Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	WW domain binding	TREX1 WBP11 DNM2	1.24e-04	25	78	3	GO:0050699
GeneOntologyBiologicalProcess	vesicle cargo loading	MIA3 CTAGE8 CTAGE15 CTAGE6	1.12e-05	36	80	4	GO:0035459
GeneOntologyCellularComponent	endoplasmic reticulum exit site	MIA3 CTAGE8 SEC16A CTAGE15 CTAGE6	5.51e-07	42	80	5	GO:0070971
GeneOntologyCellularComponent	nuclear body	WBP11 RBM25 SETD1B NFATC4 RBBP6 CPSF6 YLPM1 DVL2 RERE MAPK7 SKI SF3A2	1.58e-04	903	80	12	GO:0016604
GeneOntologyCellularComponent	nuclear speck	WBP11 RBM25 SETD1B NFATC4 RBBP6 CPSF6 YLPM1 SF3A2	2.43e-04	431	80	8	GO:0016607
GeneOntologyCellularComponent	nuclear protein-containing complex	DCAF1 MLXIPL RBM22 SETD1B CPSF6 BICRA MED25 RERE KDM6B PDCD7 POLR1G MIDEAS UVRAG SF3A2	6.77e-04	1377	80	14	GO:0140513
HumanPheno	High hypermetropia	MED25 RERE SKI RAX RAI1	5.84e-05	82	27	5	HP:0008499
HumanPheno	Self-injurious behavior	TREX1 MAGEL2 RERE SKI WASF1 RAI1 SCAF4	8.04e-05	210	27	7	HP:0100716
HumanPheno	Hypermetropia	MAGEL2 SOBP BICRA MED25 RERE SKI RAX RAI1	8.18e-05	288	27	8	HP:0000540
HumanPheno	Disinhibition	MLXIPL TREX1 WBP11 MAGEL2 AGO2 MED25 TOMM40 RERE KDM6B SKI WASF1 RAI1 SCAF4	8.25e-05	807	27	13	HP:0000734
HumanPheno	Inappropriate behavior	MLXIPL TREX1 WBP11 MAGEL2 AGO2 MED25 TOMM40 RERE KDM6B SKI WASF1 RAI1 SCAF4	8.25e-05	807	27	13	HP:0000719
HumanPheno	Abnormal response to social norms	MLXIPL TREX1 WBP11 MAGEL2 AGO2 MED25 TOMM40 RERE KDM6B SKI WASF1 RAI1 SCAF4	8.25e-05	807	27	13	HP:5200123
HumanPheno	Social disinhibition	MLXIPL TREX1 WBP11 MAGEL2 AGO2 MED25 TOMM40 RERE KDM6B SKI WASF1 RAI1 SCAF4	8.25e-05	807	27	13	HP:5200029
HumanPheno	Impairment in personality functioning	MLXIPL TREX1 WBP11 MAGEL2 AGO2 SETD1B ANXA11 MED25 TOMM40 RERE KDM6B SKI WASF1 RAI1 SCAF4	1.80e-04	1141	27	15	HP:0031466
HumanPheno	Abnormally increased volition	MLXIPL TREX1 WBP11 MAGEL2 AGO2 MED25 TOMM40 RERE KDM6B SKI WASF1 RAI1 SCAF4	1.81e-04	869	27	13	HP:5200263
HumanPheno	Recurrent maladaptive behavior	MLXIPL TREX1 WBP11 MAGEL2 AGO2 SETD1B BICRA ANXA11 MED25 TOMM40 RERE KDM6B SKI WASF1 RAI1 SCAF4	1.88e-04	1293	27	16	HP:5200241
HumanPheno	Strabismus	MLXIPL TREX1 MAGEL2 FBN1 AGO2 SOBP BICRA MED25 RERE KDM6B SKI WASF1 RAX RAI1 SCAF4	2.17e-04	1159	27	15	HP:0000486
HumanPheno	Language impairment	TREX1 MAGEL2 AGO2 SETD1B SOBP ANXA11 MED25 FMN2 TOMM40 RERE KDM6B SKI WASF1 RAI1 SCAF4	2.63e-04	1178	27	15	HP:0002463
HumanPheno	Abnormal social development	MLXIPL TREX1 WBP11 MAGEL2 AGO2 MED25 TOMM40 RERE KDM6B SKI WASF1 RAI1 SCAF4	2.86e-04	908	27	13	HP:0025732
HumanPheno	Abnormal conjugate eye movement	MLXIPL TREX1 MAGEL2 FBN1 AGO2 SOBP BICRA MED25 RERE KDM6B SKI WASF1 RAX RAI1 SCAF4	3.21e-04	1198	27	15	HP:0000549
HumanPheno	Bicuspid aortic valve	MLXIPL FBN1 AGO2 RAI1 SCAF4	3.42e-04	119	27	5	HP:0001647
HumanPheno	Deeply set eye	FBN1 AGO2 BICRA RERE SKI WASF1 RAI1	3.52e-04	266	27	7	HP:0000490
HumanPheno	Chronic constipation	MLXIPL MAGEL2 BICRA WASF1 RAI1	3.56e-04	120	27	5	HP:0012450
HumanPheno	Abnormal aortic valve cusp morphology	MLXIPL FBN1 AGO2 RAI1 SCAF4	3.70e-04	121	27	5	HP:0031567
MousePheno	decreased skeletal muscle fiber size	FOXN1 MAGEL2 SKI WASF1 DNM2	5.86e-05	97	60	5	MP:0009400
MousePheno	embryonic lethality prior to organogenesis	DCAF1 RBM22 WBP11 RBM25 FBN1 AGO2 WTIP RBBP6 CTAGE8 YLPM1 TOMM40 PDCD7 POLR1G RAI1 DNM2	1.27e-04	1204	60	15	MP:0013292
MousePheno	abnormal craniofacial morphology	TREX1 WBP11 MIA3 FBN1 DMRT3 RASA1 FAM120C GLG1 RERE MAPK7 SKI FOXI3 RAX SOCS7 RAI1 DNM2	1.56e-04	1372	60	16	MP:0000428
MousePheno	craniofacial phenotype	TREX1 WBP11 MIA3 FBN1 DMRT3 RASA1 FAM120C GLG1 RERE MAPK7 SKI FOXI3 RAX SOCS7 RAI1 DNM2	1.56e-04	1372	60	16	MP:0005382
MousePheno	embryonic lethality prior to tooth bud stage	DCAF1 RBM22 WBP11 RBM25 FBN1 AGO2 RASA1 WTIP RBBP6 CTAGE8 YLPM1 TOMM40 PDCD7 POLR1G RAI1 DNM2	1.71e-04	1383	60	16	MP:0013293
MousePheno	abnormal food intake	MLXIPL MAGEL2 FBN1 FGF21 HCN2 WASF1 SOCS7 RAI1 DNM2	1.95e-04	481	60	9	MP:0005449
MousePheno	abnormal cutaneous collagen fibril morphology	FOXN1 MIA3 FBN1	2.04e-04	27	60	3	MP:0008438
MousePheno	decreased skeletal muscle mass	FOXN1 MAGEL2 SKI WASF1 DNM2	2.42e-04	131	60	5	MP:0004819
MousePheno	abnormal skeletal muscle fiber morphology	FOXN1 MAGEL2 FBN1 SKI WASF1 DNM2	2.87e-04	212	60	6	MP:0003084
