Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR1M1 ADORA3 TAS2R1 OR5J2 OR12D1 OR10G3 SIGMAR1 MLNR OR9G4 GPR149 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 FFAR4 OR51H1 OR8U8 OR11H6 OR51F1

1.23e-178846525GO:0004930
GeneOntologyMolecularFunctionolfactory receptor activity

OR1M1 OR5J2 OR12D1 OR10G3 OR9G4 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 OR51H1 OR8U8 OR11H6 OR51F1

7.46e-174316519GO:0004984
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR1M1 ADORA3 TAS2R1 OR5J2 OR12D1 OR10G3 SIGMAR1 MLNR OR9G4 GPR149 OR6J1 EVI2A OR10H4 OR6Y1 OR4D11 OR10C1 CHRNA10 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 FFAR4 OR51H1 OR8U8 GABRA3 OR11H6 OR51F1

2.41e-1613536528GO:0004888
GeneOntologyMolecularFunctionodorant binding

OR5J2 OR12D1 OR9G4 OR8D4 OR5F1 OR8U8

3.57e-06127656GO:0005549
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLCO1B7 SLC36A4 TMC6 CYB561D1 SLC38A5 SLC45A2 SLC5A12 CHRNA10 ATP2A1 SLC7A14 SLC38A6 ABCC10 RYR3 SLC35A5 GABRA3

4.34e-0611806515GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLCO1B7 SLC36A4 TMC6 CYB561D1 SLC38A5 SLC45A2 SLC5A12 CHRNA10 ATP2A1 SLC7A14 SLC38A6 ABCC10 RYR3 SLC35A5 GABRA3

1.26e-0512896515GO:0005215
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLCO1B7 SLC36A4 CYB561D1 SLC38A5 SLC45A2 SLC5A12 ATP2A1 ABCC10 SLC35A5

2.29e-05477659GO:0022804
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLCO1B7 SLC36A4 SLC38A5 SLC5A12 SLC7A14 SLC38A6

5.73e-05207656GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLCO1B7 SLC36A4 SLC38A5 SLC5A12 SLC7A14 SLC38A6

5.89e-05208656GO:0005342
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC36A4 SLC38A5 SLC38A6

3.21e-0441653GO:0015175
GeneOntologyMolecularFunctionL-glutamine transmembrane transporter activity

SLC38A5 SLC38A6

3.70e-049652GO:0015186
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLCO1B7 SLC36A4 SLC38A5 SLC5A12 SLC7A14 SLC38A6

3.79e-04293656GO:0008514
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC36A4 SLC38A5 SLC7A14 SLC38A6

3.82e-04105654GO:0015171
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLCO1B7 SLC36A4 SLC38A5 SLC45A2 SLC5A12 SLC35A5

4.00e-04296656GO:0015291
GeneOntologyMolecularFunctionaromatic amino acid transmembrane transporter activity

SLC36A4 SLC38A5

7.95e-0413652GO:0015173
GeneOntologyMolecularFunctionnucleotide-sugar transmembrane transporter activity

ATP2A1 SLC35A5

9.26e-0414652GO:0005338
GeneOntologyMolecularFunctionalanine transmembrane transporter activity

SLC36A4 SLC38A5

1.22e-0316652GO:0022858
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC36A4 SLC38A5 SLC38A6

1.61e-0371653GO:0015179
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC36A4 SLC38A5 SLC38A6

2.51e-0383653GO:0015101
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC38A5 SLC45A2 SLC5A12 CHRNA10 ATP2A1 ABCC10 RYR3 GABRA3

3.10e-03758658GO:0015318
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLCO1B7 SLC5A12 SLC7A14

3.16e-0390653GO:0008028
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR1M1 TAS2R1 OR5J2 IGF1 OR12D1 OR10G3 OR9G4 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 CHRNA10 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 FFAR4 OR51H1 OR8U8 OR11H6 OR51F1

