Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	inositol 1,4,5-trisphosphate-gated calcium channel activity	ITPR2 ITPR3	7.57e-05	3	101	2	GO:0005220
GeneOntologyMolecularFunction	pentosyltransferase activity	TIPARP PARP4 LACC1 QTRT1	1.85e-04	56	101	4	GO:0016763
GeneOntologyCellularComponent	sarcoplasmic reticulum	ANK1 ITPR2 ITPR3 AGL	6.70e-04	88	94	4	GO:0016529
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex, class I	PIK3R3 PIK3R1	7.06e-04	9	94	2	GO:0097651
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex, class IA	PIK3R3 PIK3R1	7.06e-04	9	94	2	GO:0005943
GeneOntologyCellularComponent	platelet dense tubular network membrane	ITPR2 ITPR3	7.06e-04	9	94	2	GO:0031095
GeneOntologyCellularComponent	bBAF complex	SMARCA2 SMARCA4	8.79e-04	10	94	2	GO:0140092
GeneOntologyCellularComponent	SWI/SNF superfamily-type complex	MYBBP1A CHD4 SMARCA2 SMARCA4	9.29e-04	96	94	4	GO:0070603
GeneOntologyCellularComponent	platelet dense tubular network	ITPR2 ITPR3	1.07e-03	11	94	2	GO:0031094
MousePheno	increased circulating bilirubin level	ANK1 GALNT3 TMEM127 KBTBD7 AGL SMARCA2 LRP6 ABCC2	9.99e-06	205	72	8	MP:0005344
MousePheno	enlarged stomach	ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	2.36e-05	33	72	4	MP:0003883
MousePheno	abnormal circulating bilirubin level	ANK1 GALNT3 TMEM127 KBTBD7 AGL SMARCA2 LRP6 ABCC2	4.29e-05	251	72	8	MP:0001569
MousePheno	enlarged liver	GAPVD1 ANK1 LGALS3 TIPARP AGL LRP6 KMT2A ABCC2	4.54e-05	253	72	8	MP:0000599
MousePheno	abnormal frontal bone morphology	HDAC8 TIPARP GLI2 ARID5B LRP6	4.66e-05	77	72	5	MP:0000107
MousePheno	abnormal sternum morphology	ANKRD20A3P ANKRD20A8P TIPARP ANKRD20A4P GLI2 ARID5B KMT2A ANKRD20A1	4.80e-05	255	72	8	MP:0000157
MousePheno	abnormal pectoral girdle bone morphology	ANKRD20A3P ANKRD20A8P TIPARP ANKRD20A4P GLI2 ARID5B KMT2A ANKRD20A1	1.52e-04	301	72	8	MP:0004508
Domain	SnAC	SMARCA2 SMARCA4	2.67e-05	2	97	2	SM01314
Domain	Gln-Leu-Gln_QLQ	SMARCA2 SMARCA4	2.67e-05	2	97	2	IPR014978
Domain	SnAC	SMARCA2 SMARCA4	2.67e-05	2	97	2	IPR029295
Domain	SnAC	SMARCA2 SMARCA4	2.67e-05	2	97	2	PF14619
Domain	QLQ	SMARCA2 SMARCA4	2.67e-05	2	97	2	SM00951
Domain	QLQ	SMARCA2 SMARCA4	2.67e-05	2	97	2	PS51666
Domain	QLQ	SMARCA2 SMARCA4	2.67e-05	2	97	2	PF08880
Domain	InsP3_rcpt-bd	ITPR2 ITPR3	7.98e-05	3	97	2	IPR000493
Domain	PI3K_P85_iSH2	PIK3R3 PIK3R1	7.98e-05	3	97	2	IPR032498
Domain	PI3K_P85_iSH2	PIK3R3 PIK3R1	7.98e-05	3	97	2	PF16454
Domain	HSA	SMARCA2 SMARCA4	1.59e-04	4	97	2	SM00573
Domain	HSA	SMARCA2 SMARCA4	1.59e-04	4	97	2	PS51204
Domain	HSA_dom	SMARCA2 SMARCA4	1.59e-04	4	97	2	IPR014012
Domain	HSA	SMARCA2 SMARCA4	1.59e-04	4	97	2	PF07529
Domain	PI3kinase_P85	PIK3R3 PIK3R1	2.64e-04	5	97	2	IPR001720
Domain	BRK	SMARCA2 SMARCA4	3.95e-04	6	97	2	SM00592
Domain	RIH_assoc	ITPR2 ITPR3	3.95e-04	6	97	2	PF08454
Domain	RIH_assoc-dom	ITPR2 ITPR3	3.95e-04	6	97	2	IPR013662
Domain	RIH_dom	ITPR2 ITPR3	3.95e-04	6	97	2	IPR000699
Domain	Ins145_P3_rcpt	ITPR2 ITPR3	3.95e-04	6	97	2	IPR014821
Domain	Ryanodine_recept-rel	ITPR2 ITPR3	3.95e-04	6	97	2	IPR015925
Domain	-	ITPR2 ITPR3	3.95e-04	6	97	2	1.25.10.30
Domain	BRK_domain	SMARCA2 SMARCA4	3.95e-04	6	97	2	IPR006576
Domain	RYDR_ITPR	ITPR2 ITPR3	3.95e-04	6	97	2	PF01365
Domain	BRK	SMARCA2 SMARCA4	3.95e-04	6	97	2	PF07533
Domain	Ins145_P3_rec	ITPR2 ITPR3	3.95e-04	6	97	2	PF08709
Domain	SNF2_N	CHD4 SMARCA2 SMARCA4	6.04e-04	32	97	3	IPR000330
Domain	SNF2_N	CHD4 SMARCA2 SMARCA4	6.04e-04	32	97	3	PF00176
Domain	Ank_2	ANK1 ANKRD20A2P ANKRD20A3P ANKRD20A4P NFKBIE ANKRD20A1	8.98e-04	215	97	6	PF12796
Domain	MIR	ITPR2 ITPR3	1.17e-03	10	97	2	PS50919
Domain	MIR	ITPR2 ITPR3	1.17e-03	10	97	2	PF02815
Domain	MIR	ITPR2 ITPR3	1.17e-03	10	97	2	SM00472
Domain	MIR_motif	ITPR2 ITPR3	1.17e-03	10	97	2	IPR016093
Domain	Ank	ANK1 ANKRD20A2P ANKRD20A3P ANKRD20A4P NFKBIE ANKRD20A1	1.22e-03	228	97	6	PF00023
Domain	BROMODOMAIN_2	SMARCA2 SMARCA4 KMT2A	1.25e-03	41	97	3	PS50014
Domain	BROMO	SMARCA2 SMARCA4 KMT2A	1.35e-03	42	97	3	SM00297
Domain	Bromodomain	SMARCA2 SMARCA4 KMT2A	1.35e-03	42	97	3	IPR001487
Domain	-	SMARCA2 SMARCA4 KMT2A	1.35e-03	42	97	3	1.20.920.10
Domain	-	ANK1 ANKRD20A2P ANKRD20A3P ANKRD20A4P NFKBIE ANKRD20A1	1.86e-03	248	97	6	1.25.40.20
Domain	ANK	ANK1 ANKRD20A2P ANKRD20A3P ANKRD20A4P NFKBIE ANKRD20A1	1.98e-03	251	97	6	SM00248
