Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	KDEL sequence binding	KDELR2 KDELR3 KDELR1	4.07e-07	3	149	3	GO:0005046
GeneOntologyMolecularFunction	ATP-dependent activity	ABCA1 ABCA2 ABCA3 ATP7B MYO1A MYO7A TMEM94 HSPH1 SRCAP DNAH7 ABCA9 ATP2C1 ENTPD2 CCT8 KIF5A KIF5C POLQ	3.49e-06	614	149	17	GO:0140657
GeneOntologyMolecularFunction	ER retention sequence binding	KDELR2 KDELR3 KDELR1	4.03e-06	5	149	3	GO:0046923
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA1 ABCA2 ABCA3 ATP7B TMEM94 ABCA9 ATP2C1	1.76e-05	109	149	7	GO:0042626
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCA1 ABCA2 ABCA3 ATP7B SRCAP DNAH7 ABCA9 ATP2C1 ENTPD2 CCT8 KIF5A KIF5C POLQ	2.74e-05	441	149	13	GO:0016887
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ABCA1 ABCA2 ABCA3 ATP7B SRCAP DNAH7 ABCA9 ATP2C1 ENTPD2 CCT8 GNB4 KIF5A KIF5C GNB1 POLQ ARL14	2.27e-04	775	149	16	GO:0017111
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO1A MYO7A DNAH7 KIF5A KIF5C MYO16	2.59e-04	118	149	6	GO:0003774
GeneOntologyMolecularFunction	sphingolipid floppase activity	ABCA1 ABCA2	3.29e-04	4	149	2	GO:0046623
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ABCA1 ABCA2 ABCA3 ATP7B TMEM94 ABCA9 ATP2C1	3.85e-04	178	149	7	GO:0015399
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA1 ABCA2 ABCA3 ABCA9	4.86e-04	49	149	4	GO:0140359
GeneOntologyMolecularFunction	pyrophosphatase activity	ABCA1 ABCA2 ABCA3 ATP7B SRCAP DNAH7 ABCA9 ATP2C1 ENTPD2 CCT8 GNB4 KIF5A KIF5C GNB1 POLQ ARL14	5.43e-04	839	149	16	GO:0016462
GeneOntologyMolecularFunction	collagen binding involved in cell-matrix adhesion	ITGA11 ITGA10	5.45e-04	5	149	2	GO:0098639
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ABCA1 ABCA2 ABCA3 ATP7B SRCAP DNAH7 ABCA9 ATP2C1 ENTPD2 CCT8 GNB4 KIF5A KIF5C GNB1 POLQ ARL14	5.50e-04	840	149	16	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ABCA1 ABCA2 ABCA3 ATP7B SRCAP DNAH7 ABCA9 ATP2C1 ENTPD2 CCT8 GNB4 KIF5A KIF5C GNB1 POLQ ARL14	5.50e-04	840	149	16	GO:0016818
GeneOntologyMolecularFunction	DNA-directed DNA polymerase activity	TENT4B REV3L POLQ	8.30e-04	25	149	3	GO:0003887
GeneOntologyMolecularFunction	active transmembrane transporter activity	ABCA1 ABCA2 ABCA3 ATP7B TMEM94 SLC6A19 SLC28A3 ABCA9 ATP2C1 SLC30A5 SLC12A1	9.24e-04	477	149	11	GO:0022804
GeneOntologyMolecularFunction	cholesterol binding	NPC1 GPR155 ABCA1 SULT2B1	9.24e-04	58	149	4	GO:0015485
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ABCA1 ABCA2 ABCA3	1.16e-03	28	149	3	GO:0140326
GeneOntologyCellularComponent	Golgi-associated vesicle membrane	KDELR2 KDELR3 PI4KA KDELR1 AP1G2	7.90e-05	61	151	5	GO:0030660
Domain	ER_ret_rcpt	KDELR2 KDELR3 KDELR1	4.98e-07	3	149	3	IPR000133
Domain	ER_lumen_recept	KDELR2 KDELR3 KDELR1	4.98e-07	3	149	3	PF00810
Domain	ER_LUMEN_RECEPTOR_1	KDELR2 KDELR3 KDELR1	4.98e-07	3	149	3	PS00951
Domain	ER_LUMEN_RECEPTOR_2	KDELR2 KDELR3 KDELR1	4.98e-07	3	149	3	PS00952
Domain	ABC_A	ABCA1 ABCA2 ABCA3 ABCA9	1.83e-06	12	149	4	IPR026082
Domain	Quinoprotein_ADH-like_supfam	FAM234B CFAP251 EML4 AASDH EML1	6.37e-05	53	149	5	IPR011047
Domain	DUF1908	MAST4 MAST1	3.75e-04	4	149	2	PF08926
Domain	MA_Ser/Thr_Kinase_dom	MAST4 MAST1	3.75e-04	4	149	2	IPR015022
Domain	MAST_pre-PK_dom	MAST4 MAST1	3.75e-04	4	149	2	IPR023142
Domain	-	MAST4 MAST1	3.75e-04	4	149	2	1.20.1480.20
Domain	ABC_tran	ABCA1 ABCA2 ABCA3 ABCA9	5.76e-04	48	149	4	PF00005
Domain	ABC_TRANSPORTER_2	ABCA1 ABCA2 ABCA3 ABCA9	5.76e-04	48	149	4	PS50893
Domain	Guanine_nucleotide-bd_bsu	GNB4 GNB1	6.22e-04	5	149	2	IPR016346
Domain	ABC_TRANSPORTER_1	ABCA1 ABCA2 ABCA3 ABCA9	6.24e-04	49	149	4	PS00211
Domain	WD40_repeat_dom	KNTC1 CFAP251 EML4 DMXL1 GNB4 EML1 GNB1 WDR49 FBXW7	6.44e-04	297	149	9	IPR017986
Domain	ABC_transporter-like	ABCA1 ABCA2 ABCA3 ABCA9	6.74e-04	50	149	4	IPR003439
Domain	Znf_C2H2_jaz	HIVEP2 PRDM10 ZNF638	6.86e-04	22	149	3	IPR022755
Domain	zf-C2H2_jaz	HIVEP2 PRDM10 ZNF638	6.86e-04	22	149	3	PF12171
Domain	HELP	EML4 EML1	9.29e-04	6	149	2	PF03451
Domain	-	FAM234B AASDH	9.29e-04	6	149	2	2.140.10.10
Domain	Quinoprotein_ADH-like_fam	FAM234B AASDH	9.29e-04	6	149	2	IPR027295
Domain	HELP	EML4 EML1	9.29e-04	6	149	2	IPR005108
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NPC1 FOXO3 ABCA2 HIVEP2 MYO7A TMEM94 RAP1GAP2 REV3L SRCAP ADCY9 DIP2A FAT1 HEG1 KLHL25 PI4KA RRP12 ENTPD2 ZNF516 MAD1L1 C19orf44 PDCD11 AP1G2 GCN1	6.65e-10	1105	153	23	35748872
Pubmed	Cell-type-specific differences in KDEL receptor clustering in mammalian cells.	KDELR2 KDELR3 KDELR1	8.35e-08	3	153	3	32645101
Pubmed	A molecular specificity code for the three mammalian KDEL receptors.	KDELR2 KDELR3 KDELR1	8.35e-08	3	153	3	18086916
Pubmed	The dynamic organisation of the secretory pathway.	KDELR2 KDELR3 KDELR1	8.35e-08	3	153	3	9118249
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	TENT4B DSG2 MUC16 RICTOR ERBIN DNAH7 ADCY9 DMXL1 FAT1 SLC30A5 PI4KA ZNF638 CCT8 PCCB GCN1 ARL14	3.69e-07	777	153	16	35844135
Pubmed	Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation.	DSG2 PECAM1 CDH2	2.88e-06	7	153	3	15479741
Pubmed	Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.	ABCA1 ABCA2 ABCA3	4.60e-06	8	153	3	24293640
Pubmed	BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.	RANBP2 DSG2 HSPH1 DBNL ERBIN SLC30A5 CCT8 GCN1	5.56e-06	216	153	8	31519766
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KDELR2 KNTC1 KDELR3 RANBP2 MYO1A ACTBL2 HSPH1 DBNL STOX1 PFKM SRCAP ERBIN LUZP1 ENTPD2 KDELR1 KIF5A KIF5C GNB1 POLQ MNDA	5.74e-06	1442	153	20	35575683
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RANBP2 ARHGAP24 GRM5 ERBIN LUZP1 PI4KA ZNF516 MAD1L1 CCT8 KIF5A KIF5C EML1 SPATS2 GNB1 CDH2 WNK3	5.87e-06	963	153	16	28671696
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	FOXO3 RANBP2 DSG2 HSPH1 DBNL CPD PFKM DNAH7 LUZP1 MAST4 CPNE3 CCT8 KIF5C GNB1 PCCB	5.96e-06	853	153	15	28718761
Pubmed	Widespread and dynamic translational control of red blood cell development.	RAB11FIP2 XPNPEP1 AWAT2 PI4KA MAD1L1 WNK3	6.25e-06	102	153	6	27899360
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	FOXO3 PDE3B HIVEP2 DSG2 RAB11FIP2 DBNL RICTOR ERBIN DNAH7 LUZP1 MAST4 PI4KA MAD1L1 KIF5C WNK3	6.66e-06	861	153	15	36931259