MousePheno	decreased food intake	MLXIPL MAGEL2 FBN1 HCN2 DNM2	2.98e-04	137	60	5	MP:0011940
MousePheno	abnormal muscle fiber morphology	FOXN1 TREX1 MAGEL2 FBN1 SKI WASF1 UVRAG DNM2	3.22e-04	406	60	8	MP:0004087
MousePheno	abnormal skeletal muscle fiber size	FOXN1 MAGEL2 SKI WASF1 DNM2	3.29e-04	140	60	5	MP:0009398
MousePheno	abnormal fetal growth/weight/body size	WBP11 MIA3 BICRA GLG1 KDM6B SKI MIDEAS	3.61e-04	312	60	7	MP:0004197
MousePheno	abnormal presacral vertebrae morphology	RBM22 WBP11 FBN1 DVL2 SKI RAI1	3.94e-04	225	60	6	MP:0000459
MousePheno	abnormal spine curvature	TREX1 MAGEL2 FBN1 DVL2 KDM6B SKI RAI1	4.05e-04	318	60	7	MP:0004174
MousePheno	decreased fetal size	WBP11 MIA3 BICRA GLG1 KDM6B SKI	4.33e-04	229	60	6	MP:0004200
MousePheno	abnormal skeletal muscle mass	FOXN1 MAGEL2 SKI WASF1 DNM2	4.38e-04	149	60	5	MP:0004817
MousePheno	double outlet right ventricle	BICRA DVL2 RERE MAPK7 DNM2	4.52e-04	150	60	5	MP:0000284
Domain	SMR-like	SMR3A SMR3B	4.76e-05	3	75	2	IPR026288
Domain	PROL5-SMR	SMR3A SMR3B	4.76e-05	3	75	2	PF15621
Domain	SANT_dom	DNAJC1 RERE MIDEAS	1.51e-04	26	75	3	IPR017884
Domain	-	RBM25 RBM26	1.58e-04	5	75	2	1.20.1390.10
Domain	PWI	RBM25 RBM26	1.58e-04	5	75	2	PF01480
Domain	PWI_dom	RBM25 RBM26	1.58e-04	5	75	2	IPR002483
Domain	RRM_1	RBM22 RBM25 SETD1B CPSF6 RBM26 SCAF4	1.89e-04	208	75	6	PF00076
Domain	SANT	DNAJC1 RERE MIDEAS	1.90e-04	28	75	3	PS51293
Domain	RRM	RBM22 RBM25 SETD1B CPSF6 RBM26 SCAF4	2.37e-04	217	75	6	SM00360
Domain	RRM_dom	RBM22 RBM25 SETD1B CPSF6 RBM26 SCAF4	3.02e-04	227	75	6	IPR000504
Domain	RRM	RBM22 RBM25 SETD1B CPSF6 RBM26 SCAF4	3.24e-04	230	75	6	PS50102
Domain	Myb_DNA-binding	DNAJC1 RERE MIDEAS	3.71e-04	35	75	3	PF00249
Domain	-	RBM22 RBM25 SETD1B CPSF6 RBM26 SCAF4	4.44e-04	244	75	6	3.30.70.330
Domain	MYB_LIKE	DNAJC1 RERE MIDEAS	4.74e-04	38	75	3	PS50090
Domain	Nucleotide-bd_a/b_plait	RBM22 RBM25 SETD1B CPSF6 RBM26 SCAF4	5.95e-04	258	75	6	IPR012677
Domain	TF_fork_head_CS_2	FOXN1 FOXD4L3 FOXI3	8.34e-04	46	75	3	IPR030456
Domain	TF_fork_head_CS_1	FOXN1 FOXD4L3 FOXI3	8.88e-04	47	75	3	IPR018122
Domain	ZnF_C3H1	RBM22 RBM26 ZC3H6	9.45e-04	48	75	3	SM00356
Domain	zf-CCCH	RBM22 RBM26 ZC3H6	1.00e-03	49	75	3	PF00642
Domain	FH	FOXN1 FOXD4L3 FOXI3	1.00e-03	49	75	3	SM00339
Domain	FORK_HEAD_1	FOXN1 FOXD4L3 FOXI3	1.00e-03	49	75	3	PS00657
Domain	FORK_HEAD_2	FOXN1 FOXD4L3 FOXI3	1.00e-03	49	75	3	PS00658
Domain	Fork_head_dom	FOXN1 FOXD4L3 FOXI3	1.00e-03	49	75	3	IPR001766
Domain	FORK_HEAD_3	FOXN1 FOXD4L3 FOXI3	1.00e-03	49	75	3	PS50039
Domain	Forkhead	FOXN1 FOXD4L3 FOXI3	1.00e-03	49	75	3	PF00250
Domain	SANT	DNAJC1 RERE MIDEAS	1.06e-03	50	75	3	SM00717
Domain	SANT/Myb	DNAJC1 RERE MIDEAS	1.19e-03	52	75	3	IPR001005
Domain	ELM2	RERE MIDEAS	1.21e-03	13	75	2	PF01448
Domain	ELM2	RERE MIDEAS	1.21e-03	13	75	2	PS51156
Domain	ELM2_dom	RERE MIDEAS	1.21e-03	13	75	2	IPR000949
Domain	ELM2	RERE MIDEAS	1.21e-03	13	75	2	SM01189
Domain	WH2	WIPF3 WASF1	1.40e-03	14	75	2	SM00246
Domain	Znf_CCCH	RBM22 RBM26 ZC3H6	1.64e-03	58	75	3	IPR000571
Domain	ZF_C3H1	RBM22 RBM26 ZC3H6	1.64e-03	58	75	3	PS50103
Domain	WH2	WIPF3 WASF1	1.84e-03	16	75	2	PF02205
Domain	WH2_dom	WIPF3 WASF1	3.18e-03	21	75	2	IPR003124
Domain	DEP_dom	DVL2 FMN2	3.81e-03	23	75	2	IPR000591
Domain	WH2	WIPF3 WASF1	4.15e-03	24	75	2	PS51082
Pubmed	Interaction network of human early embryonic transcription factors.	PRR12 SOBP BICRA FBRS SEC16A TPRX1 TPRX2 RERE SKI MIDEAS RAI1	5.33e-10	351	80	11	38297188
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	WBP11 RBM25 RBBP6 CPSF6 BICRA YLPM1 RBM26 SEC16A DVL2 PRRC2A SF3A2	2.04e-09	399	80	11	35987950
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	MIA3 CPSF6 YLPM1 FBRS DVL2 PDCD7 PRRC2A SF3A2 SCAF4	2.16e-09	220	80	9	24550385
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	PRR12 CPSF6 YLPM1 RBM26 FBRS RERE SKI MIDEAS RAI1	1.21e-08	268	80	9	33640491
Pubmed	Human transcription factor protein interaction networks.	PRR12 WBP11 RBM25 FBN1 AGO2 NFATC4 RBBP6 SOBP BICRA YLPM1 FBRS SEC16A RERE SKI MIDEAS PRRC2A SCAF4	2.15e-08	1429	80	17	35140242
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	RBM22 WBP11 RBM25 AGO2 RBBP6 FAM120C CPSF6 ANXA11 YLPM1 RBM26 PRRC2A SF3A2 SCAF4	3.87e-08	807	80	13	22681889