Domain	ANK_REPEAT	ANK1 ANKRD20A2P ANKRD20A3P ANKRD20A4P NFKBIE ANKRD20A1	2.06e-03	253	97	6	PS50088
Domain	Ankyrin_rpt-contain_dom	ANK1 ANKRD20A2P ANKRD20A3P ANKRD20A4P NFKBIE ANKRD20A1	2.10e-03	254	97	6	IPR020683
Domain	ANK_REP_REGION	ANK1 ANKRD20A2P ANKRD20A3P ANKRD20A4P NFKBIE ANKRD20A1	2.10e-03	254	97	6	PS50297
Domain	Helicase_C	DHX57 CHD4 SMARCA2 SMARCA4	2.34e-03	107	97	4	PF00271
Domain	HELICc	DHX57 CHD4 SMARCA2 SMARCA4	2.34e-03	107	97	4	SM00490
Domain	Helicase_C	DHX57 CHD4 SMARCA2 SMARCA4	2.43e-03	108	97	4	IPR001650
Domain	Ankyrin_rpt	ANK1 ANKRD20A2P ANKRD20A3P ANKRD20A4P NFKBIE ANKRD20A1	2.45e-03	262	97	6	IPR002110
Domain	HELICASE_CTER	DHX57 CHD4 SMARCA2 SMARCA4	2.51e-03	109	97	4	PS51194
Domain	HELICASE_ATP_BIND_1	DHX57 CHD4 SMARCA2 SMARCA4	2.51e-03	109	97	4	PS51192
Domain	DEXDc	DHX57 CHD4 SMARCA2 SMARCA4	2.51e-03	109	97	4	SM00487
Domain	Helicase_ATP-bd	DHX57 CHD4 SMARCA2 SMARCA4	2.59e-03	110	97	4	IPR014001
Domain	Poly(ADP-ribose)pol_cat_dom	TIPARP PARP4	3.45e-03	17	97	2	IPR012317
Domain	PARP_CATALYTIC	TIPARP PARP4	3.45e-03	17	97	2	PS51059
Domain	PARP	TIPARP PARP4	3.45e-03	17	97	2	PF00644
Domain	-	TIPARP PARP4	3.45e-03	17	97	2	3.90.228.10
Pathway	REACTOME_INTERLEUKIN_7_SIGNALING	PIK3R3 PIK3R1 SMARCA4	4.48e-05	15	67	3	MM14536
Pathway	REACTOME_RAC2_GTPASE_CYCLE	DOCK3 PIK3R3 PIK3R1 SLITRK5 GARRE1	6.02e-05	88	67	5	M41810
Pathway	WP_RETT_SYNDROME	HDAC8 CHD4 SMARCA2 SMARCA4	7.75e-05	48	67	4	M39759
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	4.84e-09	8	102	4	12634303
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CFAP47 GAPVD1 ANK1 CCDC73 TTC21A MAGI3 SYNC ANKRD20A3P ITPR2 PARP4 AGL ARID5B UTP20	2.55e-07	736	102	13	29676528
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TPR MYBBP1A GAPVD1 DHX57 CHD4 ITPR3 NOP14 SMARCA2 SMARCA4 KMT2A UTP20 NUP160	5.04e-07	653	102	12	22586326
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	CHD4 SMARCA2 SMARCA4 KMT2A ZFHX3 ZMYM4	6.23e-07	103	102	6	32744500
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	TPR GAPVD1 CHD4 KBTBD7 TBC1D32 NOP14 AGL SMARCA4 UTP20 NUP160 ZMYM4 ANKRD20A1 DCP1A	1.40e-06	857	102	13	25609649
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MYBBP1A DHX57 ITPR3 PARP4 SMARCA2 UTP20 TTC17	2.33e-06	202	102	7	33005030
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	TPR FKBP15 MYBBP1A CHD4 AGL LRP6 KMT2A	2.33e-06	202	102	7	24639526
Pubmed	Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes.	CHD4 SMARCA2 SMARCA4	3.97e-06	11	102	3	10204490
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	TPR MYBBP1A CHD4 ARID5B SMARCA2 ZFHX3 ZMYM4	4.09e-06	220	102	7	35785414
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	MYBBP1A GAPVD1 LRCH2 CHD4 ITPR2 ITPR3 SMARCA2 SMARCA4 NUP160	6.20e-06	440	102	9	34244565
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	CHD4 ZNF585B ZNF23 GLI2 NFKBIE SMARCA2 SMARCA4 KMT2A ZFHX3 DCP1A ZNF292	7.76e-06	709	102	11	22988430
Pubmed	The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.	SMARCA2 SMARCA4	8.52e-06	2	102	2	8670841
Pubmed	Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin.	ITPR2 ITPR3	8.52e-06	2	102	2	9065779
Pubmed	Expression of IP3 receptor isoforms at the nodes of Ranvier in rat sciatic nerve.	ITPR2 ITPR3	8.52e-06	2	102	2	17496801
Pubmed	Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.	SMARCA2 SMARCA4	8.52e-06	2	102	2	23163725
Pubmed	The phosphatidylinositol 3-kinase-mediated production of interferon-beta is critical for the lipopolysaccharide inhibition of osteoclastogenesis.	IFNB1 PIK3R1	8.52e-06	2	102	2	18675826
Pubmed	Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.	SMARCA2 SMARCA4	8.52e-06	2	102	2	23076393
Pubmed	Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein.	SMARCA2 SMARCA4	8.52e-06	2	102	2	9603422
Pubmed	The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.	SMARCA2 SMARCA4	8.52e-06	2	102	2	15576411
Pubmed	Mice lacking inositol 1,4,5-trisphosphate receptors exhibit dry eye.	ITPR2 ITPR3	8.52e-06	2	102	2	24901844
Pubmed	SWI/SNF gene variants and glioma risk and outcome.	SMARCA2 SMARCA4	8.52e-06	2	102	2	23276717
Pubmed	Differential Expression of SWI/SNF Chromatin Remodeler Subunits Brahma and Brahma-Related Gene During Drug-Induced Liver Injury and Regeneration in Mouse Model.	SMARCA2 SMARCA4	8.52e-06	2	102	2	27097303
