Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	3.56e-06	5	143	3	GO:0030156
GeneOntologyCellularComponent	stereocilium	DOCK4 WHRN RIPOR2 TPRN PKHD1L1	1.18e-04	69	145	5	GO:0032420
GeneOntologyCellularComponent	stereocilium bundle	DOCK4 WHRN RIPOR2 TPRN PKHD1L1	2.24e-04	79	145	5	GO:0032421
Domain	SH3_2	DOCK3 DOCK4 RUSC2 RIMBP3 RIMBP3C RIMBP3B	5.36e-05	86	144	6	PF07653
Domain	SH3_2	DOCK3 DOCK4 RUSC2 RIMBP3 RIMBP3C RIMBP3B	5.36e-05	86	144	6	IPR011511
Domain	FAM53	FAM53C FAM53B	1.76e-04	3	144	2	IPR029356
Domain	FAM53	FAM53C FAM53B	1.76e-04	3	144	2	PF15242
Domain	Growth_fac_rcpt_	TNFRSF9 KRT83 SVEP1 BMP1 SLIT1 SCUBE3 PCSK4	2.09e-04	156	144	7	IPR009030
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DOCK4 JCAD UBAP2 TTC28 SEC24A SIK3 MLXIP PRAG1 FAM53C NEK9 RUSC2 IVNS1ABP PLEKHG1 MLXIPL PHLDB1 TBC1D4 NF1 NHS FAM53B CAMSAP2 PHLDB2	1.43e-10	861	149	21	36931259
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	WHRN ANKS6 CHIA CTTNBP2 MTHFD1L KRT81 KRT83 SEC24A SIK3 ANKRD6 NEK9 CYFIP2 GPR107 NUTM2E PLEKHG1 TRAFD1 NF1 HECW2 ARID2 USP4 POLD3 CCDC24 ZRANB1 PEAR1	6.81e-10	1242	149	24	30973865
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK4 WHRN RIPOR2 TTC28 FRMPD1 TNRC6C MLXIP RUSC2 PLEKHG1 PHLDB1 SUGP2 SLIT1 CAMSAP2 ULK2	2.81e-09	407	149	14	12693553
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DOCK3 ANKS6 MTHFD1L ADGRB2 POLRMT TNRC6C ITGA3 MLXIP ARHGAP35 PRAG1 RNF43 MAPK8IP3 PLEKHG1 NCOR2 PHLDB1 MAP1S SUGP2 PXN ULK2	2.91e-07	1105	149	19	35748872
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	3.07e-07	4	149	3	19091768
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	ANKS6 HDAC6 ACD SEC24A TNRC6C MLXIP FAM53C NEK9 HEXIM2 RUSC2 MLXIPL PHLDB1 TRAFD1 FBXO9 PXN FAM53B POLD3 CAMSAP2	5.43e-07	1038	149	18	26673895
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	7.66e-07	5	149	3	17855024
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	HDAC6 ARHGAP35 FAM53C HEXIM2 C2CD5 MAPK8IP3 NCOR2 EIF2D TBC1D4 TRAFD1 NF1 MAP1S SUGP2 TP53BP1 PHLDB2	1.32e-06	774	149	15	15302935
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP36 HDAC6 TTC28 TPRN POLRMT SIK3 ITGA3 SP110 FAM53C RNF43 C2CD5 NCOR2 SALL2 TRAFD1 SUGP2 ARID2 ZFHX3 PHLDB2	1.52e-06	1116	149	18	31753913
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	JCAD CTTNBP2 HDAC6 TTC28 CYFIP2 C2CD5 PLEKHG1 TBC1D4 NF1 MAP1S PHLDB2	3.86e-06	446	149	11	24255178
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DOCK4 JCAD TTC28 MTHFD1L SEC24A SHB CTIF TNRC6C SIK3 MLXIP RIMBP3 PLEKHG1 EIF2D PXN CAMSAP2	4.30e-06	853	149	15	28718761
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TTC28 SCRN1 TNRC6C SIK3 ARHGAP35 PHLDB1 SALL2 SLIT1	6.17e-06	225	149	8	12168954
Pubmed	Laminin-based cell adhesion anchors microtubule plus ends to the epithelial cell basal cortex through LL5alpha/beta.	PHLDB1 PHLDB2	1.82e-05	2	149	2	20513769
Pubmed	Glucose-dependent transcriptional regulation by an evolutionarily conserved glucose-sensing module.	MLXIP MLXIPL	1.82e-05	2	149	2	16644671
Pubmed	Paxillin/HDAC6 regulates microtubule acetylation to promote directional migration of keratinocytes driven by electric fields.	HDAC6 PXN	1.82e-05	2	149	2	37949303
Pubmed	USP36-Mediated Deubiquitination of DOCK4 Contributes to the Diabetic Renal Tubular Epithelial Cell Injury via Wnt/β-Catenin Signaling Pathway.	USP36 DOCK4	1.82e-05	2	149	2	33968925
Pubmed	Contrasting Patterns in the Evolution of Vertebrate MLX Interacting Protein (MLXIP) and MLX Interacting Protein-Like (MLXIPL) Genes.	MLXIP MLXIPL	1.82e-05	2	149	2	26910886
Pubmed	Impaired protein stability and nuclear localization of NOBOX variants associated with premature ovarian insufficiency.	FOXL2 NOBOX	1.82e-05	2	149	2	27798098
Pubmed	Paxillin inhibits HDAC6 to regulate microtubule acetylation, Golgi structure, and polarized migration.	HDAC6 PXN	1.82e-05	2	149	2	25070956
Pubmed	MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic β-Cells.	MLXIP MLXIPL	1.82e-05	2	149	2	29282201
Pubmed	FAM65B controls the proliferation of transformed and primary T cells.	RIPOR2 HDAC6	1.82e-05	2	149	2	27556504
Pubmed	Interaction of the Akt substrate, AS160, with the glucose transporter 4 vesicle marker protein, insulin-regulated aminopeptidase.	TBC1D4 LNPEP	1.82e-05	2	149	2	16762977
Pubmed	NOBOX is a key FOXL2 partner involved in ovarian folliculogenesis.	FOXL2 NOBOX	1.82e-05	2	149	2	24620032
Pubmed	Brain-specific angiogenesis inhibitor 2 (BAI2) may be activated by proteolytic processing.	ADGRB2 NFATC2	1.82e-05	2	149	2	20367554
Pubmed	Identification of a cellular ligand for the natural cytotoxicity receptor NKp44.	KMT2E NCR2	1.82e-05	2	149	2	23958951
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B	2.71e-05	14	149	3	17662146
Pubmed	Comprehensive analysis of keratin gene clusters in humans and rodents.	KRT81 KRT83 KRT39	4.14e-05	16	149	3	15085952
Pubmed	Activation of Th2 cells downregulates CRTh2 through an NFAT1 mediated mechanism.	NFATC2 PTGDR2	5.45e-05	3	149	2	29969451
Pubmed	Structure and site of expression of a murine type II hair keratin.	KRT81 KRT83	5.45e-05	3	149	2	1372089
Pubmed	Transient expression of mouse hair keratins in transfected HeLa cells: interactions between "hard" and "soft" keratins.	KRT81 KRT83	5.45e-05	3	149	2	1712823
Pubmed	TXNIP induced by MondoA, rather than ChREBP, suppresses cervical cancer cell proliferation, migration and invasion.	MLXIP MLXIPL	5.45e-05	3	149	2	31782782
Pubmed	Faster regeneration associated to high expression of Fam65b and Hdac6 in dysferlin-deficient mouse.	RIPOR2 HDAC6	5.45e-05	3	149	2	31218594
Pubmed	Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation.	TBC1D4 LNPEP	5.45e-05	3	149	2	30257216
Pubmed	An ULK1/2-PXN mechanotransduction pathway suppresses breast cancer cell migration.	PXN ULK2	5.45e-05	3	149	2	37846507
Pubmed	Novel KRT83 and KRT86 mutations associated with monilethrix.	KRT81 KRT83	5.45e-05	3	149	2	25557232
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK3 CTTNBP2 CTIF ARHGAP35 ANKRD6 NEK9 C2CD5 PWWP2A TTBK1 ARID2	5.64e-05	493	149	10	15368895
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	DOCK3 RIPOR2 RUSC2 SALL2 SUGP2	8.82e-05	104	149	5	9205841
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	DOCK3 JCAD UBAP2 KMT2E NEK9 NCOR2 MAP1S MAP4K5 ARID2	1.06e-04	430	149	9	35044719
Pubmed	Deafness-Associated ADGRV1 Mutation Impairs USH2A Stability through Improper Phosphorylation of WHRN and WDSUB1 Recruitment.	WHRN WDSUB1	1.09e-04	4	149	2	37066759
Pubmed	Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.	NF1 SCN9A	1.09e-04	4	149	2	22260870
Pubmed	TRABID overexpression enables synthetic lethality to PARP inhibitor via prolonging 53BP1 retention at double-strand breaks.	ZRANB1 TP53BP1	1.09e-04	4	149	2	37002234
Pubmed	Liprin-α1, ERC1 and LL5 define polarized and dynamic structures that are implicated in cell migration.	PHLDB1 PHLDB2	1.09e-04	4	149	2	24982445
Pubmed	Keratins of the human hair follicle.	KRT81 KRT83	1.09e-04	4	149	2	15797458
Pubmed	Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.	RIPOR2 TPRN	1.09e-04	4	149	2	27269051
Pubmed	Analysis of BCL6-interacting proteins by tandem mass spectrometry.	ARHGAP35 MAPK8IP3 NCOR2 POU2F3	1.49e-04	62	149	4	16147992
Pubmed	A census of human transcription factors: function, expression and evolution.	MLXIP SP110 MLXIPL SALL2 NEUROG1 FOXL2 HOXD3 NFATC2 DMRTC2 ZFHX3 POU2F3 TCFL5 NOBOX	1.54e-04	908	149	13	19274049
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	PAG1 SIK3 PRAG1 NEK9 HEXIM2 CYFIP2 C2CD5 NCOR2 NF1 MAP1S MAP4K5 PXN RNF111	1.57e-04	910	149	13	36736316
