Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC26A9 ABCC9 SLC6A15 SLC30A3 NDUFS1 SLC22A7 SLC13A4 SLC15A1 ABCA5 SLC15A4 SLC25A2 SLC16A14 SLC28A2 SLC5A8 TAP1	3.77e-05	477	184	15	GO:0022804
GeneOntologyMolecularFunction	peptide transmembrane transporter activity	SLC15A1 SLC15A4 TAP1	6.21e-05	9	184	3	GO:1904680
GeneOntologyMolecularFunction	haptoglobin binding	HBG1 HBG2 HBZ	8.81e-05	10	184	3	GO:0031720
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC26A9 SLC6A15 SLC30A3 SLC22A7 SLC13A4 SLC15A1 SLC15A4 SLC25A2 SLC16A14 SLC28A2 SLC5A8	9.87e-05	296	184	11	GO:0015291
GeneOntologyMolecularFunction	GDP phosphatase activity	GBP1 GBP2 GBP3	1.59e-04	12	184	3	GO:0004382
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC26A9 ABCC9 SLC6A15 ANO5 PKD1L3 SLC30A3 NDUFS1 SLC13A4 CLCA1 SLC15A1 CLIC2 SLC15A4 SLC28A2 KCNMA1 SCNN1B CACNA1H SLC5A8 KCNH5	2.33e-04	758	184	18	GO:0015318
GeneOntologyMolecularFunction	dihydrofolic acid binding	DHFR DHFR2	2.52e-04	3	184	2	GO:0051871
GeneOntologyMolecularFunction	dihydrofolate reductase activity	DHFR DHFR2	2.52e-04	3	184	2	GO:0004146
GeneOntologyMolecularFunction	oxygen carrier activity	HBG1 HBG2 HBZ	2.60e-04	14	184	3	GO:0005344
GeneOntologyMolecularFunction	spectrin binding	GBP1 GBP2 GBP3 DYNC1I1	2.61e-04	34	184	4	GO:0030507
GeneOntologyMolecularFunction	transporter activity	SLC26A9 ABCC9 SLC6A15 ANO5 APOB PKD1L3 SLC30A3 NDUFS1 SLC22A7 SLC13A4 CLCA1 SLC15A1 ABCA5 CLIC2 SLC15A4 SLC25A2 SLC16A14 NPC1L1 SLC28A2 KCNMA1 SCNN1B CACNA1H SLC5A8 TAP1 KCNH5	3.36e-04	1289	184	25	GO:0005215
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	HYAL4 GANC CEMIP2 GBA3 NEU1 FUCA1	3.85e-04	103	184	6	GO:0004553
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC26A9 ABCC9 SLC6A15 ANO5 PKD1L3 SLC30A3 NDUFS1 SLC13A4 CLCA1 SLC15A1 CLIC2 SLC15A4 SLC28A2 KCNMA1 SCNN1B CACNA1H SLC5A8 KCNH5	4.01e-04	793	184	18	GO:0015075
GeneOntologyMolecularFunction	symporter activity	SLC6A15 SLC13A4 SLC15A1 SLC15A4 SLC16A14 SLC28A2 SLC5A8	4.89e-04	150	184	7	GO:0015293
GeneOntologyMolecularFunction	cytoskeletal protein-membrane anchor activity	EPB41L3 SYN1	5.01e-04	4	184	2	GO:0106006
GeneOntologyMolecularFunction	peptide:proton symporter activity	SLC15A1 SLC15A4	5.01e-04	4	184	2	GO:0015333
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC26A9 ABCC9 SLC6A15 ANO5 PKD1L3 SLC30A3 NDUFS1 SLC22A7 SLC13A4 CLCA1 SLC15A1 ABCA5 CLIC2 SLC15A4 SLC25A2 SLC16A14 SLC28A2 KCNMA1 SCNN1B CACNA1H SLC5A8 TAP1 KCNH5	5.52e-04	1180	184	23	GO:0022857
GeneOntologyMolecularFunction	nucleoside diphosphate phosphatase activity	GBP1 GBP2 GBP3	7.82e-04	20	184	3	GO:0017110
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC6A15 SLC13A4 SLC15A1 SLC15A4 SLC28A2 SLC5A8	8.28e-04	119	184	6	GO:0015294
GeneOntologyMolecularFunction	hemoglobin alpha binding	HBG1 HBG2	8.29e-04	5	184	2	GO:0031721
GeneOntologyMolecularFunction	dipeptide transmembrane transporter activity	SLC15A1 SLC15A4	8.29e-04	5	184	2	GO:0071916
GeneOntologyMolecularFunction	cell adhesion molecule binding	SPTBN1 SRC EIF3E CAPZB CEMIP2 TENM4 PTPRD PTPRH CD226 PKP1 MACF1 CTNND1 TNR CXADR	1.36e-03	599	184	14	GO:0050839
GeneOntologyMolecularFunction	endopeptidase inhibitor activity	SERPINE3 GBP1 GBP2 GBP3 MANSC4 C3 PZP	1.43e-03	180	184	7	GO:0004866
GeneOntologyMolecularFunction	connexin binding	SRC CXADR	1.72e-03	7	184	2	GO:0071253
GeneOntologyMolecularFunction	peptidase inhibitor activity	SERPINE3 GBP1 GBP2 GBP3 MANSC4 C3 PZP	1.77e-03	187	184	7	GO:0030414
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC26A9 ABCC9 SLC6A15 NDUFS1 SLC13A4 SLC15A1 SLC15A4 SLC28A2 SLC5A8	1.96e-03	301	184	9	GO:0022853
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	ABCC9 SLC6A15 PKD1L3 SLC30A3 NDUFS1 SLC13A4 SLC15A1 SLC15A4 SLC28A2 KCNMA1 SCNN1B CACNA1H SLC5A8 KCNH5	2.07e-03	627	184	14	GO:0022890
GeneOntologyMolecularFunction	hydrolase activity, acting on glycosyl bonds	HYAL4 GANC CEMIP2 GBA3 NEU1 FUCA1	2.20e-03	144	184	6	GO:0016798
GeneOntologyBiologicalProcess	positive regulation of AIM2 inflammasome complex assembly	GBP1 GBP2 GBP3	2.82e-06	4	185	3	GO:0140973
GeneOntologyBiologicalProcess	regulation of AIM2 inflammasome complex assembly	GBP1 GBP2 GBP3	1.39e-05	6	185	3	GO:0140971
GeneOntologyBiologicalProcess	AIM2 inflammasome complex assembly	GBP1 GBP2 GBP3	3.85e-05	8	185	3	GO:0140970
GeneOntologyBiologicalProcess	cytoplasmic pattern recognition receptor signaling pathway	LYPLAL1 SRC RNF135 GBP1 GBP2 GBP3 NOD1 SLC15A4 TLR3	5.19e-05	188	185	9	GO:0002753
GeneOntologyBiologicalProcess	positive regulation of pyroptotic inflammatory response	GBP1 GBP2 GBP3	5.73e-05	9	185	3	GO:0140639
GeneOntologyBiologicalProcess	cytolysis in another organism	GBP1 GBP2 GBP3	5.73e-05	9	185	3	GO:0051715
GeneOntologyCellularComponent	host cellular component	GBP1 GBP2 GBP3 KPNA2	7.84e-06	15	187	4	GO:0018995
GeneOntologyCellularComponent	host intracellular region	GBP1 GBP2 GBP3	1.38e-05	6	187	3	GO:0043656
GeneOntologyCellularComponent	host cell cytoplasm	GBP1 GBP2 GBP3	1.38e-05	6	187	3	GO:0030430
GeneOntologyCellularComponent	host cell part	GBP1 GBP2 GBP3	1.38e-05	6	187	3	GO:0033643
GeneOntologyCellularComponent	host intracellular part	GBP1 GBP2 GBP3	1.38e-05	6	187	3	GO:0033646
GeneOntologyCellularComponent	host cell cytoplasm part	GBP1 GBP2 GBP3	1.38e-05	6	187	3	GO:0033655
GeneOntologyCellularComponent	symbiont-containing vacuole	GBP1 GBP2 GBP3	1.38e-05	6	187	3	GO:0020003
GeneOntologyCellularComponent	symbiont-containing vacuole membrane	GBP1 GBP2 GBP3	1.38e-05	6	187	3	GO:0020005
GeneOntologyCellularComponent	symbiont cell surface	GBP1 GBP2 GBP3	3.82e-05	8	187	3	GO:0106139
GeneOntologyCellularComponent	other organism part	GBP1 GBP2 GBP3	5.69e-05	9	187	3	GO:0044217
GeneOntologyCellularComponent	haptoglobin-hemoglobin complex	HBG1 HBG2 HBZ	1.46e-04	12	187	3	GO:0031838
GeneOntologyCellularComponent	hemoglobin complex	HBG1 HBG2 HBZ	1.46e-04	12	187	3	GO:0005833
GeneOntologyCellularComponent	neuron to neuron synapse	SPTBN1 EIF3E CAPZB EPB41L3 SLC30A3 PTPRD SYN1 SYN2 MACF1 FLRT3 CTNND1 TNR EPHA4 KPNA2	2.71e-04	523	187	14	GO:0098984
GeneOntologyCellularComponent	hippocampal mossy fiber to CA3 synapse	CAPZB SLC30A3 PTPRD CTNND1 TNR	3.35e-04	67	187	5	GO:0098686
GeneOntologyCellularComponent	Schaffer collateral - CA1 synapse	CAPZB PTPRD SYN1 SYN2 CTNND1 TNR EPHA4	5.01e-04	155	187	7	GO:0098685
GeneOntologyCellularComponent	vesicle membrane	PLEKHB2 REP15 VPS33A GBP1 SLC26A9 GBP2 GBP3 APOB SLC30A3 SCARF1 SCAP CLCA1 ABCA5 SLC15A4 SNX25 NPC1L1 TLR3 SLC28A2 SCNN1B PKP1 SYN1 SYN2 TAP1 EPHA4	7.78e-04	1325	187	24	GO:0012506
Domain	ARM-type_fold	ZYG11A HEATR4 MROH5 APOB HUWE1 AP4E1 HEATR6 CEBPZ ELMO2 MROH2B PKP1 TAF2 CTNND1 NIPBL KPNA2	1.51e-06	339	185	15	IPR016024
Domain	-	ZYG11A HEATR4 MROH5 AP4E1 ARID1B HEATR6 ELMO2 MROH2B PKP1 CTNND1 NIPBL KPNA2	2.26e-06	222	185	12	1.25.10.10
Domain	ARM-like	ZYG11A HEATR4 MROH5 HUWE1 AP4E1 ARID1B HEATR6 ELMO2 MROH2B PKP1 CTNND1 NIPBL KPNA2	3.07e-06	270	185	13	IPR011989
Domain	WD40_repeat_dom	ITFG2 MED16 STXBP5L KATNB1 PAAF1 ARHGEF17 SCAP DAW1 WDR87 SMU1 WDR12 DYNC1I1	4.23e-05	297	185	12	IPR017986
Domain	DHFR_1	DHFR DHFR2	9.76e-05	2	185	2	PF00186
Domain	DHFR_1	DHFR DHFR2	9.76e-05	2	185	2	PS00075
Domain	DHFR_dom	DHFR DHFR2	9.76e-05	2	185	2	IPR001796
Domain	DHFR_2	DHFR DHFR2	9.76e-05	2	185	2	PS51330
Domain	-	DHFR DHFR2	9.76e-05	2	185	2	3.40.430.10
Domain	DHFR-like_dom	DHFR DHFR2	9.76e-05	2	185	2	IPR024072
Domain	DHFR	DHFR DHFR2	9.76e-05	2	185	2	IPR012259
Domain	GBP_C	GBP1 GBP2 GBP3	1.09e-04	10	185	3	PF02841
Domain	-	MED16 STXBP5L KATNB1 FSTL4 PAAF1 ARHGEF17 SCAP DAW1 WDR87 SMU1 WDR12 DYNC1I1	1.26e-04	333	185	12	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	MED16 STXBP5L KATNB1 FSTL4 PAAF1 ARHGEF17 SCAP DAW1 WDR87 SMU1 WDR12 DYNC1I1	1.33e-04	335	185	12	IPR015943