Pubmed	Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.	SMARCA2 SMARCA4	8.52e-06	2	102	2	15240517
Pubmed	Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.	SMARCA2 SMARCA4	8.52e-06	2	102	2	26564006
Pubmed	Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization.	ITPR2 ITPR3	8.52e-06	2	102	2	33854148
Pubmed	SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.	SMARCA2 SMARCA4	8.52e-06	2	102	2	33027072
Pubmed	SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.	SMARCA2 SMARCA4	8.52e-06	2	102	2	28038711
Pubmed	A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.	SMARCA2 SMARCA4	8.52e-06	2	102	2	23872584
Pubmed	Proinflammatory stimuli engage Brahma related gene 1 and Brahma in endothelial injury.	SMARCA2 SMARCA4	8.52e-06	2	102	2	23963727
Pubmed	SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level.	SMARCA2 SMARCA4	8.52e-06	2	102	2	12493776
Pubmed	Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4.	SMARCA2 SMARCA4	8.52e-06	2	102	2	31375262
Pubmed	Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.	SMARCA2 SMARCA4	8.52e-06	2	102	2	23088494
Pubmed	The involvement of ankyrin in the regulation of inositol 1,4,5-trisphosphate receptor-mediated internal Ca2+ release from Ca2+ storage vesicles in mouse T-lymphoma cells.	ANK1 ITPR3	8.52e-06	2	102	2	8385102
Pubmed	Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers.	SMARCA2 SMARCA4	8.52e-06	2	102	2	17075831
Pubmed	Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors.	ITPR2 ITPR3	8.52e-06	2	102	2	19528657
Pubmed	SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.	SMARCA2 SMARCA4	8.52e-06	2	102	2	20333683
Pubmed	SWI/SNF Complex-deficient Undifferentiated Carcinoma of the Gastrointestinal Tract: Clinicopathologic Study of 30 Cases With an Emphasis on Variable Morphology, Immune Features, and the Prognostic Significance of Different SMARCA4 and SMARCA2 Subunit Deficiencies.	SMARCA2 SMARCA4	8.52e-06	2	102	2	34812766
Pubmed	Determination of relative amounts of inositol trisphosphate receptor mRNA isoforms by ratio polymerase chain reaction.	ITPR2 ITPR3	8.52e-06	2	102	2	8063813
Pubmed	Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma.	SMARCA2 SMARCA4	8.52e-06	2	102	2	32855269
Pubmed	Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.	ITPR2 ITPR3	8.52e-06	2	102	2	8081734
Pubmed	Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy.	SMARCA2 SMARCA4	8.52e-06	2	102	2	30478150
Pubmed	Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.	SMARCA2 SMARCA4	8.52e-06	2	102	2	22721696
Pubmed	Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter.	SMARCA2 SMARCA4	8.52e-06	2	102	2	18508913
Pubmed	Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.	SMARCA2 SMARCA4	8.52e-06	2	102	2	11719516
Pubmed	IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism.	ITPR2 ITPR3	8.52e-06	2	102	2	16195467
Pubmed	The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.	SMARCA2 SMARCA4	8.52e-06	2	102	2	25808524
Pubmed	Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation.	SMARCA2 SMARCA4	8.52e-06	2	102	2	19144648
Pubmed	DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes.	SMARCA2 SMARCA4	8.52e-06	2	102	2	28706277
Pubmed	Epigenome-wide association of myocardial infarction with DNA methylation sites at loci related to cardiovascular disease.	SMARCA4 ZFHX3	8.52e-06	2	102	2	28515798
Pubmed	[Expression of BRG1 and BRM proteins in prostatic cancer].	SMARCA2 SMARCA4	8.52e-06	2	102	2	21092585
Pubmed	High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer.	SMARCA2 SMARCA4	8.52e-06	2	102	2	29391527
Pubmed	Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.	ITPR2 ITPR3	8.52e-06	2	102	2	15632133
Pubmed	Expression of SMARCA2 and SMARCA4 in gastric adenocarcinoma and construction of a nomogram prognostic model.	SMARCA2 SMARCA4	8.52e-06	2	102	2	37634210
Pubmed	SWI/SNF Complex-deficient Undifferentiated/Rhabdoid Carcinomas of the Gastrointestinal Tract: A Series of 13 Cases Highlighting Mutually Exclusive Loss of SMARCA4 and SMARCA2 and Frequent Co-inactivation of SMARCB1 and SMARCA2.	SMARCA2 SMARCA4	8.52e-06	2	102	2	26551623
Pubmed	Inositol (1,4,5)-trisphosphate receptor links to filamentous actin are important for generating local Ca2+ signals in pancreatic acinar cells.	ITPR2 ITPR3	8.52e-06	2	102	2	15713744
