Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentmicrotubule organizing center

CCDC14 STARD9 CFAP20 NR0B1 NINL CCNJ CAMSAP1 FIGN NCKAP5L YES1 TUBGCP5 USH2A CCDC116 WDR62

9.20e-069198014GO:0005815
HumanPhenoOverhanging nasal tip

TGFB3 TCF4 ATN1

3.34e-068213HP:0011833
MousePhenodecreased IgD level

IGHD EBF1 TP53BP1

5.15e-0516653MP:0002491
MousePhenoabnormal IgD level

IGHD EBF1 TP53BP1

6.23e-0517653MP:0020172
DomainVWD

MUC5B TECTA MUC4

3.63e-0516773SM00216
DomainVWF_type-D

MUC5B TECTA MUC4

3.63e-0516773IPR001846
DomainVWFD

MUC5B TECTA MUC4

3.63e-0516773PS51233
DomainVWD

MUC5B TECTA MUC4

3.63e-0516773PF00094
DomainSEA

UMODL1 MUC16 MUC12

9.81e-0522773PF01390
DomainSEA

UMODL1 MUC16 MUC12

1.12e-0423773PS50024
DomainSEA_dom

UMODL1 MUC16 MUC12

1.12e-0423773IPR000082
DomainNIDO_dom

TECTA MUC4

1.66e-045772IPR003886
DomainNIDO

TECTA MUC4

1.66e-045772SM00539
DomainNIDO

TECTA MUC4

1.66e-045772PF06119
Domain-

RBM27 RBM26

1.66e-0457721.20.1390.10
DomainNIDO

TECTA MUC4

1.66e-045772PS51220
DomainPWI

RBM27 RBM26

1.66e-045772PF01480
DomainPWI_dom

RBM27 RBM26

1.66e-045772IPR002483
DomainLaminin_EGF

NTN5 USH2A MEGF10

4.01e-0435773PF00053
DomainEGF_Lam

NTN5 USH2A MEGF10

4.01e-0435773SM00180
DomainLaminin_EGF

NTN5 USH2A MEGF10

5.12e-0438773IPR002049
DomainEGF_1

UMODL1 NTN5 MUC12 USH2A MUC4 MEGF10

6.44e-04255776PS00022
DomainTIL

MUC5B TECTA

1.08e-0312772PF01826
DomainC8

MUC5B TECTA

1.08e-0312772PF08742
DomainPMG

KRTAP13-2 KRTAP13-3

1.27e-0313772PF05287
DomainUnchr_dom_Cys-rich

MUC5B TECTA

1.27e-0313772IPR014853
DomainC8

MUC5B TECTA

1.27e-0313772SM00832
DomainKRTAP_PMG

KRTAP13-2 KRTAP13-3

1.27e-0313772IPR007951
DomainZP_1

UMODL1 TECTA

1.48e-0314772PS00682
DomainTIL_dom

MUC5B TECTA

1.48e-0314772IPR002919
DomainZP_2

UMODL1 TECTA

1.48e-0314772PS51034
DomainZP

UMODL1 TECTA

1.70e-0315772SM00241
DomainEMI_domain

UMODL1 MEGF10

1.94e-0316772IPR011489
DomainZP_dom

UMODL1 TECTA

2.19e-0317772IPR001507
DomainZona_pellucida

UMODL1 TECTA

2.19e-0317772PF00100
DomainEMI

UMODL1 MEGF10

2.19e-0317772PS51041
DomainIg-like_fold

MYBPH KALRN IGHD UMODL1 EBF1 USH2A PTGFRN PALLD GPA33

2.43e-03706779IPR013783
DomainVWC_out

MUC5B TECTA

2.74e-0319772SM00215
DomainWD40

TRAF7 COP1 MAPKBP1 WDR62 DMXL1

4.33e-03259775PF00400
Domainfn3

MYBPH KALRN UMODL1 USH2A

4.52e-03162774PF00041
DomainZnf_RING_CS

TRAF7 SH3RF2 SHPRH COP1

4.62e-03163774IPR017907
DomainEGF_2

UMODL1 NTN5 MUC12 MUC4 MEGF10

4.77e-03265775PS01186
DomainWD40

TRAF7 COP1 MAPKBP1 WDR62 DMXL1

5.00e-03268775SM00320
DomainWD40_repeat

TRAF7 COP1 MAPKBP1 WDR62 DMXL1

5.32e-03272775IPR001680
DomainWD_REPEATS_1

TRAF7 COP1 MAPKBP1 WDR62 DMXL1

5.82e-03278775PS00678
Domain-

MYBPH KALRN UMODL1 EBF1 USH2A PTGFRN PALLD GPA33

5.90e-036637782.60.40.10
DomainWD_REPEATS_2

TRAF7 COP1 MAPKBP1 WDR62 DMXL1

5.91e-03279775PS50082
DomainWD_REPEATS_REGION

TRAF7 COP1 MAPKBP1 WDR62 DMXL1

5.91e-03279775PS50294
DomainEGF_LAM_2

NTN5 USH2A

6.77e-0330772PS50027
DomainEGF_LAM_1

NTN5 USH2A

6.77e-0330772PS01248
DomainFN3

MYBPH KALRN UMODL1 USH2A

7.19e-03185774SM00060
DomainWD40_repeat_dom

TRAF7 COP1 MAPKBP1 WDR62 DMXL1

7.65e-03297775IPR017986
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC5B MUC12 MUC4

