Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIN2A GRIN2B GRIN2C

4.11e-068853GO:0022849
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN2A GRIN2B GRIN2C

4.11e-068853GO:0004972
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIN2A GRIN2B GRIN2C

4.85e-0517853GO:0004970
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters

RIDA EME2 DNASE2

8.05e-0520853GO:0016894
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GABRE GRIN2A GRIN2B GRIN2C

1.02e-0457854GO:1904315
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GABRE GRIN2A GRIN2B GRIN2C

1.24e-0460854GO:0099529
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GABRE GRIN2A GRIN2B GRIN2C

1.70e-0465854GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GABRE GRIN2A GRIN2B GRIN2C

1.70e-0465854GO:0022824
GeneOntologyMolecularFunctionglutamate receptor activity

GRIN2A GRIN2B GRIN2C

2.02e-0427853GO:0008066
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GABRE GRIN2A GRIN2B GRIN2C

2.95e-0475854GO:0098960
GeneOntologyMolecularFunctionligand-gated calcium channel activity

GRIN2A GRIN2B GRIN2C

3.07e-0431853GO:0099604
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GABRE GRIN2A GRIN2B GRIN2C

3.27e-0477854GO:0005230
GeneOntologyMolecularFunctionextracellularly glutamate-gated ion channel activity

GRIN2A GRIN2B

3.71e-047852GO:0005234
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GABRE GRIN2A GRIN2B GRIN2C

8.79e-04100854GO:0030594
GeneOntologyMolecularFunctionDNA endonuclease activity, producing 3'-phosphomonoesters

EME2 DNASE2

9.61e-0411852GO:0016889
GeneOntologyMolecularFunctioncell adhesion molecule binding

PTPRB DSG2 P4HB ADAM18 TENM1 GRIN2A GRIN2B CTNND2 NOS2

1.00e-03599859GO:0050839
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GABRE CLCA2 GRIN2A GRIN2B GRIN2C

1.41e-03193855GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

GABRE CLCA2 GRIN2A GRIN2B GRIN2C

1.54e-03197855GO:0022834
GeneOntologyMolecularFunctionglutamate binding

GRIN2A GRIN2B

1.58e-0314852GO:0016595
GeneOntologyMolecularFunctionpeptidase activity

MEP1A KY RELN PSEN2 CLCA2 ADAM18 USP32 HMCES USP21

1.84e-03654859GO:0008233
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

LPIN1 RIDA RNASEL PTPRB PTPRG PFKFB3 EME2 IDS PLA2G15 DNASE2

2.22e-038078510GO:0016788
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRB PTPRG

2.34e-0317852GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRB PTPRG

2.34e-0317852GO:0019198
GeneOntologyMolecularFunctionNADP binding

DECR1 NOX1 NOS2

2.35e-0362853GO:0050661
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DYNC2H1 DNAH7

2.62e-0318852GO:0008569
GeneOntologyMolecularFunctionendonuclease activity

RIDA RNASEL EME2 DNASE2

2.72e-03136854GO:0004519
GeneOntologyMolecularFunctionamino acid binding

GRIN2A GRIN2B NOS2

3.74e-0373853GO:0016597
GeneOntologyBiologicalProcesspositive regulation of excitatory postsynaptic potential

RELN GRIN2A GRIN2B GRIN2C

3.07e-0543864GO:2000463
GeneOntologyBiologicalProcesspositive regulation of synaptic transmission, glutamatergic

RELN GRIN2A GRIN2B GRIN2C

3.07e-0543864GO:0051968
GeneOntologyBiologicalProcessexcitatory chemical synaptic transmission

GRIN2A GRIN2B GRIN2C

3.77e-0516863GO:0098976
GeneOntologyBiologicalProcessdirectional locomotion

GRIN2A GRIN2C

1.03e-044862GO:0033058
GeneOntologyBiologicalProcessregulation of membrane potential

GABRE RELN BCO2 DSG2 FOXP1 GRIN2A GRIN2B GRIN2C SLC4A4 PPP2R3C

1.10e-045598610GO:0042391
GeneOntologyBiologicalProcessorganic acid catabolic process

DECR1 LPIN1 RIDA ACAD11 IDS NOS2 PLA2G15

1.42e-04272867GO:0016054
GeneOntologyBiologicalProcesscarboxylic acid catabolic process

DECR1 LPIN1 RIDA ACAD11 IDS NOS2 PLA2G15

1.42e-04272867GO:0046395
GeneOntologyBiologicalProcessmodulation of excitatory postsynaptic potential

RELN GRIN2A GRIN2B GRIN2C

1.57e-0465864GO:0098815
GeneOntologyBiologicalProcessionotropic glutamate receptor signaling pathway

GRIN2A GRIN2B GRIN2C

1.90e-0427863GO:0035235
GeneOntologyCellularComponentNMDA selective glutamate receptor complex

GRIN2A GRIN2B GRIN2C

5.35e-069853GO:0017146
GeneOntologyCellularComponentionotropic glutamate receptor complex

OLFM1 GRIN2A GRIN2B GRIN2C

3.34e-0545854GO:0008328
GeneOntologyCellularComponentneurotransmitter receptor complex

OLFM1 GRIN2A GRIN2B GRIN2C

5.08e-0550854GO:0098878
GeneOntologyCellularComponentpostsynaptic density membrane

OLFM1 ROBO2 GRIN2A GRIN2B GRIN2C

4.53e-04157855GO:0098839
MousePhenoabnormal NMDA-mediated synaptic currents

MAPK8IP1 GRIN2A GRIN2B GRIN2C

4.41e-0622724MP:0002888
DomainNMDAR2_C

GRIN2A GRIN2B GRIN2C

8.78e-083843PF10565
DomainNMDAR2_C

GRIN2A GRIN2B GRIN2C

8.78e-083843IPR018884
DomainIontro_rcpt

GRIN2A GRIN2B GRIN2C

6.82e-0518843IPR001320
DomainLig_chan-Glu_bd

GRIN2A GRIN2B GRIN2C

6.82e-0518843PF10613
DomainIono_rcpt_met

GRIN2A GRIN2B GRIN2C

6.82e-0518843IPR001508
DomainGlu/Gly-bd

GRIN2A GRIN2B GRIN2C

6.82e-0518843IPR019594
DomainLig_chan-Glu_bd

GRIN2A GRIN2B GRIN2C

6.82e-0518843SM00918
DomainLig_chan

GRIN2A GRIN2B GRIN2C

6.82e-0518843PF00060
DomainPBPe

GRIN2A GRIN2B GRIN2C

6.82e-0518843SM00079
DomainDesmosomal_cadherin

DSC3 DSG2

4.14e-047842IPR009122
DomainANF_lig-bd_rcpt

GRIN2A GRIN2B GRIN2C

6.11e-0437843IPR001828
DomainANF_receptor

GRIN2A GRIN2B GRIN2C

6.11e-0437843PF01094
DomainPeripla_BP_I

GRIN2A GRIN2B GRIN2C

7.14e-0439843IPR028082
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DNAH7

1.76e-0314842IPR024317
DomainDynein_HC_stalk

DYNC2H1 DNAH7

1.76e-0314842IPR024743
DomainDynein_heavy_dom-2

DYNC2H1 DNAH7

1.76e-0314842IPR013602
DomainDHC_N2

DYNC2H1 DNAH7

1.76e-0314842PF08393
DomainMT

DYNC2H1 DNAH7

1.76e-0314842PF12777
DomainAAA_8

DYNC2H1 DNAH7

1.76e-0314842PF12780
DomainDHC_fam

DYNC2H1 DNAH7

2.02e-0315842IPR026983
DomainDynein_heavy_dom

DYNC2H1 DNAH7

2.02e-0315842IPR004273
DomainDynein_heavy

DYNC2H1 DNAH7

2.02e-0315842PF03028
DomainEGF_extracell

RELN ADAM18 TENM1

2.50e-0360843IPR013111
DomainEGF_2

RELN ADAM18 TENM1

2.50e-0360843PF07974
DomainFd_Rdtase_FAD-bd

NOX1 NOS2

3.25e-0319842IPR017927
DomainFAD_FR

NOX1 NOS2

3.25e-0319842PS51384
DomainRiboflavin_synthase-like_b-brl

NOX1 NOS2

3.25e-0319842IPR017938
DomainHEAT_REPEAT

PDS5B SMG1 PDS5A

3.87e-0370843PS50077
DomainEGF-like_dom

MEP1A RELN ADAM18 TENM1 TECTA

5.31e-03249845IPR000742
DomainCadherin_cytoplasmic-dom

DSC3 DSG2

5.61e-0325842IPR000233
DomainCadherin_C

DSC3 DSG2

5.61e-0325842PF01049
PathwayKEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B GRIN2C