Pubmed	SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity.	SMARCA2 SMARCA4	8.52e-06	2	102	2	19458193
Pubmed	Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.	SMARCA2 SMARCA4	8.52e-06	2	102	2	8208605
Pubmed	The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation.	SMARCA2 SMARCA4	8.52e-06	2	102	2	34289068
Pubmed	SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria.	SMARCA2 SMARCA4	8.52e-06	2	102	2	34518526
Pubmed	SMARCA family of genes.	SMARCA2 SMARCA4	8.52e-06	2	102	2	32312722
Pubmed	Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.	SMARCA2 SMARCA4	8.52e-06	2	102	2	26356327
Pubmed	Loss of BRG1/BRM in human lung cancer cell lines and primary lung cancers: correlation with poor prognosis.	SMARCA2 SMARCA4	8.52e-06	2	102	2	12566296
Pubmed	A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.	SMARCA2 SMARCA4	8.52e-06	2	102	2	11163203
Pubmed	Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.	SMARCA2 SMARCA4	8.52e-06	2	102	2	12620226
Pubmed	SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines.	SMARCA2 SMARCA4	8.52e-06	2	102	2	31406271
Pubmed	BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.	SMARCA2 SMARCA4	8.52e-06	2	102	2	27039070
Pubmed	Partial Inactivation of the Chromatin Remodelers SMARCA2 and SMARCA4 in Virus-Infected Cells by Caspase-Mediated Cleavage.	SMARCA2 SMARCA4	8.52e-06	2	102	2	29848589
Pubmed	Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits.	SMARCA2 SMARCA4	8.52e-06	2	102	2	29273066
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK3 MAGI3 NEK1 PARP4 USF3 SUN2 SLITRK5 NUP160 DOP1A	1.53e-05	493	102	9	15368895
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	GAPVD1 ANK1 DHX57 USP9Y NEB NSUN7 ZNF540 KMT2A ZNF292	1.63e-05	497	102	9	36774506
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TPR MYBBP1A GAPVD1 ERCC5 CHD4 SMARCA2 SMARCA4 KMT2A UTP20 ZMYM4 DCP1A	1.75e-05	774	102	11	15302935
Pubmed	A protein interaction landscape of breast cancer.	TPR MYBBP1A GAPVD1 PIK3R3 NUCB2 ITPR3 PIK3R1 SMARCA2 SMARCA4 GOLIM4	1.79e-05	634	102	10	34591612
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	FKBP15 DHX57 ARFIP1 SPG21 ITPR2 ITPR3 PIK3R1 SUN2 RMC1	1.82e-05	504	102	9	34432599
Pubmed	TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.	CHD4 SMARCA2 SMARCA4	1.94e-05	18	102	3	28068325
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	STARD13 MYBBP1A ERCC5 NUCB2 MAGI3 DHX57 CHD4 NEB NOP14 KMT2A ABCC2 PCID2 CFAP46 DOP1A ZNF292	2.01e-05	1442	102	15	35575683
Pubmed	Rescue of calcineurin Aα(-/-) mice reveals a novel role for the α isoform in the salivary gland.	ITPR2 ITPR3	2.55e-05	3	102	2	21435446
Pubmed	Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.	ITPR2 ITPR3	2.55e-05	3	102	2	10874040
Pubmed	Selective Killing of SMARCA2- and SMARCA4-deficient Small Cell Carcinoma of the Ovary, Hypercalcemic Type Cells by Inhibition of EZH2: In Vitro and In Vivo Preclinical Models.	SMARCA2 SMARCA4	2.55e-05	3	102	2	28292935
Pubmed	Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.	ITPR2 ITPR3	2.55e-05	3	102	2	9808793
Pubmed	The N-terminal 24 amino acids of the p55 gamma regulatory subunit of phosphoinositide 3-kinase binds Rb and induces cell cycle arrest.	PIK3R3 PIK3R1	2.55e-05	3	102	2	12588990
Pubmed	Clinicopathological and prognostic significance of SWI/SNF complex subunits in undifferentiated gastric carcinoma.	SMARCA2 SMARCA4	2.55e-05	3	102	2	36464671
Pubmed	DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1.	SMARCA2 SMARCA4	2.55e-05	3	102	2	30287812
Pubmed	Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.	ITPR2 ITPR3	2.55e-05	3	102	2	20395455
Pubmed	Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.	ITPR2 ITPR3	2.55e-05	3	102	2	17437169
Pubmed	Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.	ITPR2 ITPR3	2.55e-05	3	102	2	18194433
Pubmed	Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.	ITPR2 ITPR3	2.55e-05	3	102	2	18547250
Pubmed	Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.	ITPR2 ITPR3	2.55e-05	3	102	2	36350267
Pubmed	IP3 receptors regulate vascular smooth muscle contractility and hypertension.	ITPR2 ITPR3	2.55e-05	3	102	2	27777977
