Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	olfactory receptor activity	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4M2B OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3	1.20e-14	431	95	20	GO:0004984
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR11L1 OR6N2 OR6K2 AVPR1B OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4M2B OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 FSHR OR1D5 OR1E3	1.21e-10	884	95	22	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR11L1 EPHA6 OR6N2 OR6K2 AVPR1B OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4M2B OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 FSHR OR1D5 OR1E3	6.20e-08	1353	95	23	GO:0004888
GeneOntologyMolecularFunction	5-diphosphoinositol pentakisphosphate 1-kinase activity	PPIP5K1 PPIP5K2	2.24e-05	2	95	2	GO:0033857
GeneOntologyMolecularFunction	inositol hexakisphosphate 3-kinase activity	PPIP5K1 PPIP5K2	1.34e-04	4	95	2	GO:0052724
GeneOntologyMolecularFunction	inositol hexakisphosphate 1-kinase activity	PPIP5K1 PPIP5K2	1.34e-04	4	95	2	GO:0052723
GeneOntologyMolecularFunction	inositol hexakisphosphate 5-kinase activity	PPIP5K1 PPIP5K2	2.22e-04	5	95	2	GO:0000832
GeneOntologyMolecularFunction	diphosphoinositol pentakisphosphate kinase activity	PPIP5K1 PPIP5K2	2.22e-04	5	95	2	GO:0000829
GeneOntologyMolecularFunction	inositol hexakisphosphate kinase activity	PPIP5K1 PPIP5K2	2.22e-04	5	95	2	GO:0000828
GeneOntologyMolecularFunction	inositol-1,3,4,5,6-pentakisphosphate kinase activity	PPIP5K1 PPIP5K2	2.22e-04	5	95	2	GO:0000827
GeneOntologyMolecularFunction	3'-5' RNA helicase activity	DHX9 AQR	3.32e-04	6	95	2	GO:0034458
GeneOntologyMolecularFunction	inositol phosphate kinase activity	PPIP5K1 PPIP5K2	1.20e-03	11	95	2	GO:0180030
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4M2B OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3	8.54e-15	432	96	20	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4M2B OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3	3.42e-14	465	96	20	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4M2B OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3	7.52e-14	485	96	20	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4M2B OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3	3.16e-13	524	96	20	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4M2B OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3	6.98e-13	547	96	20	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4M2B OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3	2.18e-12	582	96	20	GO:0050906
GeneOntologyBiologicalProcess	detection of stimulus	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4M2B OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3	1.04e-10	722	96	20	GO:0051606