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DCAF1 RBM25 AGO2 RBBP6 FAM120C BICRA FBRS SEC16A DVL2 FMN2 RERE SKI POLR1G RAI1	2.37e-07	1116	80	14	31753913
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PRR12 RBM22 RBBP6 FAM120C CPSF6 GLG1 RBM26 MED25 TOMM40 DNAJC1 PDCD7 POLR1G PRRC2A SF3A2 SCAF4 SEMA4C	2.55e-07	1497	80	16	31527615
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	WBP11 RBM25 RBBP6 CPSF6 BICRA ANXA11 YLPM1 RBM26 SEC16A MIDEAS PRRC2A RAI1 SCAF4	2.65e-07	954	80	13	36373674
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	WBP11 MIA3 AGO2 WTIP FAM120C YLPM1 SEC16A DVL2 HCN2 WASF1 PRRC2A RAI1 DNM2	2.95e-07	963	80	13	28671696
Pubmed	Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain.	PRR12 MIA3 AGO2 RBBP6 TOMM40 WASF1	1.02e-06	143	80	6	32560809
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	PRR12 RBM22 CPSF6 YLPM1 FBRS SEC16A TOMM40 MIDEAS RAI1	1.10e-06	457	80	9	32344865
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXN1 MLXIPL TSC22D1 DMRT3 NFATC4 FOXD4L3 TPRX1 RERE SKI FOXI3 MIDEAS RAX	1.10e-06	908	80	12	19274049
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	GPALPP1 PRR12 RBM22 WBP11 CPSF6 BICRA RBM26 MIDEAS PRRC2A SF3A2 RAI1 DNM2 SCAF4	1.35e-06	1103	80	13	34189442
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PRR12 MLXIPL TREX1 RBM22 RBM25 RBBP6 YLPM1 DNAJC1 SKI POLR1G MIDEAS SF3A2 RAI1 SCAF4	1.38e-06	1294	80	14	30804502
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	PRR12 SOBP CPSF6 BICRA FBRS MIDEAS	1.45e-06	152	80	6	38360978
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	WBP11 CPSF6 YLPM1 SF3A2 DNM2 SCAF4	1.57e-06	154	80	6	16055720
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	WBP11 RBM25 RBBP6 CPSF6 YLPM1 WIPF3 FMN2 SF3A2 SCAF4	2.53e-06	506	80	9	30890647
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	RBM25 AGO2 RBBP6 YLPM1 RBM26 SEC16A MIDEAS PRRC2A SCAF4	4.89e-06	549	80	9	38280479
Pubmed	A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism.	MLXIPL FGF21	5.23e-06	2	80	2	28123933
Pubmed	IκBNS induces Muc5ac expression in epithelial cells and causes airway hyper-responsiveness in murine asthma models.	NFKBID MUC5AC	5.23e-06	2	80	2	27878831
Pubmed	Inhibition of Glycolysis in Pathogenic TH17 Cells through Targeting a miR -21-Peli1-c-Rel Pathway Prevents Autoimmunity.	RBM25 AGO2 SKI	6.42e-06	16	80	3	32414810
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	RBBP6 FAM120C CPSF6 YLPM1 RBM26 MIDEAS SF3A2	1.41e-05	341	80	7	32971831
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	WBP11 RBM25 AGO2 FAM120C CPSF6 YLPM1 RBM26 SEC16A PDCD7 MIDEAS MUC5AC PRRC2A SCAF4	1.42e-05	1371	80	13	36244648
Pubmed	HRD1-ERAD controls production of the hepatokine FGF21 through CREBH polyubiquitination.	FGF21 SYVN1	1.57e-05	3	80	2	30389664
Pubmed	Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation.	TPRX1 TPRX2	1.57e-05	3	80	2	36074823
Pubmed	miR-143 interferes with ERK5 signaling, and abrogates prostate cancer progression in mice.	FOXN1 MAPK7	1.57e-05	3	80	2	19855844
Pubmed	FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver.	MLXIPL FGF21	1.57e-05	3	80	2	26724858
Pubmed	Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase.	FGF21 KDM6B	1.57e-05	3	80	2	32042044
Pubmed	FGF21 promotes endothelial cell angiogenesis through a dynamin-2 and Rab5 dependent pathway.	FGF21 DNM2	1.57e-05	3	80	2	24848261
Pubmed	Interleukin-13-induced MUC5AC expression is regulated by a PI3K-NFAT3 pathway in mouse tracheal epithelial cells.	NFATC4 MUC5AC	1.57e-05	3	80	2	24583134
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	WBP11 RBM25 RBBP6 CPSF6 YLPM1 RBM26 SF3A2 DNM2 SCAF4	1.94e-05	653	80	9	33742100
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	RBM25 AGO2 RBBP6 YLPM1 SEC16A RERE MAPK7 MIDEAS PRRC2A	1.99e-05	655	80	9	35819319
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SETD1B RBBP6 CPSF6 RBM26 PDCD7 SCAF4	2.56e-05	251	80	6	31076518
Pubmed	Integration of protein kinases mTOR and extracellular signal-regulated kinase 5 in regulating nucleocytoplasmic localization of NFATc4.	NFATC4 MAPK7	3.13e-05	4	80	2	18347059
Pubmed	Characterization and target genes of nine human PRD-like homeobox domain genes expressed exclusively in early embryos.	TPRX1 TPRX2	3.13e-05	4	80	2	27412763
Pubmed	The role of Dicer protein partners in the processing of microRNA precursors.	AGO2 RBBP6	3.13e-05	4	80	2	22163034