Pubmed	The versatility and universality of calcium signalling.	ITPR2 ITPR3	2.55e-05	3	102	2	11413485
Pubmed	Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.	ITPR2 ITPR3	2.55e-05	3	102	2	26009177
Pubmed	Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.	ITPR2 ITPR3	2.55e-05	3	102	2	17581770
Pubmed	Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.	ITPR2 ITPR3	2.55e-05	3	102	2	18241669
Pubmed	Receptor-activated single channels in intact human platelets.	ITPR2 ITPR3	2.55e-05	3	102	2	1693919
Pubmed	Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.	ITPR2 ITPR3	2.55e-05	3	102	2	19068129
Pubmed	Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.	ITPR2 ITPR3	2.55e-05	3	102	2	23955339
Pubmed	Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.	ITPR2 ITPR3	2.55e-05	3	102	2	31979185
Pubmed	The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes.	SMARCA2 SMARCA4	2.55e-05	3	102	2	17938176
Pubmed	Functional redundancy of SWI/SNF catalytic subunits in maintaining vascular endothelial cells in the adult heart.	SMARCA2 SMARCA4	2.55e-05	3	102	2	22740088
Pubmed	BRCA1 interacts with dominant negative SWI/SNF enzymes without affecting homologous recombination or radiation-induced gene activation of p21 or Mdm2.	SMARCA2 SMARCA4	2.55e-05	3	102	2	15034933
Pubmed	Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.	ITPR2 ITPR3	2.55e-05	3	102	2	24904548
Interaction	ANKRD20A4P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	2.21e-06	6	98	3	int:ANKRD20A4P
Interaction	ANKRD20A2P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	3.85e-06	7	98	3	int:ANKRD20A2P
Interaction	L3MBTL2 interactions	MYBBP1A GAS8 CHD4 KBTBD7 TIPARP ITPR2 ITPR3 SMARCA4	1.71e-05	231	98	8	int:L3MBTL2
Interaction	ANKRD20A1 interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	1.79e-05	11	98	3	int:ANKRD20A1
Interaction	MYB interactions	MYBBP1A SMARCA2 KMT2A ZFHX3 ZMYM4 ZNF292	4.72e-05	133	98	6	int:MYB
Interaction	MECOM interactions	TPR MYBBP1A PIK3R3 MAGI3 CHD4 NEB TIPARP SMARCA4 NUP160	6.25e-05	358	98	9	int:MECOM
Interaction	SIRT7 interactions	TPR MYBBP1A GAPVD1 DHX57 CHD4 KBTBD7 ITPR3 NOP14 SMARCA2 SMARCA4 KMT2A UTP20 NUP160	6.35e-05	744	98	13	int:SIRT7
Interaction	LRRC31 interactions	MYBBP1A DHX57 ITPR3 PARP4 SMARCA2 UTP20 TTC17	6.44e-05	205	98	7	int:LRRC31
Cytoband	4q12	DCUN1D4 RASL11B EXOC1	2.57e-04	55	102	3	4q12
Cytoband	19q13.12	ZNF850 ZNF585B ZNF540	5.68e-04	72	102	3	19q13.12
GeneFamily	Inositol 1,4,5-triphosphate receptors\|Protein phosphatase 1 regulatory subunits	ITPR2 ITPR3	3.69e-05	3	64	2	297
GeneFamily	Ankyrin repeat domain containing	ANK1 ANKRD20A2P ANKRD20A3P ANKRD20A4P NFKBIE ANKRD20A1	2.12e-04	242	64	6	403
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF717 ZNF236 ZNF850 ZNF585B ZNF23 GLI2 ZNF540 ZFHX3 ZNF292	9.10e-04	718	64	9	28
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	TIPARP PARP4	1.62e-03	17	64	2	684
GeneFamily	Polypeptide N-acetylgalactosaminyltransferases	GALNT15 GALNT3	2.25e-03	20	64	2	433
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_1000	DOCK3 ZNF717 CCDC73 PIK3R3 MAGI3 NEK1 LACC1 SMC1B DOP1A	1.93e-07	187	97	9	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k3_1000
ToppCell	AT2_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	CCDC73 ANKRD20A2P ANKRD20A3P USP9Y ANKRD20A4P CCDC40	5.81e-07	131	102	6	ff4e618bd944f852bbd34438f740187aca82460f
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF6 GALNT3 NUCB2 LGALS3 LACC1 SMC1B	2.32e-06	166	102	6	03a47b8687f54955e84df1edcb230db332c4ca8f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 PDE3A LRCH2 ANKRD20A4P ZFHX3 CDH13	3.14e-06	175	102	6	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 PDE3A LRCH2 ANKRD20A4P ZFHX3 CDH13	3.14e-06	175	102	6	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	STARD13 PIK3R3 KIAA1549 ANKRD20A2P ANKRD20A3P ANKRD20A4P	6.20e-06	197	102	6	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	CHD4 NEB LGALS3 ITPR2 ARID5B GOLIM4	6.76e-06	200	102	6	5ba4ed490c64b3bb738e7729669f893fa73aa56f
