Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK2 DOCK3 DOCK4 PSD3 TIAM2 PLEKHG1 RCC1L HERC1 MCF2L SOS1

2.44e-0623112810GO:0005085
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

SETD1A ASH1L KMT2E EZH2

1.79e-04441284GO:0140938
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK2 DOCK3 DOCK4 PSD3 TIAM2 PLEKHG1 RCC1L HERC1 MCF2L ARAP2 SOS1

4.27e-0450712811GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK2 DOCK3 DOCK4 PSD3 TIAM2 PLEKHG1 RCC1L HERC1 MCF2L ARAP2 SOS1

4.27e-0450712811GO:0030695
GeneOntologyMolecularFunctionmethyltransferase activity

SETD1A ASH1L KMT2E EZH2 PRDM5 PRDM10 TRMT13

4.52e-042131287GO:0008168
GeneOntologyMolecularFunctionchromo shadow domain binding

SP100 NIPBL

6.01e-0461282GO:0070087
GeneOntologyMolecularFunctiontransferase activity, transferring one-carbon groups

SETD1A ASH1L KMT2E EZH2 PRDM5 PRDM10 TRMT13

6.10e-042241287GO:0016741
GeneOntologyMolecularFunctionhistone modifying activity

SETD1A ASH1L BAZ1B KMT2E EZH2 KAT6B USP3

6.95e-042291287GO:0140993
DomainSET_dom

SETD1A ASH1L KMT2E EZH2 PRDM5 PRDM10

1.04e-06501266IPR001214
DomainSET

SETD1A ASH1L KMT2E EZH2 PRDM5 PRDM10

1.04e-06501266PS50280
DomainSpectrin_repeat

SPTAN1 SPTB PPL DST MCF2L

1.35e-06291265IPR002017
DomainSPEC

SPTAN1 SPTB PPL DST MCF2L

2.25e-06321265SM00150
DomainSpectrin/alpha-actinin

SPTAN1 SPTB PPL DST MCF2L

2.25e-06321265IPR018159
DomainDOCK_N

DOCK2 DOCK3 DOCK4

2.97e-0651263PF16172
DomainDOCK_N

DOCK2 DOCK3 DOCK4

2.97e-0651263IPR032376
DomainKRAB

ZNF845 ZNF141 ZNF157 ZFP57 ZNF510 ZNF568 ZNF587B ZNF675 ZNF432 ZNF808 ZNF264 ZNF81

5.62e-0635812612PS50805
DomainKRAB

ZNF845 ZNF141 ZNF157 ZFP57 ZNF510 ZNF568 ZNF587B ZNF675 ZNF432 ZNF808 ZNF264 ZNF81

5.62e-0635812612PF01352
DomainKRAB

ZNF845 ZNF141 ZNF157 ZFP57 ZNF510 ZNF568 ZNF587B ZNF675 ZNF432 ZNF808 ZNF264 ZNF81

7.63e-0636912612SM00349
DomainKRAB

ZNF845 ZNF141 ZNF157 ZFP57 ZNF510 ZNF568 ZNF587B ZNF675 ZNF432 ZNF808 ZNF264 ZNF81

7.84e-0637012612IPR001909
DomainSET

SETD1A ASH1L KMT2E EZH2 PRDM5

7.96e-06411265PF00856
Domain-

ZNF845 ZNF141 ZNF157 ZFP57 ZNF696 ZNF510 PRDM5 ZNF568 ZNF587B ZIC2 ZNF675 PRDM10 ZNF432 ZNF808 ZNF264 ZNF81

1.35e-05679126163.30.160.60
DomainSET

SETD1A ASH1L KMT2E EZH2 PRDM5

1.42e-05461265SM00317
DomainSpectrin

SPTAN1 SPTB DST MCF2L

1.58e-05231264PF00435
Domainzf-C2H2

ZNF845 ZNF141 ZNF157 ZFP57 ZNF696 ZNF510 PRDM5 ZNF568 ZNF587B ZIC2 ZNF675 PRDM10 ZNF432 ZNF808 ZNF264 ZNF81

1.74e-0569312616PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF845 ZNF141 ZNF157 ZFP57 ZNF696 ZNF510 PRDM5 ZNF568 ZNF587B ZIC2 ZNF675 PRDM10 ZNF432 ZNF808 ZNF264 ZNF81