GeneOntologyBiologicalProcess	sensory perception	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 POU4F2 OR1D4 OR13J1 OR6X1 OR4M2B OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3 PPIP5K2	3.03e-09	1072	96	22	GO:0007600
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	ADCY4 OR11L1 OR6N2 OR6K2 AVPR1B OR4C6 OR10J3 OR4M1 OR1A2 WNK1 OR1D4 OR13J1 OR6X1 OR4M2B OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 FSHR OR1D5 OR1E3	1.59e-08	1395	96	24	GO:0007186
GeneOntologyBiologicalProcess	regulation of cytokinesis	CCP110 OR1A2 PRC1 WNK1 CIT	9.95e-05	99	96	5	GO:0032465
GeneOntologyBiologicalProcess	inositol phosphate metabolic process	AVPR1B INPP5B PPIP5K1 PPIP5K2	1.01e-04	52	96	4	GO:0043647
GeneOntologyBiologicalProcess	Sertoli cell development	NUP210L MAP7 FSHR	1.84e-04	24	96	3	GO:0060009
GeneOntologyBiologicalProcess	cilium movement	STK36 INPP5B OR4M1 NPHP4 CFAP65 OR4M2 HYDIN	2.19e-04	261	96	7	GO:0003341
Domain	Olfact_rcpt	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5	5.16e-13	393	91	18	IPR000725
Domain	7tm_1	OR11L1 OR6N2 OR6K2 AVPR1B OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 FSHR OR1D5	6.79e-11	677	91	20	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR11L1 OR6N2 OR6K2 AVPR1B OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 FSHR OR1D5	8.36e-11	685	91	20	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR11L1 OR6N2 OR6K2 AVPR1B OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 FSHR OR1D5	9.75e-11	691	91	20	PS50262
Domain	GPCR_Rhodpsn	OR11L1 OR6N2 OR6K2 AVPR1B OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 FSHR OR1D5	1.00e-10	692	91	20	IPR000276
Domain	GPCR_Rhodpsn_7TM	OR11L1 OR6N2 OR6K2 AVPR1B OR4C6 OR10J3 OR4M1 OR1A2 OR13J1 OR6X1 OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 FSHR OR1D5	4.36e-10	670	91	19	IPR017452
Domain	LON	LONRF1 LONRF3	3.48e-04	6	91	2	SM00464
Domain	Acid_Pase_AS	PPIP5K1 PPIP5K2	3.48e-04	6	91	2	IPR033379
Domain	LON_N	LONRF1 LONRF3	3.48e-04	6	91	2	PS51787
Domain	LON_substr-bd_dom	LONRF1 LONRF3	3.48e-04	6	91	2	IPR003111
Domain	LON_substr_bdg	LONRF1 LONRF3	3.48e-04	6	91	2	PF02190
Domain	HIS_ACID_PHOSPHAT_2	PPIP5K1 PPIP5K2	4.85e-04	7	91	2	PS00778
Domain	HIS_ACID_PHOSPHAT_1	PPIP5K1 PPIP5K2	4.85e-04	7	91	2	PS00616
Domain	His_Pase_clade-2	PPIP5K1 PPIP5K2	6.45e-04	8	91	2	IPR000560
Domain	His_Phos_2	PPIP5K1 PPIP5K2	6.45e-04	8	91	2	PF00328
Domain	PapD-like	CFAP65 HYDIN	8.27e-04	9	91	2	IPR008962
Domain	-	MYCBP2 KDM4C LONRF1 PJA2 MTMR4 LTN1 SHPRH LONRF3	1.56e-03	449	91	8	3.30.40.10
Domain	Znf_RING/FYVE/PHD	MYCBP2 KDM4C LONRF1 PJA2 MTMR4 LTN1 SHPRH LONRF3	1.79e-03	459	91	8	IPR013083
Domain	zf-RING_2	MYCBP2 PJA2 LTN1	2.08e-03	52	91	3	PF13639
Domain	ZF_RING_1	MYCBP2 LONRF1 PJA2 LTN1 SHPRH LONRF3	2.99e-03	291	91	6	PS00518
Domain	ZF_RING_2	MYCBP2 LONRF1 PJA2 LTN1 SHPRH LONRF3	3.36e-03	298	91	6	PS50089