1.75e-0716464M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC5B MUC12 MUC4

2.29e-0717464M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC12 MUC4

8.40e-0723464M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC16 MUC5B MUC12 MUC4

1.41e-0626464M27483
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC4

4.15e-0521463MM15706
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC12 MUC4

4.82e-0562464M546
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC16 MUC5B MUC12 MUC4

6.94e-0568464M27303
PathwayREACTOME_EPHB_MEDIATED_FORWARD_SIGNALING

ARHGEF28 KALRN YES1

2.34e-0437463MM15022
PathwayREACTOME_EPHB_MEDIATED_FORWARD_SIGNALING

ARHGEF28 KALRN YES1

3.41e-0442463M27308
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC5B MUC12 MUC4

4.61e-04111464M27416
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC4

9.77e-0460463MM15636
PathwayPID_ERB_GENOMIC_PATHWAY

NCOA2 NR0B1

1.06e-0315462M119
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC16 MUC5B MUC12 MUC4

1.10e-03140464M27484
PathwayPID_ERA_GENOMIC_PATHWAY

NCOA2 NR0B1 GREB1

1.18e-0364463M200
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC16 MUC5B MUC12 MUC4

1.19e-03143464M27275
PathwayREACTOME_EPH_EPHRIN_SIGNALING

ARHGEF28 KALRN YES1

1.23e-0365463MM14911
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC16 MUC5B MUC12 MUC4

8.15e-081881418834073
Pubmed

A global genomic transcriptional code associated with CNS-expressed genes.

NCOA2 TCF4 ANGEL2 SHPRH EBF1 FIGN USH2A PMFBP1

8.06e-0731881816919269
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

TRAF7 TCF4 RBM27 CFAP20 ANGEL2 MUC16 EBF1 TP53BP1

4.10e-0639681826687479
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

CCDC14 RBM27 ZNF217 CAMSAP1 NCKAP5L PALLD

4.72e-0618481632908313
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

NCOA2 TCF4 NACC2 CFAP20 CHAF1A RBM26 COP1 CAMSAP1 FOXJ3 NKRF TP53BP1

4.81e-06857811125609649
Pubmed

Human transcription factor protein interaction networks.

NCOA2 TCF4 ATN1 RBM27 ATXN7 GLI2 PHF12 COP1 ZNF217 GMEB2 FIGN NKRF TP53BP1 FILIP1L

5.08e-061429811435140242
Pubmed

A family of RS domain proteins with novel subcellular localization and trafficking.

RBM27 RBM26

5.36e-06281215741184
Pubmed

Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.

MUC16 MUC4

5.36e-06281223544943
Pubmed

Expression of mucins in mucoid otitis media.

MUC5B MUC4

5.36e-06281214690056
Pubmed

Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.

MUC16 MUC4

1.60e-05381223053434
Pubmed

DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.

MUC16 MUC5B

1.60e-05381227230679
Pubmed

Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.

MUC16 MUC4

1.60e-05381230236127
Pubmed

New candidate biomarkers in the female genital tract to evaluate microbicide toxicity.

PGLYRP1 MUC5B

1.60e-05381225333937
Pubmed

Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.

MUC16 MUC4

1.60e-05381217592322
Pubmed

Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.

MUC16 MUC12

1.60e-05381226770020
Pubmed

The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay.

RBM27 RBM26

1.60e-05381231950173
Pubmed

Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.

MUC16 MUC4

1.60e-05381235879412
Pubmed

Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis.

MAPKBP1 WDR62

1.60e-05381228089251
Pubmed

Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).

MUC16 MUC4

1.60e-05381227483328
Pubmed

MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.

MUC16 MUC4

1.60e-05381224204560
Pubmed

Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.

MUC16 MUC4

1.60e-05381224939955
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

NCOA2 KALRN ATXN7 STARD9 BSN NKRF

1.81e-0523381637704626
Pubmed

The Repeat Expansion Diseases: The dark side of DNA repair.

TCF4 ATN1 ATXN7

2.08e-052381326002199
Pubmed

Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts.

TCF4 LGR5

3.20e-05481225620640
Pubmed

Identification and analysis of a novel dimerization domain shared by various members of c-Jun N-terminal kinase (JNK) scaffold proteins.

MAPKBP1 WDR62

3.20e-05481223341463
Pubmed

Lhx2 differentially regulates Sox9, Tcf4 and Lgr5 in hair follicle stem cells to promote epidermal regeneration after injury.

TCF4 LGR5

3.20e-05481222028024
Pubmed

TRPV4 activation in human corneal epithelial cells promotes membrane mucin production.

