Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DENND5B SMAP1 GBP5 RAB3IP EIF2B5 NPRL3 SMAP2 DENND3	7.96e-05	507	56	8	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DENND5B SMAP1 GBP5 RAB3IP EIF2B5 NPRL3 SMAP2 DENND3	7.96e-05	507	56	8	GO:0030695
GeneOntologyMolecularFunction	enzyme regulator activity	DENND5B USP14 SMAP1 PPP3R2 GBP5 RAB3IP EIF2B5 NPRL3 MOB3B PPP1R9B SMAP2 DENND3	4.69e-04	1418	56	12	GO:0030234
GeneOntologyCellularComponent	NURF complex	RBBP4 RBBP7	1.52e-04	7	57	2	GO:0016589
GeneOntologyCellularComponent	sperm flagellum	CUL3 PPP3R2 MROH2B FLACC1 CFAP65	2.91e-04	214	57	5	GO:0036126
GeneOntologyCellularComponent	motile cilium	ADCY10 CUL3 PPP3R2 MROH2B FLACC1 CFAP65	4.02e-04	355	57	6	GO:0031514
GeneOntologyCellularComponent	9+2 motile cilium	CUL3 PPP3R2 MROH2B FLACC1 CFAP65	4.74e-04	238	57	5	GO:0097729
GeneOntologyCellularComponent	ISWI-type complex	RBBP4 RBBP7	6.51e-04	14	57	2	GO:0031010
GeneOntologyCellularComponent	sperm midpiece	PPP3R2 MROH2B CFAP65	7.12e-04	64	57	3	GO:0097225
GeneOntologyCellularComponent	CHD-type complex	RBBP4 RBBP7	9.68e-04	17	57	2	GO:0090545
GeneOntologyCellularComponent	ESC/E(Z) complex	RBBP4 RBBP7	9.68e-04	17	57	2	GO:0035098
GeneOntologyCellularComponent	NuRD complex	RBBP4 RBBP7	9.68e-04	17	57	2	GO:0016581
GeneOntologyCellularComponent	histone methyltransferase complex	KMT2C RBBP4 RBBP7	1.13e-03	75	57	3	GO:0035097
GeneOntologyCellularComponent	Sin3-type complex	RBBP4 RBBP7	1.63e-03	22	57	2	GO:0070822
Domain	CAF1C_H4-bd	RBBP4 RBBP7	2.37e-05	3	53	2	PF12265
Domain	Histone-bd_RBBP4_N	RBBP4 RBBP7	2.37e-05	3	53	2	IPR022052
Domain	ARM-type_fold	MON2 IPO8 PIK3C2G MROH2B EIF2B5 ZYG11B	3.83e-04	339	53	6	IPR016024
Domain	uDENN	DENND5B DENND3	8.10e-04	15	53	2	PF03456
Domain	UDENN	DENND5B DENND3	9.24e-04	16	53	2	PS50946
Domain	DDENN	DENND5B DENND3	9.24e-04	16	53	2	PS50947
Domain	DENN	DENND5B DENND3	9.24e-04	16	53	2	SM00799
Domain	dDENN	DENND5B DENND3	9.24e-04	16	53	2	SM00801
Domain	DENN	DENND5B DENND3	9.24e-04	16	53	2	PF02141
Domain	dDENN_dom	DENND5B DENND3	9.24e-04	16	53	2	IPR005112
Domain	uDENN_dom	DENND5B DENND3	9.24e-04	16	53	2	IPR005113
Domain	dDENN	DENND5B DENND3	9.24e-04	16	53	2	PF03455
Domain	DENN	DENND5B DENND3	9.24e-04	16	53	2	PS50211
Domain	DENN_dom	DENND5B DENND3	9.24e-04	16	53	2	IPR001194
Domain	Spectrin	SPTAN1 SYNE2	1.92e-03	23	53	2	PF00435
Domain	-	ADCY10 FICD NAA15 GTF3C3	2.81e-03	207	53	4	1.25.40.10
Domain	ArfGap	SMAP1 SMAP2	3.05e-03	29	53	2	SM00105
Domain	ArfGap	SMAP1 SMAP2	3.05e-03	29	53	2	PF01412
Domain	ARFGAP	SMAP1 SMAP2	3.05e-03	29	53	2	PS50115
Domain	Spectrin_repeat	SPTAN1 SYNE2	3.05e-03	29	53	2	IPR002017
Domain	ArfGAP	SMAP1 SMAP2	3.05e-03	29	53	2	IPR001164
Domain	-	MON2 IPO8 MROH2B ZYG11B	3.61e-03	222	53	4	1.25.10.10
Domain	Spectrin/alpha-actinin	SPTAN1 SYNE2	3.71e-03	32	53	2	IPR018159
Domain	SPEC	SPTAN1 SYNE2	3.71e-03	32	53	2	SM00150
Domain	TPR-like_helical_dom	ADCY10 FICD NAA15 GTF3C3	4.28e-03	233	53	4	IPR011990
Domain	Cadherin_tail	PCDHGB6 PCDHGA11	4.94e-03	37	53	2	PF15974
Domain	Cadherin_CBD	PCDHGB6 PCDHGA11	4.94e-03	37	53	2	IPR031904
Domain	Kinesin_motor_CS	KIF20A KIF4B	6.04e-03	41	53	2	IPR019821
Domain	Cadherin_C	PCDHGB6 PCDHGA11	6.33e-03	42	53	2	IPR032455
Domain	Cadherin_C_2	PCDHGB6 PCDHGA11	6.33e-03	42	53	2	PF16492
Domain	TPR_repeat	FICD NAA15 GTF3C3	6.38e-03	133	53	3	IPR019734
Domain	Kinesin-like_fam	KIF20A KIF4B	6.62e-03	43	53	2	IPR027640
Domain	KINESIN_MOTOR_1	KIF20A KIF4B	6.93e-03	44	53	2	PS00411
Domain	-	KIF20A KIF4B	6.93e-03	44	53	2	3.40.850.10
Domain	Kinesin_motor_dom	KIF20A KIF4B	6.93e-03	44	53	2	IPR001752
Domain	Kinesin	KIF20A KIF4B	6.93e-03	44	53	2	PF00225
Domain	KINESIN_MOTOR_2	KIF20A KIF4B	6.93e-03	44	53	2	PS50067
Domain	KISc	KIF20A KIF4B	6.93e-03	44	53	2	SM00129
Domain	ARM-like	MON2 IPO8 MROH2B ZYG11B	7.18e-03	270	53	4	IPR011989