Domain	RING	MYCBP2 LONRF1 PJA2 LTN1 SHPRH LONRF3	3.77e-03	305	91	6	SM00184
Domain	PUA-like_domain	LONRF1 LONRF3	3.80e-03	19	91	2	IPR015947
Domain	His_PPase_superfam	PPIP5K1 PPIP5K2	4.21e-03	20	91	2	IPR029033
Domain	-	PPIP5K1 PPIP5K2	4.21e-03	20	91	2	3.40.50.1240
Domain	Znf_RING	MYCBP2 LONRF1 PJA2 LTN1 SHPRH LONRF3	5.20e-03	326	91	6	IPR001841
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3	4.81e-13	417	76	19	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5	1.69e-12	389	76	18	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3	7.10e-10	636	76	19	M41834
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR1A2 OR1D2 OR1N2 OR1D5 OR1E3	3.67e-05	70	76	5	MM14984
Pathway	WP_GPCRS_OTHER	OR1A2 OR1D2 OR1F1 OR1D5 OR1E3	1.66e-04	96	76	5	MM15939
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR13J1 OR6X1 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3	1.02e-16	340	98	17	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR13J1 OR6X1 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3	1.02e-16	340	98	17	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR13J1 OR6X1 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3	1.18e-16	343	98	17	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR13J1 OR6X1 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR6C76 OR1D5 OR1E3	1.36e-16	346	98	17	14611657
Pubmed	The human olfactory receptor gene family.	OR11L1 OR6N2 OR6K2 OR4C6 OR10J3 OR4M1 OR1A2 OR1D4 OR13J1 OR6X1 OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR4M2 OR1D5 OR1E3	1.40e-14	541	98	18	14983052
Pubmed	Sequence, structure, and evolution of a complete human olfactory receptor gene cluster.	OR1A2 OR1D4 OR1D2 OR1D5 OR1E3	6.83e-10	16	98	5	10673334
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR10J3 OR1A2 OR1D4 OR13J1 OR4K14 OR6N1 OR1D2 OR1F1 OR1N2 OR1D5	6.89e-10	219	98	10	12213199
Pubmed	Mouse-human orthology relationships in an olfactory receptor gene cluster.	OR1A2 OR1D2 OR1D5 OR1E3	4.11e-09	8	98	4	11170746
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CCP110 MYCBP2 MAP7 WNK1 PJA2 VPS13D MTMR4 NECTIN2 ANKRD11 USP54 PPIP5K2 AQR CCSER1	9.28e-07	861	98	13	36931259
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	STK36 PGAP3 MYCBP2 LONRF1 WNK1 NPHP4 CIT RYR1 TYK2 ORC1 INTS11 ANKRD11 CABIN1 MED13	2.68e-06	1105	98	14	35748872
Pubmed	Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire.	OR1D4 OR1D2 OR1E3	3.52e-06	11	98	3	8004088
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	CCP110 MYCBP2 NACA WNK1 ERLEC1 NBAS MTMR4 TMEM209 USP54 PPIP5K2 KNL1	7.19e-06	733	98	11	34672954
Pubmed	Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases.	PPIP5K1 PPIP5K2	7.86e-06	2	98	2	18981179
Pubmed	Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress.	PPIP5K1 PPIP5K2	7.86e-06	2	98	2	17702752