Pubmed	Fam65b is important for formation of the HDAC6-dysferlin protein complex during myogenic cell differentiation.	RIPOR2 HDAC6	1.81e-04	5	149	2	24687993
Pubmed	RhoA/ROCK activation by growth hormone abrogates p300/histone deacetylase 6 repression of Stat5-mediated transcription.	HDAC6 ARHGAP35	1.81e-04	5	149	2	15102857
Pubmed	MondoA-Mlx transcriptional activity is limited by mTOR-MondoA interaction.	MLXIP MLXIPL	1.81e-04	5	149	2	25332233
Pubmed	Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex.	PHLDB1 PHLDB2	1.81e-04	5	149	2	23940118
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	WHRN ANKS6 UBAP2 FAM53C NEK9 IVNS1ABP DNAAF2 TBC1D4 TRAFD1 NF1 PXN FAM53B CAMSAP2 HCCS TP53BP1 PHLDB2	1.83e-04	1321	149	16	27173435
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	USP36 KRT83 SEC24A ARHGAP35 DNAAF2 SUGP2 ARID2 PXN TP53BP1	2.11e-04	472	149	9	38943005
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	WHRN EPSTI1 ACD TPRN SCRN1 VSIG10 SP110 PKHD1L1 PLEKHG1 SLIT1 FAM53B TCFL5	2.13e-04	814	149	12	23251661
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	DOCK4 TTC28 TPRN NOSIP RIMBP3 NCOR2 SALL2 TBC1D4 ARID2 TP53BP1	2.37e-04	588	149	10	38580884
Pubmed	Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.	ARMC9 TNRC6C PHLDB1 ZFHX3	2.52e-04	71	149	4	23400010
Pubmed	POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination.	ACD TP53BP1	2.70e-04	6	149	2	17053789
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CTTNBP2 UBAP2 ADGRB2 SIK3 NEK9 CYFIP2 MAPK8IP3 NOSIP NCOR2 NF1 CAMSAP2 TP53BP1 PHLDB2	2.72e-04	963	149	13	28671696
Pubmed	Spatiotemporal regulation of GLI target genes in the mammalian limb bud.	WHRN LYPD6 DLK1 SVEP1 NCOR2 HCCS	2.80e-04	207	149	6	26238476
Pubmed	Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.	UBAP2 SHB PRAG1 PXN	3.10e-04	75	149	4	15951569
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	CTTNBP2 POLRMT SUGP2 HECW2 ARID2 ZRANB1	3.18e-04	212	149	6	33853758
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	TENT4B SIK3 KMT2E CAPN13 TTBK1 HECW2 USP4 PLA2G4F PCSK4 BBC3 ULK2	3.26e-04	730	149	11	34857952
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	HDAC6 FRMPD1 POLRMT HEXIM2 CYFIP2 NCOR2 SALL2 TBC1D4 FOXL2 SUGP2 NFATC2 TP53BP1	3.39e-04	857	149	12	25609649
Pubmed	Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides.	SIK3 MLXIPL	3.78e-04	7	149	2	18193046
Pubmed	Integrin α3 is required for late postnatal stability of dendrite arbors, dendritic spines and synapses, and mouse behavior.	ITGA3 ARHGAP35	3.78e-04	7	149	2	23595732
Pubmed	TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling.	ACD TP53BP1	3.78e-04	7	149	2	25344324
Pubmed	Classification and evolutionary analysis of the basic helix-loop-helix gene family in the green anole lizard, Anolis carolinensis.	MLXIP MLXIPL	3.78e-04	7	149	2	23756994
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	DOCK3 DOCK4 JCAD UBAP2 ADGRB2 SCRN1 ARHGAP35 MAPK8IP3 NF1 MAP1S SUGP2 POLD3 CAMSAP2 TP53BP1	4.06e-04	1139	149	14	36417873
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TTC28 POLRMT NEK9 NCOR2 SALL2 TBC1D4 PXN ZFHX3	4.65e-04	418	149	8	34709266
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP36 UBAP2 SCRN1 SIK3 GPR107 IVNS1ABP HECW2 FAM53B ARHGAP20	4.84e-04	529	149	9	14621295
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	PAG1 SHB CYFIP2 C2CD5 PHLDB1 MAP4K5 NHS PHLDB2	4.87e-04	421	149	8	36976175
Pubmed	Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor.	PAG1 PXN	5.02e-04	8	149	2	14665621
Pubmed	Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.	NCOR2 FAM53B	5.02e-04	8	149	2	23958962
Pubmed	Differential expression of HDAC and HAT genes in atrophying skeletal muscle.	PAG1 HDAC6	5.02e-04	8	149	2	26372908
Pubmed	A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.	LYPD6 UBAP2 ACD TTC28 MTHFD1L CTIF C2CD5 RUSC2	5.68e-04	431	149	8	33660365
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	VSIG10 C2CD5 GPR107 NOSIP BMP1 MLXIPL EIF2D NF1 ARID2 NHS BBC3 ULK2 ZRANB1 HCCS PTGDR2	6.02e-04	1327	149	15	32694731
Pubmed	Histone deacetylase 6 (HDAC6) promotes the pro-survival activity of 14-3-3ζ via deacetylation of lysines within the 14-3-3ζ binding pocket.	HDAC6 TBC1D4	6.44e-04	9	149	2	25770209
Pubmed	Usp25m protease regulates ubiquitin-like processing of TUG proteins to control GLUT4 glucose transporter translocation in adipocytes.	TBC1D4 LNPEP	6.44e-04	9	149	2	29773651
Pubmed	Expression and possible roles of extracellular signal-related kinases 1-2 (ERK1-2) in mouse primordial germ cell development.	FOXL2 NOBOX	6.44e-04	9	149	2	32418930
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	USP36 HDAC6 MTHFD1L POLRMT NEK9 NCOR2 EIF2D PHLDB1 TBC1D4 NF1 SUGP2 MAP4K5 POLD3 TP53BP1 PHLDB2	7.33e-04	1353	149	15	29467282
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	RIPOR2 CTTNBP2 PDE7A ZNF689 HEXIM2 MAPK8IP3 NMU PWWP2A NCOR2 NF1 MAP4K5 ARID2 MOCS1 RNF111	7.64e-04	1215	149	14	15146197
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	CHIA CMYA5 PKHD1L1 GPR107 IVNS1ABP SUGP2 HECW2 SCN9A SPATA22 NCR2	7.84e-04	686	149	10	29987050
Pubmed	BCoR, a novel corepressor involved in BCL-6 repression.	HDAC6 NCOR2	8.02e-04	10	149	2	10898795
Pubmed	Maternal vitamin C regulates reprogramming of DNA methylation and germline development.	FOXL2 NOBOX	8.02e-04	10	149	2	31485074
Pubmed	Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors.	ACD MAGEB18 MAPK8IP3 NF1 ARID2 PXN TP53BP1	9.44e-04	359	149	7	35559673
Pubmed	The miR-183/ItgA3 axis is a key regulator of prosensory area during early inner ear development.	ITGA3 BBC3	9.78e-04	11	149	2	28777373
Pubmed	SVEP1 is an endogenous ligand for the orphan receptor PEAR1.	SVEP1 PEAR1	9.78e-04	11	149	2	36792666
Pubmed	Genetic variations strongly influence phenotypic outcome in the mouse retina.	FBXO9 NFATC2 TP53BP1	1.02e-03	46	149	3	21779340
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	USP36 WHRN JCAD UBAP2	1.03e-03	103	149	4	10819331
Pubmed	The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.	FAM53C NF1 LNPEP CAMSAP2	1.15e-03	106	149	4	31024071
Pubmed	TRIM28 functions as a negative regulator of aggresome formation.	HDAC6 CTIF	1.17e-03	12	149	2	33783327
Pubmed	Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain.	KRT81 KRT83	1.17e-03	12	149	2	10692104
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	PAG1 SHB CYFIP2 C2CD5 PHLDB1 NF1 MAP4K5	1.25e-03	377	149	7	38117590
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DOCK3 JCAD HDAC6 PDE7A TTC28 KRT83 ZBTB47 CMYA5 ANKRD6 FAM53C MAPK8IP3 MAP1S CCDC24 RNF111	1.30e-03	1285	149	14	35914814
Pubmed	The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family.	DOCK3 DOCK4	1.38e-03	13	149	2	21930703
Pubmed	FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells.	FOXL2 TP53BP1	1.38e-03	13	149	2	37580696
Pubmed	A type 2 immune circuit in the stomach controls mammalian adaptation to dietary chitin.	CHIA POU2F3	1.38e-03	13	149	2	37676935
Pubmed	MCM8 interacts with DDX5 to promote R-loop resolution.	FOXL2 TP53BP1	1.38e-03	13	149	2	38858601
Pubmed	HectD1 E3 ligase modifies adenomatous polyposis coli (APC) with polyubiquitin to promote the APC-axin interaction.	CTTNBP2 ZRANB1	1.38e-03	13	149	2	23277359
Pubmed	DNA repair protein FANCD2 has both ubiquitination-dependent and ubiquitination-independent functions during germ cell development.	FOXL2 TP53BP1	1.38e-03	13	149	2	36642183
Interaction	YWHAG interactions	DOCK4 JCAD RIPOR2 UBAP2 TTC28 SEC24A SHB SIK3 MLXIP PRAG1 FAM53C CYFIP2 RUSC2 PLEKHG1 MLXIPL PHLDB1 TTBK1 TBC1D4 NF1 NFATC2 MAP4K5 NHS FAM53B CAMSAP2 ZRANB1 PHLDB2	8.56e-07	1248	145	26	int:YWHAG