1.02e-065673M47667
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B GRIN2C

2.03e-066673M47668
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B GRIN2C

4.48e-0515673M47691
PathwayWP_NOCGMPPKG_MEDIATED_NEUROPROTECTION

GRIN2A GRIN2B GRIN2C NOS2

7.13e-0547674M39531
PathwayWP_NRXN1_DELETION_SYNDROME

GRIN2A GRIN2B GRIN2C

7.96e-0518673M48098
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B GRIN2C

7.96e-0518673M47761
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B GRIN2C

9.42e-0519673M47677
PathwayBIOCARTA_NOS1_PATHWAY

GRIN2A GRIN2B GRIN2C

1.10e-0420673MM1445
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

GRIN2A GRIN2B GRIN2C

1.28e-0421673M27736
PathwayBIOCARTA_NOS1_PATHWAY

GRIN2A GRIN2B GRIN2C

1.28e-0421673M11650
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

GRIN2A GRIN2B GRIN2C

1.28e-0421673M838
PathwayREACTOME_NEGATIVE_REGULATION_OF_NMDA_RECEPTOR_MEDIATED_NEURONAL_TRANSMISSION

GRIN2A GRIN2B GRIN2C

1.28e-0421673M27944
PathwayREACTOME_LONG_TERM_POTENTIATION

GRIN2A GRIN2B GRIN2C

1.70e-0423673M27949
PathwayREACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS

GRIN2A GRIN2C

2.20e-045672MM15655
PathwayPID_REELIN_PATHWAY

RELN GRIN2A GRIN2B

3.09e-0428673M69
PathwayWP_ALZHEIMERS_DISEASE

PSEN2 GRIN2A GRIN2B GRIN2C

4.18e-0474674MM15962
PathwayKEGG_MEDICUS_REFERENCE_ESTABLISHMENT_OF_COHESION

PDS5B PDS5A

4.60e-047672M47869
PathwayWP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV

GRIN2A GRIN2B GRIN2C

5.06e-0433673M39875
PathwayWP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION

GRIN2A GRIN2B GRIN2C

6.55e-0436673M39831
PathwayREACTOME_COHESIN_LOADING_ONTO_CHROMATIN

PDS5B PDS5A

9.77e-0410672M27178
PathwayREACTOME_COHESIN_LOADING_ONTO_CHROMATIN

PDS5B PDS5A

9.77e-0410672MM14892
PathwayREACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS

GRIN2A GRIN2B GRIN2C

1.18e-0344673M27934
PathwayREACTOME_ESTABLISHMENT_OF_SISTER_CHROMATID_COHESION

PDS5B PDS5A

1.19e-0311672M27177
PathwayREACTOME_ESTABLISHMENT_OF_SISTER_CHROMATID_COHESION

PDS5B PDS5A

1.19e-0311672MM14891
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_LIGAND_GATED_CA2_CHANNEL

GRIN2A GRIN2C

1.42e-0312672M47953
PathwayWP_ALZHEIMERS_DISEASE

NOX1 PSEN2 GRIN2A GRIN2B GRIN2C NOS2

1.48e-03261676M42565
PathwayWP_RETT_SYNDROME

HIVEP2 GRIN2A GRIN2B

1.52e-0348673M39759
PathwayREACTOME_MITOTIC_TELOPHASE_CYTOKINESIS

PDS5B PDS5A

1.68e-0313672MM15363
PathwayREACTOME_MITOTIC_TELOPHASE_CYTOKINESIS

PDS5B PDS5A

1.68e-0313672M27661
PathwayWP_SYNAPTIC_SIGNALING_ASSOCIATED_WITH_AUTISM_SPECTRUM_DISORDER

GRIN2A GRIN2B GRIN2C

1.71e-0350673M39822
Pubmed

Modified N-methyl-D-aspartate receptor subunit expression emerges in reeler Purkinje cells after accomplishment of the adult wild-type expression.

RELN GRIN2A GRIN2B GRIN2C

1.74e-1058649004271
Pubmed

Long-term NR2B expression in the cerebellum alters granule cell development and leads to NR2A down-regulation and motor deficits.

GRIN2A GRIN2B GRIN2C

1.46e-08386315519237
Pubmed

Dual regulation of NR2B and NR2C expression by NMDA receptor activation in mouse cerebellar granule cell cultures.

GRIN2A GRIN2B GRIN2C

1.46e-08386318685090
Pubmed

Molecular diversity of the NMDA receptor channel.

GRIN2A GRIN2B GRIN2C

5.83e-0848631377365
Pubmed

Heteromeric NMDA receptors: molecular and functional distinction of subtypes.

GRIN2A GRIN2B GRIN2C

5.83e-0848631350383
Pubmed

Differential expression and co-assembly of NMDA zeta 1 and epsilon subunits in the mouse cerebellum during postnatal development.

GRIN2A GRIN2B GRIN2C

5.83e-0848638595214
Pubmed

Functional correlation of NMDA receptor epsilon subunits expression with the properties of single-channel and synaptic currents in the developing cerebellum.

GRIN2A GRIN2B GRIN2C

5.83e-0848638699248
Pubmed

Chronic ethanol treatment produces a selective upregulation of the NMDA receptor subunit gene expression in mammalian cultured cortical neurons.

GRIN2A GRIN2B GRIN2C

5.83e-0848638965641
Pubmed

NMDA receptor upregulation: molecular studies in cultured mouse cortical neurons after chronic antagonist exposure.

GRIN2A GRIN2B GRIN2C

5.83e-0848638601798
Pubmed

Role of the carboxy-terminal region of the GluR epsilon2 subunit in synaptic localization of the NMDA receptor channel.

GRIN2A GRIN2B GRIN2C

5.83e-0848639768843
Pubmed

Synapse-selective impairment of NMDA receptor functions in mice lacking NMDA receptor epsilon 1 or epsilon 2 subunit.

GRIN2A GRIN2B GRIN2C

1.45e-0758639147327
Pubmed

Heterozygous deletion of NR1 subunit of the NMDA receptor alters ethanol-related behaviors and regional expression of NR2 subunits in the brain.

GRIN2A GRIN2B GRIN2C

1.45e-07586321945132
Pubmed

Roles of the glutamate receptor epsilon2 and delta2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex.

GRIN2A GRIN2B GRIN2C

1.45e-07586311488959
Pubmed

Differential distributions of the NMDA receptor channel subunit mRNAs in the mouse retina.

GRIN2A GRIN2B GRIN2C

1.45e-0758637510577
Pubmed

Distinct spatiotemporal distributions of the N-methyl-D-aspartate receptor channel subunit mRNAs in the mouse cervical cord.

GRIN2A GRIN2B GRIN2C

1.45e-0758637929904
Pubmed

Reelin signaling facilitates maturation of CA1 glutamatergic synapses.

RELN GRIN2A GRIN2B

1.45e-07586317229826
Pubmed

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.

GRIN2A GRIN2B GRIN2C

1.45e-07586326919761
Pubmed

Distinct distributions of five NMDA receptor channel subunit mRNAs in the brainstem.

GRIN2A GRIN2B GRIN2C

1.45e-0758637518475
Pubmed

Distinct spatiotemporal expressions of five NMDA receptor channel subunit mRNAs in the cerebellum.

GRIN2A GRIN2B GRIN2C

1.45e-0758637518474
Pubmed

Distinct gene expression of the N-methyl-D-aspartate receptor channel subunit in peripheral neurons of the mouse sensory ganglia and adrenal gland.