Domain	TPR-contain_dom	FICD NAA15 GTF3C3	8.87e-03	150	53	3	IPR013026
Domain	TPR_2	NAA15 GTF3C3	8.87e-03	50	53	2	PF07719
Domain	TPR_2	NAA15 GTF3C3	8.87e-03	50	53	2	IPR013105
Pubmed	Interpreting the molecular mechanisms of RBBP4/7 and their roles in human diseases (Review).	RBBP4 RBBP7	2.64e-06	2	57	2	38577935
Pubmed	Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development.	RBBP4 RBBP7	2.64e-06	2	57	2	34709113
Pubmed	The Arf GTPase-activating protein SMAP1 promotes transferrin receptor endocytosis and interacts with SMAP2.	SMAP1 SMAP2	2.64e-06	2	57	2	25281535
Pubmed	Mice doubly-deficient in the Arf GAPs SMAP1 and SMAP2 exhibit embryonic lethality.	SMAP1 SMAP2	2.64e-06	2	57	2	26296315
Pubmed	Characterization of the gene encoding mouse retinoblastoma binding protein-7, a component of chromatin-remodeling complexes.	RBBP4 RBBP7	2.64e-06	2	57	2	12376095
Pubmed	The role of retinoblastoma-associated proteins 46 and 48 in estrogen receptor alpha mediated gene expression.	RBBP4 RBBP7	7.91e-06	3	57	2	18577416
Pubmed	Structural and biochemical characterization establishes a detailed understanding of KEAP1-CUL3 complex assembly.	CUL3 KLHL11	7.91e-06	3	57	2	37156295
Pubmed	Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases.	CUL3 KLHL11	7.91e-06	3	57	2	23349464
Pubmed	Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast.	RBBP4 RBBP7	7.91e-06	3	57	2	7503932
Pubmed	The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7.	RBBP4 RBBP7	7.91e-06	3	57	2	27144666
Pubmed	Ubiquitin Receptor Protein UBASH3B Drives Aurora B Recruitment to Mitotic Microtubules.	KIF20A CUL3	1.58e-05	4	57	2	26766443
Pubmed	Histone binding protein RbAp48 interacts with a complex of CREB binding protein and phosphorylated CREB.	RBBP4 RBBP7	1.58e-05	4	57	2	10866654
Pubmed	The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal.	KIF20A SYNE2	1.58e-05	4	57	2	33686165
Pubmed	Isolation of human NURF: a regulator of Engrailed gene expression.	RBBP4 RBBP7	1.58e-05	4	57	2	14609955
Pubmed	Identification of a genetic interaction between the tumor suppressor EAF2 and the retinoblastoma protein (Rb) signaling pathway in C. elegans and prostate cancer cells.	RBBP4 RBBP7	1.58e-05	4	57	2	24727455
Pubmed	Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells.	KIF20A IPO8 RBBP4 RBBP7	1.85e-05	95	57	4	29490077
Pubmed	Mrg15 stimulates Ash1 H3K36 methyltransferase activity and facilitates Ash1 Trithorax group protein function in Drosophila.	RBBP4 RBBP7	2.63e-05	5	57	2	29158494
Pubmed	MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex.	RBBP4 RBBP7	2.63e-05	5	57	2	10471499
Pubmed	Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.	DENND5B RAB3IP DENND3	3.12e-05	37	57	3	20937701
Pubmed	Functional and physical interaction between the histone methyl transferase Suv39H1 and histone deacetylases.	RBBP4 RBBP7	3.94e-05	6	57	2	11788710
Pubmed	SUMO modification enhances p66-mediated transcriptional repression of the Mi-2/NuRD complex.	RBBP4 RBBP7	3.94e-05	6	57	2	16738318
Pubmed	Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase.	RBBP4 RBBP7	3.94e-05	6	57	2	9427644
Pubmed	The structure of the core NuRD repression complex provides insights into its interaction with chromatin.	RBBP4 RBBP7	3.94e-05	6	57	2	27098840
Pubmed	CRL4(RBBP7) is required for efficient CENP-A deposition at centromeres.	RBBP4 RBBP7	3.94e-05	6	57	2	25795299
Pubmed	Expression, purification and characterization of the human MTA2-RBBP7 complex.	RBBP4 RBBP7	3.94e-05	6	57	2	28179136
Pubmed	BRCA1 interacts with components of the histone deacetylase complex.	RBBP4 RBBP7	3.94e-05	6	57	2	10220405
Pubmed	Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex.	RBBP4 RBBP7	5.51e-05	7	57	2	19686092