MUC16 MUC4

3.20e-05481239024979
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RBM27 PHF12 NINL IPO13 ICE1 GMEB2 BSN FOXJ3

3.30e-0552981814621295
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NCOA2 ATN1 RBM27 PHF12 RBM26 ZNF217

3.96e-0526881633640491
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

ATN1 PHF12 RBM26 NINL IPO13 MAPKBP1 MEGF10 ERVFRD-1

4.93e-0556081821653829
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC5B MUC4

5.33e-05581211062147
Pubmed

Peptidoglycan recognition protein Pglyrp2 protects mice from psoriasis-like skin inflammation by promoting regulatory T cells and limiting Th17 responses.

PGLYRP1 PHF12

5.33e-05581222048773
Pubmed

Molecular analysis of CAG repeats at five different spinocerebellar ataxia loci: correlation and alternative explanations for disease pathogenesis.

ATN1 ATXN7

5.33e-05581218182848
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

ELOA ARHGEF28 CFAP20 PHF12 PGAP2 CHAF1A NR0B1 RBM26 COP1 ZNF217 MUC12 TUBGCP5

5.63e-051327811232694731
Pubmed

GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis.

TCF4 GLI2 LGR5

7.55e-053581331167144
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ELOA ATN1 ATXN7 PHF12 CHAF1A RIPOR1 ZNF217 TP53BP1 WDR62

7.99e-0577481915302935
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC16 MUC5B

7.99e-05681219110483
Pubmed

UHRF2 promotes intestinal tumorigenesis through stabilization of TCF4 mediated Wnt/β-catenin signaling.

TCF4 LGR5

7.99e-05681232372448
Pubmed

Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3.

TGFB3 TCF4

7.99e-05681218799618
Pubmed

Inflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasia.

TGFB3 GLI2

1.12e-04781223110168
Pubmed

Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons.

TGFB3 GLI2 EBF1

1.13e-044081327657450
Pubmed

TWIST1 Homodimers and Heterodimers Orchestrate Lineage-Specific Differentiation.

TCF4 EBF1

1.49e-04881232179550
Pubmed

The transcription factor Gli3 promotes B cell development in fetal liver through repression of Shh.

GLI2 EBF1

1.49e-04881228533268
Pubmed

Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity.

TNFRSF10C LGR5

1.49e-04881226609054
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

NHSL1 KALRN BSN CAMSAP1 NCKAP5L

1.61e-0421881533378226
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

RBM27 ATXN7 CFAP20 PHF12 CHAF1A RBM26 ICE1 ZNF217 YES1 FOXJ3 CDC42BPB NKRF

1.75e-041497811231527615
Pubmed

Use of mutant mouse lines to investigate origin of gonadotropin-releasing hormone-1 neurons: lineage independent of the adenohypophysis.

GLI2 EBF1

1.91e-04981220008041
Pubmed

Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.

KALRN SH3RF2 YES1

2.20e-045081319807924
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

NCOA2 ATXN7 SHPRH TNFRSF10C FOXJ3 MUC4

2.34e-0437181615747579
Pubmed

Expression of signaling components in embryonic eyelid epithelium.

TCF4 GLI2

2.38e-041081224498290
Pubmed

Screening for premutation in the FMR1 gene in male patients suspected of spinocerebellar ataxia.

ATN1 ATXN7

2.38e-041081219235102
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TRAF7 NHSL1 KALRN PHF12 NINL RIPOR1 ICE1 MAPKBP1 CAMSAP1 CDC42BPB

2.45e-041105811035748872
Pubmed

KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.

ELOA RBM27 RBM26 NKRF

2.48e-0413081435545047
Pubmed

The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development.

MAPKBP1 WDR62

2.91e-041181231816041
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ELOA RBM27 RBM26 ICE1 CAMSAP1 PALLD NKRF TP53BP1 WDR62

3.24e-0493481933916271
Pubmed

Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair.

BSN TP53BP1

3.48e-041281228700933
Pubmed

Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication.

CCDC14 WDR62

4.11e-041381226297806
Pubmed

Bmx is a downstream Rap1 effector in VEGF-induced endothelial cell activation.

ELOA TNFRSF10C

4.11e-041381215207703
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

PHF12 NR0B1 ICE1 ZNF217 CAMSAP1 WDR62

4.42e-0441881634709266
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

NCOA2 TCF4 ATN1 FOXJ3

4.49e-0415281438360978
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

NHSL1 RBM27 STARD9 PTGFRN

4.60e-0415381410718198
Pubmed

Dorsally derived netrin 1 provides an inhibitory cue and elaborates the 'waiting period' for primary sensory axons in the developing spinal cord.

GLI2 EBF1

4.79e-041481216510500
Pubmed

Lymphotoxin-beta regulates periderm differentiation during embryonic skin development.

KRTAP13-3 IPO13

4.79e-041481217673451
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

ATN1 GLI2 BSN CAMSAP1 YES1 FOXJ3

5.12e-0443081635044719
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

CCDC14 ATN1 KALRN ATXN7 NR0B1 MAPKBP1 GMEB2

5.48e-0460881716713569
Pubmed

Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis.