1.77e-0569412616IPR013087
DomainZINC_FINGER_C2H2_2

ZNF845 ZNF141 ZNF157 ZFP57 ZNF696 ZNF510 PRDM5 ANKZF1 ZNF568 ZNF587B ZIC2 ZNF675 PRDM10 ZNF432 ZNF808 ZNF264 ZNF81

1.80e-0577512617PS50157
DomainZINC_FINGER_C2H2_1

ZNF845 ZNF141 ZNF157 ZFP57 ZNF696 ZNF510 PRDM5 ANKZF1 ZNF568 ZNF587B ZIC2 ZNF675 PRDM10 ZNF432 ZNF808 ZNF264 ZNF81

1.86e-0577712617PS00028
DomainZnf_C2H2-like

ZNF845 ZNF141 ZNF157 ZFP57 ZNF696 ZNF510 PRDM5 ANKZF1 ZNF568 ZNF587B ZIC2 ZNF675 PRDM10 ZNF432 ZNF808 ZNF264 ZNF81

2.53e-0579612617IPR015880
DomainZnf_C2H2

ZNF845 ZNF141 ZNF157 ZFP57 ZNF696 ZNF510 PRDM5 ANKZF1 ZNF568 ZNF587B ZIC2 ZNF675 PRDM10 ZNF432 ZNF808 ZNF264 ZNF81

2.91e-0580512617IPR007087
DomainZnF_C2H2

ZNF845 ZNF141 ZNF157 ZFP57 ZNF696 ZNF510 PRDM5 ANKZF1 ZNF568 ZNF587B ZIC2 ZNF675 PRDM10 ZNF432 ZNF808 ZNF264 ZNF81

3.05e-0580812617SM00355
DomainDHR-1_domain

DOCK2 DOCK3 DOCK4

4.75e-05111263IPR027007
DomainDHR_2

DOCK2 DOCK3 DOCK4

4.75e-05111263PS51651
DomainDHR_1

DOCK2 DOCK3 DOCK4

4.75e-05111263PS51650
DomainDHR-2

DOCK2 DOCK3 DOCK4

4.75e-05111263PF06920
DomainDOCK

DOCK2 DOCK3 DOCK4

4.75e-05111263IPR026791
DomainDOCK_C

DOCK2 DOCK3 DOCK4

4.75e-05111263IPR010703
DomainDOCK-C2

DOCK2 DOCK3 DOCK4

4.75e-05111263PF14429
DomainDHR-2

DOCK2 DOCK3 DOCK4

4.75e-05111263IPR027357
DomainSH3

DOCK2 DOCK3 DOCK4 MYO7B SPTAN1 ITK DST MCF2L

1.10e-042161268PS50002
DomainSH3_domain

DOCK2 DOCK3 DOCK4 MYO7B SPTAN1 ITK DST MCF2L

1.25e-042201268IPR001452
DomainGDS_CDC24_CS

TIAM2 PLEKHG1 MCF2L SOS1

1.35e-04391264IPR001331
Domainzf-C2H2_6

ZNF845 ZNF141 ZNF157 PRDM5 ZNF568 ZNF675 PRDM10 ZNF432 ZNF808

2.82e-043141269PF13912
DomainSH3_2

DOCK2 DOCK3 DOCK4 MYO7B MCF2L

2.90e-04861265PF07653
DomainSH3_2

DOCK2 DOCK3 DOCK4 MYO7B MCF2L

2.90e-04861265IPR011511
DomainSH3

DOCK2 DOCK3 DOCK4 MYO7B SPTAN1 ITK MCF2L

6.63e-042161267SM00326
DomainDH_1

TIAM2 PLEKHG1 MCF2L SOS1

8.65e-04631264PS00741
DomainArm_3

KPNA2 KPNA3

9.27e-0471262PF16186
DomainImporting_su_alpha

KPNA2 KPNA3

9.27e-0471262IPR024931
DomainPlectin

PPL DST

9.27e-0471262PF00681
DomainIBB

KPNA2 KPNA3

9.27e-0471262PF01749
DomainPlectin_repeat

PPL DST

9.27e-0471262IPR001101
DomainArm_3

KPNA2 KPNA3

9.27e-0471262IPR032413
DomainPLEC

PPL DST

9.27e-0471262SM00250
DomainPH

PSD3 ITK TIAM2 PLEKHG1 MCF2L ARAP2 SOS1

9.34e-042291267PF00169
DomainRhoGEF

TIAM2 PLEKHG1 MCF2L SOS1

1.15e-03681264SM00325
DomainIBB

KPNA2 KPNA3

1.23e-0381262PS51214
DomainRhoGEF

TIAM2 PLEKHG1 MCF2L SOS1

1.28e-03701264PF00621
DomainDH_2

TIAM2 PLEKHG1 MCF2L SOS1

1.28e-03701264PS50010
Domain-

TIAM2 PLEKHG1 MCF2L SOS1

1.35e-037112641.20.900.10
DomainDH-domain

TIAM2 PLEKHG1 MCF2L SOS1

1.35e-03711264IPR000219
Domain-

EHBP1 SPTB DST CAMSAP2

1.35e-037112641.10.418.10
DomainCH

EHBP1 SPTB DST CAMSAP2

1.50e-03731264PS50021
DomainImportin-a_IBB

KPNA2 KPNA3

1.58e-0391262IPR002652
DomainPHD

ASH1L BAZ1B KMT2E KAT6B

1.66e-03751264PF00628
DomainCH-domain

EHBP1 SPTB DST CAMSAP2

1.66e-03751264IPR001715
DomainZnf_PHD-finger

ASH1L BAZ1B KMT2E KAT6B

2.01e-03791264IPR019787
DomainARM-type_fold

DOCK2 DOCK3 NEK10 MTOR RRP12 NIPBL KPNA2 KPNA3

2.13e-033391268IPR016024
DomainBAH

ASH1L TNRC18

2.39e-03111262PS51038
DomainBAH_dom

ASH1L TNRC18

2.39e-03111262IPR001025
DomainBAH

ASH1L TNRC18

2.39e-03111262SM00439
DomainBAH

ASH1L TNRC18

2.39e-03111262PF01426
DomainARM-like

DOCK2 NEK10 MTOR RRP12 NIPBL KPNA2 KPNA3

2.39e-032701267IPR011989
DomainARM_REPEAT

NEK10 KPNA2 KPNA3

2.47e-03401263PS50176
DomainPH

PSD3 ITK TIAM2 PLEKHG1 MCF2L ARAP2 SOS1

2.81e-032781267SM00233
DomainPH_DOMAIN

PSD3 ITK TIAM2 PLEKHG1 MCF2L ARAP2 SOS1

2.87e-032791267PS50003
DomainPH_domain

PSD3 ITK TIAM2 PLEKHG1 MCF2L ARAP2 SOS1

2.93e-032801267IPR001849
DomainPHD

ASH1L BAZ1B KMT2E KAT6B

3.10e-03891264SM00249
DomainZnf_FYVE_PHD

ASH1L BAZ1B KMT2E KAT6B RUFY4

3.21e-031471265IPR011011
DomainZnf_PHD

ASH1L BAZ1B KMT2E KAT6B

3.36e-03911264IPR001965
DomainEF-hand_1

SPTAN1 S100A12 PPP2R3A DST SLC25A12

3.71e-031521265PF00036
DomainZF_PHD_2

ASH1L BAZ1B KMT2E KAT6B

3.92e-03951264PS50016
Domain-

NEK10 MTOR RRP12 NIPBL KPNA2 KPNA3

3.98e-0322212661.25.10.10
DomainZF_PHD_1

ASH1L BAZ1B KMT2E KAT6B

4.07e-03961264PS01359
DomainSpectrin_alpha_SH3

SPTAN1 ITK

4.48e-03151262IPR013315
Domain-

MYO7B PSD3 ITK TIAM2 PLEKHG1 MCF2L ARAP2 SOS1

5.06e-0339112682.30.29.30
DomainPost-SET_dom

SETD1A ASH1L

5.09e-03161262IPR003616
DomainPostSET

SETD1A ASH1L

5.09e-03161262SM00508
DomainHSP70

HSPA6 HSPA7

5.09e-03161262PF00012
DomainPOST_SET

SETD1A ASH1L

5.09e-03161262PS50868
DomainHSP70_2

HSPA6 HSPA7

5.75e-03171262PS00329
DomainHSP70_1

HSPA6 HSPA7

5.75e-03171262PS00297
DomainHSP70_3

HSPA6 HSPA7

5.75e-03171262PS01036
DomainHsp_70_fam

HSPA6 HSPA7

6.44e-03181262IPR013126
PathwayREACTOME_RAC1_GTPASE_CYCLE

DOCK2 DOCK4 RBM39 TIAM2 PLEKHG1 MCF2L ARAP2 SOS1

2.16e-05175948MM15599
PathwayREACTOME_RAC1_GTPASE_CYCLE

DOCK2 DOCK3 DOCK4 TIAM2 PLEKHG1 MCF2L ARAP2 SOS1

3.09e-05184948M41809
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

MBTD1 ZNF845 ARID4A BAZ1B EZH2 PRPF8 INTS3 PQBP1 INO80D RBM39 ZZZ3 DST PRPF3 SUPT6H RRP12 CPSF1 USP3 NIPBL HSPA6 KPNA2

6.70e-0812941292030804502
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MBTD1 SP100 NOL12 ASH1L BAZ1B RSRC2 ANKHD1 PRDM5 INO80D ZIC2 ZZZ3 SLC25A12 PRPF3 PANK4 KAT6B ARAP2 SOS1 KPNA3

1.74e-0711161291831753913
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

EHBP1 RPAP3 SPTAN1 PRPF8 INTS3 RBM39 PRPF3 SUPT6H HSPA6 KPNA2 KPNA3

2.50e-073901291117643375
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SP100 TRO SPTAN1 ASH1L PRPF8 PPL TASOR2 GPALPP1 ZNF675 TNRC18 DST SLC25A12 FAM161A MCF2L TNNT1 CAMSAP2 DNAH8 NIPBL HSPA6 MYBPC2

3.76e-0714421292035575683
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DOCK3 SETD1A LAD1 SMG5 ANKHD1 TIAM2 PLEKHG1 TNRC18 DST PTPRF PTPRS MTOR RRP12 C19orf44 CPSF1 HERC1 MCF2L

7.58e-0711051291735748872
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

NOL12 BAZ1B EZH2 PPL PRPF3 RRP12 NIPBL KPNA2

1.26e-06210129816565220
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RPAP3 GOLM2 SPTAN1 PSD3 FAM171B PQBP1 PPP2R3A PTPRF PRPF3 PTPRS RRP12 CPSF1 HERC1 HSPA6 KPNA2 KPNA3

1.84e-0610491291627880917
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DOCK2 KIF27 SPTAN1 PRPF8 INTS3 RBM39 PRPF3 MED12L CPSF1 NIPBL HSPA6 KPNA2

1.91e-065821291220467437
Pubmed

New nomenclature for chromatin-modifying enzymes.