Pubmed	Intratumoral TREX1 Induction Promotes Immune Evasion by Limiting Type I IFN.	FOXN1 TREX1	3.13e-05	4	80	2	38408184
Pubmed	GLTSCR1, ATM, PPP1R13L and CD3EAP Genetic Variants and Lung Cancer Risk in a Chinese Population.	BICRA POLR1G	3.13e-05	4	80	2	30128886
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	RBM22 WBP11 RBBP6 CPSF6 GLG1 YLPM1 SEC16A WASF1 PRRC2A SCAF4	5.03e-05	922	80	10	27609421
Pubmed	Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes.	SBK1 YLPM1 DNM2	5.03e-05	31	80	3	19041431
Pubmed	Characterization and expression pattern of the novel MIA homolog TANGO.	MIA3 CTAGE8	5.20e-05	5	80	2	15183315
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	GPALPP1 RBBP6 CPSF6 YLPM1 RBM26 SEC16A DVL2 PRRC2A DNM2 SCAF4	5.60e-05	934	80	10	33916271
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	GPALPP1 PRR12 WBP11 MIA3 RBBP6 BICRA FBRS	5.71e-05	425	80	7	24999758
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	PRR12 CPSF6 YLPM1 SEC16A RAI1	6.17e-05	180	80	5	35198878
Pubmed	Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.	RBM25 CPSF6 YLPM1 FBRS SEC16A	6.50e-05	182	80	5	32239614
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	PRR12 FBN1 RBBP6 CPSF6 SEC16A	6.84e-05	184	80	5	32908313
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RBM25 RBBP6 YLPM1 SEC16A RERE POLR1G PRRC2A DNM2 SCAF4	7.24e-05	774	80	9	15302935
Pubmed	TANGO1 recruits Sec16 to coordinately organize ER exit sites for efficient secretion.	MIA3 SEC16A	7.79e-05	6	80	2	28442536
Pubmed	Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study.	MIA3 FMN2	7.79e-05	6	80	2	19955471
Pubmed	Nuclear factor of activated T cells (NFAT) proteins repress canonical Wnt signaling via its interaction with Dishevelled (Dvl) protein and participate in regulating neural progenitor cell proliferation and differentiation.	NFATC4 DVL2	7.79e-05	6	80	2	21880741
Pubmed	PSMC3 promotes RNAi by maintaining AGO2 stability through USP14.	AGO2 RBBP6	7.79e-05	6	80	2	36528617
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	DCAF1 RBM22 WBP11 RBM25 CPSF6 YLPM1 RBM26 POLR1G MIDEAS SF3A2	8.99e-05	989	80	10	36424410
Pubmed	Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins.	AGO2 WTIP	1.09e-04	7	80	2	28683311
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	GPALPP1 PRR12 AGO2 SETD1B FAM120C FMN2 PRRC2A	1.14e-04	475	80	7	31040226
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	GPALPP1 MLXIPL SHROOM1 CPSF6 RBM26 FBRS SEC16A DVL2 MAPK7 UVRAG	1.33e-04	1038	80	10	26673895
Pubmed	Genetic analysis of coronary artery disease single-nucleotide polymorphisms in diabetic nephropathy.	MIA3 FMN2	1.45e-04	8	80	2	19336575
Pubmed	RBBP6 activates the pre-mRNA 3' end processing machinery in humans.	RBBP6 CPSF6	1.45e-04	8	80	2	35177536
Pubmed	Mesenchymal-stem-cell-induced immunoregulation involves FAS-ligand-/FAS-mediated T cell apoptosis.	FOXN1 FBN1	1.45e-04	8	80	2	22542159
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SBK1 COL23A1 TSC22D1 MIA3 AGO2 RASA1 FAM120C SOBP BICRA RERE SKI RAI1	1.48e-04	1489	80	12	28611215
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	RBM22 RBM25 AGO2 SETD1B RBM26 SCAF4	1.53e-04	347	80	6	16033648
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXN1 RBM22 NFATC4 RBM26 DVL2 CHSY3 TOMM40 SKI WASF1	1.56e-04	857	80	9	25609649
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	RIN1 RBM25 RBBP6 RBM26 SEC16A POLR1G PRRC2A	1.62e-04	503	80	7	16964243
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	TSC22D1 MIA3 FBN1 YLPM1	1.63e-04	118	80	4	21078624
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	WBP11 RBM25 AGO2 RBBP6 CPSF6 SEC16A POLR1G PRRC2A	1.69e-04	678	80	8	30209976
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	RBM22 WBP11 FBN1 YLPM1 NFKBID FMN2 KDM6B PDCD7 PRRC2A SF3A2 DNM2	1.70e-04	1285	80	11	35914814
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	DCAF1 MIA3 SEC16A PRRC2A DNM2 SCAF4	1.86e-04	360	80	6	33111431
Pubmed	Formin 2 Regulates Lysosomal Degradation of Wnt-Associated β-Catenin in Neural Progenitors.	DVL2 FMN2	1.86e-04	9	80	2	29659741
Pubmed	LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing.	AGO2 WTIP	1.86e-04	9	80	2	20616046
Pubmed	The E3 ubiquitin ligase Cul4b promotes CD4+ T cell expansion by aiding the repair of damaged DNA.	DCAF1 RBBP6	1.86e-04	9	80	2	33524014
