Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix constituent, lubricant activity	MUC17 MUC3A MUC4	2.20e-07	4	77	3	GO:0030197
GeneOntologyMolecularFunction	neuroligin family protein binding	NRXN3 NRXN1 NRXN2	5.48e-07	5	77	3	GO:0097109
GeneOntologyMolecularFunction	transcription factor binding	NCOA2 CCNT1 NCOR1 TEAD2 FOXP2 PITX1 PITX2 HCFC1 LRIF1 ZNF568 TP53BP1 HTT	2.93e-05	753	77	12	GO:0008134
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	NCOA2 CCNT1 NCOR1 FOXP2 PITX1 PITX2 HCFC1 LRIF1 TP53BP1	3.95e-04	582	77	9	GO:0140297
GeneOntologyMolecularFunction	ion channel regulator activity	NRXN3 ANK2 NRXN1 NRXN2 WNK2	4.08e-04	162	77	5	GO:0099106
GeneOntologyMolecularFunction	channel regulator activity	NRXN3 ANK2 NRXN1 NRXN2 WNK2	5.65e-04	174	77	5	GO:0016247
GeneOntologyMolecularFunction	transporter regulator activity	NRXN3 ANK2 NRXN1 NRXN2 WNK2	6.10e-04	177	77	5	GO:0141108
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	NCOA2 NCOR1 FOXP2 PITX1 PITX2 LRIF1 TP53BP1	1.13e-03	417	77	7	GO:0061629
GeneOntologyMolecularFunction	calcium channel regulator activity	NRXN3 NRXN1 NRXN2	1.19e-03	54	77	3	GO:0005246
GeneOntologyMolecularFunction	nuclear retinoic acid receptor binding	NCOA2 NCOR1 LRIF1	1.25e-03	55	77	3	GO:0042974
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR51F2 NRXN3 NRXN1 NRXN2 SPN GPR34 OR1L6 ROBO1 ADGRF5 TNFRSF1B ADGRG4 OR51H1 OR1L4	1.88e-03	1353	77	13	GO:0004888
GeneOntologyMolecularFunction	protein domain specific binding	NCOA2 NCOR1 TEAD2 LNX2 SPN MUC17 CHMP1B SHCBP1 ROBO1 CHMP1A	1.90e-03	875	77	10	GO:0019904
GeneOntologyBiologicalProcess	vocal learning	NRXN1 FOXP2 NRXN2 HTT	5.91e-09	7	76	4	GO:0042297
GeneOntologyBiologicalProcess	imitative learning	NRXN1 FOXP2 NRXN2 HTT	5.91e-09	7	76	4	GO:0098596
GeneOntologyBiologicalProcess	observational learning	NRXN1 FOXP2 NRXN2 HTT	2.11e-08	9	76	4	GO:0098597
GeneOntologyBiologicalProcess	learned vocalization behavior or vocal learning	NRXN1 FOXP2 NRXN2 HTT	5.51e-08	11	76	4	GO:0098598
GeneOntologyBiologicalProcess	auditory behavior	NRXN1 FOXP2 NRXN2 HTT	1.66e-07	14	76	4	GO:0031223
GeneOntologyBiologicalProcess	mechanosensory behavior	NRXN1 FOXP2 NRXN2 HTT	3.91e-07	17	76	4	GO:0007638
GeneOntologyBiologicalProcess	vocalization behavior	NRXN3 NRXN1 FOXP2 NRXN2	1.71e-06	24	76	4	GO:0071625
GeneOntologyBiologicalProcess	response to auditory stimulus	NRXN1 FOXP2 NRXN2 HTT	1.02e-05	37	76	4	GO:0010996
GeneOntologyBiologicalProcess	neuron cell-cell adhesion	NRXN3 NRXN1 NRXN2	2.60e-05	16	76	3	GO:0007158
GeneOntologyBiologicalProcess	neuroligin clustering involved in postsynaptic membrane assembly	NRXN1 NRXN2	8.00e-05	4	76	2	GO:0097118
GeneOntologyBiologicalProcess	cellular response to Thyroglobulin triiodothyronine	NCOA2 NCOR1	8.00e-05	4	76	2	GO:1904017
GeneOntologyBiologicalProcess	membrane assembly	NRXN1 NRXN2 CHMP1B CHMP1A	9.15e-05	64	76	4	GO:0071709
GeneOntologyBiologicalProcess	gephyrin clustering involved in postsynaptic density assembly	NRXN1 NRXN2	1.33e-04	5	76	2	GO:0097116
GeneOntologyBiologicalProcess	membrane biogenesis	NRXN1 NRXN2 CHMP1B CHMP1A	1.53e-04	73	76	4	GO:0044091
GeneOntologyBiologicalProcess	social behavior	NRXN3 NRXN1 NRXN2 HTT	1.61e-04	74	76	4	GO:0035176
GeneOntologyBiologicalProcess	biological process involved in intraspecies interaction between organisms	NRXN3 NRXN1 NRXN2 HTT	1.79e-04	76	76	4	GO:0051703
GeneOntologyBiologicalProcess	response to Thyroglobulin triiodothyronine	NCOA2 NCOR1	1.99e-04	6	76	2	GO:1904016
GeneOntologyBiologicalProcess	postsynaptic density assembly	NRXN3 NRXN1 NRXN2	2.65e-04	34	76	3	GO:0097107
GeneOntologyBiologicalProcess	axon midline choice point recognition	ROBO1 FOXG1	2.78e-04	7	76	2	GO:0016199
GeneOntologyBiologicalProcess	neural plate morphogenesis	ZNF568 HTT	4.74e-04	9	76	2	GO:0001839
GeneOntologyBiologicalProcess	axon choice point recognition	ROBO1 FOXG1	4.74e-04	9	76	2	GO:0016198
GeneOntologyBiologicalProcess	postsynaptic specialization assembly	NRXN3 NRXN1 NRXN2	5.71e-04	44	76	3	GO:0098698
GeneOntologyBiologicalProcess	regulation of organelle assembly	ALMS1 NRXN1 CHMP1B MCIDAS HTT CHMP1A	5.85e-04	280	76	6	GO:1902115
GeneOntologyBiologicalProcess	ESCRT III complex disassembly	CHMP1B CHMP1A	5.92e-04	10	76	2	GO:1904903
GeneOntologyBiologicalProcess	positive regulation of synapse maturation	NRXN1 CAMK2B	5.92e-04	10	76	2	GO:0090129
GeneOntologyBiologicalProcess	ESCRT complex disassembly	CHMP1B CHMP1A	5.92e-04	10	76	2	GO:1904896
GeneOntologyCellularComponent	Golgi lumen	MUC3B MUC17 MUC16 MUC5B MUC3A MUC4	4.77e-06	109	83	6	GO:0005796
MousePheno	abnormal breathing pattern	SOX6 NRXN1 FOXP2 ADGRF5 MUC5B MUC4 TMEM38B FOXG1	4.82e-05	303	61	8	MP:0001951
MousePheno	abnormal response to social novelty	ARHGAP32 HIVEP2 MIGA2 CBARP	6.00e-05	49	61	4	MP:0020395
MousePheno	abnormal social/conspecific interaction behavior	ARHGAP32 HIVEP2 MIGA2 ANK2 NRXN1 NRXN2 CAMK2B CBARP HTT	8.09e-05	421	61	9	MP:0002557
Domain	SEA	MUC3B MUC17 MUC16 ADGRF5 MUC3A IMPG2	1.18e-11	14	77	6	SM00200
Domain	SEA	MUC3B MUC17 MUC16 ADGRF5 MUC3A IMPG2	3.84e-10	23	77	6	PS50024
Domain	SEA_dom	MUC3B MUC17 MUC16 ADGRF5 MUC3A IMPG2	3.84e-10	23	77	6	IPR000082
Domain	SEA	MUC3B MUC17 MUC16 ADGRF5 IMPG2	2.60e-08	22	77	5	PF01390
Domain	Neurexin-like	NRXN3 NRXN1 NRXN2 GYPC	2.59e-07	14	77	4	IPR003585
Domain	4.1m	NRXN3 NRXN1 NRXN2 GYPC	2.59e-07	14	77	4	SM00294
Domain	LRRC37AB_C	LRRC37A LRRC37A3 LRRC37A2	2.69e-07	4	77	3	PF14914
Domain	LRRC37_N	LRRC37A LRRC37A3 LRRC37A2	2.69e-07	4	77	3	IPR032754
Domain	LRRC37AB_C	LRRC37A LRRC37A3 LRRC37A2	2.69e-07	4	77	3	IPR029423
Domain	LRRC37	LRRC37A LRRC37A3 LRRC37A2	2.69e-07	4	77	3	PF15779
Domain	LRRC37A/B-like	LRRC37A LRRC37A3 LRRC37A2	2.69e-07	4	77	3	IPR015753
Domain	-	MUC17 MUC16 ADGRF5 IMPG2	3.52e-07	15	77	4	3.30.70.960
Domain	Syndecan	NRXN3 NRXN1 NRXN2	2.33e-06	7	77	3	PF01034
Domain	Syndecan/Neurexin_dom	NRXN3 NRXN1 NRXN2	2.33e-06	7	77	3	IPR027789
Domain	EGF_3	MUC3B NRXN3 NRXN1 NRXN2 MUC17 MUC3A MUC4 IMPG2	5.56e-06	235	77	8	PS50026
Domain	EGF-like_dom	MUC3B NRXN3 NRXN1 NRXN2 MUC17 MUC3A MUC4 IMPG2	8.49e-06	249	77	8	IPR000742
Domain	EGF_1	MUC3B NRXN3 NRXN1 NRXN2 MUC17 MUC3A MUC4 IMPG2	1.01e-05	255	77	8	PS00022