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FOXO3 KDELR2 PDE3B HIVEP2 ABHD2 SLC22A23 LAMA3 CPD ZSWIM1 ERBIN ATP2C1 PTPRE HPN MAD1L1 ZNF638 MAST1 XYLB KIF5C SPATS2 STX17	9.18e-06	1489	153	20	28611215
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	MUC16 XPNPEP1 DNAH7 FAT1 MAD1L1 CDH2 HYDIN	1.10e-05	170	153	7	23314748
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RANBP2 ACTBL2 XPO4 RICTOR CPD ERBIN ADCY9 LUZP1 PTPRE PI4KA RRP12 ZNF638 GNB4 STX17 GCN1 FBXW7	1.69e-05	1049	153	16	27880917
Pubmed	The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium.	KIF5A KIF5C CDH2	1.78e-05	12	153	3	15834408
Pubmed	Impaired pancreatic development in Hif2-alpha deficient mice.	PECAM1 ARNT EPAS1	1.78e-05	12	153	3	20678473
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	DSG2 TMEM94 RAB11FIP2 RICTOR CPD ERBIN ADCY9 SLC30A5 PI4KA CDH2	1.87e-05	421	153	10	36976175
Pubmed	Endothelial PAS domain protein 1 gene promotes angiogenesis through the transactivation of both vascular endothelial growth factor and its receptor, Flt-1.	ARNT EPAS1	1.92e-05	2	153	2	15192019
Pubmed	Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization.	ARNT EPAS1	1.92e-05	2	153	2	16181639
Pubmed	ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease.	ABCA1 ABCA2	1.92e-05	2	153	2	15649702
Pubmed	A novel conserved targeting motif found in ABCA transporters mediates trafficking to early post-Golgi compartments.	ABCA1 ABCA3	1.92e-05	2	153	2	21586796
Pubmed	Increased Expression of the ABCA1 and ABCA3 Transporter Genes is Associated with Cisplatin Resistance in Breast Cancer Cells.	ABCA1 ABCA3	1.92e-05	2	153	2	38019257
Pubmed	Mutant POLQ and POLZ/REV3L DNA polymerases may contribute to the favorable survival of patients with tumors with POLE mutations outside the exonuclease domain.	REV3L POLQ	1.92e-05	2	153	2	32838755
Pubmed	ABC transporters: from microorganisms to man.	ABCA1 ABCA2	1.92e-05	2	153	2	1282354
Pubmed	New approach to capture and characterize synaptic proteome.	KIF5A KIF5C	1.92e-05	2	153	2	25352669
Pubmed	Knockdown of REV3 synergizes with ATR inhibition to promote apoptosis induced by cisplatin in lung cancer cells.	ATR REV3L	1.92e-05	2	153	2	28075014
Pubmed	Cloning, characterization and tissue distribution of the rat ATP-binding cassette (ABC) transporter ABC2/ABCA2.	ABCA1 ABCA2	1.92e-05	2	153	2	10970803
Pubmed	Allosteric inhibition of hypoxia inducible factor-2 with small molecules.	ARNT EPAS1	1.92e-05	2	153	2	23434853
Pubmed	A Golgi-based KDELR-dependent signalling pathway controls extracellular matrix degradation.	KDELR2 KDELR1	1.92e-05	2	153	2	25682866
Pubmed	Cloning of two novel ABC transporters mapping on human chromosome 9.	ABCA1 ABCA2	1.92e-05	2	153	2	8088782
Pubmed	Expression of the lipid transporters ABCA3 and ABCA1 is diminished in human breast cancer tissue.	ABCA1 ABCA3	1.92e-05	2	153	2	19902402
Pubmed	HIF-1beta determines ABCA1 expression under hypoxia in human macrophages.	ABCA1 ARNT	1.92e-05	2	153	2	19828131
Pubmed	The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling.	PECAM1 EPAS1	1.92e-05	2	153	2	10880563
Pubmed	Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.	ARNT EPAS1	1.92e-05	2	153	2	19129502
Pubmed	ARNT-deficient mice and placental differentiation.	PECAM1 ARNT	1.92e-05	2	153	2	9398442
Pubmed	KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover.	KDELR2 KDELR1	1.92e-05	2	153	2	30760704
Pubmed	Rictor/mammalian target of rapamycin 2 regulates the development of Notch1 induced murine T-cell acute lymphoblastic leukemia via forkhead box O3.	FOXO3 RICTOR	1.92e-05	2	153	2	25201756
Pubmed	Desmoglein-2 interaction is crucial for cardiomyocyte cohesion and function.	DSG2 CDH2	1.92e-05	2	153	2	25213555
Pubmed	Epistasis between intracellular cholesterol trafficking-related genes (NPC1 and ABCA1) and Alzheimer's disease risk.	NPC1 ABCA1	1.92e-05	2	153	2	20571217
Pubmed	ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity.	NPC1 ABCA1	1.92e-05	2	153	2	12215451
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	HSPH1 RAB11FIP2 DBNL STOX1 ERBIN LUZP1 MAST1 SPATS2 GNB1 CDH2	2.24e-05	430	153	10	32581705
Pubmed	Desmoglein 2 regulates cardiogenesis by restricting hematopoiesis in the developing murine heart.	DSG2 PECAM1 CDH2	2.31e-05	13	153	3	34737300
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RANBP2 EML4 HSPH1 DBNL RICTOR PFKM SRCAP ERBIN LUZP1 POLR3A PI4KA RRP12 CPNE3 ZNF638 CCT8 PDCD11 AP1G2 GCN1	3.02e-05	1353	153	18	29467282
Pubmed	Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.	KNTC1 TMEM94 DIP2A PDCD11	3.21e-05	41	153	4	8724849
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	NPC1 RANBP2 CPD RRP12 ZNF638 PDCD11 GCN1	3.33e-05	202	153	7	24639526
Pubmed	CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.	MYO1A DSG2 ACTBL2 HSPH1 CPNE3 CCT8 GNB4 GNB1	4.40e-05	288	153	8	31501420
Pubmed	Self-organization of MTOCs replaces centrosome function during acentrosomal spindle assembly in live mouse oocytes.	KIF5A KIF5C	5.75e-05	3	153	2	17693257
Pubmed	Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation.	ARNT EPAS1	5.75e-05	3	153	2	21814490
Pubmed	Hepatic Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) regulates metabolism in mice.	ARNT EPAS1	5.75e-05	3	153	2	29190746
Pubmed	Coiled-coil coactivators play a structural role mediating interactions in hypoxia-inducible factor heterodimerization.	ARNT EPAS1	5.75e-05	3	153	2	25627682
Pubmed	Cloning and localization of a conventional kinesin motor expressed exclusively in neurons.	KIF5A KIF5C	5.75e-05	3	153	2	7514426
Pubmed	Altered DNA binding specificity of Arnt by selection of partner bHLH-PAS proteins.	ARNT EPAS1	5.75e-05	3	153	2	15190133
Pubmed	ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein.	NPC1 ABCA1	5.75e-05	3	153	2	22179027
Pubmed	The ancient regulatory-protein family of WD-repeat proteins.	CFAP251 WDR49	5.75e-05	3	153	2	8090199
Pubmed	Structural basis for PAS domain heterodimerization in the basic helix--loop--helix-PAS transcription factor hypoxia-inducible factor.	ARNT EPAS1	5.75e-05	3	153	2	14668441
Pubmed	A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells.	ARNT EPAS1	5.75e-05	3	153	2	23796364