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RBM22 WBP11 RBM25 RBBP6 CPSF6 YLPM1 PDCD7 ZC3H6 SF3A2 SCAF4	1.87e-04	1082	80	10	38697112
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	GPALPP1 RBM22 RBM25 RBBP6 CPSF6 SEC16A DVL2 TOMM40 POLR1G SF3A2 DNM2	2.12e-04	1318	80	11	30463901
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PRR12 SETD1B BICRA ANXA11 FBRS SEC16A SYVN1 KDM6B UVRAG RAI1	2.21e-04	1105	80	10	35748872
Pubmed	A novel pro-Arg motif recognized by WW domains.	WBP11 PRRC2A	2.32e-04	10	80	2	10744724
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	GPALPP1 RBM22 RBM25 RBM26	2.37e-04	130	80	4	35545047
Pubmed	Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.	RASA1 SOCS7	2.84e-04	11	80	2	20598684
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	DCAF1 WBP11 CPSF6 GLG1 SF3A2	2.91e-04	251	80	5	28077445
Pubmed	Strain-specific modifier genes governing craniofacial phenotypes.	TSC22D1 SKI	3.40e-04	12	80	2	22371338
Pubmed	Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.	RBM25 YLPM1	3.40e-04	12	80	2	7596406
Pubmed	The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.	YLPM1 SEC16A SKI PRRC2A	3.78e-04	147	80	4	28977470
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	WBP11 CPSF6 YLPM1 MIDEAS	3.87e-04	148	80	4	32538781
Pubmed	RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.	RASA1 SEC16A DVL2 DNM2	3.87e-04	148	80	4	35676246
Pubmed	Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice.	MIA3 CTAGE8	4.01e-04	13	80	2	11839810
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	DCAF1 TSC22D1 MIA3 RBBP6 GLG1 FBRS DNAJC1 RERE SYVN1 SF3A2	4.33e-04	1203	80	10	29180619
Pubmed	Proteomic analysis of the cullin 4B interactome using proximity-dependent biotinylation in living cells.	RBM22 RBM25 CPSF6 ANXA11	4.39e-04	153	80	4	28225217
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	MAGEL2 NFATC4 RBBP6 BICRA YLPM1 UVRAG	4.79e-04	430	80	6	35044719
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	GPALPP1 WBP11 RBBP6 SF3A2 RAI1	4.87e-04	281	80	5	24163370
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	GPALPP1 RBM22 WBP11 MIA3 CPSF6 GLG1 SEC16A DVL2 DNAJC1	5.08e-04	1007	80	9	34597346
Pubmed	Network organization of the human autophagy system.	DCAF1 GLG1 YLPM1 RBM26 UVRAG DNM2	5.22e-04	437	80	6	20562859
Pubmed	Patterning of the third pharyngeal pouch into thymus/parathyroid by Six and Eya1.	FOXN1 FOXI3	5.38e-04	15	80	2	16530750
Pubmed	Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression.	MAGEL2 DMRT3	5.38e-04	15	80	2	23523356
Pubmed	BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis.	TOMM40 WASF1	5.38e-04	15	80	2	12931191
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	MIA3 SETD1B YLPM1 FBRS SEC16A DVL2	5.41e-04	440	80	6	34244565
Pubmed	A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.	RBM22 YLPM1 RBM26 PRRC2A	5.45e-04	162	80	4	31363146
Pubmed	The functional interactome landscape of the human histone deacetylase family.	RBM22 YLPM1 SEC16A RERE MIDEAS	5.53e-04	289	80	5	23752268
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	RBM22 RBM25 AGO2 RBBP6 CPSF6 SEC16A ZC3H6 PRRC2A SF3A2 DNM2	5.72e-04	1247	80	10	27684187
Pubmed	A germline-specific class of small RNAs binds mammalian Piwi proteins.	AGO2 SEC16A SYVN1 PRRC2A SOCS7 DNM2	6.08e-04	450	80	6	16751776
Pubmed	A protein interaction landscape of breast cancer.	DCAF1 RIN1 BICRA ANXA11 POLR1G DNM2 SCAF4	6.51e-04	634	80	7	34591612
Pubmed	HIV-1 accessory proteins--ensuring viral survival in a hostile environment.	DCAF1 DNM2	6.95e-04	17	80	2	18541215
Pubmed	LncRNA ANCR promotes hepatocellular carcinoma metastasis through upregulating HNRNPA1 expression.	RBM25 AGO2	6.95e-04	17	80	2	31868085
Interaction	NCK2 interactions	WBP11 MIA3 CPSF6 YLPM1 RBM26 WIPF3 NFKBID WASF1 PRRC2A SF3A2 SOCS7	6.90e-09	262	80	11	int:NCK2
Interaction	ALG13 interactions	PRR12 RBM25 MIA3 FAM120C CPSF6 FBRS SEC16A RERE PRRC2A	4.59e-08	183	80	9	int:ALG13
Interaction	CTAGE1 interactions	MIA3 CTAGE8 CTAGE15 CTAGE6	4.75e-08	10	80	4	int:CTAGE1
Interaction	WWOX interactions	RBM22 MIA3 DMRT3 CPSF6 ANXA11 YLPM1 FBRS DVL2 MED25 SMR3A PDCD7 PRRC2A SF3A2 SCAF4	1.56e-07	627	80	14	int:WWOX
Interaction	WBP4 interactions	RBM22 WBP11 SETD1B CPSF6 SF3A2 DNM2 SCAF4	2.56e-07	109	80	7	int:WBP4