Pubmed	Smad-dependent recruitment of a histone deacetylase/Sin3A complex modulates the bone morphogenetic protein-dependent transcriptional repressor activity of Nkx3.2.	RBBP4 RBBP7	5.51e-05	7	57	2	14612411
Pubmed	CDK2AP1/DOC-1 is a bona fide subunit of the Mi-2/NuRD complex.	RBBP4 RBBP7	5.51e-05	7	57	2	20523938
Pubmed	Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein.	RBBP4 RBBP7	5.51e-05	7	57	2	12435631
Pubmed	Atypical Mowat-Wilson patient confirms the importance of the novel association between ZFHX1B/SIP1 and NuRD corepressor complex.	RBBP4 RBBP7	7.34e-05	8	57	2	18182442
Pubmed	Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation.	RBBP4 RBBP7	7.34e-05	8	57	2	20144788
Pubmed	The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes.	RBBP4 RBBP7	7.34e-05	8	57	2	11297506
Pubmed	Differential association of products of alternative transcripts of the candidate tumor suppressor ING1 with the mSin3/HDAC1 transcriptional corepressor complex.	RBBP4 RBBP7	7.34e-05	8	57	2	11118440
Pubmed	Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation.	RBBP4 RBBP7	7.34e-05	8	57	2	10471500
Pubmed	MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer.	RBBP4 RBBP7	7.34e-05	8	57	2	12705869
Pubmed	The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex.	RBBP4 RBBP7	7.34e-05	8	57	2	18067919
Pubmed	Identification and functional characterization of the p66/p68 components of the MeCP1 complex.	RBBP4 RBBP7	9.43e-05	9	57	2	11756549
Pubmed	RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest.	RBBP4 RBBP7	9.43e-05	9	57	2	11283269
Pubmed	Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex.	RBBP4 RBBP7	9.43e-05	9	57	2	9150135
Pubmed	Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity.	RBBP4 RBBP7	9.43e-05	9	57	2	23104054
Pubmed	RBB, a novel transcription repressor, represses the transcription of HDM2 oncogene.	RBBP4 RBBP7	9.43e-05	9	57	2	22926524
Pubmed	Identification of a nuclear domain with deacetylase activity.	RBBP4 RBBP7	9.43e-05	9	57	2	10984530
Pubmed	JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells.	RBBP4 RBBP7	9.43e-05	9	57	2	20075857
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	MON2 USP14 IPO8 RBBP4 RBBP7 SPTAN1 SYNE2 EIF2B5 UBE3C FAR1	1.05e-04	1440	57	10	30833792
Pubmed	SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.	CUL3 IPO8 RBBP7 GTF3C3	1.10e-04	150	57	4	30154076
Pubmed	ZIP: a novel transcription repressor, represses EGFR oncogene and suppresses breast carcinogenesis.	RBBP4 RBBP7	1.18e-04	10	57	2	19644445
Pubmed	Protein kinase CK2-mediated phosphorylation of HDAC2 regulates co-repressor formation, deacetylase activity and acetylation of HDAC2 by cigarette smoke and aldehydes.	RBBP4 RBBP7	1.18e-04	10	57	2	20388487
Pubmed	PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex.	RBBP4 RBBP7	1.18e-04	10	57	2	34180153
Pubmed	Identification of a novel BRMS1-homologue protein p40 as a component of the mSin3A/p33(ING1b)/HDAC1 deacetylase complex.	RBBP4 RBBP7	1.18e-04	10	57	2	15451426
Pubmed	Increased interaction between DJ-1 and the Mi-2/ nucleosome remodelling and deacetylase complex during cellular stress.	RBBP4 RBBP7	1.18e-04	10	57	2	20127688
Pubmed	BCL11B functionally associates with the NuRD complex in T lymphocytes to repress targeted promoter.	RBBP4 RBBP7	1.18e-04	10	57	2	16091750
Pubmed	EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells.	RBBP4 RBBP7	1.18e-04	10	57	2	31451685
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	KIF20A CUL3 DENND5B KMT2C IPO8 EIF2B5 ZYG11B	1.30e-04	689	57	7	36543142
Pubmed	Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes.	RBBP4 RBBP7	1.44e-04	11	57	2	29263092
Pubmed	MBD3L1 is a transcriptional repressor that interacts with methyl-CpG-binding protein 2 (MBD2) and components of the NuRD complex.	RBBP4 RBBP7	1.44e-04	11	57	2	15456747
Pubmed	Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal.	RBBP4 RBBP7	1.44e-04	11	57	2	22438827