Pubmed	Preferential binding of a kinesin-1 motor to GTP-tubulin-rich microtubules underlies polarized vesicle transport.	KIF5A KIF5C	5.75e-05	3	153	2	21768290
Pubmed	Hypoxia-inducible factors regulate filaggrin expression and epidermal barrier function.	ARNT EPAS1	5.75e-05	3	153	2	24999590
Pubmed	Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons.	KIF5A KIF5C	5.75e-05	3	153	2	30068641
Pubmed	Differential regulation of ATP binding cassette protein A1 expression and ApoA-I lipidation by Niemann-Pick type C1 in murine hepatocytes and macrophages.	NPC1 ABCA1	5.75e-05	3	153	2	17553802
Pubmed	The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability.	ARNT EPAS1	5.75e-05	3	153	2	25855602
Pubmed	N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis.	PECAM1 CDH2	5.75e-05	3	153	2	15809310
Pubmed	Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha.	PECAM1 ARNT	5.75e-05	3	153	2	9436976
Pubmed	Structural integration in hypoxia-inducible factors.	ARNT EPAS1	5.75e-05	3	153	2	26245371
Pubmed	The Wilson disease protein ATP7B resides in the late endosomes with Rab7 and the Niemann-Pick C1 protein.	NPC1 ATP7B	5.75e-05	3	153	2	15681833
Pubmed	Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells.	RICTOR FBXW7	5.75e-05	3	153	2	22285861
Pubmed	Inositol pyrophosphates promote MYC polyubiquitination by FBW7 to regulate cell survival.	IP6K1 FBXW7	5.75e-05	3	153	2	33821962
Pubmed	Activity of hypoxia-inducible factor 2alpha is regulated by association with the NF-kappaB essential modulator.	ARNT EPAS1	5.75e-05	3	153	2	15653678
Pubmed	Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells.	ARNT EPAS1	5.75e-05	3	153	2	9000051
Pubmed	Hypoxia-inducible factor-dependent production of profibrotic mediators by hypoxic hepatocytes.	ARNT EPAS1	5.75e-05	3	153	2	19302442
Pubmed	Examining the role of ABC lipid transporters in pulmonary lipid homeostasis and inflammation.	ABCA1 ABCA3	5.75e-05	3	153	2	28241820
Pubmed	Molecular imaging: into in vivo interaction of HIF-1alpha and HIF-2alpha with ARNT.	ARNT EPAS1	5.75e-05	3	153	2	19845609
Pubmed	Hypoxia-inducible factors in the kidney.	ARNT EPAS1	5.75e-05	3	153	2	16554418
Pubmed	Hypoxia-inducible factor regulates alphavbeta3 integrin cell surface expression.	ARNT EPAS1	5.75e-05	3	153	2	15689487
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	RANBP2 REV3L ZNF644 ZNF516 PDCD11 POLQ LRIF1	6.05e-05	222	153	7	37071664
Pubmed	Human transcription factor protein interaction networks.	NR2C1 ACTR8 HSPH1 SRCAP ERBIN SETDB1 FAT1 ARNT ZNF644 RRP12 ZNF516 UBXN7 ZNF638 PDCD11 GNB4 PCCB LRIF1 FBXW7	6.11e-05	1429	153	18	35140242
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	ABCA2 ACTBL2 HSPH1 RICTOR XPNPEP1 SRCAP CPNE3 CCT8 EML1 PCCB GCN1 HYDIN MYO16	6.25e-05	807	153	13	30575818
Pubmed	A human MAP kinase interactome.	RANBP2 HIVEP2 RAP1GAP2 LAMA3 ERBIN SETDB1 KIF5A COG5 GCN1 EPAS1	6.27e-05	486	153	10	20936779
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	KNTC1 AASDH SRCAP LUZP1 SETDB1 ARNT PI4KA ZNF644 ZNF516 CPNE3 LRIF1	6.31e-05	588	153	11	38580884
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	NPC1 FAM234B RANBP2 PDE3B DSG2 HSPH1 CPD ATP2C1 PI4KA RRP12 GNB1 COG5 GCN1 WNK3	7.66e-05	942	153	14	31073040
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	NPC1 KDELR3 FAM234B ITGA11 ABCA2 ATR DSG2 HSPH1 CPD DMXL1 FAT1 HEG1 RRP12 KDELR1 CCT8 CDH2	8.43e-05	1201	153	16	35696571
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TMEM94 RAP1GAP2 CSMD3 ERBIN SETDB1 ZNF644 RRP12 MAST1 ADGRL3	8.53e-05	407	153	9	12693553
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	NPC1 ABCA2 LAMA3 ERAP2 ENTPD2 CDH2	9.14e-05	164	153	6	32409323
Pubmed	Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation.	RAB11FIP2 AWAT2 MAD1L1 WNK3	1.03e-04	55	153	4	24200680
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	NR2C1 RANBP2 LUZP1 SETDB1 ZNF644 ZNF516 CCT8 PCCB GCN1	1.04e-04	418	153	9	34709266
Pubmed	A gain-of-function mutation in Tnni2 impeded bone development through increasing Hif3a expression in DA2B mice.	PECAM1 ARNT EPAS1	1.05e-04	21	153	3	25340332
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CFAP47 PDE3B MYO7A HSPH1 C11orf24 SLC28A3 STOX1 REV3L QRICH2 DIP2A PI4KA CCT8	1.08e-04	736	153	12	29676528
Pubmed	Functional comparison between secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and sarcoplasmic reticulum Ca2+-ATPase (SERCA) 1 isoforms by steady-state and transient kinetic analyses.	ABCA1 ATP2C1	1.15e-04	4	153	2	16192278
Pubmed	Correction of apolipoprotein A-I-mediated lipid efflux and high density lipoprotein particle formation in human Niemann-Pick type C disease fibroblasts.	NPC1 ABCA1	1.15e-04	4	153	2	17020879
Pubmed	BMP-2 and TGF-beta1 differentially control expression of type II procollagen and alpha 10 and alpha 11 integrins in mouse chondrocytes.	ITGA11 ITGA10	1.15e-04	4	153	2	20129696
Pubmed	Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization.	PECAM1 CDH2	1.15e-04	4	153	2	15371328
Pubmed	HIF-1 alpha is required for solid tumor formation and embryonic vascularization.	PECAM1 ARNT	1.15e-04	4	153	2	9606183
Pubmed	Involvement of vessels and PDGFB in muscle splitting during chick limb development.	PECAM1 EPAS1	1.15e-04	4	153	2	17553906
Pubmed	Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA.	GNB4 GNB1	1.15e-04	4	153	2	1543505
Pubmed	Hypoxia-induced mitogenic factor has antiapoptotic action and is upregulated in the developing lung: coexpression with hypoxia-inducible factor-2alpha.	ARNT EPAS1	1.15e-04	4	153	2	15117738
Pubmed	GRIP1 interlinks N-cadherin and AMPA receptors at vesicles to promote combined cargo transport into dendrites.	KIF5C CDH2	1.15e-04	4	153	2	24639525
Pubmed	The role of G protein beta subunits in the release of ATP from human erythrocytes.	GNB4 GNB1	1.15e-04	4	153	2	12512701
Pubmed	The action of HIF-3α variants on HIF-2α-HIF-1β heterodimer formation is directly probed in live cells.	ARNT EPAS1	1.15e-04	4	153	2	26160453
Interaction	OPALIN interactions	KDELR2 KNTC1 KDELR3 ATR XPO4 DIP2A ATP2C1 SLC30A5 PI4KA KDELR1 GCN1	5.19e-07	209	151	11	int:OPALIN