GLI2 EBF1

6.29e-041681215647317
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NCOA2 NACC2 ATXN7 GLI2 SHPRH RIPOR1 GREB1 TECTA FOXJ3 CDC42BPB GPA33

6.60e-041489811128611215
Pubmed

Molecular genetics of hereditary spinocerebellar ataxia: mutation analysis of spinocerebellar ataxia genes and CAG/CTG repeat expansion detection in 225 Italian families.

ATN1 ATXN7

7.12e-041781215148151
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOA2 ATXN7 LZTS1 PHF12 MUC16 BSN FOXJ3

7.28e-0463881731182584
Pubmed

A proteome-scale map of the SARS-CoV-2-human contactome.

ELOA TCF4 KALRN NKRF

7.30e-0417381436217029
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

CFAP20 CHAF1A ANGEL2 MUC4 NKRF TP53BP1

8.05e-0446981627634302
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

CCDC14 PHF12 ARHGAP12 NINL CAMSAP1 NCKAP5L YES1 WDR62

8.42e-0485381828718761
Pubmed

Specific requirement of Gli transcription factors in Hedgehog-mediated intestinal development.

GLI2 LGR5

8.93e-041981223645682
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

ELOA CFAP20 NINL IPO13 RIPOR1 NCKAP5L NKRF TP53BP1 WDR62 PMFBP1

9.81e-041321811027173435
Pubmed

Patterning of ventral telencephalon requires positive function of Gli transcription factors.

GLI2 EBF1

9.91e-042081219632216
Pubmed

The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription.

NCOA2 ELOA

9.91e-042081216957778
Pubmed

Zinc-finger genes Fez and Fez-like function in the establishment of diencephalon subdivisions.

TCF4 EBF1

9.91e-042081216971467
Pubmed

Pinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis.

TCF4 GLI2

9.91e-042081220637749
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

NCOA2 ELOA TCF4 CHAF1A EBF1 XRCC3 GMEB2 NKRF

1.01e-0387781820211142
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

NCOA2 NR0B1

1.09e-032181219596656
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TRAF7 ATN1 ATXN7 PHF12 CHAF1A NCKAP5L TUBGCP5 NKRF WDR62

1.15e-03111681931753913
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

KALRN RBM27 CHAF1A RBM26 PALLD TP53BP1

1.15e-0350381616964243
Pubmed

Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer.

GLI2 PTGFRN

1.31e-032381220932654
Pubmed

Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion.

TGFB3 LGR5

1.31e-032381229981310
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

NCOA2 TCF4 GLI2 NR0B1 ZNF217 EBF1 FOXJ3

1.34e-0370981722988430
Pubmed

E-cadherin is required for intestinal morphogenesis in the mouse.

LGR5 MUC4

1.43e-032481222766025
Pubmed

The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells.

KALRN BSN

1.43e-032481235179492
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

NHSL1 CAMSAP1 PALLD WDR62

1.47e-0320981436779422
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ELOA CHAF1A RBM26 ICE1 CAMSAP1 NCKAP5L WDR62

1.62e-0373381734672954
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ELOA RBM27 RPLP0P6 CHAF1A RBM26 ICE1 NKRF TP53BP1

1.71e-0395481836373674
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

NINL ICE1 PALLD

1.77e-0310281310231032
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NCOA2 RBM27 RBM26 PALLD NKRF TP53BP1

1.80e-0354981638280479
Pubmed

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PALLD TP53BP1

1.81e-032781217525332
Pubmed

A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies.

GLI2 EIF4EBP2

1.81e-032781234242585
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

ELOA ATXN7 RBM26 NKRF

1.83e-0322281437071664
Pubmed

Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ.

GLI2 LGR5

1.95e-032881232674056
Pubmed

Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium.

TCF4 EBF1

1.95e-032881215917450
Pubmed

Fgf10 is required for specification of non-sensory regions of the cochlear epithelium.

TECTA LGR5

2.09e-032981225624266
Pubmed

The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing.

ATN1 RBM26

2.09e-032981217577209
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

ELOA RBM27 CHAF1A NR0B1 RBM26 ZNF217 NKRF TP53BP1

2.14e-0398981836424410
Cytoband14q32.3

XRCC3 CDC42BPB

1.37e-041081214q32.3
Cytoband21q22.1

KRTAP13-2 KRTAP13-3

2.18e-033981221q22.1
CytobandEnsembl 112 genes in cytogenetic band chr15q15

STARD9 MAPKBP1 TP53BP1

2.29e-03147813chr15q15
GeneFamilyCD molecules|Mucins

MUC16 MUC5B MUC12 MUC4

3.24e-0721514648
GeneFamilyWD repeat domain containing

TRAF7 COP1 MAPKBP1 WDR62 DMXL1

8.39e-04262515362
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN LZTS1 GLI2 EBF1 FIGN PALLD FILIP1L

7.59e-0819881779576525a10ed3e3a9d1608077cd16ecda23376f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN LZTS1 STARD9 EBF1 FIGN FILIP1L