Domain	EGF-like_CS	MUC3B NRXN3 NRXN1 NRXN2 MUC17 MUC3A MUC4 IMPG2	1.20e-05	261	77	8	IPR013032
Domain	EGF_2	MUC3B NRXN3 NRXN1 NRXN2 MUC17 MUC3A MUC4 IMPG2	1.33e-05	265	77	8	PS01186
Domain	-	NRXN3 NRXN1 NRXN2 LRBA ADGRG4	4.53e-05	95	77	5	2.60.120.200
Domain	Homeobox_Pitx/unc30	PITX1 PITX2	5.02e-05	3	77	2	IPR016233
Domain	EGF	MUC3B NRXN3 NRXN1 NRXN2 MUC17 MUC3A MUC4	5.20e-05	235	77	7	SM00181
Domain	LAM_G_DOMAIN	NRXN3 NRXN1 NRXN2	5.12e-04	38	77	3	PS50025
Domain	Laminin_G_2	NRXN3 NRXN1 NRXN2	5.96e-04	40	77	3	PF02210
Domain	LamG	NRXN3 NRXN1 NRXN2	7.90e-04	44	77	3	SM00282
Domain	Snf7_fam	CHMP1B CHMP1A	1.08e-03	12	77	2	IPR005024
Domain	Snf7	CHMP1B CHMP1A	1.08e-03	12	77	2	PF03357
Domain	OAR	PITX1 PITX2	1.70e-03	15	77	2	PF03826
Domain	Laminin_G	NRXN3 NRXN1 NRXN2	1.77e-03	58	77	3	IPR001791
Domain	EGF	NRXN3 NRXN1 NRXN2 MUC4	1.83e-03	126	77	4	PF00008
Domain	OAR	PITX1 PITX2	1.94e-03	16	77	2	PS50803
Domain	VWD	MUC5B MUC4	1.94e-03	16	77	2	SM00216
Domain	VWF_type-D	MUC5B MUC4	1.94e-03	16	77	2	IPR001846
Domain	VWFD	MUC5B MUC4	1.94e-03	16	77	2	PS51233
Domain	OAR_dom	PITX1 PITX2	1.94e-03	16	77	2	IPR003654
Domain	VWD	MUC5B MUC4	1.94e-03	16	77	2	PF00094
Domain	ConA-like_dom	NRXN3 NRXN1 NRXN2 LRBA ADGRG4	2.11e-03	219	77	5	IPR013320
Pathway	REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC	MUC17 MUC16 MUC5B MUC3A MUC4	4.17e-09	16	58	5	M27410
Pathway	REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS	MUC17 MUC16 MUC5B MUC3A MUC4	5.89e-09	17	58	5	M27412
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC17 MUC16 MUC5B MUC3A MUC4	3.14e-08	23	58	5	M556
Pathway	REACTOME_DECTIN_2_FAMILY	MUC17 MUC16 MUC5B MUC3A MUC4	6.09e-08	26	58	5	M27483
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC17 MUC16 MUC5B MUC4	1.47e-06	21	58	4	MM15706
Pathway	WP_HIPPOCAMPAL_SYNAPTOGENESIS_AND_NEUROGENESIS	NRXN3 NRXN1 NRXN2 CAMK2B	4.22e-06	27	58	4	M45550
Pathway	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	MUC17 MUC16 MUC5B MUC3A MUC4	5.35e-06	62	58	5	M546
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	MUC17 MUC16 MUC5B MUC3A MUC4	8.46e-06	68	58	5	M27303
Pathway	REACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY	NCOR1 CAMK2B FOXG1 HTT	8.51e-06	32	58	4	M27900
Pathway	WP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV	NRXN3 NRXN1 NRXN2 CAMK2B	9.66e-06	33	58	4	M39875
Pathway	WP_RETT_SYNDROME	NCOR1 HIVEP2 FOXG1 HTT	4.39e-05	48	58	4	M39759
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	MUC17 MUC16 MUC5B MUC3A MUC4	9.09e-05	111	58	5	M27416
Pathway	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	MUC17 MUC16 MUC5B MUC4	1.06e-04	60	58	4	MM15636
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2	NCOR1 CAMK2B FOXG1 HTT	1.28e-04	63	58	4	M27862
Pathway	REACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS	MUC17 MUC16 MUC5B MUC3A MUC4	2.70e-04	140	58	5	M27484
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	MUC17 MUC16 MUC5B MUC3A MUC4	2.98e-04	143	58	5	M27275
Pathway	REACTOME_NEUREXINS_AND_NEUROLIGINS	NRXN3 NRXN1 NRXN2	3.01e-04	32	58	3	MM15326
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	MUC17 MUC16 MUC5B MUC4	1.04e-03	109	58	4	MM15164
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC17 MUC16 MUC5B MUC3A MUC4	5.73e-10	18	83	5	18834073
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NCOA2 NCOR1 ARHGAP32 PDE4A ANK2 NRXN1 FOXP2 CAMK2B HECTD4 PRKCI ZNF318 MTCL1 HUWE1 FOXG1 WNK2 TP53BP1	9.63e-10	963	83	16	28671696
Pubmed	Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	34133920
Pubmed	Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca2+ Influx.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	38891114
Pubmed	The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	30858964
Pubmed	Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	28013231
Pubmed	alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	16406382
Pubmed	Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	31812984
Pubmed	Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.	MUC3B MUC17 MUC3A	1.31e-08	3	83	3	10512748
Pubmed	Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	12036300
Pubmed	β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	26213384
Pubmed	Neurexin gene family variants as risk factors for autism spectrum disorder.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	29045040
Pubmed	Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	31005376
Pubmed	Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	38571813
Pubmed	Deletion of β-Neurexins in Mice Alters the Distribution of Dense-Core Vesicles in Presynapses of Hippocampal and Cerebellar Neurons.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	35173587
Pubmed	Neurexins are differentially expressed in the embryonic nervous system of mice.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	7722633
Pubmed	Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	26446217
Pubmed	Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	11944992
Pubmed	Alternative splicing of neurexins 1-3 is modulated by neuroinflammation in the prefrontal cortex of a murine model of multiple sclerosis.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	33058888
Pubmed	Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	17035546
Pubmed	Neurexins: three genes and 1001 products.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	9448462
Pubmed	Deletion of α-neurexin II results in autism-related behaviors in mice.	NRXN3 NRXN1 NRXN2	1.31e-08	3	83	3	25423136
Pubmed	Postsynaptic N-methyl-D-aspartate receptor function requires alpha-neurexins.	NRXN3 NRXN1 NRXN2	5.23e-08	4	83	3	14983056
Pubmed	Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism.	NRXN3 NRXN1 NRXN2	5.23e-08	4	83	3	32706374
Pubmed	CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins.	NRXN3 NRXN1 NRXN2	5.23e-08	4	83	3	8786425
Pubmed	Deletion of alpha-neurexins does not cause a major impairment of axonal pathfinding or synapse formation.	NRXN3 NRXN1 NRXN2	5.23e-08	4	83	3	17347997
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A LRRC37A3 LRRC37A2	5.23e-08	4	83	3	22419166
Pubmed	Neurexins cluster Ca2+ channels within the presynaptic active zone.	NRXN3 NRXN1 NRXN2	5.23e-08	4	83	3	32134527