Cytoband	1q21	ACP6 ITGA10 SETDB1 ARNT	2.53e-04	91	153	4	1q21
Cytoband	9q31.1	ABCA1 GRIN3A STX17	3.53e-04	41	153	3	9q31.1
Cytoband	18q11.2	NPC1 LAMA3 CDH2	5.28e-04	47	153	3	18q11.2
GeneFamily	ATP binding cassette subfamily A	ABCA1 ABCA2 ABCA3 ABCA9	9.15e-07	14	102	4	805
GeneFamily	WD repeat domain containing	CFAP251 EML4 DMXL1 GNB4 EML1 GNB1 WDR49 FBXW7	1.18e-04	262	102	8	362
Coexpression	HALLMARK_BILE_ACID_METABOLISM	NPC1 ABCA1 ABCA2 ABCA3 PFKM ABCA9 SULT2B1	4.00e-06	112	151	7	M5948
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	FOXO3 RANBP2 HIVEP2 ATR REV3L ADCY9 SETDB1 FAT1 HEG1 ATP2C1 MAD1L1 UBXN7 ZNF638 KIF5C COG5 CDH2 MNAT1	9.49e-06	856	151	17	M4500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN	RANBP2 ADCY9 HEG1 ATP2C1 UBXN7 CDH2	9.95e-06	85	151	6	M10575
Coexpression	GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP	ACP6 PDE3B RPS6KB2 PECAM1 GSAP PTPRE TLR1 CPNE3	2.11e-05	199	151	8	M9754
Coexpression	GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_UP	ABCA1 PDE3B HIVEP2 PECAM1 PTPRE TLR1 GNB4 EPAS1	2.18e-05	200	151	8	M9737
Coexpression	GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP	GPR155 FAM234B ABCA3 SLC22A23 HSPH1 XPNPEP1 HPN STX17	2.18e-05	200	151	8	M7525
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	GPR155 ABCA3 ARHGAP24 MYO7A RAP1GAP2 LAMA3 RICTOR REV3L GRM5 CSMD3 MAST4 ERAP2 MAST1 KIF5C GRIN3A HYDIN WNK3 ADGRL3	7.09e-05	1106	151	18	M39071
Coexpression	GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN	RAP1GAP2 CPD GSAP F10 HEG1 HPN TLR1	7.75e-05	177	151	7	M7637
Coexpression	GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_UP	SCFD2 GPR155 RAP1GAP2 TLR1 ZC3H12D AP1G2 FBXW7	8.03e-05	178	151	7	M383
Coexpression	ENK_UV_RESPONSE_KERATINOCYTE_DN	FOXO3 RANBP2 ATR CPD PFKM ADCY9 FAT1 ATP2C1 CPNE3 ZNF638 COG5	1.14e-04	481	151	11	M3898
Coexpression	LU_EZH2_TARGETS_DN	NPC1 NR2C1 FAM234B DSG2 RAB11FIP2 HEG1 ATP2C1 PTPRE PI4KA POLQ	1.14e-04	400	151	10	M2140
Coexpression	NAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_UP	KDELR2 C11orf24 FAM200B POLR3A SLC30A5 MAD1L1 KDELR1 ZNF638 PDCD11 SPATS2 GCN1 FBXW7	1.27e-04	573	151	12	M41006
Coexpression	ZHONG_PFC_C3_MICROGLIA	C2orf69 ABCA2 RAP1GAP2 CSMD3 POLR3A MAST4 UBXN7 MAST1 CDH2 MYO16 FBXW7	1.29e-04	488	151	11	M39104
Coexpression	GSE25088_WT_VS_STAT6_KO_MACROPHAGE_UP	GALC SLC22A23 XPO4 GSAP PFKM PANK1 F10	1.46e-04	196	151	7	M7973
Coexpression	GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN	NPC1 ACTR8 ABHD2 PRDM10 HEG1 PTPRE KIR3DS1	1.51e-04	197	151	7	M4421
Coexpression	GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN	GALC RAB11FIP2 RAP1GAP2 GSAP ERBIN CPNE3 LRIF1	1.56e-04	198	151	7	M3248
Coexpression	GSE22886_NAIVE_TCELL_VS_NKCELL_DN	NPC1 ACTR8 ABHD2 PRDM10 HEG1 PTPRE KIR3DS1	1.56e-04	198	151	7	M4415
Coexpression	GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_DN	KDELR2 ACOT13 RPS6KB2 KDELR1 SPATS2 PCCB GCN1	1.56e-04	198	151	7	M4441
Coexpression	GSE17721_CTRL_VS_PAM3CSK4_12H_BMDC_DN	CPD KLHL25 PTPRE RRP12 MAST1 TSHZ1 SPATS2	1.61e-04	199	151	7	M3750
Coexpression	GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_DN	KDELR2 KDELR3 PDE3B PECAM1 CPNE3 CDH2 MNDA	1.61e-04	199	151	7	M5201
Coexpression	GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN	NPC1 FOXO3 ABCA2 ADCY9 ARNT HEG1 PTPRE	1.61e-04	199	151	7	M6519
Coexpression	GSE40685_NAIVE_CD4_TCELL_VS_TREG_DN	ACP6 HIVEP2 PFKM LUZP1 PTPRE AP3M2 WNK3	1.66e-04	200	151	7	M9303
Coexpression	GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_UP	SLC6A19 RAP1GAP2 STOX1 ZSWIM1 LUZP1 KLHL25 KIF5C	1.66e-04	200	151	7	M7198
Coexpression	GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_DN	FOXO3 ABCA1 HIVEP2 RICTOR GSAP STX17 EPAS1	1.66e-04	200	151	7	M5724
Coexpression	GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN	FAM234B ABCA1 HIVEP2 RAB11FIP2 CPD KLHL25 ZNF644	1.66e-04	200	151	7	M5679
Coexpression	GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_UP	C11orf24 GSAP MS4A7 F10 PTPRE AP3M2 TSHZ1	1.66e-04	200	151	7	M4393
Coexpression	GSE19825_IL2RALOW_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_DN	NR2C1 FAM234B HSPH1 DIP2A SLC30A5 RRP12 PDCD11	1.66e-04	200	151	7	M4302
Coexpression	FEVR_CTNNB1_TARGETS_UP	KDELR3 ABCA3 DSG2 MYO7A ABHD2 SLC22A23 LAMA3 C11orf24 SLC28A3 IP6K1 PTPRE SULT2B1 AP3M2	1.83e-04	688	151	13	M2342
Coexpression	DAZARD_UV_RESPONSE_CLUSTER_G6	FOXO3 REV3L ADCY9 FAT1 MAST4 ZNF638	1.99e-04	145	151	6	M1810
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_1000	GALC DSG2 RAB11FIP2 REV3L CSMD3 PANK1 DNAH7 SLC30A5 TSHZ1 ADGRL3	1.43e-05	259	148	10	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k1_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#2_top-relative-expression-ranked_200	DMXL1 HEG1 MAST4 CPNE3	1.81e-05	23	148	4	gudmap_developingGonad_e18.5_epididymis_200_k2
CoexpressionAtlas	dev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500	GALC DSG2 RAB11FIP2 GSAP REV3L PANK1 DNAH7 SLC30A5 TAF7L TSHZ1 WNK3 ADGRL3	2.72e-05	404	148	12	gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_500
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#1_top-relative-expression-ranked_500	RAB11FIP2 PANK1 SLC30A5 TAF7L TSHZ1 ADGRL3	4.24e-05	91	148	6	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k1_500
CoexpressionAtlas	B cells, B.T3.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23+, Spleen, avg-3	GPR155 ABCA1 ARHGAP24 HIVEP2 EML4 PECAM1 DMXL1 HEG1 MAST4 TLR1 ZC3H12D	4.72e-05	361	148	11	GSM538219_500
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_500	SRCAP DMXL1 HEG1 MAST4 CPNE3 CDH2	1.05e-04	107	148	6	gudmap_developingGonad_e14.5_ epididymis_500_k2
CoexpressionAtlas	CD positive, CD19 Control, 19+ 4- 8-, Spleen, avg-6	GPR155 ABCA1 ARHGAP24 EML4 PECAM1 DMXL1 HEG1 MAST4 TLR1 ZC3H12D	1.37e-04	339	148	10	GSM403988_500
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000	NPC1 GALC DSG2 RAB11FIP2 REV3L CSMD3 PANK1 DNAH7 SLC30A5 TAF7L CPNE3 TSHZ1 STX17 CDH2 WNK3 ADGRL3	1.57e-04	803	148	16	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_1000
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FAM234B PRDM10 BPI AP3M2 XYLB KIF5A ADGRL3	3.10e-07	129	152	7	2f30b4897343586c9b49a1d2bec3007ec737085c