GRIN2A GRIN2B GRIN2C

1.45e-0758638015722
Pubmed

Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain.

GRIN2A GRIN2B GRIN2C

1.45e-07586315003177
Pubmed

GABAA, GABAC, and NMDA receptor subunit expression in the suprachiasmatic nucleus and other brain regions.

GRIN2A GRIN2B GRIN2C

1.45e-0758637723623
Pubmed

Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor.

GRIN2A GRIN2B GRIN2C

1.45e-07586312082569
Pubmed

Developmental changes in distribution of NMDA receptor channel subunit mRNAs.

GRIN2A GRIN2B GRIN2C

1.45e-0758631493227
Pubmed

N-methyl-D-aspartic acid receptor structure and function.

GRIN2A GRIN2B GRIN2C

1.45e-0758638036251
Pubmed

NMDA receptor activation by HIV-Tat protein is clade dependent.

GRIN2A GRIN2B GRIN2C

1.45e-07586319020013
Pubmed

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.

GRIN2A GRIN2B GRIN2C

1.45e-07586326875626
Pubmed

Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene.

GRIN2A GRIN2B GRIN2C

1.45e-0758638756432
Pubmed

Differential interaction of NMDA receptor subtypes with the post-synaptic density-95 family of membrane associated guanylate kinase proteins.

GRIN2A GRIN2B GRIN2C

1.45e-07586318233995
Pubmed

A role for spermine oxidase as a mediator of reactive oxygen species production in HIV-Tat-induced neuronal toxicity.

GRIN2A GRIN2B GRIN2C

2.90e-07686323665428
Pubmed

Altered gene expression of the N-methyl-D-aspartate receptor channel subunits in Purkinje cells of the staggerer mutant mouse.

GRIN2A GRIN2B GRIN2C

2.90e-0768638996814
Pubmed

Cortical consequences of HIV-1 Tat exposure in rats are enhanced by chronic cocaine.

GRIN2A GRIN2B GRIN2C

2.90e-07686325760043
Pubmed

Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo.

GRIN2A GRIN2B GRIN2C

2.90e-0768639458051
Pubmed

NMDA receptor GluRepsilon/NR2 subunits are essential for postsynaptic localization and protein stability of GluRzeta1/NR1 subunit.

GRIN2A GRIN2B GRIN2C

2.90e-07686315317856
Pubmed

Early onset of NMDA receptor GluR epsilon 1 (NR2A) expression and its abundant postsynaptic localization in developing motoneurons of the mouse hypoglossal nucleus.

GRIN2A GRIN2B GRIN2C

5.07e-07786312103442
Pubmed

Human immunodeficiency virus-1 protein Tat induces excitotoxic loss of presynaptic terminals in hippocampal cultures.

GRIN2A GRIN2B GRIN2C

5.07e-07786323267846
Pubmed

Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death.

GRIN2A GRIN2B GRIN2C

5.07e-07786319036954
Pubmed

Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain.

RELN GRIN2A GRIN2B

5.07e-07786321664258
Pubmed

NMDA-receptor proteins are upregulated in the hippocampus of postnatal heterozygous reeler mice.

RELN GRIN2A GRIN2B

5.07e-07786316438943
Pubmed

HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors.

GRIN2A GRIN2B GRIN2C

5.07e-07786322940423
Pubmed

Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia.

GRIN2A GRIN2B GRIN2C

5.07e-07786322833210
Pubmed

HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce neurotoxicity in human embryonic neurons.

GRIN2A GRIN2B GRIN2C

8.10e-0788638563977
Pubmed

Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity.

GRIN2A GRIN2B GRIN2C

8.10e-0788637695237
Pubmed

HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes.

GRIN2A GRIN2B GRIN2C

8.10e-07886317360663
Pubmed

Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120.

GRIN2A GRIN2B GRIN2C

8.10e-0788638724036
Pubmed

Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine.

GRIN2A GRIN2B GRIN2C

8.10e-0788638822372
Pubmed

Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-ß production.

GRIN2A GRIN2B GRIN2C

8.10e-07886321106831
Pubmed

Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures.

GRIN2A GRIN2B GRIN2C

8.10e-07886310448428
Pubmed

Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase.

GRIN2A GRIN2B GRIN2C

8.10e-0788638955056
Pubmed

Evidence of HIV type 1 glycoprotein 120 binding to recombinant N-methyl-D-aspartate receptor subunits expressed in a baculovirus system.

GRIN2A GRIN2B GRIN2C

8.10e-07886310555109
Pubmed

Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons.

GRIN2A GRIN2B GRIN2C

8.10e-0788638804048
Pubmed

The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid.

GRIN2A GRIN2B GRIN2C

8.10e-0788638845955
Pubmed

HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures.

GRIN2A GRIN2B GRIN2C

8.10e-0788638821747
Pubmed

Activation of cannabinoid type 2 receptors inhibits HIV-1 envelope glycoprotein gp120-induced synapse loss.

GRIN2A GRIN2B GRIN2C

1.21e-06986321670103
Pubmed

Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems.

GRIN2A GRIN2B GRIN2C

1.21e-06986317526495
Pubmed

Human immunodeficiency virus type 1 clade B and C gp120 differentially induce neurotoxin arachidonic acid in human astrocytes: implications for neuroAIDS.

GRIN2A GRIN2B GRIN2C

1.21e-06986321491143
Pubmed

D1/NMDA receptors and concurrent methamphetamine+ HIV-1 Tat neurotoxicity.

GRIN2A GRIN2B GRIN2C

1.21e-06986322552781
Pubmed

PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A.

GRIN2A GRIN2B GRIN2C

1.21e-0698639892651
Pubmed

Maternal stress produces learning deficits associated with impairment of NMDA receptor-mediated synaptic plasticity.

GRIN2A GRIN2B GRIN2C

1.21e-06986316554481
Pubmed

N-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neurons.

GRIN2A GRIN2B GRIN2C

1.73e-061086319332541
Pubmed

HIV-1 Tat-mediated apoptosis in human blood-retinal barrier-associated cells.

GRIN2A GRIN2B GRIN2C

2.37e-061186324739951
Pubmed

Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase.

GRIN2A GRIN2B GRIN2C

2.37e-06118638581564
Pubmed

CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins.

GRIN2A GRIN2B GRIN2C

2.37e-06118639647694
Pubmed

Effects of SDF-1alpha and gp120IIIB on apoptotic pathways in SK-N-SH neuroblastoma cells.

GRIN2A GRIN2B GRIN2C

2.37e-061186316481105
Pubmed

Developmental rearrangements of cortical glutamate-NMDA receptor binding sites in late human gestation.

GRIN2A GRIN2B GRIN2C

3.16e-06128638665664
Pubmed

Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle.

GRIN2A GRIN2B GRIN2C

3.16e-061286312815021
Pubmed

Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102.

GRIN2A GRIN2B GRIN2C

3.16e-061286311937501
Pubmed

Crybb2 coding for βB2-crystallin affects sensorimotor gating and hippocampal function.

GRIN2A GRIN2B GRIN2C

4.10e-061386324096375
Pubmed

Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways.

GRIN2A GRIN2B GRIN2C

5.21e-061486315749123
Pubmed

Attenuation of focal cerebral infarct in mice lacking NMDA receptor subunit NR2C.

GRIN2A GRIN2C

6.04e-0628629512392
Pubmed

The glutamate receptor GluN2 subunit regulates synaptic trafficking of AMPA receptors in the neonatal mouse brain.

GRIN2A GRIN2B

6.04e-06286225131300
Pubmed

NMDA receptor NR2B subunit over-expression increases cerebellar granule cell migratory activity.

GRIN2B GRIN2C

6.04e-06286218005003
Pubmed

Conditioned eyeblink response is impaired in mutant mice lacking NMDA receptor subunit NR2A.

GRIN2A GRIN2C

6.04e-0628629427357
Pubmed

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms.