Pubmed	Novel G protein-coupled receptors: a gene family of putative human olfactory receptor sequences.	OR1D2 OR1D5	7.86e-06	2	98	2	1315913
Pubmed	The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis.	PPIP5K1 PPIP5K2	7.86e-06	2	98	2	28126903
Pubmed	Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.	PPIP5K1 PPIP5K2	7.86e-06	2	98	2	17690096
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	CCP110 MYCBP2 PJA2 A2ML1 USP54	1.02e-05	101	98	5	24613305
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	CCP110 MYCBP2 MAP7 PRC1 WNK1 KARS1 MED25 SHPRH CABIN1 MED13	1.45e-05	645	98	10	25281560
Pubmed	The Asprosin-OLFR734 hormonal signaling axis modulates male fertility.	OR4M1 OR4M2	2.35e-05	3	98	2	31798959
Pubmed	Combinatorial control of ATF4-dependent gene transcription in osteoblasts.	NACA ATF4	2.35e-05	3	98	2	22082360
Pubmed	PPIP5K2 and PCSK1 are Candidate Genetic Contributors to Familial Keratoconus.	PPIP5K1 PPIP5K2	2.35e-05	3	98	2	31852976
Pubmed	Screening of candidate genes at GLC3B and GLC3C loci in Chinese primary congenital glaucoma patients with targeted next generation sequencing.	PGF VPS13D	2.35e-05	3	98	2	36193031
Pubmed	The Asprosin-OLFR734 module regulates appetitive behaviors.	OR4M1 OR4M2	2.35e-05	3	98	2	32337066
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MYCBP2 POLD2 NACA DHX9 ACSL1 ORC1 KARS1 WDR75 A2ML1 RTCA INTS11 LTN1 UTP20 AQR	2.62e-05	1353	98	14	29467282
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	MAP7 PRC1 CIT WDR75 UTP20 KNL1	2.99e-05	210	98	6	16565220
Pubmed	The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.	OR1A2 OR1F1 OR1E3	3.69e-05	23	98	3	10706615
Pubmed	OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin.	OR4M1 OR4M2	4.70e-05	4	98	2	31230984
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CCP110 STK36 KDM4C WNK1 NPHP4 VPS13D LTN1 CCSER1	7.95e-05	493	98	8	15368895
Pubmed	KIF14 and citron kinase act together to promote efficient cytokinesis.	PRC1 CIT	1.17e-04	6	98	2	16431929
Pubmed	Segregation of ipsilateral retinal ganglion cell axons at the optic chiasm requires the Shh receptor Boc.	POU4F2 CDON	1.64e-04	7	98	2	20053908
Pubmed	Novel Roles and Mechanism for Krüppel-like Factor 16 (KLF16) Regulation of Neurite Outgrowth and Ephrin Receptor A5 (EphA5) Expression in Retinal Ganglion Cells.	EPHA6 POU4F2	1.64e-04	7	98	2	27402841
Pubmed	Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling.	MYCBP2 LTN1	1.64e-04	7	98	2	36700049
Pubmed	Shh/Boc signaling is required for sustained generation of ipsilateral projecting ganglion cells in the mouse retina.	POU4F2 CDON	2.18e-04	8	98	2	23678105
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	WNK1 PPIP5K1 CABIN1 PDZD2	2.20e-04	104	98	4	9205841
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	CIT DHX9 NBAS LTN1 UTP20	2.76e-04	202	98	5	33005030