Domain	G_GB1_RHD3_dom	GBP1 GBP2 GBP3	1.49e-04	11	185	3	IPR030386
Domain	Guanylate-bd_N	GBP1 GBP2 GBP3	1.49e-04	11	185	3	IPR015894
Domain	Guanylate-bd_C	GBP1 GBP2 GBP3	1.49e-04	11	185	3	IPR003191
Domain	GBP	GBP1 GBP2 GBP3	1.49e-04	11	185	3	PF02263
Domain	G_GB1_RHD3	GBP1 GBP2 GBP3	1.49e-04	11	185	3	PS51715
Domain	Globin	HBG1 HBG2 HBZ	1.97e-04	12	185	3	IPR000971
Domain	Globin	HBG1 HBG2 HBZ	1.97e-04	12	185	3	PF00042
Domain	GLOBIN	HBG1 HBG2 HBZ	1.97e-04	12	185	3	PS01033
Domain	-	ACACA SYN1 SYN2	2.54e-04	13	185	3	3.40.50.20
Domain	-	HBG1 HBG2 HBZ	2.54e-04	13	185	3	1.10.490.10
Domain	Globin/Proto	HBG1 HBG2 HBZ	2.54e-04	13	185	3	IPR012292
Domain	WD40	MED16 STXBP5L KATNB1 PAAF1 SCAP DAW1 WDR87 SMU1 WDR12 DYNC1I1	2.67e-04	259	185	10	PF00400
Domain	Synapsin_pre-ATP-grasp_dom	SYN1 SYN2	2.91e-04	3	185	2	IPR020897
Domain	Synapsin_ATP-bd_dom	SYN1 SYN2	2.91e-04	3	185	2	IPR020898
Domain	SYNAPSIN_1	SYN1 SYN2	2.91e-04	3	185	2	PS00415
Domain	SYNAPSIN_2	SYN1 SYN2	2.91e-04	3	185	2	PS00416
Domain	Synapsin_C	SYN1 SYN2	2.91e-04	3	185	2	PF02750
Domain	Synapsin_N	SYN1 SYN2	2.91e-04	3	185	2	PF10581
Domain	PTR2_symporter_CS	SLC15A1 SLC15A4	2.91e-04	3	185	2	IPR018456
Domain	Synapsin_CS	SYN1 SYN2	2.91e-04	3	185	2	IPR019735
Domain	Synapsin_P_site	SYN1 SYN2	2.91e-04	3	185	2	IPR019736
Domain	Synapsin	SYN1 SYN2	2.91e-04	3	185	2	PF02078
Domain	Synapsin	SYN1 SYN2	2.91e-04	3	185	2	IPR001359
Domain	PreATP-grasp_dom	ACACA SYN1 SYN2	3.21e-04	14	185	3	IPR016185
Domain	WD40	MED16 STXBP5L KATNB1 PAAF1 SCAP DAW1 WDR87 SMU1 WDR12 DYNC1I1	3.51e-04	268	185	10	SM00320
Domain	WD40_repeat	MED16 STXBP5L KATNB1 PAAF1 SCAP DAW1 WDR87 SMU1 WDR12 DYNC1I1	3.94e-04	272	185	10	IPR001680
Domain	-	ACACA SYN1 SYN2	3.99e-04	15	185	3	3.30.1490.20
Domain	WD_REPEATS_1	MED16 STXBP5L KATNB1 PAAF1 SCAP DAW1 WDR87 SMU1 WDR12 DYNC1I1	4.68e-04	278	185	10	PS00678
Domain	WD_REPEATS_2	MED16 STXBP5L KATNB1 PAAF1 SCAP DAW1 WDR87 SMU1 WDR12 DYNC1I1	4.81e-04	279	185	10	PS50082
Domain	WD_REPEATS_REGION	MED16 STXBP5L KATNB1 PAAF1 SCAP DAW1 WDR87 SMU1 WDR12 DYNC1I1	4.81e-04	279	185	10	PS50294
Domain	Globin-like	HBG1 HBG2 HBZ	4.87e-04	16	185	3	IPR009050
Domain	PTR2_2	SLC15A1 SLC15A4	5.78e-04	4	185	2	PS01023
Domain	ATP_grasp_subdomain_1	ACACA SYN1 SYN2	6.99e-04	18	185	3	IPR013815
Domain	Terpenoid_cyclase/PrenylTrfase	ELMO2 C3 PZP	6.99e-04	18	185	3	IPR008930
Domain	-	ACACA SYN1 SYN2	6.99e-04	18	185	3	3.30.470.20
Domain	POT_fam	SLC15A1 SLC15A4	9.57e-04	5	185	2	IPR000109
Domain	PTR2	SLC15A1 SLC15A4	9.57e-04	5	185	2	PF00854
Domain	Sterol-sensing	SCAP NPC1L1	9.57e-04	5	185	2	PF12349
Domain	Haemoglobin_b	HBG1 HBG2	9.57e-04	5	185	2	IPR002337
Domain	WD40_repeat_CS	STXBP5L KATNB1 PAAF1 SCAP DAW1 SMU1 WDR12	1.26e-03	164	185	7	IPR019775
Domain	G-protein_beta_WD-40_rep	KATNB1 PAAF1 DAW1 SMU1 WDR12	1.56e-03	85	185	5	IPR020472
Domain	Glycoside_hydrolase_SF	HYAL4 GANC GBA3 FUCA1	1.87e-03	53	185	4	IPR017853
Domain	Plakophilin/d_Catenin	PKP1 CTNND1	1.98e-03	7	185	2	IPR028435
Pubmed	Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation.	DHFR DHFR2 HBG1 HBG2 HBZ	3.64e-08	18	189	5	9160753
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GPD2 FLII ACACA DIABLO RGS22 SPTBN1 EIF3E CAPZB APOB HUWE1 NCLN EPB41L3 NDUFS1 NMD3 GBA3 TGM3 CEBPZ CDC16 EIF3L RBPJ SMU1 PKP1 WDR12 CTNND1 NIPBL KPNA2	6.90e-08	1425	189	26	30948266
Pubmed	GTPase properties of the interferon-induced human guanylate-binding protein 2.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	8706832
Pubmed	Guanylate binding proteins contained in the murine chromosome 3 are important to control mycobacterial infection.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	32620042
Pubmed	[Guanylate-binding protein 2 regulates the maturation of mouse dendritic cells induced by β-glucan].	GBP1 GBP2 GBP3	1.58e-07	3	189	3	29089068
Pubmed	Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	1715024
Pubmed	Two families of GTPases dominate the complex cellular response to IFN-gamma.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	9862701
Pubmed	The interferon (IFN)-induced GTPase, mGBP-2. Role in IFN-gamma-induced murine fibroblast proliferation.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	11726669
Pubmed	GBP2 inhibits pathological angiogenesis in the retina via the AKT/mTOR/VEGFA axis.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	38636926
Pubmed	Inhibition of VSV and EMCV replication by the interferon-induced GTPase, mGBP-2: differential requirement for wild-type GTP binding domain.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	15717119
Pubmed	Subtyping of microsatellite stability colorectal cancer reveals guanylate binding protein 2 (GBP2) as a potential immunotherapeutic target.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	35383115
Pubmed	Role of GTP binding, isoprenylation, and the C-terminal α-helices in the inhibition of cell spreading by the interferon-induced GTPase, mouse guanylate-binding protein-2.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	20950129
Pubmed	Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative Pseudomonas aeruginosa.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	30062052
Pubmed	The chloride effect in the human embryonic haemoglobins.	HBG1 HBG2 HBZ	1.58e-07	3	189	3	7543751
Pubmed	Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	26416908
Pubmed	Guanylate-binding protein 2 orchestrates innate immune responses against murine norovirus and is antagonized by the viral protein NS7.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	32354743
Pubmed	Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	23248289
Pubmed	Domain motions, dimerization, and membrane interactions of the murine guanylate binding protein 2.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	36639389
Pubmed	The interferon-induced GTPase, mGBP-2, confers resistance to paclitaxel-induced cytotoxicity without inhibiting multinucleation.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	16914101
Pubmed	The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.	GBP1 GBP2 GBP3	1.58e-07	3	189	3	22730319
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	STXBP5L RIMS3 SPTBN1 SRC EPB41L3 SLC30A3 KCNMA1 SYN1 SYN2 MACF1 MICAL3 CTNND1	5.05e-07	347	189	12	17114649
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	SRC SLC6A15 APOB PARP14 CEMIP2 FAT1 SLC15A1 MICAL3 FLRT3 TAF2 CTNND1 HBG1 CXADR EPHA4 PSD4	5.98e-07	569	189	15	30639242
Pubmed	Embryonic hemoglobins in man and other mammals.	HBG1 HBG2 HBZ	6.29e-07	4	189	3	7008862
Pubmed	cDNA for the beta 1 subunit of guanyl nucleotide-binding regulatory proteins from mouse adrenal glands.	GBP1 GBP2 GBP3	6.29e-07	4	189	3	8917111
Pubmed	The Furin Protease Dependence and Antiviral GBP2 Sensitivity of Murine Leukemia Virus Infection Are Determined by the Amino Acid Sequence at the Envelope Glycoprotein Cleavage Site.	GBP1 GBP2 GBP3	6.29e-07	4	189	3	39337476
Pubmed	Interferon regulatory factor 1 is required for mouse Gbp gene activation by gamma interferon.	GBP1 GBP2 GBP3	6.29e-07	4	189	3	7823961
Pubmed	Dnmt1/Tet2-mediated changes in Cmip methylation regulate the development of nonalcoholic fatty liver disease by controlling the Gbp2-Pparγ-CD36 axis.	GBP1 GBP2 GBP3	6.29e-07	4	189	3	36609599
Pubmed	Genomic organization and chromosomal localization of a new member of the murine interferon-induced guanylate-binding protein family.	GBP1 GBP2 GBP3	6.29e-07	4	189	3	10386861
Pubmed	Guanylate-binding protein-5 is involved in inflammasome activation by bacterial DNA but only the cooperation of multiple GBPs accounts for control of Brucella abortus infection.	GBP1 GBP2 GBP3	6.29e-07	4	189	3	38404575