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	RANBP2 PDE3B HIVEP2 EML4 RICTOR ZC3H12D AP3M2	1.12e-06	156	152	7	1545169694f686d28648a68b552c2ae606599d66
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP24 ATP7B SLC22A23 PTPRE ZNF516 C19orf44 SPATS2	1.56e-06	164	152	7	0853e75b60b2a78257b660910c3ee15b09c5f5b0
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	ABCA1 SLC22A23 LAMA3 HEG1 PTPRE EPAS1 MYO16	1.98e-06	170	152	7	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	Ciliated_cells-A-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	CFAP47 CFAP251 STOX1 MS4A7 DNAH7 SULT2B1 HYDIN	2.50e-06	176	152	7	1c364155f46b9a7c995bdc2cc2333c437cd90f5b
ToppCell	Adult-Epithelial-ciliated_cell-D122\|Adult / Lineage, Cell type, age group and donor	CFAP47 CFAP251 GRM5 DNAH7 MDH1B WDR49 HYDIN	3.12e-06	182	152	7	7ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPS1 CSMD3 FAT1 KIF5A HYDIN MYO16 ADGRL3	3.35e-06	184	152	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPS1 CSMD3 FAT1 KIF5A HYDIN MYO16 ADGRL3	3.35e-06	184	152	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPS1 CSMD3 FAT1 KIF5A HYDIN MYO16 ADGRL3	3.35e-06	184	152	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	CFAP47 CFAP251 STOX1 GRM5 DNAH7 WDR49 HYDIN	3.47e-06	185	152	7	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	COVID-19-kidney-Stressed_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	GPR155 HSPH1 PANK1 KLHL25 MAST4 XYLB CDH2	3.73e-06	187	152	7	acd305475f3609800af0d7bc68d83ef41228080b
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RANBP2 PDE3B EML4 HSPH1 RICTOR ATP2C1 ZNF644	3.86e-06	188	152	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Control-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	PDE3B PECAM1 ITGA10 FAT1 EML1 EPAS1 ADGRL3	3.86e-06	188	152	7	88b3415e33db81726dd29c1f50c886e057af50a0
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 ARHGAP24 SLC22A23 LAMA3 SLC28A3 GSAP MAST4	3.86e-06	188	152	7	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	Ciliated\|World / shred by cell class for parenchyma	CFAP251 STOX1 MS4A7 DNAH7 MDH1B WDR49 HYDIN	4.00e-06	189	152	7	711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RANBP2 PDE3B EML4 HSPH1 RRP12 ZC3H12D AP3M2	4.43e-06	192	152	7	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3B PECAM1 LUZP1 HEG1 EML1 EPAS1 ADGRL3	4.59e-06	193	152	7	a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 CFAP251 STOX1 DNAH7 MDH1B WDR49 HYDIN	4.74e-06	194	152	7	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MUC16 FAM135B ENTPD2 KIF5A HYDIN WNK3 ADGRL3	4.74e-06	194	152	7	2dcc3b99dbedaf8a6916891c85091ddb79d7ee31
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 CFAP251 MUC16 DNAH7 MDH1B WDR49 HYDIN	4.74e-06	194	152	7	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KDELR2 KDELR3 PECAM1 C11orf24 ZNF215 KDELR1 SPATS2	4.91e-06	195	152	7	fb3d6a3b10aedc7fdd9789b2c47b4e80fa8e411f
ToppCell	Caecum-T_cell-Tfh\|T_cell / Region, Cell class and subclass	RAP1GAP2 CPS1 ABCA9 TLR1 AP3M2 PCCB MYO16	5.07e-06	196	152	7	fe2ee5788028e6b671674f0cc50e2b6379f50976
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 CFAP251 MUC16 DNAH7 MDH1B WDR49 HYDIN	5.61e-06	199	152	7	2498237b9e895ca4826a3378d9d40989968df72b
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 CFAP251 MUC16 DNAH7 MDH1B WDR49 HYDIN	5.61e-06	199	152	7	542ec45c931b40738df1f3777b00c83be33a514a
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 CFAP251 STOX1 DNAH7 MDH1B WDR49 HYDIN	5.79e-06	200	152	7	926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFAP47 CFAP251 STOX1 DNAH7 MDH1B WDR49 HYDIN	5.79e-06	200	152	7	f1a49bc818054fb0734d3b84725ee6487b034567
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Ciliated\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CFAP47 CFAP251 STOX1 DNAH7 MDH1B WDR49 HYDIN	5.79e-06	200	152	7	d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 CFAP251 STOX1 DNAH7 MDH1B WDR49 HYDIN	5.79e-06	200	152	7	06ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFAP47 CFAP251 STOX1 DNAH7 MDH1B WDR49 HYDIN	5.79e-06	200	152	7	cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCell	343B-Myeloid-Dendritic-cDC1\|343B / Donor, Lineage, Cell class and subclass (all cells)	FAM135B PTPRE TLR1 CPNE3 CDH2 MNDA	1.20e-05	148	152	6	e44cdc1c3f3314c549a0afa9298c8568022b9d8b
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	CFAP47 MUC16 STOX1 DNAH7 WDR49 HYDIN	1.34e-05	151	152	6	8216462e723fec2797387929dde095370947e10a
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-Tfh\|Liver / Manually curated celltypes from each tissue	GPR155 ABCA3 PANK1 ZC3H12D KIF5C TRAV40	1.61e-05	156	152	6	85bc34ff507f9a66c6e3ba7a3ffd5416d0073ccf
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KNTC1 PDE3B XPO4 MS4A7 ABCA9 AP1G2	1.80e-05	159	152	6	c0e55f25271f788c08fa4b95186501fc27b2ec39
ToppCell	Ciliated_cells-B-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	CFAP47 CFAP251 STOX1 MS4A7 DNAH7 HYDIN	2.14e-05	164	152	6	fd30c55d0d75ef8b9396435d836187168095152b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDE3B HIVEP2 HSPH1 ZC3H12D AP3M2 KIF5A	2.37e-05	167	152	6	ced6ed9b412739c6ced622523347c10295edbf53
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP251 MUC16 GRM5 DNAH7 WDR49 HYDIN	2.53e-05	169	152	6	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RANBP2 PDE3B EML4 HSPH1 ZC3H12D AP3M2	2.71e-05	171	152	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SCFD2 CFAP251 PECAM1 FAM200A MDH1B AP3M2	2.80e-05	172	152	6	d65ffff3e341af34a043a0d802d7ba4b69de36e9
ToppCell	Ciliated_cells-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	CFAP251 MUC16 MS4A7 DNAH7 MDH1B HYDIN	2.80e-05	172	152	6	187ae91148d293537afc77e10da2b64302322224
ToppCell	PND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ABCA1 GALC MS4A7 ABCA9 TLR1 MNDA	2.80e-05	172	152	6	9a659442dc41bd2a4361a7e38a7ee37a39781667
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC22A23 GRM5 FAT1 CDH2 HYDIN ADGRL3	3.18e-05	176	152	6	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP47 DSG2 MYO7A SLC28A3 MDH1B HYDIN	3.28e-05	177	152	6	e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCell	Ciliated_cells-B-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	CFAP251 STOX1 MS4A7 DNAH7 MDH1B HYDIN	3.28e-05	177	152	6	c38138fb5ad9766c2d240811210c854338cd612e