Pubmed	RhoE binds to ROCK I and inhibits downstream signaling.	CIT RHPN2	2.79e-04	9	98	2	12773565
Pubmed	CXCL12 is required for stirrup-shaped stapes formation during mammalian middle ear development.	ACAN CDON	2.79e-04	9	98	2	32319178
Pubmed	Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging.	USP9Y USP54	2.79e-04	9	98	2	37149635
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	MAP7 PRC1 DHX9 ORC1 KARS1 WDR75 NFIC INTS11 TMEM209 ANKRD11 UTP20 CABIN1	2.85e-04	1294	98	12	30804502
Pubmed	Temporal and spatial expression patterns of Hedgehog receptors in the developing inner and middle ear.	ACAN CDON	4.25e-04	11	98	2	29139542
Pubmed	Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.	CCP110 PJA2 PPIP5K2	4.34e-04	52	98	3	9455477
Pubmed	A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction.	MED25 MED13	5.09e-04	12	98	2	23563140
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	STK36 VPS13D MED13 PDZD2	5.13e-04	130	98	4	12421765
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	MYCBP2 LAMA4 WNK1 RYR1 KARS1 LONRF3 MED13	5.27e-04	497	98	7	23414517
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	POLD2 PRC1 DHX9 KARS1 NFIC RTCA CIAO2B MED25 MED13 AQR	5.86e-04	1014	98	10	32416067
Pubmed	A novel docking site on Mediator is critical for activation by VP16 in mammalian cells.	MED25 MED13	6.01e-04	13	98	2	14657022
Pubmed	Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis.	ACAN ATF4	6.01e-04	13	98	2	19767744
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	MYCBP2 POLD2 NACA LTN1 KNL1	6.28e-04	242	98	5	34011540
Pubmed	Structure, function, and activator-induced conformations of the CRSP coactivator.	MED25 MED13	7.00e-04	14	98	2	11834832
Pubmed	Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.	KDM4C FSHR	8.06e-04	15	98	2	20923822
Pubmed	FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation.	MYCBP2 MED13	8.06e-04	15	98	2	31285543
Pubmed	Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3.	MED25 MED13	8.06e-04	15	98	2	18418385
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	MSTO1 DHX9 NBAS KARS1 RTCA INTS11 LTN1 UTP20	8.62e-04	704	98	8	29955894
Pubmed	MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.	POLD2 WNK1 LTN1 CIAO2B	8.77e-04	150	98	4	22678362
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	NACA MAP7 CIT ORC1 WDR75 INTS11 LTN1 MED25 ANKRD11 UTP20 MED13 AQR	1.03e-03	1497	98	12	31527615
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	CCP110 POLD2 LAMA4 NEU3 RYR1 ORC1 PJA2 NFIC SNAPC2 HYDIN MED13	1.05e-03	1293	98	11	15342556
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	MYCBP2 POLD2 QTRT2 MAP7 WNK1 ERLEC1 DHX9 MTMR4 WDR75 NFIC AQR	1.07e-03	1297	98	11	33545068
Pubmed	Streamlined analysis schema for high-throughput identification of endogenous protein complexes.	INTS11 MED25 MED13	1.08e-03	71	98	3	20133760