Interaction	SP7 interactions	PRR12 WBP11 RBM25 RBBP6 BICRA YLPM1 FBRS RERE MIDEAS SCAF4	3.41e-07	304	80	10	int:SP7
Interaction	GRB2 interactions	DCAF1 MLXIPL WBP11 RASA1 RBBP6 CPSF6 YLPM1 WIPF3 DVL2 HCN2 WASF1 PRRC2A SF3A2 SOCS7 DNM2	5.52e-07	806	80	15	int:GRB2
Interaction	PRMT2 interactions	RBM22 WBP11 SETD1B YLPM1 KDM6B PRRC2A	1.65e-06	91	80	6	int:PRMT2
Interaction	KLHL12 interactions	RIN1 CPSF6 PRR13 SEC16A DVL2 MED25	3.60e-06	104	80	6	int:KLHL12
Interaction	TRIP10 interactions	SBK1 RIN1 WBP11 WASF1 SF3A2 DNM2	4.73e-06	109	80	6	int:TRIP10
Interaction	KRTAP6-2 interactions	DMRT3 FOXD4L3 ANXA11 PRR13 NFKBID TPRX1 RERE	9.50e-06	187	80	7	int:KRTAP6-2
Interaction	MAPKAPK2 interactions	WBP11 AGO2 RBBP6 YLPM1 WASF1 PRRC2A	1.55e-05	134	80	6	int:MAPKAPK2
Interaction	GSC interactions	PRR12 FBRS RERE SKI MIDEAS	2.49e-05	87	80	5	int:GSC
Interaction	MIA3 interactions	MIA3 FAM120C CTAGE8 SEC16A CTAGE15 CTAGE6 DNAJC1	3.71e-05	231	80	7	int:MIA3
Interaction	NUP35 interactions	PRR12 RBM22 CPSF6 YLPM1 FBRS SEC16A TOMM40 MIDEAS RAI1	4.60e-05	424	80	9	int:NUP35
Interaction	GAGE5 interactions	WBP11 RBM25 PRRC2A SCAF4	5.39e-05	52	80	4	int:GAGE5
Interaction	EGR2 interactions	PRR12 BICRA FBRS SEC16A RERE MIDEAS	6.11e-05	171	80	6	int:EGR2
Interaction	SNRPC interactions	RBM22 RBM25 RBBP6 CPSF6 YLPM1 TOMM40 RERE SF3A2 SCAF4	6.11e-05	440	80	9	int:SNRPC
Interaction	PLSCR1 interactions	PCED1A DMRT3 CPSF6 ANXA11 PRR13 RERE	6.31e-05	172	80	6	int:PLSCR1
Interaction	CFAP141 interactions	WBP11 RBM26 PRRC2A SCAF4	6.73e-05	55	80	4	int:CFAP141
Interaction	CRX interactions	PRR12 BICRA FBRS RERE SKI MIDEAS RAI1	6.75e-05	254	80	7	int:CRX
Interaction	ANKRD50 interactions	WBP11 RBM25 RBBP6 YLPM1 PRRC2A	7.03e-05	108	80	5	int:ANKRD50
Interaction	SH3RF1 interactions	RIN1 NFKBID SF3A2 SOCS7 DNM2	7.03e-05	108	80	5	int:SH3RF1
Interaction	ATN1 interactions	SETD1B DMRT3 DVL2 RERE SYVN1 PRRC2A	1.00e-04	187	80	6	int:ATN1
Interaction	TLE3 interactions	PRR12 RBM22 RBBP6 FBRS TPRX2 RERE MIDEAS SCAF4	1.23e-04	376	80	8	int:TLE3
Interaction	SNRPF interactions	RBM22 RASA1 CPSF6 YLPM1 PDCD7 SF3A2 SCAF4 SMR3B	1.44e-04	385	80	8	int:SNRPF
Interaction	SMC5 interactions	WBP11 RBM25 RBBP6 CPSF6 BICRA ANXA11 YLPM1 RBM26 SEC16A MIDEAS PRRC2A RAI1 SCAF4	1.46e-04	1000	80	13	int:SMC5
Interaction	CELF1 interactions	WBP11 AGO2 FAM120C CPSF6 YLPM1 PRRC2A SCAF4	1.48e-04	288	80	7	int:CELF1
Interaction	CTAGE15 interactions	MIA3 CTAGE15	1.54e-04	5	80	2	int:CTAGE15
Interaction	DHX8 interactions	GPALPP1 WBP11 RBM25 RBBP6 CPSF6 YLPM1 RBM26	1.61e-04	292	80	7	int:DHX8
Interaction	MEN1 interactions	PRR12 RBM25 SETD1B RBBP6 FAM120C CPSF6 YLPM1 RBM26 RERE POLR1G MIDEAS PRRC2A SF3A2	1.94e-04	1029	80	13	int:MEN1
Interaction	TNRC6C interactions	AGO2 FAM120C SEC16A DVL2 PRRC2A	2.23e-04	138	80	5	int:TNRC6C
Interaction	CTAGE7P interactions	MIA3 CTAGE6	2.31e-04	6	80	2	int:CTAGE7P
Interaction	CTAGE6 interactions	MIA3 CTAGE6	2.31e-04	6	80	2	int:CTAGE6
Interaction	CTAGE8 interactions	MIA3 CTAGE8	2.31e-04	6	80	2	int:CTAGE8
Interaction	CPSF6 interactions	RBM22 WBP11 RBM25 RBBP6 CPSF6 YLPM1 RBM26 SF3A2 SCAF4	2.35e-04	526	80	9	int:CPSF6
Interaction	DDX20 interactions	AGO2 FAM120C CPSF6 SEC16A KDM6B PRRC2A	2.67e-04	224	80	6	int:DDX20
Interaction	SMG7 interactions	PRR12 AGO2 FAM120C CPSF6 YLPM1 SEC16A PRRC2A	2.76e-04	319	80	7	int:SMG7
Interaction	RNPS1 interactions	GPALPP1 RBM25 RBBP6 CPSF6 BICRA DVL2 SF3A2 SCAF4	2.82e-04	425	80	8	int:RNPS1
Interaction	ITSN2 interactions	RBM22 CPSF6 YLPM1 WIPF3 DNM2	2.99e-04	147	80	5	int:ITSN2
Interaction	PSENEN interactions	WBP11 RBM26 PRRC2A SCAF4	3.04e-04	81	80	4	int:PSENEN
Interaction	FXR1 interactions	PCED1A MIA3 AGO2 CPSF6 PRR13 RBM26 SEC16A MAPK7 PRRC2A DNM2	3.47e-04	679	80	10	int:FXR1
Interaction	CEBPA interactions	GPALPP1 PRR12 RBM22 WBP11 NFATC4 CPSF6 BICRA RBM26 MIDEAS PRRC2A SF3A2 RAI1 DNM2 SCAF4	3.56e-04	1245	80	14	int:CEBPA
Interaction	PRPF40A interactions	WBP11 RBM25 CPSF6 YLPM1 PDCD7 WASF1 SF3A2 SCAF4	3.89e-04	446	80	8	int:PRPF40A
Interaction	ACTC1 interactions	WBP11 RBM25 RBBP6 CPSF6 BICRA YLPM1 WIPF3 FMN2 SF3A2 SCAF4	4.12e-04	694	80	10	int:ACTC1
Interaction	EYA4 interactions	PRR12 SOBP CPSF6 BICRA FBRS MIDEAS	4.12e-04	243	80	6	int:EYA4
Interaction	OSTF1 interactions	NUTM1 WASF1 SF3A2 SOCS7	4.54e-04	90	80	4	int:OSTF1