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP47 CFAP251 STOX1 DNAH7 MDH1B WDR49	3.39e-05	178	152	6	de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 LAMA3 SLC28A3 GSAP MAST4 HPN	3.50e-05	179	152	6	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPR155 SLC6A19 CYP4A22 HPN XYLB CDH2	3.50e-05	179	152	6	78fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCA2 DSG2 TMEM94 CPD LUZP1 PTPRE	3.72e-05	181	152	6	12ff56fa2949c8d53360cdf2cacfd326e65b54aa
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A23 SLC28A3 FAT1 CPT1C ENTPD2 MAST1	3.72e-05	181	152	6	35eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A23 SLC28A3 FAT1 CPT1C ENTPD2 MAST1	3.72e-05	181	152	6	e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP47 CFAP251 STOX1 DNAH7 WDR49 HYDIN	3.72e-05	181	152	6	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	RANBP2 PDE3B EML4 ZC3H12D AP3M2 EML1	3.72e-05	181	152	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	Ciliated_cells-A-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CFAP251 MUC16 MS4A7 DNAH7 MDH1B HYDIN	4.08e-05	184	152	6	07c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFAP47 CFAP251 GRM5 DNAH7 MDH1B HYDIN	4.08e-05	184	152	6	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	ILEUM-non-inflamed-(5)_IgG_plasma_cells\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	KDELR2 C11orf24 ZNF215 KDELR1 SPATS2 FBXW7	4.20e-05	185	152	6	93b9a47357152ea95dfdfe8e7d111906a4adc551
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 CFAP251 DNAH7 MDH1B WDR49 HYDIN	4.20e-05	185	152	6	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CFAP251 MUC16 MS4A7 DNAH7 MDH1B HYDIN	4.20e-05	185	152	6	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFAP47 RAP1GAP2 CPS1 FAM135B HPN ARL14	4.20e-05	185	152	6	d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	CFAP47 CFAP251 MUC16 DNAH7 WDR49 HYDIN	4.20e-05	185	152	6	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP251 STOX1 DNAH7 MDH1B WDR49 HYDIN	4.33e-05	186	152	6	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 CFAP251 DNAH7 MDH1B WDR49 HYDIN	4.33e-05	186	152	6	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	390C-Epithelial_cells-Epithelial-F_(Ciliated)\|390C / Donor, Lineage, Cell class and subclass (all cells)	CFAP47 CFAP251 STOX1 DNAH7 WDR49 HYDIN	4.33e-05	186	152	6	708c5edefe36c91df27cf53c1b5101fb2030cc5a
ToppCell	390C-Epithelial_cells-Epithelial-F_(Ciliated)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	CFAP47 CFAP251 STOX1 DNAH7 WDR49 HYDIN	4.33e-05	186	152	6	029390c4aaf64e6bcd86124cd4a6dd2e6f3a374b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC22A23 SLC6A19 ADCY9 MAST4 HPN XYLB	4.33e-05	186	152	6	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	ADCY9 FAT1 MAST4 HPN XYLB CDH2	4.46e-05	187	152	6	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	PECAM1 ITGA10 FAT1 CPT1C EML1 EPAS1	4.46e-05	187	152	6	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDE3B PECAM1 ITGA10 EML1 EPAS1 ADGRL3	4.46e-05	187	152	6	97b2463fb37e7196dd2f92553acf8e7bc3ec40dd
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	NPC1 ABCA3 HIVEP2 EML4 ACOT13 MAST4	4.46e-05	187	152	6	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	KDELR2 KNTC1 KDELR3 ZNF215 SPATS2 FBXW7	4.60e-05	188	152	6	c7b1807c96f87fbcd37739a159cf00f9a1ff5d71
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3B PECAM1 HEG1 EML1 EPAS1 ADGRL3	4.60e-05	188	152	6	73f6ec915934154f435a376cb274b058ff7c5f35
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	CFAP47 CFAP251 DNAH7 MDH1B WDR49 HYDIN	4.60e-05	188	152	6	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOXO3 ITGA10 REV3L FAM135B PTPRE ADGRL3	4.60e-05	188	152	6	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFAP47 CFAP251 GRM5 DNAH7 MDH1B HYDIN	4.60e-05	188	152	6	2b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCell	(7)_Epithelial-F_(Ciliated)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CFAP251 STOX1 MS4A7 DNAH7 MDH1B HYDIN	4.60e-05	188	152	6	9a8b9f745eed9f129b6c582f48fbbaaacbebb4b3
ToppCell	COVID-19-lung-Ciliated\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFAP47 CFAP251 DNAH7 MDH1B WDR49 HYDIN	4.73e-05	189	152	6	a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GRM5 DNAH7 FAT1 CDH2 HYDIN ADGRL3	4.73e-05	189	152	6	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 RAP1GAP2 LAMA3 GSAP KIF5C WDR49	4.73e-05	189	152	6	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDELR3 ARHGAP24 C11orf24 MS4A7 KDELR1 STX17	4.73e-05	189	152	6	e11998c57609c5714705713ac3a32016d6d841dd
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	CFAP47 CFAP251 DNAH7 MDH1B WDR49 HYDIN	4.73e-05	189	152	6	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	CFAP47 CFAP251 DNAH7 MDH1B WDR49 HYDIN	4.73e-05	189	152	6	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NR2C1 FAM234B PECAM1 RAP1GAP2 SRCAP ZC3H12D	4.87e-05	190	152	6	63018acb7ad80415e861643162abdc2e55968ee4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP24 RAP1GAP2 CPD DNAH7 SLC12A1 HYDIN	4.87e-05	190	152	6	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3B PECAM1 HEG1 EML1 EPAS1 ADGRL3	4.87e-05	190	152	6	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	Bronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GPR155 ABCA3 RAP1GAP2 ABCA9 ENTPD2	4.89e-05	116	152	5	b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	CFAP47 CFAP251 DNAH7 MDH1B WDR49 HYDIN	5.02e-05	191	152	6	8a5a2188b13ef4bbfd626a42565566708a751c1b
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 RAP1GAP2 GSAP DNAH7 KIF5C WDR49	5.02e-05	191	152	6	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PECAM1 ITGA10 LUZP1 EML1 EPAS1 ADGRL3	5.02e-05	191	152	6	1de0bdfd13bd930691564c2673f2e66393bc0255
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)\|356C / Donor, Lineage, Cell class and subclass (all cells)	CFAP47 CFAP251 DNAH7 MDH1B WDR49 HYDIN	5.02e-05	191	152	6	e314dd8f1a841cab847ae3703bedfe1bc623ac61