3.28e-071508168645b9c7f9511ed6cc9afe04440c2873a3094150
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATN1 KALRN GREB1 PALLD CCDC116 WDR62

5.74e-071658160edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATN1 KALRN GREB1 PALLD CCDC116 WDR62

5.74e-07165816fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN LZTS1 STARD9 GLI2 EBF1 PALLD

1.35e-0619181604c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGFB3 KALRN LZTS1 GLI2 EBF1 FILIP1L

1.35e-061918167b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGFB3 KALRN LZTS1 GLI2 EBF1 FILIP1L

1.35e-06191816cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LZTS1 GLI2 EBF1 FIGN PALLD FILIP1L

1.39e-0619281624e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD FILIP1L

1.43e-06193816c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD FILIP1L

1.43e-061938165b602b1702283184bd3943c2a6f2290b7c37e407
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 GLI2 EBF1 FIGN PALLD FILIP1L

1.48e-0619481690efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 GLI2 EBF1 FIGN PALLD FILIP1L

1.48e-06194816df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN LZTS1 GLI2 EBF1 PALLD FILIP1L

1.57e-06196816b8759e6231e0254797d6c30930407b79440c57bb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD FILIP1L

1.57e-061968163a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD FILIP1L

1.57e-06196816bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD FILIP1L

1.61e-0619781609946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Pro-B|bone_marrow / Manually curated celltypes from each tissue

TCF4 UMODL1 RIPOR1 EBF1 CCDC116

9.74e-06156815b093dbba6662e4fffc8aa577587b77f64ac44b56
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD

1.39e-05168815d19a115365c5415e51c039718d7669de788fcf33
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF4 IGHD UMODL1 RIPOR1 EBF1

1.52e-05171815b6ee3a6bc436df5e9129b8e0bed9fa3078a4ff23
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 LZTS1 STARD9 EBF1 FIGN

1.56e-0517281508a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 LZTS1 STARD9 EBF1 FIGN

1.56e-05172815553701349444eb366df3c11f54bb093434f153c6
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LZTS1 STARD9 EBF1 FIGN FILIP1L

1.79e-05177815452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCellCOVID-19-kidney-REN+Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

TCF4 KALRN LZTS1 STARD9 EBF1

1.89e-05179815342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

TCF4 KALRN STARD9 LGR5 CCDC116

2.05e-051828158b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD

2.05e-0518281544764676ed3f51ba171ce63f669390392fa50a43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD

2.05e-05182815d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

TCF4 KALRN LZTS1 EBF1 FIGN

2.10e-05183815273db6a3b00a93ca852498471187b642b5368185
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2|TCGA-Kidney / Sample_Type by Project: Shred V9

TGFB3 TCF4 LZTS1 GLI2 EBF1

2.27e-051868151e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCellRV-07._Pericyte|RV / Chamber and Cluster_Paper

TGFB3 TCF4 KALRN LZTS1 EBF1

2.27e-05186815c533b264fbe12bc35467486fc7fbde24ba968fe1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 KALRN LZTS1 STARD9 EBF1

2.33e-0518781515d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 KALRN LZTS1 STARD9 EBF1

2.33e-05187815f62074b631fd45ad299c69d71b09267b04d656ee
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 KALRN LZTS1 STARD9 EBF1

2.39e-0518881532f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGFB3 EBF1 FIGN PALLD FILIP1L

2.52e-051908152e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TICRR TCF4 STARD9 CHAF1A WDR62

2.52e-0519081531de1727822e9818652946dfb962daee77ffad68
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGFB3 EBF1 FIGN PALLD FILIP1L

2.52e-051908150028f886c789ba238c031eae5d96acaed4af8c25
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD

2.58e-05191815a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD

2.58e-051918158f6d592edc32fdb901af30501d4360512334e8c2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD

2.65e-05192815bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFB3 SH3RF2 GREB1 LGR5 PALLD

2.65e-051928152cc712186e37fb21a964c032765c36a8b4a852cf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD

2.65e-051928150ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellmetastatic_Brain-Fibroblasts-Pericytes|metastatic_Brain / Location, Cell class and cell subclass

TGFB3 TCF4 LZTS1 EBF1 FILIP1L

2.78e-05194815d1889a3e22d5b88461c81ec3ea0e74bb9bf63e60
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TCF4 IGHD RIPOR1 EBF1 DMXL1

2.78e-05194815ff661419b697aef51a53fdeac8d37d870d65f491
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFB3 GREB1 LGR5 MEGF10 FILIP1L

2.78e-05194815c992e3357f4bf3069f8d697803e5785e49a2ef0a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD

2.78e-05194815e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFB3 GREB1 LGR5 MEGF10 FILIP1L

2.78e-051948157bf6edefd13047e04665dbe34051ef3f481f85a4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 PALLD FILIP1L

2.78e-05194815ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFB3 GREB1 LGR5 MEGF10 FILIP1L

2.78e-0519481519e5beae2c1f8bf42cbe618e89810ce7b01a396c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 PALLD FILIP1L