Pubmed	Murine GBP-2: a new IFN-gamma-induced member of the GBP family of GTPases isolated from macrophages.	GBP1 GBP2 GBP3	1.57e-06	5	189	3	9858320
Pubmed	TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2.	GBP1 GBP2 GBP3	1.57e-06	5	189	3	30858199
Pubmed	Murine GBP-5, a new member of the murine guanylate-binding protein family, is coordinately regulated with other GBPs in vivo and in vitro.	GBP1 GBP2 GBP3	1.57e-06	5	189	3	12396730
Pubmed	Unique features of different members of the human guanylate-binding protein family.	GBP1 GBP2 GBP3	1.57e-06	5	189	3	17266443
Pubmed	A molecular analysis of mouse development from 8 to 10 days post coitum detects changes only in embryonic globin expression.	HBG1 HBG2 HBZ	1.57e-06	5	189	3	2444404
Pubmed	Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.	GBP1 GBP2 GBP3	1.57e-06	5	189	3	21151871
Pubmed	Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection.	GBP1 GBP2 GBP3	1.57e-06	5	189	3	31964735
Pubmed	Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.	HBG1 HBG2 HBZ	1.57e-06	5	189	3	8901585
Pubmed	The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation.	GBP1 GBP2 GBP3 PARP14	2.44e-06	18	189	4	27001747
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIAA0232 RIMS3 ARHGEF17 TRAK1 FCHSD2 TENM4 LGI2 GPCPD1 MACF1 CACNA1H MICAL3 PCNT	2.65e-06	407	189	12	12693553
Pubmed	Targeted disruption of the CP2 gene, a member of the NTF family of transcription factors.	HBG1 HBG2 HBZ	3.12e-06	6	189	3	10995745
Pubmed	An extra-erythrocyte role of haemoglobin body in chondrocyte hypoxia adaption.	HBG1 HBG2 HBZ	3.12e-06	6	189	3	37794190
Pubmed	"Maturational" globin switching in primary primitive erythroid cells.	HBG1 HBG2 HBZ	3.12e-06	6	189	3	16263786
Pubmed	Separation of zeta (zeta) and various gamma (gamma) chains of human embryonic hemoglobin Portland I by reverse-phase high-performance liquid chromatography.	HBG1 HBG2 HBZ	3.12e-06	6	189	3	6683087
Pubmed	Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy.	GBP1 GBP2 GBP3	3.12e-06	6	189	3	21757726
Pubmed	Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene.	GBP1 GBP2 GBP3	3.12e-06	6	189	3	17293456
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ACACA SPTBN1 EIF3E DIDO1 HUWE1 EPB41L3 NDUFS1 TGM3 CEBPZ EIF3L SMU1 MACF1 WDR12 NIPBL PCNT	3.25e-06	653	189	15	22586326
Pubmed	Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion.	GBP1 GBP2 GBP3 TLR3	3.82e-06	20	189	4	32150572
Pubmed	TRIF signaling is required for caspase-11-dependent immune responses and lethality in sepsis.	GBP1 GBP2 GBP3	5.44e-06	7	189	3	30587103
Pubmed	The interferon-gamma-induced GTPase, mGBP-2, inhibits tumor necrosis factor alpha (TNF-alpha) induction of matrix metalloproteinase-9 (MMP-9) by inhibiting NF-kappaB and Rac protein.	GBP1 GBP2 GBP3	5.44e-06	7	189	3	21502320
Pubmed	The interferon-gamma-induced murine guanylate-binding protein-2 inhibits rac activation during cell spreading on fibronectin and after platelet-derived growth factor treatment: role for phosphatidylinositol 3-kinase.	GBP1 GBP2 GBP3	5.44e-06	7	189	3	20505078
Pubmed	Sox6 directly silences epsilon globin expression in definitive erythropoiesis.	HBG1 HBG2 HBZ	5.44e-06	7	189	3	16462943
Pubmed	Mechanisms of developmental control of transcription in the murine alpha- and beta-globin loci.	HBG1 HBG2 HBZ	5.44e-06	7	189	3	9887104
Pubmed	UCP2 modulates cell proliferation through the MAPK/ERK pathway during erythropoiesis and has no effect on heme biosynthesis.	HBG1 HBG2 HBZ	8.67e-06	8	189	3	18687678
Pubmed	In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.	GBP1 GBP2 GBP3	8.67e-06	8	189	3	16689661
Pubmed	Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.	ABCC9 HNMT NDUFS1 SLC22A7 ALDH1A2 SLC15A1 ABCA5 TAP1	1.15e-05	193	189	8	19343046
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	HIVEP2 AP4E1 PTPRD CDC16 MARF1 SYN1 SYN2 MACF1 CTNND1 ESPL1	1.18e-05	322	189	10	26514267
Pubmed	The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.	GPD2 FLII SPTBN1 QTRT2 DIDO1 HUWE1 PAAF1 CEMIP2 CTNND1 KPNA2	1.27e-05	325	189	10	36168628
Pubmed	Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.	HBG1 HBG2 HBZ	1.30e-05	9	189	3	7926723
Pubmed	Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.	GBP1 GBP2 GBP3	1.30e-05	9	189	3	24739961
Pubmed	Peroxidase activity of hemoglobin-haptoglobin complexes: covalent aggregation and oxidative stress in plasma and macrophages.	HBG1 HBG2 HBZ	1.30e-05	9	189	3	19740759
Pubmed	Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor.	HBG1 HBG2 HBZ	1.30e-05	9	189	3	9159135
Pubmed	3' non-coding region sequences in eukaryotic messenger RNA.	HBG1 HBG2 HBZ	1.30e-05	9	189	3	822353
Pubmed	Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins.	GBP1 GBP2 GBP3	1.30e-05	9	189	3	33479228
Pubmed	Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencing.	HBG1 HBG2 HBZ	1.30e-05	9	189	3	23716600
Pubmed	Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL.	HBG1 HBG2 HBZ	1.30e-05	9	189	3	7830794
Pubmed	Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion.	HBG1 HBG2 HBZ	1.30e-05	9	189	3	9887098
Pubmed	Inactivation of G-protein-coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis at midgestation through down-regulation of the ATF4 signaling pathway.	HBG1 HBG2 HBZ	1.30e-05	9	189	3	18955481
Pubmed	Role of the GATA-1/FOG-1/NuRD pathway in the expression of human beta-like globin genes.	HBG1 HBG2 HBZ	1.30e-05	9	189	3	20439494
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	FLII ACACA STXBP5L ADCK1 SPTBN1 VPS33A HUWE1 NCLN EPB41L3 NDUFS1 TENM4 CDC16 SNX25 PKP1 SYN2 MACF1 ACTL6B CTNND1 CXADR	1.60e-05	1139	189	19	36417873
Pubmed	KLF2 is essential for primitive erythropoiesis and regulates the human and murine embryonic beta-like globin genes in vivo.	HBG1 HBG2 HBZ	1.84e-05	10	189	3	15947087
Pubmed	The human plasma proteome: history, character, and diagnostic prospects.	GBP1 HBG1 HBG2	1.84e-05	10	189	3	12488461
Pubmed	EKLF and KLF2 have compensatory roles in embryonic beta-globin gene expression and primitive erythropoiesis.	HBG1 HBG2 HBZ	1.84e-05	10	189	3	17675555
Pubmed	Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.	GBP1 GBP2 GBP3	1.84e-05	10	189	3	28334111
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	GPD2 LEO1 SPTBN1 SLC6A15 HUWE1 PAAF1 CEMIP2 ARID1B PTPRD SMG7 PTPRH CEBPZ KCNMA1 MICAL3 CTNND1 CXADR PCNT KPNA2	1.87e-05	1049	189	18	27880917
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	CCHCR1 ACACA KIAA0232 RNF135 KATNB1 CAPZB AP4E1 TGM3 ALDH1A2 SMG7 ELMO2 MICAL3 TAF2 PDZRN3 DYNC1I1 PCNT	1.91e-05	853	189	16	28718761
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	DIDO1 HUWE1 ARHGEF17 TRANK1 CTNND1 DNAH9	2.32e-05	104	189	6	9205841
Pubmed	Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF.	HBG1 HBG2 HBZ	2.52e-05	11	189	3	7753195
Pubmed	Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.	GBP1 GBP2 GBP3	2.52e-05	11	189	3	24715728
Pubmed	The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development.	HBG1 HBG2 HBZ	2.52e-05	11	189	3	18094026
Pubmed	IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.	GBP1 GBP2 GBP3	2.52e-05	11	189	3	27693356
Pubmed	Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.	GBP1 GBP2 GBP3	2.52e-05	11	189	3	18025219
Pubmed	Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.	SLC6A15 NCLN ELMO2 MACF1 CTNND1 TAP1 CXADR	2.90e-05	160	189	7	31678930
Pubmed	Seizure elements and seizure element transitions during tonic-clonic seizure activity in the synapsin I/II double knockout mouse: a neuroethological description.	SYN1 SYN2	2.94e-05	2	189	2	19236947