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFAP47 CFAP251 MUC16 DNAH7 WDR49 HYDIN	5.02e-05	191	152	6	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFAP47 CFAP251 MUC16 DNAH7 WDR49 HYDIN	5.02e-05	191	152	6	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFAP47 CFAP251 MUC16 DNAH7 WDR49 HYDIN	5.02e-05	191	152	6	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3B PECAM1 HEG1 EML1 EPAS1 ADGRL3	5.17e-05	192	152	6	c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PECAM1 ITGA10 LAMA3 HEG1 PTPRE EPAS1	5.17e-05	192	152	6	3259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCell	LPS-antiTNF-Endothelial-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3B PECAM1 HEG1 EML1 EPAS1 ADGRL3	5.32e-05	193	152	6	02f633b016ab19bfa65bfd0cf32f000549a62148
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3B PECAM1 HEG1 MAST4 EPAS1 ADGRL3	5.32e-05	193	152	6	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	C2orf69 RANBP2 PDE3B ACTR8 ATR CPD	5.32e-05	193	152	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 CFAP251 STOX1 DNAH7 WDR49 HYDIN	5.32e-05	193	152	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	HIVEP2 EML4 HSPH1 IP6K1 LUZP1 KLHL25	5.32e-05	193	152	6	dbf0fe496254320c894568c31e5f9ce63707d1b5
ToppCell	LPS-antiTNF-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3B PECAM1 HEG1 EML1 EPAS1 ADGRL3	5.32e-05	193	152	6	5122b1ffba42de190061be34ecdc6176f84e56a3
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDE3B HIVEP2 EML4 ZC3H12D AP3M2 KIF5C	5.32e-05	193	152	6	194b49c152e3e3f599068ec88a7f0af6427b743a
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SLC28A3 BPI CPNE3 GNB4 POLQ MNDA	5.32e-05	193	152	6	ccab6a0c76f574ef7e1d6d5f1e620376daf21bbf
Drug	Cefoxitin sodium salt [33564-30-6]; Up 200; 8.8uM; PC3; HT_HG-U133A	ABCA1 ITGA10 SETDB1 ARNT SLC30A5 MAST4 ERAP2 AP1G2 XYLB KIF5C	8.15e-07	197	151	10	7148_UP
Drug	Procyclidine hydrochloride [1508-76-5]; Up 200; 12.4uM; HL60; HT_HG-U133A	ABCA1 ABCA2 ABHD2 SRCAP ADCY9 RRP12 KIF5C CDH2 EPAS1	6.93e-06	197	151	9	2991_UP
Drug	Clobetasol propionate [25122-46-7]; Up 200; 8.6uM; PC3; HT_HG-U133A	FAM234B ABCA1 MAB21L4 ARNT KLHL25 TAF7L MNDA ADGRL3 FBXW7	6.93e-06	197	151	9	4497_UP
Drug	orthovanadate	ACP6 ABCA1 PDE3B ATP7B MYO7A ACTBL2 RPS6KB2 GRM5 ADCY9 ARNT ATP2C1 ENTPD2 KIF5A	6.96e-06	435	151	13	CID000061672
Drug	Verteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A	NPC1 FAM234B GALC DSG2 CPD ADCY9 FAT1 ATP2C1	1.24e-05	161	151	8	3556_DN
Disease	spinal muscular atrophy (implicated_via_orthology)	ATP7B KIF5A KIF5C	1.02e-05	9	148	3	DOID:12377 (implicated_via_orthology)
Disease	pigment dispersion syndrome, pigmentary glaucoma	GSAP GRM5	7.47e-05	3	148	2	EFO_0021425, MONDO_0010896
Disease	Colorectal Neoplasms	ABCA1 ABCA3 ATP7B ABCA9 FAT1 ARNT SULT2B1 GNB4	8.27e-05	277	148	8	C0009404
Disease	reaction time measurement	FOXO3 GPR155 C2orf69 EML4 RAP1GAP2 SLC28A3 BPI ZNF638 TSHZ1 GRIN3A CDH2 EPAS1	1.27e-04	658	148	12	EFO_0008393
Disease	Adenoid Cystic Carcinoma	FOXO3 SRCAP ERBIN FAT1 FBXW7	1.52e-04	100	148	5	C0010606
Disease	visceral adipose tissue measurement	NPC1 FOXO3 KNTC1 ABCA1 HIVEP2 ADCY9 HEG1 EML1 MNAT1 WDR49	1.66e-04	481	148	10	EFO_0004765
Disease	lung small cell carcinoma (is_implicated_in)	LAMA3 RICTOR FAT1	3.69e-04	28	148	3	DOID:5409 (is_implicated_in)
Disease	Squamous cell carcinoma of lung	ATR MAST4 WNK3	5.51e-04	32	148	3	C0149782
Disease	longevity	NPC1 FOXO3 PFKM SLC12A1 ZNF516 MAD1L1 ADGRL3	5.99e-04	284	148	7	EFO_0004300
Disease	skin pigmentation measurement	RAB11FIP2 GRM5 SLC12A1 TSHZ1 HYDIN	6.52e-04	137	148	5	EFO_0007009
Disease	glycosyl-N-(2-hydroxynervonoyl)-sphingosine (d18:1/24:1(2OH)) measurement	CPS1 PRDM10	6.86e-04	8	148	2	EFO_0800533
Disease	serum albumin measurement	FAM234B CYP19A1 SLC28A3 IP6K1 ABCA9 ADCY9 ARNT CPT1C HPN MAD1L1	8.42e-04	592	148	10	EFO_0004535
Disease	Colorectal Carcinoma	ABCA1 ABCA3 ATP7B CSMD3 ABCA9 FAT1 ARNT SULT2B1 GNB4 WDR49 FBXW7	8.61e-04	702	148	11	C0009402
Disease	asthma, sex interaction measurement	RAB11FIP2 RAP1GAP2	8.79e-04	9	148	2	EFO_0008343, MONDO_0004979
Disease	2R,3R-dihydroxybutyrate measurement	MAB21L4 CPS1	8.79e-04	9	148	2	EFO_0800314
Disease	hair colour measurement, eye colour measurement, skin pigmentation measurement	RAB11FIP2 GRM5	1.10e-03	10	148	2	EFO_0007009, EFO_0007822, EFO_0009764
Disease	endometriosis, unipolar depression	HIVEP2 IP6K1 GRM5	1.32e-03	43	148	3	EFO_0001065, EFO_0003761
Disease	electrocardiography	ARHGAP24 SLC22A23 XPO4 LUZP1 MAST4 COG5 CDH2 WDR49 EPAS1	1.47e-03	530	148	9	EFO_0004327
Disease	urinary metabolite measurement	MAB21L4 RICTOR CPS1 FAM200B XYLB MYO16	1.52e-03	245	148	6	EFO_0005116
Disease	motor neuron disease (implicated_via_orthology)	KIF5A KIF5C	1.60e-03	12	148	2	DOID:231 (implicated_via_orthology)
Disease	caudate nucleus measurement, functional brain measurement, response to reward	CSMD3 FAM135B MYO16	1.71e-03	47	148	3	EFO_0007849, EFO_0008387, EFO_0008396
Disease	gallstones	KDELR2 KDELR3 CPS1 RRP12	2.17e-03	108	148	4	EFO_0004210
Disease	Childhood Acute Lymphoblastic Leukemia	ARNT GNB1 FBXW7	2.28e-03	52	148	3	C0023452
Disease	coronary artery disease	NPC1 KDELR2 NR2C1 ABCA1 HIVEP2 PECAM1 DMXL1 MAST4 MAD1L1 ZC3H12D EML1 COG5 PCCB ADGRL3	2.80e-03	1194	148	14	EFO_0001645
Disease	partial epilepsy	ADCY9 ADGRL3	3.23e-03	17	148	2	EFO_0004263
Disease	high altitude adaptation	KNTC1 EPAS1	3.23e-03	17	148	2	EFO_0009105
Disease	Malignant neoplasm of endometrium	ATR FBXW7	3.63e-03	18	148	2	C0007103
Disease	Carcinoma in situ of endometrium	ATR FBXW7	3.63e-03	18	148	2	C0346191
Disease	mean corpuscular hemoglobin concentration	KNTC1 ATP7B ATR RPS6KB2 XPNPEP1 PFKM CPS1 ADCY9 DMXL1 ZNF638 MAST1 LRIF1 MYO16	3.84e-03	1105	148	13	EFO_0004528
Disease	sexual dimorphism measurement	NPC1 FOXO3 ABCA1 HIVEP2 CYP19A1 RPS6KB2 TECTB CPD ADCY9 SETDB1 ZNF638 GCN1 MNAT1	3.87e-03	1106	148	13	EFO_0021796
Disease	monocyte percentage of leukocytes	NPC1 KDELR2 MS4A7 ADCY9 BPI PI4KA RRP12 ZNF516 COG5 MYO16	3.91e-03	731	148	10	EFO_0007989
Disease	Prostatic Neoplasms	ATP7B ATR CYP19A1 SETDB1 SULT2B1 HPN MAD1L1 CPNE3 KDELR1	4.01e-03	616	148	9	C0033578
