrenal cortical adenoma (is_marker_for)	CYP11B1 CYP11B2	1.99e-05	2	132	2	DOID:0050891 (is_marker_for)
Disease	congenital adrenal hyperplasia (implicated_via_orthology)	CYP11B1 CYP11B2	5.94e-05	3	132	2	DOID:0050811 (implicated_via_orthology)
Disease	Adenocarcinoma of large intestine	RIPK1 DCC NRK MAP3K15 FBXW7	7.32e-05	96	132	5	C1319315
Disease	Ovarian Serous Adenocarcinoma	RAF1 MARK1 MAP3K4	1.45e-04	23	132	3	C1335177
Disease	primary hyperaldosteronism (is_implicated_in)	CYP11B1 CYP11B2	1.97e-04	5	132	2	DOID:446 (is_implicated_in)
Disease	Conn Syndrome	CYP11B1 CYP11B2	2.94e-04	6	132	2	C1384514
Disease	glucagon measurement, glucose tolerance test	MACF1 HERC1	2.94e-04	6	132	2	EFO_0004307, EFO_0008463
Disease	Hyperaldosteronism	CYP11B1 CYP11B2	2.94e-04	6	132	2	C0020428
Disease	protocadherin alpha-7 measurement	CYP11B1 CYP11B2	4.11e-04	7	132	2	EFO_0801973
Disease	myocarditis (biomarker_via_orthology)	CYP11B1 STAT6	4.11e-04	7	132	2	DOID:820 (biomarker_via_orthology)
Disease	Seizures	TSC2 FCSK FKTN MACF1 FUCA1 CNR1	4.59e-04	218	132	6	C0036572
Disease	protein FAM163B measurement	CYP11B1 CYP11B2	7.00e-04	9	132	2	EFO_0802936
Disease	androstenedione measurement	CYP11B1 CYP11B2	8.73e-04	10	132	2	EFO_0007972
Disease	WNT1-inducible-signaling pathway protein 1 measurement	TG C8B	8.73e-04	10	132	2	EFO_0008321
Disease	Intellectual Disability	DCC FCSK PTCHD1 MACF1 FUCA1 TFB2M MED23 DYNC1I2	9.35e-04	447	132	8	C3714756
Disease	Familial dilated cardiomyopathy	RAF1 FKTN TAFAZZIN	1.01e-03	44	132	3	C0340427
Disease	cell growth regulator with EF hand domain protein 1 measurement	CYP11B1 CYP11B2	1.06e-03	11	132	2	EFO_0801461
Disease	3-hydroxyanthranilate 3,4-dioxygenase measurement	CYP11B1 CYP11B2	1.06e-03	11	132	2	EFO_0021862
Disease	Mental Retardation, X-Linked Nonsyndromic	PTCHD1 CLCN4	1.50e-03	13	132	2	C3501611
Disease	IGFBP-3 measurement	TSC2 FCSK GREB1	1.84e-03	54	132	3	EFO_0004626
Disease	chenodeoxycholate measurement	DCC SLC22A20P	2.01e-03	15	132	2	EFO_0010471
Disease	hypertension (implicated_via_orthology)	CYP11B1 CYP11B2 RNPEP CNR1	2.66e-03	128	132	4	DOID:10763 (implicated_via_orthology)
Disease	mosquito bite reaction itch intensity measurement	RAF1 MAP3K8 STAT6 TMEM108	2.74e-03	129	132	4	EFO_0008377
Disease	urinary microalbumin measurement	RASSF10 YTHDC2	3.58e-03	20	132	2	EFO_0010967
Disease	neurodegenerative disease (implicated_via_orthology)	MARK1 MARK3 HNRNPA3 MARK2	4.16e-03	145	132	4	DOID:1289 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