Interaction	NXN interactions	FAM120C DVL2 WASF1	4.60e-04	38	80	3	int:NXN
Interaction	FOXI1 interactions	PRR12 FBRS NFKBID TOMM40	4.93e-04	92	80	4	int:FOXI1
Interaction	PRM2 interactions	RBM26 PRRC2A SCAF4	4.97e-04	39	80	3	int:PRM2
Interaction	SMARCC2 interactions	FOXN1 RBM25 CPSF6 BICRA YLPM1 TPRX2 POLR1G	5.06e-04	353	80	7	int:SMARCC2
Interaction	AR interactions	PRR12 RBM25 RASA1 CPSF6 YLPM1 RBM26 FBRS SEC16A RERE SKI MIDEAS RAI1	5.18e-04	992	80	12	int:AR
Interaction	SNRPB2 interactions	RBM22 WBP11 RBM25 CPSF6 PDCD7 SF3A2	5.32e-04	255	80	6	int:SNRPB2
Interaction	GARRE1 interactions	SHROOM1 AGO2 FAM120C SEC16A PRRC2A	5.36e-04	167	80	5	int:GARRE1
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	PRR12 WTIP BICRA FGF21 PRR19 MED25 NFKBID TPRX1 TPRX2 TOMM40 POLR1G	7.04e-06	1192	80	11	chr19q13
Cytoband	4q13.3	SMR3A PRR27 SMR3B	5.57e-05	42	80	3	4q13.3
Cytoband	7q35	CTAGE8 CTAGE15 CTAGE6	1.25e-04	55	80	3	7q35
Cytoband	Ensembl 112 genes in cytogenetic band chr7q35	CTAGE8 CTAGE15 CTAGE6	2.15e-04	66	80	3	chr7q35
Cytoband	19q13.3	BICRA MED25 POLR1G	4.09e-04	82	80	3	19q13.3
Cytoband	14q24.3	RBM25 YLPM1 MIDEAS	5.91e-04	93	80	3	14q24.3
Cytoband	19q13.33	PRR12 FGF21 TPRX1	8.64e-04	106	80	3	19q13.33
Cytoband	Ensembl 112 genes in cytogenetic band chr4q13	SMR3A PRR27 SMR3B	2.66e-03	157	80	3	chr4q13
GeneFamily	CTAGE family	CTAGE8 CTAGE15 CTAGE6	7.81e-06	15	48	3	907
GeneFamily	RNA binding motif containing	RBM22 RBM25 SETD1B CPSF6 RBM26 SCAF4	2.02e-05	213	48	6	725
GeneFamily	Zinc fingers CCCH-type	RBM22 RBM26 ZC3H6	1.08e-04	35	48	3	73
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	DNAJC1 RERE MIDEAS	3.75e-04	53	48	3	532
GeneFamily	PRD class homeoboxes and pseudogenes	TPRX1 TPRX2 RAX	1.87e-03	92	48	3	521
Drug	Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A	GPALPP1 DCAF1 MED25 RERE MAPK7 WASF1 PRRC2A	4.48e-06	193	78	7	3262_UP
Drug	6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine	SBK1 PRR12 RERE KDM6B SKI	2.92e-05	104	78	5	ctd:C000595015
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA	RBBP6 CPSF6 YLPM1 DVL2 DNM2 SEMA4C	4.07e-05	184	78	6	1064_DN
Drug	Clioquinol [130-26-7]; Up 200; 13uM; HL60; HT_HG-U133A	MLXIPL TSC22D1 FGF21 FBRS SOCS7 SEMA4C	4.73e-05	189	78	6	3084_UP
Drug	Zidovudine, AZT [30516-87-1]; Down 200; 15uM; PC3; HT_HG-U133A	FAM120C FBRS MED25 SMR3A MAPK7 SF3A2	5.31e-05	193	78	6	6733_DN
Drug	Benzydamine hydrochloride [132-69-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A	RIN1 FAM120C DVL2 SMR3A RERE MAPK7	5.95e-05	197	78	6	7169_UP
Drug	Antazoline hydrochloride [2508-72-7]; Down 200; 13.2uM; HL60; HG-U133A	RIN1 SETD1B FBRS PRRC2A DNM2 SCAF4	5.95e-05	197	78	6	1556_DN
Drug	Carcinine [56897-53-1]; Up 200; 22uM; MCF7; HT_HG-U133A	MIA3 SETD1B GLG1 MAPK7 KDM6B SCAF4	5.95e-05	197	78	6	3242_UP
Drug	PNU-0293363 [326823-19-2]; Up 200; 10uM; PC3; HT_HG-U133A	RBM25 SETD1B GLG1 MED25 MUC5AC SF3A2	5.95e-05	197	78	6	6563_UP
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; PC3; HT_HG-U133A	GPALPP1 DCAF1 YLPM1 KDM6B POLR1G PRRC2A	5.95e-05	197	78	6	1215_DN
Drug	Cyclacillin [3485-14-1]; Down 200; 11.8uM; PC3; HT_HG-U133A	FBN1 SOBP MED25 SMR3A RERE SEMA4C	6.12e-05	198	78	6	4536_DN
Drug	(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; PC3; HT_HG-U133A	DCAF1 SOBP DVL2 MED25 RERE SCAF4	6.29e-05	199	78	6	4543_DN
Drug	Hesperidin [520-26-3]; Up 200; 6.6uM; MCF7; HT_HG-U133A	DCAF1 FBN1 ANXA11 YLPM1 DVL2 MUC5AC	6.47e-05	200	78	6	2648_UP
Drug	Ethosuximide [77-67-8]; Down 200; 28.4uM; PC3; HT_HG-U133A	DCAF1 FAM120C CPSF6 YLPM1 DVL2 SEMA4C	6.47e-05	200	78	6	7308_DN
Disease	Shprintzen-Goldberg syndrome	FBN1 SKI	5.71e-06	2	71	2	C1321551
Disease	migraine disorder, type 1 diabetes mellitus	RERE FOXI3	5.68e-05	5	71	2	MONDO_0005147, MONDO_0005277
Disease	Chromosome 1p36 Deletion Syndrome	RERE SKI	5.68e-05	5	71	2	C1842870
Disease	triglycerides in HDL measurement	MLXIPL FGF21 TOMM40	2.87e-04	53	71	3	EFO_0022317
Disease	level of Diacylglycerol (18:1_18:2) in blood serum	MLXIPL TOMM40	3.71e-04	12	71	2	OBA_2045171
Disease	respiratory system disease	DCAF1 RERE MUC5AC UVRAG	4.21e-04	145	71	4	EFO_0000684
Disease	granulocyte percentage of myeloid white cells	MLXIPL GLG1 PRR13 DNAJC1 KDM6B	4.75e-04	268	71	5	EFO_0007997