7.47e-205826423GO:0050906
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR1M1 TAS2R1 OR5J2 IGF1 OR12D1 OR10G3 OR9G4 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 FFAR4 OR51H1 OR8U8 OR11H6 OR51F1

3.91e-195476422GO:0007606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR1M1 TAS2R1 OR5J2 OR12D1 OR10G3 OR9G4 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 FFAR4 OR51H1 OR8U8 OR11H6 OR51F1

6.60e-194856421GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR1M1 TAS2R1 OR5J2 OR12D1 OR10G3 OR9G4 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 FFAR4 OR51H1 OR8U8 OR11H6 OR51F1

3.20e-185246421GO:0009593
GeneOntologyBiologicalProcesssensory perception of smell

OR1M1 OR5J2 IGF1 OR12D1 OR10G3 OR9G4 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 OR51H1 OR8U8 OR11H6 OR51F1

6.03e-184656420GO:0007608
GeneOntologyBiologicalProcessdetection of stimulus

OR1M1 TAS2R1 OR5J2 IGF1 OR12D1 OR10G3 OR9G4 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 CHRNA10 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 FFAR4 OR51H1 OR8U8 OR11H6 OR51F1

8.80e-187226423GO:0051606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR1M1 OR5J2 OR12D1 OR10G3 OR9G4 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 OR51H1 OR8U8 OR11H6 OR51F1

3.12e-174326419GO:0050911
GeneOntologyBiologicalProcesssensory perception

OR1M1 TAS2R1 OR5J2 IGF1 OR12D1 OR10G3 ELFN1 OR9G4 OR6J1 OR10H4 OR6Y1 SLC45A2 OR4D11 OR10C1 CHRNA10 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 FFAR4 OR51H1 OR8U8 OR11H6 OR51F1

3.42e-1610726425GO:0007600
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR1M1 ADORA3 TAS2R1 OR5J2 OR12D1 OR10G3 SIGMAR1 MLNR OR9G4 GPR149 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 GNB2 OR4D5 OR8D4 OR52B2 ADCY5 OR51B2 OR5F1 FFAR4 OR51H1 OR8U8 OR11H6 OR51F1

1.50e-1513956427GO:0007186
GeneOntologyBiologicalProcesscarboxylic acid transport

SLCO1B7 SLC36A4 SLC38A5 SLC5A12 SLC7A14 SLC38A6 ABCC10

2.73e-04410647GO:0046942
GeneOntologyBiologicalProcesscarbohydrate transport

IGF1 SLC45A2 RTN2 FFAR4 SLC35A5

2.80e-04186645GO:0008643
GeneOntologyBiologicalProcessorganic acid transport

SLCO1B7 SLC36A4 SLC38A5 SLC5A12 SLC7A14 SLC38A6 ABCC10

2.81e-04412647GO:0015849
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

ATP2A1 RTN2 RYR3

3.71e-0445653GO:0033017
GeneOntologyCellularComponentpostsynaptic specialization membrane

SIGMAR1 ELFN1 CHRNA10 ELFN2 GABRA3

4.05e-04201655GO:0099634
MousePhenohyperactivity

SIGMAR1 ELFN1 AACS DNAH2 SLC45A2 GNB2 DDB1 ELFN2 AP3D1 NPAS4 RYR3 GABRA3

2.92e-0511723712MP:0001399
Domain7tm_1

OR1M1 ADORA3 OR5J2 OR10G3 MLNR OR9G4 GPR149 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 FFAR4 OR8U8 OR11H6

1.80e-146776120PF00001
DomainG_PROTEIN_RECEP_F1_1

OR1M1 ADORA3 OR5J2 OR10G3 MLNR OR9G4 GPR149 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 FFAR4 OR8U8 OR11H6

2.24e-146856120PS00237
DomainG_PROTEIN_RECEP_F1_2

OR1M1 ADORA3 OR5J2 OR10G3 MLNR OR9G4 GPR149 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 FFAR4 OR8U8 OR11H6

