Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionGTPase activator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D OCRL ARHGAP35 TBC1D3C TBC1D3B IQGAP1 TBC1D3I TBC1D3G PLXNB1 RASAL2 TBC1D3K TBC1D3F

1.39e-1027914116GO:0005096
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D OCRL ARHGAP35 TBC1D3C TBC1D3B IQGAP1 FGD1 TBC1D3I DNMBP TBC1D3G VAV2 PLXNB1 RASAL2 TBC1D3K TBC1D3F

3.15e-0950714119GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D OCRL ARHGAP35 TBC1D3C TBC1D3B IQGAP1 FGD1 TBC1D3I DNMBP TBC1D3G VAV2 PLXNB1 RASAL2 TBC1D3K TBC1D3F

3.15e-0950714119GO:0030695
GeneOntologyMolecularFunctionenzyme activator activity

TBC1D3E TBC1D3 ERCC6 TBC1D3H TBC1D3L TBC1D3D OCRL ARHGAP35 TBC1D3C TBC1D3B PPP4R3A IQGAP1 RING1 PRKCE PRKAG2 TBC1D3I TBC1D3G PLXNB1 RASAL2 TBC1D3K TBC1D3F

7.09e-0965614121GO:0008047
GeneOntologyMolecularFunctionenzyme regulator activity

TBC1D3E TBC1D3 ERCC6 TBC1D3H TBC1D3L TBC1D3D OCRL ARHGAP35 TBC1D3C TBC1D3B PPP4R3A IQGAP1 RING1 KIDINS220 FGD1 PRKCE PARP9 PRKAG2 TBC1D3I CABIN1 DNMBP TBC1D3G VAV2 PLXNB1 RASAL2 TBC1D3K TBC1D3F

1.94e-06141814127GO:0030234
GeneOntologyMolecularFunctionmolecular function activator activity

TBC1D3E TBC1D3 ERCC6 TBC1D3H TBC1D3L TBC1D3D OCRL ARHGAP35 GDF9 TBC1D3C TBC1D3B PPP4R3A IQGAP1 RING1 PRKCE PRKAG2 TBC1D3I TBC1D3G PLXNB1 RASAL2 TBC1D3K TBC1D3F

5.30e-05123314122GO:0140677
GeneOntologyMolecularFunctionsemaphorin receptor activity

PLXNA1 PLXNB1 PLXNB3

7.24e-05121413GO:0017154
GeneOntologyMolecularFunctionsmall conductance calcium-activated potassium channel activity

KCNN1 KCNN3

2.94e-0441412GO:0016286
GeneOntologyMolecularFunctionGTPase activating protein binding

ARHGAP35 FMNL1 PLXNB1

3.07e-04191413GO:0032794
GeneOntologyBiologicalProcessregulation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B IQGAP1 FGD1 TBC1D3I TBC1D3G PLXNA1 VAV2 PLXNB1 PLXNB3 TBC1D3K TBC1D3F

2.04e-1033514417GO:0043087
GeneOntologyBiologicalProcessactivation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

2.79e-1010914411GO:0090630
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G PLXNB1 TBC1D3K TBC1D3F

1.50e-0724414412GO:0043547
GeneOntologyBiologicalProcessregulation of cell shape

ARHGAP35 ATP10A FGD1 DNMBP KIT FMNL1 PLXNA1 PLXNB1 PLXNB3

1.79e-061591449GO:0008360
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

SETX HAP1 ARHGAP35 IQGAP1 PTPN5 FBXO38 KIDINS220 LRP1 MACF1 KIT STK24 PLXNA1 PLXNB1 PLXNB3 HTT

1.99e-0649414415GO:0031346
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

DCDC2 TBC1D3 HAP1 OCRL ARHGAP35 CNTROB CC2D2B NISCH WDR35 FGD1 DNMBP KIT HYDIN VAV2 PLXNB3 HTT CFAP46

4.55e-0667014417GO:0120031
GeneOntologyBiologicalProcesscell projection assembly

DCDC2 TBC1D3 HAP1 OCRL ARHGAP35 CNTROB CC2D2B NISCH WDR35 FGD1 DNMBP KIT HYDIN VAV2 PLXNB3 HTT CFAP46

6.09e-0668514417GO:0030031
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

DCDC2 SETX TBC1D3 HAP1 ARHGAP35 CNTROB IQGAP1 PTPN5 FBXO38 KIDINS220 LRP1 MACF1 KIT ULK2 STK24 PLXNA1 PLXNB1 PLXNB3 HTT

7.00e-0684614419GO:0120035
GeneOntologyBiologicalProcessregulation of cell projection organization

DCDC2 SETX TBC1D3 HAP1 ARHGAP35 CNTROB IQGAP1 PTPN5 FBXO38 KIDINS220 LRP1 MACF1 KIT ULK2 STK24 PLXNA1 PLXNB1 PLXNB3 HTT

9.27e-0686314419GO:0031344
GeneOntologyBiologicalProcesspositive regulation of neuron projection development

SETX HAP1 ARHGAP35 IQGAP1 PTPN5 FBXO38 KIDINS220 LRP1 STK24 PLXNB3

1.02e-0524914410GO:0010976
GeneOntologyBiologicalProcessregulation of hydrolase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B IQGAP1 LRP1 FGD1 TBC1D3I TBC1D3G PLXNA1 VAV2 PLXNB1 PLXNB3 HTT TBC1D3K TBC1D3F

1.18e-0587814419GO:0051336
GeneOntologyBiologicalProcesscilium assembly

DCDC2 TBC1D3 HAP1 OCRL ARHGAP35 CNTROB CC2D2B NISCH WDR35 DNMBP HYDIN HTT CFAP46

1.46e-0544414413GO:0060271
GeneOntologyBiologicalProcesscilium organization

DCDC2 TBC1D3 HAP1 OCRL ARHGAP35 CNTROB CC2D2B NISCH WDR35 DNMBP HYDIN HTT CFAP46

3.02e-0547614413GO:0044782
GeneOntologyBiologicalProcesspositive regulation of molecular function

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D HAP1 TBC1D3C TBC1D3B SIRT3 MAP3K4 IQGAP1 LRP1 IRAK3 STK39 PARP9 GNAL PRKAG2 TBC1D3I KIT TBC1D3G PLXNB1 HTT TBC1D3K TBC1D3F

5.24e-05143014424GO:0044093
GeneOntologyBiologicalProcessregulation of cell morphogenesis

ARHGAP35 ATP10A FGD1 MACF1 DNMBP KIT FMNL1 PLXNA1 PLXNB1 PLXNB3

5.32e-0530214410GO:0022604
GeneOntologyBiologicalProcessregulation of neuron projection development

SETX HAP1 ARHGAP35 IQGAP1 PTPN5 FBXO38 KIDINS220 LRP1 MACF1 ULK2 STK24 PLXNA1 PLXNB1 PLXNB3

1.01e-0461214414GO:0010975
GeneOntologyBiologicalProcessregulation of cilium assembly

DCDC2 TBC1D3 HAP1 ARHGAP35 CNTROB HTT

1.11e-041081446GO:1902017
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

SETX HAP1 ARHGAP35 ATP10A MAP3K4 IQGAP1 PTPN5 FBXO38 KIDINS220 LRRTM2 WDR35 LRP1 LRP2 MACF1 PRKCE KIT CNOT1 STK24 PLXNA1 PLXNB1 PLXNB3 HTT