Pubmed	Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins.	NRXN3 NRXN1 NRXN2	5.23e-08	4	83	3	35385735
Pubmed	Neurexins regulate presynaptic GABAB-receptors at central synapses.	NRXN3 NRXN1 NRXN2	5.23e-08	4	83	3	33888718
Pubmed	Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins.	NRXN3 NRXN1 NRXN2	1.31e-07	5	83	3	28472659
Pubmed	Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.	NRXN3 NRXN1 NRXN2	1.31e-07	5	83	3	36709330
Pubmed	Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum.	NRXN3 NRXN1 NRXN2	1.31e-07	5	83	3	20537373
Pubmed	Neuroligins and neurexins link synaptic function to cognitive disease.	NRXN3 NRXN1 NRXN2	1.31e-07	5	83	3	18923512
Pubmed	Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration.	NRXN3 NRXN1 NRXN2	1.31e-07	5	83	3	9223334
Pubmed	Interaction network of human early embryonic transcription factors.	NCOA2 NCOR1 HIVEP2 ALMS1 FOXP2 MCM3AP PITX1 PITX2 LRIF1	1.67e-07	351	83	9	38297188
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	NRXN3 LRRC37A NRXN1 LRRC37A3 MCM3AP PACS2	2.05e-07	105	83	6	9628581
Pubmed	Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.	NRXN3 NRXN1 NRXN2	2.61e-07	6	83	3	12827191
Pubmed	Structures, alternative splicing, and neurexin binding of multiple neuroligins.	NRXN3 NRXN1 NRXN2	2.61e-07	6	83	3	8576240
Pubmed	Presynaptic α2δ-2 Calcium Channel Subunits Regulate Postsynaptic GABAA Receptor Abundance and Axonal Wiring.	NRXN3 NRXN1 NRXN2	2.61e-07	6	83	3	30683685
Pubmed	Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.	NRXN3 NRXN1 NRXN2	7.28e-07	8	83	3	30871858
Pubmed	Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.	NRXN3 NRXN1 NRXN2	7.28e-07	8	83	3	37591863
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NCOA2 NCOR1 ALMS1 ZNF318 HUWE1 LRBA PRPF40A HCFC1 TP53BP1 HTT	7.67e-07	549	83	10	38280479
Pubmed	Molecular self-avoidance in synaptic neurexin complexes.	NRXN3 NRXN1 NRXN2	1.09e-06	9	83	3	34919427
Pubmed	PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.	NRXN3 NRXN1 NRXN2	1.09e-06	9	83	3	9707552
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A LRRC37A3 LRRC37A2	1.55e-06	10	83	3	23064749
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PCNX2 NCOR1 TEAD2 PDE4A HIVEP2 MCM3AP PITX1 HECTD4 HUWE1 LRBA HCFC1 WNK2 HTT	2.11e-06	1105	83	13	35748872
Pubmed	SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.	NRXN3 NRXN1 NRXN2	2.13e-06	11	83	3	32973045
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ARHGAP32 NRXN3 ADGRF5 MTCL1 TMCC1	4.53e-06	101	83	5	9872452
Pubmed	The contribution of rare and common variants in 30 genes to risk nicotine dependence.	NRXN3 NRXN1 NRXN2	4.68e-06	14	83	3	25450229
Pubmed	Enhancer interaction networks as a means for singular olfactory receptor expression.	OR1L6 FOXG1 OR1L4	4.68e-06	14	83	3	25417106
Pubmed	Floor-plate-derived netrin-1 is dispensable for commissural axon guidance.	FOXP2 ROBO1 FOXG1	4.68e-06	14	83	3	28445456
Pubmed	CaMKII inhibition due to TRIC-B loss-of-function dysregulates SMAD signaling in osteogenesis imperfecta.	CAMK2B TMEM38B	5.63e-06	2	83	2	37178987
Pubmed	Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus.	MUC3B MUC3A	5.63e-06	2	83	2	12958310
Pubmed	Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus.	NRXN3 NRXN1	5.63e-06	2	83	2	37543682
Pubmed	Neurexin I alpha is a major alpha-latrotoxin receptor that cooperates in alpha-latrotoxin action.	NRXN3 NRXN1	5.63e-06	2	83	2	9430716
Pubmed	Otlx2, an Otx-related homeobox gene expressed in the pituitary gland and in a restricted pattern in the forebrain.	PITX1 PITX2	5.63e-06	2	83	2	9026314
Pubmed	Mutations in NRXN1 and NRXN2 in a patient with early-onset epileptic encephalopathy and respiratory depression.	NRXN1 NRXN2	5.63e-06	2	83	2	30709877
Pubmed	Interaction with polyglutamine-expanded huntingtin alters cellular distribution and RNA processing of huntingtin yeast two-hybrid protein A (HYPA).	PRPF40A HTT	5.63e-06	2	83	2	21566141
Pubmed	Pitx genes during cardiovascular development.	PITX1 PITX2	5.63e-06	2	83	2	12858527
Pubmed	Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B.	MUC3B MUC3A	5.63e-06	2	83	2	10973822
Pubmed	Association of a polymorphism in the NRXN3 gene with the degree of smoking in schizophrenia: a preliminary study.	NRXN3 NRXN1	5.63e-06	2	83	2	19658047
Pubmed	MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region.	MUC3B MUC3A	5.63e-06	2	83	2	9334251
Pubmed	Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1).	CCNT1 PRKCI	5.63e-06	2	83	2	19208825
Pubmed	Molecular cloning of cDNAs derived from a novel human intestinal mucin gene.	MUC3B MUC3A	5.63e-06	2	83	2	2393399
Pubmed	Postnatal Foxp2 regulates early psychiatric-like phenotypes and associated molecular alterations in the R6/1 transgenic mouse model of Huntington's disease.	FOXP2 HTT	5.63e-06	2	83	2	36029989
Pubmed	Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease.	MUC3B MUC3A	5.63e-06	2	83	2	11289722
Pubmed	Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.	MUC16 MUC4	5.63e-06	2	83	2	23544943
Pubmed	Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin.	NRXN1 NRXN2	5.63e-06	2	83	2	1621094
Pubmed	Heterozygous deletion of α-neurexin I or α-neurexin II results in behaviors relevant to autism and schizophrenia.	NRXN1 NRXN2	5.63e-06	2	83	2	26595880
Pubmed	Expression of mucins in mucoid otitis media.	MUC5B MUC4	5.63e-06	2	83	2	14690056
Pubmed	Increased Levels of Rictor Prevent Mutant Huntingtin-Induced Neuronal Degeneration.	RICTOR HTT	5.63e-06	2	83	2	29460266
Pubmed	The MUC3 gene encodes a transmembrane mucin and is alternatively spliced.	MUC3B MUC3A	5.63e-06	2	83	2	10405327
Pubmed	Expression of the members of the Ptx family of transcription factors in human pituitary adenomas.	PITX1 PITX2	5.63e-06	2	83	2	10372733
Pubmed	Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles.	NCOR1 PRPF40A HTT	5.84e-06	15	83	3	11092755
Pubmed	Human transcription factor protein interaction networks.	SOX6 NCOA2 NCOR1 SP2 ARHGAP32 TEAD2 ALMS1 FOXP2 PITX1 ZNF318 PRPF40A HCFC1 LRIF1 TP53BP1	6.82e-06	1429	83	14	35140242
Pubmed	Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain.	NCOR1 PITX1 PITX2 FOXG1	1.08e-05	57	83	4	21122108