2.64e-146916120PS50262
DomainGPCR_Rhodpsn

OR1M1 ADORA3 OR5J2 OR10G3 MLNR OR9G4 GPR149 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 FFAR4 OR8U8 OR11H6

2.72e-146926120IPR000276
DomainOlfact_rcpt

OR1M1 OR5J2 OR10G3 OR9G4 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 OR8U8 OR11H6

9.33e-143936116IPR000725
DomainGPCR_Rhodpsn_7TM

OR1M1 ADORA3 OR5J2 OR10G3 MLNR OR9G4 GPR149 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 FFAR4 OR8U8 OR11H6

1.95e-136706119IPR017452
DomainAa_trans

SLC36A4 SLC38A5 SLC38A6

2.18e-0517613PF01490
DomainAA_transpt_TM

SLC36A4 SLC38A5 SLC38A6

2.18e-0517613IPR013057
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR1M1 OR5J2 OR10G3 OR9G4 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 OR51H1 OR8U8 OR11H6 OR51F1

1.10e-144175518M4072
PathwayREACTOME_SENSORY_PERCEPTION

OR1M1 TAS2R1 OR5J2 OR10G3 OR9G4 OR6J1 OR10H4 OR6Y1 OR4D11 OR10C1 CHRNA10 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 OR51H1 OR8U8 OR11H6 OR51F1

1.04e-136365520M41834
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR1M1 OR5J2 OR10G3 OR9G4 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR5F1 OR8U8 OR11H6 OR51F1

9.27e-133895516M14091
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR1M1 OR5J2 OR12D1 OR10G3 OR9G4 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR51H1 OR11H6 OR51F1

2.05e-18340651611875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR1M1 OR5J2 OR12D1 OR10G3 OR9G4 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR51H1 OR11H6 OR51F1

2.05e-18340651611802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR1M1 OR5J2 OR12D1 OR10G3 OR9G4 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR51H1 OR11H6 OR51F1

2.36e-18343651632295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR1M1 OR5J2 OR12D1 OR10G3 OR9G4 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR51B2 OR51H1 OR11H6 OR51F1

2.71e-18346651614611657
Pubmed

The human olfactory receptor gene family.

OR1M1 OR5J2 OR10G3 OR9G4 OR10H4 OR6Y1 OR4D11 OR10C1 OR4D5 OR8D4 OR52B2 OR5F1 OR51H1 OR11H6 OR51F1

6.33e-14541651514983052
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR1M1 OR10G3 OR9G4 OR10H4 OR4D11 OR10C1 OR52B2 OR51B2 OR5F1

3.11e-1021965912213199
Pubmed

Personal receptor repertoires: olfaction as a model.

OR12D1 OR10C1 OR51B2 OR51F1

7.82e-073865422908908
Pubmed

Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects.

SLC36A4 SLC38A5 SLC38A6

2.79e-061565323506890
Pubmed

The extracellular leucine-rich repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns.

ELFN1 ELFN2

3.44e-06265217868438
Pubmed

The evolutionary history and tissue mapping of amino acid transporters belonging to solute carrier families SLC32, SLC36, and SLC38.

SLC38A5 SLC38A6

1.03e-05365218418736
Pubmed

Complex N-glycosylation of mGluR6 is required for trans-synaptic interaction with ELFN adhesion proteins.

ELFN1 ELFN2

1.03e-05365238428819
Pubmed

Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.

ATP2A1 RYR3

2.06e-0546529384575
Pubmed

Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.

SIGMAR1 RYR3

3.43e-05565233060591
Pubmed

The human immunodeficiency virus type 1 Vpr protein upregulates PVR via activation of the ATR-mediated DNA damage response pathway.

ATR DDB1

3.43e-05565224045107
Pubmed

Inceptor counteracts insulin signalling in β-cells to control glycaemia.

IGF1 SLC38A5 FFAR4

3.58e-053465333505018
Pubmed

A probabilistic classifier for olfactory receptor pseudogenes.