2.85e-0519581549c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 PALLD FILIP1L

2.85e-05195815cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCell5'-Adult-LargeIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BNIP5 MUC5B MUC12 MUC4 GPA33

2.85e-05195815600174e35574fe7c44dd923adcf43686e7b01e39
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 PALLD FILIP1L

2.85e-05195815dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellEpithelial_cells-Club_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

TCF4 MUC16 MUC5B ZNF217 MUC4

2.85e-05195815b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD

2.85e-05195815edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 PALLD FILIP1L

2.85e-05195815783bfa8110161cbd6def50ce849cae676c39c458
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

TGFB3 GLI2 EBF1 FIGN PALLD

2.85e-051958153d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD

2.92e-051968151522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GLI2 EBF1 FIGN PALLD FILIP1L

2.92e-051968152b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 PALLD FILIP1L

2.92e-05196815fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 PALLD FILIP1L

2.92e-05196815802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD

2.92e-051968151c8294014713684b50885e638668f2ce75f357f0
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TCF4 LZTS1 STARD9 EBF1 FILIP1L

2.99e-05197815f66945f9007d59d4208849c7fd727f8519713fbc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 PALLD FILIP1L

2.99e-0519781585a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD

2.99e-05197815ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 PALLD FILIP1L

2.99e-05197815e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN GLI2 EBF1 FIGN PALLD

2.99e-0519781537f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellParenchymal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TCF4 LZTS1 STARD9 EBF1 FILIP1L

2.99e-0519781541dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GLI2 EBF1 FIGN PALLD FILIP1L

2.99e-0519781580e153790cef37b743e22a7370ff5b3a6abf147d
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGEF28 GLI2 MUC16 MUC5B MUC4

3.07e-05198815af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

TCF4 LZTS1 STARD9 EBF1 FIGN

3.22e-052008150c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TGFB3 PALLD MEGF10 PMFBP1 FILIP1L

3.22e-052008159169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGEF28 SH3RF2 GLI2 MUC16 MUC5B

3.22e-05200815682960e28542a3d6c119047cd0131941932cfdea
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TCF4 LZTS1 STARD9 EBF1 FIGN

3.22e-05200815522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TCF4 LZTS1 STARD9 EBF1 FIGN

3.22e-0520081594f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

BNIP5 MUC16 MUC5B PALLD

4.53e-051088149c7f3e25facfb54ef0be45044999bc36438bbea0
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

BNIP5 MUC16 MUC5B PALLD

4.53e-0510881475d635fc5bb004418db2e1328c24d96b718f10b1
ToppCellsevere_influenza-B_cell|severe_influenza / disease group, cell group and cell class (v2)

TCF4 IGHD ATXN7 EBF1

8.78e-0512881492b250186d6bb08ce4f2f5cc4fb93928f6b92d3a
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TICRR LZTS1 EBF1 WDR62

9.89e-0513281402491930097b75aaeedab9e8200711b0dc610944
ToppCellsevere-Lymphocytic-B_cells_2|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TCF4 IGHD SH3RF2 EBF1

1.11e-0413681456a7b5c2e098b4a49124d1b905257a52eb38b519
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 RIPOR1 EBF1 TNFRSF10C

1.21e-04139814b07929348ec9ad95d7bce33a7deac0938227b19f
ToppCellDividing_Macrophages-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

TICRR MUC12 XRCC3 WDR62

1.70e-04152814e39cfc346b35235546b303e7d73e4d9d7120a5fb
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

TEKT3 NHSL1 NACC2 NTN5

1.93e-041578146a0aa66964eecbbc232abf1d2e6c8422e4ce69d0
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNIP5 MUC16 MUC5B MUC4

2.02e-0415981460b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RBM27 NINL BSN LGR5

2.07e-041608145cd4fbbd2ce671a8377416eff94041a111375dee
ToppCellmetastatic_Brain-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

TGFB3 SH3RF2 MUC16 PALLD

2.12e-04161814e6e294b4ba911c1327664f1a0f93207096c6de03
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TEKT3 NHSL1 NACC2 NTN5

2.12e-0416181422fea192cd5f6d3544533d8b10e1d74dfedf0f05
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 LZTS1 EBF1 FIGN

2.12e-041618141b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GLI2 EBF1 FIGN PALLD

2.22e-04163814bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCell3'_v3-bone_marrow-Lymphocytic_B-ABC_aged-B_memory|bone_marrow / Manually curated celltypes from each tissue

TCF4 IGHD MUC16 EBF1

2.22e-0416381430f5c93c4e170304d701b5231f0d545f404066f7
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF4 IGHD RIPOR1 EBF1

2.22e-041638146bed27d2f67a430a847da5eb47878d14b4949c45
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GLI2 EBF1 FIGN PALLD

2.22e-041638148e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCF4 LZTS1 STARD9 EBF1

2.28e-04164814f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCellClub_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