Disease	Malignant neoplasm of prostate	ATP7B ATR CYP19A1 SETDB1 SULT2B1 HPN MAD1L1 CPNE3 KDELR1	4.01e-03	616	148	9	C0376358
Disease	citrulline measurement	CPS1 PTPRE	4.47e-03	20	148	2	EFO_0009777
Disease	phospholipids:total lipids ratio, intermediate density lipoprotein measurement	ABCA1 CPS1 PCCB	4.68e-03	67	148	3	EFO_0008595, EFO_0020946
Disease	schizophrenia (implicated_via_orthology)	HIVEP2 GRM5 CSMD3	4.88e-03	68	148	3	DOID:5419 (implicated_via_orthology)
Disease	Headache, HbA1c measurement	PFKM MAD1L1	4.93e-03	21	148	2	EFO_0004541, HP_0002315

Protein segments in the cluster

Peptide	Gene	Start	Entry
HGGLTATLVDNISTM	ACOT13	56	Q9NPJ3
VSHMKSLRGTGNTST	ARNT	136	P27540
SDGTATMTGKHSRVI	FAM200B	296	P0CF97
SVVKSHSITNMEIGG	ERBIN	866	Q96RT1
SKFMGLTQVELTGHS	EPAS1	116	Q99814
DKTTHLLGAFTGASM	CSMD3	1301	Q7Z407
GDLGMQVTSQIHFTK	C2orf69	356	Q8N8R5
TGHKMEFSGQIANLT	ADGRG4	2546	Q8IZF6
ESSGIHETTFNSIMK	ACTBL2	271	Q562R1
ATFGIVGQKMTTLQH	ACTR8	396	Q9H981
IKTVMFDKTGTITHG	ATP7B	1021	P35670
GHNGAGKSTTIKMIT	ABCA9	1326	Q8IUA7
GHRKFITMSDGATST	ABHD2	96	P08910
FLGHNGAGKTTTMSI	ABCA1	931	O95477
MGHGSTIQLSANTLK	ADGRL3	706	Q9HAR2
TLVTMGYSTEHSISG	AP1G2	226	O75843
GSHDLIGTFQTTMTK	CPNE3	221	O75131
GHNGAGKTTTLSMLT	ABCA3	566	Q99758
ASGTSLHQKAIMTFT	AASDH	656	Q4L235
LTGFVKSHMKSRGDT	ARL14	171	Q8N4G2
THMSLTGKSGLAGTI	DMXL1	1836	Q9Y485
SDGTANMTGKHSRLT	FAM200A	211	Q8TCP9
TKNEMTVTHIFTSDG	ATP2C1	356	P98194
FGNTMSGIHKSFEVL	CFAP251	1041	Q8TBY9
FTLGSEMKLHDSSGS	RANBP2	1821	P49792
EMKLHDSSGSQVGTG	RANBP2	1826	P49792
MEGSVHLITGDSSIN	NR2C1	346	P13056
ASQAGSETLMGFSKH	QRICH2	66	Q9H0J4
SETLMGFSKHGGFTS	QRICH2	71	Q9H0J4
SQGTHTFDPVTKMLS	AP3M2	326	P53677
MKGSSSASIVKGQHE	DSG2	696	Q14126
KGFQGTTQTSHGSLM	TENT4B	526	Q8NDF8
SIGSFVGMVTAHSQS	FAT1	1681	Q14517
SGQTDGLTFGHLKMV	MAB21L4	286	Q08AI8
VTEGFAHSKITTAMN	MUC16	4711	Q8WXI7
LQTMHGTTTHFDKIG	PTPRE	411	P23469
TVVRMHVGDGKSSSA	GRM5	841	P41594
SGSKMQLLETEFSHT	MAD1L1	671	Q9Y6D9
VTFSTGIKMGQHISL	MNAT1	221	P51948
MQTTSSRGLVFHTGT	LAMA3	3016	Q16787
SRGLVFHTGTKNSFM	LAMA3	3021	Q16787
QSHGVKIDGLTMQTF	LRIF1	136	Q5T3J3
MLTDVKHFLSSGGNV	MYO16	201	Q9Y6X6
HLSEMSSVGSKGDFL	MYO1A	956	Q9UBC5
MTKTLPTAVTHGFNS	GPR155	16	Q7Z3F1
QHTFKQEMTGVGASL	ENOX2	581	Q16206
THGIFTISTASMVEK	HSPH1	486	Q92598
GIVLDAGSSHTSMFI	ENTPD2	41	Q9Y5L3
QTMGVSHSFTPKGIT	MS4A7	6	Q9GZW8
FMISKTGEAETITTH	KDELR3	136	O43731
SKSGSHTVAVMNVGA	PFKM	396	P08237
HQMLKYVSTSESDGT	PDE3B	581	Q13370
ISGIHMQTSESTKSE	PECAM1	211	P16284
VTGTHKMLSAFNATS	FAM234B	226	A2RU67
VSGLSQHTGLAMATE	PI4KA	1091	P42356
FVFATSTTTTLGMHQ	KNTC1	1866	P50748
STTTTLGMHQLTFAH	KNTC1	1871	P50748
QTTTFTGHSGDVMSL	GNB4	176	Q9HAV0
DLLFHISGVTGKMTT	GCN1	1841	Q92616
GVMVQTSGKSHAASD	HEG1	141	Q9ULI3
SFGLEMSQTGFSSHV	ITGA11	361	Q9UKX5
NKGFISSTSLESHMK	PRDM10	566	Q9NQV6
TSFMGNKHIEDTGST	RICTOR	1161	Q6R327
FQAIKTHSEASGMVT	HPN	401	P05981
TSMGHIKLTDFGLSK	MAST1	506	Q9Y2H9
LKMTISQQEFGHTGL	PIPSL	746	A2A3N6
TETLQMGIKHFSGLF	GRIN3A	921	Q8TCU5
LAHMGSSVFSGITLT	NPC1	1191	O15118
QEELGGAKTHTTMSG	PCCB	241	P05166
RSSSLKVSGTKMGTH	ARHGAP24	461	Q8N264
KVSGTKMGTHSVQNG	ARHGAP24	466	Q8N264
DGMITFHISSKKSST	CPT1C	726	Q8TCG5
MHQEDFSGSLSSSGK	COG5	621	Q9UP83
TFTTSLENVGSHMTK	GSAP	321	A4D1B5
LENVGSHMTKGITFL	GSAP	326	A4D1B5
LMFVNVSGSHEAKGS	ATR	81	Q13535
FHGTSSRIGSSMKSV	CPS1	781	P31327
KDQLSQGTMHTGSTL	HYDIN	3861	Q4G0P3
SRSSTGSMNVTLFHK	KLHL25	11	Q9H0H3
SIDFLLTHKGTGNMV	AWAT2	166	Q6E213
GEETLIISKSSSMFH	CYP19A1	91	P11511
QTTTFTGHTGDVMSL	GNB1	176	P62873
ITGAFSNSVSLKMGH	C19orf44	316	Q9H6X5
SSLASLFLIGMHTTG	BPI	381	P17213
GTMKQSSDSHGVDIL	POLQ	1396	O75417
TIMKSAFSHQGSIQV	CYP4A22	196	Q5TCH4
VLSTTGHSTNFVIAM	DNAH7	3986	Q8WXX0
TLTGHQSLTSGMELK	FBXW7	576	Q969H0
MSTGSKKSLLSHEFQ	CPD	1351	O75976
SFLGHNGAGKTTTMS	ABCA2	1021	Q9BZC7
HTMGTTISGDNIGKN	ADGRF2	291	Q8IZF7
SRSTFLKVGQSIMHG	ADCY9	306	O60503
LTSGEVFGMHTEISI	MDH1B	151	Q5I0G3
HMGVSTDSGTQETKK	LUZP1	436	Q86V48
VTSMGHIKLTDFGLS	MAST4	701	O15021
SSFGLEMSQIGFSTH	ITGA10	366	O75578
MIISGTTAHFSSKDK	ERAP2	896	Q6P179
MLDGNSGLSSEKISH	IP6K1	166	Q92551
GQTSSGKTHTMEGKL	KIF5A	86	Q12840
DSHLISTGGKDTSIM	EML1	796	O00423
DSHLISTGGKDMSII	EML4	846	Q9HC35
VSTTGILAGVKMSHA	DIP2A	1156	Q14689
QELKAGTSIMGSHLT	FAM135B	1001	Q49AJ0
GTSIMGSHLTSAETF	FAM135B	1006	Q49AJ0
FMVSKTGEAETITSH	KDELR1	136	P24390
STLMTQKTGIVSGFG	F10	351	P00742
TLTLTIKGHFTSGML	GALC	631	P54803
SMHTVHLGVKGTSSL	CFAP47	2071	Q6ZTR5
FMISKTGEAETITTH	KDELR2	136	P33947
QEEGLHAGTMLTTFT	CDH2	506	P19022
VSTMASFLKGAHVTI	DBNL	101	Q9UJU6
IQMGSEKNFSSLHTT	PANK1	321	Q8TE04
LDKLSSMGHQATGTV	PGBD3	361	Q8N328
GLIAVMHTAGTFSLS	OR14A16	151	Q8NHC5
GKSTMFHATVASKTQ	MNDA	231	P41218
NMGLSESSSLGSAKH	FOXO3	556	O43524
LISSGMSSHKQGHTS	TAF7L	301	Q5H9L4
HQGLVSTLSTASMNG	SLC6A19	616	Q695T7
SLSGGISHNSMEVTK	RAP1GAP2	526	Q684P5
ALGSVVAHSTFSAMK	SULT2B1	236	O00204
GQTSSGKTHTMEGKL	KIF5C	86	O60282
MLSSQGHIKLTDFGL	RPS6KB2	201	Q9UBS0
SIVGMFASHAVGSLS	SLC22A23	541	A1A5C7
IHDGVSKANFSIGSM	KIR3DS1	171	Q14943
MATHGVKGTRTTSNN	POLR3A	1236	O14802
KDGSINTSQSMHVGE	SLC12A1	876	Q13621
VHVKNGSMGTFESQL	TECTB	141	Q96PL2
HMSSGLTDLLKTGFS	SCFD2	596	Q8WU76
TKSELHAIMTAGFST	SLC28A3	356	Q9HAS3
HAIMTAGFSTIAGSV	SLC28A3	361	Q9HAS3
TTTKETLATGHFMSV	SRCAP	876	Q6ZRS2
GGSKEATTTLHMLTL	RRP12	296	Q5JTH9
HLLFEFKGLMGTSTV	RRP12	926	Q5JTH9
SSQDLHKGTLSQMSG	SETDB1	176	Q15047
STHGIAIKSTNMASV	SETDB1	1171	Q15047
GNMSQLKFLGLSTTH	TLR1	136	Q15399
TKGTSAAHLNSMEVT	C11orf24	66	Q96F05
CGKGFTMKSTLSIHQ	ZNF615	601	Q8N8J6
TMKSTLSIHQQTHTG	ZNF615	606	Q8N8J6
HTLSIGDMVTGTVKS	PDCD11	1031	Q14690
VTSTELSSGDQSHKM	ZNF516	616	Q92618
NGVSDFETKSLTMHS	SPATS2	181	Q86XZ4
KDGTTDVTRTMHFGT	XPNPEP1	421	Q9NQW7
SKTSNIGLSMEFHGN	XPO4	171	Q9C0E2
STAQHVFKVSLVSGM	REV3L	96	O60673
KDTTTSTEQMLSHGT	TMEM94	691	Q12767
NSQGTSTDMLTIGHK	STOX1	391	Q6ZVD7
LTRSMTVGGAFHTTE	STX17	131	P56962
LAHSGVGSIIMSTDK	WDR49	416	Q8IV35
MSKTKILATGGASHN	XYLB	431	O75191
HETTLKGGMFAGQLT	ACP6	111	Q9NPH0
MSSEKLKAGTIGQTH	RAB11FIP2	236	Q7L804
GSNVAMSHGNKETFS	ZC3H12D	96	A2A288
TSDKMQHFKRTGTGT	ZNF644	1006	Q9H582
ILMFGGTSSNSVKQT	TRAV40	11	A0A0B4J280
SGLSTGFHDVLAMTK	SLC30A5	736	Q8TAD4
IFDMKSISGEESSHG	ZNF215	236	Q9UL58
TTITGASESVGKHML	UBXN7	21	O94888
KSTHLIGSGSEKMNI	ZSWIM1	351	Q9BR11
SAVIKMSTFGSHEGQ	HIVEP2	31	P31629
GISSSSVLHGMVFKK	CCT8	211	P50990
MVTGHFLKVTTSASK	TSHZ1	436	Q6ZSZ6
SVESGTKMSGLHISG	ZNF638	286	Q14966
QSAKMTSFGIEHISV	WNK3	1346	Q9BYP7
FDKVSSLGSGSDHVM	MYO7A	1306	Q13402