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	PGAP3 PGF ERLEC1 RYR1 DHX9 KARS1 PRDM13 UTP20	1.14e-03	736	98	8	29676528
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	QTRT2 MAP7 TYK2 PJA2 INTS11 LTN1 CIAO2B USP54 LONRF3 KNL1	1.21e-03	1116	98	10	31753913
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR10J3 OR1A2 OR1E3	1.22e-03	74	98	3	15081110
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CCP110 MYCBP2 QTRT2 MAP7 WNK1 NPHP4 DHX9 ACSL1 KARS1 NECTIN2 PPIP5K2	1.24e-03	1321	98	11	27173435
Pubmed	Msx1-Positive Progenitors in the Retinal Ciliary Margin Give Rise to Both Neural and Non-neural Progenies in Mammals.	POU4F2 CDON	1.30e-03	19	98	2	28011038
Pubmed	An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.	MED25 MED13	1.30e-03	19	98	2	16799563
Pubmed	Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers.	RYR1 TYK2	1.30e-03	19	98	2	8432525
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	CCP110 MYCBP2 MAP7 CIT ERLEC1 LTN1 UTP20 USP54	1.33e-03	754	98	8	33060197
Pubmed	Mitochondrial Raf1 Regulates Glutamine Catabolism.	MYCBP2 CIT MSTO1 USP54 PPIP5K2	1.36e-03	288	98	5	38496616
Pubmed	Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development.	ACAN CDON	1.44e-03	20	98	2	16169709
Pubmed	Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.	INPP5B ACSL1 KARS1 TMEM209 AQR	1.45e-03	292	98	5	12819125
Pubmed	Docking motif-guided mapping of the interactome of protein phosphatase-1.	WNK1 HYDIN KNL1	1.52e-03	80	98	3	19389623
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	MYCBP2 PRC1 DHX9 TMEM209 USP54 AQR	1.57e-03	440	98	6	34244565
Pubmed	Prdm13 regulates subtype specification of retinal amacrine interneurons and modulates visual sensitivity.	POU4F2 PRDM13	1.59e-03	21	98	2	25995483
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	CCP110 MYCBP2 POLD2 PJA2 VPS13D WDR75 USP54	1.66e-03	606	98	7	36538041
Pubmed	Differential Expression of NF2 in Neuroepithelial Compartments Is Necessary for Mammalian Eye Development.	POU4F2 CDON	1.75e-03	22	98	2	29249622
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	MYCBP2 MAP7 PRC1 NECTIN2 LONRF3	1.80e-03	307	98	5	37499664
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	PRC1 NFIC MED25 CABIN1 MED13 KNL1	1.81e-03	453	98	6	29656893
Pubmed	Composite co-activator ARC mediates chromatin-directed transcriptional activation.	MED25 MED13	1.91e-03	23	98	2	10235267
Pubmed	Cartilage-specific overexpression of ERRγ results in Chondrodysplasia and reduced chondrocyte proliferation.	ACAN ATF4	1.91e-03	23	98	2	24349082
Pubmed	Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.	WNK1 WDR75 CIAO2B	2.07e-03	89	98	3	23891004
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	AVPR1B PRC1 DHX9 NFIC MED13	2.19e-03	321	98	5	32098917