GRIN2A GRIN2B

6.04e-06286220921396
Pubmed

The GRIN2B and GRIN2A Gene Variants Are Associated With Continuous Performance Test Variables in ADHD.

GRIN2A GRIN2B

6.04e-06286227199241
Pubmed

The role of NMDAR subtypes and charge transfer during hippocampal LTP induction.

GRIN2A GRIN2B

6.04e-06286216901514
Pubmed

N-methyl-D-aspartate receptor subtype 2C is not involved in circadian oscillation or photoic entrainment of the biological clock in mice.

GRIN2A GRIN2C

6.04e-06286210972963
Pubmed

Specific involvement of postsynaptic GluN2B-containing NMDA receptors in the developmental elimination of corticospinal synapses.

GRIN2A GRIN2B

6.04e-06286220696923
Pubmed

NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.

GRIN2A GRIN2B

6.04e-06286223618906
Pubmed

Both NR2A and NR2B subunits of the NMDA receptor are critical for long-term potentiation and long-term depression in the lateral amygdala of horizontal slices of adult mice.

GRIN2A GRIN2B

6.04e-06286219474217
Pubmed

PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.

PDS5B PDS5A

6.04e-06286231757807
Pubmed

Importance of the GluN2B carboxy-terminal domain for enhancement of social memories.

GRIN2A GRIN2B

6.04e-06286226179233
Pubmed

Hypoxia induces nitric oxide synthase in rheumatoid synoviocytes: consequences on NADPH oxidase regulation.

NOX1 NOS2

6.04e-06286222329647
Pubmed

Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation.

GRIN2A GRIN2B

6.04e-06286216033900
Pubmed

iNOS- and NOX1-dependent ROS production maintains bacterial homeostasis in the ileum of mice.

NOX1 NOS2

6.04e-06286229210363
Pubmed

Association of GRIN1 and GRIN2A-D with schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk.

GRIN2B GRIN2C

6.04e-06286221919190
Pubmed

Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids.

GRIN2A GRIN2B

6.04e-06286238214768
Pubmed

[Different distribution of NMDA receptor subunits in cortex contributes to selective vulnerability of motor neurons in amyotrophic lateral sclerosis].

GRIN2A GRIN2B

6.04e-06286221503117
Pubmed

Functional contributions of synaptically localized NR2B subunits of the NMDA receptor to synaptic transmission and long-term potentiation in the adult mouse CNS.

GRIN2A GRIN2B

6.04e-06286218372311
Pubmed

Effects of GluN2A and GluN2B gain-of-function epilepsy mutations on synaptic currents mediated by diheteromeric and triheteromeric NMDA receptors.

GRIN2A GRIN2B

6.04e-06286232247039
Pubmed

PDS5A and PDS5B in Cohesin Function and Human Disease.

PDS5B PDS5A

6.04e-06286234070827
Pubmed

NMDA receptor 2 (NR2) C-terminal control of NR open probability regulates synaptic transmission and plasticity at a cerebellar synapse.

GRIN2A GRIN2C

6.04e-06286212427824
Pubmed

Separate functional properties of NMDARs regulate distinct aspects of spatial cognition.

GRIN2A GRIN2B

6.04e-06286229764972
Pubmed

Increasing the GluN2A/GluN2B Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace.

GRIN2A GRIN2B

6.04e-06286227605622
Pubmed

Disease-associated GRIN protein truncating variants trigger NMDA receptor loss-of-function.

GRIN2A GRIN2B

6.04e-06286233043365
Pubmed

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences.

GRIN2A GRIN2B

6.04e-06286230355491
Pubmed

N-methyl-D-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease.

GRIN2A GRIN2B

6.04e-06286212127670
Pubmed

Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.

GRIN2A GRIN2B

6.04e-06286220890276
Pubmed

Roles of NMDA receptor NR2A and NR2B subtypes for long-term depression in the anterior cingulate cortex.

GRIN2A GRIN2B

6.04e-06286216045501
Pubmed

NR2A- and NR2B-NMDA receptors and drebrin within postsynaptic spines of the hippocampus correlate with hunger-evoked exercise.

GRIN2A GRIN2B

6.04e-06286227915379
Cytoband5q11.2

SETD9 GAPT MTREX

1.31e-04528635q11.2
CytobandEnsembl 112 genes in cytogenetic band chr5q11

SETD9 GAPT MTREX

7.76e-0495863chr5q11
CytobandEnsembl 112 genes in cytogenetic band chr18q12

DSC3 DSG2 ZNF396

1.01e-03104863chr18q12
Cytoband18q12.1

DSC3 DSG2

1.09e-032686218q12.1
Cytoband17q25

P4HB GRIN2C

2.46e-033986217q25
Cytoband4p14

TLR1 PDS5A

2.84e-03428624p14
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2A GRIN2B GRIN2C

8.26e-0775331201
GeneFamilyDesmosomal cadherins

DSC3 DSG2

1.75e-0475321188
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRB PTPRG

1.71e-0321532813
CoexpressionSENESE_HDAC3_TARGETS_UP

MAPK8IP1 LPIN1 SMG1 HIVEP2 PTPRB COPA TCN1 USP32 OLFM1 IDS PRDM1

6.67e-074958611M8451
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SPATA17 CFAP300 BCO2 DYNC2H1 SPAG17 DNAH7

1.75e-0618886682c006f43c93f4a867953a446864f02b44536a23
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SPATA17 CFAP300 BCO2 DYNC2H1 SPAG17 DNAH7

1.75e-06188866da59b5c0a4b11690a39a964c1a0a83e66aa0972b
ToppCellfacs-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN PTPRB SGMS1 PTPRG HOXD8 MTREX

2.16e-061958667f9b7f15006610ad591063d90e90367bd6083c7f
ToppCellCaecum-(2)_B_cell-(21)_B_cell_IgG_Plasma|Caecum / shred on region, Cell_type, and subtype

PTPRG P4HB BLNK MYDGF HMCES DDOST

2.36e-061988663893fcfc1de5937be3ccc7e545f711f2c95a2827
ToppCellPSB|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NDNF CFAP300 CLCA2 DYNC2H1 SLC4A4 SPAG17

2.36e-061988664e6b0d1abc55d7a0d89bd7ecf0f13dc5bed66626
ToppCellCaecum-B_cell-B_cell_IgG_Plasma|Caecum / Region, Cell class and subclass

PTPRG P4HB BLNK MYDGF HMCES DDOST

2.36e-06198866d8cb78b1763710a158cf22b59aebaa44afd2374c
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

DSC3 DSG2 TECTA SLC4A4 PRG4

1.76e-051668654d63c758d46e73311b864148c646bf081498dee7
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|356C / Donor, Lineage, Cell class and subclass (all cells)

GABRE RELN PTPRB HOXD8 GRIN2B

1.76e-051668655ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|356C / Donor, Lineage, Cell class and subclass (all cells)

GABRE RELN PTPRB HOXD8 GRIN2B

1.76e-051668656bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCell368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

DSC3 DSG2 TECTA SLC4A4 PRG4

1.76e-051668654160ccf9291072a6e2782f9ad141bc9a9747f3ad
ToppCellfacs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN CLCA2 DYNC2H1 DNMBP DNASE2

1.81e-05167865961e722442d786ab15d1e490941d2be265a9057a
ToppCellfacs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN CLCA2 DYNC2H1 DNMBP DNASE2

1.81e-051678653760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCellnormal_Lung-Fibroblasts-Mesothelial_cells|normal_Lung / Location, Cell class and cell subclass

DSC3 TCN1 CLCA2 DSG2 PRG4

2.33e-05176865f31d7234053085a82cf9d55aeedd1e04d34789c3
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA17 CFAP300 TCN1 DSG2 SPAG17

2.40e-05177865e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_CPZ|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRB DSG2 TENM1 TECTA HS3ST2

2.40e-0517786557033ee0d49a4a50fc25328a4a44d4de2b35f505
ToppCellCOVID-19-Heart-Lymph_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

GABRE RELN HOXD8 OLFM1 GRIN2B

2.40e-05177865326fde0734ef0d7272693966d346ca479b9d8147
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA17 CFAP300 TCN1 DSG2 SPAG17