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	NCOA2 NCOR1 ALMS1 CAMK2B MCM3AP ZNF318 HUWE1 LRIF1 TP53BP1	1.15e-05	588	83	9	38580884
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	ARHGAP32 ALMS1 NRXN1 NRXN2 MCM3AP	1.55e-05	130	83	5	12421765
Pubmed	Paired-like homeodomain transcription factors 1 and 2 regulate follicle-stimulating hormone beta-subunit transcription through a conserved cis-element.	PITX1 PITX2	1.69e-05	3	83	2	18339718
Pubmed	The bicoid-related Pitx gene family in development.	PITX1 PITX2	1.69e-05	3	83	2	9922405
Pubmed	PDCD2 is a negative regulator of HCF-1 (C1).	NCOR1 HCFC1	1.69e-05	3	83	2	12149646
Pubmed	Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.	MUC16 MUC4	1.69e-05	3	83	2	23053434
Pubmed	Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors.	NCOA2 NCOR1	1.69e-05	3	83	2	24550004
Pubmed	Interaction of the nuclear matrix protein NAKAP with HypA and huntingtin: implications for nuclear toxicity in Huntington's disease pathogenesis.	PRPF40A HTT	1.69e-05	3	83	2	16391387
Pubmed	Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia.	NRXN1 NRXN2	1.69e-05	3	83	2	21424692
Pubmed	DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.	MUC16 MUC5B	1.69e-05	3	83	2	27230679
Pubmed	Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.	MUC16 MUC4	1.69e-05	3	83	2	30236127
Pubmed	Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.	MUC3B MUC3A	1.69e-05	3	83	2	18163520
Pubmed	CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression.	CHMP1B CHMP1A	1.69e-05	3	83	2	11559747
Pubmed	Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.	MUC16 MUC4	1.69e-05	3	83	2	17592322
Pubmed	PITX2 AND PITX1 regulate thyrotroph function and response to hypothyroidism.	PITX1 PITX2	1.69e-05	3	83	2	21964592
Pubmed	Two atypical enteropathogenic Escherichia coli strains induce the production of secreted and membrane-bound mucins to benefit their own growth at the apical surface of human mucin-secreting intestinal HT29-MTX cells.	MUC17 MUC4	1.69e-05	3	83	2	20065027
Pubmed	Mutant huntingtin increases nuclear corepressor function and enhances ligand-dependent nuclear hormone receptor activation.	NCOR1 HTT	1.69e-05	3	83	2	12799135
Pubmed	Language development and disorders: Possible genes and environment interactions.	FOXP2 ROBO1	1.69e-05	3	83	2	30077386
Pubmed	Pitx factors are involved in basal and hormone-regulated activity of the human prolactin promoter.	PITX1 PITX2	1.69e-05	3	83	2	12223489
Pubmed	Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.	MUC16 MUC4	1.69e-05	3	83	2	35879412
Pubmed	Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).	MUC16 MUC4	1.69e-05	3	83	2	27483328
Pubmed	MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.	MUC16 MUC4	1.69e-05	3	83	2	24204560
Pubmed	Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.	MUC16 MUC4	1.69e-05	3	83	2	24939955
Interaction	YWHAH interactions	NCOA2 ARHGAP32 HIVEP2 ALMS1 SHCBP1 HECTD4 PACS2 RICTOR PRKCI CBARP MTCL1 HUWE1 LRBA TMCC1 WNK2 HTT	3.34e-06	1102	77	16	int:YWHAH
Interaction	WWTR1 interactions	NCOA2 NCOR1 TEAD2 ALMS1 ZNF318 LRBA PRPF40A HCFC1 TP53BP1 HTT	4.57e-06	422	77	10	int:WWTR1
Interaction	YWHAZ interactions	NCOR1 ARHGAP32 LNX2 HIVEP2 NRXN1 CAMK2B SHCBP1 HECTD4 PACS2 RICTOR PRKCI CBARP HUWE1 TMCC1 WNK2 TP53BP1 HTT	7.69e-06	1319	77	17	int:YWHAZ
Interaction	YWHAG interactions	ARHGAP32 LNX2 HIVEP2 ALMS1 SHCBP1 HECTD4 PACS2 RICTOR PRKCI CBARP MTCL1 HUWE1 LRBA PRPF40A TMCC1 HTT	1.60e-05	1248	77	16	int:YWHAG
Interaction	CCNT1 interactions	NCOA2 CCNT1 RICTOR PRKCI TNFRSF1B PRPF40A TP53BP1	2.44e-05	225	77	7	int:CCNT1
Interaction	C6orf141 interactions	NCOR1 ALMS1 CAMK2B RICTOR ZNF318	2.71e-05	92	77	5	int:C6orf141
Interaction	NR2F1 interactions	NCOA2 TEAD2 FOXP2 FOXG1	7.15e-05	58	77	4	int:NR2F1
Interaction	NLGN1 interactions	NRXN3 NRXN1 NRXN2	7.84e-05	22	77	3	int:NLGN1
Interaction	SATB1 interactions	SOX6 TEAD2 FOXP2 FOXG1 HTT	8.23e-05	116	77	5	int:SATB1
Interaction	B4GALT2 interactions	NCOR1 ARHGAP32 MCM3AP RICTOR ZNF318	9.28e-05	119	77	5	int:B4GALT2
GeneFamily	CD molecules\|Mucins	MUC3B MUC17 MUC16 MUC5B MUC22 MUC3A MUC4	1.39e-13	21	53	7	648
GeneFamily	Charged multivesicular body proteins\|ESCRT-III associated factors	CHMP1B CHMP1A	8.38e-05	5	53	2	1119
GeneFamily	Charged multivesicular body proteins\|ESCRT-III associated factors	CHMP1B CHMP1A	4.56e-04	11	53	2	482
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HDA	NRXN3 SEMA6D ANK2 NRXN1 FOXP2 NRXN2 CAMK2B RTL9 MUC16 ROBO1 ZNF568	3.93e-07	506	80	11	M39067
Coexpression	NABA_ECM_AFFILIATED	SEMA6D MUC17 MUC16 MUC5B MUC22 MUC3A MUC4	9.10e-07	170	80	7	M5880
Coexpression	GSE25846_IL10_POS_VS_NEG_CD8_TCELL_DAY7_POST_CORONAVIRUS_BRAIN_UP	SPN LRRC37A2 MUC5B MTCL1 MUC3A ZFY	2.99e-05	195	80	6	M8140
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#2_top-relative-expression-ranked_500	NCOR1 FOXP2 MTCL1 HUWE1 PRPF40A RNF157	1.06e-05	132	80	6	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k2_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#3_top-relative-expression-ranked_1000	NCOR1 FOXP2 MTCL1 HUWE1 PRPF40A RNF157	1.37e-05	138	80	6	gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	SOX6 NCOA2 LNX2 NRXN3 ANK2 ALMS1 NRXN2 GYPC LRBA TMEM123 PRPF40A FOXG1 WNK2	7.32e-05	983	80	13	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
ToppCell	nucseq-Epithelial-Epithelial_Glandular\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC17 PITX1 MUC16 MUC5B MUC3A MUC4 WNK2 MGAM2	1.49e-09	179	82	8	859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC17 PITX1 MUC16 MUC5B MUC3A MUC4 WNK2 MGAM2	1.55e-09	180	82	8	3dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC17 PITX1 MUC16 MUC5B MUC3A MUC4 WNK2 MGAM2	1.55e-09	180	82	8	668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCell	Control-Epithelial_cells-Airway_goblet\|Control / group, cell type (main and fine annotations)	MUC17 PITX1 MUC16 MUC5B MUC3A MUC4 WNK2 MGAM2	1.85e-09	184	82	8	d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MCIDAS PITX1 MUC16 MUC5B SLC5A8 MUC4 WNK2	7.19e-08	194	82	7	e0228f593c3493175962a4817500d4337ddc4e88
ToppCell	proximal-3-Epithelial-Goblet\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MCIDAS PITX1 MUC16 MUC5B SLC5A8 MUC4 WNK2	8.27e-08	198	82	7	3477202c4f702d8f75231b13d4b5216f56d981d7