OR10C1 OR51B2 OR51F1

3.91e-053565316939646
Pubmed

Type 3 and type 1 ryanodine receptors are localized in triads of the same mammalian skeletal muscle fibers.

ATP2A1 RYR3

5.13e-05665210444070
Pubmed

HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell-mediated killing.

ATR DDB1

7.18e-05765220008788
Pubmed

HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response.

ATR DDB1

7.18e-05765219798433
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

ATP2A1 RYR3

9.56e-05865219033399
Pubmed

Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.

ATP2A1 RYR3

9.56e-05865211784029
Pubmed

Vpr-induced DNA double-strand breaks: molecular mechanism and biological relevance.

ATR DDB1

1.23e-04965219275579
Pubmed

Interplay between cell-adhesion molecules governs synaptic wiring of cone photoreceptors.

ELFN1 ELFN2

1.53e-041065232879010
Pubmed

HIV-1 Vpr: mechanisms of G2 arrest and apoptosis.

ATR DDB1

1.53e-041065218514189
Pubmed

The functions of the HIV1 protein Vpr and its action through the DCAF1.DDB1.Cullin4 ubiquitin ligase.

ATR DDB1

1.53e-041065220347598
Pubmed

A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation.

GNB2 DDB1

1.87e-041165225982117
Pubmed

Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer.

IGF1 XRCC2 PGGT1B

2.18e-046265320403997
Pubmed

HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis.

ATR XRCC2

2.24e-041265224005329
Pubmed

Conditional stimulation of type V and VI adenylyl cyclases by G protein betagamma subunits.

GNB2 ADCY5

2.24e-041265217110384
Pubmed

Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people.

IGF1 ADCY5

2.24e-041265220419449
Pubmed

Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk.

ATR XRCC2

2.65e-041365219064565
Pubmed

Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling.

NPHP3 DDB1

2.65e-041365222863007
Pubmed

Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex.

OR12D1 OR10C1

2.65e-041365214506126
Pubmed

Pot1a prevents telomere dysfunction and ATM-dependent neuronal loss.

ATR XRCC2

3.08e-041465224899707
Pubmed

Platelet storage pool deficiency associated with inherited abnormalities of the inner ear in the mouse pigment mutants muted and mocha.

SLC45A2 AP3D1

3.08e-04146521912584
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR12D1 OR10G3 OR6Y1

3.67e-047465315081110
Pubmed

HIV-1 Vpr-a still "enigmatic multitasker".

ATR DDB1

4.06e-041665224744753
Pubmed

Structure-function relationship of Vpr: biological implications.

ATR DDB1

4.06e-041665219275588
Pubmed

Docking motif-guided mapping of the interactome of protein phosphatase-1.

ELFN1 ELFN2 SLC7A14

4.62e-048065319389623
Pubmed

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

IGF1 ADCY5

6.39e-042065220081858
Pubmed

Polymorphisms of DNA repair genes and risk of non-small cell lung cancer.

ATR XRCC2

6.39e-042065216195237
Pubmed

HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells.

IGF1 BCL6

7.76e-042265211994280
Pubmed

Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human.

EVI2A GNB2

9.24e-04246522902634
Pubmed

Vpr and its interactions with cellular proteins.

ATR DDB1

1.26e-032865220012529
Pubmed

Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.

IGF1 ATR XRCC2

1.39e-0311765319124506
Pubmed

SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.

TMEM267 TMC6 ATP2A1 ELFN2 PGGT1B RYR3 SLC35A5

1.58e-0391565732393512
Pubmed

Integral and associated lysosomal membrane proteins.

GNB2 AP3D1 ABCC10

1.72e-0312665317897319
Pubmed

Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse.