Pubmed	Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.	KIF20A KIF4B	1.44e-04	11	57	2	15843429
Pubmed	Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c.	USP14 UBE3C	1.44e-04	11	57	2	28396413
Pubmed	The program for processing newly synthesized histones H3.1 and H4.	RBBP4 RBBP7	1.44e-04	11	57	2	20953179
Pubmed	An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting.	RBBP4 RBBP7	1.44e-04	11	57	2	23273982
Pubmed	Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses transcription.	RBBP4 RBBP7	1.44e-04	11	57	2	14581478
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	CUL3 USP14 RBBP4 RBBP7 SPTAN1 ZYG11B	1.58e-04	495	57	6	28581483
Pubmed	USP11 acts as a histone deubiquitinase functioning in chromatin reorganization during DNA repair.	RBBP4 RBBP7	1.72e-04	12	57	2	31504778
Pubmed	NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment.	RBBP4 RBBP7	1.72e-04	12	57	2	22560079
Pubmed	The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes.	RBBP4 RBBP7	1.72e-04	12	57	2	23708667
Pubmed	Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14.	RBBP4 RBBP7	1.72e-04	12	57	2	21937684
Pubmed	NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities.	RBBP4 RBBP7	1.72e-04	12	57	2	9885572
Pubmed	The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2.	RBBP4 RBBP7	2.03e-04	13	57	2	12124384
Pubmed	LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer.	RBBP4 RBBP7	2.03e-04	13	57	2	19703393
Pubmed	The metastasis-associated proteins 1 and 2 form distinct protein complexes with histone deacetylase activity.	RBBP4 RBBP7	2.03e-04	13	57	2	12920132
Pubmed	Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event.	RBBP4 RBBP7 SPTAN1 GADD45GIP1	2.31e-04	182	57	4	26527279
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	CUL3 IPO8 RBBP4 EIF2B5 UBE3C FAR1 GTF3C3	2.35e-04	759	57	7	35915203
Pubmed	MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.	RBBP4 RBBP7	2.37e-04	14	57	2	16428440
Pubmed	Identification of novel target genes specifically activated by deregulated E2F in human normal fibroblasts.	RBBP4 RBBP7	2.37e-04	14	57	2	26201719
Pubmed	NuRD-ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination.	RBBP4 RBBP7	2.37e-04	14	57	2	25150861
Pubmed	GATA-1 forms distinct activating and repressive complexes in erythroid cells.	RBBP4 RBBP7	2.37e-04	14	57	2	15920471
Pubmed	Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis.	RBBP4 RBBP7	2.73e-04	15	57	2	30135474
Pubmed	Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex.	RBBP4 RBBP7	2.73e-04	15	57	2	9804427
Pubmed	DLX1 and the NuRD complex cooperate in enhancer decommissioning and transcriptional repression.	RBBP4 RBBP7	2.73e-04	15	57	2	35695185
Pubmed	Codanin-1, mutated in the anaemic disease CDAI, regulates Asf1 function in S-phase histone supply.	RBBP4 RBBP7	2.73e-04	15	57	2	22407294
Pubmed	NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development.	RBBP4 RBBP7	2.73e-04	15	57	2	19927129
Pubmed	The chromatin remodeling factor CHD5 is a transcriptional repressor of WEE1.	RBBP4 RBBP7	2.73e-04	15	57	2	25247294
Pubmed	MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.	RBBP4 RBBP7	2.73e-04	15	57	2	15701600
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	USP14 KMT2C RBBP4 RBBP7 SPTAN1 GTF3C3	2.76e-04	549	57	6	38280479
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	MON2 CUL3 IPO8 TRAF3IP1 RAB3IP EIF2B5 ZYG11B PLEKHA7 SMAP2	2.79e-04	1321	57	9	27173435
Pubmed	RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation.	RBBP4 RBBP7	3.12e-04	16	57	2	30760870
Pubmed	Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1.	RBBP4 RBBP7	3.12e-04	16	57	2	11102443
Pubmed	Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1).	RBBP4 RBBP7	3.12e-04	16	57	2	11784859