ToppCell	proximal-Epithelial-Goblet\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MCIDAS PITX1 MUC16 MUC5B SLC5A8 MUC4 WNK2	8.27e-08	198	82	7	e7e1c430486a81280abc4a7e7f5bc3713dd20737
ToppCell	proximal-Epithelial-Goblet-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MCIDAS PITX1 MUC16 MUC5B SLC5A8 MUC4 WNK2	8.27e-08	198	82	7	da7b40eb00bb5e454e1cfcd1219dc0d84712592a
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NRXN3 MCIDAS MUC16 MUC5B MUC4 WNK2	5.35e-07	161	82	6	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NRXN3 PITX1 MUC16 MUC5B MUC4 WNK2	8.14e-07	173	82	6	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	Fetal_29-31_weeks-Epithelial-lung_goblet_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NRXN3 MCIDAS MUC16 MUC5B SLC5A8 WNK2	9.31e-07	177	82	6	a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NRXN3 FOXP2 MCIDAS MUC5B MUC4 WNK2	9.31e-07	177	82	6	779ba86f53650772755b52460be03f18bb204e55
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NRXN3 FOXP2 MCIDAS MUC5B MUC4 WNK2	9.31e-07	177	82	6	0f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCell	Fetal_29-31_weeks-Epithelial-lung_goblet_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NRXN3 MCIDAS MUC16 MUC5B SLC5A8 WNK2	9.31e-07	177	82	6	363e07b0f347f3716d530a28ead854b98e27d37c
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP32 MUC16 MUC5B SLC5A8 MUC4 WNK2	9.94e-07	179	82	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	MUC17 MUC16 MUC5B MUC3A MUC4 MGAM2	1.13e-06	183	82	6	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	COVID-19-Epithelial_cells-Airway_goblet\|COVID-19 / group, cell type (main and fine annotations)	NRXN3 FOXP2 MUC16 MUC5B MUC4 WNK2	1.41e-06	190	82	6	51ca9ef4df3220487152fcf684147730637c7cc1
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCNX2 HIVEP2 NRXN3 NRXN2 CAMK2B CBARP	1.54e-06	193	82	6	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCNX2 HIVEP2 NRXN3 NRXN2 CAMK2B CBARP	1.54e-06	193	82	6	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCNX2 HIVEP2 NRXN3 NRXN2 CAMK2B CBARP	1.54e-06	193	82	6	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 PITX1 MUC16 MUC5B MUC4 WNK2	1.63e-06	195	82	6	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	NCOA2 ARHGAP32 FOXP2 LRRC37A3 LRBA TMCC1	1.79e-06	198	82	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	MCIDAS PITX1 MUC16 MUC5B MUC4 WNK2	1.79e-06	198	82	6	5dd2aa7684c36beffa204ca4c04d0501cabac10f
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NRXN3 MCIDAS MUC16 MUC5B MUC4 WNK2	1.79e-06	198	82	6	fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MCIDAS PITX1 MUC16 MUC5B SLC5A8 MUC4	1.84e-06	199	82	6	3c3133d0aa65338a576634def13e7f0f5c573a10
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MCIDAS PITX1 MUC16 MUC5B MUC4 WNK2	1.84e-06	199	82	6	a706ad5cd5e0dc8d7e925a05e45b07d35963f294
ToppCell	Biopsy_Control_(H.)-Epithelial-MUC5AC+_High\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	PITX1 MUC16 MUC5B SLC5A8 MUC4 WNK2	1.84e-06	199	82	6	a5240868cea40574ed4ee45eb27a00c1812957ed
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NRXN3 MCIDAS MUC16 MUC5B MUC4 WNK2	1.89e-06	200	82	6	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	NRXN3 NRXN2 CAMK2B HECTD4 WNK2 RNF157	1.89e-06	200	82	6	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	metastatic_Brain-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	CCNT1 LRRC37A MUC16 PRKCI TMCC1	1.20e-05	161	82	5	e6e294b4ba911c1327664f1a0f93207096c6de03
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B SLC5A8 FOXG1 WNK2 MGAM2	1.28e-05	163	82	5	a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell	5'-Airway_Nasal_SMG-Epithelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B SLC5A8 FOXG1 WNK2 MGAM2	1.28e-05	163	82	5	454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B SLC5A8 FOXG1 WNK2 MGAM2	1.28e-05	163	82	5	d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B SLC5A8 FOXG1 WNK2 MGAM2	1.28e-05	163	82	5	f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCell	5'-Airway_Nasal_SMG\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B SLC5A8 FOXG1 WNK2 MGAM2	1.28e-05	163	82	5	d8450bf9c6d2ec5dd1472952c9e65f82f995337a
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B SLC5A8 FOXG1 WNK2 MGAM2	1.28e-05	163	82	5	be6cc44df9a2b10dce1a353717c279c3558f8fec
ToppCell	Adult-Epithelial-lung_goblet_cell-D175\|Adult / Lineage, Cell type, age group and donor	PITX1 MUC16 MUC5B MUC4 WNK2	1.32e-05	164	82	5	6e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	ANK2 NRXN1 CAMK2B ROBO1 AMER3	1.36e-05	165	82	5	9795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SOX6 NRXN3 SEMA6D ANK2 NRXN1	1.48e-05	168	82	5	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	NS-critical-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TEAD2 ANK2 CAMK2B ROBO1 ADGRF5	1.48e-05	168	82	5	6a233045638cb83dab64789b996b7598c325001e
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	NRXN3 FOXP2 MUC16 MUC5B WNK2	1.75e-05	174	82	5	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NRXN3 MCIDAS PITX1 MUC16 MUC4	1.85e-05	176	82	5	8d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	NRXN3 FOXP2 MUC16 MUC5B WNK2	2.01e-05	179	82	5	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	droplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Hematologic-hematopoietic_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPN CBARP TMEM123 TNFRSF1B RNF157	2.01e-05	179	82	5	cb880ef40c203c8bd16c4f69a70cf59f97ebbffd
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCNX2 NRXN3 FOXP2 CAMK2B SLC24A1	2.01e-05	179	82	5	a3922476f33d2e4137a12dbda21a1703dff79684
ToppCell	droplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Hematologic\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPN CBARP TMEM123 TNFRSF1B RNF157	2.01e-05	179	82	5	686b9f745d290ca686b42d9505e9792c78667e6e
ToppCell	droplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Hematologic-hematopoietic_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPN CBARP TMEM123 TNFRSF1B RNF157	2.01e-05	179	82	5	1eb004e1a17e1f1e4337e0581e547c0f5a965e68