2.46e-05178865b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA17 CFAP300 TCN1 DSG2 SPAG17

2.46e-05178865579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 LPIN1 PFKFB3 SPAG17 DNAH7

2.67e-051818656a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TENM1 GRIN2B SLC4A4 SPAG17

2.89e-051848652cbed6462fea2622871bb7e49b0df3d984239281
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN TENM1 ROBO2 PRDM1

2.89e-051848657f6c8912677764d438ab0555faca344d74c2f483
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 SETX PHF3 PDS5A FOXP1

2.89e-051848651154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TENM1 GRIN2B SLC4A4 SPAG17

2.89e-05184865ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellILEUM-inflamed-(1)_T_cell-(1)_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LPIN1 SMG1 PFKFB3 IDS PRDM1

2.89e-05184865cef3ee2a4a0af961aa3b4c92150d423e841ae8c1
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TENM1 GRIN2B SLC4A4 SPAG17

2.89e-051848652b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.04e-0518686576033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN TENM1 ROBO2 PRDM1

3.12e-0518786585f1678338a47d91e296f0620d4887f057eb7e70
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.12e-05187865e61992de4f98eeea08b43213850769d923f8db48
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

GABRE RELN PTPRB HOXD8 GRIN2B

3.12e-051878651e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.20e-05188865803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNT14 HOXD8 DYNC2H1 BLNK DEPDC1B

3.20e-051888651d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.20e-051888655ba5cbb403518026e9040379fb5d99339ea977d8
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Hpcal1-Fos_(Entorhinal_cortex_(IEG))|Hippocampus / BrainAtlas - Mouse McCarroll V32

KY NOX1 ADAM18 BLNK

3.33e-0594864a4d0eefede392b55d17ae9995237a2278a570e42
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Hpcal1-Fos_(Entorhinal_cortex_(IEG))-|Hippocampus / BrainAtlas - Mouse McCarroll V32

KY NOX1 ADAM18 BLNK

3.33e-0594864517e9762e5362b6ff48f0918468a70b736f4d0de
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.36e-051908659ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|343B / Donor, Lineage, Cell class and subclass (all cells)

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.36e-05190865169e600e95878000acf5d11f813f9028c7249646
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.36e-051908650cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.36e-05190865833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCelltumor_Lung-Fibroblasts-Mesothelial_cells|Fibroblasts / Location, Cell class and cell subclass

GALNT14 DSC3 BCO2 DSG2 PRG4

3.36e-05190865d82ab67735c1f365d4b0e02b5fa91c64cdc234da
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNASEL DSG2 PHF3 PDS5A SLC4A4

3.45e-0519186560c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellfacs-Pancreas|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK8IP1 DYNC2H1 ROBO2 CTNND2 IDS

3.45e-05191865d48e5f67d384226add7d7fb2a124954136e09a82
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

P4HB MYDGF APOBEC3B DDOST PRDM1

3.45e-051918657b4b5d90d1023d03239ed986f273afa734d3124d
ToppCellControl-Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

P4HB MYDGF APOBEC3B DDOST PRDM1

3.45e-051918653df5bbdb29bbcbcb8476fdf126b6d4c1ac67d64b
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNASEL DSG2 PHF3 PDS5A SLC4A4

3.45e-0519186509db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNASEL DSG2 PHF3 PDS5A SLC4A4

3.45e-05191865973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellmulticiliated|World / shred by cell class for turbinate

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.54e-051928650f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.54e-05192865d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.54e-05192865354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN TENM1 ROBO2 PRDM1

3.62e-05193865d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.62e-05193865e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN TENM1 ROBO2 PRDM1

3.62e-05193865010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCellfacs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT14 MAPK8IP1 HOXD8 FOXP1 ADAMTSL4

3.62e-05193865eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN TENM1 ROBO2 PRDM1

3.62e-051938652189da4b727e25e62669d7b9257f06493be21a27
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN TENM1 ROBO2 PRDM1

3.62e-051938653ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN TENM1 ROBO2 PRDM1

3.62e-05193865e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN TENM1 ROBO2 PRDM1

3.62e-05193865658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCellASK440-Epithelial-Ciliated|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.62e-05193865a0baa8be6f590b2031fede22be588715ae458e93
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPK8IP1 SPATA17 CFAP300 SPAG17 DNAH7

3.71e-051948653cd90d01ed5a5ce65aad8284dab2537ec16e3d7c
ToppCellASK440-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.71e-05194865c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCellsevere-Plasmablast|World / disease stage, cell group and cell class

P4HB MYDGF APOBEC3B DDOST PRDM1

3.71e-0519486549e8f90db571a89b8a26aef31fcacd66429fed11
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

P4HB MYDGF DEPDC1B APOBEC3B DDOST

3.71e-05194865ffba703f61faaac8b4b9a5e46cd335214303de7b
ToppCellBL-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPRG DSC3 CLCA2 DSG2 SLC4A4

3.71e-051948652932f704656ca368565ec12f3452af3b18e8df12
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.71e-05194865b4ce60c06568123008b1081d644733cb91c28f51
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.71e-051948651ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDS5B HIVEP2 BLNK PDS5A FOXP1

3.71e-051948658ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.71e-05194865958e648138676d46698090b4046cb484083ae449
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.71e-051948657a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 RELN TENM1 ROBO2 PRDM1

3.71e-051948651bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.71e-05194865a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.81e-05195865d8bf15aa7cdbc5f29b58e1e6cff76c257f0ea12e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.81e-051958650e763f36786515698b593e5c93f6a56619c1242d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.81e-05195865581b04220587e1d5198b1abd6965965ace7803e7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.81e-0519586593b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPK8IP1 SPATA17 BCO2 SPAG17 DNAH7

3.81e-0519586579dc031258579ea328181dda33710dd897f1064a
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPK8IP1 SPATA17 CFAP300 SPAG17 DNAH7

3.81e-05195865db4270c135c392ed443670981656e3cd5b95939d
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.81e-0519586534e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPK8IP1 SPATA17 CFAP300 SPAG17 DNAH7

3.81e-051958656365e3893e38231090ec2dbef010dec71dea3d07
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.81e-051958659651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.81e-0519586507a6bcef6af93ed87df455dee624037cb75e011a
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.81e-05195865e7f069f557a59ee7b502ff82ad4c9f47fa619ba8
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KY RELN DYNC2H1 ROBO2 GRIN2C

3.81e-051958657796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.90e-0519686527b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

3.90e-05196865d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

4.00e-051978656865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellSevere|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

P4HB MYDGF APOBEC3B DDOST PRDM1

4.00e-05197865df3f58b58f82c42c65b0a09c054b669b34502037
ToppCellILEUM-inflamed-(5)_Plasmablasts|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

P4HB MYDGF DEPDC1B APOBEC3B DDOST

4.00e-051978658710a586fc91cf664032a12e4d2a0399b370cbcb
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

4.00e-05197865e453d085182364ca347cbcc9dc995c62c3353016
ToppCellCOVID_vent-Lymphocytic-Plasma_cell-IgA_Plasmablast|COVID_vent / Disease condition, Lineage, Cell class and subclass

P4HB BLNK MYDGF DDOST PRDM1

4.00e-0519786599fe44ef42c65d24fe64947fd5bf6d91b9a4b2c3
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

P4HB MYDGF DEPDC1B APOBEC3B DDOST

4.00e-051978656fe013f98c64b3c5a4e61002254717fb411f8e59
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

4.00e-05197865d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellB_cells-Plasmablasts|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

P4HB MYDGF HMCES DDOST PRDM1

4.09e-05198865c6cab47885be74a64351f843a741dea6d911bde4
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HIVEP2 OLFM1 GRIN2A GRIN2B IDS

4.09e-05198865c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPATA17 CFAP300 DYNC2H1 SPAG17 DNAH7

4.09e-05198865ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OLFM1 ROBO2 GRIN2A GRIN2B IDS

4.09e-051988650ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellParenchyma_COVID-19-Endothelial-TX-Lymphatic|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