OR52B2 OR51F1

1.75e-033365217350283
CytobandEnsembl 112 genes in cytogenetic band chr11q12

OR5J2 OR9G4 OR4D11 DDB1 OR5F1

1.33e-04345655chr11q12
CytobandEnsembl 112 genes in cytogenetic band chr11p15

CHRNA10 OR52B2 OR51B2 OR51H1 OR51F1

1.24e-03564655chr11p15
Cytoband11q24.1

OR4D5 OR8D4

1.27e-033765211q24.1
Cytoband11q12.1

OR9G4 OR4D11 OR5F1

1.58e-0316165311q12.1
Cytoband11q11

OR5J2 OR8U8

2.05e-034765211q11
Cytoband14q11.2

OR10G3 OR6J1 OR11H6

2.17e-0318065314q11.2
Cytoband11p15.4

OR52B2 OR51H1 OR51F1

2.92e-0320065311p15.4
GeneFamilySolute carriers

SLCO1B7 SLC36A4 SLC38A5 SLC45A2 SLC5A12 SLC7A14 SLC38A6 SLC35A5

2.40e-05395558752
GeneFamilyOlfactory receptors, family 51

OR51B2 OR51H1 OR51F1

3.23e-0444553164
GeneFamilyOlfactory receptors, family 10

OR10G3 OR10H4 OR10C1

1.06e-0366553157
ToppCelldroplet-Spleen-nan-3m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA3 ATP2A1 RYR3 FFAR4

9.56e-05166644c1f18de4a1a2b6cdc703e6d29d136e1134fcbdf3
ToppCelldroplet-Spleen-nan-3m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA3 ATP2A1 RYR3 FFAR4

9.56e-0516664494c30d6ca179d0cb02a5ed0093c5a2871e17ae50
ToppCell10x5'-bone_marrow-Lymphocytic_B_plasma-Plasma_cells|bone_marrow / Manually curated celltypes from each tissue

DPEP1 IGF1 SLC38A5 HM13

1.12e-04173644300904fd35536a69be81d76fe33fe16544523ceb
ToppCell10x5'-bone_marrow-Lymphocytic_B_plasma|bone_marrow / Manually curated celltypes from each tissue

DPEP1 IGF1 SLC38A5 HM13

1.15e-04174644b1931028cf80af5eff6da15d7f0196205f17926f
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADORA3 SIGMAR1 XRCC2 FFAR4

1.15e-0417464409b091e24317c3f7bac043f04762a533e30793de
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ELFN1 ADCY5 ABCC10 GABRA3

1.22e-0417764430f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IGF1 ELFN1 GPR149 BCL6

1.25e-041786443c973aac16988e88f5677d3d695dd772ccfd6570
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ELFN1 GPR149 BCL6 RYR3

1.25e-041786442a36475c260088f69f3b8c282d910e5eaa5c5c2d
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells|lymph-node_spleen / Manually curated celltypes from each tissue

DPEP1 IGF1 SLC38A5 HM13

1.39e-04183644a6866951866373a1029e04818f4a4a31278c409d
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B_plasma|lymph-node_spleen / Manually curated celltypes from each tissue

DPEP1 IGF1 SLC38A5 HM13

1.39e-04183644beadc69f511cf183e493cb445135f0748ab8b20e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ELFN1 GPR149 BCL6 RYR3

1.45e-041856440b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCellmetastatic_Lymph_Node-B_lymphocytes-MALT_B_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

DPEP1 IGF1 SLC38A5 HM13

1.45e-04185644bb87fa174f80706fe7be60d3b9fc3e2a6b373038
ToppCellLAM-Lymphoid-B-cell-2|Lymphoid / Condition, Lineage and Cell class

DPEP1 IGF1 SLC38A5 HM13

1.48e-04186644bcfe0bf2f7f745146b74496a4fcfccd869ad7c6f
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGPP2 SLC7A14 RTN2 NPAS4

1.48e-04186644f5468e03321ea2083e223eb0d92c3a9307039569
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DPEP1 IGF1 SLC38A5 RTN2

1.48e-0418664488e6246172d816806a498a5c1f38e699f2f5d7c2
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells|lymph-node_spleen / Manually curated celltypes from each tissue