SETD1A ASH1L KMT2E EZH2 KAT6B

2.33e-0657129518022353
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

EHBP1 KCNH8 GOLM2 SPTB ASH1L DYNC2I1 INTS3 RBM39 TASOR2 PPP2R3A TNRC18 PRPF3 PTPRS SUPT6H PANK4 TRMT13 MCF2L KAT6B USP3

2.59e-0614891291928611215
Pubmed

Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.

SETD1A ASH1L KMT2E

2.75e-068129323130995
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

DOCK3 SETD1A CCPG1 TRO KMT2E TASOR2 TNRC18 SOS1 KPNA2 KPNA3

5.00e-064301291035044719
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

SPTAN1 BAZ1B ANKHD1 PRPF8 RBM39 TASOR2 DST MTOR SUPT6H RRP12 CPSF1 NIPBL

6.16e-066531291222586326
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

OR2F2 MBTD1 ARID4A EZH2 PAPSS2 PQBP1 INO80D RBM39 XYLT2 RCC1L PRDM10 CPSF1 USP3 NIPBL SOS1 KPNA2 KPNA3

8.74e-0613271291732694731
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

DOCK3 DOCK4 SPTAN1 SPTB FAM171B DLGAP3 CAMSAP2

9.38e-06197129736604605
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SETD1A RPAP3 SPTAN1 BAZ1B ANKHD1 PRPF8 PAPSS2 RBM39 DST SLC25A12 PRPF3 RRP12 CPSF1 USP3 NIPBL HSPA6 KPNA3

1.12e-0513531291729467282
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SPTAN1 NOL12 RSRC2 PRPF8 RBM39 DST SLC25A12 PRPF3 SUPT6H RRP12 CPSF1 NIPBL HSPA6 KPNA2 KPNA3

1.23e-0510821291538697112
Pubmed

Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch1alpha).

ITK KPNA2

1.37e-052129211581171
Pubmed

mTOR regulates proteasomal degradation and Dp1/E2F1- mediated transcription of KPNA2 in lung cancer cells.

MTOR KPNA2

1.37e-052129227009856
Pubmed

Variations in both α-spectrin (SPTA1) and β-spectrin ( SPTB ) in a neonate with prolonged jaundice in a family where nine individuals had hereditary elliptocytosis.

SPTAN1 SPTB

1.37e-052129224193021
Pubmed

Importin-alpha mediates the regulated nuclear targeting of serum- and glucocorticoid-inducible protein kinase (Sgk) by recognition of a nuclear localization signal in the kinase central domain.

SGK1 KPNA2

1.37e-052129212631736
Pubmed

Cleavage stage porcine embryos may have differing developmental requirements for karyopherins alpha2 and alpha3.

KPNA2 KPNA3

1.37e-052129212548662
Pubmed

Loss of tumor suppressor IGFBP4 drives epigenetic reprogramming in hepatic carcinogenesis.

EZH2 IGFBP4

1.37e-052129229992318
Pubmed

The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1.

HSPA6 HSPA7

1.37e-05212921346391
Pubmed

The tumor-suppressor gene LZTS1 suppresses colorectal cancer proliferation through inhibition of the AKT-mTOR signaling pathway.

LZTS1 MTOR

1.37e-052129225667121
Pubmed

Interactions of the alpha-spectrin N-terminal region with beta-spectrin. Implications for the spectrin tetramerization reaction.

SPTAN1 SPTB

1.37e-05212929890967
Pubmed

The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family.

DOCK2 DOCK3 DOCK4

1.39e-0513129321930703
Pubmed

Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.

ZNF568 ZNF264 NIPBL KPNA2 KPNA3

1.50e-0583129520562864
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK2 DOCK3 DOCK4

1.76e-0514129312432077
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

MBTD1 KIF27 ARID4A TRO SMG5 RSRC2 ANKHD1 PRPF8 INTS3 ZIC2 PRDM10 PANK4 KPNA2

1.92e-058571291325609649
Pubmed

Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.

ZZZ3 PRPF3 FAM161A HERC1 NIPBL KPNA2

2.06e-05149129625184681
Pubmed

Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex.

HSPA6 KPNA2 KPNA3

2.20e-0515129310964507
Pubmed

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.

NOL12 ZNF696 PRPF8 RCC1L PRDM10 PRPF3 RRP12 CPSF1 KPNA2

2.71e-05417129936537216
Pubmed

Nucleolar proteome dynamics.

BAZ1B PQBP1 RBM39 PRPF3 RRP12 MPHOSPH6 NIPBL KPNA2 KPNA3

2.82e-05419129915635413
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SETD1A SMG5 ANKHD1 TIAM2 TRANK1 DST SUPT6H MED12L KAT6B KCNT1

2.98e-055291291014621295
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DOCK2 DOCK3 DOCK4 RBM39 TIAM2 PLEKHG1 SLC25A12 PRPF3 CPSF1 MCF2L ARAP2 SOS1 KPNA2

3.82e-059161291332203420
Pubmed

LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.

PTPRF PTPRS

4.09e-053129231985401
Pubmed

Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.

PTPRF PTPRS

4.09e-053129220139422
Pubmed

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.

PTPRF PTPRS

4.09e-053129233656439
Pubmed

Mutations in the pre-mRNA splicing-factor genes PRPF3, PRPF8, and PRPF31 in Spanish families with autosomal dominant retinitis pigmentosa.

PRPF8 PRPF3

4.09e-053129212714658
Pubmed

Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway.

EZH2 MTOR

4.09e-053129226735435
Pubmed

mTOR complex-2 activates ENaC by phosphorylating SGK1.

SGK1 MTOR

4.09e-053129220338997
Pubmed

mSIN1 protein mediates SGK1 protein interaction with mTORC2 protein complex and is required for selective activation of the epithelial sodium channel.

SGK1 MTOR

4.09e-053129221757730
Pubmed

Mutations in pre-mRNA processing factors 3, 8, and 31 cause dysfunction of the retinal pigment epithelium.

PRPF8 PRPF3

4.09e-053129225111227
Pubmed

The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulation.

SETD1A SUPT6H

4.09e-053129222843687
Pubmed

Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.

PTPRF PTPRS

4.09e-05312929784606
Pubmed

MLL5, a histone modifying enzyme, regulates androgen receptor activity in prostate cancer cells by recruiting co-regulators, HCF1 and SET1.

SETD1A KMT2E

4.09e-053129233050986
Pubmed

Pseudoxanthoma Elasticum

ABCC6 XYLT2

4.09e-053129220301292
Pubmed

Mapping the binding sites of human erythrocyte ankyrin for the anion exchanger and spectrin.

SPTAN1 SPTB

4.09e-05312922141335
Pubmed

mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity.

SGK1 MTOR

4.09e-053129225415435
Pubmed

Potassium acts through mTOR to regulate its own secretion.

SGK1 MTOR

4.09e-053129231013253
Pubmed

PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa.

PRPF8 PRPF3

4.09e-053129221378395
Pubmed

The complete amino acid sequence for brain beta spectrin (beta fodrin): relationship to globin sequences.

SPTAN1 SPTB

4.09e-05312928479293
Pubmed

Three gene-targeted mouse models of RNA splicing factor RP show late-onset RPE and retinal degeneration.

PRPF8 PRPF3

4.09e-053129220811066
Pubmed

Developmental expression of brain beta-spectrin isoform messenger RNAs.

SPTAN1 SPTB

4.09e-05312921467942
Pubmed

The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins.