DVCVMETWNPEKAAS	SYT13	141	Q7L8C5
TCKQWLQMEESLEVP	C2orf16	406	Q68DN1
PTKVLCILWDMETEE	APAF1	396	O14727
ELDMKAIEAVAISPW	RNPEP	516	Q9H4A4
VRWLCAVSMDELASP	ARFGEF2	1091	Q9Y6D5
QKPCFTTDMVTWALL	ARHGEF4	26	Q9NR80
VKMASECNWSDPLVE	CFAP46	921	Q8IYW2
WLVGMPAETTIAICS	ACMSD	191	Q8TDX5
TLDSWEPELVKLMCE	ACAP1	461	Q15027
PLMAAAVTSKWVADA	CLCN4	551	P51793
TTELLFEILPCWNMK	ADCY10	841	Q96PN6
RVALSSCVPDWKELM	FAM200A	551	Q8TCP9
SVDMLLPSKCPSWEE	DLGAP4	421	Q9Y2H0
WMKTVPTENCDVLMT	ANO8	56	Q9HCE9
CSTKVPTMCVDWSNI	RAF1	176	P04049
MDPSEKKISVWICQE	RASSF10	1	A6NK89
CSLDWLMVSVIPVAE	OOSP2	26	Q86WS3
RPLDEKDTSMKLWCA	SPAG9	676	O60271
WKEEDATLSSPAVVM	ALDH6A1	516	Q02252
MENSLRCVWVPKLAF	DCC	1	P43146
ADLSVCALWMPQEAV	GPR88	76	Q9GZN0
WSLKAAMPVEAKCIN	KLHL6	496	Q8WZ60
DIWPFIVISDDSCVM	GREB1	1636	Q4ZG55
ECVDHTPKLKLWMAA	GSTO1	191	P78417
EMWAELCPSAKGAII	NUDT22	266	Q9BRQ3
CVTLVWRMPDEDSKI	FSD1	181	Q9BTV5
VAMKCAIWLAEQRVP	RBCK1	26	Q9BYM8
SLLSDCMWETPIAQA	HERC1	1986	Q15751
IMDWRIKDCVDAPTQ	SLC43A1	376	O75387
VDWVEVDAPSLGKCM	LOXHD1	1051	Q8IVV2
KICSWSLDMLSHPQD	DYNC1I2	406	Q13409
SCGPMREFEIIWVTK	MAP3K8	221	P41279
AWCDRILMSPSAKEL	INPP5A	346	Q14642
LSEKPVCLQEIMTVW	KIAA0232	181	Q92628
LACLKVPEANSSWMD	DLAT	486	P10515
LMTACDLGAVTKPWE	PDE11A	811	Q9HCR9
MTACDLSAITKPWEV	PDE6A	716	P16499
QSLPDHKWEMCTSID	FUCA1	286	P04066
WCKDILQTIMSFTPH	MED23	711	Q9ULK4
DDLPHWVLSAMKCLA	DEPDC1	241	Q5TB30
LTCSAILFKEWQDMP	NIPA2	261	Q8N8Q9
ETAWEAKAMAVIACL	KNTC1	776	P50748
LRNETWEDLPKMSCT	KCNU1	6	A8MYU2
WEDLPKMSCTTEIQA	KCNU1	11	A8MYU2
VCWHPEETFKLMVAE	NUP37	171	Q8NFH4
TWTPLEAKCRDFENM	PAXBP1	636	Q9Y5B6
VRTKPGCSMLEIWDV	DPY19L2	706	Q6NUT2
VSWCKVEAMALKPDL	POLA1	511	P09884
KVLTCAAVWRMPKEL	EIPR1	91	Q53HC9
DWTELTNCVPAIMEK	HS6ST3	211	Q8IZP7
CAVPWDILKASMNTS	LRRC8B	66	Q6P9F7
VPWIEDCKAKMSELR	MACF1	4921	Q9UPN3
FDWLDNTVIKLCTMP	MACF1	6126	Q9UPN3
MEIPTTIQCDLCLKW	MORC2	491	Q9Y6X9
TAMLWCELSKVAPVE	OBSCN	3466	Q5VST9
PAERSPLMCVLKEAW	SMPD2	296	O60906
VWVCSTDMLLSVPAN	FCSK	146	Q8N0W3
EAMTAIAEACMLPWT	CKAP5	701	Q14008
IAEACMLPWTAEQVV	CKAP5	706	Q14008
MTATRLLWDDPECEI	HDAC10	11	Q969S8
DVAMWARKNPVVLFC	GPR135	456	Q8IZ08
EIPEKIWSSMEASQC	COG1	126	Q8WTW3
SWMPTLEKICEEVIV	DNAH3	3586	Q8TD57
KDTSAILDMKWCHIP	DPH7	86	Q9BTV6
CLWEKLPTSMKRVAE	POLQ	671	O75417
HLATSWMPTLEKVCE	DNAH7	3491	Q8WXX0
WMPTLEKVCEELSPE	DNAH7	3496	Q8WXX0
FMVKVWDPETETCLH	FBXW7	521	Q969H0
KAEVCMAVPWLSLQR	CYP11B1	6	P15538
DWKDISVPTLLCMGD	CALHM4	271	Q5JW98
AMPCKSAEWLQEELE	DUSP7	51	Q16829
PKAVVAFCLMWTIAI	CNR1	231	P21554