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	KIF20A USP14 MIS18BP1 NAA15 RBBP4 SPTAN1 EIF2B5 FAR1 GTF3C3	3.32e-04	1353	57	9	29467282
Pubmed	Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.	IPO8 RBBP4 RBBP7	3.49e-04	83	57	3	20562864
Pubmed	Examining post-translational modification-mediated protein-protein interactions using a chemical proteomics approach.	RBBP4 RBBP7	3.53e-04	17	57	2	23281010
Pubmed	USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier.	RBBP4 RBBP7	3.97e-04	18	57	2	17846119
Pubmed	Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.	RBBP4 RBBP7	3.97e-04	18	57	2	10444591
Pubmed	The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities.	RBBP4 RBBP7	3.97e-04	18	57	2	9790534
Pubmed	A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes.	RBBP4 RBBP7	3.97e-04	18	57	2	12493763
Pubmed	Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.	RBBP4 RBBP7	3.97e-04	18	57	2	20064376
Pubmed	Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis.	RBBP4 RBBP7	3.97e-04	18	57	2	14645126
Pubmed	Human family with sequence similarity 60 member A (FAM60A) protein: a new subunit of the Sin3 deacetylase complex.	RBBP4 RBBP7	4.43e-04	19	57	2	22984288
Pubmed	Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.	RBBP4 RBBP7	4.43e-04	19	57	2	28554894
Interaction	FN3KRP interactions	KIF20A CUL3 RBBP4 RBBP7 UBE3C	5.16e-07	58	55	5	int:FN3KRP
Interaction	H4C3 interactions	CUL3 RBBP4 RBBP7 PPP1R9B	1.04e-05	50	55	4	int:H4C3
Interaction	EPOP interactions	CUL3 RBBP4 RBBP7 SPTAN1	1.22e-05	52	55	4	int:EPOP
Interaction	MIS18BP1 interactions	KIF20A CUL3 MIS18BP1 EIF2B5	2.79e-05	64	55	4	int:MIS18BP1
Interaction	GPHN interactions	CUL3 NAA15 SPTAN1 FADS2 PPP1R9B	3.21e-05	134	55	5	int:GPHN
Interaction	CBX5 interactions	KIF20A CUL3 USP14 MIS18BP1 IPO8 RBBP4 RBBP7	4.95e-05	356	55	7	int:CBX5
Interaction	SPTAN1 interactions	KIF20A MON2 CUL3 USP14 SPTAN1 SYNE2 PPP1R9B FLACC1	5.61e-05	496	55	8	int:SPTAN1
Interaction	ZNF827 interactions	RBBP4 RBBP7 UNC80	6.68e-05	29	55	3	int:ZNF827
Cytoband	12p11.21	DENND5B IPO8	3.44e-04	22	57	2	12p11.21
Cytoband	5q31	KIF20A PCDHGB6 PCDHGA11	4.06e-04	115	57	3	5q31
GeneFamily	Lysine methyltransferases\|Myb/SANT domain containing\|Polycomb repressive complex 2	RBBP4 RBBP7	6.76e-05	6	39	2	1347
GeneFamily	Histone deacetylases, class I\|EMSY complex\|NuRD complex\|SIN3 histone deacetylase complex	RBBP4 RBBP7	1.62e-04	9	39	2	1306
GeneFamily	PHD finger proteins\|NuRD complex	RBBP4 RBBP7	2.95e-04	12	39	2	1305
GeneFamily	Histone deacetylases, class I\|EMSY complex\|NuRD complex\|SIN3 histone deacetylase complex	RBBP4 RBBP7	2.95e-04	12	39	2	1243
GeneFamily	Guanylate cyclase receptors\|DENN/MADD domain containing	DENND5B DENND3	1.32e-03	25	39	2	504
GeneFamily	ArfGAPs	SMAP1 SMAP2	2.29e-03	33	39	2	395
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF20A KIF4B	4.42e-03	46	39	2	622
GeneFamily	Clustered protocadherins	PCDHGB6 PCDHGA11	8.40e-03	64	39	2	20
GeneFamily	WD repeat domain containing	RBBP4 RBBP7 DENND3	1.87e-02	262	39	3	362
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CUL3 GBP5 SPTAN1 SYNE2 ATP8B2	3.43e-06	180	57	5	6bb9f41c3a99d1bbe697f589fb2bcea9b7bfbeee
ToppCell	10x5'-blood-Lymphocytic_T_CD4-Tregs\|blood / Manually curated celltypes from each tissue	GBP5 SPTAN1 SYNE2 ANKDD1B ATP8B2	3.82e-06	184	57	5	22c15ce30171c687ab564f4383ae74d38b759272
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE SYNE2 MOB3B EVC PLEKHA7	4.94e-06	194	57	5	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	10x5'v1-week_17-19-Lymphocytic_B-B_lineage-pre_B_progenitor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MIS18BP1 RBBP4 RBBP7 SYNE2 GCSAM	5.59e-06	199	57	5	be425e9cb90a73289026b1b7cb581e1c02a8985e
ToppCell	10x5'v1-week_17-19-Lymphocytic_B-B_lineage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MIS18BP1 RBBP4 RBBP7 SYNE2 GCSAM	5.73e-06	200	57	5	c28d4ca51d2e2a3a22784ee251975f16a55b0297