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CAMK2B PITX2 AMER3 SLC5A8 ADGRG4	2.06e-05	180	82	5	6b1606238417490e0d9930870a7827419d1c3737
ToppCell	BAL-Control-Epithelial-Epithelial-Basal/Club\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PITX1 MUC5B SLC5A8 MUC22 MUC4	2.12e-05	181	82	5	faff2a34e391d053a17c926540e6cb46d94dd629
ToppCell	BAL-Control-Epithelial-Epithelial-Basal/Club-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PITX1 MUC5B SLC5A8 MUC22 MUC4	2.12e-05	181	82	5	5a9c332c0bf07cc20eaf8cf77b45e73668a6467d
ToppCell	BAL-Control-Epithelial-Epithelial-Basal/Club-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PITX1 MUC5B SLC5A8 MUC22 MUC4	2.12e-05	181	82	5	488a517f6e5543b648a2e72e0e04332fad776de6
ToppCell	BAL-Control-Epithelial-Epithelial-Basal/Club\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	PITX1 MUC5B SLC5A8 MUC22 MUC4	2.12e-05	181	82	5	58651853f9c715075889856793df66ebe00c04f1
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NRXN3 MUC16 MUC5B MUC4 WNK2	2.17e-05	182	82	5	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	Epithelial-lung_goblet_cell\|World / Lineage, Cell type, age group and donor	NRXN3 MUC16 MUC5B MUC4 WNK2	2.23e-05	183	82	5	940cbe298e9c53b5622af09264586ed823d3141f
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX6 ARHGAP32 NRXN3 MTCL1 LRBA	2.35e-05	185	82	5	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	COPD-Epithelial-Goblet\|World / Disease state, Lineage and Cell class	FOXP2 MUC16 MUC5B MUC4 WNK2	2.41e-05	186	82	5	d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 MUC5B SLC5A8 MUC4 WNK2	2.54e-05	188	82	5	5901b276f2379abf486b8285957277e95f08464e
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SOX6 NCOA2 SEMA6D FOXP2 LRBA	2.60e-05	189	82	5	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP32 MUC16 SLC5A8 MUC4 FOXG1	2.67e-05	190	82	5	6ea9fa08bd97bedcb21d3654467e7f8dd74c8fd0
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PCNX2 NRXN3 CAMK2B CBARP AMER3	2.67e-05	190	82	5	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	cellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 MUC5B SLC5A8 MUC4 WNK2	2.74e-05	191	82	5	30e7cc5f7eadf90ab0900a73fdfe48f9a1adcbfb
ToppCell	cellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct-SMG_Basal/Duct\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 MUC5B SLC5A8 MUC4 WNK2	2.74e-05	191	82	5	41d2f5278f6d5f52a5bdf4f3df70969481c00162
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	NRXN3 FOXP2 PRKCI ADGRF5 SLC5A8	2.81e-05	192	82	5	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	COPD-Epithelial-Goblet\|COPD / Disease state, Lineage and Cell class	FOXP2 MUC16 MUC5B MUC4 WNK2	2.81e-05	192	82	5	93b2ca0a97776d28c7e8f1a0642c4b63a5554aab
ToppCell	cellseq-Epithelial-Epithelial_Glandular-Goblet\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 MUC5B SLC5A8 MUC4 WNK2	2.88e-05	193	82	5	71bf8fb5314b79cb30f4eb9c8459b21f10cd6d35
ToppCell	21-Trachea-Epithelial-Epithelial\|Trachea / Age, Tissue, Lineage and Cell class	ANK2 NRXN1 NRXN2 MUC17 FOXG1	2.88e-05	193	82	5	9a8bb44a37f3202e3123a6680bd5545dc91a6d40
ToppCell	cellseq-Epithelial-Epithelial_Glandular-Goblet-Goblet\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 MUC5B SLC5A8 MUC4 WNK2	2.88e-05	193	82	5	b05e110b13d35d34294357c8e1c4fd23bf4b6c92
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TEAD2 SEMA6D NRXN1 PITX1 RNF157	2.95e-05	194	82	5	68d15917ae222cba0ad9e716d29eebb6c5f00f69
ToppCell	cellseq-Epithelial-Epithelial_Glandular\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 MUC5B SLC5A8 MUC4 WNK2	2.95e-05	194	82	5	d0fb1ff5cf0738881e114a58f0b27489f781d72b
ToppCell	Bronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 MUC16 MUC5B SLC5A8 WNK2	3.02e-05	195	82	5	fc2a1d84b3d013e5cb9e7b9cdd740e4010897d20
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP32 HIVEP2 NRXN1 FOXP2 CAMK2B	3.02e-05	195	82	5	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	15-Trachea-Epithelial-Epithelial\|Trachea / Age, Tissue, Lineage and Cell class	ANK2 NRXN1 NRXN2 PITX2 FOXG1	3.02e-05	195	82	5	9e9283a397f56732a0a5f2e2527f154d4c2dd56a
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	NCOA2 FOXP2 LRRC37A3 LRBA TMCC1	3.10e-05	196	82	5	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 MUC5B SLC5A8 MUC4 WNK2	3.10e-05	196	82	5	c18874f37b90e6afacc562b2082b67ea8a7cb4a4
ToppCell	COVID-19-Epithelial-Club,_Basal_cells\|COVID-19 / Condition, Lineage and Cell class	MUC16 MUC5B SLC5A8 MUC4 WNK2	3.10e-05	196	82	5	dd32046067d93b9484cfbf1d7826a436a3d9f0e9
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PITX1 MUC16 MUC5B SLC5A8 MUC4	3.10e-05	196	82	5	a52879a4c822c5e4be569f01f845a795e00c5f4b
ToppCell	BAL-Mild-Epithelial-Epithelial-Basal/Club-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MUC16 MUC5B SLC5A8 MUC4 WNK2	3.10e-05	196	82	5	a4d05d85fbafa869df19bba3881020ea433d81fb
ToppCell	Bronchial-NucSeq-Stromal-Schwann\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NRXN3 ANK2 NRXN1 OR1L6 CBARP	3.10e-05	196	82	5	a90c76d9c57a4491b94a321ba541b792ec5d8e83
ToppCell	BAL-Mild-Epithelial-Epithelial-Basal/Club-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MUC16 MUC5B SLC5A8 MUC4 WNK2	3.10e-05	196	82	5	91a3c3091064f1f5a3bdc1dd5883fc24dce8ff05
ToppCell	BAL-Mild-Epithelial-Epithelial-Basal/Club\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MUC16 MUC5B SLC5A8 MUC4 WNK2	3.10e-05	196	82	5	e819088a74d29e958371aa851ac9c74ec55367b7
ToppCell	BAL-Mild-Epithelial-Epithelial-Basal/Club\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MUC16 MUC5B SLC5A8 MUC4 WNK2	3.10e-05	196	82	5	e675d661b6494ac3a85ba7ee5bdeaa98b8bbe957
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PITX1 MUC16 MUC5B SLC5A8 MUC4	3.10e-05	196	82	5	7a4d502550e9e37dc42f2ff1be3c896afe365d7f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PITX1 MUC16 MUC5B SLC5A8 MUC4	3.10e-05	196	82	5	60ea673ed887fe3890c5cf4ff4165384b76d7361