2.01e-04136614422GO:0051130
GeneOntologyBiologicalProcesspositive regulation of hydrolase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G PLXNB1 TBC1D3K TBC1D3F

2.03e-0449914412GO:0051345
GeneOntologyBiologicalProcessvisual learning

DCDC2 HRH1 TANC1 KIT HTT

2.17e-04781445GO:0008542
GeneOntologyBiologicalProcesspositive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

HAP1 HTT

2.88e-0441442GO:0031587
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B SIRT3 MAP3K4 IQGAP1 GNAL PRKAG2 TBC1D3I KIT TBC1D3G PLXNB1 TBC1D3K TBC1D3F

2.99e-04102814418GO:0043085
GeneOntologyBiologicalProcessvisual behavior

DCDC2 HRH1 TANC1 KIT HTT

3.42e-04861445GO:0007632
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection assembly

DCDC2 TBC1D3 HAP1 ARHGAP35 CNTROB KIT PLXNB3 HTT

3.60e-042481448GO:0120032
GeneOntologyBiologicalProcessregulation of cell projection assembly

DCDC2 TBC1D3 HAP1 ARHGAP35 CNTROB KIT PLXNB3 HTT

3.90e-042511448GO:0060491
GeneOntologyBiologicalProcessregulation of axonogenesis

ARHGAP35 LRP1 MACF1 ULK2 PLXNA1 PLXNB1 PLXNB3

4.08e-041921447GO:0050770
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LRP1 LRP2

4.77e-0451442GO:1905167
GeneOntologyBiologicalProcessendonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

TBL3 UTP20

4.77e-0451442GO:0000472
GeneOntologyBiologicalProcessrRNA 5'-end processing

TBL3 UTP20

4.77e-0451442GO:0000967
GeneOntologyBiologicalProcesspositive regulation of lipophagy

SPTLC2 HTT

4.77e-0451442GO:1904504
GeneOntologyBiologicalProcessregulation of lipophagy

SPTLC2 HTT

4.77e-0451442GO:1904502
GeneOntologyBiologicalProcesschemoattraction of axon

LRP1 LRP2

4.77e-0451442GO:0061642
GeneOntologyCellularComponentsemaphorin receptor complex

PLXNA1 PLXNB1 PLXNB3

8.70e-05131443GO:0002116
DomainTBC

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

2.24e-124913810SM00164
DomainRabGAP-TBC

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

5.19e-125313810PF00566
DomainRab-GTPase-TBC_dom

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

7.69e-125513810IPR000195
DomainTBC_RABGAP

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

7.69e-125513810PS50086
DomainRho_GTPase_activation_prot

OCRL ARHGAP35 IQGAP1 PLXNA1 PLXNB1 PLXNB3 RASAL2

3.98e-06881387IPR008936
DomainPlexin_cytopl

PLXNA1 PLXNB1 PLXNB3

3.21e-0591383PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA1 PLXNB1 PLXNB3

3.21e-0591383IPR013548
DomainPlexin

PLXNA1 PLXNB1 PLXNB3

3.21e-0591383IPR031148
DomainRasGAP_dom

IQGAP1 PLXNB1 RASAL2

2.97e-04181383IPR001936
DomainCaMBD

KCNN1 KCNN3

3.22e-0441382PF02888
DomainCaM-bd_dom

KCNN1 KCNN3

3.22e-0441382IPR004178
DomainCaMBD

KCNN1 KCNN3

3.22e-0441382SM01053
DomainK_chnl_Ca-activ_SK

KCNN1 KCNN3

3.22e-0441382IPR015449
DomainSK_channel

KCNN1 KCNN3

3.22e-0441382PF03530
DomainARM-type_fold

NBEA RYR3 PPP4R3A AP4E1 MROH8 UTP20 FMNL1 EIF3M HTT

9.49e-043391389IPR016024
DomainIPT

PLXNA1 PLXNB1 PLXNB3

1.01e-03271383SM00429
DomainCH

IQGAP1 CLMN MACF1 VAV2

1.36e-03651384SM00033
DomainSemap_dom

PLXNA1 PLXNB1 PLXNB3

1.52e-03311383IPR001627
DomainSEMA

PLXNA1 PLXNB1 PLXNB3

1.52e-03311383PS51004
DomainTIG

PLXNA1 PLXNB1 PLXNB3

1.52e-03311383PF01833
DomainSema

PLXNA1 PLXNB1 PLXNB3

1.52e-03311383SM00630
DomainSema

PLXNA1 PLXNB1 PLXNB3

1.52e-03311383PF01403
DomainIPT

PLXNA1 PLXNB1 PLXNB3

1.67e-03321383IPR002909
DomainPlexin_repeat

PLXNA1 PLXNB1 PLXNB3

1.67e-03321383IPR002165
DomainPSI

PLXNA1 PLXNB1 PLXNB3

1.67e-03321383PF01437
DomainTPR-like_helical_dom

TTC34 TTC7B WDR35 TANC1 SEL1L2 CABIN1 CFAP46

1.75e-032331387IPR011990
DomainCH

IQGAP1 CLMN MACF1 VAV2

1.79e-03701384PF00307
Domain-

IQGAP1 CLMN MACF1 VAV2

1.89e-037113841.10.418.10
DomainCH

IQGAP1 CLMN MACF1 VAV2

2.09e-03731384PS50021
DomainCH-domain

IQGAP1 CLMN MACF1 VAV2

2.31e-03751384IPR001715
DomainKinase-like_dom

PKDCC ARHGAP35 MAP3K4 NRK MACF1 IRAK3 PRKCE STK39 KIT ULK2 STK24

2.32e-0354213811IPR011009
DomainGDS_CDC24_CS

FGD1 DNMBP VAV2

2.97e-03391383IPR001331
DomainPSI

PLXNA1 PLXNB1 PLXNB3

4.19e-03441383IPR016201
Domain-

TTC34 TTC7B TANC1 SEL1L2 CABIN1 CFAP46

4.42e-0320713861.25.40.10
DomainRasGAP

IQGAP1 RASAL2

4.65e-03141382SM00323
DomainLdl_recept_b

LRP1 LRP2

4.65e-03141382PF00058
DomainLDLRB

LRP1 LRP2

4.65e-03141382PS51120
DomainRasGAP_CS

IQGAP1 RASAL2

4.65e-03141382IPR023152
DomainPSI

PLXNA1 PLXNB1 PLXNB3

4.75e-03461383SM00423
DomainRasGAP

IQGAP1 RASAL2

5.34e-03151382PF00616
DomainRAS_GTPASE_ACTIV_1

IQGAP1 RASAL2

5.34e-03151382PS00509
DomainLY

LRP1 LRP2

5.34e-03151382SM00135
DomainRAS_GTPASE_ACTIV_2

IQGAP1 RASAL2

5.34e-03151382PS50018
DomainLDLR_classB_rpt

LRP1 LRP2

5.34e-03151382IPR000033
Domain-

IQGAP1 RASAL2

6.08e-031613821.10.506.10
DomainPROTEIN_KINASE_ATP

PKDCC MAP3K4 NRK IRAK3 PRKCE STK39 KIT ULK2 STK24

7.12e-034591389PS00107
PathwayWP_17Q12_COPY_NUMBER_VARIATION_SYNDROME

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K

8.04e-08991119M46448
PathwayREACTOME_RHO_GTPASE_CYCLE

OCRL NDUFA5 ARHGAP35 IQGAP1 KIDINS220 NISCH FGD1 DNMBP FMNL1 PLXNA1 VAV2 PLXNB1 RASAL2

4.06e-0543911113MM15595
PathwayREACTOME_RHO_GTPASE_CYCLE

OCRL NDUFA5 ARHGAP35 IQGAP1 KIDINS220 NISCH FGD1 DNMBP FMNL1 PLXNA1 VAV2 PLXNB1 RASAL2

5.24e-0545011113M27078
Pubmed

TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

4.15e-27111441116863688
Pubmed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3B TBC1D3G TBC1D3F

2.57e-0874144716625196
Pubmed

PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.