ToppCell	10x5'v1-week_17-19-Lymphocytic_B\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MIS18BP1 RBBP4 RBBP7 SYNE2 GCSAM	5.73e-06	200	57	5	364f09eb9ae4913f5c80a29e943e1c0b2ffd5f93
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GBP5 SPTAN1 SYNE2 ATP8B2	2.33e-05	130	57	4	d47d4ff1263815896470d854d25306eb36919e70
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GBP5 SPTAN1 SYNE2 ATP8B2	2.33e-05	130	57	4	ad57b210c96caedadc1027b4d7a56b1bc389b137
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GBP5 SPTAN1 SYNE2 ATP8B2	4.41e-05	153	57	4	7480522a47e367f8facc4f5d599fbaf0b5ad4007
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GBP5 SPTAN1 SYNE2 ATP8B2	4.76e-05	156	57	4	53ded973358e3e48054130131e959f0d1f4ef60f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3C2G MOB3B KEL GCSAM	4.88e-05	157	57	4	2c5295043611bac7dfa4aef2146681bce4a33a8f
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE PIK3C2G RXFP2 UNC80	5.25e-05	160	57	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE PIK3C2G RXFP2 UNC80	5.25e-05	160	57	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GBP5 SPTAN1 SYNE2 ATP8B2	5.92e-05	165	57	4	9ccce713d4122054bf4bef4a7126d90cf9141b84
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GBP5 SPTAN1 SYNE2 ATP8B2	5.92e-05	165	57	4	dbe231d00843cae917efd1abea6079ace3b45cdf
ToppCell	Control-T_cells-Tregs\|Control / group, cell type (main and fine annotations)	GBP5 SYNE2 SMAP2 TRAV25	6.50e-05	169	57	4	e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Vcan_(SNc)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PCDHGB6 PIK3C2G RXFP2	6.59e-05	61	57	3	12de8c495c7f47ecd720f29a573471705603732a
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Vcan_(SNc)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PCDHGB6 PIK3C2G RXFP2	6.59e-05	61	57	3	a655232c6d92335eb086723ab9b05eb3a5479b68
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF20A MIS18BP1 ANGPT2 SYNE2	7.27e-05	174	57	4	9d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF20A MIS18BP1 ANGPT2 SYNE2	7.27e-05	174	57	4	53cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCell	Healthy_donor-Treg\|World / disease group, cell group and cell class (v2)	SPTAN1 SYNE2 ANKDD1B ATP8B2	7.27e-05	174	57	4	dc3b06420b0ad9c7060571e7bf5714e028d598bf
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GVINP1 GBP5 SYNE2 SMAP2	7.44e-05	175	57	4	8269721389a3ce98681460e6393f2cff816eaa25
ToppCell	facs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF20A ANGPT2 ANKDD1B FAM186B	7.77e-05	177	57	4	e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCell	facs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF20A ANGPT2 ANKDD1B FAM186B	7.77e-05	177	57	4	8a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRHDE RAB3IP SYNE2 PLEKHA7	8.84e-05	183	57	4	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GBP5 SPTAN1 SYNE2 ATP8B2	9.03e-05	184	57	4	08bff25390e3484b75c860738396a405141b69fd
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	GBP5 SPTAN1 SYNE2 ATP8B2	9.81e-05	188	57	4	72be6fe654f3a5f654d3b9680145bce7ae9b721d
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GBP5 SPTAN1 SYNE2 ATP8B2	9.81e-05	188	57	4	9db3d3010cb8a1f3ee1cdccaf3cbaac3cf983fc5
ToppCell	COVID-19_Mild-Lymphoid_T/NK-Treg\|COVID-19_Mild / Disease group, lineage and cell class	GBP5 SPTAN1 SYNE2 ATP8B2	9.81e-05	188	57	4	42553fdc127e5f613ffd5067620a768a40f1a8a1
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-regulatory_T_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GBP5 SPTAN1 SYNE2 ATP8B2	1.00e-04	189	57	4	9f6f6fe6e47f5c5fd48aab47a775f7bdd16de19c
ToppCell	severe-Lymphocytic-CD4_T_cells_3\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	GBP5 SPTAN1 SYNE2 ATP8B2	1.04e-04	191	57	4	afff6bfae9a2f1e17d2731315e7fe63c4601679f