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 TTC21A TMEM232 CFAP46 CCDC40	4.37e-05	169	102	5	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CFAP47 TTC21A TMEM232 CFAP46 CCDC40	5.02e-05	174	102	5	f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CFAP47 TTC21A TMEM232 CFAP46 CCDC40	5.16e-05	175	102	5	c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCell	Control-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	6.55e-05	184	102	5	c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	VPS11 GALNT3 TMEM127 USF3 ZNF540	6.55e-05	184	102	5	e6bf826be31e1723e24c366fc5a1cee9b15589bc
ToppCell	COPD-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	6.55e-05	184	102	5	42d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDE3A PIK3R3 ZNF585B ITPR3 SMC1B	6.72e-05	185	102	5	87151ab95530e70d61328b336518df58db584acb
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 TTC21A TMEM232 CFAP46 CCDC40	6.72e-05	185	102	5	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	IPF-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	6.89e-05	186	102	5	962c2dada19185628ead77c32fcb07fa95114247
ToppCell	Control-Myeloid-cDC1\|Control / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	6.89e-05	186	102	5	b05c394aa3573ba855abc3066739ca193883b0c3
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|368C / Donor, Lineage, Cell class and subclass (all cells)	STARD13 PIK3R3 MAGI3 KBTBD7 PARP4	7.07e-05	187	102	5	b827d9da7032bf051756ddf88352af922eb0f87b
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	STARD13 PIK3R3 MAGI3 KBTBD7 PARP4	7.07e-05	187	102	5	61c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCell	IPF-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	7.25e-05	188	102	5	47bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCell	IPF-Myeloid-cDC1\|IPF / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	7.25e-05	188	102	5	2331a2bae1383820d598e93aa86c75b101069bac
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 PDE3A PIK3R1 GLI2 CDH13	7.62e-05	190	102	5	2e592323085ba9c019d678ac2a784462ab470ed9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 PDE3A PIK3R1 GLI2 CDH13	7.62e-05	190	102	5	445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A LRCH2 GLI2 ZFHX3 CDH13	7.81e-05	191	102	5	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	COPD-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	7.81e-05	191	102	5	3480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCell	COPD-Myeloid-cDC1\|COPD / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	8.00e-05	192	102	5	bd3d00b094d92463b06023361a71240851a542b8
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 SYNC ZNF23 ARID5B SLITRK5	8.20e-05	193	102	5	1aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCell	facs-Skin-Telogen-3m-Epithelial\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3R1 ARID5B SMARCA2 GOLIM4 CDH13	8.40e-05	194	102	5	4d7fc4d0a55abb3b645116d13a983bbedc55f70c
ToppCell	facs-Skin-Telogen-3m\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3R1 ARID5B SMARCA2 GOLIM4 CDH13	8.40e-05	194	102	5	ba10fc5929649bb994c3f1d2ce6ca3167fa9b11b
ToppCell	facs-Skin-Telogen\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3R1 ARID5B SMARCA2 GOLIM4 CDH13	8.40e-05	194	102	5	bafecab8d48fc94ffd93f0d054b5f32c04b6b3f6
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM\|Liver / Manually curated celltypes from each tissue	IDI1 PIK3R1 CRTAM SMARCA2 KMT2A	8.61e-05	195	102	5	972b09697b7b66fb8a27dfc0c0b05a844121f055
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo\|Liver / Manually curated celltypes from each tissue	IDI1 PIK3R1 CRTAM SMARCA2 KMT2A	8.61e-05	195	102	5	c29c4ae95a756e3ced0f0747bbfe343590e5b8ab
ToppCell	(2)_Fibroblasts-(23)_Fibro-4\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	GALNT15 NUCB2 KIAA1549 LGALS3 CDH13	9.03e-05	197	102	5	a183919023a4aca90a06be0e5e89c817b38c5574
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-Treg\|ICU-NoSEP / Disease, condition lineage and cell class	USP9Y ZNF850 ZNF540 ARID5B ABCC2	9.25e-05	198	102	5	1ed4dfe5565328cb0f7ef31e6b2f67dfbdf3e2ac
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	TPR PIK3R1 ARID5B SMARCA2 ZNF292	9.47e-05	199	102	5	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 TTC21A TMEM232 CFAP46 CCDC40	9.69e-05	200	102	5	31d75c26055177d656df1fbb10b764cebd61e122
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 TTC21A TMEM232 CFAP46 CCDC40	9.69e-05	200	102	5	e1dce91c6c531bb212002a14705e496d77ad3490