TBC1D3 TBC1D3D TBC1D3F

2.77e-074144312359748
Pubmed

Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.

TBC1D3 TBC1D3D TBC1D3F

2.77e-07414438406013
Pubmed

The Tre2 (USP6) oncogene is a hominoid-specific gene.

TBC1D3 TBC1D3D TBC1D3C

6.91e-075144312604796
Pubmed

Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.

TBC1D3 TBC1D3D TBC1D3F

6.91e-07514438471161
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

AP4E1 KIDINS220 ZNF638 MACF1 TANC1 DNMBP CNOT1 RASAL2 VCPIP1

1.65e-06263144934702444
Pubmed

The expression of plexins during mouse embryogenesis.

PLXNA1 PLXNB1 PLXNB3

3.83e-068144315661641
Pubmed

Proteomic analysis of mammalian primary cilia.

DCDC2 CYRIB WDR35

3.83e-068144322326026
Pubmed

Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.

PLXNA1 PLXNB1 PLXNB3

1.49e-0512144321270798
Pubmed

A human HAP1 homologue. Cloning, expression, and interaction with huntingtin.

HAP1 HTT

1.70e-05214429668110
Pubmed

Huntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase.

IPMK HTT

1.70e-052144226195796
Pubmed

Repurposing of the enhancer-promoter communication underlies the compensation of Mesp2 by Mesp1.

MESP1 MESP2

1.70e-052144235025872
Pubmed

A huntingtin-associated protein enriched in brain with implications for pathology.

HAP1 HTT

1.70e-05214427477378
Pubmed

Elevated zinc transporter ZnT3 in the dentate gyrus of mast cell-deficient mice.

SLC30A3 KIT

1.70e-052144231502721
Pubmed

Plexin-A1 and plexin-B1 specifically interact at their cytoplasmic domains.

PLXNA1 PLXNB1

1.70e-052144212559962
Pubmed

IQGAP1 promotes neurite outgrowth in a phosphorylation-dependent manner.

IQGAP1 PRKCE

1.70e-052144215695813
Pubmed

pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking.

HAP1 HTT

1.70e-052144220515468
Pubmed

Huntingtin-associated protein-1 is a modifier of the age-at-onset of Huntington's disease.

HAP1 HTT

1.70e-052144218192679
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

1.70e-052144234445520
Pubmed

Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models.

GRIN3A HTT

1.70e-052144223852340
Pubmed

Association of HAP1 isoforms with a unique cytoplasmic structure.

HAP1 HTT

1.70e-05214429798945
Pubmed

Transcriptional regulation of Mesp1 and Mesp2 genes: differential usage of enhancers during development.

MESP1 MESP2

1.70e-052144211578861
Pubmed

The roles of Mesp family proteins: functional diversity and redundancy in differentiation of pluripotent stem cells and mammalian mesodermal development.

MESP1 MESP2

1.70e-052144226088191
Pubmed

The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.

HAP1 HTT

1.70e-052144224453320
Pubmed

Plexin signaling hampers integrin-based adhesion, leading to Rho-kinase independent cell rounding, and inhibiting lamellipodia extension and cell motility.

PLXNA1 PLXNB1

1.70e-052144214734633
Pubmed

HAP1-huntingtin interactions do not contribute to the molecular pathology in Huntington's disease transgenic mice.

HAP1 HTT

1.70e-05214429599014
Pubmed

Small-conductance, calcium-activated potassium channels from mammalian brain.

KCNN1 KCNN3

1.70e-05214428781233
Pubmed

Identification of presomitic mesoderm (PSM)-specific Mesp1 enhancer and generation of a PSM-specific Mesp1/Mesp2-null mouse using BAC-based rescue technology.

MESP1 MESP2

1.70e-052144218328678
Pubmed

Huntingtin-associated protein 1 (Hap1) mutant mice bypassing the early postnatal lethality are neuroanatomically normal and fertile but display growth retardation.

HAP1 HTT

1.70e-052144215496430
Pubmed

Human huntingtin-associated protein (HAP-1) gene: genomic organisation and an intragenic polymorphism.

HAP1 HTT

1.70e-052144210974549
Pubmed

OCRL1 function in renal epithelial membrane traffic.

OCRL LRP2

1.70e-052144219940034
Pubmed

Decreased urinary excretion of the ectodomain form of megalin (A-megalin) in children with OCRL gene mutations.

OCRL LRP2

1.70e-052144227766457
Pubmed

Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity.

PTPN5 HTT

1.70e-052144221632937
Pubmed

Kit-negative fibroblast-like cells expressing SK3, a Ca2+-activated K+ channel, in the gut musculature in health and disease.

KCNN3 KIT

1.70e-052144212457234
Pubmed

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

PLXNA1 PLXNB1 PLXNB3

1.93e-0513144310520995
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

PRPF8 TBL3 IQGAP1 KIDINS220 NISCH ZNF638 CNOT1

2.25e-05202144724639526
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

SACS LRP1 LRP2

2.45e-0514144315082773
Pubmed

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.

PLXNA1 PLXNB1 PLXNB3

4.53e-0517144311683995
Pubmed

Semaphorin signaling facilitates cleft formation in the developing salivary gland.

PLXNA1 PLXNB1 PLXNB3

4.53e-0517144317626059
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ACP3 BARD1 ARHGAP35 ATP10A KIDINS220 PTPRB CLMN LRP1 ZNF638 MACF1 PRKCE DHRSX TANC1 PRKAG2 CNOT1 EIF3M VAV2 HTT

4.63e-0514891441828611215
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SETX ERCC6 EP400 SPTLC2 MCM7 OCRL PRPF8 TBL3 IQGAP1 RING1 ZNF638 MACF1 UTP20 TANC1 EIF3M RASAL2 PTCD3

4.75e-0513531441729467282
Pubmed

Molecular properties of small-conductance Ca2+-activated K+ channels expressed in murine colonic smooth muscle.

KCNN1 KCNN3

5.09e-053144211557517
Pubmed

Quantitative expression analysis of the small conductance calcium-activated potassium channels, SK1, SK2 and SK3, in human brain.

KCNN1 KCNN3

5.09e-053144211146124
Pubmed

CircMAP3K4 Suppresses H2O2-Induced Human Lens Epithelial Cell Injury by miR-630/ERCC6 Axis in Age-Related Cataract.

ERCC6 MAP3K4

5.09e-053144238152055
Pubmed

The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia.

NBEA GNAL

5.09e-053144228814779
Pubmed

Interaction of huntingtin-associated protein with dynactin P150Glued.

HAP1 HTT

5.09e-05314429454836
Pubmed

Differential expression of small-conductance Ca2+-activated K+ channels SK1, SK2, and SK3 in mouse atrial and ventricular myocytes.