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GBP5 SPTAN1 SYNE2 ATP8B2	1.06e-04	192	57	4	7a90ec9fc8f29216c4828e0cf5d040906456e53b
ToppCell	COVID-19_Severe-Lymphoid_T/NK-Treg\|COVID-19_Severe / Disease group, lineage and cell class	GBP5 SPTAN1 SYNE2 ATP8B2	1.06e-04	192	57	4	3fb4c148dadcf5e79094e55c6bb53ec7bf9d44c8
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GBP5 SPTAN1 SYNE2 ATP8B2	1.06e-04	192	57	4	d883b91bbab71673de4858346d3ab33e5fbbf842
ToppCell	COVID-19_Moderate-CD4+_Tcm\|World / disease group, cell group and cell class	SPTAN1 SYNE2 ATP8B2 GCSAM	1.06e-04	192	57	4	5f94310f1470487816fce697ffcdc2627fc66878
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SPTAN1 SYNE2 ATP8B2 GCSAM	1.06e-04	192	57	4	7ab626a516b07d899175ff12f1c8257688324e4b
ToppCell	Control-Lymphoid_T/NK-Treg\|Control / Disease group, lineage and cell class	GBP5 SPTAN1 SYNE2 ATP8B2	1.09e-04	193	57	4	715f2bbee12a7952cba85d9cd8820411983ce790
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GBP5 SPTAN1 SYNE2 ATP8B2	1.11e-04	194	57	4	fd3d5ac94de3db7136684c86f8589631ad87e6d8
ToppCell	IPF-Stromal-Pericyte\|Stromal / Disease state, Lineage and Cell class	ANGPT2 SYNE2 MOB3B DENND3	1.11e-04	194	57	4	3892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE RAB3IP EVC PLEKHA7	1.11e-04	194	57	4	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GVINP1 GBP5 SYNE2 GCSAM	1.11e-04	194	57	4	c49f3341a19128855f084bcf18ef3da4bab79099
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	GBP5 SPTAN1 SYNE2 ATP8B2	1.11e-04	194	57	4	2faf49d85d09932c9c20d9f675c8093ad802fae5
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GVINP1 GBP5 SYNE2 ATP8B2	1.13e-04	195	57	4	662b50a2aa97373bf343b88caace9717049c722a
ToppCell	Sepsis-URO-Lymphocyte-T/NK-Treg\|URO / Disease, condition lineage and cell class	SYNE2 PLEKHA7 TRAV25 GCSAM	1.15e-04	196	57	4	8812d7365fb2b33feff93782d60776e932499a43
ToppCell	mild-Treg\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GBP5 SPTAN1 SYNE2 ATP8B2	1.17e-04	197	57	4	39800e6e83f2d333b753d121c7aeb2912b91faa2
ToppCell	healthy_donor-Lymphocytic-T_cell-CD4+_Memory_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SPTAN1 SYNE2 ATP8B2 GCSAM	1.17e-04	197	57	4	c842d169dfce9af3ed7c01dc7e940c0bdd21388c
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pre_B_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MIS18BP1 RBBP4 SYNE2 GCSAM	1.17e-04	197	57	4	106b0f9a0425facc634feb7498c9ba2c55edfbf8
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / Treatment groups by lineage, cell group, cell type	KIF20A FICD MIS18BP1 EVC	1.17e-04	197	57	4	038fd92750257d43d5e980fd06d77742b543f11a
ToppCell	COVID_vent-Lymphocytic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	GBP5 SPTAN1 SYNE2 ATP8B2	1.20e-04	198	57	4	ee80f647317377081b4bd194ee2801f556b3a53b
ToppCell	Control-Control-Lymphocyte-T/NK-Treg\|Control / Disease, condition lineage and cell class	GBP5 SPTAN1 SYNE2 ATP8B2	1.22e-04	199	57	4	6b7eb14bf03aa05f2d4ac4f5dd1ccf41a7e47bd1
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B-B_lineage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MIS18BP1 RBBP4 SYNE2 GCSAM	1.22e-04	199	57	4	fe3b7d540a644dfc6beea171c809b4d1ba4e188f
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MIS18BP1 RBBP4 SYNE2 GCSAM	1.22e-04	199	57	4	cdee798e3586e4e7a15de598239090a85752ea1e
ToppCell	healthy_donor-Lymphocytic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	GBP5 SPTAN1 SYNE2 ATP8B2	1.22e-04	199	57	4	2841e16d54acd344ba454f024e285c28abc37319
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-Treg\|COVID-19_Severe / Disease, condition lineage and cell class	GBP5 SPTAN1 SYNE2 ATP8B2	1.24e-04	200	57	4	2b363f2a1d08019b6ff0b10419870049063cc1cf