EZH2 SUPT6H

4.09e-053129229033324
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

DOCK3 SETD1A TRANK1 MCF2L KAT6B

4.45e-0510412959205841
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

SPTAN1 SPTB LAD1 ANKHD1 PPL DST PRPF3 NIPBL

6.27e-05360129833111431
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

SETD1A ZNF157 EZH2 INTS3 PQBP1 TASOR2 SUPT6H KPNA2 KPNA3

6.71e-05469129927634302
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

SPTAN1 PSD3 SMG5 RBM39 GPALPP1 SUPT6H MCF2L KCNT1 KPNA3

7.39e-05475129931040226
Pubmed

A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein.

RPAP3 PRPF8 HSPA6 HSPA7

8.00e-0561129419875381
Pubmed

MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection.

KPNA2 KPNA3

8.15e-054129229370303
Pubmed

Dynamic changes in the expression of protein tyrosine phosphatases during preimplantation mouse development: semi-quantification by real-time PCR.

PTPRF PTPRS

8.15e-054129214967925
Pubmed

FOXM1-regulated ZIC2 promotes the malignant phenotype of renal clear cell carcinoma by activating UBE2C/mTOR signaling pathway.

ZIC2 MTOR

8.15e-054129237496990
Pubmed

Protein Tyrosine Phosphatase PTPRS Is an Inhibitory Receptor on Human and Murine Plasmacytoid Dendritic Cells.

PTPRF PTPRS

8.15e-054129226231120
Pubmed

The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.

PTPRF PTPRS

8.15e-05412928524829
Pubmed

Viral and cellular requirements for the nuclear entry of retroviral preintegration nucleoprotein complexes.

KPNA2 KPNA3

8.15e-054129224103892
Pubmed

Identification of the spectrin subunit and domains required for formation of spectrin/adducin/actin complexes.

SPTAN1 SPTB

8.15e-05412928663089
Pubmed

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.

SPTAN1 SPTB

8.15e-054129221566095
Pubmed

Remarkable homology among the internal repeats of erythroid and nonerythroid spectrin.

SPTAN1 SPTB

8.15e-05412923862089
Pubmed

Phospholipase D stabilizes HDM2 through an mTORC2/SGK1 pathway.

SGK1 MTOR

8.15e-054129220438709
Pubmed

Plasma membrane-cytoskeleton-endoplasmic reticulum complexes in neurons and astrocytes.

SPTAN1 SPTB

8.15e-054129214593108
Pubmed

Nuclear trafficking of the POZ-ZF protein Znf131.

KPNA2 KPNA3

8.15e-054129217306895
Pubmed

Spectrin alpha II and beta II isoforms interact with high affinity at the tetramerization site.

SPTAN1 SPTB

8.15e-054129212820899
Pubmed

PRPF19 regulates p53-dependent cellular senescence by modulating alternative splicing of MDM4 mRNA.

PRPF8 PRPF3

8.15e-054129234144037
Pubmed

Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.

SETD1A ZZZ3 NIPBL HSPA6 KPNA3

8.46e-05119129523508102
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

RSRC2 PRPF8 PQBP1 RBM39 PRPF3 RRP12 CPSF1 MPHOSPH6 HSPA6 KPNA2 KPNA3

9.26e-057311291129298432
Pubmed

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.

SPTAN1 SPTB SOS1

1.08e-042512938493579
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

ZNF157 EZH2 PQBP1 ZIC2 PPP2R3A PRPF3 RRP12 KPNA2

1.21e-04396129826687479
Pubmed

Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos.

SETD1A SPTAN1 DYNC2I1

1.22e-0426129337228654
Pubmed

Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.

ANKHD1 PRPF8 RBM39 RRP12 CPSF1

1.24e-04129129528973437
Pubmed

KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.

RSRC2 PRPF8 GPALPP1 PRPF3 CPSF1

1.28e-04130129535545047
Pubmed

Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPs.

PTPRF PTPRS

1.36e-045129210777529
Pubmed

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).

SGK1 MTOR

1.36e-045129218925875
Pubmed

Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal.

KPNA2 KPNA3

1.36e-045129219961612
Pubmed

Neutral sphingomyelinase 2 deficiency increases hyaluronan synthesis by up-regulation of Hyaluronan synthase 2 through decreased ceramide production and activation of Akt.

MTOR SMPD3

1.36e-045129222383528
Pubmed

The 65 and 110 kDa SR-related proteins of the U4/U6.U5 tri-snRNP are essential for the assembly of mature spliceosomes.

PRPF8 PRPF3

1.36e-045129211350945
Pubmed

Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule.

PTPRF PTPRS

1.36e-045129222357843
Pubmed

Identification of novel homologues of mouse importin alpha, the alpha subunit of the nuclear pore-targeting complex, and their tissue-specific expression.

KPNA2 KPNA3

1.36e-04512929369227
Pubmed

Nuclear localization of Duplin, a beta-catenin-binding protein, is essential for its inhibitory activity on the Wnt signaling pathway.

KPNA2 KPNA3

1.36e-045129211744694
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK4 TRO PSD3 PLEKHG1 RRP12 MCF2L CAMSAP2 ARAP2

1.46e-04407129812693553
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ARID4A SPTAN1 BAZ1B EZH2 INTS3 PPL RRP12 CPSF1 KAT6B NIPBL SOS1

1.52e-047741291115302935
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

SP100 ZNF845 GOLM2 ZNF696 BAZ1B KMT2E PRPF8 INTS3 ZNF587B DLGAP3 PTPRF RRP12 ZNF808 USP3

1.57e-0412031291429180619
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

EHBP1 RPAP3 BAZ1B ANKHD1 PRPF8 RBM39 GPALPP1 DST PRPF3 RRP12 CAMSAP2 NIPBL

1.94e-049341291233916271
Pubmed

Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import.

KPNA2 KPNA3

2.03e-04612928551560
Pubmed

Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases.

PTPRF PTPRS

2.03e-046129219273906
Pubmed

Retinoblastoma-binding Protein 4-regulated Classical Nuclear Transport Is Involved in Cellular Senescence.

KPNA2 KPNA3

2.03e-046129226491019
Pubmed

p17 and p17-containing gag precursors of input human immunodeficiency virus are transported into the nuclei of infected cells.

KPNA2 KPNA3

2.03e-04612922064827
Pubmed

Backbone cyclic peptide, which mimics the nuclear localization signal of human immunodeficiency virus type 1 matrix protein, inhibits nuclear import and virus production in nondividing cells.

KPNA2 KPNA3

2.03e-04612929548947
Pubmed

The putative alpha helix 2 of human immunodeficiency virus type 1 Vpr contains a determinant which is responsible for the nuclear translocation of proviral DNA in growth-arrested cells.

KPNA2 KPNA3

2.03e-04612929557700
Cytoband17q21.33

MBTD1 CHAD XYLT2

2.14e-0441129317q21.33
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF845 ZNF141 ZNF157 ZFP57 ZNF696 ZNF510 PRDM5 ANKZF1 ZNF568 ZNF587B ZIC2 ZNF675 PRDM10 ZNF432 ZNF808 ZNF264 ZNF81

4.62e-08718871728
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SPTB PSD3 ITK TIAM2 PLEKHG1 MCF2L ARAP2 SOS1

6.70e-06206878682
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETD1A ASH1L KMT2E EZH2

2.08e-0534874487
GeneFamilyPHD finger proteins

SP100 ASH1L BAZ1B KMT2E KAT6B

7.32e-059087588
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

TIAM2 PLEKHG1 MCF2L SOS1

2.87e-0466874722
GeneFamilyEF-hand domain containing|Spectrins

SPTAN1 SPTB

4.73e-0478721113
GeneFamilyEF-hand domain containing|Plakins

PPL DST

6.29e-048872939
GeneFamilyHeat shock 70kDa proteins

HSPA6 HSPA7

2.97e-0317872583
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

PRDM5 PRDM10

2.97e-03178721197
GeneFamilyArmadillo repeat containing|Importins

KPNA2 KPNA3

3.33e-0318872596
GeneFamilyEF-hand domain containing

SPTAN1 S100A12 PPP2R3A DST SLC25A12

4.12e-03219875863
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRF PTPRS

4.53e-0321872813
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DOCK4 EHBP1 SP100 PDE8A ARID4A PSD3 BAZ1B RBM39 PPP2R3A ZZZ3 DST SLC25A12 KAT6B CAMSAP2 NIPBL ARAP2 SOS1 KPNA3