DPEP1 IGF1 SLC38A5 HM13

1.54e-04188644c7b1807c96f87fbcd37739a159cf00f9a1ff5d71
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DPEP1 IGF1 SLC38A5 HM13

1.54e-04188644ecba5d06cbf3254448255a2aeefffe711f43310e
ToppCellnormal_Pleural_Fluid-B_lymphocytes-MALT_B_cells|normal_Pleural_Fluid / Location, Cell class and cell subclass

DPEP1 IGF1 SLC38A5 HM13

1.57e-0418964405e8fb483ebb9010cc54b39d78cca960c58c0f01
ToppCellnormal-na-Lymphocytic_B-B_plasma|normal / PBMC cell types (v2) per disease, treatment status, and sex

DPEP1 IGF1 SLC38A5 HM13

1.57e-04189644659deb617a560bcde67c75f477d30ce85aaec3c6
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_plasma-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DPEP1 IGF1 SLC38A5 HM13

1.57e-0418964459e6fec454de621119571d4a8ec48be3bf02a32e
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_plasma|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DPEP1 IGF1 SLC38A5 HM13

1.57e-0418964443f25fb7257eab05df921ffcd5a6e49c78a03e3a
ToppCellnormal-na-Lymphocytic_B-B_plasma-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

DPEP1 IGF1 SLC38A5 HM13

1.57e-0418964467f9a9861d2dcc128b7a69432c6b31da185e2249
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DPEP1 IGF1 SLC38A5 HM13

1.61e-0419064476b747bafff09bf8375a5717c9f213cbfb405bac
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

DPEP1 IGF1 SLC38A5 HM13

1.61e-04190644ce70336679a2b713836e7497e6dc48aac612b018
ToppCellfacs-Lung-EPCAM|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPEP1 SLC38A5 EVI2A FFAR4

1.64e-0419164400957dd6077e107722835084d769e84eace0611f
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DPEP1 IGF1 SLC38A5 HM13

1.64e-041916447b4b5d90d1023d03239ed986f273afa734d3124d
ToppCellnormal_Lymph_Node-B_lymphocytes-Plasma_cells|B_lymphocytes / Location, Cell class and cell subclass

DPEP1 IGF1 SLC38A5 HM13

1.67e-04192644119832d4aee29ddda2485fc3e5dcdaacf833cc30
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPEP1 IGF1 SLC38A5 RTN2

1.71e-04193644abdfb8b1dbdcb424042e21017a9e829fced4457e
ToppCell(5)_Plasma_IgG|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

DPEP1 IGF1 SLC38A5 HM13

1.71e-04193644a94ebb3bca62970d5d17b0234893918ee6b7b808
ToppCellB_cell_maturation-plasma|B_cell_maturation / Lineage and Cell class

DPEP1 IGF1 SLC38A5 HM13

1.71e-041936445415f7e54bc40aec3dbe27fd97f6e9be6db08a48
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPEP1 IGF1 SLC38A5 RTN2

1.71e-04193644027e098ad018e782287f84eee0f77551018f2196
ToppCellmetastatic_Brain-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

DPEP1 IGF1 SLC38A5 HM13

1.71e-04193644d05535eaabb6b4069b72b23d852888d4191407fd
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPEP1 IGF1 SLC38A5 RTN2

1.71e-04193644c5463a87f20b3a7f7ffda677b2f5a0e9e49d6685
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B_plasma|lymph-node_spleen / Manually curated celltypes from each tissue

DPEP1 IGF1 SLC38A5 HM13

1.74e-0419464442f43cac0dec704afd18143192e3ab68360ea076
ToppCellnormal_Lymph_Node-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

DPEP1 IGF1 SLC38A5 HM13

1.74e-041946441ca034f25a8fce503fb67654d7fa2a8ec71976be
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DPEP1 IGF1 SLC38A5 HM13

1.74e-04194644ffba703f61faaac8b4b9a5e46cd335214303de7b
ToppCelltumor_Lung-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