Interaction	YWHAH interactions	DOCK4 JCAD UBAP2 TTC28 SEC24A SIK3 MLXIP PRAG1 FAM53C CYFIP2 RUSC2 IVNS1ABP PLEKHG1 MLXIPL PHLDB1 TBC1D4 NF1 NHS USP4 FAM53B CAMSAP2 ZRANB1 PHLDB2	3.90e-06	1102	145	23	int:YWHAH
Interaction	YWHAB interactions	DOCK4 PDE7A TTC28 SEC24A SIK3 MLXIP FAM53C RNF43 CYFIP2 RUSC2 IVNS1ABP PHLDB1 TBC1D4 NF1 NFATC2 NHS USP4 FAM53B CAMSAP2 ZRANB1 PHLDB2	1.21e-05	1014	145	21	int:YWHAB
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	JCAD PAG1 PRAG1 RNF43 PLEKHG1 PHLDB1 NHS ZFHX3	2.51e-07	189	149	8	0abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCell	Endothelial-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	JCAD FSTL3 PKHD1L1 PLEKHG1 HOXD3 HECW2 PEAR1	1.88e-06	172	149	7	8a527dff06d841a86c7eb04a1dd9630787294da4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 PDE7A PRAG1 SVEP1 PLEKHG1 NFATC2 NHS	2.93e-06	184	149	7	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	JCAD PAG1 PRAG1 RNF43 PHLDB1 NHS ZFHX3	3.27e-06	187	149	7	387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast-MyoFB-1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	TSSK6 SCRN1 XKR4 SCN9A TCFL5 PTGDR2	9.49e-06	145	149	6	ac41c6c02b7d78162b86222983688f54d04ac47d
ToppCell	3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3\|bone_marrow / Manually curated celltypes from each tissue	KRT81 SCRN1 DLK1 SVEP1 SCN9A PTGDR2	1.11e-05	149	149	6	d7f1069f70f3cad6d3700ee2041ed1d4cb7c49ab
ToppCell	PND07-28-samps-Lymphocyte\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TDRD5 TSSK6 RIPOR2 EPSTI1 MTHFD1L CYFIP2	1.49e-05	157	149	6	105f2711d7bae3be36714954e103c61cf021f957
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PAG1 CMYA5 PRAG1 RNF43 NHS ZFHX3	1.49e-05	157	149	6	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK3 TDRD5 DLK1 PKHD1L1 SCN9A DMBT1	1.78e-05	162	149	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	control-Epithelial-Ionocyte\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DOCK4 HEPACAM2 XKR4 TBC1D4 SCN9A PHLDB2	1.98e-05	165	149	6	5cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCell	control-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DOCK4 HEPACAM2 XKR4 TBC1D4 SCN9A PHLDB2	2.19e-05	168	149	6	327b02f19f4a8607c033203824fdc60a1254331f
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CTTNBP2 KRT81 IVNS1ABP TRAFD1 PLA2G4F BBC3	2.58e-05	173	149	6	0f9c1d3298e59e6d22bb3306f0f445f490be8bbd
ToppCell	droplet-Tongue-nan-24m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATG9B KRT81 KRT83 KRT39 HECW2	2.63e-05	104	149	5	a4ae3cae44aac8b6e0d14896f9acab44f0cc97c4
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte-3\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATG9B GPR27 VSIG10 CAPN13 SCUBE3 PEAR1	2.67e-05	174	149	6	76310c0af1d7df6a4de3816838b2ac2892f68746
ToppCell	Control-B_cells-B_cells\|Control / group, cell type (main and fine annotations)	RIPOR2 PDE7A CR2 SP110 CYFIP2 PLEKHG1	2.84e-05	176	149	6	d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GRIN2C VSIG10 RNF43 SVEP1 TBC1D4 PLA2G4F	2.94e-05	177	149	6	4672cc75225a4a23b298afa8ce439628262519db
ToppCell	COVID-19-B_cells-Activated_B_cells\|COVID-19 / group, cell type (main and fine annotations)	RIPOR2 PDE7A CR2 SP110 CYFIP2 PLEKHG1	2.94e-05	177	149	6	653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCell	T_cells-TFH-like_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	WHRN VSIG10 TTBK1 TBC1D4 NHS FAM53B	3.03e-05	178	149	6	e2ae43e5ec31de6197f2cbd6089f944adbf0a163
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 JCAD SHB PLEKHG1 HECW2 PXN	3.13e-05	179	149	6	8f9e538c822940785130297712b75131812a4603
ToppCell	Children_(3_yrs)-Immune-B_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RIPOR2 CR2 SP110 PRAG1 CYFIP2 PLEKHG1	3.22e-05	180	149	6	40a12eb852373ae3d7c8d9bca376b0ae99f724b3
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD TTC28 KMT2E PLEKHG1 HECW2 PEAR1	3.22e-05	180	149	6	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD TTC28 KMT2E PLEKHG1 HECW2 PEAR1	3.22e-05	180	149	6	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PKHD1L1 PLEKHG1 HECW2 SCN9A PHLDB2 PEAR1	3.33e-05	181	149	6	e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RIPOR2 PDE7A CR2 SP110 CYFIP2 PLEKHG1	3.33e-05	181	149	6	8d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCell	Control-Endothelial-Endothelial-Activated_Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK4 JCAD EPSTI1 PLEKHG1 HECW2 SCN9A	3.54e-05	183	149	6	e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	PKHD1L1 PLEKHG1 HOXD3 HECW2 SCN9A PEAR1	3.76e-05	185	149	6	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHB HEPACAM2 CMYA5 KRT39 ZFHX3 POU2F3	3.76e-05	185	149	6	686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	PKHD1L1 PLEKHG1 HOXD3 HECW2 SCN9A PEAR1	3.76e-05	185	149	6	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PKHD1L1 PLEKHG1 HECW2 SCN9A PHLDB2 PEAR1	3.87e-05	186	149	6	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	Control-Endothelial-Endothelial-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK4 JCAD CTIF PLEKHG1 HECW2 SCN9A	3.99e-05	187	149	6	ea9d34bcd3bd1f36745846309ede349773de501a
ToppCell	CF\|World / Disease state, Lineage and Cell class	DOCK4 RIPOR2 SIK3 CYFIP2 IVNS1ABP PXN	3.99e-05	187	149	6	eec4d4e4a658e3a61c05745167a1a5e3d39bb43e
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PAG1 ADARB2-AS1 PHLDB1 ZFHX3 MOCS1 PEAR1	3.99e-05	187	149	6	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	CTTNBP2 PKHD1L1 PLEKHG1 HOXD3 HECW2 PEAR1	3.99e-05	187	149	6	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	PAG1 SIK3 NF1 LNPEP ARID2 TP53BP1	4.11e-05	188	149	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAG1 CTTNBP2 ADGRB2 CTIF ITGA3 XKR4	4.11e-05	188	149	6	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAG1 CTTNBP2 ADGRB2 CTIF ITGA3 XKR4	4.11e-05	188	149	6	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	TTC28 MTHFD1L ARMC9 SCN9A DMBT1 POU2F3	4.11e-05	188	149	6	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PKHD1L1 PLEKHG1 HOXD3 HECW2 PHLDB2 PEAR1	4.11e-05	188	149	6	aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCell	RA-14._Fibroblast_III\|RA / Chamber and Cluster_Paper	USP36 MTHFD1L SIK3 NCOR2 NFATC2 PHLDB2	4.23e-05	189	149	6	46e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK4 CTTNBP2 CMYA5 SVEP1 SLIT1 ARHGAP20	4.23e-05	189	149	6	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PKHD1L1 PLEKHG1 HOXD3 HECW2 PHLDB2 PEAR1	4.36e-05	190	149	6	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK4 JCAD ITGA3 PLEKHG1 PHLDB1 HECW2	4.36e-05	190	149	6	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	COVID-19-kidney-Stressed_EC\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK4 JCAD PLEKHG1 HECW2 PXN PEAR1	4.49e-05	191	149	6	d35aa842b813ea0eff7362abc894cca4e86b2fb2
ToppCell	Control-Endothelial-Lymphatic\|World / Disease state, Lineage and Cell class	PKHD1L1 PLEKHG1 HOXD3 HECW2 PHLDB2 PEAR1	4.62e-05	192	149	6	f95fb188aa642f3d0618242a770e7c4b70544adb
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHB HEPACAM2 CMYA5 KRT39 DMBT1 POU2F3	4.62e-05	192	149	6	d6ea34391c3f730684b82e912d9cf55e928b3311
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK4 JCAD CTIF PLEKHG1 HECW2 SCN9A	4.76e-05	193	149	6	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial-Lymphatic\|Control / Disease state, Lineage and Cell class	PKHD1L1 PLEKHG1 HOXD3 HECW2 PHLDB2 PEAR1	4.76e-05	193	149	6	64d19be73e5432d491436a01da5de5c926b615a9