2.20e-0785612918M4500
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

BAZ1B PRPF8 XYLT2 PRDM10 MED12L HERC1 ARAP2 SOS1

3.18e-061801298M8239
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN

DOCK4 SP100 INTS3 DST SLC25A12 ARAP2

4.02e-06851296M10575
CoexpressionBONOME_OVARIAN_CANCER_POOR_SURVIVAL_UP

CCPG1 PDE8A PSD3 HERC1

1.59e-05311294M816
CoexpressionBONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING

CCPG1 PDE8A LAD1 PSD3 ZNF696 PAPSS2 DST IGFBP4 PTPRS CPSF1 HERC1

4.27e-0550612911M253
CoexpressionGSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN

CCPG1 ARID4A PSD3 PTPRF TRAT1 PRPF3 KPNA3

6.18e-052001297M5073
CoexpressionGSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_52H_UP

MBTD1 SGK1 ZFP57 KMT2E EZH2 RNASE1 PTPRF

6.18e-052001297M9633
CoexpressionGSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_DN

SGK1 SPTAN1 RBM39 ITK MYO3B DNAH8 NIPBL

6.18e-052001297M2936
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 KCNH8 NEK10 PPL PLEKHG1 PTPRF MYO3B ARAP2

8.95e-08191129860ff989fe99d243a3d52955223680cdd1f1917a4
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASH1L RSRC2 KMT2E ANKHD1 RBM39 GSTA4 NIPBL

1.25e-061871297663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ASH1L INO80D RBM39 TASOR2 HERC1 NIPBL ARAP2

1.29e-061881297ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK3 KCNH8 ABCC6 PPL RNASE1 PTPRF MYO3B

1.29e-0618812970d86044bc340e3efb90d0022dd299873639d831c
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 KCNH8 ABCC6 PLEKHG1 PTPRF MYO3B ARAP2

1.34e-0618912977659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 KCNH8 ABCC6 PPL PLEKHG1 PTPRF MYO3B

1.39e-061901297c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

ASH1L RBM39 ITK RRP12 HERC1 USP3 ARAP2

1.49e-06192129747646d7e4990be85072987f92bf18d52f8da752e
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 KCNH8 NEK10 PPL PLEKHG1 MYO3B ARAP2

1.59e-0619412976b286992d4bb56013c0ea5a7601d3476d806175a
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 KCNH8 PPL PLEKHG1 PTPRF MYO3B ARAP2

1.59e-061941297f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

B3GALT2 ARID4A SPTAN1 PSD3 GSTA4 DST RIC3

1.89e-0619912971b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

B3GALT2 ARID4A SPTAN1 PSD3 GSTA4 DST RIC3

1.89e-0619912974bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SP100 ASH1L RSRC2 KMT2E RBM39 NIPBL ARAP2

1.95e-06200129712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellInfluenza_Severe-Treg|Influenza_Severe / Disease group and Cell class

KIF27 ZNF587B TRAT1 TRMT13 MCF2L RIC3

5.86e-06154129677845bcb243aa1b1f1ca00f9ef2ae1b4d1bd3696
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7B ABCC6 ITK XYLT2 TRAT1 DNAH8

7.04e-061591296e967b557fe6ae4879d36f62c0297cbf6a2ad1ce9
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7B ABCC6 ITK XYLT2 TRAT1 DNAH8

7.04e-0615912969db971130509c62d439e0cab16588a4d994d7aa0
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|B_lymphocytes / Location, Cell class and cell subclass

ZFP57 PPP2R3A PTPRS SMPD3 LRRC36 RUFY4

1.26e-051761296d6e660df92a3d7dd5732171ee623763faf108476
ToppCellControl-B_cells-B_cells|Control / group, cell type (main and fine annotations)

DOCK2 SP100 KCNH8 PXK PLEKHG1 DNAH8

1.26e-051761296d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

KIF27 PSD3 ANKHD1 TNRC18 MTOR TRMT13

1.30e-05177129636b5d29caa9cffbc0284f771a4db71aa72171a89
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 ASH1L RSRC2 RBM39 PXK ARAP2

1.52e-051821296eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DOCK3 KCNH8 PPL PLEKHG1 PTPRF ARAP2

1.57e-051831296c5b10571599dc26476170b54b53f09c23e6b3117
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 ASH1L RSRC2 RBM39 PXK ARAP2

1.57e-05183129628cbf909424f3be4491d49832f0aca0386560814
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 ASH1L RSRC2 RBM39 PXK ARAP2

1.57e-0518312963fa608aa6b119869ec3280dc388dfee57160e63a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 PDE8A PSD3 ITK PLEKHG1 DST

1.62e-051841296d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH8 PDE8A ZFP57 RFTN2 PXK RNASE1

1.67e-0518512961d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH8 PDE8A ZFP57 RFTN2 PXK RNASE1

1.72e-05186129690eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH8 PDE8A ZFP57 RFTN2 PXK RNASE1

1.72e-051861296bd8a9753df219084e19e7f94447856e86608325c
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH8 PDE8A ZFP57 RFTN2 PXK RNASE1

1.77e-051871296f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH8 PDE8A ZFP57 RFTN2 PXK RNASE1

1.77e-051871296b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH8 PDE8A ZFP57 RFTN2 PXK RNASE1

1.83e-05188129614072d0b82df55711d5356b2209f4f0bdd90dc27
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-osteoclast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LAD1 RFTN2 PAPSS2 PPL PPP2R3A RUFY4

1.83e-051881296762b52f21d2bc5409f86746a904c4358490be9c0
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 KCNH8 LAD1 PLEKHG1 PTPRF LRRC36

2.06e-051921296d3634574b2e8d2ded6446969361b70761b331aea
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 KCNH8 LAD1 PLEKHG1 PTPRF LRRC36

2.06e-0519212961aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCellPCW_05-06-Epithelial-Epithelial_airway|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DOCK3 KCNH8 PPL PLEKHG1 PTPRF ARAP2

2.12e-051931296af6ec2c2ba92aef3e41531c3c7215b3300437bd9
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DOCK3 KCNH8 PPL PLEKHG1 PTPRF ARAP2

2.18e-051941296b19e16a76d7342ff9a665d19c9151652916f17d4
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 KCNH8 PPL PLEKHG1 PTPRF LRRC36

2.18e-051941296f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK3 KCNH8 PPL RNASE1 PTPRF MYO3B

2.24e-051951296d67a2b489c29bfd575751c13d2a5b1efdec5240a
ToppCellInfluenza-Influenza_Severe-Lymphocyte-T/NK-Treg|Influenza_Severe / Disease, condition lineage and cell class

KIF27 ZNF587B TRAT1 TRMT13 MCF2L RIC3

2.44e-051981296e377fa0215f338f86ee2903ce3fa57cea805a630
ToppCellPCW_10-12-Epithelial-Epithelial_airway|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK3 KCNH8 PPL PTPRF MYO3B ARAP2

2.44e-0519812969a12e5e47236433e512c668005fe3f8be6fde95c
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SP100 ASH1L RBM39 ITK HERC1 ARAP2

2.51e-051991296f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

SP100 ASH1L ITK TRANK1 TRAT1 RIC3

2.51e-051991296952fac67588ad5676f5939e3c7f8bac803c27064
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SPTAN1 ASH1L RNASE1 DST MCF2L NIPBL