Pubmed	Variation in Niemann-Pick C1-like 1 gene as a determinant of apolipoprotein B-100 kinetics and response to statin therapy in centrally obese men.	APOB NPC1L1	2.94e-05	2	189	2	18031309
Pubmed	Dimerization and its role in GMP formation by human guanylate binding proteins.	GBP1 GBP2	2.94e-05	2	189	2	20923658
Pubmed	The importance of synapsin I and II for neurotransmitter levels and vesicular storage in cholinergic, glutamatergic and GABAergic nerve terminals.	SYN1 SYN2	2.94e-05	2	189	2	19428802
Pubmed	Two novel arrangements of the human fetal globin genes: G gamma-G gamma and A gamma-A gamma.	HBG1 HBG2	2.94e-05	2	189	2	6091051
Pubmed	Synapsin-dependent development of glutamatergic synaptic vesicles and presynaptic plasticity in postnatal mouse brain.	SYN1 SYN2	2.94e-05	2	189	2	18606212
Pubmed	An embryonic stage-specific enhancer within the murine β-globin locus mediates domain-wide histone hyperacetylation.	HBG1 HBG2	2.94e-05	2	189	2	21321362
Pubmed	Glutamatergic neurotransmission in the synapsin I and II double knock-out mouse.	SYN1 SYN2	2.94e-05	2	189	2	21827868
Pubmed	A study on the genotype frequency of -158 Gγ (C→T) Xmn1 polymorphism in a sickle cell trait cohort from Siwa Oasis, Egypt.	HBG1 HBG2	2.94e-05	2	189	2	29932071
Pubmed	Synapsins I and II are ATP-binding proteins with differential Ca2+ regulation.	SYN1 SYN2	2.94e-05	2	189	2	9430678
Pubmed	Mechanism for fetal globin gene expression: role of the soluble guanylate cyclase-cGMP-dependent protein kinase pathway.	HBG1 HBG2	2.94e-05	2	189	2	11172039
Pubmed	Sequences of G gamma, A gamma, and beta genes of the Greek (A gamma) HPFH mutant: evidence for a distal CCAAT box mutation in the A gamma gene.	HBG1 HBG2	2.94e-05	2	189	2	2413469
Pubmed	Synapsin II and calcium regulate vesicle docking and the cross-talk between vesicle pools at the mouse motor terminals.	SYN1 SYN2	2.94e-05	2	189	2	18669537
Pubmed	Synapsins regulate use-dependent synaptic plasticity in the calyx of Held by a Ca2+/calmodulin-dependent pathway.	SYN1 SYN2	2.94e-05	2	189	2	16481620
Pubmed	Two mouse early embryonic beta-globin gene sequences. Evolution of the nonadult beta-globins.	HBG1 HBG2	2.94e-05	2	189	2	6323438
Pubmed	Human fetal hemoglobin F 1. Acetylation status.	HBG1 HBG2	2.94e-05	2	189	2	5554303
Pubmed	Effect of HIV type 1 Tat protein on butyric acid-induced differentiation in a hematopoietic progenitor cell line.	HBG1 HBG2	2.94e-05	2	189	2	8911578
Pubmed	Low voltage activation of KCa1.1 current by Cav3-KCa1.1 complexes.	KCNMA1 CACNA1H	2.94e-05	2	189	2	23626738
Interaction	GBP3 interactions	GBP1 GBP2 GBP3 ACTL6B	1.30e-06	10	182	4	int:GBP3
Cytoband	1p22.2	GBP1 GBP2 GBP3	2.09e-04	28	189	3	1p22.2
Cytoband	4p15.2	GBA3 LGI2 RBPJ	2.09e-04	28	189	3	4p15.2
GeneFamily	WD repeat domain containing	MED16 STXBP5L KATNB1 PAAF1 SCAP DAW1 WDR87 SMU1 WDR12 DYNC1I1	1.63e-05	262	127	10	362
GeneFamily	Hemoglobin subunits	HBG1 HBG2 HBZ	3.92e-05	10	127	3	940
GeneFamily	Solute carriers	SLC26A9 SLC6A15 SLC30A3 SLC22A7 SLC13A4 SLC15A1 SLC15A4 SLC25A2 SLC16A14 SLC28A2 SLC5A8	1.09e-04	395	127	11	752
GeneFamily	Synapsins	SYN1 SYN2	1.46e-04	3	127	2	1325
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C3 PZP	1.71e-03	9	127	2	1234
GeneFamily	Maestro heat like repeat containing	MROH5 MROH2B	2.58e-03	11	127	2	636
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PKP1 CTNND1 KPNA2	3.40e-03	43	127	3	409
GeneFamily	Eukaryotic translation initiation factor 3	EIF3E EIF3L	3.63e-03	13	127	2	1121
Coexpression	GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_UP	GPD2 HIVEP2 GBP2 GBP3 SLC6A15 PARP14 HEATR6 FLRT3 TAP1	2.87e-06	163	188	9	M8663
Coexpression	GSE27786_CD4_VS_CD8_TCELL_DN	ACACA EIF3E SCAP ELMO2 EIF3L SMU1 HBG2 KLRD1 DYNC1I1	1.45e-05	199	188	9	M4821
Coexpression	GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_DN	LYPLAL1 FSTL4 OIP5 GGT5 SNX25 SLC16A14 DHFR CTNND1 ESPL1	1.45e-05	199	188	9	M3420
Coexpression	HEVNER_TELENCEPHALON_ERYTHROCYTES	HBG1 HBG2 HBZ	1.98e-05	8	188	3	MM389
Coexpression	HE_LIM_SUN_FETAL_LUNG_C2_CXCL9_POS_MACROPHAGE_CELL	HIVEP2 SRC GBP1 GBP2 GBP3 GGT5 TAP1	3.59e-05	126	188	7	M45721
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STXBP5L RGS22 ANO5 APOB FAT1 TRANK1 TENM4 PTPRD ASXL3 ADAMTS20 DNAH9	4.08e-10	184	188	11	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STXBP5L RGS22 ANO5 APOB FAT1 TRANK1 TENM4 PTPRD ASXL3 ADAMTS20 DNAH9	4.08e-10	184	188	11	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STXBP5L RGS22 ANO5 APOB FAT1 TRANK1 TENM4 PTPRD ASXL3 ADAMTS20 DNAH9	4.08e-10	184	188	11	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STXBP5L FSTL4 SLC6A15 TGM3 EYS CACNA1H ACTL6B SLC5A8 C6orf141	6.08e-08	175	188	9	182e45f5c02214d6b9f317ff5dc43af8b42de978
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	HIVEP2 SLC26A9 ABCC9 IQCN CEMIP2 CLIC2 SNX25 SLC5A8 EPHA4	1.07e-07	187	188	9	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	facs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP1 SLC26A9 ANO5 TRANK1 SLC25A2 KCNMA1 DNAH9 KCNH5	1.58e-07	141	188	8	4aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCell	facs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP1 SLC26A9 ANO5 TRANK1 SLC25A2 KCNMA1 DNAH9 KCNH5	1.58e-07	141	188	8	e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	GBP1 GBP2 GBP3 PARP14 NOD1 TRANK1 PGAP1 DNAH9	9.71e-07	179	188	8	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	COPD-Epithelial-PNEC\|Epithelial / Disease state, Lineage and Cell class	STXBP5L ANO5 ASXL3 KCNMA1 CACNA1H PDZRN3 DYNC1I1 HCRT	9.71e-07	179	188	8	988d0853c391da1e5004f73f3678047418d3f6d3
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DIABLO STXBP5L OR2A5 TGM3 EYS SYN2 SLC5A8 C6orf141	9.71e-07	179	188	8	8ce5000088b727783a0619baa16a2cd036d21f54
ToppCell	Multiple_Sclerosis-Other-RBC\|Multiple_Sclerosis / Disease, Lineage and Cell Type	TMPRSS9 DPCD RGS6 CLIC2 WDR87 HBG1 HBG2 HBZ	9.71e-07	179	188	8	15763dc59ee6186416e203ffbb450ae4608eba59
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STXBP5L FAM135B TRANK1 RGS6 TLL1 KCNMA1 SYN2 DYNC1I1	1.30e-06	186	188	8	d6c8ce2a32c218dcc63d861cc247152430ed3c8c
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	REP15 SPTBN1 PKD1L3 GGT5 ADAMTS20 MACF1 EFCC1 C6orf141	1.30e-06	186	188	8	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	GBP1 GBP2 GBP3 PARP14 NOD1 TRANK1 PGAP1 TAP1	1.40e-06	188	188	8	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	STXBP5L RIMS3 FSTL4 SLC30A3 RGS6 PTPRD PDZRN3 EPHA4	1.84e-06	195	188	8	787e95fb59c40bba784544b662fac37606ae1427
ToppCell	Bronchus_Control_(B.)-Endothelial-TX\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	RGS6 SLC15A1 PKP1 PYGM CACNA1H FLRT3 ESPL1 C6orf141	2.07e-06	198	188	8	feac39036b5c0ab97b524cc366286942d136d42f
ToppCell	Bronchus_Control_(B.)-Endothelial-TX-Bronchial_vessel\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	FAT1 RGS6 SLC15A1 PKP1 CACNA1H FLRT3 ESPL1 C6orf141	2.07e-06	198	188	8	dcf334d13e5b0018fee24febccfef91c9e17843b
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	TMPRSS9 EIF3E LPAR1 ALDH1A2 PTPRD MACF1 EFCC1 PZP	2.15e-06	199	188	8	c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T\|COVID-19_Mild / Disease, condition lineage and cell class	HIVEP2 RIMS3 SPTBN1 GBP1 GBP2 TRANK1 SMG7 MACF1	2.15e-06	199	188	8	f307d4887b28cf60a591439e278fd668409cb104