KCNN1 KCNN3

5.09e-053144216055520
Pubmed

Human endogenous retrovirus W family envelope gene activates the small conductance Ca2+-activated K+ channel in human neuroblastoma cells through CREB.

ERVW-1 KCNN3

5.09e-053144223727510
Pubmed

Diversity of human copy number variation and multicopy genes.

TBC1D3E TBC1D3G

5.09e-053144221030649
Pubmed

Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior.

HAP1 HTT

5.09e-053144211971876
Pubmed

Small conductance Ca2+-activated K+ channel knock-out mice reveal the identity of calcium-dependent afterhyperpolarization currents.

KCNN1 KCNN3

5.09e-053144215190101
Pubmed

Cooperative Mesp activity is required for normal somitogenesis along the anterior-posterior axis.

MESP1 MESP2

5.09e-053144216996494
Pubmed

Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons.

KCNN1 KCNN3

5.09e-053144224434522
Pubmed

Melanotan II causes hypothermia in mice by activation of mast cells and stimulation of histamine 1 receptors.

HRH1 KIT

5.09e-053144229812984
Pubmed

Chemical kindling induced by pentylenetetrazol in histamine H(1) receptor gene knockout mice (H(1)KO), histidine decarboxylase-deficient mice (HDC(-/-)) and mast cell-deficient W/W(v) mice.

HRH1 KIT

5.09e-053144212644274
Pubmed

Comparative immunohistochemical distribution of three small-conductance Ca2+-activated potassium channel subunits, SK1, SK2, and SK3 in mouse brain.

KCNN1 KCNN3

5.09e-053144215234350
Pubmed

Small-conductance calcium-activated K(+) channels 3 (SK3) regulate blastocyst hatching by control of intracellular calcium concentration.

KCNN1 KCNN3

5.09e-053144222416006
Pubmed

MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer.

STK24 VAV2

5.09e-053144226910843
Pubmed

Partial apamin sensitivity of human small conductance Ca2+-activated K+ channels stably expressed in Chinese hamster ovary cells.

KCNN1 KCNN3

5.09e-053144212382077
Pubmed

Cardiac small conductance Ca2+-activated K+ channel subunits form heteromultimers via the coiled-coil domains in the C termini of the channels.

KCNN1 KCNN3

5.09e-053144220689065
Pubmed

Loss of Hap1 selectively promotes striatal degeneration in Huntington disease mice.

HAP1 HTT

5.09e-053144232747555
Pubmed

Regulatory CD4+Foxp3+ T cells control the severity of anaphylaxis.

HRH1 KIT

5.09e-053144223922690
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

EP400 MAP3K4 KIDINS220 NISCH LRRTM2 MACF1 ULK2 PLXNB3 VCPIP1

5.34e-05407144912693553
Pubmed

An investigation into the human serum "interactome".

SETX PTPN5 AP4E1 SACS MACF1 CNOT1

6.11e-05162144615174051
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

MCM7 PRPF8 CNTROB SACS LRRTM2 MACF1 PARP9 CNOT1

7.75e-05332144837433992
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

EP400 BARD1 MUS81 CNTROB RING1 ZNF638 CABIN1 CNOT1 EIF3M VCPIP1 PTCD3

8.28e-056451441125281560
Pubmed

Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease.

HAP1 HTT

1.02e-044144221985783
Pubmed

Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.

LRP1 LRP2

1.02e-044144212413896
Pubmed

Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.

LRP1 LRP2

1.02e-04414427775583
Pubmed

Grb2 mediates semaphorin-4D-dependent RhoA inactivation.

ARHGAP35 PLXNB1

1.02e-044144222505611
Pubmed

A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.

PLXNA1 PLXNB1

1.02e-04414428570614
Pubmed

Polyglutamine expansion of huntingtin impairs its nuclear export.

HAP1 HTT

1.02e-044144215654337
Pubmed

Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) Increases Small-Conductance Ca2+-Activated K+ Current in Patients with Chronic Atrial Fibrillation.

KCNN1 KCNN3

1.02e-044144229737974
Pubmed

Plexin-B family members demonstrate non-redundant expression patterns in the developing mouse nervous system: an anatomical basis for morphogenetic effects of Sema4D during development.

PLXNB1 PLXNB3

1.02e-044144215147296
Pubmed

HAP1 can sequester a subset of TBP in cytoplasmic inclusions via specific interaction with the conserved TBP(CORE).

HAP1 HTT

1.02e-044144217868456
Pubmed

Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.

LRP1 LRP2

1.02e-044144211421580
Pubmed

Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses.

KCNN1 KCNN3

1.02e-044144212882916
Pubmed

Stimulation of NeuroD activity by huntingtin and huntingtin-associated proteins HAP1 and MLK2.

HAP1 HTT

1.02e-044144212881483
Pubmed

SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation.

MCM7 OCRL TTC7B

1.32e-0424144318425126
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

EP400 MCM7 PRPF8 IQGAP1 STK39

1.48e-04120144527320910
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

SETX EP400 DPY19L1 MCM7 CNTROB ZNF638 CNOT1 HYDIN PTCD3

1.56e-04469144927634302
Pubmed

Dynamic coupling between TRPV4 and Ca2+-activated SK1/3 and IK1 K+ channels plays a critical role in regulating the K+-secretory BK channel in kidney collecting duct cells.

KCNN1 KCNN3

1.69e-045144228274924
Pubmed

Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm-specific enhancer of Mesp2.

MESP1 MESP2

1.69e-045144218849530
Pubmed

Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF.

PLXNB1 PLXNB3

1.69e-045144212183458
Pubmed

The activity of the plexin-A1 receptor is regulated by Rac.

PLXNA1 PLXNB1

1.69e-045144215187088
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP1 LRP2

1.69e-045144219047013
Pubmed

Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.

RYR3 PRKCE

1.69e-045144219011160
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

LRP1 LRP2

1.69e-045144218685438
Pubmed

ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.

LRP1 LRP2

1.69e-045144216101684
Pubmed

Plexin-B3 is a functional receptor for semaphorin 5A.

PLXNB1 PLXNB3

1.69e-045144215218527
Pubmed

Interplay between scatter factor receptors and B plexins controls invasive growth.

PLXNB1 PLXNB3

1.69e-045144215184888
Pubmed

Differential contributions of Mesp1 and Mesp2 to the epithelialization and rostro-caudal patterning of somites.

MESP1 MESP2

1.69e-045144215677726
Pubmed

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.

HAP1 HTT

1.69e-045144215242649
Pubmed

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

ERCC6 EP400 ZC3H3 RING1 ZNF638 MACF1 CABIN1

1.79e-04281144724163370
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SPTLC2 ARHGAP35 MON1B ATP10A PPP4R3A SACS WDR35 MACF1 GRIN3A

2.26e-04493144915368895
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

ERCC6 NBEA AK9 PRPF8 RYR3 MAP3K4 PTPRB CNOT1 HYDIN

2.40e-04497144936774506
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

ARHGAP35 KIDINS220 MACF1 TANC1 RASAL2 VCPIP1

2.45e-04209144636779422
Pubmed

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein.

LRP1 LRP2

2.53e-04614429837937
Pubmed

Huntingtin regulates RE1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) nuclear trafficking indirectly through a complex with REST/NRSF-interacting LIM domain protein (RILP) and dynactin p150 Glued.