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK4 JCAD CTIF PLEKHG1 HECW2 SCN9A	4.76e-05	193	149	6	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK4 IVNS1ABP PLEKHG1 HECW2 PXN PEAR1	4.76e-05	193	149	6	479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell	COVID-19-kidney-Glomerular_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK4 JCAD PKHD1L1 PLEKHG1 HECW2 PXN	4.90e-05	194	149	6	660535b492445063d965095a50e1e299ce04c50a
ToppCell	Adult-Endothelial\|Adult / Lineage, Cell type, age group and donor	JCAD PKHD1L1 PLEKHG1 HOXD3 HECW2 PEAR1	4.90e-05	194	149	6	963b3fbee0575af8379baa397ace65949eaf34f7
ToppCell	Control-Endothelial\|Control / Disease state, Lineage and Cell class	JCAD PKHD1L1 PLEKHG1 HOXD3 HECW2 PEAR1	4.90e-05	194	149	6	485fe5538fabec457b9a51feb641f2a91cbf4e18
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WHRN ITGA3 XKR4 PLEKHG1 LNPEP NHS	5.04e-05	195	149	6	938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	PAG1 TNRC6C KMT2E CYFIP2 NOSIP TBC1D4	5.04e-05	195	149	6	4bdedd924564a260841a9153604026b57487c83d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WHRN ITGA3 XKR4 PLEKHG1 LNPEP NHS	5.04e-05	195	149	6	d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC6 TTC28 GRIN2C CYFIP2 MLXIPL PHLDB2	5.04e-05	195	149	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	COVID-19-Heart-EC_1\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK4 JCAD EPSTI1 PRAG1 PLEKHG1 HECW2	5.04e-05	195	149	6	50a193475db1bb1e05b8590225a553688c372c14
ToppCell	10x5'\|World / Manually curated celltypes from each tissue	CR2 CYFIP2 MAPK8IP3 DNAAF2 PLEKHG1 NFATC2	5.04e-05	195	149	6	de28b998793271c4f69ce9e183c3e62d809e9cc8
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC6 TTC28 GRIN2C CYFIP2 MLXIPL PHLDB2	5.04e-05	195	149	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LYPD6 RIPOR2 ADARB2-AS1 XKR4 NMU NHS	5.18e-05	196	149	6	7af6c5147ac859353504d19727dbe24f63a29dd4
ToppCell	B_cells-Naive_B_cells_\|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	USP36 RIPOR2 PDE7A FAM53C CYFIP2 PLEKHG1	5.33e-05	197	149	6	fd5fdc5289d681d59ff22d72e4de6e74c6c7aac6
ToppCell	T_cells-CCR7+_T_cells\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	USP36 PAG1 RIPOR2 CYFIP2 IVNS1ABP TBC1D4	5.33e-05	197	149	6	904430779c42b51d3eec62cf0cdd501b17058d8b
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FSTL3 CTIF SCN9A NHS CAMSAP2 TCFL5	5.64e-05	199	149	6	a13f4b8a039304e685464cc8879659824cad5a3e
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_alveolar-Dividing_AT2\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TPRN XKR4 NMU MLXIPL SCN9A PLA2G4F	5.80e-05	200	149	6	befc25cbcbac2c02e5fd33d6e78e59979050090c
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	WHRN LYPD6 ATG9B FRMPD1 NHS	1.28e-04	145	149	5	8b13b576fd2e6e33ccb146860a91a53cee0cdd4d
ToppCell	IIH-CD4-antiviral_CD4\|IIH / Condition, Cell_class and T cell subcluster	RIPOR2 EPSTI1 SP110 NOSIP PTGDR2	1.41e-04	148	149	5	ec626a44cea83f2a0e5c27fc8182f96446d297ac
ToppCell	CV-Healthy-3\|Healthy / Virus stimulation, Condition and Cluster	DOCK3 ANKS6 TENT4B TBC1D4 PHLDB2	1.69e-04	154	149	5	26bf81a86700db7e65c2384ffe94ed4253ea4047
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALT2 TDRD5 KRT39 HECW2 NOBOX	1.75e-04	155	149	5	8fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	TNFRSF9 ANKRD6 TBC1D4 HECW2 TCFL5	1.85e-04	157	149	5	6a0aa66964eecbbc232abf1d2e6c8422e4ce69d0
ToppCell	facs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNFRSF9 RIPOR2 EPSTI1 ADGRB2 CYFIP2	2.02e-04	160	149	5	e4516b093003275084fc327d1597394a436754eb
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	MTHFD1L ITGA3 NHS ZFHX3 PTGDR2	2.02e-04	160	149	5	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	facs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNFRSF9 RIPOR2 EPSTI1 ADGRB2 CYFIP2	2.02e-04	160	149	5	0a507e3d59d7f744d0201a531ea84fa97a68aedb
ToppCell	PND03-Immune-Immune_Myeloid-DC-cDC1\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZNF689 HEPACAM2 ANKRD6 CYFIP2 NFATC2	2.08e-04	161	149	5	0e2b54a63781397f6b99eb0e201fbb820cbd7cc6
ToppCell	facs-Lung-nan-3m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSSK6 TNFRSF9 RIPOR2 PDE7A EPSTI1	2.08e-04	161	149	5	ae1cee34361dde9964581cca99a29578c3b3bd99
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TNFRSF9 ANKRD6 TBC1D4 HECW2 TCFL5	2.08e-04	161	149	5	22fea192cd5f6d3544533d8b10e1d74dfedf0f05
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-Tregs\|Liver / Manually curated celltypes from each tissue	TNFRSF9 FRMPD1 ITGA3 TTBK1 TBC1D4	2.08e-04	161	149	5	e0fd0c5f72d6a2900827e7bc2608ce3b8df5686b
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK3 TNFRSF9 CTTNBP2 ADGRB2 DLK1	2.08e-04	161	149	5	334f540dff3508d451e5e85e8e4e8f3b8d6b74e7
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	MTHFD1L ITGA3 NHS ZFHX3 PTGDR2	2.08e-04	161	149	5	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK3 TNFRSF9 CTTNBP2 ADGRB2 DLK1	2.08e-04	161	149	5	81d44438e4be4e68a59247e62f02026301a8a0c5
ToppCell	facs-Lung-nan-3m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSSK6 TNFRSF9 RIPOR2 PDE7A EPSTI1	2.08e-04	161	149	5	33de3e8b3238fcfc66dfbf89a913a07d464d6c35
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	JCAD SHB CMYA5 SLIT1 ZFHX3	2.14e-04	162	149	5	58da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	JCAD SHB CMYA5 SLIT1 ZFHX3	2.14e-04	162	149	5	4d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK3 KRT81 KRT83 NCR2 ARHGAP20	2.20e-04	163	149	5	00e791358a7eb6c3e95f87afe22153845012e4a1
ToppCell	T_cells-TFH-like_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	WHRN VSIG10 TBC1D4 NHS FAM53B	2.27e-04	164	149	5	b10cf59f4cc37ca6cd0ecf71d7de278cc2bdd8b5
ToppCell	Endothelial-B-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	PKHD1L1 PLEKHG1 HOXD3 HECW2 PEAR1	2.33e-04	165	149	5	b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCell	Influenza_Severe-cDC\|Influenza_Severe / Disease group and Cell class	CTTNBP2 MTHFD1L CD1B SCN9A PTGDR2	2.40e-04	166	149	5	b40bdf0f7f381e25be61188e9f6c294d25a8b824
ToppCell	NS-control-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DOCK4 ZBTB47 HEPACAM2 TBC1D4 SCN9A	2.40e-04	166	149	5	6d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIPOR2 UBAP2 PDE7A LNPEP PCSK4	2.47e-04	167	149	5	484de3ca4a905067c18d06995601479eef8fc15e
ToppCell	droplet-Lung-LUNG-30m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIN2C RNF43 TBC1D4 PLA2G4F PTGDR2	2.54e-04	168	149	5	0e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCell	Control-B_cells-Activated_B_cells\|Control / group, cell type (main and fine annotations)	RIPOR2 PDE7A SP110 CYFIP2 PLEKHG1	2.54e-04	168	149	5	a7159a35fe37f8c241cf8d391debe271e0698105
ToppCell	facs-Liver-Non-hepatocytes-24m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF9 PDE7A EPSTI1 CMYA5 RNF43	2.54e-04	168	149	5	1254c66f0cd53ef3b913933c0b0648d091da07e9
ToppCell	356C-Myeloid-Dendritic-cDC_activated\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	TNFRSF9 ITGA3 PLEKHG1 TBC1D4 TRAFD1	2.68e-04	170	149	5	513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCell	control-Myeloid-Eosinophils\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PAG1 KRT81 SHB LRP5L PTGDR2	2.75e-04	171	149	5	82f736c33ed96c0865618e8f8eb82a5487126bdc
ToppCell	COVID-19-kidney-Bcells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RIPOR2 CR2 SP110 PRAG1 PLEKHG1	2.75e-04	171	149	5	8e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-mature_NK_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPOR2 EPSTI1 SP110 MLXIPL FAM53B	2.75e-04	171	149	5	f12c2e48637b96557afbc2006a3a23ba21b7951e