2.59e-052001296dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellmedial-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SGK1 PAPSS2 PLEKHG1 RNASE1 IGFBP4 MCF2L

2.59e-052001296a8adf5902540f6bb15b72efbb9c389b59d67e001
ToppCellmedial-Endothelial-Capillary_Intermediate_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SGK1 PAPSS2 PLEKHG1 RNASE1 IGFBP4 MCF2L

2.59e-0520012963ef7b7728615710c691aed8977e2582f19692cf9
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated|COVID-19_Mild / Disease, condition lineage and cell class

SP100 SPTAN1 ITK TRANK1 DST TRAT1

2.59e-052001296d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCellmedial-Endothelial-Capillary_Intermediate_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SGK1 PAPSS2 PLEKHG1 RNASE1 IGFBP4 MCF2L

2.59e-052001296707148e01e961097819a05437a842b7d3bf72b0a
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7B ABCC6 ZIC2 DLGAP3 TRANK1

4.95e-0513712954dcb15de821439011df1bb0bbd7682d674bd725d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7B ABCC6 ZIC2 DLGAP3 TRANK1

4.95e-051371295c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_monocytic-intermediate_monocyte|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DOCK4 PAPSS2 S100A12 LZTS1 TNNT1

5.87e-0514212959b39c778cfaf457303010f1b1cae8c0cd8fe5d1d
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DLGAP3 TRANK1 MYO3B DNAH8 KCNT1

6.27e-051441295e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

RFTN2 PAPSS2 PTPRS SMPD3 KPNA2

6.91e-05147129587c24843cb0e87ad42e725d08423131a5d2d25a3
ToppCellLeuk-UTI-Lymphocyte-T_NK-CD8_TCM|Leuk-UTI / Disease, Lineage and Cell Type

DOCK3 ZNF157 RFTN2 ITK TRAT1

7.60e-0515012950a65f5e2f4e0b0e822b029e0222b28ba2db89e6d
ToppCell367C-Lymphocytic-ILC-ILC-3|367C / Donor, Lineage, Cell class and subclass (all cells)

ZNF845 ANKHD1 ITK TRAT1 SMPD3

8.35e-0515312959d64aadbb4bb28469af1d728457b431e21577429
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

SPTB CHAD ATRNL1 KCNT1 MYBPC2

8.88e-051551295d7e26696fd9c0a759524f331243db43059b33ed9
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

B3GALT2 ZNF587B TRAT1 TRMT13 ARAP2

1.03e-0416012958e2b51d7b42e0b6e62641efdbbc73d31561d6a3e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF141 ZFP57 SLC25A12 IGFBP4 LZTS1

1.12e-0416312951c014e373667be290d7fb5d24c06c6f313ac8fa3
ToppCellURO-Lymphocyte-T_NK-MAIT|URO / Disease, Lineage and Cell Type

B3GALT2 FAM171B IGFBP4 TRAT1 MYO3B

1.16e-041641295cb42a70433b3968caca67f7aa98ea536cd90a0bc
ToppCell368C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DOCK3 LAD1 PPL PLEKHG1 ARAP2

1.16e-04164129567c636a2cc32e56c6186dc7e779cc19af04639d2
ToppCell368C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

DOCK3 LAD1 PPL PLEKHG1 ARAP2

1.19e-0416512959d2bdc42c13c8c2a68889bec8612a1ce56f659fa
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

KMT2E INTS3 INO80D PTPRF C19orf44

1.23e-04166129532d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell390C-Lymphocytic-ILC-ILC-2|390C / Donor, Lineage, Cell class and subclass (all cells)

ZNF587B TNRC18 SMPD3 OSGIN2 SOS1

1.30e-0416812952781dd6b369427a94c5059b44b4c8f023f5f2988
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITK PPP2R3A TRAT1 RRP12 KCNT1

1.33e-041691295a388e53deac861a185c31e9cceddae7bcb344700
ToppCell356C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

LAD1 PSD3 TIAM2 PLEKHG1 ARAP2

1.37e-041701295513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RBM39 ITK HERC1 KAT6B ARAP2

1.41e-0417112952e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell390C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZNF587B TNRC18 SMPD3 OSGIN2 SOS1

1.45e-04172129584d16cd7f618c94888920680bdc9e7130d73fd75
ToppCellnormal_Lung-T/NK_cells-Exhausted_Tfh|normal_Lung / Location, Cell class and cell subclass

DOCK3 NEK10 EZH2 TRAT1 KPNA2

1.49e-041731295e8ead6c51c41dbd43c717ba9d1a7a0ab39c79330
ToppCellBAL-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TRO PTPRS MED12L SMPD3 LRRC36

1.53e-041741295ab654e87c7eab7f33adc61be7a86da5c4d88008d
ToppCellBAL-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TRO PTPRS MED12L SMPD3 LRRC36

1.53e-041741295d9bccff5258c4277bdd1edbd87e17c327ec125e8
ToppCellBAL-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TRO PTPRS MED12L SMPD3 LRRC36

1.53e-0417412952453419842fd22d066631615403393bfe4449bb8
ToppCellBAL-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRO PTPRS MED12L SMPD3 LRRC36

1.57e-0417512956d5bdfbe53608e01c3845ecd908ca6d0fecc58f8
ToppCellBAL-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRO PTPRS MED12L SMPD3 LRRC36

1.57e-0417512956839ee3bb4457d13cb08ca8eb79ae33ddd256783
ToppCellBAL-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRO PTPRS MED12L SMPD3 LRRC36

1.57e-0417512959d6135e183179968555670abec39dff9da2c3219
ToppCellControl-Lymphoid-pDC|Control / Condition, Lineage and Cell class

TRO PTPRS MED12L SMPD3 LRRC36

1.61e-0417612955de16ff65476bde8b23322a44e11412e14f1bafe
ToppCellControl-Myeloid-pDC|Control / Disease group,lineage and cell class （2021.01.30）

TRO PTPRS MED12L SMPD3 LRRC36

1.61e-041761295baa3563973ea1a351fe028f55828463d2a51bf1a
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ZNF845 LAD1 ZNF696 PAPSS2 ZNF81

1.65e-041771295eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

SPTAN1 INO80D DST HERC1 KAT6B

1.65e-041771295e8ab340b20cd41554c3841fe980e078e878af35f
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 ASH1L BAZ1B RSRC2 ARAP2

1.70e-04178129501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-osteoclast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LAD1 RFTN2 PPL PPP2R3A RUFY4

1.70e-041781295a28683690ab8a60eb18f3ef87ea85da4e95b22df
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|343B / Donor, Lineage, Cell class and subclass (all cells)

NOL12 PSD3 INO80D ITK TRAT1

1.70e-0417812955289ac61637224ae70ffbc2d164d73116f10af40
ToppCellsevere-CD8+_T_naive|severe / disease stage, cell group and cell class

ZNF845 ZNF141 ANKZF1 PANK4 ZNF432

1.79e-04180129594fe530367b170777f4051a4034cff06d80dbb83
ToppCellsevere-CD8+_T_naive|World / disease stage, cell group and cell class

ZNF845 ZNF141 ANKZF1 PANK4 ZNF432

1.83e-04181129569eeeb7f326e230b07495d557f708fbe3312ac0a
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-8|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KCNH8 MYO7B PLEKHG1 IGFBP4 MYBPC2

1.83e-041811295ca34d83daca10c5fa52ecdf4eba7d31b4e7e056e
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

SPTAN1 ASH1L ITK HERC1 ARAP2

1.83e-041811295f2315414e714ac86211546a935660c4be6e85f1b
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SP100 ITK IGFBP4 TRAT1 USP3