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	TMPRSS9 LPAR1 ALDH1A2 PTPRD MACF1 EFCC1 PZP PDZRN3	2.23e-06	200	188	8	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	HIVEP2 SPTBN1 GBP3 PARP14 CEMIP2 MACF1 CTNND1 TAP1	2.23e-06	200	188	8	2d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	HIVEP2 SPTBN1 GBP3 PARP14 CEMIP2 MACF1 CTNND1 TAP1	2.23e-06	200	188	8	edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	TMPRSS9 LPAR1 ALDH1A2 PTPRD MACF1 EFCC1 PZP PDZRN3	2.23e-06	200	188	8	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	TMPRSS9 LPAR1 ALDH1A2 PTPRD MACF1 EFCC1 PZP PDZRN3	2.23e-06	200	188	8	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	facs-Heart-Unknown-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP1 SLC26A9 ANO5 TRANK1 SLC25A2 KCNMA1 KCNH5	2.46e-06	142	188	7	759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell	LPS-IL1RA-Myeloid_granulocytic-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPLAL1 HEATR4 ABCA5 DAW1 CHFR SYN1 PSD4	4.21e-06	154	188	7	43735f7c58cac51855ded486ee8d8729a1b9909e
ToppCell	LPS-IL1RA-Myeloid_granulocytic\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPLAL1 HEATR4 ABCA5 DAW1 CHFR SYN1 PSD4	4.21e-06	154	188	7	d55fb73461885e1e02061a344ff89624ef4de487
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	REP15 SPTBN1 PKD1L3 GGT5 MACF1 EFCC1 C6orf141	1.09e-05	178	188	7	ad3de3e03a401dac64431a541899445262246347
ToppCell	facs-Marrow-KLS-24m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMS22L LEO1 DPCD AASDH TMEM269 FLRT3 CTNND1	1.13e-05	179	188	7	5297f7459b40ca780a1983fecc1bb9c035c7677e
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SERPINE3 ALDH1A2 DAW1 ADAMTS20 C3 FLRT3 CXADR	1.13e-05	179	188	7	056df2aaff750e0e283e7da78fcc3c90c366aac0
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SERPINE3 ALDH1A2 DAW1 ADAMTS20 C3 FLRT3 CXADR	1.13e-05	179	188	7	f5f3945ef3b9efc5921a71fd51deeb2c80f0ce11
ToppCell	18-Airway-RBC\|Airway / Age, Tissue, Lineage and Cell class	TMPRSS9 GANC RGS6 LGI2 HBG1 HBG2 HBZ	1.17e-05	180	188	7	35bf5f35cf346a5b27f5e819b77db34130d70db1
ToppCell	18-Airway-RBC-RBC\|Airway / Age, Tissue, Lineage and Cell class	TMPRSS9 GANC RGS6 LGI2 HBG1 HBG2 HBZ	1.17e-05	180	188	7	3b4b220a3c150426ae55239baff756f1a7f1e1d7
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-mesothelial_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGS22 ALDH1A2 DAW1 ADAMTS20 C3 FLRT3 KCNH5	1.21e-05	181	188	7	65eaa9bc1022bcf0c5f0f92c07a2cbbf11f9b59c
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(PRG4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGS22 ALDH1A2 DAW1 ADAMTS20 C3 FLRT3 KCNH5	1.21e-05	181	188	7	eaac7d58117eddfff06b25521efc431c1351d592
ToppCell	CV-Healthy-7\|CV / Virus stimulation, Condition and Cluster	MMS22L NDUFS1 AP4E1 SNX25 CARF TLR3 MICAL3	1.35e-05	184	188	7	0e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell	COVID-19-kidney-PCT-S1/S2\|kidney / Disease (COVID-19 only), tissue and cell type	EPB41L3 SLC22A7 PTPRD SLC15A1 SYN2 SLC5A8 PDZRN3	1.35e-05	184	188	7	dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STXBP5L FAM135B RGS6 TLL1 KCNMA1 SYN2 DYNC1I1	1.39e-05	185	188	7	70de48988c1f8e0809afc8092b663aa439d8e528
ToppCell	CV-Healthy-7\|Healthy / Virus stimulation, Condition and Cluster	MMS22L NDUFS1 AP4E1 SNX25 CARF TLR3 MICAL3	1.39e-05	185	188	7	1979d189c204f4c2893e3170a514ee7d5523406c
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GBP1 GBP2 GBP3 PARP14 SCARF1 TRANK1 TAP1	1.39e-05	185	188	7	f30fb9d75cdb757b206312992aaf7485bc900f96
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Sema3e\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TMPRSS9 MROH5 APOB CLCA1 NPC1L1	1.44e-05	73	188	5	51bcbb57ee6c45cad88cb3e2cedab2cf3503b2a5
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	STXBP5L RIMS3 FSTL4 SLC30A3 RGS6 EPHA4 KCNH5	1.44e-05	186	188	7	bdbe290f81106a53c8c30a92fbb385597c62b2ac
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STXBP5L FAM135B RGS6 TLL1 KCNMA1 SYN2 DYNC1I1	1.50e-05	187	188	7	7b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	STXBP5L RIMS3 FSTL4 SLC30A3 RGS6 PTPRD EPHA4	1.50e-05	187	188	7	f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	STXBP5L FSTL4 SLC30A3 RGS6 PTPRD EPHA4 KCNH5	1.55e-05	188	188	7	50c1b1d690f0e9443082f2adf4f1b8e9ce4cd337
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	HUWE1 PARP14 CEMIP2 ARID1B GPCPD1 MACF1 NIPBL	1.55e-05	188	188	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	facs-Lung-EPCAM-18m-Epithelial-Basal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPB41L3 FAT1 ALDH1A2 SCNN1B PKP1 SLC5A8 CXADR	1.60e-05	189	188	7	783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	STXBP5L RIMS3 FSTL4 SLC30A3 RGS6 PTPRD EPHA4	1.60e-05	189	188	7	c3df0e3c50af8f1cfb4d790e668bd7f42b276992
ToppCell	facs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPB41L3 FAT1 ALDH1A2 SCNN1B PKP1 SLC5A8 CXADR	1.60e-05	189	188	7	88b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(MGE-derived_cortical_interneurons)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TMEM269 CD226 ZSCAN30 SLC25A2 PZP	1.64e-05	75	188	5	6339b514a98511e409d86d4b9d460afe192557c0
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(MGE-derived_cortical_interneurons)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TMEM269 CD226 ZSCAN30 SLC25A2 PZP	1.64e-05	75	188	5	a5bef117c483ce5afc38d96709370e8e53f4f2a9
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Th.Nr4a2_(MGE-derived_cortical_interneurons)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TMEM269 CD226 ZSCAN30 SLC25A2 PZP	1.64e-05	75	188	5	75181a17aca2482f18f23beb31983d01043e02cb
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel\|Adult / Lineage, Cell type, age group and donor	REP15 PKD1L3 TLL1 EFCC1 MICAL3 C6orf141 DYNC1I1	1.66e-05	190	188	7	91bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCC9 ARHGEF17 FAT1 LGI2 KCNMA1 PZP PDZRN3	1.71e-05	191	188	7	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	15-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	SLC26A9 FAM135B ACTL6B OTULINL ESPL1 TNR KCNH5	1.71e-05	191	188	7	76311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCell	IPF-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	ACACA IQCN HNMT GGT5 PTPRD SCNN1B C3	1.77e-05	192	188	7	356e7a820b744a0ac87352a8d0e6e8d9fa9ed7d2
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	PLEKHB2 GPD2 E2F7 GBP1 QTRT2 PARP14 TAP1	1.77e-05	192	188	7	4e689bca7a242f8482e25f273656e2caba8821c0
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 STXBP5L FSTL4 SLC30A3 TRANK1 TENM4 SYN2	1.83e-05	193	188	7	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 STXBP5L FSTL4 SLC30A3 TRANK1 TENM4 SYN2	1.83e-05	193	188	7	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	LA-14._Fibroblast_III\|LA / Chamber and Cluster_Paper	HIVEP2 EPB41L3 LPAR1 ARID1B PGAP1 GPCPD1 C3	1.83e-05	193	188	7	7426c291bac59e539c427bcaae18abc7d397d44e
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 STXBP5L FSTL4 SLC30A3 TRANK1 TENM4 SYN2	1.83e-05	193	188	7	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	LA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	HIVEP2 EPB41L3 LPAR1 ARID1B PGAP1 GPCPD1 C3	1.89e-05	194	188	7	803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCell	cellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RGS22 DPCD DNAH2 AK7 DAW1 FAM227A DNAH9	1.96e-05	195	188	7	d8bf15aa7cdbc5f29b58e1e6cff76c257f0ea12e
ToppCell	cellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RGS22 DPCD DNAH2 AK7 DAW1 FAM227A DNAH9	1.96e-05	195	188	7	e7f069f557a59ee7b502ff82ad4c9f47fa619ba8
ToppCell	Mild-CD8+_T_activated\|World / Disease group and Cell class	GBP1 PARP14 TRANK1 CD226 PGAP1 TAP1 KLRD1	2.02e-05	196	188	7	79632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SPTBN1 LPAR1 PTPRD ASXL3 MACF1 PDZRN3 DYNC1I1	2.09e-05	197	188	7	11a4c417f035e554431a8f03be13b5eefa3530c0