DPEP1 IGF1 SLC38A5 HM13

1.81e-041966441f63dba9d226e4a42d9bee7258580a1e547c0e92
ToppCell10x3'2.3-week_17-19-Myeloid_macrophage-stroma-stromal_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADORA3 IGF1 SLC38A6 GABRA3

1.81e-0419664488517bb92be2f05c1e1ad94af22ac10d8c5c13c7
ToppCellmLN-B_cell-B_cell_IgG_Plasma|B_cell / Region, Cell class and subclass

DPEP1 IGF1 SLC38A5 HM13

1.84e-04197644bd1d01d6c49f68f5c85d84df96c90dd04b9de09b
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DPEP1 IGF1 SLC38A5 HM13

1.84e-041976446fe013f98c64b3c5a4e61002254717fb411f8e59
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CBLN1-L2-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

OR9G4 GPR149 BCL6 RYR3

1.95e-042006442086024ce808b8796ed508a229b098eb02f8828a
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3|Neuronal / cells hierarchy compared to all cells using T-Statistic

IGF1 ELFN1 GPR149 BCL6

1.95e-042006447e51715525fdb001b7042b2bfcb9de81ecb5e4ee
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)|Neuronal / cells hierarchy compared to all cells using T-Statistic

IGF1 ELFN1 GPR149 BCL6

1.95e-0420064475649534a98bc738fca62d071de0978dc61eb24f
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CBLN1|Neuronal / cells hierarchy compared to all cells using T-Statistic

OR9G4 GPR149 BCL6 RYR3

1.95e-0420064435951db6a4f442ac9e13f1b8cc5b4a33481f92c8
Diseaseskin sensitivity to sun

DPEP1 SLC45A2

6.36e-0419582EFO_0004795
DiseaseChronic myeloproliferative disorder

IGF1 ATR

6.36e-0419582C1292778
Diseasenose morphology measurement, mouth morphology measurement

OR4D5 OR8D4

7.78e-0421582EFO_0007843, EFO_0007955
DiseaseSeckel syndrome

IGF1 ATR

8.55e-0422582C0265202
Diseasepancreatic cancer (is_implicated_in)