1.88e-04182129501ae44b465e509b0aa75ccf61bd9bc0a89d6758c
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIAM2 TRANK1 LZTS1 SMPD3 KCNT1

1.88e-041821295d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPTAN1 ITK TRANK1 ZZZ3 TRAT1

1.88e-0418212951aea96ee211f7b9caef7fd385233f51be6021a73
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIAM2 TRANK1 LZTS1 SMPD3 KCNT1

1.88e-0418212956cde859edfe7607bd7ada89d20258413d06f4207
ToppCellnormal_Lung-Myeloid_cells-CD207+CD1a+_LCs|Myeloid_cells / Location, Cell class and cell subclass

TIAM2 PLEKHG1 SMPD3 RUFY4 MYBPC2

1.88e-0418212958dd79fef8f8463ad3194f9cc07c6cacf2c886304
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPTAN1 ITK TRANK1 ZZZ3 TRAT1

1.88e-041821295b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHBP1 PPL IGFBP4 TRAT1 MED12L

1.88e-0418212959174fb0b7ed8f721a5c513e41fd80476a9f34332
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPTAN1 ITK TRANK1 ZZZ3 TRAT1

1.88e-041821295c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPTAN1 ITK TRANK1 ZZZ3 TRAT1

1.88e-0418212954cb182ef39be2044a6ad7266f332d4177591e550
ToppCellSevere_COVID-19-B_cell-B_cell|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CHAD PLEKHG1 IGFBP4 DNAH8 RIC3

1.93e-0418312955634e528001c389efd1e380f01ad40072f60e943
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH8 ZFP57 RFTN2 PXK RNASE1

2.03e-041851295b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK4 SGK1 PLEKHG1 RNASE1 LRRC36

2.13e-041871295ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 PSD3 PPL DST MYO3B

2.13e-04187129587b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 PSD3 PPL DST MYO3B

2.13e-04187129542a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 PSD3 PPL DST MYO3B

2.13e-04187129564afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-8|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KCNH8 MYO7B PLEKHG1 IGFBP4 MYBPC2

2.13e-041871295c10d6a774b3e83f64e47b9ad08f5d6b0dc60d163
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNNM2 PTPRF TNNT1 C4orf33 KCNT1

2.13e-041871295f1e9877d859369b862d4a559ec9ab9be74a67a96
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNNM2 PTPRF TNNT1 C4orf33 KCNT1

2.13e-0418712953ffbd50b49059dcd3e23c5ac01901e4352142446
Drug2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A

MBTD1 CNNM2 SMG5 ANKZF1 XYLT2 PPP2R3A SUPT6H NIPBL ARAP2

1.90e-0619712996974_DN
DiseasePseudoxanthoma Elasticum, Incomplete

ABCC6 XYLT2

5.41e-0531262C1867450
DiseasePseudoxanthoma elasticum

ABCC6 XYLT2

5.41e-0531262cv:C0033847
DiseaseAutosomal recessive inherited pseudoxanthoma elasticum

ABCC6 XYLT2

5.41e-0531262cv:C1275116
DiseasePSEUDOXANTHOMA ELASTICUM

ABCC6 XYLT2

5.41e-0531262264800
DiseaseGronblad-Strandberg Syndrome

ABCC6 XYLT2

5.41e-0531262C0376359
DiseaseMetastatic melanoma

NEK10 GRK7 ITK MTOR

8.50e-05541264C0278883
DiseasePseudoxanthoma Elasticum

ABCC6 XYLT2

1.08e-0441262C0033847
Diseaseschizophrenia (implicated_via_orthology)

SETD1A CNNM2 ZIC2 MTOR

2.09e-04681264DOID:5419 (implicated_via_orthology)
Diseasehepatitis A virus cellular receptor 2 measurement

ABCC6 ITK

4.98e-0481262EFO_0008151
Diseasepseudoxanthoma elasticum (is_implicated_in)

ABCC6 XYLT2

6.39e-0491262DOID:2738 (is_implicated_in)
DiseaseAlzheimer disease, polygenic risk score

DOCK3 PDE8A PSD3 RNASE1 PPP2R3A DST LZTS1 USP3 HSPA6

9.52e-045861269EFO_0030082, MONDO_0004975
Disease1-methylurate measurement

PSD3 PTPRF

1.59e-03141262EFO_0021173
Diseasedaytime rest measurement

KCNH8 SPTB INO80D ITK LZTS1 USP3

1.72e-032951266EFO_0007828
Diseaseamyotrophic lateral sclerosis, age at onset

PTPRF ARAP2

1.83e-03151262EFO_0004847, MONDO_0004976
Diseaseprotein C measurement

MYO7B BAZ1B

2.36e-03171262EFO_0004633
Diseaselow affinity immunoglobulin gamma Fc region receptor II-a measurement