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-Natural_Killer_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPOR2 EPSTI1 SP110 MLXIPL FAM53B	2.75e-04	171	149	5	12c98dea7370377695c5d22309f78ba03e282a0e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR2 ITGA3 XKR4 PRAG1 NHS	2.83e-04	172	149	5	0c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR2 ITGA3 XKR4 PRAG1 NHS	2.83e-04	172	149	5	eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 RIPOR2 PKHD1L1 PLEKHG1 HECW2	2.90e-04	173	149	5	f193c63cc536d891c9d23043765e320252bb6e65
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	PKHD1L1 PLEKHG1 HOXD3 HECW2 PEAR1	2.90e-04	173	149	5	dba09ba9748871e38a16449d500ae4d7b405c42f
Drug	Amodiaquin dihydrochloride dihydrate [6398-98-7]; Down 200; 8.6uM; PC3; HT_HG-U133A	FSTL3 LRFN3 ARHGAP35 SVEP1 CYFIP2 PHLDB1 SCN9A ZFHX3 LRP5L ULK2	4.93e-07	197	143	10	5747_DN
Drug	Levopropoxyphene napsylate [5714-90-9]; Down 200; 7.4uM; MCF7; HT_HG-U133A	WHRN GPR27 CTIF NEK9 MAPK8IP3 RUSC2 PHLDB1 NF1 BBC3 ULK2	5.41e-07	199	143	10	3543_DN
Drug	Econazole nitrate [24169-02-6]; Down 200; 9uM; MCF7; HT_HG-U133A	LRFN3 ARMC9 MAPK8IP3 PHLDB1 NF1 SUGP2 PXN FAM53B TP53BP1	3.61e-06	192	143	9	7427_DN
Drug	5162773; Down 200; 7uM; MCF7; HT_HG-U133A_EA	USP36 HDAC6 CYFIP2 GPR107 BMP1 MAP1S SUGP2 MAP4K5 BBC3	4.27e-06	196	143	9	892_DN
Drug	Prenylamine lactate [69-43-2]; Down 200; 9.6uM; MCF7; HT_HG-U133A	HDAC6 RNF43 MAPK8IP3 TBC1D4 NF1 FBXO9 SUGP2 FASTK ULK2	4.27e-06	196	143	9	5489_DN
Drug	Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; MCF7; HT_HG-U133A	TNFRSF9 TTC28 KRT83 FRMPD1 GRIN2C NCOR2 PHLDB1 FAM53B NCR2	4.63e-06	198	143	9	7224_UP
Drug	SAHA; Up 200; 10uM; HL60; HT_HG-U133A	DOCK4 ARMC9 ANKRD6 FAM53C CYFIP2 NOSIP TRAFD1 CAMSAP2	1.53e-05	175	143	8	1161_UP
Drug	DNA-PK Inhibitor III; Down 200; 1uM; MCF7; HT_HG-U133A	USP36 TTC28 SP110 GPR107 RUSC2 BMP1 LNPEP DMBT1	3.45e-05	196	143	8	7513_DN
Drug	Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; PC3; HT_HG-U133A	JCAD ARHGAP35 SVEP1 BMP1 PHLDB1 TRAFD1 LRP5L ULK2	3.45e-05	196	143	8	2101_UP
Drug	GSK-3beta Inhibitor VIII; Up 200; 10uM; MCF7; HT_HG-U133A	WHRN TTC28 LRFN3 RNF43 GPR107 IVNS1ABP BMP1 SUGP2	3.45e-05	196	143	8	7092_UP
Drug	Levopropoxyphene napsylate [5714-90-9]; Down 200; 7.4uM; MCF7; HT_HG-U133A	TTC28 SP110 CYFIP2 MAPK8IP3 RUSC2 FASTK LRP5L MOCS1	3.57e-05	197	143	8	5503_DN
Drug	Enalapril maleate [76095-16-4]; Down 200; 8.2uM; MCF7; HT_HG-U133A	SP110 GPR107 BMP1 PHLDB1 SALL2 TRAFD1 NF1 LRP5L	3.70e-05	198	143	8	7428_DN
Drug	Chenodiol [474-25-9]; Down 200; 10.2uM; PC3; HT_HG-U133A	LRFN3 DLK1 SP110 BMP1 PHLDB1 NF1 LNPEP FAM53B	3.70e-05	198	143	8	7310_DN
Drug	Pinacidil [85371-64-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A	GPR27 SP110 GPR107 MAPK8IP3 PHLDB1 TBC1D4 TRAFD1 PXN	3.70e-05	198	143	8	7437_DN
Drug	Cefuroxime sodium salt [56238-63-2]; Down 200; 9uM; MCF7; HT_HG-U133A	HDAC6 ARHGAP35 SP110 GPR107 BMP1 SUGP2 LNPEP PXN	3.70e-05	198	143	8	6261_DN
Drug	Progesterone [57-83-0]; Up 200; 12.8uM; MCF7; HT_HG-U133A	KRT83 CTIF MLXIP NEK9 SVEP1 BMP1 NCOR2 PTGDR2	3.84e-05	199	143	8	3287_UP
Drug	melicopicine	KRT81 KRT83	3.92e-05	2	143	2	CID000101253
Drug	D04583	ARMC9 BMP1	3.92e-05	2	143	2	CID003037234
Drug	tebuquine	KRT81 KRT83	3.92e-05	2	143	2	CID000071991
Drug	3,5-di-O-galloylquinic acid	KRT81 KRT83	3.92e-05	2	143	2	CID000460896
Drug	sulfonamide-3	KRT81 KRT83	1.17e-04	3	143	2	CID009847197
Drug	Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; PC3; HT_HG-U133A	ADGRB2 CTIF MLXIP ARHGAP35 PXN ZFHX3 MOCS1	2.03e-04	190	143	7	4274_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A	DOCK4 SEC24A ARMC9 ANKRD6 SP110 SVEP1 CAMSAP2	2.16e-04	192	143	7	1284_UP
Drug	Nitrendipine [39562-70-4]; Up 200; 11uM; HL60; HT_HG-U133A	DOCK4 FRMPD1 CTIF ARMC9 BMP1 NCOR2 NCR2	2.16e-04	192	143	7	3087_UP
Drug	WY-14643; Down 200; 100uM; PC3; HG-U133A	WHRN NEK9 CYFIP2 GPR107 MAPK8IP3 PHLDB1 SUGP2	2.16e-04	192	143	7	464_DN
Drug	cis-4,7,10,13,16,19-Docosahexaenoic acid ethyl ester; Up 200; 100uM; MCF7; HT_HG-U133A_EA	FRMPD1 SIK3 SP110 GPR107 MAPK8IP3 NF1 MOCS1	2.23e-04	193	143	7	881_UP
Drug	Proadifen hydrochloride [62-68-0]; Up 200; 10.2uM; MCF7; HT_HG-U133A	USP36 FSTL3 KRT83 MAPK8IP3 BMP1 NCR2 MOCS1	2.23e-04	193	143	7	3446_UP
Drug	Y-27632; Up 200; 3uM; MCF7; HT_HG-U133A_EA	ANKRD6 GPR107 BMP1 NCOR2 PHLDB1 NF1 LRP5L	2.23e-04	193	143	7	948_UP
Drug	5155877; Down 200; 10uM; MCF7; HT_HG-U133A	ARMC9 VSIG10 CYFIP2 NCOR2 TBC1D4 NF1 FASTK	2.23e-04	193	143	7	6574_DN
Drug	Phenazopyridine hydrochloride [136-40-3]; Down 200; 16uM; PC3; HT_HG-U133A	ARMC9 SVEP1 GPR107 IVNS1ABP PHLDB1 MAP1S LNPEP	2.23e-04	193	143	7	5758_DN
Drug	ICI 182,780; Up 200; 1uM; PC3; HT_HG-U133A	ARMC9 ARHGAP35 MAPK8IP3 PHLDB1 NF1 DMBT1 NCR2	2.30e-04	194	143	7	1205_UP
Drug	L(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; PC3; HT_HG-U133A	WHRN CTIF ARHGAP35 RNF43 MAPK8IP3 PHLDB1 DMBT1	2.30e-04	194	143	7	5056_UP
Drug	15d-PGJ2; Down 200; 10uM; PC3; HT_HG-U133A	WHRN ADGRB2 NEK9 RNF43 MAPK8IP3 IVNS1ABP NF1	2.30e-04	194	143	7	4455_DN
Drug	Clofilium tosylate [92953-10-1]; Down 200; 7.8uM; PC3; HT_HG-U133A	GPR27 LRFN3 ADGRB2 ARHGAP35 SVEP1 ZFHX3 MOCS1	2.30e-04	194	143	7	4492_DN
Drug	Lactupicrin	KRT81 KRT83	2.33e-04	4	143	2	CID000174880
Drug	lactucin	KRT81 KRT83	2.33e-04	4	143	2	CID000442266
Drug	2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A	TTC28 KRT83 FRMPD1 MAPK8IP3 TBC1D4 FAM53B MOCS1	2.38e-04	195	143	7	6999_UP
Drug	Anabasine [494-52-0]; Up 200; 24.6uM; MCF7; HT_HG-U133A	RIPOR2 KRT83 BMP1 NCOR2 NF1 NCR2 PTGDR2	2.38e-04	195	143	7	6074_UP
Drug	S(+)-Terguride [37686-84-3]; Up 200; 11.8uM; HL60; HT_HG-U133A	ARMC9 ARHGAP35 GPR107 RUSC2 BMP1 DMBT1 NCR2	2.38e-04	195	143	7	3082_UP
Drug	arachidonyl trifluoromethyl ketone; Up 200; 10uM; MCF7; HG-U133A	ARHGAP35 BMP1 NCOR2 TBC1D4 NF1 FASTK ZFHX3	2.38e-04	195	143	7	327_UP
Drug	Flecainide acetate [54143-56-5]; Up 200; 8.4uM; PC3; HT_HG-U133A	HDAC6 CTIF NEK9 RNF43 NF1 PXN BBC3	2.38e-04	195	143	7	4318_UP
Drug	Apramycin [37321-09-8]; Down 200; 7.4uM; PC3; HT_HG-U133A	WHRN JCAD FSTL3 MAPK8IP3 FAM53B ZFHX3 ULK2	2.38e-04	195	143	7	6614_DN
Drug	Telenzepine dihydrochloride [147416-96-4]; Down 200; 9uM; MCF7; HT_HG-U133A	B4GALT2 LRFN3 ARHGAP35 MAPK8IP3 BMP1 PHLDB1 FASTK	2.45e-04	196	143	7	7419_DN
Drug	(-)-Cinchonidine [485-71-2]; Down 200; 13.6uM; PC3; HT_HG-U133A	WHRN HDAC6 MAPK8IP3 RUSC2 NF1 FAM53B CAMSAP2	2.45e-04	196	143	7	5833_DN
Drug	Gossypol [303-45-7]; Down 200; 7.8uM; PC3; HT_HG-U133A	WHRN JCAD FAM53C SVEP1 BMP1 SUGP2 NCR2	2.45e-04	196	143	7	4296_DN
Drug	Picotamide monohydrate [80530-63-8]; Up 200; 10.2uM; MCF7; HT_HG-U133A	DOCK3 WHRN JCAD ADGRB2 MLXIP NEK9 NF1	2.45e-04	196	143	7	2233_UP
Drug	Demecarium bromide [56-94-0]; Up 200; 5.6uM; MCF7; HT_HG-U133A	FRMPD1 SHB ARHGAP35 NEK9 MAPK8IP3 NF1 SUGP2	2.45e-04	196	143	7	6269_UP
Drug	Niridazole [61-57-4]; Up 200; 18.6uM; HL60; HT_HG-U133A	WHRN RIPOR2 SHB NEK9 MAPK8IP3 SALL2 NCR2	2.45e-04	196	143	7	2440_UP
Drug	Methotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; MCF7; HT_HG-U133A	TTC28 CTIF MAPK8IP3 RUSC2 NF1 MAP1S MOCS1	2.45e-04	196	143	7	4723_DN
Drug	Flumequine [42835-25-6]; Up 200; 15.4uM; MCF7; HT_HG-U133A	FRMPD1 CTIF GRIN2C NCOR2 NF1 NCR2 PTGDR2	2.53e-04	197	143	7	2276_UP
Drug	Suprofen [40828-46-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A	TNFRSF9 KRT83 NF1 SUGP2 FASTK LRP5L NCR2	2.53e-04	197	143	7	4123_DN