HAP1 HTT

2.53e-046144218922795
InteractionRAC1 interactions

OCRL NDUFA5 ARHGAP35 MAP3K4 IQGAP1 KIDINS220 FAM171A2 NISCH LRP2 MACF1 UTP20 STK39 TANC1 DNMBP FMNL1 PLXNA1 VAV2 PLXNB1 RASAL2 HTT TBC1D3F

8.01e-06106313521int:RAC1
CytobandEnsembl 112 genes in cytogenetic band chr17q12

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.87e-1214914411chr17q12
Cytoband17q12

TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F

1.60e-0599144517q12
Cytoband15q26.1

MESP1 IQGAP1 MESP2

6.67e-0454144315q26.1
GeneFamilyPlexins

PLXNA1 PLXNB1 PLXNB3

9.48e-069893683
GeneFamilyPotassium calcium-activated channels

KCNN1 KCNN3

3.55e-046892255
GeneFamilyLow density lipoprotein receptors

LRP1 LRP2

1.80e-0313892634
GeneFamilyOlfactory receptors, family 2

OR2T33 OR2C3 OR2AG2 OR2T8

2.35e-03113894149
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC34 TTC7B TANC1 CFAP46

2.50e-03115894769
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA1

TBC1D3 SLC22A15 LPCAT4 FAXC NBEA GRIK3 OCRL PTPN5 LRRTM2 FGD1 KCNN3 GNAL GRIN3A PRKAG2

2.90e-0658413914M39068
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

TBC1D3 SAMD8 SLC22A15 LPCAT4 FAXC NBEA GRIK3 OCRL ARHGAP35 PTPN5 LRRTM2 NINL KCNN3 GNAL GRIN3A HYDIN PLXNA1 VAV2 RASAL2

6.34e-06110613919M39071
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

7.19e-09901389PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlasDE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L GPR27 TBC1D3D TBC1D3C TBC1D3B NINL TBC1D3G TBC1D3K PRODH TBC1D3F

6.27e-0824213812PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D PKDCC TBC1D3C TBC1D3B PTPN5 DNMBP TBC1D3G TBC1D3K TBC1D3F

1.25e-0632013812PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D PCDHA1 TBC1D3C TBC1D3B TBC1D3G PLXNB1 TBC1D3K TBC1D3F

2.33e-0628113811PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D PCDHA1 TBC1D3C TBC1D3B TBC1D3G PLXNB1 TBC1D3K TBC1D3F

2.33e-0628113811PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

1.09e-052131389PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

1.09e-052131389PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
ToppCellfacs-GAT-Fat-3m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCDC2 CDHR3 TTC34 SLC30A3 CCDC148 LRP2 HYDIN LRRC74B

1.39e-071811448e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCellfacs-GAT-Fat-3m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCDC2 CDHR3 TTC34 SLC30A3 CCDC148 LRP2 HYDIN LRRC74B

1.39e-07181144811cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCellfacs-GAT-Fat-3m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCDC2 CDHR3 TTC34 SLC30A3 CCDC148 LRP2 HYDIN LRRC74B

1.39e-0718114485ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDHR3 NBEA AK9 CCDC148 HYDIN CFAP46 LRRC74B

1.33e-06169144714aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HAP1 ACP3 KIF16B CCDC148 CLMN NRK STK39

2.34e-0618414478fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAP1 SLC38A4 LPCAT4 RDH12 RYR3 KCNN3 PRKAG2

2.42e-061851447bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

DPY19L1 ACP3 CPM CCDC148 CLMN NRK STK39

3.55e-06196144704f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RING1 AP4E1 KCNN3 DNMBP ULK2 MFSD3

1.69e-05166144613027ae342994db4540e64eb910df1f42b160931
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RING1 AP4E1 KCNN3 DNMBP ULK2 MFSD3

1.69e-051661446b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DCDC2 CDHR3 HYDIN LRRC36 CFAP46 LRRC74B

2.42e-051771446d947ba38db1772fc5fdcdc211f7511c4aa699dee
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DCDC2 CDHR3 HYDIN LRRC36 CFAP46 LRRC74B

2.42e-051771446d5640f0097878f0dac671e51dc51310278bb2682
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCDC2 CDHR3 SLC30A3 LRP2 HYDIN CFAP46

2.50e-05178144658857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCDC2 CDHR3 SLC30A3 LRP2 HYDIN CFAP46

2.50e-0517814468b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCDC2 CDHR3 SLC30A3 LRP2 HYDIN CFAP46

2.50e-051781446b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RYR3 NINL IRAK3 GNAL GRIN3A KIT

2.66e-051801446b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HAP1 ACP3 KIF16B CCDC148 CLMN STK39

2.75e-05181144622363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDHR3 LRP2 HYDIN LRRC36 CFAP46 LRRC74B

2.83e-051821446587636c0f127231de21acd8aa632b74ff22ca8c2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDHR3 LRP2 HYDIN LRRC36 CFAP46 LRRC74B

2.83e-051821446adfadd7893e74b3002f13f00875e3667d3493e0c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACP3 KIF16B CCDC148 CLMN NRK STK39

3.01e-051841446d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCellP07-Epithelial-airway_epithelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.01e-051841446a5e7af3392e9d6ddad0397f1eeb6b91ed1107cc2
ToppCellP07-Epithelial-airway_epithelial_cell-club_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.01e-051841446ab469b9e06212462cbe2e4db8775c6778db855e6
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDHR3 TTC34 CCDC148 HYDIN LRRC36 LRRC74B

3.01e-051841446264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.01e-051841446797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDHR3 TTC34 CCDC148 HYDIN LRRC36 LRRC74B

3.01e-051841446d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDHR3 TTC34 CCDC148 HYDIN LRRC36 LRRC74B

3.01e-05184144622010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.01e-05184144677d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPM CCDC148 NRK HRH1 HYDIN VAV2

3.20e-051861446f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 CDHR3 LRP2 NINL HRH1 HYDIN

3.20e-051861446b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ACP3 CPM CCDC148 NRK NINL STK39

3.30e-051871446b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPM CCDC148 NRK HRH1 HYDIN VAV2

3.30e-051871446c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HAP1 GRIK3 FIBIN HRH1 GRIN3A

3.33e-051131445feb3c6a7723263d58e5ce020a0097fedfcf78ca8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 CPM CCDC148 HRH1 HYDIN VAV2

3.40e-051881446af740fa78542438fdff627ea1f74f4eee43316be
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

CDHR3 TTC34 CCDC148 HYDIN CFAP46 LRRC74B

3.40e-05188144634b11f72ca73153d02edcd09b38983ad1a504659
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DPY19L1 CPM CLMN NRK STK39 RASAL2

3.40e-05188144643a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.50e-051891446057d7a03fdbe779122b203619a6f947f49b84d28
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN LRRC36 LRRC74B

3.50e-051891446b55de812043b670cbde810d7d42f45909b6d66ef
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.50e-05189144602c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_early|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DCDC2 MCM7 CPM KCNN1 LRP2 LRRC36

3.50e-051891446a6c62b456982067ad4d224a2efa3919969000693
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.50e-051891446164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCellPND10-Epithelial-Epithelial_Airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.50e-051891446407d8a59969d83f014600aae1a55092283a13970
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ACP3 KIF16B RYR3 CCDC148 NRK STK39