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH2 AK7 CLCA1 PKP1 FAM227A C3 DNAH9	2.16e-05	198	188	7	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	Mild-CD8+_T_activated\|Mild / Disease group and Cell class	GBP1 GBP2 PARP14 TRANK1 CD226 PGAP1 TAP1	2.16e-05	198	188	7	ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_macrophage\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SRC EPB41L3 HNMT CLIC2 KCNMA1 FUCA1 CTNND1	2.16e-05	198	188	7	9aaff68107ae4542f904b142d23669f2fcd557ac
ToppCell	Control-Control-Lymphocyte-T/NK-CD4+_T_activated\|Control / Disease, condition lineage and cell class	HIVEP2 SPTBN1 GBP1 GBP2 TRANK1 PGAP1 MACF1	2.16e-05	198	188	7	ee71543559836fd59adc0da877b2ca538cba60cb
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH2 AK7 CLCA1 PKP1 FAM227A C3 DNAH9	2.16e-05	198	188	7	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SRC EPB41L3 HNMT CLIC2 KCNMA1 FUCA1 CTNND1	2.16e-05	198	188	7	5aaf3861c53763cf09bb628c9d2eabb6a7277021
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FSTL4 SLC6A15 TENM4 ASXL3 PGAP1 PKP1 FLRT3	2.23e-05	199	188	7	94a7867e800df352731796de8c24cba133c29622
ToppCell	proximal-Epithelial-Ciliated\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RGS22 DNAH2 AK7 DAW1 FAM227A PZP DNAH9	2.23e-05	199	188	7	9700f06e51ddca85e482b4f9bd4a79bfcd3cfb76
ToppCell	LPS_anti-TNF-Epithelial_airway\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DNAH2 AK7 CLCA1 SCNN1B PKP1 C3 DNAH9	2.23e-05	199	188	7	6aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-Cilia-bearing_cell\|10w / Sample Type, Dataset, Time_group, and Cell type.	ZYG11A GBP1 AK7 GGT5 SLC13A4 DAW1 DNAH9	2.23e-05	199	188	7	2d8ab4aee300c7c4baf662940ce855da2b6d2cae
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DNAH2 AK7 CLCA1 SCNN1B PKP1 C3 DNAH9	2.23e-05	199	188	7	60919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell	proximal-3-Epithelial-Ciliated\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RGS22 DNAH2 AK7 DAW1 FAM227A PZP DNAH9	2.23e-05	199	188	7	1188afad6fd5f01f9aeba225f611f38b237dd2c9
ToppCell	proximal-Epithelial-Ciliated-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RGS22 DNAH2 AK7 DAW1 FAM227A PZP DNAH9	2.23e-05	199	188	7	2e8ace105c4e2405baa06d953e52888b54e2d055
ToppCell	distal-3-Hematologic-Platelet/Megakaryocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAH2 AK7 TGM3 SLC15A1 DAW1 PZP DNAH9	2.30e-05	200	188	7	f5f5a8b0e4d802d95dc42646dd5e7d7daaad72b4
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Cortical_neuron\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	SPTBN1 EPB41L3 PTPRD ASXL3 ACTL6B DYNC1I1 CXADR	2.30e-05	200	188	7	44bc4d6616fc8d0ad8498e56125939034e8cff01
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RGS22 DNAH2 AK7 DAW1 FAM227A PZP DNAH9	2.30e-05	200	188	7	85c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RGS22 DNAH2 AK7 DAW1 FAM227A PZP DNAH9	2.30e-05	200	188	7	12bc7d95c4166d12487081a76d210b7abe5991b0
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FSTL4 EPB41L3 TMEM269 PTPRH ABCA5 PMP2	2.57e-05	137	188	6	85b3a98039c1f68addad0334aa5b2584f6045aaa
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	PAPPA2 CEMIP2 CD226 PGAP1 MACF1 BRD1	4.43e-05	151	188	6	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-Teffector/EM_CD4\|GI_large-bowel / Manually curated celltypes from each tissue	ADCK1 USP44 SLC28A2 PZP CXADR EPHA4	5.31e-05	156	188	6	01f2c0c6a936dfb59bc727feef428a906ad2a80b
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GBP1 GBP3 PKD1L3 PARP14 TRANK1 TAP1	6.77e-05	163	188	6	d005115aa1e1458b51de7eb719794617a4168608
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHB2 EPB41L3 TENM4 SNX25 SLC28A2 SYN1	6.77e-05	163	188	6	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RIMS3 FSTL4 TENM4 PDZRN3 EPHA4 KCNH5	6.77e-05	163	188	6	431221a41d396b09170476179590eaf8a55266d8
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RIMS3 FSTL4 TENM4 PDZRN3 EPHA4 KCNH5	6.77e-05	163	188	6	1e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHB2 EPB41L3 TENM4 SNX25 SLC28A2 SYN1	6.77e-05	163	188	6	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GBP2 GBP3 PARP14 SMG7 FAM227A MANSC4	7.75e-05	167	188	6	774f3264318b002d0df5d06d41d645366038d0bf
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP1 EPB41L3 PKD1L3 ALDH1A2 PTPRH TNR	8.54e-05	170	188	6	a121e10099faaeb60251eec162f38caf7c4238c2
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL4 ABCC9 SLC30A3 TLL1 EPHA4 KCNH5	9.11e-05	172	188	6	41ddfb316429efef5f3fa0b0621ced383d9206f0
ToppCell	normal_Lung-T/NK_cells-Exhausted_Tfh\|normal_Lung / Location, Cell class and cell subclass	GTPBP6 RIMS3 NDUFAF7 RBPJ TAP1 KPNA2	9.41e-05	173	188	6	e8ead6c51c41dbd43c717ba9d1a7a0ab39c79330
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FSTL4 SLC6A15 EYS CACNA1H ACTL6B C6orf141	9.71e-05	174	188	6	9f114e61458659005b6d0b4aa30a7a059e7aa5c6
ToppCell	wk_20-22-Hematologic-Myeloid-CXCL9+_Mac\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SRC GBP1 GBP2 PARP14 GGT5 TAP1	1.00e-04	175	188	6	48f5bdbfc1ba40c3fb6411f12a69e61da2138296
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	STXBP5L FSTL4 ANO5 ASXL3 TNR DYNC1I1	1.00e-04	175	188	6	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	STXBP5L FSTL4 ANO5 ASXL3 TNR DYNC1I1	1.00e-04	175	188	6	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HYAL4 STXBP5L FSTL4 EYS ALDH1A2 SYN1	1.00e-04	175	188	6	97a58bc6ed2e8e359283d4214172c990c6e3755e
Drug	AC1NSXE4	GANC APOB GBA3 SLC5A8	4.22e-06	14	188	4	CID005318881
Drug	2-desamino-2-methylaminopterin	GGT5 DHFR DHFR2	5.47e-06	5	188	3	CID000164085
Drug	Ranitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A	ITFG2 SPTBN1 SRC ARHGEF17 HNMT NOD1 SMG7 PGAP1 MACF1 PSD4	5.62e-06	196	188	10	5425_DN
Drug	Proparacaine hydrochloride [5875-06-9]; Down 200; 12uM; PC3; HT_HG-U133A	GPD2 TBC1D9B ITFG2 KIAA0232 SPTBN1 SMG7 ELMO2 NDUFAF7 NIPBL DYNC1I1	6.15e-06	198	188	10	6332_DN
Drug	formamide	HNMT ACTL6B POLN HBG1 HBG2 HBZ PMP2	6.71e-06	85	188	7	CID000000713
Drug	homonojirimycin	GANC GBA3 PYGM FUCA1	9.85e-06	17	188	4	CID000159496
Drug	AC1NSXES	GANC GBA3 SLC5A8	1.09e-05	6	188	3	CID005318890
Drug	acarbose	GANC APOB GBA3 PYGM HBG1 HBG2 HBZ	1.31e-05	94	188	7	CID000041774
Drug	glibenclamide	GPD2 GANC SLC26A9 ABCC9 APOB CLCA1 ABCA5 CLIC2 KCNMA1 SCNN1B HBG1 HBG2 HBZ	1.86e-05	382	188	13	CID000003488
Drug	glucitollysine	APOB HBG1 HBG2 HBZ	1.97e-05	20	188	4	CID000122288
Drug	1 sulfonylurea	GPD2 ACACA GANC ABCC9 APOB HBG1 HBG2 HBZ	2.56e-05	143	188	8	CID011819083
Drug	Glyset	GANC GBA3 HBG1 HBG2 HBZ	2.72e-05	43	188	5	CID000051577
Drug	metformin	GPD2 ACACA GANC APOB AK7 SLC28A2 CTNND1 HBG1 HBG2 HBZ	2.72e-05	235	188	10	CID000004091
Drug	trimethylamine-cyanoborane	ACACA DHFR DHFR2	3.01e-05	8	188	3	CID006328234
Drug	NSC23615	DIABLO APOB DHFR CARF DHFR2 SLC28A2 PYGM FUCA1 POLN	3.39e-05	193	188	9	CID000000640
Drug	alpha-AASA	ACACA AASDH HBG1 HBG2 HBZ	3.40e-05	45	188	5	CID000000207
Drug	CP-320650-01 [172079-28-6]; Down 200; 1uM; PC3; HT_HG-U133A	ITFG2 MED16 STXBP5L VPS33A SRC CD101 SCNN1B ADAMTS20 PSD4	3.98e-05	197	188	9	3825_DN
Drug	gamma-aminobutyric acid	ACACA LEO1 SLC6A15 PKD1L3 TRAK1 CLCA1 CLIC2 KCNMA1 SYN1 SYN2 CACNA1H TAP1 HCRT CXADR	4.23e-05	474	188	14	CID000000119
Drug	Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; PC3; HT_HG-U133A	RIMS3 CEMIP2 TENM4 SMG7 ELMO2 KCNMA1 MICAL3 ESPL1 DYNC1I1	4.30e-05	199	188	9	6308_DN
Drug	Drofenine hydrochloride [548-66-3]; Down 200; 11.4uM; PC3; HT_HG-U133A	TBC1D9B HIVEP2 KIAA0232 TRAK1 HEATR6 TENM4 FLRT3 BRD1 NIPBL	4.48e-05	200	188	9	7129_DN
Drug	AC1L9FD9	GANC SLC15A1 HBG1 HBG2 HBZ	4.67e-05	48	188	5	CID000443871
Drug	Chlorocruorin	C3 HBG1 HBG2 HBZ	4.97e-05	25	188	4	CID005748247
Drug	AC1Q5TZX	GANC ABCC9 HBG1 HBG2 HBZ	5.17e-05	49	188	5	CID000004547
Drug	nectrisine	GANC GBA3 FUCA1	6.37e-05	10	188	3	CID000122106