Drug	Memantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A	KRT83 MAPK8IP3 NF1 FBXO9 MAP1S NCR2 MOCS1	2.53e-04	197	143	7	4135_DN
Drug	Cinoxacin [28657-80-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A	FSTL3 TTC28 ANKRD6 PHLDB1 NF1 FBXO9 NCR2	2.53e-04	197	143	7	3463_UP
Drug	Bumetanide [28395-03-1]; Down 200; 11uM; MCF7; HT_HG-U133A	CYFIP2 BMP1 PHLDB1 NF1 FASTK LRP5L BBC3	2.53e-04	197	143	7	7440_DN
Drug	2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A	B4GALT2 SHB ARHGAP35 NF1 FASTK MAP4K5 FAM53B	2.53e-04	197	143	7	6934_DN
Drug	Amoxicillin [26787-78-0]; Up 200; 11uM; MCF7; HT_HG-U133A	TNFRSF9 FRMPD1 RNF43 SVEP1 GPR107 PHLDB1 MOCS1	2.53e-04	197	143	7	2620_UP
Drug	Roxarsone [121-19-7]; Up 200; 15.2uM; PC3; HT_HG-U133A	RIPOR2 FRMPD1 ARHGAP35 MAPK8IP3 PHLDB1 BBC3 PTGDR2	2.53e-04	197	143	7	5051_UP
Drug	artemether	KRT81 KRT83 ARMC9	2.56e-04	20	143	3	CID000068911
Drug	Ornidazole [16773-42-5]; Down 200; 18.2uM; PC3; HT_HG-U133A	FSTL3 ARMC9 GPR107 RUSC2 NF1 FAM53B ULK2	2.61e-04	198	143	7	5064_DN
Drug	vinblastine sulfate; Down 200; 0.1uM; MCF7; HT_HG-U133A	TTC28 LRFN3 RUSC2 BMP1 LNPEP DMBT1 MOCS1	2.61e-04	198	143	7	7517_DN
Drug	(+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; HL60; HT_HG-U133A	FRMPD1 SHB ARHGAP35 ANKRD6 CYFIP2 BMP1 LRP5L	2.61e-04	198	143	7	3016_DN
Drug	Iobenguane sulfate; Up 200; 10.8uM; MCF7; HT_HG-U133A	DOCK3 HDAC6 MLXIP NF1 LRP5L BBC3 MOCS1	2.61e-04	198	143	7	2878_UP
Drug	Rilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; PC3; HT_HG-U133A	CTIF MAPK8IP3 RUSC2 BMP1 FAM53B ZFHX3 MOCS1	2.61e-04	198	143	7	5107_UP
Drug	Clemizole hydrochloride [1163-36-6]; Up 200; 11uM; MCF7; HT_HG-U133A	GPR27 FRMPD1 SVEP1 BMP1 PHLDB1 NF1 NCR2	2.61e-04	198	143	7	4695_UP
Drug	Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; MCF7; HT_HG-U133A	HDAC6 SP110 CYFIP2 SUGP2 MAP4K5 LRP5L BBC3	2.61e-04	198	143	7	3413_DN
Drug	Suprofen [40828-46-4]; Down 200; 15.4uM; PC3; HT_HG-U133A	WHRN FSTL3 CTIF MAPK8IP3 PXN ZFHX3 MOCS1	2.61e-04	198	143	7	4005_DN
Drug	Moricizine hydrochloride [31883-05-3]; Down 200; 8.6uM; MCF7; HT_HG-U133A	SP110 NEK9 RUSC2 PHLDB1 TBC1D4 NF1 ULK2	2.61e-04	198	143	7	3520_DN
Drug	11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A	TTC28 SIK3 SP110 RUSC2 BMP1 NF1 MOCS1	2.61e-04	198	143	7	7514_DN
Drug	Nifenazone [2139-47-1]; Down 200; 13uM; MCF7; HT_HG-U133A	GPR27 LRFN3 CYFIP2 PHLDB1 NF1 PXN ZFHX3	2.61e-04	198	143	7	6016_DN
Drug	pioglitazone HCl; Down 200; 10uM; MCF7; HT_HG-U133A	MAPK8IP3 BMP1 NCOR2 NF1 NCR2 MOCS1 PTGDR2	2.61e-04	198	143	7	5972_DN
Drug	Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; MCF7; HT_HG-U133A	KRT83 PHLDB1 NF1 MAP1S FASTK FAM53B CAMSAP2	2.61e-04	198	143	7	7018_UP
Drug	Vitamin K2 [11032-49-8]; Down 200; 9uM; MCF7; HT_HG-U133A	WHRN GPR27 CTIF GPR107 TBC1D4 NF1 FAM53B	2.61e-04	198	143	7	3880_DN
Drug	Ketorolac tromethamine [74103-07-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A	TTC28 ARHGAP35 NF1 FBXO9 FASTK PXN NCR2	2.61e-04	198	143	7	6489_DN
Drug	Niridazole [61-57-4]; Up 200; 18.6uM; PC3; HT_HG-U133A	WHRN GPR27 ANKRD6 PHLDB1 NEUROG1 NF1 MOCS1	2.61e-04	198	143	7	4621_UP
Drug	Pyrazinamide [ 98-96-4]; Down 200; 32.4uM; MCF7; HT_HG-U133A	TTC28 NEK9 TBC1D4 NF1 SUGP2 MAP4K5 LRP5L	2.61e-04	198	143	7	2839_DN
Drug	Clozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A	FSTL3 KRT83 FRMPD1 RNF43 BMP1 FBXO9 MOCS1	2.61e-04	198	143	7	2644_UP
Drug	Tiabendazole [148-79-8]; Down 200; 19.8uM; PC3; HT_HG-U133A	ADGRB2 ARHGAP35 GPR107 NCOR2 MAP4K5 ZFHX3 MOCS1	2.61e-04	198	143	7	4579_DN
Drug	N6,2-O-dibutyryladenosine 3,5-cyclic monophosphate sodium salt; Up 200; 2uM; MCF7; HT_HG-U133A_EA	B4GALT2 ADGRB2 ARHGAP35 SP110 NF1 SUGP2 LNPEP	2.61e-04	198	143	7	842_UP
Drug	Tropine [120-29-6]; Down 200; 28.4uM; MCF7; HT_HG-U133A	GPR107 BMP1 TBC1D4 NF1 SUGP2 MAP4K5 ZFHX3	2.61e-04	198	143	7	6264_DN
Drug	Pinacidil [85371-64-8]; Up 200; 16.4uM; HL60; HT_HG-U133A	TNFRSF9 FSTL3 SHB CYFIP2 MAPK8IP3 NCOR2 ZFHX3	2.69e-04	199	143	7	2406_UP
Drug	Tiletamine hydrochloride; Down 200; 15.4uM; PC3; HT_HG-U133A	DLK1 ARHGAP35 SP110 NCOR2 TBC1D4 NF1 FAM53B	2.69e-04	199	143	7	7311_DN
Drug	Ciprofibrate [52214-84-3]; Down 200; 13.8uM; PC3; HT_HG-U133A	SVEP1 MAPK8IP3 PHLDB1 NF1 SCN9A ZFHX3 MOCS1	2.69e-04	199	143	7	5740_DN
Drug	Oxolinic acid [14698-29-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A	HDAC6 FRMPD1 GRIN2C MAPK8IP3 RUSC2 NCOR2 DMBT1	2.69e-04	199	143	7	2266_UP
Drug	Ethoxyquin [91-53-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A	LRFN3 ARHGAP35 SVEP1 RUSC2 FBXO9 ULK2 PTGDR2	2.69e-04	199	143	7	3421_UP
Drug	Quinic acid [86-68-0]; Up 200; 19.6uM; HL60; HT_HG-U133A	B4GALT2 ARMC9 NEK9 TBC1D4 FAM53B ZFHX3 CAMSAP2	2.69e-04	199	143	7	2978_UP
Drug	(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Down 200; 12.2uM; MCF7; HT_HG-U133A	ANKRD6 NEK9 RUSC2 PHLDB1 BBC3 ULK2 MOCS1	2.69e-04	199	143	7	3531_DN
Drug	Oxethazaine [126-27-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A	HDAC6 LRFN3 SP110 BMP1 PHLDB1 SUGP2 PXN	2.69e-04	199	143	7	1484_DN
Drug	Kanamycin A sulfate [25389-94-0]; Down 200; 6.8uM; PC3; HT_HG-U133A	LRFN3 FRMPD1 ADGRB2 CYFIP2 RUSC2 BMP1 MOCS1	2.77e-04	200	143	7	4625_DN
Drug	4-chloroaniline	ANKRD42 ACD SHB HOXD3 SCN9A POLD3 BBC3	2.95e-04	202	143	7	CID000007812
Drug	tebufenozide	CHIA NCOR2 FOXL2	2.97e-04	21	143	3	CID000091773
Drug	TLD-100	DOCK3 ARMC9 BMP1	2.97e-04	21	143	3	CID000224478
Disease	cholesteryl esters to total lipids in large HDL percentage	SIK3 NCOR2 MLXIPL MAP4K5 TP53BP1	9.12e-06	59	140	5	EFO_0022248
Disease	triglycerides to total lipids in large HDL percentage	SIK3 NCOR2 MLXIPL MAP4K5 TP53BP1	9.91e-06	60	140	5	EFO_0022330
Disease	level of Triacylglycerol (51:3) in blood serum	SIK3 MLXIPL MAP4K5	1.22e-05	10	140	3	OBA_2045163
Disease	level of Diacylglycerol (18:1_18:1) in blood serum	SIK3 MLXIPL MAP4K5	1.68e-05	11	140	3	OBA_2045170
Disease	level of Diacylglycerol (18:1_18:2) in blood serum	SIK3 MLXIPL MAP4K5	2.23e-05	12	140	3	OBA_2045171
Disease	triacylglycerol 52:3 measurement	SIK3 MLXIPL MAP4K5	4.56e-05	15	140	3	EFO_0010415
Disease	level of Triacylglycerol (53:3) in blood serum	SIK3 MLXIPL MAP4K5	4.56e-05	15	140	3	OBA_2045165
Disease	triglycerides in large LDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	5.19e-05	43	140	4	EFO_0022319
Disease	free cholesterol to total lipids in IDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	5.19e-05	43	140	4	EFO_0022278
Disease	free cholesterol to total lipids in very small VLDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	5.19e-05	43	140	4	EFO_0022290
Disease	saturated fatty acids measurement	SIK3 MLXIPL MAP4K5 TP53BP1	6.22e-05	45	140	4	EFO_0022304
Disease	MONILETHRIX	KRT81 KRT83	6.68e-05	3	140	2	158000
Disease	Beaded hair	KRT81 KRT83	6.68e-05	3	140	2	cv:C0546966
Disease	monilethrix (is_implicated_in)	KRT81 KRT83	6.68e-05	3	140	2	DOID:0050472 (is_implicated_in)
Disease	triglycerides to total lipids in medium LDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	9.44e-05	50	140	4	EFO_0022334
Disease	cholesteryl esters to total lipids in IDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	9.44e-05	50	140	4	EFO_0022247
Disease	triglycerides to total lipids in large LDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	1.02e-04	51	140	4	EFO_0022331
Disease	polyunsaturated fatty acids to monounsaturated fatty acids ratio	SIK3 MLXIPL MAP4K5 TP53BP1	1.02e-04	51	140	4	EFO_0022302
Disease	triglycerides in HDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	1.19e-04	53	140	4	EFO_0022317