GABRE RELN PTPRB HOXD8 GRIN2B

4.19e-0519986588f33b8dcd837abfa1d12c28719e073a7da6e979
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 DSC3 COPA P4HB ELK4

4.19e-051998658d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Lymphatic|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GABRE RELN PTPRB HOXD8 GRIN2B

4.19e-0519986564b19aff72e2a109cb5857cb248bd4712dd49b43
ToppCellTransverse-(2)_B_cell-(20)_B_cell_IgA_Plasma|Transverse / shred on region, Cell_type, and subtype

P4HB BLNK MYDGF DDOST PRDM1

4.19e-051998658caaa08b046f766af298d03961ccac6e4569e2a6
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Lymphatic-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GABRE RELN PTPRB HOXD8 GRIN2B

4.19e-051998652b9e1e069b36b3a61cc3e384f4523687b0e03905
ToppCellTransverse-B_cell-B_cell_IgA_Plasma|Transverse / Region, Cell class and subclass

P4HB BLNK MYDGF DDOST PRDM1

4.19e-05199865ea65cadaf464ff4c1040fceb5f3724706f8447c1
Drugconotoxin GV

GRIN2A GRIN2B GRIN2C

5.02e-083853ctd:C055407
DrugAgmatine

GRIN2A GRIN2B GRIN2C NOS2

1.26e-0713854ctd:D000376
DrugDPCPX

PTPRB GRIN2A GRIN2B GRIN2C SLC4A4 PAF1 NOS2

2.80e-07117857CID000001329
DrugNSC221991

DECR1 OLFM1 GRIN2A GRIN2B GRIN2C SLCO1B1

2.90e-0772856CID000004580
Drugmetaphit

P4HB GRIN2A GRIN2B GRIN2C

3.18e-0716854CID000114745
Drug5-(alpha-methyl-4-bromobenzylamino)phosphonomethyl-1,4-dihydroquinoxaline-2,3-dione

GRIN2A GRIN2B GRIN2C

4.99e-075853ctd:C498554
Drug2-Aminoadipic Acid

GRIN2A GRIN2B GRIN2C

4.99e-075853ctd:D015074
Drug(2S*,3R*)-1-(biphenyl-4-carbonyl)piperazine-2,3-dicarboxylic acid

GRIN2A GRIN2B GRIN2C

4.99e-075853ctd:C491996
DrugSDZ EAA 494

GRIN2A GRIN2B GRIN2C

4.99e-075853ctd:C065286
DrugQX-314

P4HB GRIN2A GRIN2B GRIN2C AGPS TECTA

6.32e-0782856CID000003925
DrugC22H28N2O4

GRIN2A GRIN2B GRIN2C PAF1

6.72e-0719854CID000065570
DrugMeperidine

GRIN2A GRIN2B GRIN2C

9.96e-076853DB00454
Drug1,5-(diethylamino)piperidine

GRIN2A GRIN2B GRIN2C

9.96e-076853CID000004025
DrugNaphthols

GRIN2A GRIN2B GRIN2C

9.96e-076853ctd:D009284
DrugN(G)-nitro-L-arginine methyl ester

DECR1 NOX1 GRIN2A GRIN2B GRIN2C PAF1 NOS2

1.25e-06146857CID000003864
DrugTenocyclidine

GRIN2A GRIN2B GRIN2C

1.74e-067853DB01520
Drugtetrazol-5-yl)glycine

GRIN2A GRIN2B GRIN2C

1.74e-067853CID000126383
Drug3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid

GRIN2A GRIN2B GRIN2C

1.74e-067853ctd:C050592
Drughomoquinolinate

GRIN2A GRIN2B GRIN2C

1.74e-067853CID003080554
DrugS)-piperazine-2-carboxylic acid

GRIN2A GRIN2B GRIN2C

1.74e-067853CID001502069
DrugRS)-2-chloro-5-hydroxyphenylglycine

RELN GRIN2A GRIN2B GRIN2C

1.82e-0624854CID003645780
DrugCP-96,345

KY GRIN2A GRIN2B GRIN2C PAF1

1.93e-0655855CID000104943
Drugperzinfotel

GRIN2A GRIN2B GRIN2C

2.77e-068853CID006918236
DrugL-687,414

GRIN2A GRIN2B GRIN2C

2.77e-068853CID000125556
Drug6-chloroquinoxaline-2,3-diol

GRIN2A GRIN2B GRIN2C

2.77e-068853CID000081143
DrugES-242-1

GRIN2A GRIN2B GRIN2C

2.77e-068853CID000131976
DrugSDZ 220-581

GRIN2A GRIN2B GRIN2C

2.77e-068853CID000128019
Drug3alpha5betaHS

GRIN2A GRIN2B GRIN2C

2.77e-068853CID000165024
Drugneramexane

GRIN2A GRIN2B GRIN2C

2.77e-068853CID006433106
Drugpiperazine-2,3-dicarboxylic acid

GRIN2A GRIN2B GRIN2C

2.77e-068853CID000280973
DrugPhenanthrenes

GRIN2A GRIN2B GRIN2C

4.15e-069853ctd:D010616
Drugsodium alpha-oxyhyponitrite

P4HB GRIN2A GRIN2B NOS2

4.60e-0630854CID010129945
Drugpicrotoxin

GABRE CLCA2 P4HB GRIN2A GRIN2B GRIN2C NOS2

5.23e-06181857CID000031304
DrugDCG-IV

SGMS1 P4HB GRIN2A GRIN2B GRIN2C

5.58e-0668855CID000115114
Drugnylidrin

GRIN2A GRIN2B GRIN2C

5.91e-0610853CID000004567
DrugAC1L1ICP

DECR1 GRIN2A GRIN2B

5.91e-0610853CID000004520
DrugEAB 515

GRIN2A GRIN2B GRIN2C

8.11e-0611853CID000159489
Drug5-phosphonopentanoic acid

GRIN2A GRIN2B GRIN2C

8.11e-0611853CID002773807
Drugoxiracetam

GRIN2A GRIN2B GRIN2C

8.11e-0611853CID000004626
Drugo-difluorobenzene

GRIN2A GRIN2B GRIN2C

8.11e-0611853CID000009706
DrugDiphenidol hydrochloride [3254-89-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A