Computational	Genes upregulated in subsets of cells of a given type within various tumors	NOP14 GOLIM4 KMT2A ZMYM4	1.46e-04	50	58	4	GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Drug	tyrphostin AG-825; Down 200; 25.2uM; MCF7; HT_HG-U133A_EA	PIK3R3 TIPARP PIK3R1 ARID5B KMT2A DOP1A ZNF292	1.89e-05	185	101	7	1114_DN
Drug	adenophostin A	ITPR2 ITPR3	1.95e-05	2	101	2	ctd:C085029
Drug	indomethacin, USP; Up 200; 100uM; PC3; HG-U133A	ARFIP1 TMEM127 AGL LRP6 QTRT1 CWF19L1 DCP1A	2.40e-05	192	101	7	452_UP
Drug	Pronethalol hydrochloride [51-02-5]; Down 200; 15uM; MCF7; HT_HG-U133A	TPR FKBP15 NEK1 SMARCA2 LRP6 KMT2A UTP20	2.40e-05	192	101	7	4104_DN
Drug	2-propylpentanoic acid; Up 200; 200uM; HL60; HT_HG-U133A	GAS8 DHX57 ITPR2 SLITRK5 NIPAL2 ZFHX3 ABCC2	2.56e-05	194	101	7	6173_UP
Drug	Apomorphine hydrochloride hemihydrate [41372-20-7]; Down 200; 6.4uM; HL60; HG-U133A	IGSF6 ZNF236 TMEM127 NEK1 SMARCA4 ZMYM4 DOP1A	2.73e-05	196	101	7	2005_DN
Drug	Sulfameter [651-06-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A	STARD13 TPR ARFIP1 DCUN1D4 SUN2 GOLIM4 KMT2A	2.82e-05	197	101	7	6212_DN
Drug	DAPM	DOCK3 TPR IFNB1 SMARCA2 SMARCA4 NUP160	3.10e-05	135	101	6	CID000007577
Disease	lung non-small cell carcinoma (is_implicated_in)	ERCC5 SMARCA4 ZFHX3 ABCC2 CDH13	8.46e-05	139	94	5	DOID:3908 (is_implicated_in)
Disease	MENTAL RETARDATION, AUTOSOMAL DOMINANT 12	SMARCA2 SMARCA4	9.98e-05	5	94	2	C3281201
Disease	sleep duration	ANK1 METTL4 NEK1 KMT2A NUP160 ZMYM4 CDH13	1.62e-04	362	94	7	EFO_0005271
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	CETP LGALS3 SMARCA4	1.74e-04	34	94	3	EFO_0008317, EFO_0008596, EFO_0020944
Disease	Burkitt Lymphoma	PIK3R1 SMARCA4 KMT2A	2.07e-04	36	94	3	C0006413
Disease	Cornelia De Lange Syndrome	HDAC8 KMT2A	2.78e-04	8	94	2	C0270972
Disease	opportunistic bacterial infectious disease (implicated_via_orthology)	SMARCA2 SMARCA4	3.56e-04	9	94	2	DOID:0050340 (implicated_via_orthology)
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	CETP LGALS3 SMARCA4	4.30e-04	46	94	3	EFO_0008317, EFO_0008596, EFO_0020943
Disease	urinary 6‑hydroxymelatonin sulfate to creatinine ratio	GALNT15 ZFHX3	4.44e-04	10	94	2	EFO_0021488
Disease	endometrial carcinoma (is_implicated_in)	PIK3R1 CDH13	6.49e-04	12	94	2	DOID:2871 (is_implicated_in)
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	ITPR2 ITPR3	6.49e-04	12	94	2	DOID:1441 (implicated_via_orthology)
Disease	visual perception measurement	DOCK3 ITPR3 KMT2A PCID2 CFAP46	7.50e-04	223	94	5	EFO_0009700
Disease	Coffin-Siris syndrome	SMARCA2 SMARCA4	7.65e-04	13	94	2	C0265338
Disease	Vitiligo, response to rhododendrol	LGALS3 CDH13	7.65e-04	13	94	2	EFO_0004208, EFO_0010824
Disease	Prostatic Neoplasms	MYBBP1A GALNT3 NUCB2 PIK3R1 KMT2A ZFHX3 CDH13 ZNF292	7.95e-04	616	94	8	C0033578
Disease	Malignant neoplasm of prostate	MYBBP1A GALNT3 NUCB2 PIK3R1 KMT2A ZFHX3 CDH13 ZNF292	7.95e-04	616	94	8	C0376358
Disease	cognitive behavioural therapy	METTL4 NEB ZFHX3	8.51e-04	58	94	3	EFO_0007820
Disease	schizophrenia, intelligence, self reported educational attainment	LGALS3 NEK1 LACC1 SMARCA2 KMT2A CDH13	8.52e-04	346	94	6	EFO_0004337, EFO_0004784, MONDO_0005090
Disease	response to 5-fluorouracil, response to cyclophosphamide, chemotherapy-induced alopecia, response to doxorubicin	SMARCA2 CDH13	8.91e-04	14	94	2	EFO_0005400, GO_0036275, GO_1902518, GO_1902520
Disease	African Burkitt's lymphoma	PIK3R1 SMARCA4	1.03e-03	15	94	2	C0343640
Disease	Burkitt Leukemia	PIK3R1 SMARCA4	1.03e-03	15	94	2	C4721444
Disease	level of Phosphatidylcholine (16:0_16:0) in blood serum	CETP SMARCA4	1.03e-03	15	94	2	OBA_2045067
Disease	parental longevity	GALNT15 GAPVD1 PDE3A MAGI3 SMARCA2 SMARCA4 CDH13	1.03e-03	494	94	7	EFO_0007796
Disease	bacteriemia	DOCK3 MAGI3	1.32e-03	17	94	2	EFO_0003033
Disease	very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	CETP SMARCA4	1.49e-03	18	94	2	EFO_0008317, EFO_0008589
Disease	prostate cancer (is_marker_for)	PIK3R1 SMARCA2 SMARCA4 KMT2A	1.58e-03	156	94	4	DOID:10283 (is_marker_for)
Disease	sodium-coupled monocarboxylate transporter 1 measurement	CETP SMARCA4	1.66e-03	19	94	2	EFO_0802076
Disease	Alcoholic Intoxication, Chronic	TIPARP SPG21 PIK3R1 GLI2 CDH13	1.69e-03	268	94	5	C0001973
Disease	cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage	CETP SMARCA4	2.03e-03	21	94	2	EFO_0022246