PGLYRP1 KRTAP13-2 MUC5B MUC4

2.38e-04166814a440aa338aa0c6cd0b5800dfa7e83f8ca16fce1a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LZTS1 GLI2 EBF1 FILIP1L

2.44e-04167814e228b8373ffd4436e6b944e26d0fadf3ac289b21
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LZTS1 GLI2 EBF1 FILIP1L

2.44e-041678147cb1b11e8e24a10115e46ffbb74889e672a7a026
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHAF1A XRCC3 LGR5 NKRF

2.44e-0416781429d271643f3a1718b53db77b7d093ec94225a824
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TICRR TCF4 CHAF1A WDR62

2.44e-04167814bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LZTS1 GLI2 EBF1 FILIP1L

2.44e-04167814bb53a478b5d821d6d82c15bc4ed075b67682457c
ToppCellPosterior_cortex-Endothelial-MURAL|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TGFB3 EBF1 PALLD FILIP1L

2.55e-041698140ae65daf092396b71f790b65c7a2feed90397417
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TGFB3 EBF1 PALLD FILIP1L

2.55e-041698148cd70ce27b1cecb83f8a376230e7ef41b079b124
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CCDC14 NHSL1 PHF12 XRCC3

2.55e-041698142833a8a7094e4d407eb923f2bc59b9b112c6bae4
Diseaseprimary autosomal recessive microcephaly 2 with or without cortical malformations (implicated_via_orthology)

MAPKBP1 WDR62

6.90e-062782DOID:0070293 (implicated_via_orthology)
Diseasecleft lip

ARHGEF28 LZTS1 MUC16 ICE1 EBF1 PTGFRN

1.08e-04284786EFO_0003959
Diseasepremature birth, parental genotype effect measurement

TEKT3 EBF1

2.45e-049782EFO_0003917, EFO_0005939
Diseaseotitis media (is_marker_for)

MUC5B MUC4

3.06e-0410782DOID:10754 (is_marker_for)
Diseasepancreatic ductal carcinoma (is_marker_for)

MUC5B MUC4 PALLD

5.73e-0461783DOID:3587 (is_marker_for)
Diseasecholangiocarcinoma (is_marker_for)

MUC16 MUC5B MUC4

6.59e-0464783DOID:4947 (is_marker_for)
Diseaseunipolar depression, bipolar disorder

TCF4 STARD9 COP1 PMFBP1

7.91e-04156784EFO_0003761, MONDO_0004985
Diseasebacteriemia

SH3RF2 PALLD

9.14e-0417782EFO_0003033
Diseasecomplement factor H-related protein 3 measurement

CCDC14 KALRN ZBTB41 USH2A

1.07e-03169784EFO_0600056
Diseasemean arterial pressure, alcohol drinking

ICE1 EBF1 FIGN

2.26e-0398783EFO_0004329, EFO_0006340
Diseasespontaneous preterm birth

TEKT3 NHSL1 KALRN

2.46e-03101783EFO_0006917
Diseasepancreatic cancer (is_marker_for)