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-Treg\|COVID-19_Mild / Disease, condition lineage and cell class	GBP5 SPTAN1 SYNE2 ATP8B2	1.24e-04	200	57	4	c6ae15f7deba26008af5b647855675003bb2ebcd
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(Neuron.Gad1Gad2.Pvalb-Unc5b)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KIF20A ANKDD1B CFAP65	1.42e-04	79	57	3	cc17a013a4a57a99c404b10449ef61ce559631d1
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(Neuron.Gad1Gad2.Pvalb-Unc5b)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KIF20A ANKDD1B CFAP65	1.42e-04	79	57	3	19fb2bc964589ea40e7b9f0809c641331c93dacd
Disease	Sphingomyelin (d18:2/23:0, d18:1/23:1, d17:1/24:1) measurement	SYNE2 FADS2	2.12e-05	4	56	2	EFO_0022116
Disease	hemoglobin A1 measurement	CUL3 THBS3 SYNE2 FADS2 ZYG11B UBE3C FLACC1	5.57e-05	520	56	7	EFO_0007629
Disease	temporomandibular joint disorder	RXFP2 PPP1R9B	1.58e-04	10	56	2	EFO_0005279
Disease	level of Sphingomyelin (d34:0) in blood serum	SYNE2 FADS2	1.92e-04	11	56	2	OBA_2045176
Disease	level of Sphingomyelin (d40:2) in blood serum	SYNE2 FADS2	8.72e-04	23	56	2	OBA_2045181
Disease	triacylglycerol 56:4 measurement	IPO8 FADS2	9.51e-04	24	56	2	EFO_0010431
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	SYNE2 ANKDD1B FADS2	1.83e-03	127	56	3	EFO_0008595, EFO_0020947
Disease	phosphatidylcholine 32:1 measurement	GVINP1 FADS2	2.38e-03	38	56	2	EFO_0010373
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	SYNE2 ANKDD1B FADS2	2.61e-03	144	56	3	EFO_0004611, EFO_0020943
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	SYNE2 ANKDD1B FADS2	2.93e-03	150	56	3	EFO_0004611, EFO_0020947
Disease	candidiasis (implicated_via_orthology)	SMAP1 SMAP2	3.18e-03	44	56	2	DOID:1508 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
YVNIQEVMDQWTLQM	TRHDE	581	Q9UKU6
LMENLQRQLNLMKWT	GVINP1	151	Q7Z2Y8
QVLENIMENNTQWLM	ANGPT2	81	O15123
RQQNTQEMPWNVRMQ	GCSAM	11	Q8N6F7
LKMMVGNNLTDWQLQ	PPP3R2	116	Q96LZ3
LQMARQQGKQMEAVW	FAM186B	841	Q8IYM0
MAQMNDVILSPNCWQ	ADCY10	181	Q96PN6
AKVNCMVMADQNQVW	DENND3	946	A2RUS2
VLINGILQQEQWMNV	ATP8B2	136	P98198
KQQDVDQMFWEVMQL	RAB3IP	446	Q96QF0
WPNNQFDTEMLQAMI	PCDHGA11	841	Q9Y5H2
IQVMDNIWLQEGLDM	PIK3C2G	936	O75747
WPNNQFDTEMLQAMI	PCDHGB6	836	Q9Y5F9
QYMNLLMDWIEVQIN	MOB3B	116	Q86TA1
WVTQMNHIVMEIDQE	FADS2	336	O95864
VDAMQNELQMWHSEN	TRAF3IP1	611	Q8TDR0
WNTENVNMLMNQLNP	FAR1	401	Q8WVX9
EEWLQETQQLLQMQQ	KMT2C	3181	Q8NEZ4
QVVQLQEWMIKSINN	MIS18BP1	381	Q6P0N0
WHDVLQQLLLMQVMQ	FLACC1	326	Q96Q35
MQWQWQQQLNVMVKE	CFAP65	1826	Q6ZU64
WFNMQMEELNQQVAT	KRT32	286	Q14532
MQEFVQWLNSEEAMN	FICD	331	Q9BVA6
GMNMEEEEELQQNLW	EIF2B5	501	Q13144
QETQLIQMVVWMLQR	NPRL3	386	Q12980
WLAEQQKMQEQQMQE	GBP5	536	Q96PP8
ILAWQQQLQDLQMTK	FBXO25	206	Q8TCJ0
ETAAGNIINMLWQLM	MON2	101	Q7Z3U7
NIINMLWQLMENSLE	MON2	106	Q7Z3U7
VENLNEMQCMWFQTE	NAA15	476	Q9BXJ9
DNIMQVWQMAENIYN	RBBP4	396	Q09028
NIMQIWQMAENIYND	RBBP7	396	Q16576
QNLMWQKDRIRQMQE	KLHL11	676	Q9NVR0
NQAWNDHQTAMVMIR	CUL3	106	Q13618
QDMESWLTNREQMQN	DENND5B	526	Q6ZUT9
AKMPQMIVNWQQQQR	GADD45GIP1	126	Q8TAE8
LNQEIWMMKNQRVQL	KIF4B	636	Q2VIQ3
IDNMEAFWKQMANIQ	EVC	311	P57679
LPLQLVNNQTMTTWM	IPO8	216	O15397
QAQEWMDNLMIPFQQ	SYNE2	3751	Q8WXH0
TQEDMNAWVRAMNQA	PLEKHA7	266	Q6IQ23
QMCAQMPQLNWVDLE	RXFP2	251	Q8WXD0
CQEMFNLLQMWLVSQ	MROH2B	886	Q7Z745
IMVMENVNKPQLWNI	GTF3C3	691	Q9Y5Q9
VQVLLAQWQDINEMN	ANKDD1B	251	A6NHY2
LVMQWLCNHEDQNMQ	ZYG11B	451	Q9C0D3
NMSWLHVMILLCNQQ	UNC80	1456	Q8N2C7
DQWTQEQIQCMQEMG	SMAP2	71	Q8WU79
QLQWNLTQMTQQMAG	SMAP2	381	Q8WU79
MVEQMQQREQWCSEH	KIF20A	596	O95235
AQQWDQLDQLGMRMQ	SPTAN1	2291	Q13813
DQWTAEQIQCMQDMG	SMAP1	76	Q8IYB5
WVVLNQGMEIVQTMN	THBS3	746	P49746
SMLVLWMQLSQVNGQ	TRAV25	6	A0A0B4J276
WMQLSQVNGQQVMQI	TRAV25	11	A0A0B4J276
LQQDANECWIQMMRV	USP14	196	P54578
VLENQMFIIWNKMNH	TEX46	71	H3BTG2
EMQQCIQMEQKRWIQ	UBE3C	586	Q15386
NLPWMNEETQNMAQD	KEL	456	P23276
QQTLEQERWQREMME	PPP1R9B	596	Q96SB3