3.50e-051891446e059be2965cca70ff5576df055d0af1775b76e00
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.50e-0518914469f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.50e-051891446a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

CDHR3 TTC34 CCDC148 HYDIN CFAP46 LRRC74B

3.50e-051891446b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

CDHR3 TTC34 CCDC148 HYDIN CFAP46 LRRC74B

3.50e-05189144627329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN LRRC36 LRRC74B

3.50e-0518914464e83e49d1265ffe507fdb72924c77c4d1c73f0bd
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.50e-051891446e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 CPM CCDC148 CLMN NRK STK39

3.60e-051901446bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 CPM CCDC148 CLMN NRK STK39

3.60e-051901446b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACP3 SLC22A15 CCDC148 CLMN NRK STK39

3.60e-051901446b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN LRRC36 LRRC74B

3.60e-051901446088e3f39a1e5e11354d6e7458e8e6a39f14936b3
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN LRRC36 LRRC74B

3.60e-05190144635248a8be476ea8d06d67c3d98a25be1f7c150b7
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN LRRC36 LRRC74B

3.60e-0519014465f5206f9e725070d865f4c891ff08bb750e58582
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ACP3 CPM CCDC148 NRK NINL STK39

3.60e-051901446cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.71e-051911446bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.71e-0519114466880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

CDHR3 RYR3 HYDIN PLXNB1 CFAP46 LRRC74B

3.71e-051911446ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACP3 CPM CCDC148 CLMN NRK NINL

3.71e-051911446963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 ACP3 CCDC148 CLMN HRH1 STK39

3.71e-0519114465a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

DCDC2 ACP3 CCDC148 CLMN NRK STK39

3.71e-051911446fe55475ce0666ab5122447a813dc2369e24947b8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 ACP3 CCDC148 CLMN HRH1 STK39

3.71e-05191144655ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellfacs-Lung-EPCAM-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A4 CPM CLMN LRP2 MESP2 PLXNB1

3.71e-051911446629007189034ee8451411428f1c6cc57daee2d91
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

CDHR3 RYR3 HYDIN PLXNB1 CFAP46 LRRC74B

3.71e-0519114466228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 CCDC148 HYDIN LRRC74B

3.71e-05191144696483adb97c81208aa513782550acd8a08b63866
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.82e-051921446b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCellPND03-Epithelial-Epithelial_Airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCDC2 CDHR3 AK9 HYDIN CFAP46 LRRC74B

3.82e-0519214462d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 ACP3 CPM CLMN HRH1 HYDIN

4.05e-051941446e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC2 CPM CCDC148 CLMN NINL PLXNB1

4.05e-0519414465eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDHR3 NBEA AK9 HYDIN CFAP46 LRRC74B

4.05e-0519414464a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDHR3 NBEA AK9 CLMN HYDIN CFAP46

4.16e-0519514469651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDHR3 AK9 KCNN3 HYDIN CFAP46 LRRC74B

4.41e-05197144674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

SETX DDX60 MACF1 PARP9 TANC1 GNAL

4.53e-05198144676d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCellCOVID-19-lung|COVID-19 / Disease (COVID-19 only), tissue and cell type

ATP10A CYRIB LRP1 IRAK3 PARP9 FMNL1

4.66e-051991446155b03b859157013e9142e9248551369127d9204
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-BAGE2|Neuronal / cells hierarchy compared to all cells using T-Statistic

RYR3 NINL IRAK3 GNAL GRIN3A KIT

4.79e-05200144626f07d271e984f375145e4c10528fba44a5811e1
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-BAGE2-L1-2|Neuronal / cells hierarchy compared to all cells using T-Statistic

RYR3 NINL IRAK3 GNAL GRIN3A KIT

4.79e-052001446c3637827ceba16b0d7956c280dd2ddbc8b1ba55e
ToppCellNeuronal-Inhibitory-iA|Neuronal / cells hierarchy compared to all cells using T-Statistic

HAP1 NINL IRAK3 GNAL GRIN3A KIT

4.79e-0520014465ef4a3dc18a44292184a59ced916183c0699b01e
ToppCellControl_saline-Endothelial-Endothelial-Activated_Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

SETX DDX60 KIDINS220 PRKCE PARP9 TANC1

4.79e-052001446be55cef682ba87250dad97689332c8820b3a7420
ToppCellSubstantia_nigra-Macroglia-CSF_related|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CDHR3 AK9 HYDIN LRRC36 LRRC74B

8.05e-05136144547663c5d81c766a333207a44fc5b58b07309ee76
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CDHR3 AK9 HYDIN LRRC36 LRRC74B

8.05e-0513614456d2e5b871f4cf8d64e6fe0be666fb3490797c635
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CDHR3 AK9 HYDIN LRRC36 LRRC74B

8.05e-051361445fd4269d194c7c11c6ab4383393a01efab05cbace
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CDHR3 AK9 HYDIN LRRC36 LRRC74B

8.05e-0513614453f6cec8d52c84191f7f6e2dd4dc47524dfd5b21b
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CDHR3 AK9 HYDIN LRRC36 LRRC74B

8.05e-05136144567d736096d6b6ddb4722809557f5e987063b8d23
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Crh|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC38A4 CDHR3 ATP10A FIBIN KCNN3

8.05e-05136144544f03e4f55fb2c5f8b9397142c89f7194b009cc6
ToppCell(08)_PNEC-(2)_48hpi|(08)_PNEC / shred by cell type and Timepoint

CDHR3 NINL KCNN3 IRAK3 MESP2

9.87e-051421445e95d34170f5053678e0dd9793e68d93c03b05822
ToppCellControl-NK|World / Disease group and Cell class

TTC34 IRAK3 KIT VAV2 RASAL2

1.02e-041431445fe08adc9472dfd4242497d6c614d0490713261da
ToppCellLPS-IL1RA-Endothelial-Mes-Like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PEX10 OCRL RYR3 SACS KCNN1

1.09e-04145144590ca38c02325c5c637c32efdef634b54cc3cd105
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AK9 SACS HYDIN RUSF1 CFAP46

1.28e-04150144553de595376a9fc92491dfd58ff25938b0bf79903
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AK9 SACS HYDIN RUSF1 CFAP46

1.28e-041501445e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-midbrain/hindbrain_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

SLC22A15 RYR3 CLMN GNAL GRIN3A

1.44e-041541445df1b58a20af73fa79c6c069c0117a9ffd85b476f
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

CCDC148 FGD1 PLXNB1 CFAP46 LRRC74B

1.53e-04156144510d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HAP1 GRIK3 FIBIN GRIN3A CFAP46

1.58e-041571445741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX60 ACP3 SLC22A15 RDH12 STK39

1.83e-041621445dddf7a3901ae59e3494d8a6740db0fa15cc96d47
ToppCelldroplet-Lung-LUNG-30m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX60 ACP3 SLC22A15 RDH12 STK39

1.83e-0416214452a4e09545e9874519f0f56e81065104987d81cd6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HAP1 RYR3 IQGAP1 CCDC148 NRK

1.83e-041621445373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellMild-Myeloid-Mast|Mild / Condition, Lineage, Cell class and cell subclass

OR2C3 PTPRB PCDHGA12 TANC1 KIT

1.99e-0416514455fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCellMild-Myeloid-Mast-|Mild / Condition, Lineage, Cell class and cell subclass