RNASEL NOX1 OLFM1 GAL3ST4 SLC4A4 HS3ST2 SLCO1B1

9.11e-061978577447_UP
Drugpentylenetetrazol

GABRE P4HB GRIN2A GRIN2B GRIN2C IDS

9.33e-06130856CID000005917
Drug3-bromo-7-nitroindazole

GRIN2A GRIN2B GRIN2C NOS2

9.73e-0636854CID000001649
Drugglutamic acid diethyl ester

GRIN2A GRIN2B GRIN2C PAF1

9.73e-0636854CID000073960
DrugCI-1041

GRIN2A GRIN2B GRIN2C

1.08e-0512853CID000156328
Drugtenocyclidine

GRIN2A GRIN2B GRIN2C

1.08e-0512853CID000062751
DrugGAMs

KY GRIN2A GRIN2B GRIN2C

1.21e-0538854CID000002935
DrugDETC-MeSO

DECR1 GRIN2A GRIN2B GRIN2C

1.35e-0539854CID003035711
DrugGCV-MP

POLA1 GRIN2A GRIN2B GRIN2C

1.35e-0539854CID000146785
DrugNSC-72942

DECR1 NOS2

1.38e-052852CID000130797
Drug1,10-diaminodecane

GRIN2A GRIN2B GRIN2C

1.40e-0513853CID000001317
Drugbutanol

DECR1 GRIN2A GRIN2B GRIN2C NOS2 PLA2G15

1.54e-05142856CID000000263
DrugL000369

SGMS1 GRIN2A GRIN2B GRIN2C

1.65e-0541854CID003931705
Drugremacemide

GRIN2A GRIN2B GRIN2C

1.77e-0514853CID000060510
DrugLY341495

SGMS1 GRIN2A GRIN2B GRIN2C

2.00e-0543854CID006324636
DrugACEA-1011

GRIN2A GRIN2B GRIN2C

2.21e-0515853CID000127872
Drugthiokynurenic acid

GRIN2A GRIN2B GRIN2C

2.21e-0515853CID003035667
Drugaurintricarboxylic acid

RNASEL GRIN2A GRIN2B GRIN2C DNASE2

2.33e-0591855CID000002259
Drug7-chlorokynurenic acid

KY GRIN2A GRIN2B GRIN2C

2.40e-0545854CID000001884
Drugoriens

RELN GRIN2A GRIN2B GRIN2C AGPS TECTA

2.45e-05154856CID000161645
Drugargiopine

GRIN2A GRIN2B GRIN2C

2.72e-0516853CID000122294
Drug3,4,7,8-tetrahydroquinoline

GRIN2A GRIN2B GRIN2C

2.72e-0516853CID000094356
DrugLY233536

GRIN2A GRIN2B GRIN2C

2.72e-0516853CID000126239
DrugNaCN

DECR1 GRIN2A GRIN2B GRIN2C

2.85e-0547854CID000008929
DrugPRE-084

GRIN2A GRIN2B GRIN2C

3.29e-0517853CID000126402
Drug7-Cl-Thio-Kyna

GRIN2A GRIN2B GRIN2C

3.29e-0517853CID003035668
DrugADCI

GRIN2A GRIN2B GRIN2C

3.29e-0517853CID000130099
DrugAC1L1FA8

GRIN2A GRIN2B GRIN2C TECTA

3.65e-0550854CID000003150
Drugphenylpropionic acid

BLNK GRIN2A GRIN2B GRIN2C SLC4A4 DNASE2

3.86e-05167856CID000000107
Drug3-hydroxyglutaric acid

GRIN2A GRIN2B GRIN2C

3.93e-0518853CID000181976
DrugMNQX

GRIN2A GRIN2B GRIN2C

3.93e-0518853CID000130818
DrugAC1O3MDH

NOX1 GRIN2A GRIN2B GRIN2C NOS2

4.04e-05102855CID006332158
DrugFelbamate

GRIN2A GRIN2B

4.12e-053852DB00949
DrugSG-86

DECR1 PAF1

4.12e-053852CID000072663
DrugAC1MPBWG

DECR1 POLA1

4.12e-053852CID003382771
DrugQuinoxaline

GRIN2A GRIN2B GRIN2C SPAG17

4.27e-0552854CID000007045
Drugpropanol

DECR1 GRIN2A GRIN2B GRIN2C

4.61e-0553854CID000001031
Drugdonepezil

GRIN2A GRIN2B GRIN2C AGPS

4.61e-0553854CID000003152
Drugarcaine

GRIN2A GRIN2B GRIN2C

4.66e-0519853CID000002227
Drugkynurenine

DECR1 MYDGF GRIN2A GRIN2B GRIN2C

5.31e-05108855CID000000846
DrugIDRA 21

GRIN2A GRIN2B GRIN2C

5.47e-0520853CID000003688
Drugginsenoside Rc

GRIN2A GRIN2B GRIN2C

5.47e-0520853CID000100018
Drugnorethisterone oenanthate

RELN PSEN2 GRIN2A GRIN2B GRIN2C

5.55e-05109855CID000019688
Drugorphenadrine

DECR1 GRIN2A GRIN2B GRIN2C

5.73e-0556854CID000004601
Drugtrifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A

LPIN1 SGMS1 TCN1 TLR1 BLNK OLFM1

5.86e-051808565584_UP
DrugNSC624746

GRIN2A GRIN2B GRIN2C TECTA

6.15e-0557854CID000107640
Drugcarbetapentane

GRIN2A GRIN2B GRIN2C

6.36e-0521853CID000002562
Drugdinor

DECR1 OLFM1 NOS2

6.36e-0521853CID000132460
DrugSulfur Dioxide

DSG2 GRIN2A GRIN2B NOS2

6.58e-0558854ctd:D013458
Drughydroxybutyrate

DECR1 GABRE GRIN2A GRIN2B GRIN2C

7.16e-05115855CID000010413
DrugNS 102

GRIN2A GRIN2B GRIN2C

7.35e-0522853CID005282252
DrugCX516

GRIN2A GRIN2B GRIN2C

7.35e-0522853CID000148184
Drugmethadone

GRIN2A GRIN2B GRIN2C NOS2

7.52e-0560854CID000004095
Drug8-OH-DPAT

GRIN2A GRIN2B GRIN2C PAF1 NOS2

7.77e-05117855CID000001220
Drugpropofol

GABRE COPA GRIN2A GRIN2B GRIN2C NOS2

8.13e-05191856CID000004943
DrugPoly C

GRIN2A GRIN2C

8.22e-054852ctd:D011066
Drugn-propylbenzene

GRIN2A GRIN2B

8.22e-054852ctd:C024268
Drugisoflurane

DECR1 GABRE COPA GRIN2A GRIN2B GRIN2C NOS2

8.41e-05279857CID000003763
Drugpotassium cyanide

DECR1 GRIN2A GRIN2B GRIN2C SPAG17

8.42e-05119855CID000009032
DrugAC1L1ICD

GRIN2A GRIN2B NOS2

8.43e-0523853CID000004516
Diseasepulmonary edema (biomarker_via_orthology)

SGMS1 NOS2

4.45e-054812DOID:11396 (biomarker_via_orthology)
Diseaseschizophrenia (is_implicated_in)

FOXP1 GRIN2A GRIN2B CTNND2

6.44e-0578814DOID:5419 (is_implicated_in)
DiseaseX-21471 measurement

DNMBP SLCO1B1

1.11e-046812EFO_0800818
Diseaseglycocholenate sulfate measurement

DNMBP SLCO1B1

1.11e-046812EFO_0800276
DiseaseAutoinflammatory disorder

COPA POLA1 DNASE2

1.22e-0435813C3860213
Diseaseplacental insufficiency (biomarker_via_orthology)

GRIN2A GRIN2B

2.06e-048812DOID:3891 (biomarker_via_orthology)
Diseasecognitive disorder (biomarker_via_orthology)

GRIN2A GRIN2B

2.06e-048812DOID:1561 (biomarker_via_orthology)
DiseaseX-21467 measurement

DNMBP SLCO1B1

2.65e-049812EFO_0020007
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GRIN2A GRIN2B GRIN2C

3.35e-0449813DOID:0060037 (implicated_via_orthology)
Diseasehyperhomocysteinemia (implicated_via_orthology)

GRIN2A GRIN2B

4.03e-0411812DOID:9279 (implicated_via_orthology)
Diseasevascular dementia (is_marker_for)

GRIN2A GRIN2B

4.03e-0411812DOID:8725 (is_marker_for)
Diseasefactor VII activating protease measurement

USP32 TSPYL5 PRDM1

4.72e-0455813EFO_0009368
Diseaseresponse to vaccine, cytokine measurement

BCO2 TENM1 GRIN2B SLC4A4

4.74e-04131814EFO_0004645, EFO_0004873
DiseaseAlzheimer's disease (implicated_via_orthology)

HIVEP2 PSEN2 NOS2

5.24e-0457813DOID:10652 (implicated_via_orthology)
DiseaseX-21470 measurement

DNMBP SLCO1B1

6.63e-0414812EFO_0800817
DiseaseMental Depression

RELN GRIN2A GRIN2B PFKFB3 NOS2

6.83e-04254815C0011570
DiseaseAutistic Disorder

RELN ROBO2 GRIN2A GRIN2B NOS2

7.72e-04261815C0004352
Diseaseepilepsy (implicated_via_orthology)

GRIN2A GRIN2B GRIN2C NOS2

1.07e-03163814DOID:1826 (implicated_via_orthology)
Diseasetemporal lobe epilepsy (is_marker_for)

RELN GRIN2B

1.37e-0320812DOID:3328 (is_marker_for)
DiseaseHbA1c measurement, response to sulfonylurea

GRIN2A SLCO1B1

1.51e-0321812EFO_0004541, EFO_0007922
DiseaseAutism Spectrum Disorders

RELN FOXP1 GRIN2B

1.67e-0385813C1510586
DiseaseHuntington's disease (is_implicated_in)