MUC16 MUC4 PALLD

2.46e-03101783DOID:1793 (is_marker_for)
DiseasePigmented Basal Cell Carcinoma

GLI2 XRCC3

2.49e-0328782C1368275
Diseaseunipolar depression, irritable bowel syndrome

TCF4 COP1

2.49e-0328782EFO_0000555, EFO_0003761

Protein segments in the cluster

PeptideGeneStartEntry
SIPESSLYLSHPSCN

UMODL1

1011

Q5DID0
SHSSIIDSTEYSQPP

COP1

321

Q8NHY2
TLCTGHPNNYPSSSS

CCDC116

141

Q8IYX3
SSTSQGSYPCSHPSP

ATN1

576

P54259
TTHTSSYTLQTCPAG

CCNJ

306

Q5T5M9
PHDYCTTPGGTLFST

EIF4EBP2

31

Q13542
TYQGSLSTPPCSETV

CA11

236

O75493
SHYFPDTGIPEVTTC

ANGEL2

456

Q5VTE6
LSNHTGSPRSPSTTY

CHAF1A

766

Q13111
YVSCSKSPNSHDSEP

CAMSAP1

716

Q5T5Y3
SQATPHSSYGLCTST

CCDC14

246

Q49A88
GHLSSSSIYPACSAP

DMXL1

971

Q9Y485
SSGSTYPSTVEIHPD

GMEB2

436

Q9UKD1
DYSHCPSTPATSSTA

MUC5B

1881

Q9HC84
NYTPVSSVPSISSGH

RBM26

231

Q5T8P6
SIGYHTSVSSPTPLV

RBM27

466

Q9P2N5
HSEPSHICYTPGSQS

ARHGEF28

491

Q8N1W1
HICYTPGSQSSSRTG

ARHGEF28

496

Q8N1W1
TNPSYHTLTQCATSP

MEGF10

926

Q96KG7
TYPESTNTPSIHLGA

MUC16

1241

Q8WXI7
EPGEPTTYSSHSTTL

MUC4

541

Q99102
PLPVTYASSASTGHT

MUC4

976

Q99102
ATHCGVPNYLPSVSS

PGAP2

51

Q9UHJ9
PSYSSSTCGSHTVPS

FIGN

161

Q5HY92
SLPTHSTSSSYQLDP

LZTS1

181

Q9Y250
TSPSPCYTTPDSTQL

NCKAP5L

521

Q9HCH0
GKSVTLPCTYHTSTS

GPA33

36

Q99795
GTPVCTSYNLEPHSI

GREB1

646

Q4ZG55
GTNVSTTYITCPADP

CFAP20

51

Q9Y6A4
SGTNHYSTSSCTPPA

TCF4

286

P15884
YSTSSCTPPANGTDS

TCF4

291

P15884
LCSPTETQPTTHGYS

BSN

1581

Q9UPA5
SPACVVSPHATYSTS

NHSL1

401

Q5SYE7
TTPNVYSLCGATPSQ

NHSL1

756

Q5SYE7
YVVVSHTAGSSCNTP

PGLYRP1

56

O75594
ASGSYCPQHVTLPVT

FAM214B

376

Q7L5A3
PPSSTGNCTISGYTV

KALRN

2591

O60229
CYGQVHPQLSPSTIS

GLI2

1246

P10070
CLSDSPSNSSYVETP

TUBGCP5

116

Q96RT8
PVACSCSPTHVTVYS

CDC42BPB

1466

Q9Y5S2
YPSTVTSSHSIGLNC

ATXN7

746

O15265
STSYSQSDSQCGSPP

ARHGAP12

326

Q8IWW6
HPQQGSTLYCVPTST

NR0B1

206

P51843
VHSPTSYLCRPDGTT

PALLD

421

Q8WX93
SQSSLPGTLHCYTGI

ICE1

1086

Q9Y2F5
PLCVSGHRPSISSSY

BNIP5

331

P0C671
ESSDYGHVQSPPSCT

ELOA

196

Q14241
SPHSYTSTAVIPNCG

FILIP1L

926

Q4L180
YTPVTSHPESVSQSL

FOXJ3

251

Q9UPW0
PSPQPATYTCVVSHE

IGHD

346

P01880
NSSSVSPHGYVPSTT

EBF1

461

Q9UH73
VDYSSSCLSSPEHPT

MAPKBP1

1001

O60336
PSNLVYSTDLCSPST

KRTAP13-2

31

Q52LG2
PSNLVYSTDLCSPST

KRTAP13-3

31

Q3SY46
IPGHYPVNETTSSLT

IPO13

346

O94829
PSPAYPVTESCHLSS

LGR5

886

O75473
SCTATHRYPPSSSEE

PMFBP1

286

Q8TBY8
PSDQGHYKCSTPSTD

PTGFRN

111

Q9P2B2
CTESLPTYVTTHPTV

USH2A

2806

O75445
CLQTGYPTVASVPHS

RPLP0P6

226

Q8NHW5
SAPTETGPSVQECYH

LPAL2

16

Q16609
TLATTPGAYSSDPQC

NTN5

331

Q8WTR8
YPSVKSSQCHTGSSP

NKRF

416

O15226
HYPLSCPSGISTQNS

PHF12

491

Q96QT6
EQPCPGSDTSSAHYI

SHPRH

41

Q149N8
CTLTTTYAHPRPTPT

TEKT3

6

Q9BXF9
HTSTPGYSTQLFCSV

MYBPH

391

Q13203
SYCLVVSSPSPSSPH

STARD9

3851

Q9P2P6
YQVPEESGCHTTTTS

NINL

286

Q9Y2I6
PVGVCSSTGNSHSYT

NCOA2

516

Q15596
TSCTVTCPPNSHYES

TECTA

1366

O75443
TYICQACTPTHGPSS

TICRR

1641

Q7Z2Z1
CTSSSTETPGTAYPA

ERVFRD-1

46

P60508
CDQVTYTHSAGRPTP

ZBTB41

31

Q5SVQ8
SPGTPASSHYLSCTI

TNFRSF10C

231

O14798
HCRTPSSSSTLAYSP

TRAF7

56

Q6Q0C0
HSTPIGISNYPESTI

TP53BP1

936

Q12888
TYVSTPSEIHSLSPG

WDR62

781

O43379
LYTCVPAGSPASSST

ZNF217

996

O75362
VPSSCVGQVSTYHPA

SH3RF2

346

Q8TEC5
PGPTHTTTGSTYSAI

RIPOR1

546

Q6ZS17
PHLPPSSCSYTISAE

XRCC3

321

O43542
GPCPYLRSADTTHST

TGFB3

346

P10600
HYGAEPTTVSPCPSS

YES1

31

P07947
LVEEPTSYHSSPGST

MUC12

1961

Q9UKN1
EESTTYHRSPGSTPT

MUC12

2716

Q9UKN1
LVEEPTSYHSSPGST

MUC12

4601

Q9UKN1
EEPTSYHSSPGSIAT

MUC12

4796

Q9UKN1
ASSLPTTDSPTSYHN

NACC2

251

Q96BF6