CPDWVLAEISTLAKM	COMMD4	11	Q9H0A8
WTEFVDMKVHVPCET	FKTN	401	O75072
SLVQWEMEVCKLPRL	MARK1	751	Q9P0L2
VQWEMEVCKLPRLSL	MARK2	746	Q7KZI7
VQWEMEVCKLPRLSL	MARK3	711	P27448
MALRAKAEVCVAAPW	CYP11B2	1	P19099
SVFPSTIVMEWDLVC	SLC22A20P	116	A6NK97
CVVFSEAPKSWMVRE	SLFN13	321	Q68D06
ECVTEGIWKFPIMLI	CFAP47	3016	Q6ZTR5
FLKQCLEWDPAVRMT	DYRK2	511	Q92630
VDVTLMPIDCELSSW	C8B	56	P07358
CEMPSLSRKNDLIIW	ERCC6L	356	Q2NKX8
PMRLESFSACIWVKA	PTX3	201	P26022
CSAVSWEELKAMDLP	MAP3K4	596	Q9Y6R4
CLESDPKMRWTASQL	MAP3K4	1581	Q9Y6R4
PADIWSLGCTIIEMA	MAP3K15	831	Q6ZN16
MWKDIPSSIAFECTQ	NRK	1496	Q7Z2Y5
AAPWIPDKATDICMR	PLEKHF1	146	Q96S99
VCISDLRIPLMWKDT	RTKN	121	Q9BST9
DILALVMKTCEWLPS	PSAPL1	86	Q6NUJ1
VMKTCEWLPSQESSA	PSAPL1	91	Q6NUJ1
CVHLTPKEFLIWTMD	THADA	1626	Q6YHU6
LEAGCQAWDTKPSIM	SUPT20HL1	341	Q3ZLR7
KCLSIMLAEWEANPL	RPAIN	121	Q86UA6
WLIECIRAGKPVEMT	DNTT	106	P04053
TEMCPKSEDVWLEAA	PRPF6	336	O94906
FMTLWKVELDCISVL	PTCHD1	741	Q96NR3
AEWDHLKISIPMCLS	GANAB	621	Q14697
LACEIKVLHMEPWSS	TFB2M	256	Q9H5Q4
MDVLPSHCWISEMVV	KITLG	61	P21583
CPREIISLMKLCWEA	RIPK1	256	Q13546
ISLMKLCWEANPEAR	RIPK1	261	Q13546
DWGENMVSKSIPVLC	APEH	211	P13798
CLPDLSVWAEMLDKS	APEH	641	P13798
LAKAWLPEVMILVCD	AAGAB	101	Q6PD74
TKWDMVRKLVPSCDQ	ACTN3	616	Q08043
VSTECLMTRPWVCSK	CLEC2L	196	P0C7M8
PSLTCVMEGKDIEDW	CLEC4C	66	Q8WTT0
TDVSRKCWMFETQPL	XIRP2	661	A4UGR9
KCWMFETQPLDILKE	XIRP2	666	A4UGR9
RMFLENETWELCPVK	VPS50	461	Q96JG6
TSLEQEKEPWNMKIC	ZNF714	26	Q96N38
RDWLDCSSMEIKPNV	SUPT3H	201	O75486
KLMRWTPAAADICFT	TAFAZZIN	91	Q16635
EGLKELMQLCWSSEP	RIPK3	256	Q9Y572
PEETWVAETLCGLKM	SPDYE3	291	A6NKU9
MSCRAWVSPEELEEI	SPDYE7P	176	Q495Y7
TACKLLNITADPMDW	SPDEF	136	O95238
VVAERVPWEKMCETL	STAT6	441	P42226
MDAVPLLKTVCDWRN	TMTC2	296	Q8N394
KMHITLCDFIVPWDT	TIMP2	121	P16035
EKWGTLTDCVVMRDP	HNRNPA3	56	P51991
MLNPCSTKIWFVIEL	SUCO	341	Q9UBS9
IDCSMVQVRGKEDPW	TIMM17A	76	Q99595
LEPWLIKEMDACLSD	YTHDC2	461	Q9H6S0
EIFTCMEGWKDLPAT	ZNF548	151	Q8NEK5
KSLNWEEMEKSRCIP	PSMG2	156	Q969U7
KEIHWPSTALKMEEC	SEMA3E	91	O15041
ADACIHSWKIPDLSM	STRN4	511	Q9NRL3
WVLFPDVCMVIASEI	TAPT1	336	Q6NXT6
MWSTVKEPLDTTLCF	USP34	296	Q70CQ2
WLGVPSQDKMEIRSC	XPO6	76	Q96QU8
VPECLKVWDRFLSTM	UBR4	776	Q5T4S7
SVLLCNVKDWMDPSE	TG	1756	P01266
ITELLQMCWPSLSED	ZFYVE26	1061	Q68DK2
WLFETCPMSELAEKQ	XIRP1	596	Q702N8
ICKAMETWLSADPQH	TNS2	211	Q63HR2
TINVKELCEPCWKLM	TSC2	246	P49815
KAMAPVLSDVTVEWI	VWA5B1	531	Q5TIE3
TICLSKMDIAWVILA	TMEM108	461	Q6UXF1
EMVRWLVSCATEIGP	ZSWIM4	691	Q9H7M6
QLKEMAPAIDWLSCL	KEL	306	P23276
LSTRCWEMPENLSTK	MYT1	636	Q01538