Disease	hemoglobin change measurement	KMT2A CDH13	2.23e-03	22	94	2	EFO_0600027
Disease	phosphatidylcholine 34:3 measurement	CETP METTL4	2.23e-03	22	94	2	EFO_0010377
Disease	Bronchiectasis	PIK3R1 CCDC40	2.23e-03	22	94	2	C0006267
Disease	myeloid white cell count	FKBP15 PDE3A PIK3R3 RMI1 POLI ZFHX3 RMC1 NUP160 ZNF292	3.02e-03	937	94	9	EFO_0007988
Disease	Antiglaucoma preparations and miotics use measurement	KMT2A NUP160	3.10e-03	26	94	2	EFO_0009944
Disease	colon adenocarcinoma (is_implicated_in)	PIK3R3 CHD4	3.10e-03	26	94	2	DOID:234 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
EDYAISHHLTKIQQQ	ANKRD20A1	236	Q5TYW2
NIHKIYHTLNKLNLT	DCUN1D4	21	Q92564
QVKYGLHNIQISHLS	CETP	71	P11597
EDYAISHHLTKIQQQ	ANKRD20A8P	236	Q5CZ79
VFKHLQQDILQHTQT	TBC1D32	1196	Q96NH3
EDYAISHHLTKIQQQ	ANKRD20A4P	236	Q4UJ75
HIAAHYENLNVAQLL	ANK1	211	P16157
NKVKVLHNQLVLFHN	ARFIP1	321	P53367
IVQNAVVYVLNHNHH	CFAP46	736	Q8IYW2
QYHQLLVSVDQKHLF	DOP1A	1741	Q5JWR5
HALVSLLQNLNKANY	CDH13	641	P55290
HEVYLQVLTKNKDNH	DCP1A	566	Q9NPI6
LVNQLQYHTHQENGI	TIPARP	226	Q7Z3E1
QNQVLLHKHLNLFLT	ITPR2	1251	Q14571
HNIYILALQLSRHNK	ITPR3	2051	Q14573
KHHQGTYNLTVQILN	KIAA1549	1081	Q9HCM3
EDYAISHHLTKIQQQ	ANKRD20A2P	236	Q5SQ80
EIYHQNVQNLTHLQV	MAGI3	621	Q5TCQ9
HHVVVIQNQTLIKAY	EYS	3066	Q5T1H1
IVQNILGNEHQHLYA	NEK1	1226	Q96PY6
NNLYQTALHLAVHLD	NFKBIE	291	O00221
AHLLQYNHRVKKLNE	LGALS3	216	P17931
HHLKQERLYVNSEKQ	GAPVD1	11	Q14C86
QQQYLQHTSRKEIHF	GALNT15	541	Q8N3T1
FERNYKSHHLQLQVI	CWF19L1	406	Q69YN2
IYCQITQHLLQNHKM	PDE3A	1071	Q14432
HLLASAKDEHLQQYQ	FKBP15	811	Q5T1M5
LGQLYFEHLQILHKQ	GANC	156	Q8TET4
HQTLLKTLNAVQYHH	LACC1	21	Q8IV20
IHAVKELNLQEYRQH	LRP6	1191	O75581
KEYDTQEQLVHHINN	GLI2	446	P10070
HASNILHKQLLNNIL	ABCC2	1051	Q92887
THNYQIVNHDQKLLL	KBTBD7	556	Q8WVZ9
LSQYQLNSIQKNHVH	PARP4	56	Q9UKK3
LKELVLHYQHTSLVQ	PIK3R1	691	P27986
QRQHDQLEAQKLEYH	NUCB2	376	P80303
ALEQQRHHEKKSIYN	NOP14	106	P78316
KLLQALAQYQNHLQE	MYBBP1A	161	Q9BQG0
VALKYQQHQESLSAQ	GOLIM4	46	O00461
YISHQHQKLVVSKQN	PCID2	376	Q5JVF3
KELVLHYQQTSLVQH	PIK3R3	426	Q92569
EDYAISHHLTKIQQQ	ANKRD20A3P	236	Q5VUR7
IAQELYHKRHVETNQ	IGSF6	206	O95976
NLNHLNQFVDHEKIY	IDI1	211	Q13907
SQYQHKQVHGNINLL	DOCK3	1526	Q8IZD9
LKNSKYQLLHHSANQ	CRTAM	66	O95727
YSAQHEIRHNIQKEL	GALNT3	546	Q14435
LFTSHHYNHQLLKQQ	DHX57	976	Q6P158
HYNHQLLKQQLPEIQ	DHX57	981	Q6P158
QVHFQFLTHALQKVQ	GARRE1	176	O15063
LYEVQQHLVHLQKLL	CCDC40	331	Q4G0X9
THIKLQEHYNKLCNQ	CCDC73	371	Q6ZRK6
YLENTNVNISHLHLN	CCDC73	766	Q6ZRK6
ENLLANVYHQINHLK	IFNB1	106	P01574
NVYHQINHLKTVLEE	IFNB1	111	P01574
ADEHYQLQHVNQLLA	KMT2A	3446	Q03164
NHLIHLSNTNNVKLL	EXOC1	256	Q9NV70
HTDAYLQHLQKVSQE	HDAC8	71	Q9BY41
KLLRHHYEQQQEDLA	CHD4	1316	Q14839
HVYNNQSINLLDVLH	POLI	181	Q9UNA4
TQNLVLYNITKHHVT	CFAP47	1216	Q6ZTR5
LSFINKINYQLHQHH	METTL4	16	Q8N3J2
YRKLHHLQVIILDNN	LRCH2	266	Q5VUJ6
YELISQLHQHVQQLH	RASL11B	126	Q9BPW5
VQQVHQDILAAYKLH	SYNC	211	Q9H7C4
LVYHQNEIVQSLKTH	UTP20	81	O75691
LKHFIHVLQTGQINQ	UTP20	1656	O75691
FHTYLNHLIQGLQKE	STARD13	906	Q9Y3M8
KHHILQIFQQITENL	TEX55	506	Q96M34
ALHHLTVHNIAYQLQ	QTRT1	341	Q9BXR0
QKHQEYLNSILQHAK	SMARCA2	446	P51531
HKEYLEQHSRQLQEQ	TMEM191C	136	A6NGB0
HSLNNKILNREVVNY	RMI1	436	Q9H9A7
LHVLAQQQYEQLTHA	NSUN7	411	Q8NE18
NIQKYSHLQLAQQEH	NIPAL2	66	Q9H841
GLLKKNYLNQHIEHV	ERCC5	236	P28715
LLGNIQLYHQTQHTQ	PRSS47P	136	A8MTI9
KHQEYLNSILQHAKD	SMARCA4	471	P51532
NLYVQIHLLQFHGTK	SPG21	266	Q9NZD8
VQNNLYHHCVINKLL	NUP160	1301	Q12769
QEKLHVNYLTSLHLQ	ARID5B	876	Q14865
FNNVYQLTLHQKIHT	ZNF540	196	Q8NDQ6
RVTHLYQLKQHNILA	VPS11	86	Q9H270
EQVHHIVKQALQRYS	SUN2	526	Q9UH99
ELKVTYSSNHHLQQQ	SLITRK5	781	O94991
NQFQIAVQHYLHELV	RMC1	491	Q96DM3
FQLYHNEKKIHLLNT	SMC1B	226	Q8NDV3
HNELNAHIKLSNLYK	TPR	276	P12270
QLNNVLEHLVFHKTQ	TMEM232	281	C9JQI7
TIQQNLILHYQAVHK	ZNF292	2126	O60281
NLNIHQKIHTGERQY	ZNF585B	536	Q52M93
SHLHSNHLYIKQQQQ	USF3	1451	Q68DE3
HIFYRHDLINQLQQN	USP9Y	596	O00507
QKQHDHYLRQQEILE	TTC17	366	Q96AE7
QKHEAAINLYHQVLE	TTC21A	971	Q8NDW8
LTQHHKIQTLLQTFQ	ZNF717	196	Q9BY31
KTHRYELAQQLQQHQ	ZNF236	761	Q9UL36
AFNVNAKLIQHQRIH	ZNF23	316	P17027
SELILAQQQQHKKYH	TMEM127	151	O75204
TLIQHQQIHTGEKLY	ZNF850	771	A8MQ14
AVIRHEVNYQNVVHK	ZMYM4	451	Q5VZL5
QKNILLVHYNSVSHL	ZFHX3	1556	Q15911
LILKSHQEHVHQNYF	ZFHX3	1996	Q15911
HKQQVQHICRNNLYP	VN1R2	291	Q8NFZ6
KVKHLLYEHQNNLTE	GAS8	101	O95995
LNSEKHRLINYHQEQ	AGL	381	P35573
VLAQHNTKQLSDLNY	NEB	1491	P20929