IGF1 ATR XRCC2

1.41e-03112583DOID:1793 (is_implicated_in)
Diseasebilirubin measurement

SLCO1B7 TMC6 SGPP2 OR6Y1 BCL6

1.76e-03442585EFO_0004570
Diseaseresponse to allopurinol, uric acid measurement

OR4D5 OR8D4

1.81e-0332582EFO_0004761, EFO_0006337

Protein segments in the cluster

PeptideGeneStartEntry
FSTALTILIMNLHYC

CHRNA10

311

Q9GZZ6
HLTCGLVVYLMATVT

CYB561D1

166

Q8N8Q1
SPSTATHYIMTILGC

ELFN1

411

P0C7U0
ITIHFYSCLFMTCLL

ADORA3

76

P0DMS8
LLHGNMTSSDILLCY

AACS

316

Q86V21
SIFMLSFYLTCSLLL

ADCY5

786

O95622
SICLSMSLHFLILYV

ATP2A1

936

O14983
LIHSTSAMSLLYECV

AP3D1

266

O14617
CSSHMLAVTIFYGTL

OR8U8

241

P0C7N1
TISYTSCMTQIFLFH

OR4D11

91

Q8NGI4
GMLSYTTRLLCTHRT

ABCC10

771

Q5T3U5
CSSHLTAVLMFYGSL

OR8D4

241

Q8NGM9
FSTCGSHLMVVSLFY

OR11H6

256

Q8NGC7
SIFFHLMTCVLSLGV

DOLK

256

Q9UPQ8
ALHFLVQSGISYCIM

MBOAT2

76

Q6ZWT7
CHLLFYVMTLSGSVT

FFAR4

111

Q5NUL3
SHISCVLIFYVTVMG

OR51B2

241

Q9Y5P1
ISLYSCIVQMFFLHG

OR51F1

101

A6NGY5
STCLSHMSTVLLFYV

OR51H1

241

Q8NH63
STCGSHLCVILMFYV

OR52B2

241

Q96RD2
YLHLAFLMTTVFSLS

EVI2A

11

P22794
LLMYSHDNIICGITS

GNB2

261

P62879
TSHCYMTSLGILFLI

GABRA3

6

P34903
SMYFFVLGILALSHT

HM13

106

Q8TCT9
HFLGSTQCFLYTLMA

OR10G3

106

Q8NGC4
ITSKLHTPMYFLLSC

OR5J2

51

Q8NH18
LHTPMYLFLCTLSVS

OR10H4

56

Q8NGA5
LSTCASHFMVVILLY

OR12D1

231

P0DN82
CASHLISVMLFYGSL

OR9G4

256

Q8NGQ1
CLMTFAALVGSIYSL

GPR149

41

Q86SP6
RLSYLHIMSLACIYT

NPAS4

36

Q8IUM7
CTLHGMFYLTSSLTE

ATR

716

Q13535
HKTVLMACSGLFYSI

BCL6

46

P41182
TMSSSHLFYLALCLL

IGF1

26

P05019
LTDRCYMTLTTALHL

DNAH2

1781

Q9P225
LYQLGMRYLTLTHSC

DPEP1

156

P16444
VLCSLFGVMSSTLYT

SLC45A2

426

Q9UMX9
ILMTTFESSHYLLCA

DDB1

591

Q16531
CTYATLLHMTALSVE

MLNR

121

O43193
VTLMCFLVLLGSYTA

OR4D5

206

Q8NGN0
SSHLIMVSLFYGTAL

OR10C1

241

Q96KK4
SLATTECILFGLMAY

OR5F1

106

O95221
FSCFISLTHILLMAR

OR1M1

151

Q8NGA1
VYRSHLMSSLLCLEG

MT-ND4L

21

P03901
HIAMTYTGLSCLVIL

PGGT1B

121

P53609
FTGLMVSLLCLLHFS

RTN2

361

O75298
SLIHSLYKMCLLTYG

NPHP3

801

Q7Z494
ICLHNVGAMSSYLFI

SLC38A5

131

Q8WUX1
YTSGLSLTCMLFFLV

SLC38A5

196

Q8WUX1
ALLASYSVHLLLSMC

SLC38A6

86

Q8IZM9
MAFSFLCHTSILPIY

SLC38A6

256

Q8IZM9
GAMCLLHASLSEYVL

SIGMAR1

91

Q99720
IFTLLHMSSYIASLT

SLCO1B7

296

G3V0H7
STVLSCSRLHTPMYF

OR6J1

46

Q8NGC5
CASHLTVVILFYSMT

OR6Y1

246

Q8NGX8
TLVCLSRLYTGMHTV

SGPP2

201

Q8IWX5
LGSLLYVSMICVFHS

TAS2R1

131

Q9NYW7
MSIGTLLAYTLVSVC

SLC7A14

411

Q8TBB6
ICSLSTMYTFLLGAI

SLC35A5

11

Q9BS91
LRHSFSGMYLTCLTT

RYR3

111

Q15413
GSMLVSSYILICSNH

NSD3

836

Q9BZ95
LLLTLYSLESMFCSH

XRCC2

126

O43543
FFITCITLVYSMAHS

TMC6

351

Q7Z403
SHMSTVFLTLLCFPA

TMC6

646

Q7Z403
TSVLLLIHLGCYFSS

UGT2B28

6

Q9BY64
ILVCAVFSGLIMYSH

SLC5A12

286

Q1EHB4
TLYVTLATLGYMCFH

SLC36A4

316

Q6YBV0
SSLPHICSFVMYLTG

TMEM267

186

Q0VDI3
TSTTTHYIMTILGCL

ELFN2

391

Q5R3F8