OR2C3 PTPRB PCDHGA12 TANC1 KIT

1.99e-04165144593d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCellnucseq-Immune-Hematopoietic-Granulocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NBEA CPM RYR3 TTC7B KIT

1.99e-04165144537615622c736e43260c38016e7c9e565ac97a3e8
ToppCellnucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NBEA CPM RYR3 TTC7B KIT

1.99e-041651445640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCellnucseq-Immune-Hematopoietic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NBEA CPM RYR3 TTC7B KIT

1.99e-041651445f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCelldroplet-Lung-LUNG-1m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT4 CYRIB LRP1 STK24 FMNL1

2.05e-041661445dd5944101ef58a9a29aa3eb5c17690119572b8f1
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

RING1 TANC1 PLXNB1 PLXNB3 RASAL2

2.70e-06491325DOID:0060037 (implicated_via_orthology)
Diseaseproliferative diabetic retinopathy

FAXC CPM KCNN3 PRKAG2

1.64e-04611324EFO_0009322
Diseaseimpulse control disorder

PRKCE PRKAG2

2.94e-0461322MONDO_0001162
Disease3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP) measurement

CYP2C8 DNMBP

2.94e-0461322EFO_0800566
DiseaseColorectal Carcinoma

ERCC6 SLC22A15 GRIK3 GJD4 SACS LRP1 LRP2 HRH1 PRKCE VWA2 RASAL2

3.28e-0470213211C0009402
Diseasenucleotide measurement

GRIK3 PTPRB PRKCE STK39

3.28e-04731324EFO_0010513
Diseaseblood barium measurement

MON1B FIBIN UTP20

4.73e-04341323EFO_0021528
DiseaseSchizophrenia

DCDC2 GRIK3 ERVW-1 SLC30A3 PTPN5 LRP1 LRP2 HRH1 KCNN3 GNAL GRIN3A PRODH

6.27e-0488313212C0036341
DiseaseC-C motif chemokine 18 measurement

PKDCC TBC1D3B

7.00e-0491322EFO_0008046
Diseaseamino acid measurement

SETX RYR3 MAP3K4 PTPRB NISCH LRP2 PRKCE STK39 HTT PRODH

9.73e-0467813210EFO_0005134
Diseaseguanosine diphosphate measurement

NBEA NINL

1.06e-03111322EFO_0010494
DiseaseMalignant neoplasm of breast

ERCC6 KIF16B BARD1 GRIK3 NISCH MACF1 UTP20 KIT EIF3M RUSF1 PLXNB1 RASAL2 PRODH

1.08e-03107413213C0006142
DiseaseCharcot-Marie-Tooth Disease

SETX SPTLC2

1.27e-03121322C0007959
DiseaseLeber congenital amaurosis (implicated_via_orthology)

RDH12 DHRSX

1.50e-03131322DOID:14791 (implicated_via_orthology)
Diseasearm span

CDHR3 IPMK

2.01e-03151322EFO_0005108
DiseaseParkinson disease

OCRL CYRIB FAM171A2 KCNN3 STK39 PARP9

3.30e-033211326MONDO_0005180
DiseaseCCL4 measurement

TBC1D3 TBC1D3F

3.58e-03201322EFO_0004751
Diseasepulse pressure measurement

NBEA PCDHA1 FBXO38 FCSK FAM171A2 LRP1 ZNF638 HRH1 PRKCE NDUFAF6 PRKAG2 CNOT1 HYDIN PTCD3

3.87e-03139213214EFO_0005763
DiseaseIntellectual Disability

NBEA AP4E1 FCSK SACS LRP2 MACF1 HTT

4.07e-034471327C3714756
Diseasecolorectal carcinoma (is_implicated_in)

ERCC6 PTPRB

4.33e-03221322DOID:0080199 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
LKILSYIGSHRELKA