GRIN2A GRIN2B

1.81e-0323812DOID:12858 (is_implicated_in)
DiseaseIntrahepatic Cholangiocarcinoma

ROBO2 NOS2

1.98e-0324812C0345905
DiseaseExtrahepatic Cholangiocarcinoma

ROBO2 NOS2

1.98e-0324812C3805278
Diseaserefractive error

GALNT14 GRIN2A GRIN2B AGPS PLA2G15

2.06e-03326815MONDO_0004892
DiseaseTEMPS-A questionnaire

DYNC2H1 SLC4A4

2.14e-0325812EFO_0004783
DiseaseCholangiocarcinoma

ROBO2 NOS2

2.32e-0326812C0206698
DiseaseAbnormality of refraction

GALNT14 SMG1 FOXP1 GRIN2A GRIN2B CTNND2 SLC4A4

2.52e-03673817HP_0000539
Diseaseamino acid measurement

SETX PTPRB ALMS1 ACAD11 PTPRG GRIN2B DNAH7

2.62e-03678817EFO_0005134
DiseaseBarrett's esophagus

FOXP1 GRIN2B

2.69e-0328812EFO_0000280

Protein segments in the cluster

PeptideGeneStartEntry
PGVFTDIEQYQFIYK

PTPRG

1391

P23470
FQEENPGVFYQYVIS

ADAMTSL4

586

Q6UY14
DTGVFRGQVYFKPQY

APOBEC3B

51

Q9UH17
GKQSFLPQNFLVYTY

ADAM18

61

Q9Y3Q7
FYSQREKPGIFYQQT

ALMS1

1096

Q8TCU4
FYSQREKPGIFYQQT

ALMS1

1191

Q8TCU4
YSFGEKPIVNYKQAF

ALMS1

1571

Q8TCU4
QFQKSYPEVYQERFP

DEPDC1B

476

Q8WUY9
QVYFAVYTFKARNPN

DNMBP

1516

Q6XZF7
GRYYSKPFVTFHQIN

BCO2

346

Q9BYV7
RKDYETYQPFQNSTR

CTNND2

1151

Q9UQB3
PTFYLQKGFQTYVLR

ACAD11

56

Q709F0
GLEDTKSPQFNRYFY

PDS5B

116

Q9NTI5
PTINYTLRDYRKFFQ

PLA2G15

286

Q8NCC3
GLEDTKSPQFNRYFY

PDS5A

126

Q29RF7
ISTFGYNRNNKKPYV

RBMS2

11

Q15434
RKNTNEFYKTIPRFY

PPP2R3C

46

Q969Q6
KLPDFESRYVQNGTY

DSG2

451

Q14126
PQAIEFVNQYYGSFK

NOS2

141

P35228
RYSSLDPRKVQFYFN

NOX1

546

Q9Y5S8
PYNIKFYETVGQDFR

HS3ST2

351

Q9Y278
FNPYNNRKSEGRIVY

PTPRB

1306

P23467
FYGYDNLQRQPIFTT

HOXD8

136

P13378
FQQFYKQFVEYTCPT

MAPK8IP1

691

Q9UQF2
KRQEPGNYIFVFNYL

KY

541

Q8NBH2
KIQRTYFYSSNNEQP

FSIP2

3721

Q5CZC0
TGQVVYNGSIYFNKF

OLFM1

301

Q99784
REAVKQYSSYNFFRP

PFKFB3

76

Q16875
GNETSSDYYNFQKPR

GAPT

126

Q8N292
QEFYKNAEVRPPFTY

FOXP1

456

Q9H334
GVYIFQPVFEQYAKD

PIGBOS1

21

A0A0B4J2F0
AAFGNRPADVYSYKQ

LPIN1

796

Q14693
PDTQYYFDVFVVNIN

NDNF

306

Q8TB73
RFGYVAFQNYVPSSV

GABRE

276

P78334
AQQYGVRGYPTIKFF

P4HB

91

P07237
LPDVYGVFQFKVDYN

DDOST

381

P39656
ARYQFGYPKLFQASR

GAL3ST4

101

Q96RP7
FYENNYIVPDKQIFR

POLA1

796

P09884
FPYFLVRFTVIYNEQ

METTL7A

36

Q9H8H3
EIFYDQYSKPGFVNI

RELN

2611

P78509
YVFPDGNANTYIKNT

GALNT14

341

Q96FL9
YPFDQNRFVQYKATS

PAF1

51

Q8N7H5
PRRFFSYGTKILYQN

DECR1

21

Q16698
GYYFRFLPQKTFQSL

CFAP300

11

Q9BRQ4
FGPVFNYFTYRIQQN

DYNC2H1

2761

Q8NCM8
QNPDKLRFNFYTSQY

GUCA1ANB

71

X6R8D5
QPYTLVVFFNKRVYN

BLNK

381

Q8WV28
VKQEFQPSQSYRYGN

C6orf52

31

Q5T4I8
VYNYQLEGIFAQEFP

DNASE2

181

O00115
SYQKNAGFQEYTIPI

DSC3

636

Q14574
NGQKFVYKFVSYPEI

ELK4

76

P28324
QFGPYKQLFLQTYAR

COPA

951

P53621
KSFFVELQRYNYVTP

DNAH7

2546

Q8WXX0
QRPFVFNYYENVLEK

FAM172BP

36

A6NC97
QYPLKQYRESQAFSF

EME2

256

A4GXA9
FSTIPQYFKENGYVT

IDS

116

P22304
QRQPYFIYFPQIKTE

HMCES

136

Q96FZ2
NQYYFRNSVVDPFRK

SPATA17

16

Q96L03
FVALTKGQYPVFNQY

TBC1D31

666

Q96DN5
QSPEPENRFIQYFYN

LMBRD2

356

Q68DH5
VPYENSVRQFLGEYK

SMG1

3446

Q96Q15
KPYEGESSYIIFQQF

MEP1A

111

Q16819
KFYEKRGNFYQNTVG

RNASEL

646

Q05823
GTVYQKYEPIFFQSI

SETD9

156

Q8NE22
NFYQLQVRKFPADYI

SETX

1771

Q7Z333
YSFENNYPVGKIQDV

TENM1

2406

Q9UKZ4
YTNDTVPKNANRKYF

PRDM1

121

O75626
FFKRGGSIQQYIYKQ

PRG4

1261

Q92954
FTYVFKYVEQQYGQP

SLCO1B1

356

Q9Y6L6
ESSSNIYYPFQKREQ

SPAG17

1551

Q6Q759
QVVSDVFGFPQSYIY

TLR1

306

Q15399
EYQKYGSVAFPNFEQ

AGPS

386

O00116
FDPDGRKYYTNNFIT

CLCA2

541

Q9UQC9
TVNEIYKQYFKSNFP

RIDA

91

P52758
FFFGVPYRTVYVNNN

TECTA

56

O75443
VFQKYVPSFSGYSQQ

USP21

286

Q9UK80
EKSFYQFQHYRAIPG

MTREX

586

P42285
TPENKNYYFGSQFSV

TCN1

171

P20061
SRYIGPQNFYQVKDI

PHF3

1876

Q92576
FYTEKNGQLIYTPFT

PSEN2

111

P49810
YRPFQYFEKNVQGIV

SGMS1

371

Q86VZ5
VTYEIKVRPYFNEFQ

ROBO2

706

Q9HCK4
YPINSNFKVGYNTLF

SLC4A4

611

Q9Y6R1
YSPETFRQQFRQFGY

ZNF396

46

Q96N95
FLNYTKPNYVQQATF

HIVEP2

1651

P31629
YQYPFTLRVVQKDGN

USP32

1151

Q8NFA0
FYFDRNPYFQNKVLI

TSPYL5

296

Q86VY4
RPQGKSYLYFTQFKA

MYDGF

96

Q969H8
FEYFSPVGYNRNLAK

GRIN2A

576

Q12879
IVTTYFPGYQDFVNK

GRIN2B

171

Q13224
YFSPVSYNQNLTRGK

GRIN2C

576

Q14957