Drug	NSC-107146	DHFR DHFR2	6.78e-05	2	188	2	CID000267616
Drug	gamma-tBAMT	DHFR DHFR2	6.78e-05	2	188	2	CID000125341
Drug	aditoprim	DHFR DHFR2	6.78e-05	2	188	2	CID000068755
Drug	2,4-diamino-5-benzylpyrimidine	DHFR DHFR2	6.78e-05	2	188	2	CID000081752
Drug	methotrexate-alpha-aspartate	DHFR DHFR2	6.78e-05	2	188	2	CID000100376
Drug	ethyl isocyanatoacetate	DHFR DHFR2	6.78e-05	2	188	2	CID000076283
Drug	3'-fluoroaminopterin	DHFR DHFR2	6.78e-05	2	188	2	CID000128780
Drug	DIVEMA-MTX	DHFR DHFR2	6.78e-05	2	188	2	CID000430857
Drug	4-ethylacetophenone	DHFR DHFR2	6.78e-05	2	188	2	CID000013642
Drug	2,4-diamino-5-phenylpyrimidine	DHFR DHFR2	6.78e-05	2	188	2	CID000134761
Drug	terbacil	ACACA GBA3	6.78e-05	2	188	2	CID000022188
Drug	AC1L1CH3	HNMT HBG1 HBG2 TAP1 HBZ KPNA2	7.45e-05	85	188	6	CID000001896
Drug	glimepiride	GANC ABCC9 HBG1 HBG2 HBZ	8.29e-05	54	188	5	CID000003476
Drug	1q65	ACACA QTRT2 HBG1 HBG2 HBZ	8.29e-05	54	188	5	CID000448017
Drug	FMTX	SPTBN1 DHFR DHFR2	8.71e-05	11	188	3	CID000125843
Drug	syntometrine	HBG1 HBG2 HBZ	8.71e-05	11	188	3	CID011979741
Drug	NFPLP	HBG1 HBG2 HBZ	8.71e-05	11	188	3	CID006451852
Drug	N-(2-hydroxypropyl)valine	HBG1 HBG2 HBZ	8.71e-05	11	188	3	CID000130204
Drug	dimethyl adipimidate	SPTBN1 HBG1 HBG2 HBZ	1.04e-04	30	188	4	CID000025738
Drug	Ferastral	HBG1 HBG2 HBZ	1.15e-04	12	188	3	CID000171553
Drug	2-hydroxylamino-5-ethyl-5-propylbarbituric acid	HBG1 HBG2 HBZ	1.15e-04	12	188	3	CID000128182
Drug	7-methylguanosine 5'-phosphate	HBG1 HBG2 HBZ	1.15e-04	12	188	3	CID000440190
Disease	autism spectrum disorder (implicated_via_orthology)	TMPRSS9 RIMS3 ARID1B PKP1 SYN1 SYN2 CTNND1	4.15e-05	152	179	7	DOID:0060041 (implicated_via_orthology)
Disease	Hemoglobin F Disease	CACNA1H HBG1 HBG2	9.47e-05	15	179	3	C0019025
Disease	FETAL HEMOGLOBIN QUANTITATIVE TRAIT LOCUS 1	HBG1 HBG2	1.09e-04	3	179	2	141749
Disease	Hereditary persistence of fetal hemoglobin	HBG1 HBG2	1.09e-04	3	179	2	cv:C0019025
Disease	delta beta-thalassemia (is_implicated_in)	HBG1 HBG2	1.09e-04	3	179	2	DOID:0080773 (is_implicated_in)
Disease	sickle cell anemia (is_implicated_in)	APOB C3 HBG2	1.16e-04	16	179	3	DOID:10923 (is_implicated_in)
Disease	neck circumference	USP44 ADAMTS20 PDZRN3	1.98e-04	19	179	3	EFO_0011043
Disease	FETAL HEMOGLOBIN QUANTITATIVE TRAIT LOCUS 1	HBG1 HBG2	2.18e-04	4	179	2	C1841621
Disease	asthma (is_implicated_in)	HNMT NOD1 CLCA1 TLR3 C3 TAP1	4.06e-04	157	179	6	DOID:2841 (is_implicated_in)
Disease	hematocrit	ZYG11A HIVEP2 ACACA LYPLAL1 DNAH2 APOB CDK10 AP4E1 FAT1 ARID1B ALDH1A2 SYN2 ACTL6B HBG1 HBG2 PSD4	4.66e-04	1011	179	16	EFO_0004348
Disease	response to antipsychotic drug	STXBP5L SLC26A9 EYS TENM4	4.90e-04	60	179	4	GO_0097332
Disease	v-set and transmembrane domain-containing protein 4 measurement	MED16 C3	5.40e-04	6	179	2	EFO_0803247
Disease	pathological myopia	SPTBN1 RNF135 ALDH1A2 PTPRD DNAH9	5.92e-04	111	179	5	EFO_0004207
Disease	lipoprotein A measurement	SERPINE3 APOB ARID1B ALDH1A2 GPCPD1	6.17e-04	112	179	5	EFO_0006925
Disease	LDL cholesterol change measurement	APOB PKD1L3	7.53e-04	7	179	2	EFO_0007804
Disease	regulator of G-protein signaling 8 measurement	MED16 C3	7.53e-04	7	179	2	EFO_0801997
Disease	esterified cholesterol measurement, intermediate density lipoprotein measurement	APOB ALDH1A2	1.00e-03	8	179	2	EFO_0008589, EFO_0008595
Disease	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 measurement	MED16 C3	1.00e-03	8	179	2	EFO_0801373
Disease	calcium/calmodulin-dependent protein kinase type 1D measurement	MED16 C3	1.00e-03	8	179	2	EFO_0008063
Disease	Schizophrenia	RIMS3 SLC30A3 LPAR1 NDUFS1 TRAK1 ALDH1A2 TENM4 TLR3 SYN1 SYN2 BRD1 TAP1 PCNT PMP2	1.04e-03	883	179	14	C0036341
Disease	alcohol use disorder (implicated_via_orthology)	ARID1B CLIC2 RBPJ KCNMA1 ACTL6B PSD4	1.26e-03	195	179	6	DOID:1574 (implicated_via_orthology)
Disease	Colorectal Carcinoma	ACACA SRC APOB LPAR1 MFN1 FAT1 PTPRD ABCA5 CD226 DHFR SCNN1B PZP	1.26e-03	702	179	12	C0009402
Disease	cellular retinoic acid-binding protein 1 measurement	MED16 C3	1.28e-03	9	179	2	EFO_0801463
Disease	gout	FSTL4 ABCC9 MFN1 FAT1 ALDH1A2 PTPRD	1.29e-03	196	179	6	EFO_0004274
Disease	Growth Disorders	RNF135 LPAR1 KCNMA1	1.35e-03	36	179	3	C0018273
Disease	small cell lung carcinoma	FSTL4 NEU1 ALDH1A2 RGS6	1.45e-03	80	179	4	EFO_0000702
Disease	Colorectal Neoplasms	SRC LPAR1 FAT1 PTPRD ABCA5 CD226 DHFR	1.57e-03	277	179	7	C0009404
Disease	cup-to-disc ratio measurement, optic cup area measurement, optic disc area measurement	SERPINE3 EPB41L3	1.59e-03	10	179	2	EFO_0006937, EFO_0006939, EFO_0006940
Disease	thiamine measurement	ANO5 LPAR1	1.59e-03	10	179	2	EFO_0010540
Disease	body weight	PAPPA2 MMS22L HIVEP2 E2F7 ANO5 HUWE1 HMCES CDK10 EYS ALDH1A2 ASXL3 CDC16 TLL1 CHFR POLN NIPBL EPHA4	1.80e-03	1261	179	17	EFO_0004338
Disease	attention deficit hyperactivity disorder, conduct disorder	FSTL4 PKD1L3 PTPRD	1.84e-03	40	179	3	EFO_0003888, EFO_0004216
Disease	brain measurement, neuroimaging measurement	SPTBN1 RNF135 LPAR1 ALDH1A2 DHFR CARF ADAMTS20 MACF1 WDR12 EPHA4	2.04e-03	550	179	10	EFO_0004346, EFO_0004464
Disease	oncostatin-M measurement	MED16 C3	2.32e-03	12	179	2	EFO_0010792
Disease	tyrosine-protein kinase ZAP-70 measurement	MED16 C3	2.32e-03	12	179	2	EFO_0020833
Disease	Thromboembolism	FAM135B HBG1 HBG2	2.42e-03	44	179	3	HP_0001907
Disease	colon carcinoma (is_marker_for)	SRC TLR3	2.73e-03	13	179	2	DOID:1520 (is_marker_for)
Disease	rhinitis (biomarker_via_orthology)	MFN1 C3	2.73e-03	13	179	2	DOID:4483 (biomarker_via_orthology)
Disease	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	PAPPA2 ARHGEF17	3.17e-03	14	179	2	EFO_0004307, EFO_0008464
Disease	antibody measurement	RGS6 PTPRD ASXL3	3.30e-03	49	179	3	EFO_0004556
Disease	neurotic disorder	TMPRSS9 MMS22L FAM135B ASXL3	3.38e-03	101	179	4	EFO_0004257
Disease	gastroesophageal reflux disease	MMS22L HIVEP2 SLC6A15 APOB	3.38e-03	101	179	4	EFO_0003948
Disease	cholesteryl esters to total lipids in IDL percentage	APOB ALDH1A2 MACF1	3.49e-03	50	179	3	EFO_0022247
Disease	peak expiratory flow	PAPPA2 CAPZB SLC26A9 ARHGEF17 EYS SLC15A1 MICAL3 BRD1 PDZRN3	3.51e-03	498	179	9	EFO_0009718
Disease	low density lipoprotein triglyceride measurement	APOB ALDH1A2	3.65e-03	15	179	2	EFO_0009946
Disease	lysophosphatidylethanolamine 18:0 measurement	ALDH1A2 TNR	3.65e-03	15	179	2	EFO_0010367
Disease	triglycerides to total lipids in chylomicrons and extremely large VLDL percentage	APOB ALDH1A2	3.65e-03	15	179	2	EFO_0022328
Disease	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	APOB SLC30A3 ALDH1A2	3.69e-03	51	179	3	EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Disease	Spermatogenic Failure, Nonobstructive, Y-Linked	CDY1 CDY2A	4.15e-03	16	179	2	C1839071
Disease	Spermatogenic failure, Y-linked, 2	CDY1 CDY2A	4.15e-03	16	179	2	cv:C1839071
Disease	SPERMATOGENIC FAILURE, Y-LINKED, 2	CDY1 CDY2A	4.15e-03	16	179	2	415000
Disease	phosphatidylethanolamine measurement	DIABLO ABCC9 APOB ALDH1A2 PTPRH	4.17e-03	173	179	5	EFO_0010228
Disease	body mass index, osteoarthritis	CARF WDR12 CACNA1H	4.34e-03	54	179	3	EFO_0004340, MONDO_0005178
Disease	Early Pregnancy Loss	CD226 DHFR FLRT3 TNR	4.44e-03	109	179	4	C3830362
Disease	Spontaneous abortion	CD226 DHFR FLRT3 TNR	4.44e-03	109	179	4	C0000786
Disease	Miscarriage	CD226 DHFR FLRT3 TNR	4.44e-03	109	179	4	C4552766
Disease	Abortion, Tubal	CD226 DHFR FLRT3 TNR	4.44e-03	109	179	4	C0000822
Disease	retinopathy	SRC TENM4	4.69e-03	17	179	2	EFO_0003839
Disease	level of Sphingomyelin (d32:1) in blood serum	ALDH1A2 KCNH5	4.69e-03	17	179	2	OBA_2045173
Disease	cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	APOB ALDH1A2	4.69e-03	17	179	2	EFO_0022232