Disease	severe acute respiratory syndrome, COVID-19	DMRT3 CPSF6 RBM26 CHSY3 TOMM40 PRR27	7.29e-04	447	71	6	EFO_0000694, MONDO_0100096
Disease	HMG CoA reductase inhibitor use measurement	MLXIPL MIA3 TOMM40 SKI	1.13e-03	189	71	4	EFO_0009932
Disease	fat intake measurement	MLXIPL FGF21	1.28e-03	22	71	2	EFO_0010809
Disease	Agents acting on the renin-angiotensin system use measurement	MIA3 NFATC4 CPSF6 KDM6B POLR1G	1.29e-03	335	71	5	EFO_0009931
Disease	body fat percentage, coronary artery disease	MIA3 TOMM40	1.52e-03	24	71	2	EFO_0001645, EFO_0007800
Disease	serum non-albumin protein measurement	SBK1 MIA3 FGF21 PRRC2A DNM2	1.79e-03	361	71	5	EFO_0004568
Disease	monocyte percentage of leukocytes	MLXIPL GLG1 PRR13 SEC16A DNAJC1 RERE KDM6B	1.87e-03	731	71	7	EFO_0007989
Disease	prostate carcinoma, breast carcinoma, ovarian carcinoma	RIN1 DNAJC1	1.93e-03	27	71	2	EFO_0000305, EFO_0001075, EFO_0001663
Disease	sodium measurement	MLXIPL FGF21 DNAJC1	1.99e-03	103	71	3	EFO_0009282

Protein segments in the cluster

Peptide	Gene	Start	Entry
GQPPVTYPGQPPVPL	ANXA11	146	P50995
PGFIPPPLAPVRGPL	CTAGE6	691	Q86UF2
PGFIPPPLAPVRGPL	CTAGE8	691	P0CG41
PGFIPPPLAPVRGPL	CTAGE15	691	A4D2H0
QLGLVPFPPPPPRTP	DNAJC1	16	Q96KC8
PVPPAVQPPGAPPVR	DVL2	691	O14641
GPALAPPAPPPPIQG	AGO2	6	Q9UKV8
PPPPQPQPLPAGVAK	RAI1	126	Q7Z5J4
GPPAVVNIALPPPPG	RBM22	356	Q9NW64
VNIALPPPPGIAPPP	RBM22	361	Q9NW64
ALPPGIPPPQFPGFP	RBM25	16	P49756
FPAQPPVVEGPPPPG	RBM26	331	Q5T8P6
PLPPPPYLPPLGAGL	RASA1	136	P20936
PGVLPYFPPGLPPPD	MAPK7	681	Q13164
PQPRPPQGPLALPGP	DCAF1	931	Q9Y4B6
PPPPPGAAAGPFLQP	FOXI3	81	A8MTJ6
QPPALGGPIVPAPPL	MAGEL2	81	Q9UJ55
PPSGPPQFPAVVPGP	NFKBID	11	Q8NI38
PRPGPLLGAPAPPQP	FOXD4L3	231	Q6VB84
EQTGLPPGLPLPPPP	KDM6B	236	O15054
QLIVEPGPPGPPGPP	COL23A1	406	Q86Y22
FFGQGRPGPPPPQPP	PDCD7	6	Q8N8D1
AFPPPLPQRPGPFPG	PDCD7	36	Q8N8D1
PGVNFVPGPLPPPIP	PCED1A	376	Q9H1Q7
PPALPEPPGILAPQP	FGF21	171	Q9NSA1
SGPPPPGPILRPQNP	MED25	626	Q71SY5
PLPPACPLPGFVPVP	MUC5AC	5316	P98088
YPPPAPGIPPVNPLA	PRR13	81	Q9NZ81
PPAVRGPTPGPPLIP	DNM2	781	P50570
TLPLPPGVPPPQFSP	RBBP6	571	Q7Z6E9
PGVPPPQFSPQFPPG	RBBP6	576	Q7Z6E9
PGLPPQPPPPVAQLV	NUTM1	156	Q86Y26
VPPLPPRGFPFVPPS	PRR27	101	Q6MZM9
QPPQPPFPAGGPPAR	GLG1	86	Q92896
FPPAVPGLPPGLPPA	FBRS	21	Q9HAH7
GPPPPGQVLPPPLAG	CPSF6	251	Q16630
PSPLAGPLQPPFPQP	DMRT3	351	Q9NQL9
LGPIPPVLPVPPGFP	FBN1	406	P35555
PVLPVPPGFPPGPQI	FBN1	411	P35555
PPGFPPGPQIPVPRP	FBN1	416	P35555
PPPPPPQLPGARVLV	FAM120C	106	Q9NX05
PPRPIIGPALPPGFI	GPALPP1	106	Q8IXQ4
RQGPPPPNPVAAFPP	MIDEAS	231	Q6PJG2
PCPPPQAPPTLPGIF	BICRA	821	Q9NZM4
AAIPPPPPLPGAGIP	FMN2	951	Q9NZ56
AGIPPPPPLPGAGIP	FMN2	1006	Q9NZ56
AGIPPPPPLPGAGIP	FMN2	1061	Q9NZ56
LPGAGIPPPPPLPGV	FMN2	1091	Q9NZ56
AGIPPPPPLPGAGIP	FMN2	1116	Q9NZ56
PGAGIPPPPPLPRVG	FMN2	1136	Q9NZ56
AGIPPPPPLPGVGIP	FMN2	1171	Q9NZ56
QPPAFTPPLGIPPPG	SCAF4	696	O95104
PVPVPEPGLAPQGPP	SBK1	386	Q52WX2
ELGQRVGLFPPPPPP	HCN2	706	Q9UL51
VGLFPPPPPPPQVTS	HCN2	711	Q9UL51
PPNFPQGLLPPFPPG	SYVN1	366	Q86TM6
VPQPPPGPAAALPPG	UVRAG	11	Q9P2Y5
AVPPPPVPVLPGAVP	RIN1	261	Q13671
GGPVPPPIRYGPPPQ	MIA3	1776	Q5JRA6
PPPYGAAPIGIPRPP	NFATC4	51	Q14934
GLAPPGPPQPLFPQP	FOXN1	461	O15353
PGLPQAPQGPSPRPP	PRRC2A	1501	P48634
QPIPASPPPQIPPGL	POLR1G	131	O15446
PPGPLAPPQPFGPGF	SMR3B	31	P02814
PPAAPPPAGLQPLGP	SLAIN1	66	Q8ND83
PPGTCPPVQPPFPLL	SHROOM1	836	Q2M3G4
PGPQEPLPPTLGPPL	SHISA8	186	B8ZZ34
ILPPLPPFPPGLFPV	SETD1B	741	Q9UPS6
PPPLPLLPPCGYPGL	WIPF3	261	A6NGB9
QHPFVPGGPPPITPP	RERE	1036	Q9P2R6
APPVQTPLPGAPPPQ	TSC22D1	611	Q15714
GGPDLPLVLPPPPPQ	PRR12	786	Q9ULL5
PAAAVPGPPPLPGLP	PRR12	1426	Q9ULL5
PPPGIPGQPLPSPTR	SEMA4C	761	Q9C0C4
PAKVPGLEPCPPPPF	MLXIPL	401	Q9NP71
GPPQLPPPAPGVHPP	SF3A2	276	Q15428
LPAIQPPPPVLPGPF	SKI	76	P12755
SPPLGPGLQPLAPPP	RAX	286	Q9Y2V3
PPNAGQPPPPLPVIA	CHSY3	211	Q70JA7
PGPIPAPIPGPAQIP	TPRX1	96	Q8N7U7
PGPISVPIPGPIPGP	TPRX1	196	Q8N7U7
VPIPGPIPGPISGPI	TPRX1	201	Q8N7U7
PIPGPISGPNPGPIP	TPRX1	226	Q8N7U7
PPLPPGPPEIVGPQN	ZC3H6	516	P61129
FPVPLPPGPLEPGPG	SEC16A	1971	O15027
PPPRPWGVGLPQPLP	PRR19	296	A6NJB7
VQPPASIGPPLGVPP	SOBP	366	A7XYQ1
IPPSPPPPYGPGRIQ	SMR3A	76	Q99954
LLQPPGPELPPVPFP	SOCS7	151	O14512
PGIPPPGVPQGIPPQ	YLPM1	631	P49750
PAGPPPPPAPALVGL	TOMM40	11	O96008
ALVGLPPPPPSPPGF	TOMM40	21	O96008
GPAPFPLPALPLPPG	WTIP	176	A6NIX2
PAVPPPPAPLQIAPG	WASF1	366	Q92558
GPPPGPPPPQVVQMY	WBP11	201	Q9Y2W2
LVPPLGPAPPGLFPP	WBP11	511	Q9Y2W2
GPAPPGLFPPAPLPN	WBP11	516	Q9Y2W2
QGPPPTVPPPPRVVD	TREX1	51	Q9NSU2
VPAPGPGPIPAPIPG	TPRX2	161	P0DV77
PGPIPAPIPGPAQIP	TPRX2	166	P0DV77