Pubmed	Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.	ACAN CDON	2.26e-03	25	98	2	29475039
Pubmed	LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli.	POU4F2 CDON	2.44e-03	26	98	2	26439398
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	AVPR1B NUP210L INPP5B OR10J3 OR6N1 DHX9 ORC1 VPS13D INTS11	2.55e-03	1031	98	9	16710414
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	MYCBP2 DHX9 USP54 AQR	2.61e-03	202	98	4	24639526
Interaction	YWHAG interactions	CCP110 MYCBP2 MAP7 PRC1 WNK1 PJA2 VPS13D MTMR4 RHPN2 NECTIN2 SHPRH ANKRD11 PPIP5K1 USP54 PPIP5K2 AQR CCSER1	1.08e-05	1248	83	17	int:YWHAG
Interaction	OR1D2 interactions	CIT OR1D2	1.68e-05	2	83	2	int:OR1D2
Interaction	HNRNPCL2 interactions	MYCBP2 PRC1 CIT RTCA PPIP5K2 CABIN1 AQR FOXF2	1.72e-05	274	83	8	int:HNRNPCL2
Cytoband	17p13.3	OR1A2 OR1D4 OR1D2 OR1D5 OR1E3	1.36e-06	88	98	5	17p13.3
Cytoband	17q22-q23	MTMR4 MED13	6.73e-05	6	98	2	17q22-q23
Cytoband	1q23.1	OR6N2 OR6K2 OR6N1	1.34e-04	46	98	3	1q23.1
Cytoband	Ensembl 112 genes in cytogenetic band chr15q15	CCNDBP1 PLA2G4E PPIP5K1 KNL1	2.89e-04	147	98	4	chr15q15
Cytoband	Ensembl 112 genes in cytogenetic band chr17p13	OR1A2 OR1D4 OR1D2 OR1D5 OR1E3	9.05e-04	346	98	5	chr17p13
Cytoband	Ensembl 112 genes in cytogenetic band chr1q23	OR6N2 OR6K2 OR10J3 OR6N1	1.44e-03	226	98	4	chr1q23
GeneFamily	Olfactory receptors, family 1	OR1A2 OR1D4 OR1D2 OR1F1 OR1N2 OR1D5 OR1E3	1.31e-10	40	68	7	147
GeneFamily	Olfactory receptors, family 6	OR6N2 OR6K2 OR6X1 OR6N1 OR6C76	1.33e-06	51	68	5	153
GeneFamily	Olfactory receptors, family 4	OR4C6 OR4M1 OR4K14 OR4M2	1.42e-03	129	68	4	151
Disease	Insulinogenic index measurement	MYCBP2 PPIP5K2	8.35e-05	5	86	2	EFO_0009961
Disease	glomerular filtration rate, renal transplant outcome measurement	OR1D4 NBAS OR1D5	1.46e-04	35	86	3	EFO_0005199, EFO_0005208
Disease	hydrocephalus (implicated_via_orthology)	STK36 HYDIN	1.39e-03	19	86	2	DOID:10908 (implicated_via_orthology)
Disease	systemising measurement	ERLEC1 NBAS	1.70e-03	21	86	2	EFO_0010221
Disease	Primary microcephaly	CIT KNL1	1.87e-03	22	86	2	C0431350
Disease	Autosomal Recessive Primary Microcephaly	CIT KNL1	1.87e-03	22	86	2	C3711387

Protein segments in the cluster

Peptide	Gene	Start	Entry
PRSSTVMYICHPESK	ERLEC1	206	Q96DZ1
SPHAVTVYMLEPHSC	ERLEC1	441	Q96DZ1
EVPIVSPICRFTYHM	ERVK-9	181	Q9UKH3
PTSVLSCPSYEEVMH	ANKRD11	1706	Q6UB99
CPDDTLISFLPLAHM	ACSL1	311	P33121
ICMSPESYLGSPQHS	ATF4	221	P18848
PVDCSHRSPEYSTAM	A2ML1	691	A8K2U0
GSLPLISVPYSMHCC	ADCY4	711	Q8NFM4
VPLSEPVTMDKVHYC	AQR	236	O60306
YHSVVSCAAVVLTPM	CCSER1	541	Q9C0I3
VPYILKMESHPHTTC	CIT	1521	O14578
CSPLHYPSIMTPKLC	OR6K2	126	Q8NGY2
LLVYLMPPCHSDTLE	ARHGAP36	331	Q6ZRI8
ICTISLDPHLTSPMY	OR4M2B	46	A0A0X1KG70
RETTMLPYHIPHLAC	LTN1	1551	O94822
HYPTLMTPTLCAEIA	OR6N1	131	Q8NGY5
ISCPLHYTTIMSPRS	OR1A2	126	Q9Y585
ASCSPIIMPYKAAHS	MAP7	251	Q14244
YMTHPTQAICPILLE	INTS11	91	Q5TA45