Disease	ischemia (implicated_via_orthology)	ARID1B SCNN1B	4.69e-03	17	179	2	DOID:326 (implicated_via_orthology)
Disease	pneumonia, COVID-19	ACACA RGS22 SLC6A15 FAT1	5.05e-03	113	179	4	EFO_0003106, MONDO_0100096
Disease	very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	APOB ALDH1A2	5.25e-03	18	179	2	EFO_0008317, EFO_0008589
Disease	urate measurement, spine bone mineral density	PAPPA2 SRC PTPRD	5.30e-03	58	179	3	EFO_0004531, EFO_0007701
Disease	trait in response to apixaban	MROH5 TENM4 SLC15A4 C3	5.37e-03	115	179	4	OBA_2050328
Disease	cholesterol to total lipids in IDL percentage	APOB ALDH1A2 MACF1	5.83e-03	60	179	3	EFO_0022233
Disease	primary ciliary dyskinesia (implicated_via_orthology)	DPCD DAW1	5.85e-03	19	179	2	DOID:9562 (implicated_via_orthology)
Disease	hydrocephalus (implicated_via_orthology)	DPCD AK7	5.85e-03	19	179	2	DOID:10908 (implicated_via_orthology)
Disease	sodium-coupled monocarboxylate transporter 1 measurement	APOB ALDH1A2	5.85e-03	19	179	2	EFO_0802076
Disease	cancer (implicated_via_orthology)	SRC ARID1B DHFR DHFR2 MACF1 NIPBL	6.04e-03	268	179	6	DOID:162 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LSETKAALVSTMSLW	ABCA5	826	Q8WWZ7
KSDICNTMSLWISGT	FAM227A	271	F5H4B4
WTGAQMTGVTRKNIS	ERVPABLB-1	121	P60509
RIAAEVGQSSMWIST	BRD1	906	O95696
LKLASWTSMALAASG	ADCK1	6	Q86TW2
LRKIWSSAQGIESML	CDY1	516	Q9Y6F8
VLRKIWSSAQGIESM	CDY2A	516	Q9Y6F7
LSGATVTLWMSLVVT	ANO5	461	Q75V66
KALTVSSAMQAGTVW	ALDH1A2	456	O94788
ILASLGTFQQMWISK	ACTL6B	396	O94805
MISAAWSIFLIGTKI	FLRT3	1	Q9NZU0
KDSITTWEILAVSMS	C3	796	P01024
AMWALGDKIASSIVA	ACACA	236	Q13085
LVTSLTVEWMGLTAA	ABCC9	1051	O60706
MLLAAASTDGKVWIL	AASDH	1036	Q4L235
MSLKSGLLAESTWAL	ARID1B	1711	Q8NFD5
LKLETTWMTAVGLSE	DIABLO	151	Q9NR28
STVMLWLQTNKSGSG	CAPZB	171	P47756
LQVGLWKSQASTHEM	EFCC1	231	Q9HA90
METTKRLSWPQSTGI	ASXL3	2061	Q9C0F0
TGMKISSTAKWLTQG	ADAMTS20	1856	P59510
LMNDSVSSETKAWLI	AP4E1	541	Q9UPM8
SKTWGKSTETMEVIN	POLN	36	Q7Z5Q5
LSSKTADVTKVWGMG	RCC1L	121	Q96I51
SGDLTSATNIVKWIM	PZP	1231	P20742
NWMTIQELLTHGTKS	PDZRN3	1036	Q9UPQ7
TGTDIVQWLMKNLSI	RGS6	61	P49758
KTSVAVEMAGAPSWT	IQCN	621	Q9H0B3
MVTSGVQSKAVSDWL	NCLN	186	Q969V3
SGKSSVINAMLWDKV	MFN1	86	Q8IWA4
MVDSSLGVWVTLKGS	ARHGEF17	1866	Q96PE2
SWAAMKGNLESVSIL	ASB8	156	Q9H765
AINMETGWITTLKEL	FAT1	2861	Q14517
SNARIVKWSDGSMSL	LEO1	436	Q8WVC0
GGLLSVKMENSWVQS	KRBA1	326	A5PL33
AGVNVTDLTMSWKSG	MICAL3	536	Q7RTP6
MWVGTQTSQVEIKLS	FLII	1206	Q13045
WQKMTIAGTTDTPTD	GPD2	346	P43304
KGMHTVNSKWLSVGT	EYS	131	Q5T1H1
NFSTTKTEGLIVWMG	EYS	3006	Q5T1H1
SVKDWAGVMISAQTL	KCNMA1	161	Q12791
LDGWSVVQTMVVSTK	GTPBP6	131	O43824
KMKNLVWTSGISALD	EIF3L	496	Q9Y262
MGILVKSWAQIFATS	MMS22L	946	Q6ZRQ5
STWSMSKGIDTEKVL	KCNH5	511	Q8NCM2
TVRAVWTMGDIKTSV	KATNB1	511	Q9BVA0
LATEWNTVSKLVMGL	LPAR1	41	Q92633
WTTDSGNILKETMTV	CARF	501	Q8N187
LITVSTDGKMCSWSL	DYNC1I1	406	O14576
SAVVSVGDWLQAIKM	EPHA4	911	P54764
AKMLIIVVSGSSGWD	HNMT	166	P50135
SSGVIKDIWTKMADT	KIAA0232	821	Q92628
AWISSTVTPKMLVNF	OR5H2	76	Q8NGV7
IWSTMQVKITSPGLF	NEMP2	66	A6NFY4
ITMLGIQGDLKWSTD	FUCA1	421	P04066
IKTTVGKSTGWMTES	GANC	781	Q8TET4
RVVQKTSSGFSVQWM	NIPBL	2726	Q6KC79
LVATGSMDTTAKLWD	DAW1	191	Q8N136
ISTVLTEAAMKVRWN	HEATR6	961	Q6AI08
LAVKNSKSISEVGMW	NOD1	806	Q9Y239
VAVNVILLLSMGWTS	MANSC4	6	A6NHS7
SLGSTVQSHTKGIWM	GBP1	66	P32455
SLGSTVKSHTKGIWM	GBP2	66	P32456
SLGSTVKSHTKGIWM	GBP3	66	Q9H0R5
DTKTVSEWISQMATL	HUWE1	1506	Q7Z6Z7
VNDWTSSNEKAVMSL	PCNT	3001	O95613
KWMLEGQVDSLSVTL	ITFG2	176	Q969R8
SGDMSAKEKLLLWTQ	MACF1	191	Q9UPN3
LGVSSSTDGTMKIWQ	PAAF1	106	Q9BRP4
LATSQALDTVWRMAK	OTULINL	31	Q9NUU6
LKAMQLSWTSLALVG	MED16	431	Q9Y2X0
MTKNQTWVTEFILLG	OR2A5	1	Q96R48
IQKEATWTMSNITAG	KPNA2	351	P52292
SWSRVMVDSKATLGL	NPC1L1	656	Q9UHC9
VSMGTVLKTSSWNLD	PARP14	1071	Q460N5
MVIGQTNKSLTIHWL	PAPPA2	851	Q9BXP8
KSVSVWSVAGRVEMT	QTRT2	111	Q9H974
IVSMWAKISTQADTI	HBZ	11	P02008
IVAMSSWLQKASGSL	APOB	1231	P04114
WEMSQSSIKSSICLL	CDC16	121	Q13042
TRGLTWKNMLTESLV	CHFR	566	Q96EP1
KSTVVWMLEALEGLS	ESPL1	431	Q14674
SPVSTNASWLKILEM	CD101	716	Q93033
TGESMLWKATIVLSR	GPCPD1	46	Q9NPB8
WTPTANLKMLISAAS	E2F7	81	Q96AV8
VLQTSWAKGRMTTRT	C6orf141	171	Q5SZD1
QKGMVSLSLFAVWLE	GBA3	216	Q9H227
GIVSWDMVSITFIKQ	ELMO2	161	Q96JJ3
LGTTTQTTSIDMWAV	CDK10	211	Q15131
TSWLAEMTSSVISVK	CXADR	186	P78310
MAVTGWLESLRTAQK	DPCD	1	Q9BVM2
LANKVDMVWIVGGSS	DHFR	106	P00374
RITWLKNGVDVSTQM	FSTL4	371	Q6MZW2
EVQASWQKMVTAVAS	HBG1	126	P69891
WQKMVTAVASALSSR	HBG1	131	P69891
IMQTALLKGNSVDSW	HEATR4	566	Q86WZ0
IVIWGDMNLTASKAN	HYAL4	336	Q2M3T9
LQQQLWSKSCEMTGV	DHRSX	311	Q8N5I4
SRLSTIWKGFINMQS	DIDO1	1051	Q9BTC0
ISAVAQAIMSKLWLG	GGT5	496	P36269
VSSSQIWLETTMAKV	CCHCR1	436	Q8TD31
SSAIGFLMKNSWQIT	CEMIP2	896	Q9UHN6
LSSLWGKLASEILMQ	EIF3E	166	P60228
TAQLLVLLMSWEGTT	MARF1	1416	Q9Y4F3
WAEETNSMLKSLGVT	LYPLAL1	186	Q5VWZ2
LANKVDMIWIVGGSS	DHFR2	106	Q86XF0
QLKELWDTIGMVTSS	DNAH9	1301	Q9NYC9
NNSTLVSTGLWLMQK	FAM135B	1256	Q49AJ0
KQIGVSVDTWLKSAM	FCHSD2	396	O94868
SMGILTQVEWFKIGT	CD226	41	Q15762
EVQASWQKMVTGVAS	HBG2	126	P69892
WQKMVTGVASALSSR	HBG2	131	P69892
SLFVLSSKDGWVNIM	CACNA1H	1496	O95180
LSTNEWTDGILSSVM	DNAH2	2136	Q9P225
LLVSSDMKSWSTVLA	SLC22A7	421	Q9Y694
KSSGLSTWIGNQMLS	SLC13A4	481	Q9UKG4
GSRWTLQATTMSGKI	SLC15A1	301	P46059
LLALVSIKAIGWMSS	SLC15A4	506	Q8N697
IAQGLSSESWSIMKN	SCAP	381	Q12770
SWEVSVSLSVGFKTM	SCNN1B	76	P51168
MDLTEVITGTLWNLS	CTNND1	466	O60716
SWVQKMETKTESSGI	EPB41L3	821	Q9Y2J2
SGSSQRMLQWLATKS	HMCES	281	Q96FZ2
WLKGVKFNVTTVDMT	CLIC2	41	O15247
SQKGASSTWMKAIVS	CEBPZ	226	Q03701
WMKHNVADSQITTIG	PTPRD	466	P23468
MNLPSTKVSWAAVTL	HCRT	1	O43612
GNTIIVTAIWMDSTR	OR52I2	71	Q8NH67
MAIKSVPFLSTDVWS	MROH5	251	Q6ZUA9
SMEWDTQVVKGSSPL	OIP5	36	O43482
LLLSDMWSSKELQGV	PKP1	706	Q13835
VSGNWKTNTGSAMLE	SYN1	331	P17600
ISGNWKTNTGSAMLE	SYN2	331	Q92777
QLSAWHMVKETVLGS	RNF135	356	Q8IUD6
MGTWNGTTRVAIKTL	SRC	286	P12931
SSISESGGLNWKMTI	SLC6A15	216	Q9H2J7
MAFVKSGWLLRQSTI	PLEKHB2	1	Q96CS7
TLWMKFVSDGTVNKA	TLL1	551	O43897
WLSLITLMATTFGQK	TMEM185A	251	Q8NFB2
VVSQWKDMIGTAFSL	SLC26A9	326	Q7LBE3
WLKMTNSTVSDVLCI	LGI2	181	Q8N0V4
ISEWMATGKSTAFQL	NDUFAF7	106	Q7L592
LTAWVSSLSMGITLI	SLC16A14	71	Q7RTX9
IAQKIRMTSGVTGDW	NDUFS1	496	P28331
LVSQVRWSKSGMNFT	RGS22	146	Q8NE09
AKMVAIVGLTQWSKS	RIMS3	51	Q9UJD0
NLGMWKASITSGEVT	SNX25	506	Q9H3E2
CLAKIANSMVSTWTG	TAF2	701	Q6P1X5
VQVAKATGKMWSTAT	HMGB4	121	Q8WW32
SSAVLMESLKSIWSS	SMG7	1091	Q92540
VASTMLVWSKDDGVS	NEU1	166	Q99519
TAKEMSSWIARINLA	PSD4	876	Q8NDX1
SLELSKDQATSWMIS	PKD1L3	1176	Q7Z443
KDQATSWMISIILSV	PKD1L3	1181	Q7Z443
LSERSLSWISQGMSV	SLC5A8	376	Q8N695
NSWTTSISGMLLKVG	TAP1	411	Q03518
SDLTGTSMWVLVKVS	PGAP1	341	Q75T13
EGKNISTVLWETMLL	MROH2B	561	Q7Z745
EMSGKIAKSHNTIWS	SLC25A2	141	Q9BXI2
ATVSRMKLQVWGTLT	SCARF1	461	Q14162
MKLQVWGTLTSLGST	SCARF1	466	Q14162
QKVAWFLQITMGTTA	SLC28A2	286	O43868
GSIKFWDASAITLQM	STXBP5L	471	Q9Y2K9
TGLHKMWEVLESTTQ	SPTBN1	1356	Q01082
DTKTVTVNMTAWTII	TGM3	511	Q08188
KMQDLGVISSISLSW	TBC1D9B	656	Q66K14
TVGKDTLFLITWTMQ	CLCA1	511	A8K7I4
TTTMSTSLGLVWLLK	TRAK1	731	Q9UPV9
WKDVTSALSLANMVL	TMEM269	31	A0A1B0GVZ9
TTFLGLKWTNLTMLD	TLR3	266	O15455
WQEMTSTGALKSLSL	ZSCAN30	146	Q86W11
SQGAKWVDTQVVLAM	PYGM	211	P11217
SASSDGTVKIWNMKT	SMU1	366	Q2TAY7
TISNVTKDSVMVSWS	TNR	871	Q92752
KSMQALSTVPLDWVT	TMPRSS9	471	Q7Z410
WVTMGTNSALKSVTT	TENM4	1651	Q6N022
LVLVSTMSFQGTWRK	SERPINE3	186	A8MV23
GVDEWLTTTKMTKHQ	REP15	71	Q6BDI9
MSLSSLLKVVTASLW	TRAV14DV4	1	A0A0A6YYC5
MINDGASWTIISTDK	RBPJ	321	Q06330
SETLGALASVVSLWM	SLC30A3	141	Q99726
KLMSTSNTWCDLGIN	TTC37	771	Q6PGP7
IATTKLMNGTSWIEA	VPS33A	576	Q96AX1
WSLEGKSIMTIVGHT	WDR12	126	Q9GZL7
SMFVKTSTPAEWIAQ	TRANK1	1691	O15050
GKLTSSSAWKQFTQM	HIVEP2	1716	P31629
ITTIWDGMKVVSHSV	PTPRH	731	Q9HD43
VMTWQGKLTDRTASI	ZYG11A	81	Q6WRX3
IVLSDRSQAVAWMKS	WDR87	36	Q6ZQQ6
LNQWLAMTASEKTRS	USP44	306	Q9H0E7
SSVTGNALWKAMEKS	TERF2IP	156	Q9NYB0
GRKSTGSWVTQMENL	nan	36	Q8TCH9
MAVFKTTLWRLISGT	KLRD1	1	Q13241
LLSTVMTWARSKALD	AK7	151	Q96M32
MSNKFLGTWKLVSSE	PMP2	1	P02689
TLGEVWVQKTSEMNT	NMD3	341	Q96D46