ToppCell	distal-Epithelial-Goblet\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PITX1 MUC16 MUC5B MUC4 WNK2	3.18e-05	197	82	5	da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCell	AT2_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	ADGRF5 MUC5B SLC5A8 MUC3A MUC4	3.18e-05	197	82	5	5e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCell	distal-3-Epithelial-Goblet\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PITX1 MUC16 MUC5B MUC4 WNK2	3.18e-05	197	82	5	a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCell	Bronchial-NucSeq-Stromal-Schwann-Schwann_nonmyelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NRXN3 ANK2 NRXN1 OR1L6 CBARP	3.18e-05	197	82	5	4a7ff67bb0754e034e6f2a1bd34cde86ee3ef899
ToppCell	Bronchus_Control_(B.)\|World / Sample group, Lineage and Cell type	HIVEP2 PITX1 MUC16 MUC5B MUC4	3.18e-05	197	82	5	b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCell	Mild_COVID-19-Epithelial-Basal/Club\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	MUC16 MUC5B SLC5A8 MUC4 WNK2	3.18e-05	197	82	5	4cc5b778e1e2c6c149160fa147c172977c0fa8eb
ToppCell	distal-Epithelial-Goblet-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PITX1 MUC16 MUC5B MUC4 WNK2	3.18e-05	197	82	5	3fbf456ae4f73da4f6254a6f0d24f0ec27d7a3cc
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_basal-Suprabasal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MCIDAS PITX1 MUC16 MUC5B MUC4	3.25e-05	198	82	5	de5987588b9fa9ee8c595ba06d7d844ead0e3c74
ToppCell	NS-critical-d_07-13\|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARHGAP32 PITX1 MUC16 SLC5A8 MUC4	3.25e-05	198	82	5	a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M\|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.	SOX6 SEMA6D NRXN1 TMEM123 FOXG1	3.33e-05	199	82	5	b2d7dea11207cca63d688f8051143850b29dbdf0
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MUC16 MUC5B SLC5A8 MUC4 WNK2	3.33e-05	199	82	5	ec1e110671e7725f752163c7241dbbf638dec2b2
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	NCOA2 ARHGAP32 FOXP2 LRRC37A3 LRBA	3.33e-05	199	82	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Striatum-Neuronal\|Striatum / BrainAtlas - Mouse McCarroll V32	PCNX2 NRXN3 CAMK2B CBARP AMER3	3.41e-05	200	82	5	c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 FOXP2 MUC16 MUC5B WNK2	3.41e-05	200	82	5	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Club\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	MUC16 MUC5B SLC5A8 MUC4 WNK2	3.41e-05	200	82	5	292c63693eb7f435335a8cfba07aa35b72139393
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 FOXP2 MUC16 MUC5B WNK2	3.41e-05	200	82	5	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	Biopsy_Control_(H.)-Epithelial-Differentiating_Ciliated\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	MCIDAS PITX1 MUC5B MUC4 WNK2	3.41e-05	200	82	5	a552a99f5e4fa00dfb7775e5a3e1f62f1530d104
Drug	Clozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A	PCNX2 NCOA2 SEMA6D HUWE1 SLC24A1 HCFC1 FOXG1	5.69e-06	195	80	7	5265_UP
Drug	Phenethicillin potassium salt [132-93-4]; Up 200; 10uM; PC3; HT_HG-U133A	NRXN2 SPN CAMK2B SLC24A1 MUC4 FOXG1 IMPG2	6.28e-06	198	80	7	5763_UP
Drug	cellobiitol	MUC3B SPN MUC3A MUC4	8.54e-06	37	80	4	CID000003871
Disease	Autistic Disorder	PDE4A NRXN3 NRXN1 FOXP2 NRXN2 PITX1 ROBO1 TNFRSF1B	4.18e-07	261	77	8	C0004352
Disease	cholangiocarcinoma (is_marker_for)	MUC16 MUC5B MUC3A MUC4	2.42e-05	64	77	4	DOID:4947 (is_marker_for)
Disease	autism spectrum disorder (implicated_via_orthology)	ARHGAP32 NRXN3 NRXN1 NRXN2 LRBA	4.98e-05	152	77	5	DOID:0060041 (implicated_via_orthology)
Disease	transient cerebral ischemia (biomarker_via_orthology)	ANK2 NRXN1 ROBO1 WNK2 HTT	5.80e-05	157	77	5	DOID:224 (biomarker_via_orthology)
Disease	polycystic ovary syndrome (implicated_via_orthology)	NCOA2 NCOR1	1.00e-04	6	77	2	DOID:11612 (implicated_via_orthology)
Disease	age at diagnosis, substance-related disorder	SEMA6D FOXP2	1.00e-04	6	77	2	EFO_0004918, MONDO_0002494
Disease	Intellectual Disability	HIVEP2 NRXN1 NRXN2 CAMK2B PACS2 FOXG1 HTT	1.69e-04	447	77	7	C3714756
Disease	underweight body mass index status	NRXN3 ANK2	2.39e-04	9	77	2	EFO_0005936
Disease	otitis media (is_marker_for)	MUC5B MUC4	2.98e-04	10	77	2	DOID:10754 (is_marker_for)
Disease	cognitive inhibition measurement	HIVEP2 SEMA6D MUC22	3.07e-04	50	77	3	EFO_0007969
Disease	polymyositis (is_marker_for)	ROBO1 TNFRSF1B	3.64e-04	11	77	2	DOID:0080745 (is_marker_for)
Disease	Semantic-Pragmatic Disorder	NRXN1 FOXP2	3.64e-04	11	77	2	C0454655
Disease	Auditory Processing Disorder, Central	NRXN1 FOXP2	3.64e-04	11	77	2	C0751257
Disease	Language Delay	NRXN1 FOXP2	3.64e-04	11	77	2	C0023012
Disease	Language Development Disorders	NRXN1 FOXP2	3.64e-04	11	77	2	C0023014
Disease	Speech Delay	NRXN1 FOXP2	3.64e-04	11	77	2	C0241210
Disease	outer ear morphology trait	HIVEP2 LRBA	4.36e-04	12	77	2	EFO_0007664
Disease	Alzheimer's disease (implicated_via_orthology)	SOX6 HIVEP2 ANK2	4.52e-04	57	77	3	DOID:10652 (implicated_via_orthology)
Disease	systolic blood pressure, cigarettes per day measurement	NRXN3 FOXP2	5.15e-04	13	77	2	EFO_0006335, EFO_0006525
Disease	Mental Depression	PDE4A NRXN1 PRKCI TNFRSF1B HTT	5.42e-04	254	77	5	C0011570
Disease	pancreatic ductal carcinoma (is_marker_for)	MUC5B MUC3A MUC4	5.51e-04	61	77	3	DOID:3587 (is_marker_for)
Disease	sulfate measurement	FOXP2 HTT	5.99e-04	14	77	2	EFO_0007864
Disease	Ischemic stroke, tissue plasminogen activator measurement	PITX2 HECTD4	6.90e-04	15	77	2	EFO_0004791, HP_0002140
Disease	Ischemic stroke, plasminogen activator inhibitor 1 measurement	PITX2 HECTD4	7.88e-04	16	77	2	EFO_0004792, HP_0002140
Disease	1-Methylhistidine measurement	NCOA2 ALMS1	8.91e-04	17	77	2	EFO_0021543
Disease	factor XI measurement, Ischemic stroke	PITX2 HECTD4	8.91e-04	17	77	2	EFO_0004694, HP_0002140
Disease	Depressive disorder	PDE4A NRXN1 PRKCI TNFRSF1B HTT	9.68e-04	289	77	5	C0011581
Disease	attention deficit hyperactivity disorder, Cannabis use	SEMA6D FOXP2	1.00e-03	18	77	2	EFO_0003888, EFO_0007585
Disease	factor VIII measurement, Ischemic stroke	PITX2 HECTD4	1.12e-03	19	77	2	EFO_0004630, HP_0002140
Disease	post-traumatic stress disorder symptom measurement	SOX6 FOXP2 LRRC37A2	1.30e-03	82	77	3	EFO_0008535
Disease	hair color	SOX6 SP2 SEMA6D HECTD4 CHMP1A	1.34e-03	311	77	5	EFO_0003924
Disease	Autism Spectrum Disorders	NRXN3 NRXN1 NRXN2	1.45e-03	85	77	3	C1510586
Disease	smoking cessation	SOX6 NRXN3 SEMA6D ALMS1 NRXN1	1.62e-03	325	77	5	EFO_0004319