HSPA6 HSPA7

2.36e-03171262EFO_0021969
DiseaseColorectal Carcinoma

PQBP1 ABCC6 ZZZ3 PTPRS PANK4 ZNF432 CAMSAP2 DNAH8 RIC3

3.24e-037021269C0009402
Diseasevitamin D measurement

EHBP1 ASH1L KMT2E ZNF587B ZNF808 USP3

3.27e-033361266EFO_0004631
DiseaseRetinitis pigmentosa

PRPF8 PRPF3 FAM161A

3.95e-03741263cv:C0035334

Protein segments in the cluster

PeptideGeneStartEntry
SDRAEKFCGQKKRRH

ASH1L

1211

Q9NR48
KFNSFAIHGSKDKRS

C4orf33

131

Q8N1A6
RLKKKDREVSHAGAS

ARID4A

1216

P29374
IRKHKAAAEKAFQEG

BAZ1B

876

Q9UIG0
FKKDARSFKLRAGKH

ARAP2

1166

Q8WZ64
HKKSDGRRDKQISAS

DSCR4

101

P56555
KFKGQHIRDTDAFRS

CHAD

331

O15335
LNKDSQLGFHRSRKD

RCC1L

136

Q96I51
KLSSANGHEERSKKR

RBM39

21

Q14498
LTGFHKRKVERKKAA

NOL12

31

Q9UGY1
RHIKGEDKNKATSRS

RFTN2

416

Q52LD8
EDLNSKGKKREFRFH

INTS3

541

Q68E01
SKAFSQKRGLDEHKR

PRDM5

551

Q9NQX1
AKSKAHFFGKRDIRS

KAT6B

581

Q8WYB5
AKDRENARKIHESAG

PAPSS2

126

O95340
SLENHRIKSFKNKGR

KPNA3

6

O00505
KRHLFEKELAGQSRA

LAD1

441

O00515
QHLGSSSKKERDRQK

MED12L

1441

Q86YW9
RKSSHLKKLNRYSDG

LZTS1

26

Q9Y250
SIGHRFKRSDITKKQ

MBTD1

346

Q05BQ5
FKRSDITKKQDGHFD

MBTD1

351

Q05BQ5
GRSLDDARKRAKQFH

DST

6696

Q03001
EKKDFRAALRKQHAA

HERC1

1886

Q15751
EEKRKKRAFSGQGLH

KCNT1

621

Q5JUK3
NSFSDKGEERHKEKR

DYNC2I1

246

Q8WVS4
TKNDRSTEGKAHREK

CPSF1

51

Q10570
DATRKGNKIRFANHS

EZH2

676

Q15910
KRRKGSFGSIDHLQK

KIF27

906

Q86VH2
AFGKDKKDRDSSVRN

NEK10

556

Q6ZWH5
REGERKAAKLHFSQL

LRRC36

136

Q1X8D7
HSLKTQSLEGKRKAF

OR4A15

251

Q8NGL6
HDRKSGKKFSIEEAL

PPL

1711

O60437
DNQTGKHKDRRKGSL

PDE8A

346

O60658
HQNTGKLLKKEERSF

DNAH8

946

Q96JB1
SKTDKLERKHRHESG

NIPBL

861

Q6KC79
QHISKCKKAFREGSR

KMT2E

236

Q8IZD2
RFQRSHLAEAFAKAK

RIC3

66

Q7Z5B4
GKAFREKDKLDQHLR

PRDM10

536

Q9NQV6
TCGKQFKRKDKLREH

PRDM10

676

Q9NQV6
LKIQSREGRKKAFHT

OR2F1

226

Q13607
LKIQSREGRKKAFHT

OR2F2

226

O95006
FDKRAATKLKEQLHG

SMPD3

366

Q9NY59
NHAAYRKGRKVKSDS

PPP2R3A

136

Q06190
EFRRKHGKDLSGNKR

HSPA7

246

P48741
LHKNGSSEKREVRQF

PTPRS

1536

Q13332
KRHRDFLTNDAKFKE

PPP4R3C

236

Q6ZMV5
KTKKFDELLHLASRG

PANK4

231

Q9NVE7
AARLHRFKNKGKDST

KPNA2

11

P52292
KSDRSHEKLDRGHDK

PQBP1

116

O60828
ATRQKKKHLFVERGG

OSGIN2

486

Q9Y236
ANAAKEKAGRYRHRK

B3GALT2

406

O43825
ADKHNLFGKNLKERT

GSTA4

76

O15217
GRGSHRAKNKSKETF

CCPG1

471

Q9ULG6
FRHRSSLESKDKGEK

DOCK2

511

Q92608
RFEFRHCSTKDKGEK

DOCK3

506

Q8IZD9
RFEFRHCSTKEKGEK

DOCK4

486

Q8N1I0
RNKKEKSRDQEAGAH

ANKZF1

441

Q9H8Y5
RQAAKAEAKHEGARK

CROCC2

1186

H7BZ55
GHSRFLKRNQTLDEK

C19orf44

46

Q9H6X5
RSKSKDRKGDGRHQA

DLGAP3

241

O95886
IKKSRELNTRFSHGK

GPALPP1

321

Q8IXQ4
SDSKDKTSGVRNRKH

ATRNL1

1356

Q5VV63
KRLQRVGKHASKFQF

EHBP1

6

Q8NDI1
DHKRGHTKVKELARF

MCF2L

841

O15068
AESRQKKCRHTFRKA

INO80D

391

Q53TQ3
EFRRKHGKDLSGNKR

HSPA6

246

P17066
DTGFHAAEKRRKKRK

FAM161A

216

Q3B820
SREKSDDPRKHHFFK

GRK7

441

Q8WTQ7
AEQKFRKLNHTDGKS

CAMSAP2

701

Q08AD1
RHSFIDLKKGKRTQS

FAM171B

686

Q6P995
QRQRRTFKFHDKGKF

PRPF3

321

O43395
HKSGSSEKRELRQFQ

PTPRF

1496

P10586
FEDRHGKKRTLKGSI

ITK

41

Q08881
RDEKKKLRHASGANI

MTOR

1811

P42345
KDRVSDFHKLKQSRF

GOLM2

346

Q6P4E1
ENGEDRHKRKERKSS

RSRC2

106

Q7L4I2
RFKVDGKHRKKNSVF

TRMT13

221

Q9NUP7
NRISHAQKFRKGAGK

TNNT1

256

P13805
VGKSFERHKLKRQDA

SMG5

926

Q9UPR3
RKGHFDTLSKGELKQ

S100A12

21

P80511
LVGTIGKKFARKRDH

MPHOSPH6

121

Q99547
SAARRHNKAIAFKRK

ABCC6

261

O95255
KGSFGKVLLARHKAE

SGK1

106

O00141
PFFLEKKGESSRKHR

RUFY4

246

Q6ZNE9
KHFAKIRDRSTSGGK

IGFBP4

141

P22692
HGKELINFSKRRKVA

SOS1

951

Q07889
SLGKESRAKKFQRQH

RNASE1

26

P07998
EERGKTQGKHRKSFA

SETD1A

946

O15047
SFKKQERRGDHLRKA

OSBPL2

316

Q9H1P3
KKDHGFKVSADGRLI

RRP12

1141

Q5JTH9
ARDAKIEHRDKKGFT

ANKHD1

1076

Q8IWZ3
HARQAFALKDKSKSG

SLC25A12

161

O75746
KVAHRERKQDFSAFK

CNNM2

596

Q9H8M5
DKAFSFKSNLERHRK

ZNF845

361

Q96IR2
TTKERKKSRFGNAFH

PRPF8

531

Q6P2Q9
DVGHKKRKRTSFDDR

SUPT6H

81

Q7KZ85
LSLKSSREGKHKRAA

TNRC18

1686

O15417
KAFHEKTGFVRRKRT

ZNF157

141

P51786
GKAFSRKENLITHQK

ZNF568

256

Q3ZCX4
GKSFRDQSELKRHQK

ZFP57

181

Q9NU63
SLFAKKHGKEDTLRL

TIAM2

621

Q8IVF5
RGKRNRKSKHLNGDE

TRO

406

Q12816
KKIARALFNHIDKSG

RPAP3

636

Q9H6T3
KRADQRKAKLGDSHD

SPTAN1

1326

Q13813
DKDKSGRLNHQEFKS

SPTAN1

2336

Q13813
ENNSTLEKHSGKRRK

SP100

521

P23497
KAFGQRSDAAKHRRT

ZNF696

216

Q9H7X3
RFRTDDTINKKGFHA

TLL2

986

Q9Y6L7
DKVFGQKSALESHKR

ZNF808

601

Q8N4W9
AQSHHGSEEERKKRK

PXK

446

Q7Z7A4
RRKPRKQNTHFSDKD

TRAT1

121

Q6PIZ9
GATRALGKKHKDFLE

SPTB

776

P11277
HRLSLKKSFGFGKRD

UNQ9370/PRO34162

141

Q6UXP9
NKRKTRHTGEKHFKE

ZNF141

161

Q15928
GKAFRRSTDRSQHKK

ZNF141

401

Q15928
GKAFNRSSKLTEHKN

ZNF675

346

Q8TD23
GKAFSNRKDLIRHFS

ZNF264

461

O43296
VDHKDRKEFKTSLGN

ZNF587B

381

E7ETH6
LENSAFTADRHKKRK

USP3

121

Q9Y6I4
GKAFVKKSQLTDHER

ZNF432

211

O94892
GKKFVRKAILSDHQR

ZNF510

606

Q9Y2H8
RFAHKLKQTIKNGDS

TASOR2

1981

Q5VWN6
HNRRRKSDSKFVDAD

PLEKHG1

1296

Q9ULL1
NFNLKNKEGKDARHR

TRANK1

576

O15050
THSLGNFEREFKNRK

ZZZ3

571

Q8IYH5
DRFKRSDVAKHLGKN

PSD3

596

Q9NYI0
SSETFQKRNRIKHKG

WFDC13

71

Q8IUB5
SKNRDKNFLKSHGRD

XYLT2

346

Q9H1B5
KNFLKSHGRDNSRFI

XYLT2

351

Q9H1B5
KRDSFGKSFKHNLDL

ZNF81

191

P51508
GKVFARSENLKIHKR

ZIC2

341

O95409
KEDKVKGRSRAGTHF

KCNH8

146

Q96L42
KFKKISNRRNESAAH

MYO3B

1106

Q8WXR4
KAGNHLFKSADSNKR

MYO7B

611

Q6PIF6
RFKKDGKRHILIFSD

MYBPC2

396

Q14324