Disease	total lipids in medium VLDL	SIK3 MLXIPL MAP4K5 TP53BP1	1.28e-04	54	140	4	EFO_0022153
Disease	triglycerides in medium HDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	1.28e-04	54	140	4	EFO_0022321
Disease	Monilethrix	KRT81 KRT83	1.33e-04	4	140	2	C0546966
Disease	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 measurement	SVEP1 PEAR1	1.33e-04	4	140	2	EFO_0803113
Disease	level of Phosphatidylinositol (18:1_20:4) in blood serum	ZFHX3 LRP5L	1.33e-04	4	140	2	OBA_2045161
Disease	triglycerides in medium VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	1.37e-04	55	140	4	EFO_0022155
Disease	triglycerides in very large HDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	1.37e-04	55	140	4	EFO_0022324
Disease	cholesterol to total lipids in large HDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	1.37e-04	55	140	4	EFO_0022234
Disease	triglycerides in large VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	1.47e-04	56	140	4	EFO_0022178
Disease	triglycerides in LDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	1.47e-04	56	140	4	EFO_0022320
Disease	triglycerides in very large VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	1.47e-04	56	140	4	EFO_0022325
Disease	triglycerides to total lipids in medium HDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	1.47e-04	56	140	4	EFO_0022333
Disease	cholesteryl esters to total lipids in medium HDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	1.47e-04	56	140	4	EFO_0022251
Disease	free cholesterol to total lipids in medium VLDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	1.58e-04	57	140	4	EFO_0022284
Disease	triglycerides in IDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	1.69e-04	58	140	4	EFO_0022149
Disease	triglycerides in VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	1.80e-04	59	140	4	EFO_0022326
Disease	triglycerides to total lipids in small LDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	1.80e-04	59	140	4	EFO_0022337
Disease	phospholipids in VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	1.80e-04	59	140	4	EFO_0022301
Disease	protein-glutamine gamma-glutamyltransferase e measurement	CYFIP2 MLXIPL MAP4K5 PXN	1.93e-04	60	140	4	EFO_0020690
Disease	cholesterol in chylomicrons and extremely large VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	1.93e-04	60	140	4	EFO_0021898
Disease	total lipids in VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	1.93e-04	60	140	4	EFO_0022314
Disease	cholesterol to total lipids in IDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	1.93e-04	60	140	4	EFO_0022233
Disease	cholesterol to total lipids in medium HDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	1.93e-04	60	140	4	EFO_0022237
Disease	level of Phosphatidylethanolamine (16:0_18:2) in blood serum	SIK3 MAP4K5 RNF111	1.97e-04	24	140	3	OBA_2045136
Disease	triglycerides in small VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	2.05e-04	61	140	4	EFO_0022145
Disease	free cholesterol in very large VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	2.05e-04	61	140	4	EFO_0022274
Disease	free cholesterol in VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	2.05e-04	61	140	4	EFO_0022276
Disease	triglycerides in small HDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	2.19e-04	62	140	4	EFO_0022158
Disease	phospholipids in large VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	2.19e-04	62	140	4	EFO_0022169
Disease	triglycerides in medium LDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	2.19e-04	62	140	4	EFO_0022322
Disease	triglycerides to total lipids in very large HDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	2.19e-04	62	140	4	EFO_0022339
Disease	total lipids in very large VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	2.19e-04	62	140	4	EFO_0022313
Disease	phospholipids in very large VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	2.19e-04	62	140	4	EFO_0022299
Disease	cholangiocarcinoma, sclerosing cholangitis	DOCK3 SP110	2.21e-04	5	140	2	EFO_0004268, EFO_0005221
Disease	triglycerides to total lipids in IDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	2.33e-04	63	140	4	EFO_0022329
Disease	triglycerides to total lipids in medium VLDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	2.33e-04	63	140	4	EFO_0022335
Disease	cholesterol to total lipids in medium VLDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	2.33e-04	63	140	4	EFO_0022239
Disease	free cholesterol to total lipids in medium LDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	2.33e-04	63	140	4	EFO_0022283
Disease	phospholipids in chylomicrons and extremely large VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	2.33e-04	63	140	4	EFO_0022292
Disease	very low density lipoprotein cholesterol measurement	SIK3 NCOR2 MLXIPL TRAFD1 MAP4K5 TP53BP1 RNF111	2.53e-04	260	140	7	EFO_0008317
Disease	triglycerides in small LDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	2.63e-04	65	140	4	EFO_0022323
Disease	cholesterol in large VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	2.63e-04	65	140	4	EFO_0021902
Disease	cholesterol in very large VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	2.63e-04	65	140	4	EFO_0022230
Disease	glycoprotein measurement	PRAG1 MLXIPL MAP4K5 ZFHX3 TP53BP1	2.65e-04	119	140	5	EFO_0004555
Disease	total lipids in small VLDL	SIK3 MLXIPL MAP4K5 TP53BP1	2.95e-04	67	140	4	EFO_0022148
Disease	total lipids in large VLDL	SIK3 MLXIPL MAP4K5 TP53BP1	2.95e-04	67	140	4	EFO_0022175
Disease	cholesterol to total lipids in very small VLDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	2.95e-04	67	140	4	EFO_0022245
Disease	triglycerides in very small VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	3.12e-04	68	140	4	EFO_0022144
Disease	triglycerides to phosphoglycerides ratio	SIK3 MLXIPL MAP4K5 TP53BP1	3.12e-04	68	140	4	EFO_0022327
Disease	free cholesterol in large VLDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	3.12e-04	68	140	4	EFO_0022265
Disease	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer	SIK3 MLXIPL MAP4K5 ZFHX3	3.30e-04	69	140	4	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Disease	triglycerides to total lipids in very small VLDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	3.30e-04	69	140	4	EFO_0022341
Disease	hematocrit	JCAD UBAP2 CTIF RNF43 NOSIP PLEKHG1 PWWP2A NCOR2 TBC1D4 MAP4K5 ARID2 POLD3 DMBT1 TP53BP1	3.35e-04	1011	140	14	EFO_0004348
Disease	cholesteryl esters to total lipids in very small VLDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	3.69e-04	71	140	4	EFO_0022259
Disease	triglycerides to total lipids in small HDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	3.89e-04	72	140	4	EFO_0022336
Disease	free cholesterol to total lipids in large LDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	4.32e-04	74	140	4	EFO_0022280
Disease	very low density lipoprotein particle size measurement	SIK3 NOSIP MLXIPL MAP4K5 TP53BP1	4.42e-04	133	140	5	EFO_0008594
Disease	free cholesterol to total lipids in small VLDL percentage	SIK3 MLXIPL MAP4K5 TP53BP1	4.54e-04	75	140	4	EFO_0022287
Disease	1-palmitoyl-GPE (16:0) measurement	MAP4K5 TP53BP1	4.62e-04	7	140	2	EFO_0800245
Disease	polycystic liver disease (implicated_via_orthology)	HDAC6 LRP5L	4.62e-04	7	140	2	DOID:0050770 (implicated_via_orthology)
Disease	Premature ovarian failure	FOXL2 NOBOX	4.62e-04	7	140	2	cv:C0085215
Disease	monounsaturated fatty acids; 16:1, 18:1 measurement	SIK3 MLXIPL MAP4K5 TP53BP1	5.27e-04	78	140	4	EFO_0022187
Disease	cholesterol in large HDL measurement	SIK3 MLXIPL MAP4K5 TP53BP1	5.81e-04	80	140	4	EFO_0021900