EP400

1166

Q96L91
ISGNALYILTHKRIL

PRKAG2

391

Q9UGJ0
LREAGLHRTLYAKEI

CCDC148

556

Q8NFR7
HVDIVKLLLSYGASR

BARD1

506

Q99728
VVGSKGLSDLYHLRL

CFAP46

1491

Q8IYW2
LRYGLLLLLKHPEVT

CYP2C8

306

P10632
LIKSFIRDLSLYLQH

DNMBP

1036

Q6XZF7
YDLERGKDLSLLHSI

CC2D2B

376

Q6DHV5
RLLTAGTIEEKIYHR

ERCC6

961

Q03468
ALLTFLLHLGIETKT

ATP10A

1211

O60312
LEKRVGYLAVSLFLH

AP4E1

111

Q9UPM8
LKYTAARLHEKGVLL

IQGAP1

1561

P46940
DDLLSTGIILYHLKE

KIF16B

461

Q96L93
LHRDYKGLVLLGILL

PCDHGA12

6

O60330
HTEDYRLRLISLKSG

PTPN5

431

P54829
HLYEIIKGIFLLNRT

PPP4R3A

191

Q6IN85
ILYLGRKEHDILSQL

PARP9

551

Q8IXQ6
LRLIYHVAEKETLLA

MON1B

466

Q7L1V2
SYRLLGVISLLHLVL

PEX10

216

O60683
HFLLTYLLLERLKVS

RDH12

151

Q96NR8
AAAAYLLHELLVIRK

FAXC

76

Q5TGI0
LRDLELAYQVHGLLK

PTCD3

426

Q96EY7
KYIISLADRDLLLIH

PTPRB

496

P23467
LRRVLGKYILLAHST

OR2AG2

301

A6NM03
STRLARHIGYLELLL

KIDINS220

561

Q9ULH0
YLSDHSAIKLELRIK

nan

226

O00370
ELFYGLRKLQTLHLR

LRRTM2

151

O43300
RLLYKDGFSTILHLL

LPCAT4

426

Q643R3
IRYVSELHLTRLKGT

KIT

371

P10721
HGVIYRDLKLDNILL

PRKCE

526

Q02156
LLYSERTILKSIHLS

LRP1

2201

Q07954
KIETLRLAIRYIGHL

MESP2

121

Q0VG99
AILLGLVVLYHAREI

KCNN1

151

Q92952
LTTEKKHTLLRLLYE

EIF3M

156

Q7L2H7
EKLVLVLAHLFGRRY

DDX60

1481

Q8IY21
AGYIIHLLLRTLLEA

GJD4

141

Q96KN9
AVVVGATHLVYLRLL

GPR27

191

Q9NS67
IYKLSGNLTLLRAHV

PLXNA1

71

Q9UIW2
HGKLEYFTDILRTLL

PLXNB1

1646

O43157
SLLSLALHGKLEYLT

PLXNB3

1406

Q9ULL4
STIILLGLIIAYHTR

KCNN3

326

Q9UGI6
GRLLKLSSDLYATTH

LRRC36

391

Q1X8D7
LILSSYGLILAAVLH

OR2T8

211

A6NH00
LDSLLIVISYGLILH

OR51J1

211

Q9H342
LYLTLEILGIKDLHA

NDUFAF6

186

Q330K2
LVTHILRATKLYRGS

DPY19L1

226

Q2PZI1
YIDLGRELSVLHSLL

RASAL2

566

Q9UJF2
LGLLHVRAKDYDTRL

MACF1

521

O94854
EVLTLHGDIRYRKTL

LRP2

1846

P98164
IRIGILIGISKAIHY

IRAK3

266

Q9Y616
LILSSYGLILAAVLH

OR2T33

211

Q8NG76
LVSYGHIARAVLKIR

OR2C3

216

Q8N628
GIHSLLHITLRLKYI

MROH8

276

Q9H579
ATHYSLLATLELLGK

MFSD3

356

Q96ES6
YGLKHLISVLRSILD

IPMK

401

Q8NFU5
GLLSETYLEAHRIVK

MCM7

291

P33993
ILTTIGEHIVYRLLL

GRIN3A

946

Q8TCU5
DLSRYRLLVLVKDHG

PCDHA1

641

Q9Y5I3
TLILYEDLVHILLGS

FAM171A2

131

A8MVW0
RLAYKATHRLLLLGA

GNAL

36

P38405
RELSELSLLSLYGIH

ACP3

236

P15309
LGYLIITAARRLHEV

FBXO38

311

Q6PIJ6
HLLLVYTGKTRLARN

FCSK

926

Q8N0W3
LSKLSELHAYILRVD

HBZ

81

P02008
HSTLLILGVLLTLRY

HTT

306

P42858
LLKAIGSREHIYILN

HYDIN

2251

Q4G0P3
LEVYFRLHASILKLL

CABIN1

1261

Q9Y6J0
ETVGRELLLHLIDYL

CPM

86

P14384
LLVYLVVLLAKAIHR

CDHR3

726

Q6ZTQ4
DYHGAEIVSLRLLSL

C3orf38

191

Q5JPI3
LLGSAKEEILYLRHQ

HAP1

231

P54257
SKLALVLFTYHLQRL

DHRSX

211

Q8N5I4
LTLGLYFLTLLGKHE

MARVELD1

71

Q9BSK0
THLGLDLYLERLRLT

FMNL1

351

O95466
VEGLLNALRYTTKHL

CYRIB

296

Q9NUQ9
RITTVEHLLKSVLLY

GDF9

146

O60383
LLVLYAVRSERKLHT

HRH1

46

P35367
KELAHILGFSYEIRL

GRIK3

471

Q13003
KYELLALTIRSHGTR

FIBIN

186

Q8TAL6
LDLFRYRVLLGHTLI

SLC22A15

296

Q8IZD6
YRLKHLLLEIGFNLV

SACS

3056

Q9NZJ4
KITLRSGAVHRLYTL

DCDC2

176

Q9UHG0
GKTLLLYHLVVIALI

TACR2

191

P21452
TVDHLSKYLALRIAL

RING1

291

Q06587
DLLLYLKRLEHSGTD

CNTROB

826

Q8N137
LLLAHTDLKSLDLSY

LRRC74B

186

Q6ZQY2
YLFILITILKRHTGK

OR5B17

216

Q8NGF7
LLLISYGVILHSLKK

OR4A4P

211

Q8NGN8
LIDAYLLLTKHGDRA

MAP3K4

896

Q9Y6R4
LLITISGHKNRLRVY

NRK

1261

Q7Z2Y5
TLNEGRLRLVLKHYL

RUSF1

286

Q96GQ5
IRRSALLYIALHLKA

AK9

1831

Q5TCS8
RLLETYLILVKHGSG

UTP20

321

O75691
YKGLDLSKLHETLRT

ERVW-1

146

Q9UQF0
TLAQLEKVLHLYRSG

PKDCC

381

Q504Y2
KHRLDGITLLTLTEY

SAMD8

36

Q96LT4
LIYGHLSDRVGRKII

SLC22A24

161

Q8N4F4
ILREILKGLDYLHSE

STK24

136

Q9Y6E0
GLGITKDIHLARRLY

SEL1L2

601

Q5TEA6
FLVIGYLLEKSSRVH

NBEA

551

Q8NFP9
LLQTEKAYVSRLHLL

FGD1

381

P98174
LARHEQLLYVSRKLL

PRODH

86

O43272
TITRAKYSLFILGHL

SETX

2411

Q7Z333
LHDKGLLLRLYTQNI

SIRT3

216

Q9NTG7
KVSSHLVLRSLGSYL

TANC1

691

Q9C0D5
YLKLTLDLFQRGHLV

TANC1

706

Q9C0D5
LNYLLESHLRKLAGE

SPATA31E1

136

Q6ZUB1
TKIETLRLAIRYIGH

MESP1

121

Q9BRJ9
LRLAIRYIGHLSAVL

MESP1

126

Q9BRJ9
AILSLYSVHLLLKTA

SLC38A4

116

Q969I6
DRYGTKQRELLHILL

TBC1D3L

161

B9A6J9
HERLRILYTKILDVL

NDUFA5

21

Q16718
IKHLEQGYRERLSLL

NINL

436

Q9Y2I6
KHIYLSTRIDGSLVI

CYB5R1

81

Q9UHQ9
IGLHKKRIELSVLSY

ARHGAP35

826

Q9NRY4
ILVLHLDRGKDYFLT

OCRL

656

Q01968
LLEVLSGRNLLHEYK

CLMN

71

Q96JQ2
LYKGTLRVLLVLLHD

CNOT1

2091

A5YKK6
SYKHDTKLLILALER

PRPF8

831

Q6P2Q9
DRYGTKQRELLHILL

TBC1D3B

161

A6NDS4
DRYGTKQRELLHILL

TBC1D3H

161

P0C7X1
IRLLQGLIDDYKTLH

ZC3H3

11

Q8IXZ2
DRYGTKQRELLHILL

TBC1D3F

161

A6NER0
VGDLLQLKYSRHRLV

SPTLC2

531

O15270
LLRSGFYDLLISIHL

RYR3

1601

Q15413
RVYGIKDQTFLLHLL

RYR3

2371

Q15413
LHEKRYLRALGLAIS

TBL3

661

Q12788
LLESLSGLHKLYSLV

NISCH

366

Q9Y2I1
SGLHKLYSLVNLDLR

NISCH

371

Q9Y2I1
GRTETELALKYLLHR

VWA2

126

Q5GFL6
ITLLGLLGYLHFVKI

PIGH

71

Q14442
DRYGTKQRELLHILL

TBC1D3E

161

A0A087X179
GSLLYLHDTLEDIKR

VCPIP1

186

Q96JH7
VTGILLYLAFVRLLH

SLC30A3

156

Q99726
RYHKAALLLEGLSRI

ULK2

991

Q8IYT8
ALILHQLGRYSLAEK

TTC7B

771

Q86TV6
DRYGTKQRELLHILL

TBC1D3D

161

A0A087WVF3
LLKSHASGTYLIRER

VAV2

686

P52735
KEIGSLLARYASHLL

WDR35

911

Q9P2L0
TILKEVLEGLDYLHR

STK39

171

Q9UEW8
DRYGTKQRELLHILL

TBC1D3G

161

Q6DHY5
DRYGTKQRELLHILL

TBC1D3

161

Q8IZP1
RAKVILLTGYAHSSL

UPRT

46

Q96BW1
YRLGRLEETHKALLV

TTC34

61

A8MYJ7
DRYGTKQRELLHILL

TBC1D3K

161

A0A087X1G2
LRKEQSLHYGSVLLI

ZNF638

666

Q14966
DRYGTKQRELLHILL

TBC1D3I

161

A0A087WXS9
DRYGTKQRELLHILL

TBC1D3C

161

Q6IPX1
SGARVILLVLYREHL

MUS81

136

Q96NY9