Disease	frailty measurement	FOXP2 HTT	1.64e-03	23	77	2	EFO_0009885
Disease	reaction time measurement	SOX6 SEMA6D NRXN1 FOXP2 PITX2 LRRC37A2 HECTD4	1.66e-03	658	77	7	EFO_0008393
Disease	Malignant neoplasm of breast	NCOA2 NCOR1 LRRC37A ANK2 LRRC37A2 ROBO1 ZNF318 LRBA TP53BP1	1.90e-03	1074	77	9	C0006142
Disease	chronotype measurement	SOX6 NRXN3 SEMA6D ANK2 NRXN1 FOXP2 ZNF318 TMEM123	2.11e-03	882	77	8	EFO_0008328
Disease	Schizophrenia	ARHGAP32 PDE4A NRXN3 NRXN1 FOXP2 NRXN2 CAMK2B TNFRSF1B	2.12e-03	883	77	8	C0036341
Disease	caudate volume change measurement, age at assessment	NRXN3 NRXN1	2.26e-03	27	77	2	EFO_0008007, EFO_0021491
Disease	colorectal adenocarcinoma (is_marker_for)	NCOA2 RICTOR	2.26e-03	27	77	2	DOID:0050861 (is_marker_for)
Disease	Disorder of eye	ALMS1 PITX2 SLC24A1 IMPG2	2.33e-03	212	77	4	C0015397
Disease	1,5 anhydroglucitol measurement	PCDHAC1 MGAM2	2.61e-03	29	77	2	EFO_0008009
Disease	Ischemic stroke, factor VII measurement	PITX2 HECTD4	2.61e-03	29	77	2	EFO_0004619, HP_0002140

Protein segments in the cluster

Peptide	Gene	Start	Entry
MLEQKQSSSSPSMTT	AMER3	716	Q8N944
MQPTATMATAATTTT	CBARP	1	Q8N350
TPRTTMTMQTSTLDV	ADGRG4	1596	Q8IZF6
MRSHTITMTTTSVSS	GPR34	1	Q9UPC5
PMMTVIKSDSSSDAS	ALMS1	2406	Q8TCU4
IAGLMSMSTSTTSAV	CCNT1	296	O60563
TWTVPAQTTTPMSTM	MUC5B	4761	Q9HC84
AQTTTPMSTMSTIHT	MUC5B	4766	Q9HC84
TTMATMPTATASTVP	MUC5B	4881	Q9HC84
LTTSVTMTTDTMTSP	MTCL1	1476	Q9Y4B5
MQSDSVSSSFEPTMS	ANK2	3006	Q01484
TSVMEDSMSSATTLT	CHMP1A	126	Q9HD42
QMEDTMSSTTTLTTP	CHMP1B	131	Q7LBR1
ENSMSVPSSTSTMKT	PAPOLB	531	Q9NRJ5
TSATSTTMTVMATGA	HCFC1	1171	P51610
VMVSKFTSPATSSME	MUC16	996	Q8WXI7
FTMAKESVSMSVSPS	MUC16	1071	Q8WXI7
ESVSMSVSPSQSMDA	MUC16	1076	Q8WXI7
PMTISTHMTTTQTGS	MUC16	4671	Q8WXI7
ETSSVSSLMSSPAMT	MUC16	5331	Q8WXI7
SMMEDAIVSTSTPGS	MUC16	6046	Q8WXI7
PMDTTSTMGHTTVST	MUC16	6916	Q8WXI7
STMGHTTVSTSMSVS	MUC16	6921	Q8WXI7
TMTESAEMTIPTQTG	MUC16	7021	Q8WXI7
FSTSPVMTESAEITM	MUC16	7891	Q8WXI7
SKVTSPMVITSTMED	MUC16	8081	Q8WXI7
PMVITSTMEDTSVST	MUC16	8086	Q8WXI7
PAQSTMSSDTSMETI	MUC16	9336	Q8WXI7
TSSSIRDNMVSTTMP	MUC16	9551	Q8WXI7
VPTSATTEVSMTEIM	MUC16	9901	Q8WXI7
DTLTQMMTSTLFSSP	MUC4	91	Q99102
TSFPSSVTNTLMMTS	MUC4	121	Q99102
PSSMTTESTATAMQS	NRXN1	296	P58400
TESTATAMQSEMSTS	NRXN1	301	P58400
TAMQSEMSTSIMETT	NRXN1	306	P58400
SMTEVEPSTALMTTA	LRRC37A3	676	O60309
MPTQRDSSTMSHTVA	PRKCI	1	P41743
TAMASASPSVMSTNF	MAGEC3	626	Q8TD91
SMTEVEPSTALMTTA	LRRC37A2	676	A6NM11
SMTEVEPSTALMTTA	LRRC37A	676	A6NMS7
STSGMVEASQMPTVI	LRIF1	216	Q5T3J3
VPSTFMTMETSHAIT	SLC24A1	201	O60721
MTTSFSESTNAMNTT	MGAM2	2201	Q2M2H8
SESTNAMNTTVIMAT	MGAM2	2206	Q2M2H8
AMNTTVIMATTSPTS	MGAM2	2211	Q2M2H8
VKLSTMMSPTTSTNA	SPN	226	P16150
SITGSETTMASTMAS	MUC22	41	E2RYF6
ETTMASTMASTSALT	MUC22	46	E2RYF6
TMASSIISETTMAST	MUC22	166	E2RYF6
TTMVSAMGSETTTNS	MUC22	366	E2RYF6
TMASTMGSETTMAST	MUC22	546	E2RYF6
TASTTSSETTMASIM	MUC22	1016	E2RYF6
SSETTMASIMGSETT	MUC22	1021	E2RYF6
TSVTTSPQSDMMREQ	MCM3AP	1921	O60318
MGTTSDEMVSVEQTS	LNX2	1	Q8N448
VPHPSMTSQSSTSMS	FOXG1	421	P55316
IVITMSSTPNSMTDL	PCNX2	376	A6NKB5
MTETSLSSQCFPMSV	OR51F2	1	Q8NH61
TDVSLSMSTLPSMLS	OR51H1	71	Q8NH63
MTTTEKGTSAMTSSP	MUC3A	176	Q02505
GTMVTSTTMTPSSLS	MUC3A	426	Q02505
PTTDMSTESLTTAMT	MUC3A	616	Q02505
VPTTLGTMVTSTSMI	MUC3A	796	Q02505
GTMVTSTSMISSTVS	MUC3A	801	Q02505
SPTTTTSFTTSTMME	MUC3A	946	Q02505
TSFTTSTMMEPPSST	MUC3A	951	Q02505
SSSITPTNTMTSMRT	MUC3A	1011	Q02505
TSGTMVTSTTMTPSS	MUC3A	1176	Q02505
PITSSITPTDTMTSM	MUC3A	1386	Q02505
ITPTDTMTSMRTTTS	MUC3A	1391	Q02505
TMTSMRTTTSWPTAT	MUC3A	1396	Q02505
TTLGTMVTSTSMIPS	MUC3A	1551	Q02505
MVTSTSMIPSTVSTG	MUC3A	1556	Q02505
NTETSIFVSMMSATT	MUC3A	1621	Q02505
TTTMSFTTFTKMETP	MUC3A	1701	Q02505
TSSMMPESESSISPN	MUC3A	2831	Q02505
MSPKTMSRNSSVTSE	PDE4A	156	P27815
VSSVTMSKNMLETSP	FOXP2	426	O15409
MATTIMETTTTMATT	NRXN2	1361	Q9P2S2
GTTQTTSMPPEMSTT	NRXN3	1271	Q9Y4C0
EMSTTVMETTTTMAT	NRXN3	1281	Q9Y4C0
TMTASGSSAMSPETT	LRBA	1181	P50851
HSVASMMAVNSSSPT	MIGA2	136	Q7L4E1
PSSMTTESTATAMQS	NRXN1	1301	Q9ULB1
TESTATAMQSEMSTS	NRXN1	1306	Q9ULB1
TAMQSEMSTSIMETT	NRXN1	1311	Q9ULB1
SGEAAATPTMSMTVV	PACS2	791	Q86VP3
SMEVSTSSSLTPAMS	HECTD4	3046	Q9Y4D8
SPEENTSTATMTYMT	ARHGAP32	1251	A7KAX9
QLPSMSMLTSKTSTQ	HUWE1	3706	Q7Z6Z7
TTMDTDCGSMSTVVS	RICTOR	1246	Q6R327
TVDDLISDSSSMMSP	MCIDAS	121	D6RGH6
TTEIPTTMSTMAAAE	PRPF40A	261	O75400
MVSNPCMTSATIDVT	PCDHAC1	731	Q9H158
NTTTPGMVSTNMTST	TMEM123	96	Q8N131
GMVSTNMTSTTLKST	TMEM123	101	Q8N131
MFVTPNTMASVSTVQ	HTT	1656	P42858
GMASASTTMHTTTIA	GYPC	21	P04921
STVTATTATTTLMMT	DEFB126	81	Q9BYW3
TTATTTLMMTTASMS	DEFB126	86	Q9BYW3
SDTSSSQMVVMTETL	OR1L4	191	Q8NGR5
CSDTSSSQMVVMTET	OR1L6	226	Q8NGR2
ASTMPVATSEMSTLS	MUC17	341	Q685J3
MSVSTMPVASSEAST	MUC17	516	Q685J3
RMPVSTTMVASSETS	MUC17	1046	Q685J3
SMSVSTMPVASSEAS	MUC17	2991	Q685J3
SSPATLQVTTMRMST	MUC17	3556	Q685J3
MRMSTPSEGSSSLTT	MUC17	3566	Q685J3
ATLDSTTMSVSMPME	MUC17	3736	Q685J3
TTLEGTTTMPMSTTS	MUC17	3796	Q685J3
TTTMPMSTTSERSTL	MUC17	3801	Q685J3
MTTTEKGTSAMISSP	MUC3B	176	Q9H195
MVTCPSSISMQTTLA	MUC3B	726	Q9H195
QTTLATHMDTSSMTP	MUC3B	736	Q9H195
THMDTSSMTPESESS	MUC3B	741	Q9H195
TSTQLMTSPVFDTMS	RTL9	61	Q8NET4
VVCTPIMSTSSSEAM	RTL9	176	Q8NET4
IMSTSSSEAMSTPLM	RTL9	181	Q8NET4
SSGVMSTEQMSATAS	RTL9	446	Q8NET4
STQPVTATASETMSM	RTL9	511	Q8NET4
TATASETMSMPQLTV	RTL9	516	Q8NET4
QSMFSAPSSISSMTM	PITX1	211	P78337
TAPATMSTAASGTTM	CAMK2B	321	Q13554
AQSVMSMASSQISTD	RNF157	516	Q96PX1
SMASSQISTDTVSSM	RNF157	521	Q96PX1
GTTQTTSMPPEMSTT	NRXN3	266	Q9HDB5
EMSTTVMETTTTMAT	NRXN3	276	Q9HDB5
MLTITSIFSSSNMTV	OVCH1	496	Q7RTY7
SPMMNRTSDVTISSN	NCOR1	1496	O75376
ETNLMTTTEMPFTTS	SLC5A8	486	Q8N695
TMATMSSAQLISAPS	TEAD2	131	Q15562
SISSMSMSSSMVPSA	PITX2	216	Q99697
SSGQKITHVVSSTMM	SHCBP1	326	Q8NEM2
VEMSTSVHSTEMVSV	IMPG2	866	Q9BZV3
AITMATTTPSPQMTS	SOX6	746	P35712
SLVMTTTVSHNTTMP	ADGRF5	921	Q8IZF2
ASSMTAASSTPMTLA	C11orf24	151	Q96F05
QMTGQISMTSVTSVP	NCOA2	1406	Q15596
MTSQSSVISNSCVTM	ZNF568	1	Q3ZCX4
MSDPQTSMAATAAVS	SP2	1	Q02086
ITMMTTQTSTMTFAP	TMEM38B	221	Q9NVV0
SSSTTDAPTSSAMME	TMCC1	156	O94876
TSPVSTDSNMSAAVM	ROBO1	1441	Q9Y6N7
PESTIATSDVMSESM	TP53BP1	946	Q12888
MDAVCTSTSPTRSMA	TNFRSF1B	196	P20333
AVMEQGTSSSMTAES	WNK2	1671	Q9Y3S1
IDETASDMSMSPQSS	HIVEP2	1571	P31629
PTSDMEVSSSSVTTM	SEMA6D	586	Q8NFY4
MEPSMQLESFSSSTS	ZNF318	391	Q5VUA4
LEQTVSMATTTQPMT	THAP4	551	Q8WY91
ASDITSTSMSMPEHV	ZFY	121	P08048
STSMSMPEHVLTSES	ZFY	126	P08048