Disease	free cholesterol measurement, very low density lipoprotein cholesterol measurement	SIK3 NCOR2 MLXIPL MAP4K5 TP53BP1 RNF111	5.82e-04	215	140	6	EFO_0008317, EFO_0008591
Disease	triacylglycerol 52:4 measurement	SIK3 MLXIPL MAP4K5	6.66e-04	36	140	3	EFO_0010416
Disease	cholesteryl esters to total lipids in medium LDL percentage	SIK3 MLXIPL MAP4K5	7.22e-04	37	140	3	EFO_0022252
Disease	very low density lipoprotein cholesterol measurement, phospholipid measurement	SIK3 NCOR2 MLXIPL MAP4K5 TP53BP1 RNF111	8.09e-04	229	140	6	EFO_0004639, EFO_0008317
Disease	beta-defensin 1 measurement	MLXIPL MAP4K5	9.81e-04	10	140	2	EFO_0801415
Disease	cholesteryl esters to total lipids in small LDL percentage	SIK3 MLXIPL MAP4K5	1.05e-03	42	140	3	EFO_0022255
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	SIK3 NCOR2 MLXIPL MAP4K5 TP53BP1 RNF111	1.10e-03	243	140	6	EFO_0004612, EFO_0020944
Disease	cholesteryl esters to total lipids in small HDL percentage	SIK3 MLXIPL MAP4K5	1.12e-03	43	140	3	EFO_0022254
Disease	level of Ceramide (d40:1) in blood serum	SIK3 MAP4K5	1.20e-03	11	140	2	OBA_2045185
Disease	follistatin measurement	MAP4K5 TP53BP1	1.20e-03	11	140	2	EFO_0010614
Disease	alcohol use disorder measurement, alcohol consumption measurement	MLXIPL NF1 MAP4K5 ZFHX3	1.20e-03	97	140	4	EFO_0007878, EFO_0009458
Disease	blood urea nitrogen measurement	PAG1 PDE7A MLXIP MLXIPL PHLDB1 MAP4K5 FAM53B ZRANB1	1.47e-03	452	140	8	EFO_0004741
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	SIK3 MLXIPL MAP4K5 TP53BP1	1.49e-03	103	140	4	EFO_0008595, EFO_0020944
Disease	phosphoglycerides measurement	NCOR2 MLXIPL MAP4K5	1.55e-03	48	140	3	EFO_0022291
Disease	level of Phosphatidylcholine (16:0_18:3) in blood serum	MAP4K5 RNF111	1.68e-03	13	140	2	OBA_2045072
Disease	myeloid white cell count	JCAD TTC28 CTIF DLK1 SIK3 KMT2E MLXIPL LNPEP MAP4K5 FAM53B ZFHX3 BBC3	1.74e-03	937	140	12	EFO_0007988
Disease	polyunsaturated fatty acids to total fatty acids percentage	SIK3 MLXIPL MAP4K5	1.74e-03	50	140	3	EFO_0022303
Disease	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	SIK3 MLXIPL MAP4K5	1.84e-03	51	140	3	EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928

Protein segments in the cluster

Peptide	Gene	Start	Entry
ACVSSPPRNSLSTAA	TDRD5	386	Q8NAT2
SGPLRETRPCNNSAT	ADGRB2	346	O60241
NCSRPNATASSSGLP	B4GALT2	66	O60909
QRCQASTTVNPAPGA	EIF2D	526	P41214
SSCSFSRGRAPPQQN	CTIF	71	O43310
GSAQACPCQVPRAAS	BBC3	6	Q96PG8
TTTAPRNCPSFAVGT	GJA10	371	Q969M2
TLPATQASPAGQSSC	ARID2	1216	Q68CP9
QASPAGQSSCTTATP	ARID2	1221	Q68CP9
ALGLQSASCTAPAQP	CHIA	386	Q9BZP6
CAPSTPAATRAQQTG	ADARB2-AS1	56	A8MUL3
ITCATPSGPTDTAQA	CAPN13	226	Q6MZZ7
AVQASNASASPPSGC	HCCS	11	P53701
NASCVPSPEGGSRAQ	CD1B	146	P29016
SRPVTNCASSPCQNG	DLK1	206	P80370
AAVPGNTSTPSCQST	BMP1	86	P13497
QARSSCSPGGRTPAA	MTHFD1L	56	Q6UB35
HRAQQPAASSTCGQP	ANKRD6	631	Q9Y2G4
NSGPSTSSRETANPC	ANKRD42	6	Q8N9B4
FATSVSPCDGQPATT	C17orf113	221	A0A1B0GUU1
PGCSSPAAAVLENQR	RIMBP3B	16	A6NNM3
PGCSSPAAAVLENQR	RIMBP3C	16	A6NJZ7
CPPASVSQRAGITAA	GPR107	471	Q5VW38
APGPASSQCSSAAEI	NOBOX	376	O60393
SNATPCAVLRPSGAV	NOSIP	231	Q9Y314
CQSPRGSPVSSPQNS	HECW2	1161	Q9P2P5
NRPEPSCNGPVSSSS	TENT4B	436	Q8NDF8
PRSCPQGQAASSATT	FASTK	456	Q14296
VPRGECSGPATVNNS	NCOR2	731	Q9Y618
APCQQFRTGLSSPDA	NFATC2	726	Q13469
RGDALPLQCSPTSSQ	C22orf23	56	Q9BZE7
AASQQPPAPSTVCSA	FOXB2	386	Q5VYV0
AACGSPASQLVATPS	MAP1S	596	Q66K74
GAPSTTNAIAPVSCS	MAGEB18	66	Q96M61
NVPRSNCSSRGDTPV	MAPK8IP3	856	Q9UPT6
SCRPRSPAGQVAAAS	NMU	6	P48645
QTQSCVPPTAGARQA	NCR2	151	O95944
DCARLQQAASASGPP	NEUROG1	31	Q92886
EASSPRLNPAVTCAG	NEK9	866	Q8TD19
STGCLSSPNATVQSP	IVNS1ABP	271	Q9Y6Y0
SPSTPCQNCSRITNV	KRT39	11	Q6A163
NVCSNALVGAPSSRP	DNAAF2	91	Q9NVR5
RLVATAASPPAGCQA	ERVFC1-1	86	P60608
SCGPQQASRPGSTAS	ARMC9	791	Q7Z3E5
SASRTSEAGFCNQPP	JCAD	86	Q9P266
SPDRSACQSAVCGPQ	EPSTI1	201	Q96J88
QSPASRAPGPSQSFC	C9orf131	796	Q5VYM1
PSRANVLSSPCDQAG	FAM53B	171	Q14153
AQFPCCQSPRTTQAT	GPR27	351	Q9NS67
PTGPQVTSSACVQRD	PCSK4	586	Q6UW60
SSVRPPGACQANETI	ITGA3	686	P26006
RLAGTLNPSDPNTCS	PEAR1	16	Q5VY43
SSSALFGCPNPRQLS	PDE7A	31	Q13946
APTSAPGLQFACARQ	FOXL2	336	P58012
NSPCQERSRSPAVNG	KMT2E	836	Q8IZD2
ATCASSRPTQPGLAA	LRP5L	231	A4QPB2
RQSPDGACSVPSART	LNPEP	96	Q9UIQ6
GVSSSTNPFRPQKVC	GNG5	51	P63218
PAPVSSVCSQTNGAL	LRFN3	576	Q9BTN0
SVCSQTNGALGPTPT	LRFN3	581	Q9BTN0
GACQTPTVGNRQTPT	PMS2P1	86	A4D2B8
PTSSGTAQPLANAVC	PRR25	91	Q96S07
SACSIQSSAPLRAPA	HOXD3	66	P31249
VPRRAVGPSSTQACQ	CYFIP2	546	Q96F07
ASPSPAQTRIVANCS	PLA2G4F	76	Q68DD2
SCAASPQTGPLNRAL	PTGDR2	376	Q9Y5Y4
PGTVTSSCSPGNNSR	POU2F3	376	Q9UKI9
SSARSCSSGAPVTQP	MOCS1	16	Q9NZB8
SVSNPQDSVGSPCSR	PXN	96	P49023
QVTVTGPSRDCPNSG	MLXIP	671	Q9HAP2
SGPAPRCELSTSAVQ	CR2	336	P20023
LSPACSGTSTPRGNV	DOCK3	1636	Q8IZD9
GSPRVCRNSAPASVS	DOCK4	1606	Q8N1I0
CRNSAPASVSPDGTR	DOCK4	1611	Q8N1I0
PQASGASCLARTSGP	DMRTC2	271	Q8IXT2
SSINPVSASSCRPGA	CTTNBP2	666	Q8WZ74
PGVSSSNLENRPCRA	FBXO9	56	Q9UK97
CPRPQSCVVDQTGSA	FSTL3	176	O95633
CSNPGSSGPDTAQAR	FRMPD1	971	Q5SYB0
VCSREGSTVNSPPGN	CMYA5	106	Q8N3K9
ESSASNTRAPGNSPC	ANKS6	856	Q68DC2
SARGPSTPGVLSNCT	ATG9B	746	Q674R7
ATTSPINQTNGHPRC	LYPD6	141	Q86Y78
PVCSRASSSRCQQPS	KRTAP10-11	206	P60412
SSVPCNSPSAGQVFS	KRTAP24-1	91	Q3LI83
IPSRSVPASDCVSGQ	HEPACAM2	426	A8MVW5
SSPEGSCREVPQAAS	FAM90A20P	231	A6NIJ5
ESPGAPCRSAQASVS	HDAC6	411	Q9UBN7
AGVICSASQSQPTPS	DMBT1	1346	Q9UGM3
RFLQAPSASSQCAPA	FAM53C	171	Q9NYF3
NGFTVSCGTPSPRAA	SCUBE3	441	Q8IX30
APSSSASSGPNQCVI	SALL2	621	Q9Y467
CGPRRSSSASPQEQD	POLRMT	36	O00411
NRSAPPCANSTVGVV	C2CD5	861	Q86YS7
GNTREALSPCPSTVS	CAMSAP2	666	Q08AD1
QASVGPSCVSPNHRQ	CCDC24	221	Q8N4L8
RPVTGSVCSAPCNGN	KRT83	451	P78385
RQSSPSCGPVAETSS	MAP4K5	431	Q9Y4K4
TCPPQTTARDSQGRG	NUTM2A	671	Q8IVF1
TCPPQTTARDSQGRG	NUTM2E	671	B1AL46
LSPVQSAQRCSSSPF	ARHGAP20	1101	Q9P2F6
SLSGCSRTQQPAPLA	RUSC2	721	Q8N2Y8
PQSRCTSTRSAGEAP	PWWP2A	506	Q96N64
GNPSSICSPVSAIGQ	TNRC6C	121	Q9HCJ0
PQAVPQASSAASASC	SHB	41	Q15464
SCNPSRALPSLNTGS	TRAFD1	311	O14545
NENSARSTAGCLPVP	SPATA22	6	Q8NHS9
LSPCSPRVNAEGFSS	NHS	1576	Q6T4R5
PGCSSPAAAVLENQR	RIMBP3	16	Q9UFD9
ASQTNHCPRASSQPT	SEC24A	146	O95486
SPRTQSPGGCSAEAV	HEXIM2	71	Q96MH2
SNSAAPSGRLSNPQC	RNF43	601	Q68DV7
GSRFPASQVPNRSEC	SCN9A	1356	Q15858
RAQECVSQASSPTPP	SIK3	1066	Q9Y2K2
CSGTVFSAPQNRSPP	WHRN	616	Q9P202
TRVTTNPSDSGKCPN	SI	51	P14410
QCAAAVPRAPAESSS	POLD3	136	Q15054
PCAPRVSEPGTSSQQ	SP110	151	Q9HB58
QSNSCGSVLPPSLAA	PHLDB2	931	Q86SQ0
VDCSSPPVSANGQVR	SVEP1	2831	Q4LDE5
LQARNSCPGPLDSSA	MLXIPL	356	Q9NP71
YTSIQGDPQRSPSSC	PAG1	341	Q9NWQ8
EVFNSPRAGSPLCNS	ARHGAP35	966	Q9NRY4
PASAPSEACRRQSSG	RIPOR2	511	Q9Y4F9
ASGVSVLPQNRSSPC	SCRN1	276	Q12765
DPGQRSSSQPSPAIC	ACD	306	Q96AP0
PGTGSSTAVNSCSPQ	UBAP2	336	Q5T6F2
SSPLEPGACNGSRNS	USP4	641	Q13107
PGSPSRQACSSQPAQ	TTBK1	481	Q5TCY1
RPPQVQAPCGANSSS	RNF111	541	Q6ZNA4
NVCGRAPSPTSSAGE	SOGA1	1296	O94964
APALSQASSGTCFPR	SUGP2	936	Q8IX01
TRSLQDPCSNCPAGT	TNFRSF9	21	Q07011
SATAAAASSCPQPGA	XKR4	176	Q5GH76
AGCSGTPPICRQAQT	NF1	671	P21359
CDSGSQAVPSPATRS	TP53BP1	621	Q12888
GSCTSTVPAPAIFNS	PKHD1L1	2636	Q86WI1
SLTGASPCQSPCVQR	PHLDB1	546	Q86UU1
APSCRTNGVAISDPS	PRAG1	596	Q86YV5
TVALAQPAASCTPAA	ZBTB47	121	Q9UFB7
PAGASQPALTSSRVC	TBC1D4	281	O60343
GSSPNSQAVLLPSVC	FP248	156	Q71RG6
SCSPVPADTAQTVGR	ULK2	451	Q8IYT8
PTSDPGDRLQQCSST	TTC28	1806	Q96AY4
APNCSPRSAIGGSSQ	ZNF689	481	Q96CS4
PASATPSQRQCVSAA	TPRN	276	Q4KMQ1
SPSARPSAGQVARNC	TSSK6	251	Q9BXA6
GSQVDFSCNSSSRPP	VSIG10	146	Q8N0Z9
VRRASSAGESNTCPP	PLEKHG1	606	Q9ULL1
SGSPVRVCQFSPDST	WDSUB1	96	Q8N9V3
TNPIETSGARCASPR	SLIT1	456	O75093
SLVTCPAQGSLQSSP	TCFL5	481	Q9UL49
SCSSGNSQRRSPPAT	ZRANB1	206	Q9UGI0
AVVPESSSCAPSANG	USP36	986	Q9P275
AAAANISSSCGAPSP	ZFHX3	781	Q15911
RPVTGSVCSAPCNGN	KRT81	446	Q14533
CFSGVQSLASPPRQA	GRIN2C	866	Q14957