FVCTMAYPTVPCPLH	LONRF1	571	Q17RB8
PCELTYKVPTRHSMS	CFAP65	1146	Q6ZU64
LHPCMFPLATAYSTL	POLD2	311	P49005
LVTVISDPCLHSSPM	OR4K14	46	Q8NGD5
ICTIRLDPHLTSPMY	OR4M1	46	Q8NGD0
ICTISLDPHLTSPMY	OR4M2	46	Q8NGB6
TVPYRLCSSPVSMVH	MSTO1	341	Q9BUK6
HSPPEMEICTVYLTK	PDZD2	61	O15018
AICTLLMPYHKPDSS	KDM4C	646	Q9H3R0
LSNPTPDYCHDKMII	KNL1	766	Q8NG31
PHTAPCEVRVLMLLY	MED25	501	Q71SY5
ISMYVCPSPHLLPEI	OR11L1	256	Q8NGX0
ICYTPTFVPLMLVHL	OR13J1	71	Q8NGT2
YLTICNPLHHPTIMT	OR6X1	121	Q8NH79
ELMAFALTHCPPSSI	NBAS	1336	A2RRP1
VAICKPLHYTTIMSD	OR6C76	121	A6NM76
YPSSQEDPIHIACMA	HIDE1	26	A8MVS5
YTPSSDMVLHPVCHV	MTMR4	546	Q9NYA4
NPSHCLVYKVPSASM	NPHP4	416	O75161
SLTIPCYFIDPMHPV	ACAN	46	P16112
CYFIDPMHPVTTAPS	ACAN	51	P16112
ILSVSIDSCLHTPMY	OR1F1	46	O43749
YELHMKSTPCPETLD	PLA2G4E	316	Q3MJ16
LPYPTMSETMAVCSH	ORC1	811	Q13415
ICRPLHYPIIMTTTL	OR6N2	126	Q8NGY6
GMPESLLYCSLHDPV	QTRT2	86	Q9H974
PMSIDCLYTNTTHLE	HYDIN	4346	Q4G0P3
SLLAMYNHLTTCEPP	CABIN1	276	Q9Y6J0
LALSIYPPMCHLTVR	CCNDBP1	291	O95273
MHPDLGPLCTLLYVT	CDON	1	Q4KMG0
STCAAMPKLHEPYAS	CCP110	496	O43303
SPIHTLCYMREPILD	INPP5B	786	P32019
LVALMEASLTYPSHC	FSHR	261	P23945
HTVSMDTLPPYEAVC	BEAN1	206	Q3B7T3
ECSHLPAVMPAFTVY	PRDM13	451	Q9H4Q3
LHPLYVMLPCTLATS	SLC13A2	496	Q13183
MPHVIEITLPMLCSY	RYR1	3266	P21817
TVAVAFTPTIPHCSM	CIAO2B	81	Q9Y3D0
ESILPRPHASIMFCT	DHX9	476	Q08211
ICAHPASMSVTPVYK	NUP210L	756	Q5VU65
ICFPLHYTTIMSPKC	OR1E3	126	Q8WZA6
FKHIYNMDPSTSVPC	LAMA4	1021	Q16363
NLTVMCPSIDPLHYH	OMD	316	Q99983
RTFVPASSPMYHTCV	PGAP3	126	Q96FM1
CPPHSLTYMEATSVC	EPHA6	296	Q9UF33
ICCPLHYTTAMSPKL	OR1D2	126	P34982
ICCPLHYVTAMSPGL	OR1D4	126	P47884
TCCPLHYVTAMSPGL	OR1D5	126	P58170
ETCYTVAIIPHMLSG	OR10J3	71	Q5JRS4
VAICQPLHYSTSMSP	OR1N2	141	Q8NGR9
PLHYSTSMSPQLCAL	OR1N2	146	Q8NGR9
KPLHYTIIMSPRVCC	OR4C6	126	Q8NH72
PAMASAIECHSPYTS	FOXF2	321	Q12947
TLDCIMTYKHPHVLP	UTP20	956	O75691
YEITLLSPCLHMLPH	KARS1	201	Q15046
FKPDATYHTMNTIPC	POU4F2	136	Q12837
CMPHYDIDSASVPSL	PRC1	136	O43663
FYCPHCLVAMEPVST	SHPRH	701	Q149N8
AVIESEHPYKPACVM	MYCBP2	2021	O75592
PLSCISTADLHKMYP	MED13	821	Q9UHV7
MYSSPLCLTQDEFHP	NFIC	1	P08651
CLSQLYDHMPEGLTP	RHPN2	381	Q8IUC4
CCYHLPLMQVELPIS	STK36	1021	Q9NRP7
QLPCKTRPHSLMIYS	NEU3	191	Q9UQ49
PVTMLTACYSLICHE	AVPR1B	211	P47901
PSEVEHMFSPSCVSL	PGF	66	P49763
TPAHVLPSAAFLCSM	WDR75	736	Q8IWA0
HYNVKMPPTSSVTSC	STPG4	181	Q8N801
SMPCVLFAASPSELH	RTCA	106	O00442
CLSQLYDHMPEGLTP	RHPN2P1	296	A8MT19
CLPGVIMSVHPRYIS	USP9Y	1006	O00507
MHVFCTYLDSRLPPH	TMEM209	451	Q96SK2
PCVHVYVTVGLMDPL	USP41	16	Q3LFD5
LYSMVPSICPLETLH	PPIP5K2	1121	O43314
VASVCIHSTVLSPPM	WNK1	966	Q9H4A3
HDCMFLDPPYSRVIT	PJA2	371	O43164
LLPCTALVEHMTETY	SNAPC2	246	Q13487
GCSMVPTIYPLETLH	PPIP5K1	1086	Q6PFW1
SHYLCHEVAPPRLVM	TYK2	431	P29597
LPLYRTCHPIMPVAS	USP54	1066	Q70EL1
PRIHTVLSGEVYTCM	VPS13D	2271	Q5THJ4
CTMAYPTVPCPLHIF	LONRF3	561	Q496Y0
TVPYHCVTPMASIQS	NACA	211	E9PAV3
CTEQEMPRYHELPTL	NECTIN2	446	Q92692